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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2016 Volume 14 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Post-translational modifications of FOXO family proteins (Review)

Ziyao Wang, Tinghe Yu, Ping Huang
Pages: 4931-4941
Published online on: 20 October 2016

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Review Open Access

miRNAs and their role in the correlation between schizophrenia and cancer (Review)

E. Rizos, N. Siafakas, E. Skourti, C. Papageorgiou, J. Tsoporis, T. H. Parker, D. I. Christodoulou, D. A. Spandidos, E. Katsantoni, V. Zoumpourlis
Pages: 4942-4946
Published online on: 14 October 2016

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Article Open Access

Rho kinase II interference by small hairpin RNA ameliorates 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine‑induced parkinsonism in mice

Qiong Zhang, Yong‑Fei Zhao, Jian‑Ying Xi, Wen‑Bo Yu, Bao‑Guo Xiao
Pages: 4947-4956
Published online on: 26 October 2016

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Article Open Access

Rapamycin inhibits lipopolysaccharide-induced neuroinflammation in vitro and in vivo

Na‑Shun Mengke, Bei Hu, Qian‑Peng Han, Yi‑Yu Deng, Ming Fang, Di Xie, Ang Li, Hong‑Ke Zeng
Pages: 4957-4966
Published online on: 25 October 2016

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Article Open Access

Changes in enteroendocrine and immune cells following colitis induction by TNBS in rats

Magdy El‑Salhy, Jan Gunnar Hatlebakk
Pages: 4967-4974
Published online on: 31 October 2016

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Article Open Access

The impact of Wnt signalling and hypoxia on osteogenic and cementogenic differentiation in human periodontal ligament cells

Shuigen Li, Jin Shao, Yinghong Zhou, Thor Friis, Jiangwu Yao, Bin Shi, Yin Xiao
Pages: 4975-4982
Published online on: 31 October 2016

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Article Open Access

Tanshinone II A stabilizes vulnerable plaques by suppressing RAGE signaling and NF-κB activation in apolipoprotein-E-deficient mice Retraction in /10.3892/mmr.2024.13410

Dong Zhao, Lufang Tong, Lixin Zhang, Hong Li, Yingxin Wan, Tiezhong Zhang
Pages: 4983-4990
Published online on: 01 November 2016

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Article Open Access

Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics

Jun Shao, Wei Fan, Biao Ma, Yiping Wu
Pages: 4991-4998
Published online on: 27 October 2016

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Article Open Access

Identification of HLA‑A*1101‑restricted cytotoxic T lymphocyte epitopes derived from epidermal growth factor pathway substrate number 8

Huifang Lu, Baishan Tang, Yanjie He, Weijun Zhou, Jielei Qiu, Yuhua Li
Pages: 4999-5006
Published online on: 25 October 2016

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Article Open Access

Transcription factor NF‑YA promotes a malignant phenotype by upregulating fatty acid synthase expression

Jing Guo, Ling Min Kong, Ai Fen Peng, Xin Hua Long, Yang Zhou, Yong Shu
Pages: 5007-5014
Published online on: 27 October 2016

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Article Open Access

Aberrant expression of B7‑H4 may contribute to the development of hepatocellular carcinoma

Lingling Yuan, Lijie Dong, Guohua Yu, Wanfeng Fan, Lin Zhang, Peiyuan Wang, Xuemei Hu, Mingdong Zhao
Pages: 5015-5024
Published online on: 25 October 2016

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Article Open Access

miR-129 predicts prognosis and inhibits cell growth in human prostate carcinoma

Song Xu, Xiao‑Ming Yi, Zheng‑Yu Zhang, Jing‑Ping Ge, Wen‑Quan Zhou
Pages: 5025-5032
Published online on: 19 October 2016

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Article Open Access

NFAT5 participates in seawater inhalation‑induced acute lung injury via modulation of NF-κB activity

Congcong Li, Manling Liu, Liyan Bo, Wei Liu, Qingqing Liu, Xiangjun Chen, Dunquan Xu, Zhichao Li, Faguang Jin
Pages: 5033-5040
Published online on: 19 October 2016

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Article Open Access

Identification of potential biomarkers and drugs for papillary thyroid cancer based on gene expression profile analysis

Ting Qu, Yan‑Ping Li, Xiao‑Hong Li, Yan Chen
Pages: 5041-5048
Published online on: 19 October 2016

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Article Open Access

miR‑34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3

Wu Xiang, Haotian Lin, Qilin Wang, Wan Chen, Zhaochuan Liu, Hui Chen, Hui Zhang, Weirong Chen
Pages: 5049-5056
Published online on: 27 October 2016

