|
1
|
Kaufmann KB, Büning H, Galy A, Schambach A
and Grez M: Gene therapy on the move. EMBO Mol Med. 5:1642–1661.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wilson JM: Gendicine: The first commercial
gene therapy product. Hum Gene Ther. 16:1014–1015. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cronin M, Stanton R, Francis K and Tangney
M: Bacterial vectors for imaging and cancer gene therapy: A review.
Cancer Gene Ther. 19:731–740. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lam P, Khan G, Stripecke R, Hui K,
Kasahara N, Peng K and Guinn B: The innovative evolution of cancer
gene and cellular therapies. Cancer Gene Ther. 20:141–149. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Jessup M, Greenberg B, Mancini D, Cappola
T, Pauly DF, Jaski B, Yaroshinsky A, Zsebo KM, Dittrich H and
Hajjar RJ: Calcium Upregulation by Percutaneous Administration of
Gene Therapy in Cardiac Disease (CUPID) Investigators: Calcium
upregulation by percutaneous administration of gene therapy in
cardiac disease (CUPID): A phase 2 trial of intracoronary gene
therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with
advanced heart failure. Circulation. 124:304–313. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
LeWitt PA, Rezai AR, Leehey MA, Ojemann
SG, Flaherty AW, Eskandar EN, Kostyk SK, Thomas K, Sarkar A,
Siddiqui MS, et al: AAV2-GAD gene therapy for advanced Parkinson's
disease: A double-blind, sham-surgery controlled, randomised trial.
Lancet Neurol. 10:309–319. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Elsner M, Terbish T, Jörns A, Naujok O,
Wedekind D, Hedrich HJ and Lenzen S: Reversal of diabetes through
gene therapy of diabetic rats by hepatic insulin expression via
lentiviral transduction. Mol Ther. 20:918–926. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Herrera-Carrillo E and Berkhout B: Bone
marrow gene therapy for HIV/AIDS. Viruses. 7:3910–3936. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Tian K, Qi M, Wang L, Li Z, Xu J, Li Y,
Liu G, Wang B, Huard J and Li G: Two-stage therapeutic utility of
ectopically formed bone tissue in skeletal muscle induced by
adeno-associated virus containing bone morphogenetic protein-4
gene. J Orthop Surg Res. 10:862015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tseng SS, Lee MA and Reddi AH: Nonunions
and the potential of stem cells in fracture-healing. J Bone Joint
Surg Am. 1(90): Suppl. S92–S98. 2008. View Article : Google Scholar
|
|
11
|
Wang Y, Zeng B and Li X: Expression of
human calcitonin by microencapsulated recombinant myoblasts.
Biotechnol Lett. 28:1453–89. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Johnsen SA, Subramaniam M, Katagiri T,
Janknecht R and Spelsberg TC: Transcriptional regulation of Smad2
is required for enhancement of TGFbeta/Smad signaling by TGFbeta
inducible early gene. J Cell Biochem. 87:233–241. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kobayashi T, Liu X, Wen FQ, Kohyama T,
Shen L, Wang XQ, Hashimoto M, Mao L, Togo S, Kawasaki S, et al:
Smad3 mediates TGF-beta1-induced collagen gel contraction by human
lung fibroblasts. Biochem Biophys Res Commun. 339:290–295. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Guo L, Zhao RC and Wu Y: The role of
microRNAs in self-renewal and differentiation of mesenchymal stem
cells. Exp Hematol. 39:608–616. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wang EA, Rosen V, D'Alessandro JS, Bauduy
M, Cordes P, Harada T, Israel DI, Hewick RM, Kerns KM and LaPan P:
Recombinant human bone morphogenetic protein induces bone
formation. Proc Natl Acad Sci USA. 87:2220–2224. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Hay E, Hott M, Graulet AM, Lomri A and
Marie PJ: Effects of bone morphogenetic protein-2 on human neonatal
calvaria cell differentiation. J Cell Biochem. 72:81–93. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Noshi T, Yoshikawa T, Dohi Y, Ikeuchi M,
Horiuchi K, Ichijima K, Sugimura M, Yonemasu K and Ohgushi H:
Recombinant human bone morphogenetic protein-2 potentiates the in
vivo osteogenic ability of marrow/hydroxyapatite composites. Artif
Organs. 25:201–208. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wilson JM: Adenoviruses as gene-delivery
vehicles. N Engl J Med. 334:1185–1187. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Laurencin CT, Attawia MA, Lu LQ, Borden
MD, Lu HH, Gorum WJ and Lieberman JR: Poly
(lactide-co-glycolide)/hydroxyapatite delivery of BMP-2-producing
cells: A regional gene therapy approach to bone regeneration.
Biomaterials. 22:1271–1277. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Huang Z, Ren PG, Ma T, Smith RL and
Goodman SB: Modulating osteogenesis of mesenchymal stem cells by
modifying growth factor availability. Cytokine. 51:305–10. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cohen MM Jr: Bone morphogenetic proteins
with some comments on fibrodysplasia ossificans progressiva and
NOGGIN. Am J Med Genet. 109:87–92. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Guo Q, Liu C, Li J, Zhu C, Yang H and Li
B: Gene expression modulation in TGF-β3-mediated rabbit bone marrow
stem cells using electrospun scaffolds of various stiffness. J Cell
Mol Med. 19:1582–1592. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hara ES, Ono M, Pham HT, Sonoyama W,
Kubota S, Kubota S, Takigawa M, Matsumoto T, Young MF, Olsen BR and
Kuboki T: Fluocinolone acetonide Is a potent synergistic factor of
TGF-β3-associated chondrogenesis of bone marrow-derived mesenchymal
stem cells for articular surface regeneration. J Bone Miner Res.
