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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2017 Volume 16 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Regulatory B cells in infectious disease (Review)

You‑Chao Dai, Jixin Zhong, Jun‑Fa Xu
Pages: 3-10
Published online on: 18 May 2017

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Review Open Access

Research and progress on ClC‑2 (Review)

Hongwei Wang, Minghui Xu, Qingjie Kong, Peng Sun, Fengyun Yan, Wenying Tian, Xin Wang
Pages: 11-22
Published online on: 18 May 2017

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Review

Proliferation‑inhibiting pathways in liver regeneration (Review)

Menggang Liu, Ping Chen
Pages: 23-35
Published online on: 19 May 2017

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Article Open Access

Galectin‑9 ameliorates fulminant liver injury

Tomoko Tadokoro, Asahiro Morishita, Teppei Sakamoto, Shintaro Fujihara, Koji Fujita, Shima Mimura, Kyoko Oura, Takako Nomura, Joji Tani, Hirohito Yoneyama, Hisakazu Iwama, Takashi Himoto, Toshiro Niki, Mitsuomi Hirashima, Tsutomu Masaki
Pages: 36-42
Published online on: 18 May 2017

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Article Open Access

DEC2 expression antagonizes cisplatin‑induced apoptosis in human esophageal squamous cell carcinoma

Hidenobu Sato, Yunyan Wu, Yukio Kato, Qiang Liu, Hideaki Hirai, Tadashi Yoshizawa, Satoko Morohashi, Jun Watanabe, Hiroshi Kijima
Pages: 43-48
Published online on: 11 May 2017

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Article Open Access

PPAR-α improves the recovery of lung function following acute respiratory distress syndrome by suppressing the level of TGF-β1

Yang Liu, Liping Xie, Mingquan Yang, Xiaofei Tan, Yonghong Zeng, Gang Zheng, Youying Chen, Ping Chen
Pages: 49-56
Published online on: 10 May 2017

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Article Open Access

Flow control effect of necrostatin-1 on cell death of the NRK-52E renal tubular epithelial cell line

Jialun Luo, Yiming Tao, Xinling Liang, Yuanhan Chen, Li Zhang, Fen Jiang, Shuangxin Liu, Zhiming Ye, Zhilian Li, Wei Shi
Pages: 57-62
Published online on: 09 May 2017

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Article Open Access

Differential effects of p38 and Erk1/2 on the chondrogenic and osteogenic differentiation of dental pulp stem cells

Pengfei Ba, Xiaoyu Duan, Guo Fu, Shuyan Lv, Pishan Yang, Qinfeng Sun
Pages: 63-68
Published online on: 10 May 2017

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Article Open Access

Long non‑coding RNA AB019562 promotes cell proliferation and metastasis in human hepatocellular carcinoma

Fan Wu, Jie Li, Xin Du, Weisan Zhang, Ping Lei, Qiang Zhang
Pages: 69-74
Published online on: 19 May 2017

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Article Open Access

Analysis of the CDR3 length repertoire and the diversity of T cell receptor α and β chains in swine CD4+ and CD8+ T lymphocytes

Chun‑Yan Wang, Yong‑Xiang Fang, Guo‑Hua Chen, Huai‑Jie Jia, Shuang Zeng, Xiao‑Bing He, Yuan Feng, Shou‑Jie Li, Qi‑Wang Jin, Wen‑Yu Cheng, Zhi‑Zhong Jing
Pages: 75-86
Published online on: 18 May 2017

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Article Open Access

Sodium tanshinone IIA sulfonate improves inflammation, aortic endothelial cell apoptosis, disseminated intravascular coagulation and multiple organ damage in a rat heat stroke model

Fang Chen, Huimin Li, Guoguo Zhu, Xiaojuan Chen, Zhongzhi Tang
Pages: 87-94
Published online on: 11 May 2017

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Article Open Access

Differentiation of nestin‑negative human hair follicle outer root sheath cells into neurons in vitro

Wei Wu, Xiao‑Li Wu, Yu‑Qing Ji, Zhen Gao
Pages: 95-100
Published online on: 16 May 2017

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Article Open Access

Combination of bortezomib and daunorubicin in the induction of apoptosis in T-cell acute lymphoblastic leukemia

Xin Du, Jia Tong, Hongying Lu, Cong He, Shenghong Du, Peimin Jia, Weili Zhao, Hanzhang Xu, Junmin Li, Zhixiang Shen, Yingli Wu, Jianhua Tong, Li Zhou
Pages: 101-108
Published online on: 09 May 2017

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Article Open Access

Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity

Xiao‑Xia Wang, Ting Ye, Mao Li, Xian Li, Ou Qiang, Cheng‑Wei Tang, Rui Liu
Pages: 109-118
Published online on: 16 May 2017

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Article Open Access

Effect of fasudil on cognitive function following status convulsion in rats

Rong He, Wei Han, Xiaojie Song, Xiaoju Tang, Li Cheng, Li Jiang
Pages: 119-126
Published online on: 19 May 2017