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Article Open Access

Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration

Sha Li, Bin Zhou, Ben Liu, Yaou Zhou, Huali Zhang, Tong Li, Xiaoxia Zuo
Pages: 5057-5064
Published online on: 31 October 2016

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Article Open Access

Notch1 is associated with the differentiation of human bone marrow‑derived mesenchymal stem cells to cardiomyocytes

Zipu Yu, Yu Zou, Jingya Fan, Chengchen Li, Liang Ma
Pages: 5065-5071
Published online on: 19 October 2016

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Article Open Access

Systemic symptoms in irritable bowel syndrome: An investigative study on the role of enterocyte disintegrity, endotoxemia and inflammation

Ragnhild Undseth, Arnold Berstad, Jørgen Valeur
Pages: 5072-5076
Published online on: 21 October 2016

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Article Open Access

Whole-exome sequencing identification of novel DNAH5 mutations in a young patient with primary ciliary dyskinesia

Gen Kano, Hisashi Tsujii, Kazuhiko Takeuchi, Kaname Nakatani, Makoto Ikejiri, Satoru Ogawa, Hisami Kubo, Mizuho Nagao, Takao Fujisawa
Pages: 5077-5083
Published online on: 21 October 2016

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Article Open Access

Mechanical stretch regulates microRNA expression profile via NF-κB activation in C2C12 myoblasts

Wenxi Hua, Mahui Zhang, Yongkui Wang, Lei Yu, Tingting Zhao, Xiaozhong Qiu, Leyu Wang
Pages: 5084-5092
Published online on: 31 October 2016

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Article Open Access

Systematic analysis of mRNA expression profiles in NSCLC cell lines to screen metastasis-related genes

Ying Liu, Lei Liu, Tao Yu, He‑Chun Lin, Dandan Chu, Wei Deng, Ming‑Xia Yan, Jing Li, Ming Yao
Pages: 5093-5103
Published online on: 01 November 2016

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Article Open Access

mRNA expression of delta-HER2 and its clinicopathological correlation in HER2-overexpressing breast cancer

Ryuichi Wada, Soroku Yagihashi, Zenya Naito
Pages: 5104-5110
Published online on: 26 October 2016

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Article Open Access

ATP5B and ETFB metabolic markers in children with congenital hydronephrosis

Qi Zhao, Yi Yang, Changlin Wang, Ying Hou, Hui Chen
Pages: 5111-5115
Published online on: 01 November 2016

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Article Open Access

Effects of the IGF-1/PTEN/Akt/FoxO signaling pathway on male reproduction in rats subjected to water immersion and restraint stress

Pan Huang, Zhengrong Zhou, Fangxiong Shi, Genbao Shao, Ran Wang, Jintian Wang, Kangxin Wang, Wei Ding
Pages: 5116-5124
Published online on: 24 October 2016

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Article Open Access

Effects of inactivated Enterococcus faecalis on the proliferation and osteogenic induction of osteoblasts

Zhongchun Tong, Jinglei Ma, Jiali Tan, Lijia Huang, Junqi Ling
Pages: 5125-5133
Published online on: 26 October 2016

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Article Open Access

Chromosome 10q26 deletion syndrome: Two new cases and a review of the literature

Shaobin Lin, Yi Zhou, Qun Fang, Jianzhu Wu, Zhiqiang Zhang, Yuanjun Ji, Yanmin Luo
Pages: 5134-5140
Published online on: 19 October 2016

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Article Open Access

Suppressive effects of Gua Lou Gui Zhi decoction on MCAO-induced NO and PGE2 production are dependent on the MAPK and NF-κB signaling pathways

Haixia Hu, Xiaoqin Zhu, Ruhui Lin, Zuanfang Li, Lidian Chen
Pages: 5141-5147
Published online on: 21 October 2016

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Article Open Access

Inhibitory effects of dieckol on hypoxia-induced epithelial-mesenchymal transition of HT29 human colorectal cancer cells

Seung‑Hyun Jeong, You‑Jin Jeon, Sun Joo Park
Pages: 5148-5154
Published online on: 21 October 2016

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Article Open Access

Extracts containing CLPs of Bacillus amyloliquefaciens JN68 isolated from chicken intestines exert antimicrobial effects, particularly on methicillin-resistant Staphylococcus aureus and Listeria monocytogenes

Jen‑Ni Chen, Chyou‑Wei Wei, Hsiao‑Chun Liu, Shu‑Ying Chen, Chinshuh Chen, Yu‑Min Juang, Chien‑Chen Lai, Giou‑Teng Yiang
Pages: 5155-5163
Published online on: 27 October 2016

