|
1
|
Jacobs JJ, Kieboom K, Marino S, DePinho RA
and van Lohuizen M: The oncogene and Polycomb-group gene bmi-1
regulates cell proliferation and senescence through the ink4a
locus. Nature. 397:164–168. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wong KY, Yim RL, Kwong YL, Leung CY, Hui
PK, Cheung F, Liang R, Jin DY and Chim CS: Epigenetic inactivation
of the MIR129-2 in hematological malignancies. J Hematol Oncol.
6:162013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Park IK, Qian D, Kiel M, Becker MW,
Pihalja M, Weissman IL, Morrison SJ and Clarke MF: Bmi-1 is
required for maintenance of adult self-renewing haematopoietic stem
cells. Nature. 423:302–305. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Molofsky AV, He S, Bydon M, Morrison SJ
and Pardal R: Bmi-1 promotes neural stem cell self-renewal and
neural development but not mouse growth and survival by repressing
the p16Ink4a and p19Arf senescence pathways. Genes Dev.
19:1432–1437. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yang J, Chai L, Liu F, Fink LM, Lin P,
Silberstein LE, Amin HM, Ward DC and Ma Y: Bmi-1 is a target gene
for SALL4 in hematopoietic and leukemic cells. Proc Natl Acad Sci
USA. 104:10494–10499. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kim JH, Yoon SY, Kim CN, Joo JH, Moon SK,
Choe IS, Choe YK and Kim JW: The Bmi-1 oncoprotein is overexpressed
in human colorectal cancer and correlates with the reduced
p16INK4a/p14ARF proteins. Cancer Lett. 203:217–224. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Larmonie NS, Dik WA, Beverloo HB, van
Wering ER, van Dongen JJ and Langerak AW: BMI1 as oncogenic
candidate in a novel TCRB-associated chromosomal aberration in a
patient with TCRgammadelta+ T-cell acute lymphoblastic leukemia.
Leukemia. 22:1266–1267. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Vonlanthen S, Heighway J, Altermatt HJ,
Gugger M, Kappeler A, Borner MM, van Lohuizen M and Betticher DC:
The bmi-1 oncoprotein is differentially expressed in non-small cell
lung cancer and correlates with INK4A-ARF locus expression. Br J
Cancer. 84:1372–1376. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jagani Z, Wiederschain D, Loo A, He D,
Mosher R, Fordjour P, Monahan J, Morrissey M, Yao YM, Lengauer C,
et al: The Polycomb group protein Bmi-1 is essential for the growth
of multiple myeloma cells. Cancer Res. 70:5528–5538. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wu SQ, Xu ZZ, Niu WY, Huang HB and Zhan R:
ShRNA-mediated Bmi-1 silencing sensitizes multiple myeloma cells to
bortezomib. Int J Mol Med. 34:616–623. 2014.PubMed/NCBI
|
|
11
|
Bhattacharya R, Nicoloso M, Arvizo R, Wang
E, Cortez A, Rossi S, Calin GA and Mukherjee P: MiR-15a and MiR-16
control Bmi-1 expression in ovarian cancer. Cancer Res.
69:9090–9095. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Godlewski J, Nowicki MO, Bronisz A,
Williams S, Otsuki A, Nuovo G, Raychaudhury A, Newton HB, Chiocca
EA and Lawler S: Targeting of the Bmi-1 oncogene/stem cell renewal
factor by microRNA-128 inhibits glioma proliferation and
self-renewal. Cancer Res. 68:9125–9130. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
He X, Dong Y, Wu CW, Zhao Z, Ng SS, Chan
FK, Sung JJ and Yu J: MicroRNA-218 inhibits cell cycle progression
and promotes apoptosis in colon cancer by downregulating BMI1
polycomb ring finger oncogene. Mol Med. 18:1491–1498.
2013.PubMed/NCBI
|
|
14
|
Yu X, Jiang X, Li H, Guo L, Jiang W and Lu
SH: miR-203 inhibits the proliferation and self-renewal of
esophageal cancer stem-like cells by suppressing stem renewal
factor Bmi-1. Stem Cells Dev. 23:576–585. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chen CZ: MicroRNAs as oncogenes and tumor
suppressors. N Engl J Med. 353:1768–1771. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bartel DP: MicroRNAs: Target recognition
and regulatory functions. Cell. 136:215–233. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lujambio A and Esteller M: CpG island
hypermethylation of tumor suppressor microRNAs in human cancer.
Cell Cycle. 6:1455–1459. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Bueno MJ, Pérez de Castro I, Gómez de
Cedrón M, Santos J, Calin GA, Cigudosa JC, Croce CM,
Fernández-Piqueras J and Malumbres M: Genetic and epigenetic
silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene
expression. Cancer Cell. 13:496–506. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Furuta M, Kozaki KI, Tanaka S, Arii S,
Imoto I and Inazawa J: miR-124 and miR-203 are epigenetically
silenced tumor-suppressive microRNAs in hepatocellular carcinoma.
Carcinogenesis. 31:766–776. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wong KY, Liang R, So CC, Jin DY, Costello
JF and Chim CS: Epigenetic silencing of MIR203 in multiple myeloma.
Br J Haematol. 154:569–578. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Berezikov E, Guryev V, van de Belt J,
Wienholds E, Plasterk RH and Cuppen E: Phylogenetic shadowing and
computational identification of human microRNA genes. Cell.
120:21–24. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
International Myeloma Working Group, .
Criteria for the classification of monoclonal gammopathies,
multiple myeloma and related disorders: A report of the
International Myeloma Working Group. Br J Haematol. 121:749–757.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Song W, Tao K, Li H, Jin C, Song Z, Li J,
Shi H, Li X, Dang Z and Dou K: Bmi-1 is related to proliferation,
survival and poor prognosis in pancreatic cancer. Cancer Sci.
101:1754–1760. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Choi YJ, Choi YL, Cho EY, Shin YK, Sung
KW, Hwang YK, Lee SJ, Kong G, Lee JE, Kim JS, et al: Expression of
Bmi-1 protein in tumor tissues is associated with favorable
prognosis in breast cancer patients. Breast Cancer Res Treat.
113:83–93. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
van Leenders GJ, Dukers D, Hessels D, van
den Kieboom SW, Hulsbergen CA, Witjes JA, Otte AP, Meijer CJ and
Raaphorst FM: Polycomb-group oncogenes EZH2, BMI1, and RING1 are
overexpressed in prostate cancer with adverse pathologic and
clinical features. Eur Urol. 52:455–463. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