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Article Open Access

High‑throughput sequencing analyses of oral microbial diversity in healthy people and patients with dental caries and periodontal disease

Tingtao Chen, Yan Shi, Xiaolei Wang, Xin Wang, Fanjing Meng, Shaoguo Yang, Jian Yang, Hongbo Xin
Pages: 127-132
Published online on: 17 May 2017

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Article Open Access

Pre‑treatment with Chrysanthemum indicum Linné extract protects pyramidal neurons from transient cerebral ischemia via increasing antioxidants in the gerbil hippocampal CA1 region

In Hye Kim, Tae‑Kyeong Lee, Jeong Hwi Cho, Jae‑Chul Lee, Joon Ha Park, Ji Hyeon Ahn, Bich‑Na Shin, Bai Hui Chen, Hyun‑Jin Tae, Yang Hee Kim, Jong‑Dai Kim, Young‑Myeong Kim, Moo‑Ho Won, Il Jun Kang
Pages: 133-142
Published online on: 17 May 2017

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Article Open Access

miRNA‑1271 inhibits cell proliferation in neuroglioma by targeting fibronectin 1

Jian Gong, Zhao‑Xia Wang, Zhen‑Ying Liu
Pages: 143-150
Published online on: 19 May 2017

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Article Open Access

Overexpression of stromal interaction molecule 1 may promote epithelial‑mesenchymal transition and indicate poor prognosis in gastric cancer

Guobin Wu, Yong Li, Bibo Tan, Liqiao Fan, Qun Zhao, Yü Liu, Zhidong Zhang
Pages: 151-158
Published online on: 18 May 2017

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Article Open Access

C-terminus of OX2R significantly affects downstream signaling pathways

Chunmei Wang, Chao Xu, Minghui Liu, Yanyou Pan, Bo Bai, Jing Chen
Pages: 159-166
Published online on: 09 May 2017

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Article Open Access

MicroRNA‑141 inhibits the self‑renewal of glioblastoma stem cells via Jagged1

Xianfeng Gao, Xiaobo Zhu, Yang Sun, Jingwei Liu
Pages: 167-173
Published online on: 17 May 2017

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Article Open Access

Mitochondrial activity and oxidative stress functions are influenced by the activation of AhR-induced CYP1A1 overexpression in cardiomyocytes

Bing Zhou, Xi Wang, Feng Li, Yingting Wang, Lei Yang, Xiaolong Zhen, Wuhong Tan
Pages: 174-180
Published online on: 12 May 2017

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Article Open Access

Microarray analysis of differentially expressed genes in L929 mouse fibroblast cells exposed to leptin and hypoxia

Ping Ouyang, Sen Wang, He Zhang, Zhigang Huang, Pei Wei, Ye Zhang, Zhuguo Wu, Tao Li
Pages: 181-191
Published online on: 17 May 2017

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Article Open Access

Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats Corrigendum in /10.3892/mmr.2018.8625

Xinwei Liu, Jingdong Zhang, Wenfeng Han, Yu Wang, Yunen Liu, Yubiao Zhang, Dapeng Zhou, Liangbi Xiang
Pages: 192-200
Published online on: 09 May 2017

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Case Report Open Access

Hypospadias in a male infant with an unusual mosaic 45,X/46,X,psu idic(Y)(p11.32)/46,XY and haploinsufficiency of SHOX: A case report

Yan‑Mei Si, Yuan Dong, Wei Wang, Ke‑Yan Qi, Xin Wang
Pages: 201-207
Published online on: 10 May 2017

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Article Open Access

Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro

Xiaorong Mao, Senrong Du, Zhongxia Yang, Liting Zhang, Xuebin Peng, Ni Jiang, Haiyu Zhou
Pages: 208-214
Published online on: 10 May 2017

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Article Open Access

Proteomic analysis of differentially expressed proteins in kidneys of brain dead rabbits

Ling Li, Ning Li, Chongxiang He, Wei Huang, Xiaoli Fan, Zibiao Zhong, Yanfeng Wang, Qifa Ye
Pages: 215-223
Published online on: 19 May 2017

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Article

High expression of PFTK1 in cancer cells predicts poor prognosis in colorectal cancer

Youjun Mao, Yuqing Jia, Huijun Zhu, Wei Wang, Qin Jin, Fang Huang, Shu Zhang, Xiaoqiang Li
Pages: 224-230
Published online on: 10 May 2017

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Article Open Access

Expression of c-FLIP in a rat model of sepsis and its effects on endothelial apoptosis

Lei Shen, Zhengda Sun, Feng Zhao, Wei Wang, Wenhong Zhang, Hechen Zhu
Pages: 231-237
Published online on: 10 May 2017

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Article Open Access

Identification of miR‑124a as a novel diagnostic and prognostic biomarker in non‑small cell lung cancer for chemotherapy