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Article Open Access

Combined antitumor activity of the nitroreductase/CB1954 suicide gene system and γ-rays in HeLa cells in vitro

Geling Teng, Yuanrong Ju, Yepeng Yang, Hu Hua, Jingyu Chi, Xiuan Mu
Pages: 5164-5170
Published online on: 01 November 2016

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Article Open Access

Expression and correlation of NRF2, KEAP1, NQO-1 and HO-1 in advanced squamous cell carcinoma of the larynx and their association with clinicopathologic features

Changjiang Li, Haitao Wu, Shuyi Wang, Jiaxing Zhu
Pages: 5171-5179
Published online on: 01 November 2016

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Article Open Access

Combined application of Rho-ROCKII and GSK-3β inhibitors exerts an improved protective effect on axonal regeneration in rats with spinal cord injury

Ge Zhang, Fei Lei, Qingzhong Zhou, Daxiong Feng, Yongheng Bai
Pages: 5180-5188
Published online on: 01 November 2016

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Article

SLC25A13 cDNA cloning analysis using peripheral blood lymphocytes facilitates the identification of a large deletion mutation: Molecular diagnosis of an infant with neonatal intrahepatic cholestasis caused by citrin deficiency

Han‑Shi Zeng, Wei‑Xia Lin, Shu‑Tao Zhao, Zhan‑Hui Zhang, Heng‑Wen Yang, Feng‑Ping Chen, Yuan‑Zong Song, Zhi‑Nan Yin
Pages: 5189-5194
Published online on: 21 October 2016

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Article

A novel blood-pooling MR contrast agent: Carboxymethyl-diethylaminoethyl dextran magnetite

Akinaga Sonoda, Norihisa Nitta, Keiko Tsuchiya, Ayumi Nitta‑Seko, Shinichi Ohta, Hideji Otani, Kiyoshi Murata
Pages: 5195-5198
Published online on: 21 October 2016

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Article

Knockdown of macrophage inhibitory cytokine-1 in RPMI-8226 human multiple myeloma cells inhibits osteoclastic differentiation through inhibiting the RANKL-Erk1/2 signaling pathway

Mingzhou Yuan, Junmin Chen, Zhiyong Zeng
Pages: 5199-5204
Published online on: 24 October 2016

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Article

PACE4 regulates apoptosis in human pancreatic cancer Panc‑1 cells via the mitochondrial signaling pathway

Xiao‑Feng Tian, Guo‑Min Huang, Hong‑Liang Zang, Hong Cao
Pages: 5205-5210
Published online on: 25 October 2016

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Article

Alterations in ACE and ABCG2 expression levels in the testes of rats subjected to atropine-induced toxicity

Xue‑Fang Li, Quan‑Yong Huang, Wen‑Zhong Yang, Hui‑Jie Wang, Can‑Wei Li
Pages: 5211-5216
Published online on: 19 October 2016

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Article

Recombinant human soluble thrombomodulin protects against brain injury in a CVST rat model, via downregulation of the HMGB1-RAGE axis

Jian‑Jun Gu, Jie‑Bin Chen, Jian‑He Zhang, Hao Zhang, Shou‑Sen Wang
Pages: 5217-5222
Published online on: 26 October 2016

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Article

Microfloral diversity in the lower respiratory tracts of neonates with bacterial infectious pneumonia combined with ventilator‑associated pneumonia

Wei Lu, Jia‑Lin Yu, Lu‑Quan Li, Qi Lu, Zheng‑Li Wang, Yun Pan
Pages: 5223-5230
Published online on: 25 October 2016

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Article

Resveratrol induces cell cycle arrest and apoptosis in human eosinophils from asthmatic individuals

Xin Hu, Jing Wang, Yu Xia, Mihereguli Simayi, Syed Ikramullah, Yuanbing He, Shihong Cui, Shuang Li, Qimanguli Wushouer
Pages: 5231-5236
Published online on: 25 October 2016

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Article

Peptide mimics of a carbohydrate‑associated epitope expressed by cancer cells: Identification of vaccine candidates

Liyan Wen, Sha Yang, Ping Zhu, Yingxin Yu, Xiaoyan Qiu, Ning Fu, Yanjun Liu
Pages: 5237-5244
Published online on: 19 October 2016

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Article

Effect of zinc deficiency on mouse renal interstitial fibrosis in diabetic nephropathy

Xiuli Zhang, Dan Liang, Xu Lian, Zhi‑Hong Chi, Xuemei Wang, Yue Zhao, Zhang Ping
Pages: 5245-5252
Published online on: 20 October 2016

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Article

HEB silencing induces anti-proliferative effects on U87MG cells cultured as neurospheres and monolayers

