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Article

Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules

  • Authors:
    • Dan Ilkovitch
    • Laura K. Ferris
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, Cleveland Clinic Florida, Weston, FL 33331, USA, Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
  • Pages: 3935-3940
    |
    Published online on: August 26, 2016
       https://doi.org/10.3892/mmr.2016.5685
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Abstract

Psoriasis is a debilitating chronic inflammatory disease. In addition to the characteristic effects on the skin, chronic inflammation associated with the disease is recognized to contribute to cardiovascular, hepatic and renal comorbidities. Immature myeloid regulatory cells, known as myeloid‑derived suppressor cells (MDSCs), have been demonstrated to accumulate in various diseases and chronic inflammatory states, including inflammatory bowel disease and various types of cancer. The results of the present study, obtained using flow cytometry and cell culture analysis of peripheral blood mononuclear cells from psoriasis and healthy patients, revealed that MDSC levels are significantly increased in the blood of patients with psoriasis compared with healthy controls. Furthermore, these cells are capable of producing various molecules, including matrix metalloproteinase‑9 and‑1, interleukin‑8, growth‑related oncogene, and monocyte chemoattractant protein 1. These molecules may recruit additional immune cells involved in the pathogenesis of the disease, and contribute to the chronic inflammatory state in these patients. Therefore, MDSCs, which have various immune regulatory functions, may contribute to the pathogenesis of psoriasis as a systemic inflammatory disease.
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1 

Ogdie A, Yu Y, Haynes K, Love TJ, Maliha S, Jiang Y, Troxel AB, Hennessy S, Kimmel SE, Margolis DJ, et al: Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: A population-based cohort study. Ann Rheum Dis. 74:326–332. 2015. View Article : Google Scholar :

2 

Chi CC, Wang J, Chen YF, Wang SH, Chen FL and Tung TH: Risk of incident chronic kidney disease and end-stage renal disease in patients with psoriasis: A nationwide population-based cohort study. J Dermatol Sci. 78:232–238. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Wan J, Wang S, Haynes K, Denburg MR, Shin DB and Gelfand JM: Risk of moderate to advanced kidney disease in patients with psoriasis: Population based cohort study. BMJ. 347:f59612013. View Article : Google Scholar : PubMed/NCBI

4 

Ganzetti G, Campanati A and Offidani A: Non-alcoholic fatty liver disease and psoriasis: So far, so near. World J Hepatol. 7:315–326. 2015. View Article : Google Scholar : PubMed/NCBI

5 

Wang CQ, Suarez-Farinas M, Nograles KE, Mimoso CA, Shrom D, Dow ER, Heffernan MP, Hoffman RW and Krueger JG: IL-17 induces inflammation-associated gene products in blood monocytes, and treatment with ixekizumab reduces their expression in psoriasis patient blood. J Invest Dermatol. 134:2990–2993. 2014. View Article : Google Scholar : PubMed/NCBI

6 

Ilkovitch D: Role of immune-regulatory cells in skin pathology. J Leukoc Biol. 89:41–49. 2011. View Article : Google Scholar :

7 

Ilkovitch D and Lopez DM: Urokinase-mediated recruitment of myeloid-derived suppressor cells and their suppressive mechanisms are blocked by MUC1/sec. Blood. 113:4729–4739. 2009. View Article : Google Scholar : PubMed/NCBI

8 

Bronte V, Brandau S, Chen SH, Colombo MP, Frey AB, Greten TF, Mandruzzato S, Murray PJ, Ochoa A, Ostrand-Rosenberg S, et al: Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards. Nat Commun. 7:121502016. View Article : Google Scholar : PubMed/NCBI

9 

Gabrilovich DI, Bronte V, Chen SH, Colombo MP, Ochoa A, Ostrand-Rosenberg S and Schreiber H: The terminology issue for myeloid-derived suppressor cells. Cancer Res. 67:425–426. 2007. View Article : Google Scholar : PubMed/NCBI

10 

Liu C, Yu S, Kappes J, Wang J, Grizzle WE, Zinn KR and Zhang HG: Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood. 109:4336–4342. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Sinha P, Clements VK, Bunt SK, Albelda SM and Ostrand-Rosenberg S: Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J Immunol. 179:977–983. 2007. View Article : Google Scholar : PubMed/NCBI

12 

Ilkovitch D and Lopez DM: The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression. Cancer Res. 69:5514–5521. 2009. View Article : Google Scholar : PubMed/NCBI

13 

Huang B, Pan PY, Li Q, Sato AI, Levy DE, Bromberg J, Divino CM and Chen SH: Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 66:1123–1131. 2006. View Article : Google Scholar : PubMed/NCBI

