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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2017 Volume 16 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Role of hypoxia‑mediated cellular prion protein functional change in stem cells and potential application in angiogenesis (Review)

Seung Pil Yun, Yong‑Seok Han, Jun Hee Lee, Yeo Min Yoon, Chul Won Yun, Peter Rhee, Sang Hun Lee
Pages: 5747-5751
Published online on: 29 August 2017

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Article Open Access

Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development

Kosuke Takeda, Ryuichi Noguchi, Mitsuteru Kitade, Tadashi Namisaki, Kei Moriya, Hideto Kawaratani, Yasushi Okura, Kosuke Kaji, Yosuke Aihara, Akitoshi Douhara, Norihisa Nishimura, Yasuhiko Sawada, Kenichiro Seki, Hitoshi Yoshiji
Pages: 5752-5758
Published online on: 24 August 2017

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Article

Aloin promotes A549 cell apoptosis via the reactive oxygen species‑mitogen activated protein kinase signaling pathway and p53 phosphorylation

Li Wan, Lin Zhang, Kai Fan, Jianjun Wang
Pages: 5759-5768
Published online on: 29 August 2017

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Article Open Access

Endocrine therapy inhibits proliferation and migration, promotes apoptosis and suppresses survivin protein expression in colorectal cancer cells

Qing‑Jian Ou, Xiao‑Jun Wu, Jian‑Hong Peng, Rong‑Xin Zhang, Zhen‑Hai Lu, Wu Jiang, Lin Zhang, Zhi‑Zhong Pan, De‑Sen Wan, Yu‑Jing Fang
Pages: 5769-5778
Published online on: 28 August 2017

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Article Open Access

In vitro and in vivo antitumor effects of chloroquine on oral squamous cell carcinoma

Lihua Jia, Juan Wang, Tong Wu, Jinan Wu, Junqi Ling, Bin Cheng
Pages: 5779-5786
Published online on: 23 August 2017

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Article Open Access

Endoplasmic reticulum stress induced by lipopolysaccharide is involved in the association between inflammation and autophagy in INS‑1 cells

Han Liu, Jia‑Jing Yin, Ming‑Ming Cao, Guo‑Dong Liu, Ying Su, Yan‑Bo Li
Pages: 5787-5792
Published online on: 24 August 2017

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Article Open Access

Association of BAFF with PI3K/Akt/mTOR signaling in lupus nephritis

Fengmei Ge, Fangfang Wang, Xiuqing Yan, Zhao Li, Xuebin Wang
Pages: 5793-5798
Published online on: 28 August 2017

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Article Open Access

Anti‑angiogenesis gene therapy for hepatocellular carcinoma via systemic injection of mesenchymal stem cells engineered to secrete soluble Flt‑1

Guanglin Li, Fei Miao, Jinhai Zhu, Yanling Chen
Pages: 5799-5806
Published online on: 22 August 2017

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Article Open Access

Electroacupuncture serum inhibits TNF‑α‑mediated chondrocyte inflammation via the Ras‑Raf‑MEK1/2‑ERK1/2 signaling pathway

Houhuang Chen, Xiang Shao, Li Li, Chunsong Zheng, Xin Xu, Xiue Hong, Xihai Li, Mingxia Wu
Pages: 5807-5814
Published online on: 28 August 2017

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Article Open Access

MicroRNA‑497 inhibits cellular proliferation, migration and invasion of papillary thyroid cancer by directly targeting AKT3 Retraction in /10.3892/mmr.2022.12843

Juhua Zhuang, Ying Ye, Guoyu Wang, Jing Ni, Saifei He, Cuihua Hu, Wei Xia, Zhongwei Lv
Pages: 5815-5822
Published online on: 24 August 2017

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Article Open Access

Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome‑wide association study

Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka
Pages: 5823-5832
Published online on: 23 August 2017

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Article Open Access

AKT2 is involved in the IL‑17A‑mediated promotion of differentiation and calcification of murine preosteoblastic MC3T3‑E1 cells