Pei Luo, Qing Yang, Le‑Le Cong, Xiao‑Feng Wang, Yu‑Sheng Li, Xiao‑Ming Zhong, Ru‑Ting Xie, Cheng‑You Jia, Hui‑Qiong Yang, Wen‑Ping Li, Xian‑Ling Cong, Qing Xia, Da Fu, Qing‑Hua Zeng, Yu‑Shui Ma
Pages: 238-246
Published online on: 17 May 2017

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Article Open Access

miR-590 regulates WT1 during proliferation of G401 cells

Liyi Hong, Xu Zhao, Xuejun Shao, Hong Zhu
Pages: 247-253
Published online on: 10 May 2017

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Article Open Access

High expression levels of the D686N Parkinson's disease mutation in VPS35 induces α-synuclein-dependent toxicity in yeast

Yi Huang, Xiang Chen, Xiaofei He, Caifeng Guo, Xicui Sun, Fengyin Liang, Simei Long, Xilin Lu, Luyang Feng, Wenyuan Guo, Yixuan Zeng, Zhong Pei
Pages: 254-262
Published online on: 09 May 2017

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Article Open Access

Embryotoxicity estimation of commonly used compounds with embryonic stem cell test

Hui Liu, Caiping Ren, Weidong Liu, Xingjun Jiang, Lei Wang, Bin Zhu, Wei Jia, Jianxing Lin, Jun Tan, Xiuying Liu
Pages: 263-271
Published online on: 09 May 2017

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Article Open Access

A proteomic analysis identifies candidate early biomarkers to predict ovarian hyperstimulation syndrome in polycystic ovarian syndrome patients

Lan Wu, Yazhou Sun, Jun Wan, Ting Luan, Qing Cheng, Yong Tan
Pages: 272-280
Published online on: 18 May 2017

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Article Open Access

Bioinformatic analysis of the effects and mechanisms of decitabine and cytarabine on acute myeloid leukemia

Shiyong Zhou, Pengfei Liu, Huilai Zhang
Pages: 281-287
Published online on: 12 May 2017

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Article Open Access

Sanguinarine protects against ovariectomy‑induced osteoporosis in mice

Yan Ma, Junjie Chu, Jianjun Ma, Lei Ning, Ke Zhou, Xiangqian Fang
Pages: 288-294
Published online on: 11 May 2017

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Article

Neokestose suppresses the growth of human melanoma A2058 cells via inhibition of the nuclear factor‑κB signaling pathway

Jiann‑Shing Wu, Jan‑Yi Chang, C. Will Chen, Ming‑Tse Lin, Dey‑Chyi Sheu, Shun‑Mei Lee
Pages: 295-300
Published online on: 17 May 2017

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Article

Molecular analysis of the mouse brain exposed to chronic mild stress: The influence of hepatocyte nuclear factor 4α on physiological homeostasis

Kaoru Ikubo, Kyosuke Yamanishi, Nobutaka Doe, Takuya Hashimoto, Miho Sumida, Yuko Watanabe, Yosif El‑Darawish, Wen Li, Haruki Okamura, Hiromichi Yamanishi, Hisato Matsunaga
Pages: 301-309
Published online on: 11 May 2017

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Article

Respiratory syncytial virus infection accelerates lung fibrosis through the unfolded protein response in a bleomycin-induced pulmonary fibrosis animal model

Lina Wang, Wei Cheng, Zhimin Zhang
Pages: 310-316
Published online on: 10 May 2017

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Article

Low‑level mechanical vibration enhances osteoblastogenesis via a canonical Wnt signaling‑associated mechanism

Heqi Gao, Mingming Zhai, Pan Wang, Xuhui Zhang, Jing Cai, Xiaofei Chen, Guanghao Shen, Erping Luo, Da Jing
Pages: 317-324
Published online on: 19 May 2017

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Article

Role of X‑linked inhibitor of apoptosis‑associated factor‑1 in vasculogenic mimicry in ovarian cancer

Yunxia Wang, Peishu Liu, Xietong Wang, Hongluan Mao
Pages: 325-330
Published online on: 17 May 2017

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Article

RPN11 deubiquitinase promotes proliferation and migration of breast cancer cells

Guoqing Luo, Ningdong Hu, Xu Xia, Jingjing Zhou, Changsheng Ye
Pages: 331-338
Published online on: 16 May 2017

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Article

Spilanthes acmella inhibits inflammatory responses via inhibition of NF-κB and MAPK signaling pathways in RAW 264.7 macrophages

Young‑Chang Cho, Tran The Bach, Ba Reum Kim, Huong Lan Vuong, Sayeon Cho
Pages: 339-346
Published online on: 09 May 2017

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Article

Elevated SLC26A4 gene promoter methylation is associated with the risk of presbycusis in men

Jin Xu, Jiachen Zheng, Wanjing Shen, Lili Ma, Ming Zhao, Xubo Wang, Jiyuan Tang, Jihong Yan, Zhenhua Wu, Zuquan Zou, Shizhong Bu, Yang Xi
Pages: 347-352
Published online on: 10 May 2017

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Article

Mus musculus-microRNA-449a ameliorates neuropathic pain by decreasing the level of KCNMA1 and TRPA1, and increasing the level of TPTE

