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Article

Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides

  • Authors:
    • Venerando Rapisarda
    • Caterina Ledda
    • Serena Matera
    • Lucrezia Fago
    • Giorgio Arrabito
    • Luca Falzone
    • Andrea Marconi
    • Massimo Libra
    • Carla Loreto
  • View Affiliations / Copyright

    Affiliations: Section of Occupational Medicine, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy, Prevention and Safety in the Workplace Service, Provincial Health Agency of Ragusa, Ragusa, Italy, Section of General and Clinical Pathology and Oncology, Department of Biomedical and Biotechnology Sciences, University of Catania, Catania, Italy, Section of Human Anatomy and Histology, Department of Biomedical and Biotechnology Sciences, University of Catania, Catania, Italy
  • Pages: 3379-3382
    |
    Published online on: March 24, 2017
       https://doi.org/10.3892/mmr.2017.6385
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Abstract

Exposure to pesticides represents a potential health risk for the general population and for agricultural workers in particular. Some researchers observed that occupational exposure to pesticides is associated with risk of non‑Hodgkin's lymphoma (NHL). The chromosomal translocation t(14;18)(q32;q21) is one of the most common chromosomal abnormalities in NHL. The aim of this study was to detect the effects of pesticides on t(14;18) chromosome translocation in agricultural workers after short-term exposure. Fifty-two workers occupationally exposed to pesticides (fungicides and insecticides) and 52 non-exposed were recruited. The farm workers were on average exposed to pesticides for ~3.7 h a day for 5 years. The frequency of BCL2-IGH t(14;18) translocation in workers occupationally exposed to pesticides was 10% (5 of 52) vs. 8% (4 of 52) in the control group. Overall, these data suggest that no significant association between occupational exposure to pesticides and an increased frequency of the chromosomal translocation BCL2-IGH t(14;18) in farmers was observed. However, further studies with a higher number of subjects exposed to pesticides are necessary to confirm this observation.
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Copy and paste a formatted citation
Spandidos Publications style
Rapisarda V, Ledda C, Matera S, Fago L, Arrabito G, Falzone L, Marconi A, Libra M and Loreto C: Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides. Mol Med Rep 15: 3379-3382, 2017.
APA
Rapisarda, V., Ledda, C., Matera, S., Fago, L., Arrabito, G., Falzone, L. ... Loreto, C. (2017). Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides. Molecular Medicine Reports, 15, 3379-3382. https://doi.org/10.3892/mmr.2017.6385
MLA
Rapisarda, V., Ledda, C., Matera, S., Fago, L., Arrabito, G., Falzone, L., Marconi, A., Libra, M., Loreto, C."Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides". Molecular Medicine Reports 15.5 (2017): 3379-3382.
Chicago
Rapisarda, V., Ledda, C., Matera, S., Fago, L., Arrabito, G., Falzone, L., Marconi, A., Libra, M., Loreto, C."Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides". Molecular Medicine Reports 15, no. 5 (2017): 3379-3382. https://doi.org/10.3892/mmr.2017.6385
Copy and paste a formatted citation
x
Spandidos Publications style
Rapisarda V, Ledda C, Matera S, Fago L, Arrabito G, Falzone L, Marconi A, Libra M and Loreto C: Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides. Mol Med Rep 15: 3379-3382, 2017.
APA
Rapisarda, V., Ledda, C., Matera, S., Fago, L., Arrabito, G., Falzone, L. ... Loreto, C. (2017). Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides. Molecular Medicine Reports, 15, 3379-3382. https://doi.org/10.3892/mmr.2017.6385
MLA
Rapisarda, V., Ledda, C., Matera, S., Fago, L., Arrabito, G., Falzone, L., Marconi, A., Libra, M., Loreto, C."Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides". Molecular Medicine Reports 15.5 (2017): 3379-3382.
Chicago
Rapisarda, V., Ledda, C., Matera, S., Fago, L., Arrabito, G., Falzone, L., Marconi, A., Libra, M., Loreto, C."Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides". Molecular Medicine Reports 15, no. 5 (2017): 3379-3382. https://doi.org/10.3892/mmr.2017.6385
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