Jing‑Yi Tan, Li‑Hong Lei, Xiao‑Tao Chen, Pei‑Hui Ding, Yan‑Min Wu, Li‑Li Chen
Pages: 5833-5840
Published online on: 22 August 2017

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Article Open Access

FGFR2 mutations and associated clinical observations in two Chinese patients with Crouzon syndrome

Ying Lin, Hongbin Gao, Siming Ai, Jacob V.P. Eswarakumar, Yi Zhu, Chuan Chen, Tao Li, Bingqian Liu, Hongye Jiang, Yuhua Liu, Yonghao Li, Qingxiu Wu, Haichun Li, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Lin Lu
Pages: 5841-5846
Published online on: 29 August 2017

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Article Open Access

Short‑term vagus nerve stimulation reduces myocardial apoptosis by downregulating microRNA‑205 in rats with chronic heart failure

Yanhua Xuan, Shuangshuang Liu, Yan Li, Jing Dong, Jiaying Luo, Tao Liu, Yuanzhe Jin, Zhijun Sun
Pages: 5847-5854
Published online on: 23 August 2017

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Article Open Access

Tacrolimus downregulates inflammation by regulating pro‑/anti‑inflammatory responses in LPS‑induced keratitis

Yifeng Yu, Jing Zhong, Lulu Peng, Bowen Wang, Saiqun Li, Haixiang Huang, Yuqing Deng, Henan Zhang, Ruhui Yang, Changyun Wang, Jin Yuan
Pages: 5855-5862
Published online on: 24 August 2017

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Article Open Access

Analysis of gene expression profiling variations induced by hsa‑miR‑145‑5p‑overexpression in laryngeal squamous cell carcinoma cell line Tu‑177

Yongxia Ding, Yongyan Wu, Wei Gao, Chunming Zhang, Qinli Zhao, Huina Guo, Xukuan Qu, Shuxin Wen, Binquan Wang
Pages: 5863-5870
Published online on: 24 August 2017

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Article Open Access

Comprehensive bioinformatics analysis of the mRNA profile of PLCE1 knockdown in esophageal squamous cell carcinoma

Xiaobin Cui, Huahua Xin, Hao Peng, Yunzhao Chen
Pages: 5871-5880
Published online on: 22 August 2017

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Article Open Access

The role of gene polymorphisms in endometriosis

Michail Matalliotakis, Maria I. Zervou, Charoula Matalliotaki, Nilufer Rahmioglu, George Koumantakis, Ioannis Kalogiannidis, Ioannis Prapas, Krina Zondervan, Demetrios A. Spandidos, Ioannis Matalliotakis, George N. Goulielmos
Pages: 5881-5886
Published online on: 29 August 2017

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Article Open Access

Differentiation of cardiomyocytes from amniotic fluid‑derived mesenchymal stem cells by combined induction with transforming growth factor β1 and 5‑azacytidine

Shan Jiang, Song Zhang
Pages: 5887-5893
Published online on: 28 August 2017

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Article Open Access

Detection of circulating tumor cells by reverse transcription‑quantitative polymerase chain reaction and magnetic activated cell sorting in the peripheral blood of patients with hepatocellular carcinoma

Limin Guo, Donghai Xu, Yan Lu, Jirun Peng, Li Jiang
Pages: 5894-5900
Published online on: 28 August 2017

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Article Open Access

Mechanical loading modulates heterotopic ossification in calcific tendinopathy through the mTORC1 signaling pathway

Guorong Chen, Huaji Jiang, Xinggui Tian, Jiajun Tang, Xiaochun Bai, Zhongmin Zhang, Liang Wang
Pages: 5901-5907
Published online on: 29 August 2017

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Article Open Access

Tanshinone IIA induces apoptosis via inhibition of Wnt/β‑catenin/MGMT signaling in AtT‑20 cells

