|
1
|
Crosbie EJ, Einstein MH, Franceschi S and
Kitchener HC: Human papillomavirus and cervical cancer. Lancet.
382:889–899. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Partridge EE, Abu-Rustum N, Giuliano A,
Massad S, McClure J, Dwyer M and Hughes M: National comprehensive
cancer network: Cervical cancer screening. J Natl Compr Canc Netw.
12:333–341; quiz 341. 2014.
|
|
3
|
Liu X, Wang D, Liu H, Feng Y, Zhu T, Zhang
L, Zhu B and Zhang Y: Knockdown of astrocyte elevated gene-1
(AEG-1) in cervical cancer cells decreases their invasiveness,
epithelial to mesenchymal transition, and chemoresistance. Cell
Cycle. 13:1702–1707. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kim CJ, Jeong JK, Park M, Park TS, Park
TC, Namkoong SE and Park JS: HPV oligonucleotide microarray-based
detection of HPV genotypes in cervical neoplastic lesions. Gynecol
Oncol. 89:210–217. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Jung HY, Fattet L and Yang J: Molecular
pathways: Linking tumor microenvironment to epithelial-mesenchymal
transition in metastasis. Clin Cancer Res. 21:962–968. 2015.
View Article : Google Scholar
|
|
6
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelial-mesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kalluri R and Neilson EG:
Epithelial-mesenchymal transition and its implications for
fibrosis. J Clin Invest. 112:1776–1784. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fazioli F, Minichiello L, Matoska V,
Castagnino P, Miki T, Wong WT and Di Fiore PP: Eps8, a substrate
for the epidermal growth factor receptor kinase, enhances
EGF-dependent mitogenic signals. EMBO J. 12:3799–3808.
1993.PubMed/NCBI
|
|
9
|
Matoskova B, Wong WT, Salcini AE, Pelicci
PG and Di Fiore PP: Constitutive phosphorylation of eps8 in tumor
cell lines: Relevance to malignant transformation. Mol Cell Biol.
15:3805–3812. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Maa MC, Lee JC, Chen YJ, Chen YJ, Lee YC,
Wang ST, Huang CC, Chow NH and Leu TH: Eps8 facilitates cellular
growth and motility of colon cancer cells by increasing the
expression and activity of focal adhesion kinase. J Biol Chem.
282:19399–19409. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Xu M, Shorts-Cary L, Knox AJ,
Kleinsmidt-DeMasters B, Lillehei K and Wierman ME: Epidermal growth
factor receptor pathway substrate 8 is overexpressed in human
pituitary tumors: Role in proliferation and survival.
Endocrinology. 150:2064–2071. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yap LF, Jenei V, Robinson CM, Moutasim K,
Benn TM, Threadgold SP, Lopes V, Wei W, Thomas GJ and Paterson IC:
Upregulation of Eps8 in oral squamous cell carcinoma promotes cell
migration and invasion through integrin-dependent Rac1 activation.
Oncogene. 28:2524–2534. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Bashir M, Kirmani D, Bhat HF, Baba RA,
Hamza R, Naqash S, Wani NA, Andrabi KI, Zargar MA and Khanday FA:
P66shc and its downstream Eps8 and Rac1 proteins are upregulated in
esophageal cancers. Cell Commun Signal. 8:132010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Welsch T, Endlich K, Giese T, Büchler MW
and Schmidt J: Eps8 is increased in pancreatic cancer and required
for dynamic actin-based cell protrusions and intercellular
cytoskeletal organization. Cancer Lett. 255:205–218. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liu PS, Jong TH, Maa MC and Leu TH: The
interplay between Eps8 and IRSp53 contributes to Src-mediated
transformation. Oncogene. 29:3977–3989. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wang H, Patel V, Miyazaki H, Gutkind JS
and Yeudall WA: Role for EPS8 in squamous carcinogenesis.
Carcinogenesis. 30:165–174. 2009. View Article : Google Scholar
|
|
17
|
Chen YJ, Shen MR, Chen YJ, Maa MC and Leu
TH: Eps8 decreases chemosensitivity and affects survival of
cervical cancer patients. Mol Cancer Ther. 7:1376–1385. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ackland ML, Newgreen DF, Fridman M,
Waltham MC, Arvanitis A, Minichiello J, Price JT and Thompson EW:
Epidermal growth factor-induced epithelia-mesenchymal transition in
human breast carcinoma cells. Lab Invest. 83:435–448. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Hagemann T, Bozanovic T, Hooper S, Ljubic
A, Slettenaar VI, Wilson JL, Singh N, Gayther SA, Shepherd JH and
Van Trappen PO: Molecular profiling of cervical cancer progression.