Shan Lu, Sichao Ma, Yunyun Wang, Tao Huang, Zhihua Zhu, Guoqing Zhao
Pages: 353-360
Published online on: 10 May 2017

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Article

Effects of unfractionated heparin and rivaroxaban on the expression of heparanase and fibroblast growth factor 2 in human osteoblasts

Jingjun Xia, Wei Sheng, Liubao Pei, Ning Li, Zhipeng Zhang, Jialiang Wang, Jianing Zu, Nanxiang Wang, Duanyang Wang
Pages: 361-366
Published online on: 10 May 2017

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Article

Reduced expression of follicle stimulating hormone receptor mRNA and protein in pregnancies complicated by pre‑eclampsia

Mo Li, Yifan Jia, Yan Ling, Yilu Chen, Lu Zhang, Dan Luo, Lidan Lai, Meijun Guo, Dalei Zhang, Min Ren, Hong Xu, Haibin Kuang
Pages: 367-372
Published online on: 18 May 2017

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Article

Demethylzeylasteral ameliorates inflammation in a rat model of unilateral ureteral obstruction through inhibiting activation of the NF‑κB pathway

Qiang Wang, Yanmei Xiao, Tongwei Liu, Haibo Yuan, Chunwu Li
Pages: 373-379
Published online on: 16 May 2017

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Article

Luteolin-induced apoptosis through activation of endoplasmic reticulum stress sensors in pheochromocytoma cells

Kisang Kwon, Young‑Sook Kwon, Seung‑Whan Kim, Kweon Yu, Kyung‑Ho Lee, O‑Yu Kwon
Pages: 380-386
Published online on: 12 May 2017

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Article

Neuropeptide Y suppresses epileptiform discharges by regulating AMPA receptor GluR2 subunit in rat hippocampal neurons

Wei Bu, Wen‑Qing Zhao, Wen‑Ling Li, Chang‑Zheng Dong, Zhe Zhang, Qi‑Jun Li
Pages: 387-395
Published online on: 10 May 2017

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Article

Synergistic protective effect of FTY720 and vitamin E against simulated cerebral ischemia in vitro

Xin Pang, Xuening Hou
Pages: 396-402
Published online on: 11 May 2017

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Article

Contribution of methylglyoxal to delayed healing of bone injury in diabetes

Takao Aikawa, Hidenori Matsubara, Shuhei Ugaji, Junichi Shirakawa, Ryoji Nagai, Seiichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Hiroyuki Tsuchiya
Pages: 403-409
Published online on: 16 May 2017

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Article

Whole‑exome sequencing identifies a novel mutation (R367G) in SCN5A to be associated with familial cardiac conduction disease

Rong Yu, Xue‑Feng Fan, Chan Chen, Zheng‑Hua Liu
Pages: 410-414
Published online on: 17 May 2017

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Article

Correlation of four potential biomarkers of liver fibrosis with liver function and grade of hepatic fibrosis in a neonatal cholestatic rat model

Ning Tang, Yaping Zhang, Zeyu Liu, Xuemei Ai, Qinghong Liang
Pages: 415-421
Published online on: 16 May 2017

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Article

PER2 is downregulated by the LPS-induced inflammatory response in synoviocytes in rheumatoid arthritis and is implicated in disease susceptibility

Hwayoung Lee, Seong‑Su Nah, Sung‑Hae Chang, Hyung‑Ki Kim, Jun‑Tack Kwon, Sanghyun Lee, Ik‑Hyun Cho, Sang Won Lee, Young Ock Kim, Seung‑Jae Hong, Hak‑Jae Kim
Pages: 422-428
Published online on: 11 May 2017

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Article

How much medium do you use for cell culture? Medium volume influences mineralization and osteoclastogenesis in vitro

Yoshitaka Yoshimura, Takashi Kikuiri, Tomokazu Hasegawa, Mino Matsuno, Hajime Minamikawa, Yoshiaki Deyama, Kuniaki Suzuki
Pages: 429-434
Published online on: 19 May 2017

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Article

Effects of exercise on mature or precursor brain‑derived neurotrophic factor pathways in ovariectomized rats

Joon‑Ki Park, Young‑Pyo Hong, Sam‑Jun Lee
Pages: 435-440
Published online on: 19 May 2017

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Article

hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer

Wojciech Barczak, Wiktoria M. Suchorska, Agnieszka Sobecka, Karolina Bednarowicz, Piotr Machczynski, Pawel Golusinski, Blazej Rubis, Michal M. Masternak, Wojciech Golusinski
Pages: 441-446
Published online on: 17 May 2017

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Article

Increased production of human fibroblast growth factor 17 in Escherichia coli and proliferative activity in NIH3T3 cells

Meiyu Wu, Na Song, Jiliang Cheng, Yang Zhao, Nazi Chen, Jisheng Ma, Xiaokun Li, Chao Jiang, Haijun Wang
Pages: 447-452
Published online on: 11 May 2017

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Article

Dexamethasone reduces side population fraction through downregulation of ABCG2 transporter in MCF-7 breast cancer cells