Zong‑Yang Li, Guo‑Dong Huang, Lei Chen, Ce Zhang, Bao‑Dong Chen, Qing‑Zhong Li, Xiang Wang, Xie‑Jun Zhang, Wei‑Ping Li
Pages: 5908-5914
Published online on: 22 August 2017

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Article Open Access

Involvement of RBP4 in all‑trans retinoic acid induced cleft palate

Shiyi Dong, Yadong Zhang, Hongzhang Huang
Pages: 5915-5923
Published online on: 22 August 2017

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Article Open Access

Effects of erythropoietin and methylprednisolone on AQP4 expression in astrocytes

Changchao Wang, Youjia Xu, Yadong Huang, Yan Huang
Pages: 5924-5930
Published online on: 22 August 2017

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Article Open Access

Dynamic expression analysis of armc10, the homologous gene of human GPRASP2, in zebrafish embryos

Chunyu Liu, Changsong Lin, Jun Yao, Qinjun Wei, Guangqian Xing, Xin Cao
Pages: 5931-5937
Published online on: 24 August 2017

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Article Open Access

Neuroprotective effects of hydrogen sulfide on sodium azide‑induced autophagic cell death in PC12 cells

Haiyan Shan, Yang Chu, Pan Chang, Lijun Yang, Yi Wang, Shaohua Zhu, Mingyang Zhang, Luyang Tao
Pages: 5938-5946
Published online on: 25 August 2017

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Article Open Access

LAMP3 promotes the invasion of osteosarcoma cells via SPP1 signaling

Yu Li, Wei Du, Jian Han, Junbo Ge
Pages: 5947-5953
Published online on: 24 August 2017

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Article Open Access

Investigating the mechanisms of papillary thyroid carcinoma using transcriptome analysis

Jie Qiu, Wenwei Zhang, Qingsheng Xia, Fuxue Liu, Shuwei Zhao, Kailing Zhang, Min Chen, Chuanshan Zang, Ruifeng Ge, Dapeng Liang, Yan Sun
Pages: 5954-5964
Published online on: 24 August 2017

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Article Open Access

Tumor necrosis factor‑α and interleukin‑6 suppress microRNA‑1275 transcription in human adipocytes through nuclear factor‑κB

Yu‑Feng Zhou, Zi‑Yi Fu, Xiao‑Hui Chen, Yan Cui, Chen‑Bo Ji, Xi‑Rong Guo
Pages: 5965-5971
Published online on: 29 August 2017

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Article Open Access

Mdivi‑1 attenuates sodium azide‑induced apoptosis in H9c2 cardiac muscle cells

Xuehua Xu, Chengliang Luo, Zhixiang Zhang, Jun Hu, Xiangting Gao, Yuanyi Zuo, Yun Wang, Shaohua Zhu
Pages: 5972-5978
Published online on: 24 August 2017

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Article Open Access

Lactobacillus plantarum LP‑Onlly alters the gut flora and attenuates colitis by inducing microbiome alteration in interleukin‑10 knockout mice

Hongqi Chen, Yang Xia, Sibo Zhu, Jun Yang, Jing Yao, Jianzhong Di, Yong Liang, Renyuan Gao, Wen Wu, Yongzhi Yang, Chenzhang Shi, Desheng Hu, Huanlong Qin, Zhigang Wang
Pages: 5979-5985
Published online on: 24 August 2017

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Article Open Access

Ultrasound and magnetic resonance molecular imaging of atherosclerotic neovasculature with perfluorocarbon magnetic nanocapsules targeted against vascular endothelial growth factor receptor 2 in rats

Hua Chen, Lianglong Chen, Rongxi Liang, Jin Wei
Pages: 5986-5996
Published online on: 22 August 2017

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Article Open Access

Association of a reduction of G‑protein coupled receptor 30 expression and the pathogenesis of preeclampsia

Xiang Feng, Liyuan Zhou, Xun Mao, Chao Tong, Xuyang Chen, Diqi Zhao, Philip N. Baker, Yinyin Xia, Hua Zhang
Pages: 5997-6003
Published online on: 23 August 2017

