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Article

Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study

  • Authors:
    • Margherita Ferrante
    • Maria Fiore
    • Gea Oliveri Conti
    • Valerio Fiore
    • Alfina Grasso
    • Chiara Copat
    • Salvatore Santo Signorelli
  • View Affiliations / Copyright

    Affiliations: Department of Medical, Surgical and Advanced Technologies ‘G.F. Ingrassia’, University of Catania, I-95123 Catania, Italy, Department of Clinical and Experimental Medicine, University of Catania, I-95123 Catania, Italy
  • Pages: 3438-3444
    |
    Published online on: March 24, 2017
       https://doi.org/10.3892/mmr.2017.6394
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Abstract

Our study compared copper (Cu), zinc (Zn) and manganese (Mn), crucial for human normal physio­logy maintenance, and lead (Pb) levels as environmental pollutant, in subjects suffering of deep vein thrombosis of lower limbs (DVTs) vs. healthy subjects. Furthermore, we evaluated oxidative stress parameters, the thiobarbituric acid reactive substances (TBARS) as the sum of malondialdehyde or 1,1,3,3-tetraethoxypropane (MDA) and 4-hydroxynonenal 4-HNE) and cytosolic superoxide dismutase (Cu/Zn-SOD) concentrations in both groups. We recruited 24 DVT cases and 46 healthy subjects as controls. Questionnaire with socio‑demographic, habits and lifestyle were collected. Hair concentrations of Zn, Mn, Cu and Pb were measured by ICP-MS, plasma concentrations of MDA and 4-HNE were measured by HPLC and SOD plasma concentrations were detected by ELISA test. A quantitative and qualitative variables comparison between cases and controls group was made by Mann-Whitney U test and Pearson's Chi-square test, respectively. We found low concentrations of Zn, Mn and Cu vs. high Pb concentrations in DVTs subjects. TBARS were found higher in the cases group, conversely, SOD concentrations were found lower in cases with respect to controls. Furthermore, we found the diet of pathological subjects significantly deficient in vegetables. These results are indicative of a lower enzymatic activity in patients, related to low transition metal levels in the DVTs and high levels of Pb, coupled with an unbalanced diet.
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1 

Goldhaber SZ: Pulmonary embolism thrombolysis: A clarion call for international collaboration. J Am Coll Cardiol. 19:246–247. 1992. View Article : Google Scholar : PubMed/NCBI

2 

Baccarelli A, Martinelli I, Zanobetti A, Grillo P, Hou LF, Bertazzi PA, Mannucci PM and Schwartz J: Exposure to particulate air pollution and risk of deep vein thrombosis. Arch Intern Med. 168:920–927. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Franchini M, Guida A, Tufano A and Coppola A: Air pollution, vascular disease and thrombosis: Linking clinical data and pathogenic mechanisms. J Thromb Haemost. 10:2438–2451. 2012. View Article : Google Scholar : PubMed/NCBI

4 

Franchini M and Mannucci PM: Particulate air pollution and cardiovascular risk: Short-term and long-term effects. Semin Thromb Hemost. 35:665–670. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Franchini M and Mannucci PM: Thrombogenicity and cardiovascular effects of ambient air pollution. Blood. 118:2405–2412. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Signorelli SS, Fiore V, Puccia G, Mastrosimone G and Anzaldi M: Thrombophilia in patients with lower limb deep veins thrombosis (LDVT). Results of a monocentric survey on 103 consecutive outpatients. Clin Appl Thromb Hemost. 20:589–593. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Fiore M, Ledda C, Rapisarda V, Sentina E, Mauceri C, DAgati P, Conti Oliveri G, Serra-Majem L and Ferrante M: Medical school fails to improve Mediterranean diet adherence among medical students. Eur J Public Health. 25:1019–1023. 2015. View Article : Google Scholar : PubMed/NCBI