Paulo R. D. V. Godoy, Ana Paula L. Montaldi, Elza T. Sakamoto‑Hojo
Pages: 5253-5260
Published online on: 21 October 2016

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Article

The Hedgehog signaling pathway is associated with poor prognosis in breast cancer patients with the CD44+/CD24‑ phenotype

Haishan Zhao, Hongtao Tang, Qinghuan Xiao, Miao He, Lin Zhao, Yingzi Fu, Huizhe Wu, Zhaojin Yu, Qian Jiang, Yuanyuan Yan, Feng Jin, Minjie Wei
Pages: 5261-5270
Published online on: 19 October 2016

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Article

Glucocorticoid receptor contributes to the altered expression of hepatic cytochrome P450 upon cigarette smoking

Xue Li, Zhongfang Yan, Qi Wu, Xin Sun, Fan Li, Subei Zhang, Kuan Li, Li Li, Junping Wu, Long Xu, Jing Feng, Wen Ning, Zhixue Liu, Huaiyong Chen
Pages: 5271-5280
Published online on: 27 October 2016

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Article

Lipopolysaccharide-induced cytokine expression pattern in peripheral blood mononuclear cells in childhood obesity

Yu Wu, Bin Yue, Jia Liu
Pages: 5281-5287
Published online on: 20 October 2016

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Article

Long non-coding RNA RP5-833A20.1 inhibits proliferation, metastasis and cell cycle progression by suppressing the expression of NFIA in U251 cells

Chun‑Min Kang, Yan‑Wei Hu, Ying Nie, Jia‑Yi Zhao, Shu‑Fen Li, Shuai Chu, Hai‑Xia Li, Qing‑Shui Huang, Yu‑Rong Qiu
Pages: 5288-5296
Published online on: 19 October 2016

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Article

Resveratrol alleviates sepsis‑induced myocardial injury in rats by suppressing neutrophil accumulation, the induction of TNF‑α and myocardial apoptosis via activation of Sirt1

Rui An, Lei Zhao, Jian Xu, Cong Xi, Haixun Li, Guohong Shen, Wei Zhang, Shumiao Zhang, Lijun Sun
Pages: 5297-5303
Published online on: 19 October 2016

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Article

Mitochondrial transcription factor A contributes to cisplatin resistance in patients with estrogen receptor‑positive breast cancer

Wei Gao, Mei‑Hong Wu, Ning Wang, Ming‑Zheng Ying, Ying‑Yi Zhang, Jing Hua, Liu Chuan, Ya‑Jie Wang
Pages: 5304-5310
Published online on: 25 October 2016

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Article

Long non‑coding RNA AK055347 is upregulated in patients with atrial fibrillation and regulates mitochondrial energy production in myocardiocytes

Guiying Chen, Hong Guo, Ying Song, Huiying Chang, Shaojun Wang, Miaomiao Zhang, Chang Liu
Pages: 5311-5317
Published online on: 26 October 2016

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Article

Identification of serum miRNAs differentially expressed in human epilepsy at seizure onset and post-seizure

Jijun Sun, Weidong Cheng, Lifeng Liu, Shuxin Tao, Zhangyong Xia, Lifeng Qi, Min Huang
Pages: 5318-5324
Published online on: 31 October 2016

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Article

Daidzein impairs Leydig cell testosterone production and Sertoli cell function in neonatal mouse testes: An in vitro study

Yanfeng Zhu, Hua Xu, Min Li, Zhibin Gao, Jie Huang, Linxi Liu, Xiaoming Huang, Yun Li
Pages: 5325-5333
Published online on: 26 October 2016

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Article

Simvastatin exerts anti-hepatitis B virus activity by inhibiting expression of minichromosome maintenance protein 7 in HepG2.2.15 cells

Wenjie Li, Fei Cao, Juan Li, Zhixin Wang, Yu Ren, Zheyong Liang, Peijun Liu
Pages: 5334-5342
Published online on: 20 October 2016

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Article

Inhalation of inactivated‑Mycobacterium phlei prevents asthma‑mediated airway hyperresponsiveness and airway eosinophilia in mice by reducing IL‑5 and IL‑13 levels

Moyu Ming, Zhixi Luo, Shengqiu Lv, Chaoqian Li
Pages: 5343-5349
Published online on: 19 October 2016

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Article

Depletion of complement system immunity in patients with myocardial infarction

Wenwen Yan, Lin Che, Jinfa Jiang, Fan Yang, Qianglin Duan, Haoming Song, Xiaohong Liu, Yuqin Shen, Lemin Wang
Pages: 5350-5356
Published online on: 01 November 2016