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Article Open Access

Alterations in the long non‑coding RNA transcriptome in mesangial cells treated with aldosterone in vitro

Gaoting Qu, Huimin Shi, Bin Wang, Shanwen Li, Aiqing Zhang, Weihua Gan
Pages: 6004-6012
Published online on: 22 August 2017

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Article Open Access

Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice Corrigendum in /10.3892/mmr.2018.9116

Bing He, Xiaoou Li, Tuo Hu, Wenjing Lian, Mingxia Zhang
Pages: 6013-6019
Published online on: 22 August 2017

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Article Open Access

Staphylococcus aureus Protein A induces osteoclastogenesis via the NF‑κB signaling pathway

Li‑Rong Ren, Hai Wang, Xiao‑Qing He, Mu‑Guo Song, Xue‑Qiu Chen, Yong‑Qing Xu
Pages: 6020-6028
Published online on: 22 August 2017

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Article Open Access

Molecular characterization of a pedigree carrying the hypertension‑associated mitochondrial tRNAGln T4363C mutation

Lei Wang, Zhibing Dong, Wenhui Lin, Ranran Gao, Caiming Chen, Jinzhong Xu
Pages: 6029-6033
Published online on: 28 August 2017

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Article Open Access

Interferon regulatory factor 4 (IRF4) is overexpressed in human non‑small cell lung cancer (NSCLC) and activates the Notch signaling pathway

Yajuan Qian, Ziyan Du, Yufei Xing, Tong Zhou, Ting Chen, Minhua Shi
Pages: 6034-6040
Published online on: 22 August 2017

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Article Open Access

Subcutaneous injection of dendritic cells aggravates atherosclerosis in ApoE‑knockout mice by activation of TLR4

Zhishuai Ye, Mingyu Jin, Shujing Wang, Jianing Zhang, Xiantao Song, Rongchong Huang
Pages: 6041-6049
Published online on: 23 August 2017

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Article Open Access

Effect of silencing the T‑Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells

Wen‑Liang Du, Qian Fang, Yue Chen, Jing‑Wei Teng, Yong‑Shuang Xiao, Ping Xie, Bo Jin, Jun‑Qi Wang
Pages: 6050-6058
Published online on: 24 August 2017

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Article Open Access

Cardiovascular risk assessment in osteoporotic patients using osteoprotegerin as a reliable predictive biochemical marker

Carmen G. Barbu, Andreea L. Arsene, Suzana Florea, Alice Albu, Anca Sirbu, Sorina Martin, Alina C. Nicolae, George T.A. Burcea‑Dragomiroiu, Daniela E. Popa, Bruno S. Velescu, Ion B. Dumitrescu, Niculina Mitrea, Doina Draganescu, Dumitru Lupuliasa, Demetrios A. Spandidos, Aristides M. Tsatsakis, Cristina M. Dragoi, Simona Fica
Pages: 6059-6067
Published online on: 28 August 2017

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Article Open Access

Differentiation of mesenchymal stem cells from human amniotic fluid to cardiomyocyte‑like cells

Runchana Markmee, Sirinda Aungsuchawan, Suteera Narakornsak, Waleephan Tancharoen, Kanokkarn Bumrungkit, Nataporn Pangchaidee, Peraphan Pothacharoen, Chaniporn Puaninta
Pages: 6068-6076
Published online on: 23 August 2017

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Article Open Access

Genetic association study in a three-generation family with seven members with endometriosis

Michail Matalliotakis, Maria I. Zervou, Charoula Matalliotaki, Aydin Arici, Demetrios A. Spandidos, Ioannis Matalliotakis, George N. Goulielmos
Pages: 6077-6080
Published online on: 23 August 2017

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Article Open Access

LPS‑induced downregulation of microRNA‑204/211 upregulates and stabilizes Angiopoietin‑1 mRNA in EA.hy926 endothelial cells