8 

Agodi A, Barchitta M, Valenti G, Quattrocchi A, Marchese AE, Conti Oliveri G, Fallico R, Sciacca S and Ferrante M: Dietary folate intake and blood biomarkers reveal high-risk groups in a Mediterranean population of healthy women of childbearing potential. Ann Nutr Metab. 63:179–185. 2013. View Article : Google Scholar : PubMed/NCBI

9 

Sciacca S and Conti Oliveri G: Mutagens and carcinogens in drinking water. Med J Nutrition Metab. 2:157–162. 2009. View Article : Google Scholar

10 

World Health Organisation: Global status report on noncommunicable diseases 2010. World Health Organisation; Geneva: 2010

11 

Goldhaber SB: Trace element risk assessment: Essentiality vs. toxicity. Regul Toxicol Pharmacol. 38:232–242. 2003. View Article : Google Scholar : PubMed/NCBI

12 

Jomova K and Valko M: Advances in metal-induced oxidative stress and human disease. Toxicology. 283:65–87. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Santo SS, Sergio N, Luigi DP, Giuseppe M, Margherita F, Gea OC, Roberto F, Gabriella C, Giuseppe P and Massimiliano A: Effect of PLC on functional parameters and oxidative profile in type 2 diabetes-associated PAD. Diabetes Res Clin Pract. 72:231–237. 2006. View Article : Google Scholar : PubMed/NCBI

14 

Signorelli SS, Fatuzzo P, Rapisarda F, Neri S, Ferrante M, Conti Oliveri G, Fallico R, Di Pino L, Pennisi G, Celotta G, et al: A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis. Drugs Aging. 23:263–270. 2006. View Article : Google Scholar : PubMed/NCBI

15 

Reguig S, Bouanane S, Merzouk H, Soufi N and Merzouk S: Oxidative stress and thrombotic disorders: Study in patients with venous thromboembolism. Int J Health Sci Res. 6:185–194. 2016.

16 

Zhang X, Staimer N, Gillen DL, Tjoa T, Schauer JJ, Shafer MM, Hasheminassab S, Pakbin P, Vaziri ND, Sioutas C, et al: Associations of oxidative stress and inflammatory biomarkers with chemically-characterized air pollutant exposures in an elderly cohort. Environ Res. 150:306–319. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Busch CJ and Binder CJ: Malondialdehyde epitopes as mediators of sterile inflammation. Biochim Biophys Acta. Jun 26–2016.(Epub ahead of print).

18 

Papac-Milicevic N, Busch CJ and Binder CJ: Malondialdehyde epitopes as targets of immunity and the implications for atherosclerosis. Adv Immunol. 131:1–59. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Esterbauer H and Zollner H: Methods for determination of aldehydic lipid peroxidation products. Free Radic Biol Med. 7:197–203. 1989. View Article : Google Scholar : PubMed/NCBI

20 

Uriu-Adams JY and Keen CL: Copper, oxidative stress, and human health. Mol Aspects Med. 26:268–298. 2005. View Article : Google Scholar : PubMed/NCBI

21 

Chambers JC, Haskard DO and Kooner JS: Vascular endothelial function and oxidative stress mechanisms in patients with Behçets syndrome. J Am Coll Cardiol. 37:517–520. 2001. View Article : Google Scholar : PubMed/NCBI

22 

Brawn K and Fridovich I: Superoxide radical and superoxide dismutases: Threat and defense. Acta Physiol Scand (Suppl). 492:9–18. 1980.PubMed/NCBI

23 

Sinet PM and Garber P: Inactivation of the human CuZn superoxide dismutase during exposure to O2 and H2O2. Arch Biochem Biophys. 212:411–416. 1981. View Article : Google Scholar : PubMed/NCBI

24 

Harzallah O, Kerkeni A, Baati T and Mahjoub S: Oxidative stress: Correlation with Behçets disease duration, activity and severity. Eur J Intern Med. 19:541–547. 2008. View Article : Google Scholar : PubMed/NCBI

