|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Yang P, Allen MS, Aubry MC, Wampfler JA,
Marks RS, Edell ES, Thibodeau S, Adjei AA, Jett J and Deschamps C:
Clinical features of 5,628 primary lung cancer patients: Experience
at mayo clinic from 1997 to 2003. Chest. 128:452–462. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Fridman JS and Lowe SW: Control of
apoptosis by p53. Oncogene. 22:9030–9040. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Fukasawa K, Wiener F, Woude GF Vande and
Mai S: Genomic instability and apoptosis are frequent in p53
deficient young mice. Oncogene. 15:1295–1302. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cheng Y and Lotan R: Molecular cloning and
characterization of a novel retinoic acid-inducible gene that
encodes a putative G protein-coupled receptor. J Biol Chem.
273:35008–35015. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tao Q, Fujimoto J, Men T, Ye X, Deng J,
Lacroix L, Clifford JL, Mao L, Van Pelt CS, Lee JJ, et al:
Identification of the retinoic acid-inducible Gprc5a as a new lung
tumor suppressor gene. J Natl Cancer Inst. 99:1668–1682. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ye X, Tao Q, Wang Y, Cheng Y and Lotan R:
Mechanisms underlying the induction of the putative human tumor
suppressor GPRC5A by retinoic acid. Cancer Biol Ther. 8:951–962.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kadara H, Fujimoto J, Men T, Ye X, Lotan
D, Lee JS and Lotan R: A Gprc5a tumor suppressor loss of expression
signature is conserved, prevalent, and associated with survival in
human lung adenocarcinomas. Neoplasia. 12:499–505. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Mogi A and Kuwano H: TP53 mutations in
nonsmall cell lung cancer. J Biomed Biotechnol. 2011:5839292011.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wu Q, Ding W, Mirza A, Van Arsdale T, Wei
I, Bishop WR, Basso A, McClanahan T, Luo L, Kirschmeier P, et al:
Integrative genomics revealed RAI3 is a cell growth-promoting gene
and a novel P53 transcriptional target. J Biol Chem.
280:12935–12943. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li S, Huang S and Peng SB: Overexpression
of G protein-coupled receptors in cancer cells: Involvement in
tumor progression. Int J Oncol. 27:1329–1339. 2005.PubMed/NCBI
|
|
12
|
Fujimoto J, Kadara H, Men T, van Pelt C,
Lotan D and Lotan R: Comparative functional genomics analysis of
NNK tobacco-carcinogen induced lung adenocarcinoma development in
Gprc5a-knockout mice. PLoS One. 5:e118472010. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Barta P, Van Pelt C, Men T, Dickey BF,
Lotan R and Moghaddam SJ: Enhancement of lung tumorigenesis in a
Gprc5a Knockout mouse by chronic extrinsic airway inflammation. Mol
Cancer. 11:42012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Fujimoto J, Kadara H, Garcia MM, Kabbout
M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, et al:
G-protein coupled receptor family C, group 5, member A (GPRC5A)
expression is decreased in the adjacent field and normal bronchial
epithelia of patients with chronic obstructive pulmonary disease
and non-small-cell lung cancer. J Thorac Oncol. 7:1747–1754. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Nagahata T, Sato T, Tomura A, Onda M,
Nishikawa K and Emi M: Identification of RAI3 as a therapeutic
target for breast cancer. Endocr Relat Cancer. 12:65–73. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Chen X, Wong JY, Wong P and Radany EH:
Low-dose valproic acid enhances radiosensitivity of prostate cancer
through acetylated p53-dependent modulation of mitochondrial
membrane potential and apoptosis. Mol Cancer Res. 9:448–461. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lakin ND and Jackson SP: Regulation of p53
in response to DNA damage. Oncogene. 18:7644–7655. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Nowsheen S and Yang ES: The intersection
between DNA damage response and cell death pathways. Exp Oncol.
34:243–254. 2012.PubMed/NCBI
|
|
20
|
Hirano M, Zang L, Oka T, Ito Y, Shimada Y,
Nishimura Y and Tanaka T: Novel reciprocal regulation of cAMP
signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A
gene expression. Biochem Biophys Res Commun. 351:185–191. 2006.
View Article : Google Scholar : PubMed/NCBI
|