Yijun Zhang, Caixia Gan, Jiangbo Zhang, Dong Chen
Pages: 6081-6087
Published online on: 30 August 2017

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Article

TSA increases C/EBP‑α expression by increasing its lysine acetylation in hepatic stellate cells

Li‑Li Tao, Di Ding, Wei‑Hua Yin, Ji‑Ying Peng, Chen‑Jian Hou, Xiu‑Ping Liu, Yao‑Li Chen
Pages: 6088-6093
Published online on: 24 August 2017

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Article

Histone deacetylase inhibitor quisinostat activates caspase signaling and upregulates p53 acetylation to inhibit the proliferation of HepG2 cells

Fengshan Li, Tiegong Wang, Zhenyong Wang, Xiongfei Chen, Ruhai Liu
Pages: 6094-6101
Published online on: 24 August 2017

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Article

Effect of the hepatitis B virus S‑ecdCD40L vaccine therapy in HBV transgenic mice: A vaccine‑induced activation of antigen presenting dendritic cells

Huaqin Guan, Songsong Lan, Jinming Wu, Binbin Tang, Yin Xu
Pages: 6102-6108
Published online on: 22 August 2017

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Article

Anti‑inflammatory actions of gabapentin and pregabalin on the substance P‑induced mitogen‑activated protein kinase activation in U373 MG human glioblastoma astrocytoma cells

Keisuke Yamaguchi, Seiichiro Kumakura, Akimasa Someya, Masako Iseki, Eiichi Inada, Isao Nagaoka
Pages: 6109-6115
Published online on: 28 August 2017

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Article

Aminoguanidine exhibits an inhibitory effect on β‑amyloid‑induced damage in F98 glioma cells

Tao Chen, Xiao‑Li Sun, Xi‑Ai Yang, Jing‑Jing Shi, Yi Liu, Jia‑Ming Gong
Pages: 6116-6121
Published online on: 29 August 2017

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Article

Downregulation of TM7SF4 inhibits cell proliferation and metastasis of A549 cells through regulating the PI3K/AKT/mTOR signaling pathway

Xudong Yang, Xiaoming Song, Xiaohang Wang, Xiangyan Liu, Zhongmin Peng
Pages: 6122-6127
Published online on: 22 August 2017

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Article

Hydrogen peroxide promotes the expression of angiopoietin like 4 in RAW264.7 macrophages via MAPK pathways

Nan Liu, Changxia Cui, Yue Sun, Feng Zhang, Shuya Wang, Guohai Su, Xiaojun Cai
Pages: 6128-6133
Published online on: 28 August 2017

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Article

Anthocyanin‑rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis

Naoki Nanashima, Kayo Horie, Mitsuru Chiba, Manabu Nakano, Hayato Maeda, Toshiya Nakamura
Pages: 6134-6141
Published online on: 29 August 2017

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Article

Epigallocatechin‑3‑gallate protects from high glucose induced podocyte apoptosis via suppressing endoplasmic reticulum stress

Chunhong Xiang, Xiaoyan Xiao, Bei Jiang, Mengkun Zhou, Yidan Zhang, Hui Li, Zhao Hu
Pages: 6142-6147
Published online on: 29 August 2017

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Article

Mechanisms of N‑acetylcysteine in reducing monocrotaline‑induced pulmonary hypertension in rats: Inhibiting the expression of Nox1 in pulmonary vascular smooth muscle cells

Wencheng Yu, Weina Ji, Liyun Mi, Chen Lin
Pages: 6148-6155
Published online on: 22 August 2017

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Article

Overexpression of Bmi‑1 promotes epithelial‑mesenchymal transition in CD133+Hep G2 cells

Zefeng Zhang, Qiyi Wang, Xiaoling Bu, Chuangqiang Zhang, Hao Chen, Weihong Sha, Wanwei Liu
Pages: 6156-6161
Published online on: 24 August 2017

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Article

Beneficial effect of 20‑hydroxyecdysone exerted by modulating antioxidants and inflammatory cytokine levels in collagen‑induced arthritis: A model for rheumatoid arthritis