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Article

Effective treatment of polydatin weakens the symptoms of collagen-induced arthritis in mice through its anti-oxidative and anti-inflammatory effects and the activation of MMP-9

Bo Li, Xiao‑Li Wang
Pages: 5357-5362
Published online on: 31 October 2016

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Article

Effects of celastrol on enhancing apoptosis of ovarian cancer cells via the downregulation of microRNA‑21 and the suppression of the PI3K/Akt‑NF‑κB signaling pathway in an in vitro model of ovarian carcinoma

Haiyan Zhang, Jianhua Li, Guang Li, Surong Wang
Pages: 5363-5368
Published online on: 26 October 2016

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Article

PA-MSHA inhibits proliferation and induces apoptosis in human non-small cell lung cancer cell lines with different genotypes

Xinmin Zhao, Xianghua Wu, Wen Yu, Xuwei Cai, Qi Liu, Xiaolong Fu, Zhebin Liu, Dali Hu, Shiyun Pan, Qiling Huang
Pages: 5369-5376
Published online on: 20 October 2016

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Article

Mechanisms underlying the antiapoptotic and anti-inflammatory effects of monotropein in hydrogen peroxide-treated osteoblasts

Fang‑Bing Zhu, Jian‑Yue Wang, Ying‑Liang Zhang, Yun‑Gen Hu, Zhen‑Shuang Yue, Lin‑Ru Zeng, Wen‑Jie Zheng, Qiao Hou, Shi‑Gui Yan, Ren‑Fu Quan
Pages: 5377-5384
Published online on: 31 October 2016

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Article

Antihypertensive therapy improves insulin resistance and serum levels of interleukin-6 and -10 in spontaneously hypertensive rats with steatohepatitis

Masaya Kozono, Hirofumi Uto, Rie Ibusuki, Shiho Arima, Kohei Oda, Hiroki Taguchi, Fumisato Sasaki, Yuichiro Nasu, Shinichi Hashimoto, Hitoshi Setoyama, Shuji Kanmura, Masatsugu Numata, Hirohito Tsubouchi, Akio Ido
Pages: 5385-5394
Published online on: 21 October 2016

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Article

Tristetraprolin regulates the decay of the hypoxia-induced vascular endothelial growth factor mRNA in ARPE-19 cells

Jinhyun Ryu, Hyemin Seong, Nal Ae Yoon, Seong Wook Seo, Jeong Woo Park, Sang Soo Kang, Jong Moon Park, Yong Seop Han
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Published online on: 26 October 2016

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Association between the angiotensin converting enzyme gene insertion/deletion polymorphism and metabolic disturbances in women with polycystic ovary syndrome

Katarzyna Ożegowska, Anna Bogacz, Joanna Bartkowiak‑Wieczorek, Agnieszka Seremak‑Mrozikiewicz, Leszek Pawelczyk
Pages: 5401-5407
Published online on: 31 October 2016

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Article

Nobiletin ameliorates isoflurane-induced cognitive impairment via antioxidant, anti-inflammatory and anti-apoptotic effects in aging rats

Junying Bi, Haiyan Zhang, Jing Lu, Weifu Lei
Pages: 5408-5414
Published online on: 01 November 2016

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Article

microRNA-361 targets Wilms' tumor 1 to inhibit the growth, migration and invasion of non-small-cell lung cancer cells

Shuxiang Yang, Yingchao Zhang, Xin Zhao, Jingzheng Wang, Jianjing Shang
Pages: 5415-5421
Published online on: 19 October 2016

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Association of SCNN1B promoter methylation with essential hypertension

Qilong Zhong, Chunyan Liu, Rui Fan, Shiwei Duan, Xuting Xu, Jinshun Zhao, Shuqi Mao, Wen Zhu, Lingmei Hao, Fengying Yin, Lina Zhang
Pages: 5422-5428
Published online on: 31 October 2016

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Correction Open Access

[Corrigendum] Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis

Chao Huang, Hong Liu, Xiuli Gong, Bin Wen, Dan Chen, Jinyuan Liu, Fengliang Hu
Pages: 5429-5429
Published online on: 25 October 2016

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Correction Open Access

[Corrigendum] Integration of gene expression and DNA methylation profiles provides a molecular subtype for risk assessment in atherosclerosis

Sheng‑Chao Ma, Hui‑Ping Zhang, Fan‑Qi Kong, Hui Zhang, Cheng Yang, Yang‑Yang He, Yan‑Hua Wang, An‑Ning Yang, Ju Tian, Xiao‑Ling Yang, Ming‑Hao Zhang, Hua Xu, Yi‑Deng Jiang, Zheng Yu
Pages: 5430-5430
Published online on: 01 November 2016