14 

Youn JI, Nagaraj S, Collazo M and Gabrilovich DI: Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol. 181:5791–5802. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Filipazzi P, Valenti R, Huber V, Canese P, Iero M, Castelli C, Mariani L, Parmiani G and Rivoltini L: Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol. 25:2546–2553. 2007. View Article : Google Scholar : PubMed/NCBI

16 

Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ and Montero AJ: Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother. 58:49–59. 2009. View Article : Google Scholar

17 

Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, Carbone DP and Gabrilovich DI: Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer. J Immunol. 166:678–689. 2001. View Article : Google Scholar

18 

Kusmartsev S, Su Z, Heiser A, Dannull J, Eruslanov E, Kübler H, Yancey D, Dahm P and Vieweg J: Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res. 14:8270–8278. 2008. View Article : Google Scholar : PubMed/NCBI

19 

Hoechst B, Ormandy LA, Ballmaier M, Lehner F, Krüger C, Manns MP, Greten TF and Korangy F: A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Gastroenterology. 135:234–243. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Haile LA, von Wasielewski R, Gamrekelashvili J, Krüger C, Bachmann O, Westendorf AM, Buer J, Liblau R, Manns MP, Korangy F and Greten TF: Myeloid-derived suppressor cells in inflammatory bowel disease: A new immunoregulatory pathway. Gastroenterology. 135:871–881. e1–5. 2008. View Article : Google Scholar : PubMed/NCBI

21 

Makarenkova VP, Bansal V, Matta BM, Perez LA and Ochoa JB: CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress. J Immunol. 176:2085–2094. 2006. View Article : Google Scholar : PubMed/NCBI

22 

Noel JG, Osterburg A, Wang Q, Guo X, Byrum D, Schwemberger S, Goetzman H, Caldwell CC and Ogle CK: Thermal injury elevates the inflammatory monocyte subpopulation in multiple compartments. Shock. 28:684–693. 2007.PubMed/NCBI

23 

Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, Kelly-Scumpia KM, O'Malley KA, Wynn JL, Antonenko S, Al-Quran SZ, et al: MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med. 204:1463–1474. 2007. View Article : Google Scholar : PubMed/NCBI

24 

De Santo C, Salio M, Masri SH, Lee LY, Dong T, Speak AO, Porubsky S, Booth S, Veerapen N, Besra GS, et al: Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans. J Clin Invest. 118:4036–4048. 2008. View Article : Google Scholar : PubMed/NCBI

25 

Dugast AS, Haudebourg T, Coulon F, Heslan M, Haspot F, Poirier N, Vuillefroy de Silly R, Usal C, Smit H, Martinet B, et al: Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion. J Immunol. 180:7898–7906. 2008. View Article : Google Scholar : PubMed/NCBI

26 

Soler DC, Young AB, Fiessinger L, Galimberti F, Debanne S, Groft S, McCormick TS and Cooper KD: Increased, but functionally impaired, CD14(+) HLA-DR(-/low) myeloid-derived suppressor cells in psoriasis: A mechanism of dysregulated T cells. J Invest Dermatol. 136:798–808. 2016. View Article : Google Scholar : PubMed/NCBI

27 

Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, Shyr Y, Matrisian LM, Carbone DP and Lin PC: Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell. 6:409–421. 2004. View Article : Google Scholar : PubMed/NCBI

28 

Nefedova Y, Fishman M, Sherman S, Wang X, Beg AA and Gabrilovich DI: Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. Cancer Res. 67:11021–11028. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Talmadge JE and Gabrilovich DI: History of myeloid-derived suppressor cells. Nat Rev Cancer. 13:739–752. 2013. View Article : Google Scholar : PubMed/NCBI

30 

Kotsakis A, Harasymczuk M, Schilling B, Georgoulias V, Argiris A and Whiteside TL: Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples. J Immunol Methods. 381:14–22. 2012. View Article : Google Scholar : PubMed/NCBI

31 

Gehad AE, Lichtman MK, Schmults CD, Teague JE, Calarese AW, Jiang Y, Watanabe R and Clark RA: Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas. J Invest Dermatol. 132:2642–2651. 2012. View Article : Google Scholar : PubMed/NCBI

32 

Mendoza AE, Neely CJ, Charles AG, Kartchner LB, Brickey WJ, Khoury AL, Sempowski GD, Ting JP, Cairns BA and Maile R: Radiation combined with thermal injury induces immature myeloid cells. Shock. 38:532–542. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Marhaba R, Vitacolonna M, Hildebrand D, Baniyash M, Freyschmidt-Paul P and Zöller M: The importance of myeloid-derived suppressor cells in the regulation of autoimmune effector cells by a chronic contact eczema. J Immunol. 179:5071–5081. 2007. View Article : Google Scholar : PubMed/NCBI

