|
1
|
Newman JR, Connolly TM, Illing EA, Kilgore
ML, Locher JL and Carroll WR: Survival trends in Hypopharyngeal
cancer: A population-based review. Laryngoscope. 125:624–629. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Berrino F and Gatta G: Variation in
survival of patients with head and neck cancer in Europe by the
site of origin of the tumours. EUROCARE working group. Eur J
Cancer. 34:2154–2161. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Li X, Liu X, Wang J, Wang Z, Jiang W, Reed
E, Zhang Y, Liu Y and Li QQ: Thalidomide down-regulates the
expression of VEGF and bFGF in cisplatin-resistant human lung
carcinoma cells. Anticancer Res. 23:2481–2487. 2003.PubMed/NCBI
|
|
4
|
Folkman J: Angiogenesis in cancer,
vascular, rheumatoid and other disease. Nat Med. 1:27–31. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Carmeliet P and Jain RK: Angiogenesis in
cancer and other diseases. Nature. 407:249–257. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ferrara N: VEGF and the quest for tumour
angiogenesis factors. Nat Rev Cancer. 2:795–803. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ferrara N, Gerber HP and LeCouter J: The
biology of VEGF and its receptors. Nat Med. 9:669–676. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Su JL, Yen CJ, Chen PS, Chuang SE, Hong
CC, Kuo IH, Chen HY, Hung MC and Kuo ML: The role of the
VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer. 96:541–545.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Plate K: From angiogenesis to
lymphangiogenesis. Nat Med. 7:151–152. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Olsson AK, Dimberg A, Kreuger J and
Claesson-Welsh L: VEGF receptor signalling - in control of vascular
function. Nat Rev Mol Cell Biol. 7:359–371. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Fuentes JJ, Genescà L, Kingsbury TJ,
Cunningham KW, Pérez-Riba M, Estivill X and de la Luna S: DSCR1,
overexpressed in Down syndrome, is an inhibitor of
calcineurin-mediated signaling pathways. Hum Mol Genet.
9:1681–1690. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Harris CD, Ermak G and Davies KJ: Multiple
roles of the DSCR1 (Adapt78 or RCAN1) gene and its protein product
calcipressin 1 (or RCAN1) in disease. Cell Mol Life Sci.
62:2477–2486. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hesser BA, Liang XH, Camenisch G, Yang S,
Lewin DA, Scheller R, Ferrara N and Gerber HP: Down syndrome
critical region protein 1 (DSCR1), a novel VEGF target gene that
regulates expression of inflammatory markers on activated
endothelial cells. Blood. 104:149–158. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Aynaci FM, Orhan F, Celep F and Karagüzel
A: Frequency of cardiovascular and gastrointestinal malformations,
leukemia and hypothyroidism in children with Down syndrome in
Trabzon, Turkey. Turk J Pediatr. 40:103–109. 1998.PubMed/NCBI
|
|
15
|
Rothermel B, Vega RB, Yang J, Wu H,
Bassel-Duby R and Williams RS: A protein encoded within the Down
syndrome critical region is enriched in striated muscles and
inhibits calcineurin signaling. J Biol Chem. 275:8719–8725. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Vega RB, Rothermel BA, Weinheimer CJ,
Kovacs A, Naseem RH, Bassel-Duby R, Williams RS and Olson EN: Dual
roles of modulatory calcineurin-interacting protein 1 in cardiac
hypertrophy. Proc Natl Acad Sci USA. 100:669–674. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Iizuka M, Abe M, Shiiba K, Sasaki I and
Sato Y: Down syndrome candidate region 1, a downstream target of
VEGF, participates in endothelial cell migration and angiogenesis.
J Vasc Res. 41:334–344. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Yao YG and Duh EJ: VEGF selectively
induces Down syndrome critical region 1 gene expression in
endothelial cells: A mechanism for feedback regulation of
angiogenesis? Biochem Biophys Res Commun. 321:648–656. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Suzuki K, Nishimi D, Yagishita T, Takanami
M and Hiruta N: Testicular tumor in Down syndrome. Int J Urol.