25 

Meng YY, Trachtenburg J, Ryan US and Abendschein DR: Potentiation of endogenous nitric oxide with superoxide dismutase inhibits platelet-mediated thrombosis in injured and stenotic arteries. J Am Coll Cardiol. 25:269–275. 1995. View Article : Google Scholar : PubMed/NCBI

26 

Ames BN, Shigenaga MK and Hagen TM: Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA. 90:7915–7922. 1993. View Article : Google Scholar : PubMed/NCBI

27 

Alissa E and Ferns G: Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases. J Nutr Metab. 2012:5694862012. View Article : Google Scholar : PubMed/NCBI

28 

Conte F, Copat C, Longo S, Conti GO, Grasso A, Arena G, Brundo MV and Ferrante M: First data on trace elements in Haliotis tuberculata (Linnaeus, 1758) from southern Italy: Safety issues. Food Chem Toxicol. 81:143–150. 2015. View Article : Google Scholar : PubMed/NCBI

29 

Conti GO, Copat C, Ledda C, Fiore M, Fallico R, Sciacca S and Ferrante M: Evaluation of heavy metals and polycyclic aromatic hydrocarbons (PAHs) in Mullus barbatus from Sicily Channel and risk-based consumption limits. Bull Environ Contam Toxicol. 88:946–950. 2012. View Article : Google Scholar : PubMed/NCBI

30 

Copat C, Bella F, Castaing M, Fallico R, Sciacca S and Ferrante M: Heavy metals concentrations in fish from Sicily (Mediterranean Sea) and evaluation of possible health risks to consumers. Bull Environ Contam Toxicol. 88:78–83. 2012. View Article : Google Scholar : PubMed/NCBI

31 

Copat C, Vinceti M, DAgati MG, Arena G, Mauceri V, Grasso A, Fallico R, Sciacca S and Ferrante M: Mercury and selenium intake by seafood from the Ionian Sea: A risk evaluation. Ecotoxicol Environ Saf. 100:87–92. 2014. View Article : Google Scholar : PubMed/NCBI

32 

Copat C, Arena G, Fiore M, Ledda C, Fallico R, Sciacca S and Ferrante M: Heavy metals concentrations in fish and shellfish from eastern Mediterranean Sea: Consumption advisories. Food Chem Toxicol. 53:33–37. 2013. View Article : Google Scholar : PubMed/NCBI

33 

Rabinowitz MB: Toxicokinetics of bone lead. Environ Health Perspect. 91:33–37. 1991. View Article : Google Scholar : PubMed/NCBI

34 

Hossain S, Bhowmick S, Islam S, Rozario L, Jahan S, Hassan M, Sarkar M, Choudhury BK, Ahmed S and Shahjalal H: Oral administration of Ganoderma lucidum to lead-exposed rats protects erythrocytes against hemolysis: Implicates to anti-anemia. Evid Based Complement Alternat Med. 2015:4637032015. View Article : Google Scholar : PubMed/NCBI

35 

Kaji T, Yamamoto C, Sakamoto M and Kozuka H: Inhibitory effect of lead on the release of tissue plasminogen activator from human vascular endothelial cells in culture. Toxicology. 73:219–227. 1992. View Article : Google Scholar : PubMed/NCBI

36 

Sun Y, Zhuang G, Zhang Z, Wang Y and Zhuang Y: Characteristics and sources of lead pollution after phasing out leaded gasoline in Beijing. Atmos Environ. 40:2973–2985. 2016. View Article : Google Scholar

37 

Sangani RG, Soukup JM and Ghio AJ: Metals in air pollution particles decrease whole-blood coagulation time. Inhal Toxicol. 22:621–626. 2010. View Article : Google Scholar : PubMed/NCBI

38 

Ghozikali Ghanbari M, Heibati B, Naddafi K, Kloog I, Conti Oliveri G, Polosa R and Ferrante M: Evaluation of chronic obstructive pulmonary disease (COPD) attributed to atmospheric O3, NO2, and SO2 using Air Q Model (2011–2012 year). Environ Res. 144:(Pt A). 99–105. 2016. View Article : Google Scholar : PubMed/NCBI