Br J Cancer. 96:321–328. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Shen MR, Hsu YM, Hsu KF, Chen YF, Tang MJ
and Chou CY: Insulin-like growth factor 1 is a potent stimulator of
cervical cancer cell invasiveness and proliferation that is
modulated by alphavbeta3 integrin signaling. Carcinogenesis.
27:962–971. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Adam L, Zhong M, Choi W, Qi W, Nicoloso M,
Arora A, Calin G, Wang H, Siefker-Radtke A, McConkey D, et al:
MiR-200 expression regulates epithelial-to-mesenchymal transition
in bladder cancer cells and reverses resistance to epidermal growth
factor receptor therapy. Clin Cancer Res. 15:5060–5072. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Cannito S, Novo E, di Bonzo LV, Busletta
C, Colombatto S and Parola M: Epithelial-mesenchymal transition:
From molecular mechanisms, redox regulation to implications in
human health and disease. Antioxid Redox Signal. 12:1383–1430.
2010. View Article : Google Scholar
|
|
23
|
Wang Z, Li Y, Ahmad A, Azmi AS, Kong D,
Banerjee S and Sarkar FH: Targeting miRNAs involved in cancer stem
cell and EMT regulation: An emerging concept in overcoming drug
resistance. Drug Resist Updat. 13:109–118. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2−ΔΔCT method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
|
25
|
Qureshi R, Arora H and Rizvi MA: EMT in
cervical cancer: Its role in tumour progression and response to
therapy. Cancer Lett. 356:321–331. 2015. View Article : Google Scholar
|
|
26
|
Polyak K and Weinberg RA: Transitions
between epithelial and mesenchymal states: Acquisition of malignant
and stem cell traits. Nat Rev Cancer. 9:265–273. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Acloque H, Adams MS, Fishwick K,
Bronner-Fraser M and Nieto MA: Epithelial-mesenchymal transitions:
The importance of changing cell state in development and disease. J
Clin Invest. 119:1438–1449. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
28
|
Castagnino P, Biesova Z, Wong WT, Fazioli
F, Gill GN and Di Fiore PP: Direct binding of eps8 to the
juxtamembrane domain of EGFR is phosphotyrosine- and
SH2-independent. Oncogene. 10:723–729. 1995.PubMed/NCBI
|
|
29
|
Disanza A, Mantoani S, Hertzog M, Gerboth
S, Frittoli E, Steffen A, Berhoerster K, Kreienkamp HJ, Milanesi F,
Di Fiore PP, et al: Regulation of cell shape by Cdc42 is mediated
by the synergic actin-bundling activity of the Eps8-IRSp53 complex.
Nat Cell Biol. 8:1337–1347. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
30
|
Goicoechea S, Arneman D, Disanza A,
Garcia-Mata R, Scita G and Otey CA: Palladin binds to Eps8 and
enhances the formation of dorsal ruffles and podosomes in vascular
smooth muscle cells. J Cell Sci. 119:3316–3324. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Innocenti M, Frittoli E, Ponzanelli I,
Falck JR, Brachmann SM, Di Fiore PP and Scita G: Phosphoinositide
3-kinase activates Rac by entering in a complex with Eps8, Abi1,
and Sos-1. J Cell Biol. 160:17–23. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wang H, Teh MT, Ji Y, Patel V,
Firouzabadian S, Patel AA, Gutkind JS and Yeudall WA: EPS8
upregulates FOXM1 expression, enhancing cell growth and motility.
Carcinogenesis. 31:1132–1141. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chu PY, Liou JH, Lin YM, Chen CJ, Chen MK,
Lin SH, Yeh CM, Wang HK, Maa MC, Leu TH, et al: Expression of Eps8
correlates with poor survival in oral squamous cell carcinoma. Asia
Pac J Clin Oncol. 8:e77–e81. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kang H, Wilson CS, Harvey RC, Chen IM,
Murphy MH, Atlas SR, Bedrick EJ, Devidas M, Carroll AJ, Robinson
BW, et al: Gene expression profiles predictive of outcome and age
in infant acute lymphoblastic leukemia: A children's oncology group
study. Blood. 119:1872–1881. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Chen H, Wu X, Pan ZK and Huang S:
Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer
metastasis. Cancer Res. 70:9979–9990. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Lim J and Thiery JP:
Epithelial-mesenchymal transitions: Insights from development.