Jong Bin Kim, Sung Eun Hwang, Sang‑Pil Yoon
Pages: 453-458
Published online on: 10 May 2017

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Article

Inhibition of prostate cancer RM1 cell growth in vitro by hydroxyapatite nanoparticle‑delivered short hairpin RNAs against Stat3

Zuowen Liang, Hongliang Wang, Baofeng Guo, Fubiao Li, Jinsha Liu, Zhewen Liu, Libo Xu, Wenjing Yun, Xuejian Zhao, Ling Zhang
Pages: 459-465
Published online on: 16 May 2017

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Article

MicroRNA‑296 targets AKT2 in pancreatic cancer and functions as a potential tumor suppressor

Hailing Li, Jilin Li, Baolin Shi, Feng Chen
Pages: 466-472
Published online on: 18 May 2017

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Article

Identification of a missense HOXD13 mutation in a Chinese family with syndactyly type I-c using exome sequencing

Hao Deng, Ting Tan, Quanyong He, Qiongfen Lin, Zhijian Yang, Anding Zhu, Liping Guan, Jingjing Xiao, Zhi Song, Yi Guo
Pages: 473-477
Published online on: 11 May 2017

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Article

Tamoxifen promotes apoptosis and inhibits invasion in estrogen‑positive breast cancer MCF‑7 cells

Wei Li, Xingpeng Shi, Yan Xu, Jianmei Wan, Shaohua Wei, Ran Zhu
Pages: 478-484
Published online on: 18 May 2017

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Effects of maternal acrolein exposure during pregnancy on testicular testosterone production in fetal rats

Yuzhuo Yang, Zhe Zhang, Hongliang Zhang, Kai Hong, Wenhao Tang, Lianming Zhao, Haocheng Lin, Defeng Liu, Jiaming Mao, Han Wu, Hui Jiang
Pages: 491-498
Published online on: 25 May 2017

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Clinical significance and prognostic value of SOX7 expression in liver and pancreatic carcinoma

Jian Wang, Shengmin Zhang, Jiamian Wu, Zhuocai Lu, Jianrong Yang, Hongsheng Wu, Hao Chen, Bo Lin, Tiansheng Cao
Pages: 499-506
Published online on: 31 May 2017

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A comparative study of the influence of two types of PHEMA stents on the differentiation of ASCs to myocardial cells

Shen Lao, Jing Xu, Yunqi Liu, Songwang Cai, Lin Lin, Junhang Zhang, Dongmei Cai, Shengli Yin
Pages: 507-514
Published online on: 01 June 2017

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Remote ischemic postconditioning confers neuroprotective effects via inhibition of the BID-mediated mitochondrial apoptotic pathway

Xiaoying Gao, Yun Liu, Yuying Xie, Ying Wang, Sihua Qi
Pages: 515-522
Published online on: 30 May 2017

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Investigating critical genes and gene interaction networks that mediate cyclophosphamide sensitivity in chronic myelogenous leukemia

Xiao He, Yuying Deng, Wei Yue
Pages: 523-532
Published online on: 26 May 2017

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Schisandrin B attenuates the inflammatory response, oxidative stress and apoptosis induced by traumatic spinal cord injury via inhibition of p53 signaling in adult rats

D. Q. Xin, Z. M. Hu, H. J. Huo, X. J. Yang, D. Han, W. H. Xing, Y. Zhao, Q. H. Qiu
Pages: 533-538
Published online on: 25 May 2017

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Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells

Yaoqun Wu, Pei Zhang, Hongyun Yang, Yong Ge, Yong Xin
Pages: 539-546
Published online on: 31 May 2017

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Effects of cryopreservation on excretory function, cellular adhesion molecules and vessel lumen formation in human umbilical vein endothelial cells

Guoping Cai, Binbin Lai, Huaxing Hong, Peng Lin, Weifu Chen, Zhong Zhu, Haixiao Chen
Pages: 547-552
Published online on: 31 May 2017

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Identification of critical genes in nucleus pulposus cells isolated from degenerated intervertebral discs using bioinformatics analysis

Zhuangchen Zhu, Guang Chen, Wei Jiao, Defeng Wang, Yan Cao, Qingfu Zhang, Junqin Wang
Pages: 553-564
Published online on: 31 May 2017

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Enhanced effect of nuclear localization signal peptide during ultrasound‑targeted microbubble destruction‑mediated gene transfection

Sheng Cao, Qing Zhou, Jin‑Ling Chen, Nan Jiang, Yi‑Jia Wang, Qing Deng, Bo Hu, Rui‑Qiang Guo
Pages: 565-572
Published online on: 31 May 2017

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Investigation of the major cytochrome P450 1A2 genetic variant in a healthy Tibetan population in China

Yongchao Ren, Fang Liu, Xugang Shi, Tingting Geng, Dongya Yuan, Li Wang, Longli Kang, Tianbo Jin, Chao Chen
Pages: 573-580
Published online on: 29 May 2017

