|
1
|
Yu SJ, Kim W, Kim D, Yoon JH, Lee K, Kim
JH, Cho EJ, Lee JH, Kim HY, Kim YJ and Kim CY: Visceral obesity
predicts significant fibrosis in patients with nonalcoholic fatty
liver disease. Medicine (Baltimore). 94:e21592015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Tolman KG, Fonseca V, Dalpiaz A and Tan
MH: Spectrum of liver disease in type 2 diabetes and management of
patients with diabetes and liver disease. Diabetes Care.
30:734–743. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Perry RJ, Samuel VT, Petersen KF and
Shulman GI: The role of hepatic lipids in hepatic insulin
resistance and type 2 diabetes. Nature. 510:84–91. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Fruci B, Giuliano S, Mazza A, Malaguarnera
R and Belfiore A: Nonalcoholic fatty liver: A possible new target
for type 2 diabetes prevention and treatment. Int J Mol Sci.
14:22933–22966. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Schinner S, Scherbaum WA, Bornstein SR and
Barthel A: Molecular mechanisms of insulin resistance. Diabet Med.
22:674–682. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Nordlie RC, Foster JD and Lange AJ:
Regulation of glucose production by the liver. Annu Rev Nutr.
19:379–406. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Taniguchi CM, Emanuelli B and Kahn CR:
Critical nodes in signaling pathways: Insights into insulin actio.
Nat Rev Mol Cell Biol. 7:85–96. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ishikawa M, Yoshida K, Okamura H, Ochiai
K, Takamura H, Fujiwara N and Ozaki K: Oral Porphyromonas
gingivalis translocates to the liver and regulates hepatic glycogen
synthesis through the Akt/GSK-3β signaling pathway. Biochim Biophys
Acta. 1832:2035–2043. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kim KM, Lee KS, Lee GY, Jin H, Durrance
ES, Park HS, Choi SH, Park KS, Kim YB, Jang HC and Lim S:
Anti-diabetic efficacy of KICG1338, a novel glycogen synthase
kinase-3β inhibitor and its molecular characterization in animal
models of type 2 diabetes and insulin resistance. Mol Cell
Endocrinol. 409:1–10. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Van Op den Bosch J, Adriaensen D, Van
Nassauw L and Timmermans JP: The role(s) of somatostatin,
structurally related peptides and somatostatin receptors in the
gastrointestinal tract: A review. Regul Pept. 156:1–8. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li W, Shi YH, Yang RL, Cui J, Xiao Y, Wang
B and Le GW: Effect of somatostatin analog on high-fat diet-induced
metabolic syndrome: Involvement of reactive oxygen species.
Peptides. 31:625–629. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Li M, Ye T, Wang XX, Li X, Qiang O, Yu T,
Tang CW and Liu R: Effect of octreotide on hepatic steatosis in
diet-induced obesity in rats. PLoS One. 11:e01520852016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Gupte AA, Liu JZ, Ren Y, Minze LJ, Wiles
JR, Collins AR, Lyon CJ, Pratico D, Finegold MJ, Wong ST, et al:
Rosiglitazone attenuates age- and diet-associated nonalcoholic
steatohepatitis in male low-density lipoprotein receptor knockout
mice. Hepatology. 52:2001–2011. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Sodhi K, Puri N, Favero G, Stevens S,
Meadows C, Abraham NG, Rezzani R, Ansinelli H, Lebovics E and
Shapiro JI: Fructose mediated non-alcoholic fatty liver is
Attenuated by HO-1-sirt1 module in murine hepatocytes and mice fed
a high fructose diet. PLoS One. 10:e01286482015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
López-Terrada D, Cheung SW, Finegold MJ
and Knowles BB: Hep G2 is a hepatoblastoma-derived cell line. Hum
Pathol. 40:1512–1515. 2009. View Article : Google Scholar
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ishikawa M, Yoshida K, Okamura H, Ochiai
K, Takamura H, Fujiwara N and Ozaki K: Oral Porphyromonas
gingivalis translocates to the liver and regulates hepatic glycogen
synthesis through the Akt/GSK-3β signaling pathway. Biochim Biophys
Acta. 1832:2035–2043. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Kumashiro N, Erion DM, Zhang D, Kahn M,
Beddow SA, Chu X, Still CD, Gerhard GS, Han X, Dziura J, et al:
Cellular mechanism of insulin resistance in nonalcoholic fatty
liver disease. Proc Natl Acad Sci USA. 108:16381–16385. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Gan L, Meng ZJ, Xiong RB, Guo JQ, Lu XC,
Zheng ZW, Deng YP, Luo BD, Zou F and Li H: Green tea polyphenol
epigallocatechin-3-gallate ameliorates insulin resistance in
non-alcoholic fatty liver disease mice. Acta Pharmacol Sin.
36:597–605. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Souza-Mello V: Peroxisome
proliferator-activated receptors as targets to treat non-alcoholic
fatty liver disease. World J Hepatol. 7:1012–1019. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hwang KA, Hwang YJ, Kim GR and Choe JS:
Extracts from Aralia elata (Miq) Seem alleviate hepatosteatosis via
improving hepatic insulin sensitivity. BMC Complement Altern Med.
15:3472015. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Musso G, Gambino R, Cassader M and Pagano
G: A meta-analysis of randomized trials for the treatment of
nonalcoholic fatty liver disease. Hepatology. 52:79–104. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Huang W, Liu R, Ou Y, Li X, Qiang O, Yu T
and Tang CW: Octreotide promotes weight loss via suppression of
intestinal MTP and apoB48 expression in diet-induced obesity rat.
Nutrition. 29:1259–1265. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Yang Y, Li W, Liu Y, Li Y, Gao L and Zhao
JJ: Alpha-lipoic acid attenuates insulin resistance and improves
glucose metabolism in high fat diet-fed mice. Acta Pharmacol Sin.
35:1285–1292. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Liu TY, Shi CX, Gao R, Sun HJ, Xiong XQ,
Ding L, Chen Q, Li YH, Wang JJ, Kang YM and Zhu GQ: Irisin inhibits
hepatic gluconeogenesis and increased glycogen synthesis via the
PI3K/Akt pathway in type 2 diabetic mice and hepatocytes. Clin Sci
(Lond). 129:839–850. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
MacAulay K and Woodgett JR: Targeting
glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2
diabetes. Expert Opin Ther Targets. 12:1265–1274. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lu M, Wan M, Leavens KF, Chu Q, Monks BR,
Fernandez S, Ahima RS, Ueki K, Kahn CR and Birnbaum MJ: Insulin
regulates liver metabolism in vivo in the absence of hepatic Akt
and Foxo1. Nat Med. 18:388–395. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ozcan L, de Cristina Souza J, Harari AA,
Backs J, Olson EN and Tabas I: Activation of
calcium/calmodulin-dependent protein kinase II in obesity mediates
suppression of hepatic insulin signaling. Cell Metab. 18:803–815.
2013. View Article : Google Scholar : PubMed/NCBI
|