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A mutation in β-amyloid precursor protein renders SH‑SY5Y cells vulnerable to isoflurane toxicity: The role of inositol 1,4,5‑trisphosphate receptors

Xiang Liu, Shan Song, Qiujun Wang, Tianbao Yuan, Jihua He
Pages: 5435-5442
Published online on: 08 November 2016

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Rapid and sensitive detection of Plesiomonas shigelloides by cross‑priming amplification of the hugA gene

Shuang Meng, Yi Wang, Yan Wang, Changyun Ye
Pages: 5443-5450
Published online on: 14 November 2016

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Identfication of key miRNAs in pancreatitis using bioinformatics analysis of microarray data

Dadong Wang, Zi‑Man Zhu, Yu‑Liang Tu, Chun‑Qing Dou, Yong Xu, Xiang‑Long Tan, Ming‑Ming Han, Zhuang‑Jie Yang, Xin Jin, Bao Zhang, Shouwang Cai, Zhi‑Wei Liu
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Published online on: 07 November 2016

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Presence of multimeric isoforms of human C-reactive protein in tissues and blood

Qiling Li, Wei Xu, Xue Xue, Qi Wang, Lu Han, Wenzhi Li, Shulan Lv, Dong Liu, Jendai Richards, Zhujun Shen, Li Ma, Qing Song
Pages: 5461-5466
Published online on: 03 November 2016

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Alteration of histone H3 lysine 9 dimethylation in peripheral white blood cells of septic patients with trauma and cancer

Linghui Jiang, Yiqin Wang, Duming Zhu, Zhanggang Xue, Hailei Mao
Pages: 5467-5474
Published online on: 22 November 2016

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Roles of mitochondrial transcription factor A and microRNA‑590‑3p in the development of colon cancer

Kaiming Wu, Zhenxian Zhao, Yinglian Xiao, Jianjun Peng, Jianhui Chen, Yulong He
Pages: 5475-5480
Published online on: 21 November 2016

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Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury

Youguang Gao, Ting Chen, Xianghui Lei, Yunfeng Li, Xingui Dai, Yuanyuan Cao, Qionglei Ding, Xiabao Lei, Tao Li, Xianzhong Lin
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Published online on: 11 November 2016

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Hydroxyproline-containing collagen peptide derived from the skin of the Alaska pollack inhibits HIV-1 infection

In Seung Jang, Sun Joo Park
Pages: 5489-5494
Published online on: 16 November 2016

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NLS‑RARα modulates acute promyelocytic leukemia NB4 cell proliferation and differentiation via the PI3K/AKT pathway

Hao Song, Liu Li, Liang Zhong, Rong Yang, Kailing Jiang, Xiaoqun Yang, Beizhong Liu
Pages: 5495-5500
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Age-dependent endocrine disorders involved in the pathogenesis of refractory acne in women

Simona Ianoşi, Gabriel Ianoşi, Daniela Neagoe, Oana Ionescu, Ovidiu Zlatian, Anca Oana Docea, Corin Badiu, Maria Sifaki, Dimitris Tsoukalas, Aristidis M. Tsatsakis, Demetrios A. Spandidos, Daniela Călina
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Expression pattern of HMGB1 and its association with autophagy in acute necrotizing pancreatitis

Can Yu, Xiao Yu, Hong‑Wei Zhu, Xia Li, Li‑Hua Huang, Zhi‑Qiang Li, Duo Han, Hui Huang
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Published online on: 15 November 2016

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Synergistic effects of overexpression of BMP‑2 and TGF‑β3 on osteogenic differentiation of bone marrow mesenchymal stem cells

Yilin Wang, Tian He, Jie Liu, Hongzhi Liu, Lugang Zhou, Wei Hao, Yujie Sun, Xin Wang
Pages: 5514-5520
Published online on: 22 November 2016

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Inhibition of the growth of human melanoma cells by methionine enkephalin

Dong‑Mei Wang, Guang‑Chuan Wang, Jing Yang, Nicolas P. Plotnikoff, Noreen Griffin, Yu‑Man Han, Rui‑Qun Qi, Xing‑Hua Gao, Feng‑Ping Shan
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Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR‑γ/HO‑1 pathways

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Published online on: 07 November 2016

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LRG1 promotes angiogenesis through upregulating the TGF‑β1 pathway in ischemic rat brain

Hongmei Meng, Yuejia Song, Jiyuan Zhu, Qi Liu, Pengtian Lu, Na Ye, Zhen Zhang, Yuxin Pang, Jiping Qi, He Wu
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SirT1 activator represses the transcription of TNF‑α in THP‑1 cells of a sepsis model via deacetylation of H4K16