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MicroRNA expression analysis during FK506-induced osteogenic differentiation in rat bone marrow stromal cells

Jing Zhang, Xiaoping Yu, Youcheng Yu, Yiming Gong
Pages: 581-590
Published online on: 31 May 2017

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The expression of DNA methyltransferases3A is specifically downregulated in chorionic villi of early embryo growth arrest cases

Huating Gu, Jing Gao, Weiwei Guo, Yu Zhou, Qingnuan Kong
Pages: 591-596
Published online on: 30 May 2017

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Nrf2 mediates the protective effects of homocysteine by increasing the levels of GSH content in HepG2 cells

Bing Zhang, Jing‑Lin Dong, Ying‑Li Chen, Yang Liu, Shi‑Shun Huang, Xiu‑Li Zhong, Yu‑Hong Cheng, Zhi‑Gang Wang
Pages: 597-602
Published online on: 25 May 2017

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Microglia activation triggers oligodendrocyte precursor cells apoptosis via HSP60

Yunhong Li, Rui Zhang, Xiaolin Hou, Yumei Zhang, Feijia Ding, Fan Li, Yao Yao, Yin Wang
Pages: 603-608
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Bioinformatics analyses of the differences between lung adenocarcinoma and squamous cell carcinoma using The Cancer Genome Atlas expression data

Fenghao Sun, Xiaodong Yang, Yulin Jin, Li Chen, Lin Wang, Mengkun Shi, Cheng Zhan, Yu Shi, Qun Wang
Pages: 609-616
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σ-1 receptor stimulation protects against pressure-induced damage through InsR-MAPK signaling in human trabecular meshwork cells

Bo Meng, Hongyi Li, Xian Sun, Wei Qu, Binbin Yang, Fang Cheng, Liping Shi, Huiping Yuan
Pages: 617-624
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A nanobody targeting carcinoembryonic antigen as a promising molecular probe for non-small cell lung cancer

Hao Wang, Ai‑Min Meng, Sheng‑Hua Li, Xiao‑Liang Zhou
Pages: 625-630
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Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway

Liping Liu, Hongli Yu, Hao Wu, Xiaolin Yang, Yaozong Pan, Yeqing Chen, Kuilong Wang, Wei Wang, Wenying Zhang, Yangping Jin, Chengchao Zhang, Ai Jiang, Chunyan Xia
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Prostaglandin E2 promotes human CD34+ cells homing through EP2 and EP4 in vitro

Yaqun Wang, Shuping Lai, Jing Tang, Chun Feng, Fangjie Liu, Chang Su, Waiyi Zou, Huizhen Chen, Duorong Xu
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Modified citrus pectin inhibits galectin-3 function to reduce atherosclerotic lesions in apoE-deficient mice

Yonggang Lu, Mingming Zhang, Pei Zhao, Min Jia, Bing Liu, Qian Jia, Jun Guo, Lin Dou, Jian Li
Pages: 647-653
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Bone marrow stromal cells promote neuromotor functional recovery, via upregulation of neurotrophic factors and synapse proteins following traumatic brain injury in rats

Yan Feng, Yaru Ju, Jianzhong Cui, Liqun Wang
Pages: 654-660
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Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus

Joon Ha Park, Jin‑A Park, Ji Hyeon Ahn, Yang Hee Kim, Il Jun Kang, Moo‑Ho Won, Choong‑Hyun Lee
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Tensile strength suppresses the osteogenesis of periodontal ligament cells in inflammatory microenvironments

Chaofan Sun, Fen Liu, Shendan Cen, Lijiao Chen, Yi Wang, Hao Sun, Hui Deng, Rongdang Hu
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Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice Corrigendum in /10.3892/mmr.2017.7698

Jianshu Gao, Xiaoqiang Liu, Bingjian Wang, Haiyan Xu, Qiang Xia, Tianfei Lu, Fang Wang
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Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD‑induced obese mice

Min Li, Antara Sharma, Chunyan Yin, Xinrui Tan, Yanfeng Xiao
Pages: 680-686
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Differential expression of miRNAs in Osborne's ligament of cubital tunnel syndrome

Xian‑Hu Zhou, Yi‑Ming Ren, Zhi‑Jian Wei, Wei Lin, Bao‑You Fan, Shen Liu, Yan Hao, Gui‑Dong Shi, Shi‑Qing Feng
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Revealing radiotherapy- and chemoradiation-induced pathway dynamics in glioblastoma by analyzing multiple differential networks

Jia Zhou, Chao Chen, Hua‑Feng Li, Yu‑Jie Hu, Hong‑Ling Xie
Pages: 696-702
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Effects of the Tangningtongluo formula as an alternative strategy for diabetics via upregulation of insulin receptor substrate-1 Corrigendum in /10.3892/mmr.2019.10649

Long Cheng, Junmei Song, Geng Li, Yue Liu, Yuming Wang, Xiangbao Meng, Guibo Sun, Xiaobo Sun
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A novel missense mutation in the ALPL gene causes dysfunction of the protein