39 

Bind MA, Baccarelli A, Zanobetti A, Tarantini L, Suh H, Vokonas P and Schwartz J: Air pollution and markers of coagulation, inflammation, and endothelial function: Associations and epigene-environment interactions in an elderly cohort. Epidemiology. 23:332–340. 2012. View Article : Google Scholar : PubMed/NCBI

40 

Madrigano J, Baccarelli A, Mittleman MA, Wright RO, Sparrow D, Vokonas PS, Tarantini L and Schwartz J: Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men. Environ Health Perspect. 119:977–982. 2011. View Article : Google Scholar : PubMed/NCBI

41 

Mills NL, Donaldson K, Hadoke PW, Boon NA, MacNee W, Cassee FR, Sandström T, Blomberg A and Newby DE: Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med. 6:36–44. 2009. View Article : Google Scholar : PubMed/NCBI

42 

Piazza G and Goldhaber SZ: Venous thromboembolism and atherothrombosis: An integrated approach. Circulation. 121:2146–2150. 2010. View Article : Google Scholar : PubMed/NCBI

43 

Ageno W, Becattini C, Brighton T, Selby R and Kamphuisen PW: Cardiovascular risk factors and venous thromboembolism: A meta-analysis. Circulation. 117:93–102. 2008. View Article : Google Scholar : PubMed/NCBI

44 

Prandoni P: Venous and arterial thrombosis: Two aspects of the same disease? Clin Epidemiol. 1:1–6. 2009. View Article : Google Scholar : PubMed/NCBI

45 

Signorelli SS, Fiore V, Ruggieri M and Basile A: Acute deep vein thrombosis (DVT) of the lower limbs in a 32-year-old man with chronic hypoplasia of the inferior vena cava (HIVC) without risk factors. Intern Emerg Med. 11:273–275. 2016. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Ferrante M, Fiore M, Conti GO, Fiore V, Grasso A, Copat C and Signorelli SS: Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study. Mol Med Rep 15: 3438-3444, 2017.
APA
Ferrante, M., Fiore, M., Conti, G.O., Fiore, V., Grasso, A., Copat, C., & Signorelli, S.S. (2017). Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study. Molecular Medicine Reports, 15, 3438-3444. https://doi.org/10.3892/mmr.2017.6394
MLA
Ferrante, M., Fiore, M., Conti, G. O., Fiore, V., Grasso, A., Copat, C., Signorelli, S. S."Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study". Molecular Medicine Reports 15.5 (2017): 3438-3444.
Chicago
Ferrante, M., Fiore, M., Conti, G. O., Fiore, V., Grasso, A., Copat, C., Signorelli, S. S."Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study". Molecular Medicine Reports 15, no. 5 (2017): 3438-3444. https://doi.org/10.3892/mmr.2017.6394
Copy and paste a formatted citation
x
Spandidos Publications style
Ferrante M, Fiore M, Conti GO, Fiore V, Grasso A, Copat C and Signorelli SS: Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study. Mol Med Rep 15: 3438-3444, 2017.
APA
Ferrante, M., Fiore, M., Conti, G.O., Fiore, V., Grasso, A., Copat, C., & Signorelli, S.S. (2017). Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study. Molecular Medicine Reports, 15, 3438-3444. https://doi.org/10.3892/mmr.2017.6394
MLA
Ferrante, M., Fiore, M., Conti, G. O., Fiore, V., Grasso, A., Copat, C., Signorelli, S. S."Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study". Molecular Medicine Reports 15.5 (2017): 3438-3444.
Chicago
Ferrante, M., Fiore, M., Conti, G. O., Fiore, V., Grasso, A., Copat, C., Signorelli, S. S."Transition and heavy metals compared to oxidative parameter balance in patients with deep vein thrombosis: A case-control study". Molecular Medicine Reports 15, no. 5 (2017): 3438-3444. https://doi.org/10.3892/mmr.2017.6394
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