Guo‑Dong Chen, Wei‑Dong Yu, Xiao‑Ping Chen
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Published online on: 15 November 2016

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Method for in vitro differentiation of bone marrow mesenchymal stem cells into endothelial progenitor cells and vascular endothelial cells

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Pages: 5551-5555
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Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury Retraction in /10.3892/mmr.2017.6299

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Pages: 5556-5566
Published online on: 18 November 2016

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Article

Melatonin attenuates TGFβ1-induced epithelial-mesenchymal transition in lung alveolar epithelial cells

Na Yu, Yi‑Tian Sun, Xin‑Ming Su, Miao He, Bing Dai, Jian Kang
Pages: 5567-5572
Published online on: 16 November 2016

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RNA‑seq profiling of mRNA associated with hypertrophic cardiomyopathy

Chang‑Wei Ren, Jia‑Ji Liu, Jin‑Hua Li, Jing‑Wei Li, Jiang Dai, Yong‑Qiang Lai
Pages: 5573-5586
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Identification of suitable reference genes for BDV-infected primary rat hippocampal neurons

Qiang Mao, Lujun Zhang, Yujie Guo, Lu Sun, Siwen Liu, Peng He, Rongzhong Huang, Lin Sun, Shigang Chen, Hong Zhang, Peng Xie
Pages: 5587-5594
Published online on: 22 November 2016

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Nobiletin attenuates lipopolysaccharide/D‑galactosamine‑induced liver injury in mice by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF‑κB‑mediated cytokine production

Zhenxing He, Xuanfei Li, Hao Chen, Kun He, Yiming Liu, Junhua Gong, Jianping Gong
Pages: 5595-5600
Published online on: 15 November 2016

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Crocus sativus L. protects against SDS‑induced intestinal damage and extends lifespan in Drosophila melanogaster

Zonglin Liu, Yuchen Chen, Hong Zhang, Li Hua Jin
Pages: 5601-5606
Published online on: 15 November 2016

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Article

Neuroprotective effects of vitexin against isoflurane-induced neurotoxicity by targeting the TRPV1 and NR2B signaling pathways

Linlin Chen, Bin Zhang, Shiqiang Shan, Xin Zhao
Pages: 5607-5613
Published online on: 16 November 2016

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Cantharidin induces G2/M arrest and triggers apoptosis in renal cell carcinoma

Yu Ren, Shu‑Wei Zhang, Zhen‑Hua Xie, Xiao‑Ming Xu, Liang‑Liang Chen, Zhong‑Guan Lou, Guo‑Bin Weng, Xu‑Ping Yao
Pages: 5614-5618
Published online on: 23 November 2016

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Effects of hyperbaric oxygen therapy on RAGE and MCP-1 expression in rats with spinal cord injury

Yong Wang, Chunsheng Li, Chunjin Gao, Zhuo Li, Jing Yang, Xuehua Liu, Fang Liang
Pages: 5619-5625
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Dec1 expression predicts prognosis and the response to temozolomide chemotherapy in patients with glioma

Xiao‑Ming Li, Wei Lin, Jiang Wang, Wei Zhang, An‑An Yin, Yi Huang, Jian Zhang, Libo Yao, Huan Bian, Jing Zhang, Xiang Zhang
Pages: 5626-5636
Published online on: 03 November 2016

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GRIN3A and MAPT stimulate nerve overgrowth in macrodactyly

Xu Shi, Lu Lu, Xiu Jin, Bin Liu, Xiguang Sun, Laijin Lu, Yanfang Jiang
Pages: 5637-5643
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Article

Distribution, pharmacokinetics and primary metabolism model of tramadol in zebrafish

Huiqin Zhuo, Hongwei Jin, Huifang Peng, Heqing Huang
Pages: 5644-5652
Published online on: 21 November 2016

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Stanniocalcin 2 improved osteoblast differentiation via phosphorylation of ERK

Juan Zhou, Yinghua Li, Lina Yang, Yougen Wu, Yunjiao Zhou, Yunqing Cui, Gong Yang, Yang Hong
Pages: 5653-5659
Published online on: 16 November 2016

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Zoledronic acid overcomes adriamycin resistance in acute myeloid leukemia cells by promoting apoptosis

Rui‑Fang Fan, Yu‑Xin Chen, Zhi‑Gang Fang, Xiao‑Yan Guo, Ying Lu, Ling‑Ling Liu, Yi‑Chuan Xu, Xiang‑Fu Liu, Dong‑Jun Lin
Pages: 5660-5666
Published online on: 21 November 2016