Bin Chen, Lili Li, Weitong Ren, Long Yi, Yaping Wang, Fuhua Yan
Pages: 710-718
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Multiple Nav1.5 isoforms are functionally expressed in the brain and present distinct expression patterns compared with cardiac Nav1.5

Jun Wang, Shao‑Wu Ou, Yun‑Fei Bai, Yun‑Jie Wang, Zhi‑Qing David Xu, Guo‑Ming Luan
Pages: 719-729
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The inhibition of NOTCH2 reduces UVB-induced damage in retinal pigment epithelium cells

Lanying Liu, Xin Zhou, Xielan Kuang, Chongde Long, Weiwei Liu, Yan Tang, Huijun Liu, Jia He, Zixin Huang, Yuting Fan, Qingjiong Zhang, Huangxuan Shen
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Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway Corrigendum in /10.3892/mmr.2022.12658

Yongheng Bai, Cunzao Wu, Weilong Hong, Xing Zhang, Leping Liu, Bicheng Chen
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Epigenetically silenced PTPRO functions as a prognostic marker and tumor suppressor in human lung squamous cell carcinoma

Fei Ming, Qianqiang Sun
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MicroRNA-146a promotes gastric cancer cell apoptosis by targeting transforming growth factor β-activated kinase 1

Yiming Chen, Bin Zhou, Lubai Xu, Hengwei Fan, Junqin Xie, Dan Wang
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HSVtk/GCV system on hepatoma carcinoma cells: Construction of the plasmid pcDNA3.1‑pAFP-TK and targeted killing effect

Yong‑Fang Li, Yang‑Yang Yuan, Ying‑Min Zhang, Na Zhao, Qi Zhang, Fan‑Xiu Meng, Ran‑Peng Gao, Bao‑Feng Yu, Yue‑Hong Zhang, Rui Guo, Hai‑Long Wang, Jun Xie, Jun Xu, Qin Qin, Xiu‑Shan Dong
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A novel approach to select differential pathways associated with hypertrophic cardiomyopathy based on gene co‑expression analysis

Xiao‑Min Chen, Ming‑Jun Feng, Cai‑Jie Shen, Bin He, Xian‑Feng Du, Yi‑Bo Yu, Jing Liu, Hui‑Min Chu
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Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17‑mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro

Feng‑Ming Ding, Ruo‑Min Liao, Yu‑Qing Chen, Guo‑Gang Xie, Peng‑Yu Zhang, Ping Shao, Min Zhang
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Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1

Haibin Gong, Xiuli Wang, Lei Wang, Ying Liu, Jie Wang, Qian Lv, Hui Pang, Qinglin Zhang, Zhenquan Wang
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Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase

Yi Zhang, Xu Sun, Nan Nan, Ke‑Xin Cao, Cong Ma, Guo‑Wang Yang, Ming‑Wei Yu, Lin Yang, Jin‑Ping Li, Xiao‑Min Wang, Gan‑Lin Zhang
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Differences in molecular regulation between osteochondroma and bizarre parosteal osteochondromatous proliferation

Xinrong Zhou, Lihui Deng, Xinsheng Han, Yi Chen, Jiao Wang, Shengnan Du
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Prognostic value of PAX9 in patients with esophageal squamous cell carcinoma and its prediction value to radiation sensitivity

Bingxu Tan, Jianbo Wang, Qingxu Song, Nana Wang, Yibin Jia, Cong Wang, Bin Yao, Zhulong Liu, Xiaomei Zhang, Yufeng Cheng
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Atheroprotective effects of statins in patients with unstable angina by regulating the blood-borne microRNA network

Sufang Li, Chengfu Cao, Hong Chen, Junxian Song, Chongyou Lee, Jing Zhang, Feng Zhang, Qiang Geng, Zheng Li, Jingjin Li
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Article

Altered expression of epithelial mesenchymal transition and pluripotent associated markers by sex steroid hormones in human embryonic stem cells

So‑Ye Jeon, Kyung‑A Hwang, Cho‑Won Kim, Eui‑Bae Jeung, Kyung‑Chul Choi
Pages: 828-836
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Article

MicroRNA-526a targets p21-activated kinase 7 to inhibit tumorigenesis in hepatocellular carcinoma Retraction in /10.3892/mmr.2023.13007

Lei Zhan, Yaozhen Pan, Ling Chen, Zili Chen, Hong Zhang, Chengyi Sun
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Article

Underlying mechanism of Sirt1 on apoptosis and extracellular matrix degradation of osteoarthritis chondrocytes

Dong‑Sheng He, Xiao‑Jian Hu, Yi‑Qi Yan, Hui Liu
Pages: 845-850
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Immunogenicity and immunoreactivity of Tp0821 recombinant protein from Treponema pallidum

Ning Wu, Ni Li, Liping Hu, Jun He, Junhong Li, Feijun Zhao, Yimou Wu
Pages: 851-856
Published online on: 01 June 2017

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Article

Araliasaponin II isolated from leaves of Acanthopanax henryi (Oliv.) Harms inhibits inflammation by modulating the expression of inflammatory markers in murine macrophages