Development. 139:3471–3486. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Schipper JH, Frixen UH, Behrens J, Unger
A, Jahnke K and Birchmeier W: E-cadherin expression in squamous
cell carcinomas of head and neck: Inverse correlation with tumor
dedifferentiation and lymph node metastasis. Cancer Res.
51:6328–6337. 1991.PubMed/NCBI
|
|
38
|
Shiozaki H, Tahara H, Oka H, Miyata M,
Kobayashi K, Tamura S, Iihara K, Doki Y, Hirano S, Takeichi M, et
al: Expression of immunoreactive E-cadherin adhesion molecules in
human cancers. Am J Pathol. 139:17–23. 1991.PubMed/NCBI
|
|
39
|
Kadowaki T, Shiozaki H, Inoue M, Tamura S,
Oka H, Doki Y, Iihara K, Matsui S, Iwazawa T, Nagafuchi A, et al:
E-cadherin and alpha-catenin expression in human esophageal cancer.
Cancer Res. 54:291–296. 1994.PubMed/NCBI
|
|
40
|
Bowie GL, Caslin AW, Roland NJ, Field JK,
Jones AS and Kinsella AR: Expression of the cell-cell adhesion
molecule E-cadherin in squamous cell carcinoma of the head and
neck. Clin Otolaryngol Allied Sci. 18:196–201. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Koseki S, Aoki T, Ansai S, Hozumi Y,
Mitsuhashi Y and Kondo S: An immunohistochemical study of
E-cadherin expression in human squamous cell carcinoma of the skin:
Relationship between decreased expression of E-cadherin in the
primary lesion and regional lymph node metastasis. J Dermatol.
26:416–422. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Wu H, Lotan R, Menter D, Lippman SM and Xu
XC: Expression of E-cadherin is associated with squamous
differentiation in squamous cell carcinomas. Anticancer Res.
20:1385–1390. 2000.PubMed/NCBI
|
|
43
|
Berx G, Staes K, van Hengel J, Molemans F,
Bussemakers MJ, van Bokhoven A and van Roy F: Cloning and
characterization of the human invasion suppressor gene E-cadherin
(CDH1). Genomics. 26:281–289. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Prognostic significance of CyclinD1 and
E-Cadherin in patients with esophageal squamous cell carcinoma:
Multiinstitutional retrospective analysis. Research committee on
malignancy of esophageal cancer, Japanese society for esophageal
diseases. J Am Coll Surg. 192:708–718. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Helfand BT, Mendez MG, Murthy SN, Shumaker
DK, Grin B, Mahammad S, Aebi U, Wedig T, Wu YI, Hahn KM, et al:
Vimentin organization modulates the formation of lamellipodia. Mol
Biol CellMol Biol Cell. 22:1274–1289. 2011. View Article : Google Scholar
|
|
46
|
Adam SA and Gerace L: Cytosolic proteins
that specifically bind nuclear location signals are receptors for
nuclear import. Cell. 66:837–847. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Moody SE, Perez D, Pan TC, Sarkisian CJ,
Portocarrero CP, Sterner CJ, Notorfrancesco KL, Cardiff RD and
Chodosh LA: The transcriptional repressor Snail promotes mammary
tumor recurrence. Cancer Cell. 8:197–209. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Wu Y and Zhou BP: New insights of
epithelial-mesenchymal transition in cancer metastasis. Acta
Biochim Biophys Sin (Shanghai). 40:643–650. 2008. View Article : Google Scholar
|
|
49
|
Guarino M: Epithelial-mesenchymal
transition and tumour invasion. Int J Biochem Cell Biol.
39:2153–2160. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Chen KC, Chen CY, Lin CR, Yang TY, Chen
TH, Wu LC and Wu CC: Luteolin attenuates TGF-β1-induced
epithelial-mesenchymal transition of lung cancer cells by
interfering in the PI3K/Akt-NF-κB Snail pathway. Life Sci.
93:924–933. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Zhang B, Yin C, Li H, Shi L, Liu N, Sun Y,
Lu S, Liu Y, Sun L, Li X, et al: Nir1 promotes invasion of breast
cancer cells by binding to chemokine (C-C motif) ligand 18 through
the PI3K/Akt/GSK3β/Snail signalling pathway. Eur J Cancer.
49:3900–3913. 2013. View Article : Google Scholar : PubMed/NCBI
|