12:925–927. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Satgé D, Sommelet D, Geneix A, Nishi M,
Malet P and Vekemans M: A tumor profile in Down syndrome. Am J Med
Genet. 78:207–216. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Patja K, Pukkala E, Sund R, Iivanainen M
and Kaski M: Cancer incidence of persons with Down syndrome in
Finland: A population-based study. Int J Cancer. 118:1769–1772.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Baek KH, Zaslavsky A, Lynch RC, Britt C,
Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, et al:
Down's syndrome suppression of tumour growth and the role of the
calcineurin inhibitor DSCR1. Nature. 459:1126–1130. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Sussan TE, Yang A, Li F, Ostrowski MC and
Reeves RH: Trisomy represses Apc (Min)-mediated tumours in mouse
models of Down's syndrome. Nature. 451:73–75. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lu C, Pan X, Gao J and Li Z: Study of
expression and significance of DSCR1 gene in laryngopharynx cancer
and peri-cancerous tissues. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke
Za Zhi. 25:848–850. 2011.(In Chinese). PubMed/NCBI
|
|
25
|
Liu D, Jia H, Holmes DI, Stannard A and
Zachary I: Vascular endothelial growth factor-regulated gene
expression in endothelial cells: KDR-mediated induction of Egr3 and
the related nuclear receptors Nur77, Nurr1 and Nor1. Arterioscler
Thromb Vasc Biol. 23:2002–2007. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Abe M and Sato Y: CDNA microarray analysis
of the gene expression profile of VEGF-activated human umbilical
vein endothelial cells. Angiogenesis. 4:289–298. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
World Medical Association: World Medical
Association Declaration of Helsinki, . Ethical principles for
medical research involving human subjects. JAMA. 310:2191–2194.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Sobin L and Wittekind C: UICC TNM
classification of malignant tumours. 5th. Wiley Liss; New York, NY:
pp. 1381997
|
|
29
|
Ryeom S, Baek KH, Rioth MJ, Lynch RC,
Zaslavsky A, Birsner A, Yoon SS and McKeon F: Targeted deletion of
the calcineurin inhibitor DSCR1 suppresses tumor growth. Cancer
Cell. 13:420–431. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bunone G, Vigneri P, Mariani L, Butó S,
Collini P, Pilotti S, Pierotti MA and Bongarzone I: Expression of
angiogenesis stimulators and inhibitors in human thyroid tumors and
correlation with clinical pathological features. Am J Pathol.
155:1967–1976. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Yonemura Y, Fushida S, Bando E, Kinoshita
K, Miwa K, Endo Y, Sugiyama K, Partanen T, Yamamoto H and Sasaki T:
Lymphangiogenesis and the vascular endothelial growth factor
receptor (VEGFR)-3 in gastric cancer. Eur J Cancer. 37:918–923.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Pan MG, Xiong Y and Chen F: NFAT gene
family in inflammation and cancer. Curr Mol Med. 13:543–554. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Kroll J and Waltenberger J: The vascular
endothelial growth factor receptor KDR activates multiple signal
transduction pathways in porcine aortic endothelial cells. J Biol
Chem. 272:32521–32527. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Rousseau S, Houle F, Landry J and Huot J:
p38 MAP kinase activation by vascular endothelial growth factor
mediates actin reorganization and cell migration in human
endothelial cells. Oncogene. 15:2169–2177. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Gerber HP, McMurtrey A, Kowalski J, Yan M,
Keyt BA, Dixit V and Ferrara N: Vascular endothelial growth factor
regulates endothelial cell survival through the
phosphatidylinositol 3′-kinase/Akt signal transduction pathway.
Requirement for Flk-1/KDR activation. J Biol Chem. 273:30336–30343.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Takahashi T, Ueno H and Shibuya M: VEGF
activates protein kinase C-dependent, but Ras-independent
Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial
cells. Oncogene. 18:2221–2230. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kingsbury TJ and Cunningham KW: A
conserved family of calcineurin regulators. Genes Dev.
14:1595–1604. 2000.PubMed/NCBI
|
|
38
|
Chan B, Greenan G, McKeon F and
Ellenberger T: Identification of a peptide fragment of DSCR1 that
competitively inhibits calcineurin activity in vitro and in vivo.
Proc Natl Acad Sci USA. 102:13075–13080. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Pinchai N, Perfect BZ, Juvvadi PR,
Fortwendel JR, Cramer RA Jr, Asfaw YG, Heitman J, Perfect JR and
Steinbach WJ: Aspergillus fumigatus calcipressin CbpA is involved
in hyphal growth and calcium homeostasis. Eukaryot Cell. 8:511–519.
2009. View Article : Google Scholar : PubMed/NCBI
|