30:1585–1596. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Eduardo K, Hong L and Mao JJ: Inhibition
of osteogenic differentiation of human mesenchymal stem cells.
Wound Repair Regen. 15:413–9421. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Shi Y and Massagué J: Mechanisms of
TGF-beta signaling from cell membrane to the nucleus. Cell.
113:685–700. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Moioli EK, Hong L, Guardado J, Clark PA
and Mao JJ: Sustained Release of TGFbeta3 from PLGA microspheres
and its effect on early osteogenic differentiation of human
mesenchymal stem cells tissue eng. 12:537–546. 2006.PubMed/NCBI
|
|
27
|
Li F and Niyibizi C: Cells derived from
murine induced pluripotent stem cells (iPSC) by treatment with
members of TGF-beta family give rise to osteoblasts differentiation
and form bone in vivo. BMC Cell Biol. 13:352012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Klar RM, Duarte R, Dix-Peek T and
Ripamonti U: The induction of bone formation by the recombinant
human transforming growth factor-β3. Biomaterials. 35:2773–2788.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Haschtmann D, Ferguson SJ and Stoyanov JV:
BMP-2 and TGF-β3 do not prevent spontaneous degeneration in rabbit
disc explants but induce ossification of the annulus fibrosus. Eur
Spine J. 21:1724–1733. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
He T, Wang Y, Xiang J and Zhang H: In vivo
tracking of novel SPIO-Molday ION rhodamine-B™-labeled human bone
marrow-derived mesenchymal stem cells after lentivirus-mediated
COX-2 silencing: A preliminary study. Curr Gene Ther. 14:136–145.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Alhadlaq A and Mao JJ: Mesenchymal stem
cells: Isolation and therapeutics. Stem Cells Dev. 13:436–448.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Parekkadan B and Milwid JM: Mesenchymal
stem cells as therapeutics. Annu Rev Biomed Eng. 12:87–1174. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Bianco P, Riminucci M, Gronthos S and
Robey PG: Bone marrow stromal stem cells: Nature, biology, and
potential applications. Stem Cells. 19:180–192. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Derubeis AR and Cancedda R: Bone marrow
stromal cells (BMSCs) in bone engineering: Limitations and recent
advances. Ann. Biomed. Eng. 32:160–165. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM and
Long F: Sequential roles of hedgehog and wnt signaling in
osteoblast development. Development. 132:49–60. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Forriol F and Shapiro F: Bone development:
Interaction of molecular components and biophysical forces. Clin
Orthop Relat Res. 432:14–33. 2005. View Article : Google Scholar
|
|
37
|
Gordon KJ and Blobe GC: Role of
transforming growth factor-beta superfamily signaling pathways in
human disease. Biochim Biophys Acta. 1782:197–228. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Herpin A, Lelong C and Favrel P:
Transforming growth factor-beta-related proteins: An ancestral and
widespread superfamily of cytokines in metazoans. Dev Comp Immunol.
28:461–485. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Assoian RK, Komoriya A, Meyers CA, Miller
DM and Sporn MB: Transforming growth factor-beta in human
platelets. Identification of a major storage site, purification and
characterization. J Biol Chem. 258:7155–7160. 1983.PubMed/NCBI
|
|
40
|
Ripamonti U: Soluble osteogenic molecular
signals and the induction of bone formation. Biomaterials.
27:807–822. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Carreira AC, Lojudice FH, Halcsik E,
Navarro RD, Sogayar MC and Granjeiro JM: Bone morphogenetic
proteins: Facts, challenges, and future perspectives. J Dent Res.
93:335–345. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Burkus JK, Sandhu HS, Gornet MF and
Longley MC: Use of rhBMP-2 in combination with structural cortical
allografts: Clinical and radiographic outcomes in anterior lumbar
spinal surgery. J Bone Joint Surg Am. 87:1205–1212. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Meisel HJ, Schnöring M, Hohaus C, Minkus
Y, Beier A, Ganey T and Mansmann U: Posterior lumbar interbody
fusion using rhBMP-2. Eur Spine J. 17:1735–1744. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Rahman MS, Akhtar N, Jamil HM, Banik RS
and Asaduzzaman SM: TGF-b/BMP signaling and other molecular events:
Regulation of osteoblastogenesis and bone formation. Bone Research.
3:150052015. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
ten Dijke P, Miyazono K and Heldin CH:
Signaling inputs converge on nuclear effectors in TGF-beta
signaling. Trends Biochem Sci. 25:64–70. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Kusanagi K, Inoue H, Ishidou Y, Mishima
HK, Kawabata M and Miyazono K: Characterization of a bone
morphogenetic protein-responsive Smad-binding element. Mol Biol
Cell. 11:555–565. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Toom A, Arend A, Gunnarsson D, Ulfsparre
R, Suutre S, Haviko T and Selstam G: Bone formation zones in
heterotopic ossifications: Histologic findings and increased
expression of bonemorphogenetic protein 2 and transforming growth
factors beta2 and beta3. Calcif Tissue Int. 80:259–267. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Oest ME, Dupont KM, Kong HJ, Mooney DJ and
Guldberg RE: Quantitative assessment of scaffold and growth
factor-mediated repair of critically sized bone defects. J Orthop
Res. 25:941–950. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Cheah FS, Winkler C, Jabs EW and Chong SS:
Tgfbeta3 regulation of chondrogenesis and osteogenesis in zebrafish
is mediated through formation and survival of a subpopulation of
the cranial neural crest. Mech Dev. 127:329–344. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Kovacevic D, Fox JA, Bedi A, Ying L, Deng
XH, Warren RF and Rodeo AS: Calcium-phosphate matrix with or
without TGF-β3 improves tendon-bone healing after rotator cuff
repair. Am J Sports Med. 39:811–819. 2011. View Article : Google Scholar : PubMed/NCBI
|