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Effect of ximenynic acid on cell cycle arrest and apoptosis and COX-1 in HepG2 cells

Fang Cai, Jianying Li, Yandi Liu, Zunyi Zhang, D. S. Hettiarachchi, Duo Li
Pages: 5667-5676
Published online on: 03 November 2016

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Estrogen is neuroprotective against hypoglycemic injury in murine N38 hypothalamic cells

Tandra R. Chakraborty, Joshua Cohen, Darien Yohanan, Eilliut Alicea, Benjamin S. Weeks, Sanjoy Chakraborty
Pages: 5677-5684
Published online on: 18 November 2016

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Article

Effects of interleukin-1 receptor-associated kinase 1 RNA interference in dendritic cells on inflammatory cytokine release and T-cell proliferation

Yan Gao, Xuxu Xu, Juan Feng, Ying Ma, Dongming Zheng, Yiming Meng, Fengping Shan
Pages: 5685-5692
Published online on: 15 November 2016

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Article

Hsa‑miR‑371‑5p inhibits human mesangial cell proliferation and promotes apoptosis in lupus nephritis by directly targeting hypoxia‑inducible factor 1α

Feifei Yao, Liqiu Sun, Wei Fang, Huamin Wang, Dongsheng Yao, Rui Cui, Jia Xu, Li Wang, Xiumei Wang
Pages: 5693-5698
Published online on: 14 November 2016

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Article

PI3K/Akt signaling is involved in the pathogenesis of bleomycin‑induced pulmonary fibrosis via regulation of epithelial‑mesenchymal transition

Xiao‑Ling Zhang, Rong‑Ge Xing, Liang Chen, Chun‑Rong Liu, Zhi‑Gang Miao
Pages: 5699-5706
Published online on: 22 November 2016

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Obesity‑associated miR‑148a is regulated by cytokines and adipokines via a transcriptional mechanism

Chunmei Shi, Lingxia Pang, Chenbo Ji, Jiaqin Wang, Ning Lin, Jiantao Chen, Ling Chen, Lei Yang, Fangyan Huang, Yahui Zhou, Xirong Guo, Hui Liang, Min Zhang
Pages: 5707-5712
Published online on: 14 November 2016

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Role of perivascular adipose tissue in nicotine‑induced endothelial cell inflammatory responses

Chao‑Nan Wang, Gen‑Huan Yang, Zhan‑Qi Wang, Chang‑Wei Liu, Tian‑Jia Li, Zhi‑Chao Lai, Shi‑Ying Miao, Lin‑Fang Wang, Bao Liu
Pages: 5713-5718
Published online on: 09 November 2016

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Article

Etiopathogenesis of adolescent idiopathic scoliosis: Expression of melatonin receptors 1A/1B, calmodulin and estrogen receptor 2 in deep paravertebral muscles revisited

Josef Zamecnik, Lenka Krskova, Jaromir Hacek, Ivana Stetkarova, Martin Krbec
Pages: 5719-5724
Published online on: 07 November 2016

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Article

Selection of suitable reference genes for gene expression studies in normal human ovarian tissues, borderline ovarian tumours and ovarian cancer

Olumide Ofinran, Ujjal Bose, Daniel Hay, Summi Abdul, Cristina Tufatelli, Raheela Khan
Pages: 5725-5731
Published online on: 08 November 2016

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Article

Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells

Yingge Wang, Shan Gao, Weiguang Wang, Jingyan Liang
Pages: 5732-5738
Published online on: 23 November 2016

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Alteration of epoxyeicosatrienoic acids in the liver and kidney of cytochrome P450 4F2 transgenic mice

Bijun Zhang, Guangrui Lai, Xiaoliang Liu, Yanyan Zhao
Pages: 5739-5745
Published online on: 23 November 2016

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MicroRNA‑93 is overexpressed and induces apoptosis in glaucoma trabecular meshwork cells

Yansa Wang, Fenghua Li, Shuyun Wang
Pages: 5746-5750
Published online on: 14 November 2016

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Post‑translational modification of CREB‑1 decreases collagen I expression by inhibiting the TGF‑β1 signaling pathway in rat hepatic stellate cells

Xiaoling Deng, Liang Deng, Pei Wang, Chunwei Cheng, Keshu Xu
Pages: 5751-5759
Published online on: 07 November 2016

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Article

Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats

Yu Zhang, Ruo‑Meng Li, Chun Wang, Na Liu, Shen Lv, Jun‑Yu Xiong
Pages: 5760-5766
Published online on: 16 November 2016

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Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
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Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
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Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
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Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Review Open Access

Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Article Open Access

Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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Review Open Access

R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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