|
1
|
Hostetter TH: Progression of renal disease
and renal hypertrophy. Annu Rev Physiol. 57:263–278. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Al-Douahji M, Brugarolas J, Brown PA,
Stehman-Breen CO, Alpers CE and Shankland SJ: The cyclin kinase
inhibitor p21WAF/CIP1 is required for glomerular hypertrophy in
experimental diabetic nephropathy. Kidney Int. 56:1691–1699. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Bleich D, Chen S, Zipser B, Sun D, Funk CD
and Nadler JL: Resistance to the type 1 diabetes induction in
12-lipoxygenase knockout mice. J Clin Invest. 103:1431–1436. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Yuan H, Lanting L, Xu ZG, Li SL, Swiderski
P, Putta S, Jonnalagadda M, Kato M and Natarajan R: Effects of
cholesterol tagged small interfering RNA targeting
12/15-lipoxygenase on parameters of diabetic nephropathy in mouse
model of type 1 diabetes. Am J Physiol Renal Physiol.
295:F605–F617. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ma J, Natarajan R, LaPage J, Lanting L,
Kim N, Becerra D, Clemmons B, Nast CC, Surya Prakash GK, Mandal M
and Adler SG: 12/15-lipoxygenase inhibitors in diabetic nephropathy
in the rat. Prostaglandins Leukot Essent Fatty Acids. 72:13–20.
2005. View Article : Google Scholar
|
|
6
|
Kim YS, Xu ZG, Reddy MA, Li SL, Lanting L,
Sharma K, Adler SG and Natarajan R: Novel interactions between
TGF-{beta}1 actions and the 12/15-lipoxygenase pathway in mesangial
cells. J Am Soc Nephrol. 16:352–362. 2005. View Article : Google Scholar
|
|
7
|
Kato M and Natarajan R: Diabetic
nephropathy-emerging epigenetic mechanisms. Nat Rev Nephrol.
10:517–530. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Reddy MA, Tak Park J and Natarajan R:
Epigenetic modifications in the pathogenesis of diabetic
nephropathy. Semin Nephrol. 33:341–353. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Reddy MA, Sumanth P, Lanting L, Yuan H,
Wang M, Mar D, Alpers CE, Bomsztyk K and Natarajan R: Losartan
reverses permissive epigenetic changes in renal glomeruli of
diabetic db/db mice. Kidney Int. 85:362–373. 2014. View Article : Google Scholar :
|
|
10
|
Natarajan R: Drugs targeting epigenetic
histone acetylation in vascular smooth muscle cells for restenosis
and atherosclerosis. Arterioscler Thromb Vasc Biol. 31:725–727.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yuan H, Reddy MA, Sun G, Lanting L, Wang
M, Kato M and Natarajan R: Involvement of p300/CBP and epigenetic
histone acetylation in TGF-β1-mediated gene transcription in
mesangial cells. Am J Physiol Renal Physiol. 304:F601–F613. 2013.
View Article : Google Scholar
|
|
12
|
Kato M, Dang V, Wang M, Park JT, Deshpande
S, Kadam S, Mardiros A, Zhan Y, Oettgen P, Putta S, et al: TGF-β
induces acetylation of chromatin and of Ets-1 to alleviate
repression of miR-192 in diabetic nephropathy. Sci Signal.
6:ra432013. View Article : Google Scholar
|
|
13
|
Sun G, Reddy MA, Yuan H, Lanting L, Kato M
and Natarajan R: Epigenetic histone methylation modulates fibrotic
gene expression. J Am Soc Nephrol. 21:2069–2080. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Villeneuve LM and Natarajan R: The role of
epigenetics in the pathology of diabetic complications. Am J
Physiol Renal Physiol. 299:F14–F25. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Reddy MA, Zhang E and Natarajan R:
Epigenetic mechanisms in diabetic complications and metabolic
memory. Diabetologia. 58:443–455. 2015. View Article : Google Scholar :
|
|
16
|
Miao F, Chen Z, Genuth S, Paterson A,
Zhang L, Wu X, Li SM, Cleary P, Riggs A, Harlan DM, et al:
Evaluating the role of epigenetic histone modifications in the
metabolic memory of type 1 diabetes. Diabetes. 63:1748–1762. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ling C and Groop L: Epigenetics: A
molecular link between environmental factors and type 2 diabetes.
Diabetes. 58:2718–2725. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Pirola L, Balcerczyk A, Okabe J and
El-Osta A: Epigenetic phenomena linked to diabetic complications.
Nat Rev Endocrinol. 6:665–675. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Marmorstein R and Trievel RC: Histone
modifying enzymes: Structures, mechanisms, and specificities.
Biochim Biophys Acta. 1789:58–68. 2009. View Article : Google Scholar
|
|
20
|
Shilatifard A: Chromatin modifications by
methylation and ubiquitination: Implications in the regulation of
gene expression. Annu Rev Biochem. 75:243–269. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Sun G, Reddy MA, Yuan H, Lanting L, Kato M
and Natarajan R: Epigenetic histone methylation modulates fibrotic
gene expression. J Am Soc Nephrol. 21:2069–2080. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Reed SM and Quelle DE: p53 Acetylation:
Regulation and consequences. Cancers (Basel). 7:30–69. 2014.
View Article : Google Scholar
|
|
23
|
Marouco D, Garabadgiu AV, Melino G and
Barlev NA: Lysine-specific modifications of p53: A matter of life
and death? Oncotarget. 4:1556–1571. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lee JT and Gu W: SIRT1: Regulator of p53
deacetylation. Genes Cancer. 4:112–117. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Shi Y, Sawada J, Sui G, Affar el B,
Whetstine JR, Lan F, Ogawa H, Luke MP, Nakatani Y and Shi Y:
Coordinated histone modifications mediated by a CtBP co-repressor
complex. Nature. 422:735–738. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Shi Y, Lan F, Matson C, Mulligan P,
Whetstine JR, Cole PA, Casero RA and Shi Y: Histone demethylation
mediated by the nuclear amine oxidase homolog LSD1. Cell.
119:941–953. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Wang H, Cao R, Xia L, Erdjument-Bromage H,
Borchers C, Tempst P and Zhang Y: Purification and functional
characterization of a histone H3-lysine 4-specific
methyltransferase. Mol Cell. 8:1207–1217. 2001. View Article : Google Scholar
|
|
28
|
Nishioka K, Chuikov S, Sarma K,
Erdjument-Bromage H, Allis CD, Tempst P and Reinberg D: Set9, a
novel histone H3 methyltransferase that facilitates transcription
by precluding histone tail modifications required for
heterochromatin formation. Genes Dev. 16:479–489. 2002. View Article : Google Scholar : PubMed/NCBI
|