Yun‑Soo Seo, Seok‑Jeon Lee, Zhi Li, Ok‑Hwa Kang, Ryong Kong, Sang‑A Kim, Tian Zhou, Yung‑Sun Song, Xiangqian Liu, Dong‑Yeul Kwon
Pages: 857-864
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Article

Effects of interleukin-17 on human retinal vascular endothelial cell capillary tube formation in vitro

Gaoqin Liu, Hongya Wu, Lei Chen, Jing Xu, Mengjiao Wang, Dan Li, Peirong Lu
Pages: 865-872
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Article

Genistein and menaquinone-4 treatment-induced alterations in the expression of mRNAs and their products are beneficial to osteoblastic MC3T3-E1 cell functions

Midori Katsuyama, Masashi Demura, Hironobu Katsuyama, Hideji Tanii, Kiyofumi Saijoh
Pages: 873-880
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Article

Altered gene expression of hepatic cytochrome P450 in a rat model of intermittent hypoxia with emphysema

Hongzhi Yu, Hongxia Shao, Qi Wu, Xin Sun, Li Li, Kuan Li, Xue Li, Yu Li, Qiuyang Zhang, Junping Wu, Huaiyong Chen
Pages: 881-886
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Article

Increased SLC7A8 expression mediates L-DOPA uptake by renal tubular epithelial cells

Yihao Wu, Qiqi Yin, Su Lin, Xiaoyan Huang, Quan Xia, Zhe Chen, Xingwei Zhang, Deye Yang
Pages: 887-893
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Article

An FGF8b-mimicking peptide with potent antiangiogenic activity

Xiaomian Lin, Li Song, Dan He, Xiangfeng Zeng, Jianzhang Wu, Wu Luo, Qi Yang, Jizhong Wang, Tianxiang Wang, Jialong Cai, Yanling Lin, Fubin Lai, Wentao Peng, Xiaoping Wu
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CpG methylation patterns are associated with gene expression variation in osteosarcoma

Qiang Wang
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Article

VPA and MEL induce apoptosis by inhibiting the Nrf2-ARE signaling pathway in TMZ-resistant U251 cells

Hao Pan, Handong Wang, Yue Jia, Qiang Wang, Liwen Li, Qi Wu, Longbang Chen
Pages: 908-914
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Article

Noninvasive detection of acute renal allograft rejection by measurement of soluble Tim-3 in urine

Dajin Chen, Wenhan Peng, Hong Jiang, Hao Yang, Jianyong Wu, Huiping Wang, Jianghua Chen
Pages: 915-921
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Article

Rutaecarpine alleviates renal ischemia reperfusion injury in rats by suppressing the JNK/p38 MAPK signaling pathway and interfering with the oxidative stress response

Chunhua Wang, Zongyao Hao, Jun Zhou, Li Zhang, Yexiang Sun, Chaozhao Liang
Pages: 922-928
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Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1

Yan‑Hong Sun, Lan He, Ming‑Yu Yan, Rui‑Qian Zhao, Bin Li, Feng Wang, Ying Yang, Hua‑Peng Yu
Pages: 929-936
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Article

Lymphotoxin β receptor activation promotes mRNA expression of RelA and pro-inflammatory cytokines TNFα and IL-1β in bladder cancer cells

Mo Shen, Lianlian Zhou, Ping Zhou, Wu Zhou, Xiangyang Lin
Pages: 937-942
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Sufentanil attenuates oxaliplatin cytotoxicity via inhibiting connexin 43‑composed gap junction function

Qi Zhang, Min Su
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Inhibitory capacity of Rhus coriaria L. extract and its major component methyl gallate on Streptococcus mutans biofilm formation by optical profilometry: Potential applications for oral health

Tomas Kacergius, Saleh Abu‑Lafi, Agne Kirkliauskiene, Vika Gabe, Azmi Adawi, Mahmoud Rayan, Mutaz Qutob, Rimantas Stukas, Algirdas Utkus, Mouhammad Zeidan, Anwar Rayan
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The restraining effect of baicalein and U0126 on human cervical cancer cell line HeLa

Haiqiong Ye, Yujiao Zhang, Yongzhou Wang, Jiyi Xia, Xiguang Mao, Xiaolan Yu
Pages: 957-963
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Hypomethylation of the Toll-like receptor-2 gene increases the risk of essential hypertension

Shuqi Mao, Tianlun Gu, Fade Zhong, Rui Fan, Fubao Zhu, Peipei Ren, Fengying Yin, Lina Zhang
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Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway

Peifeng Qiao, Fengli Zhao, Mengjie Liu, Dan Gao, Hua Zhang, Yong Yan
Pages: 971-977
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Apoptosis is induced by docosahexaenoic acid in breast cancer cells via death receptor and mitochondria-mediated pathways

Meilan Xue, Yinlin Ge, Chundong Yu, Zheng Zheng, Xinjia He, Jinglan Zhao
Pages: 978-982
Published online on: 01 June 2017

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Ayman A. Althubity
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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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