34 

Skabytska Y, Wolbing F, Günther C, Köberle M, Kaesler S, Chen KM, Guenova E, Demircioglu D, Kempf WE, Volz T, et al: Cutaneous innate immune sensing of Toll-like receptor 2–6 ligands suppresses T cell immunity by inducing myeloid-derived suppressor cells. Immunity. 41:762–775. 2014. View Article : Google Scholar : PubMed/NCBI

35 

Guan Q, Moreno S, Qing G, Weiss CR, Lu L, Bernstein CN, Warrington RJ, Ma Y and Peng Z: The role and potential therapeutic application of myeloid-derived suppressor cells in TNBS-induced colitis. J Leukoc Biol. 94:803–811. 2013. View Article : Google Scholar : PubMed/NCBI

36 

Smith AR and Reynolds JM: Editorial: The contribution of myeloid-derived suppression to inflammatory disease. J Leukoc Biol. 96:361–364. 2014. View Article : Google Scholar : PubMed/NCBI

37 

Mizutani H, Ohmoto Y, Mizutani T, Murata M and Shimizu M: Role of increased production of monocytes TNF-alpha, IL-1beta and IL-6 in psoriasis: Relation to focal infection, disease activity and responses to treatments. J Dermatol Sci. 14:145–153. 1997. View Article : Google Scholar : PubMed/NCBI

38 

Okubo Y and Koga M: Peripheral blood monocytes in psoriatic patients overproduce cytokines. J Dermatol Sci. 17:223–232. 1998. View Article : Google Scholar : PubMed/NCBI

39 

Melani C, Sangaletti S, Barazzetta FM, Werb Z and Colombo MP: Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res. 67:11438–11446. 2007. View Article : Google Scholar : PubMed/NCBI

40 

Ilkovitch D and Lopez DM: Immune modulation by melanoma-derived factors. Exp Dermatol. 17:977–985. 2008. View Article : Google Scholar : PubMed/NCBI

41 

Chen HW, Chen HY, Wang LT, Wang FH, Fang LW, Lai HY, Chen HH, Lu J, Hung MS, Cheng Y, et al: Mesenchymal stem cells tune the development of monocyte-derived dendritic cells toward a myeloid-derived suppressive phenotype through growth-regulated oncogene chemokines. J Immunol. 190:5065–5077. 2013. View Article : Google Scholar : PubMed/NCBI

42 

Mehra VC, Ramgolam VS and Bender JR: Cytokines and cardiovascular disease. J Leukoc Biol. 78:805–818. 2005. View Article : Google Scholar : PubMed/NCBI

43 

Wang YG, Xiong X, Chen ZY, Liu KL, Yang JH, Wen Q, Wu FQ, Hu XF, Peng YD, Wu JJ, et al: Expansion of myeloid-derived suppressor cells in patients with acute coronary syndrome. Cell Physiol Biochem. 35:292–304. 2015. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Ilkovitch D and Ferris LK: Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules. Mol Med Rep 14: 3935-3940, 2016.
APA
Ilkovitch, D., & Ferris, L.K. (2016). Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules. Molecular Medicine Reports, 14, 3935-3940. https://doi.org/10.3892/mmr.2016.5685
MLA
Ilkovitch, D., Ferris, L. K."Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules". Molecular Medicine Reports 14.4 (2016): 3935-3940.
Chicago
Ilkovitch, D., Ferris, L. K."Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules". Molecular Medicine Reports 14, no. 4 (2016): 3935-3940. https://doi.org/10.3892/mmr.2016.5685
Copy and paste a formatted citation
x
Spandidos Publications style
Ilkovitch D and Ferris LK: Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules. Mol Med Rep 14: 3935-3940, 2016.
APA
Ilkovitch, D., & Ferris, L.K. (2016). Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules. Molecular Medicine Reports, 14, 3935-3940. https://doi.org/10.3892/mmr.2016.5685
MLA
Ilkovitch, D., Ferris, L. K."Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules". Molecular Medicine Reports 14.4 (2016): 3935-3940.
Chicago
Ilkovitch, D., Ferris, L. K."Myeloid-derived suppressor cells are elevated in patients with psoriasis and produce various molecules". Molecular Medicine Reports 14, no. 4 (2016): 3935-3940. https://doi.org/10.3892/mmr.2016.5685
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