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Article

Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray

  • Authors:
    • Jinshan Zhao
    • Hegang Li
    • Kaidong Liu
    • Baoxun Zhang
    • Peipei Li
    • Jianning He
    • Ming Cheng
    • Wei De
    • Jifeng Liu
    • Yaofeng Zhao
    • Lihua Yang
    • Nan Liu
  • View Affiliations / Copyright

    Affiliations: College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, Shandong 266109, P.R. China, Department of Reproduction and Breeding, Qingdao Institute of Animal Science and Veterinary Medicine, Qingdao, Shandong 266100, P.R. China, College of Basic Medicine, Nanjing Medical University, Nanjing, Jiangsu 210002, P.R. China, College of Biology, China Agricultural University, Beijing 100193, P.R. China, College of Biotechnology, Inner Mongolia Agricultural University, Hohhot, Nei Mongol Autonomous Region 010018, P.R. China
  • Pages: 3823-3831
    |
    Published online on: September 6, 2016
       https://doi.org/10.3892/mmr.2016.5728
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Abstract

Goats are an important source of fibers. In the present study microarray technology was used to investigate the potential genes primarily involved in hair and cashmere growth in the Laiwu black goat. A total of 655 genes differentially expressed in body (hair‑growing) and groin (hairless) skin were identified, and their potential association with hair and cashmere growth was analyzed. The majority of genes associated with hair growth regulation could be assigned to intracellular, intracellular organelle, membrane‑bound vesicle, cytoplasmic vesicle, pattern binding, heparin binding, polysaccharide binding, glycosaminoglycan binding and cytoplasmic membrane‑bound vesicle categories. Numerous genes upregulated in body compared with groin skin contained common motifs for nuclear factor 1A, Yi, E2 factor (E2F) and cyclic adenosine monophosphate response element binding (CREB)/CREBβ binding sites in their promoter region. The promoter region of certain genes downregulated in body compared with groin skin contained three common regions with LF‑A1, Yi, E2F, Collier/Olfactory‑1/early B‑cell factor 1, peroxisome proliferator‑activated receptor α or U sites. Thus, the present study identified molecules in the cashmere‑bearing skin area of the Laiwu black goat, which may contribute to hair and cashmere traits.
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Spandidos Publications style
Zhao J, Li H, Liu K, Zhang B, Li P, He J, Cheng M, De W, Liu J, Zhao Y, Zhao Y, et al: Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray. Mol Med Rep 14: 3823-3831, 2016.
APA
Zhao, J., Li, H., Liu, K., Zhang, B., Li, P., He, J. ... Liu, N. (2016). Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray. Molecular Medicine Reports, 14, 3823-3831. https://doi.org/10.3892/mmr.2016.5728
MLA
Zhao, J., Li, H., Liu, K., Zhang, B., Li, P., He, J., Cheng, M., De, W., Liu, J., Zhao, Y., Yang, L., Liu, N."Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray". Molecular Medicine Reports 14.4 (2016): 3823-3831.
Chicago
Zhao, J., Li, H., Liu, K., Zhang, B., Li, P., He, J., Cheng, M., De, W., Liu, J., Zhao, Y., Yang, L., Liu, N."Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray". Molecular Medicine Reports 14, no. 4 (2016): 3823-3831. https://doi.org/10.3892/mmr.2016.5728
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Spandidos Publications style
Zhao J, Li H, Liu K, Zhang B, Li P, He J, Cheng M, De W, Liu J, Zhao Y, Zhao Y, et al: Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray. Mol Med Rep 14: 3823-3831, 2016.
APA
Zhao, J., Li, H., Liu, K., Zhang, B., Li, P., He, J. ... Liu, N. (2016). Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray. Molecular Medicine Reports, 14, 3823-3831. https://doi.org/10.3892/mmr.2016.5728
MLA
Zhao, J., Li, H., Liu, K., Zhang, B., Li, P., He, J., Cheng, M., De, W., Liu, J., Zhao, Y., Yang, L., Liu, N."Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray". Molecular Medicine Reports 14.4 (2016): 3823-3831.
Chicago
Zhao, J., Li, H., Liu, K., Zhang, B., Li, P., He, J., Cheng, M., De, W., Liu, J., Zhao, Y., Yang, L., Liu, N."Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray". Molecular Medicine Reports 14, no. 4 (2016): 3823-3831. https://doi.org/10.3892/mmr.2016.5728
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