You Sun, De‑Li Zhao, Zi‑Xuan Liu, Xue‑Hui Sun, Yang Li
Pages: 6162-6169
Published online on: 29 August 2017

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Article

Conditioned medium from tonsil‑derived mesenchymal stem cells promotes adiponectin production

Yu‑Hee Kim, Kyung‑Ah Cho, Minhwa Park, Julie A. Webster, So‑Youn Woo, Kyung‑Ha Ryu
Pages: 6170-6177
Published online on: 23 August 2017

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Article

Construction of a chalcone reductase expression vector and transformation of soybean plants

Nan Wu, Pi‑Wu Wang, Nan Lin, Shi Lu, Yong‑Qi Feng, Jie Rong, Zhuo Zhang, Jing Qu
Pages: 6178-6183
Published online on: 29 August 2017

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Article

Protective effects of DL‑3‑n‑butylphthalide in the lipopolysaccharide‑induced mouse model of Parkinson's disease

Mu‑Jun Jiang, Yu‑Hua Chen, Li Li, Li Xu, Hao Liu, Xiao‑Long Qu, Juan‑Juan Xu, Bo‑Bo Ge, Hong‑Dang Qu
Pages: 6184-6189
Published online on: 24 August 2017

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Article

Valproic acid inhibits epithelial‑mesenchymal transition in renal cell carcinoma by decreasing SMAD4 expression

Shaowei Mao, Guoliang Lu, Xiaopeng Lan, Chuanwei Yuan, Wei Jiang, Yougen Chen, Xunbo Jin, Qinghua Xia
Pages: 6190-6199
Published online on: 29 August 2017

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Article

Jueming prescription and its ingredients, semen cassiae and Rhizoma Curcumae Longae, stimulate lipolysis and enhance the phosphorylation of hormone‑sensitive lipase in cultured rat white adipose tissue

Yue Zhang, Jiaojiao Li, Xiuying Wen
Pages: 6200-6207
Published online on: 22 August 2017

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Article

Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway

Min Gao, Tianlei Chen, Lin Wu, Xiufen Zhao, Huijuan Mao, Changying Xing
Pages: 6208-6213
Published online on: 22 August 2017

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Article

DADLE improves hepatic ischemia/reperfusion injury in mice via activation of the Nrf2/HO‑1 pathway

Yi Zhou, Jing Zhang, Biao Lei, Wenjin Liang, Jianhua Gong, Chuanxiang Zhao, Jidong Yu, Xuan Li, Bo Tang, Shengguang Yuan
Pages: 6214-6221
Published online on: 29 August 2017

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Case Report

Genotype/phenotype analysis in a male patient with partial trisomy 4p and monosomy 20q due to maternal reciprocal translocation (4;20): A case report

Dong Wu, Hui Zhang, Qiaofang Hou, Hongdan Wang, Tao Wang, Shixiu Liao
Pages: 6222-6227
Published online on: 29 August 2017

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Article

The protective effect of berberine hydrochloride on LPS‑induced osteoclastogenesis through inhibiting TRAF6‑Ca2+‑calcineurin‑NFATcl signaling pathway

Fei Ye, Qingzhong Zhou, Long Tian, Fei Lei, Daxiong Feng
Pages: 6228-6233
Published online on: 23 August 2017

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Article

Association between endothelin‑1 and fibromyalgia syndrome

Seong‑Su Nah, Hwayoung Lee, Yeongseon Hong, Jiyun Im, Hansol Won, Sung‑Hae Chang, Hyung‑Ki Kim, Jun‑Tack Kwon, Hak‑Jae Kim
Pages: 6234-6239
Published online on: 29 August 2017

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Article

Retinoic acid ameliorates photoaged skin through RAR‑mediated pathway in mice

Zhangjun Li, Xinwu Niu, Shengxiang Xiao, Huiqun Ma
Pages: 6240-6247
Published online on: 23 August 2017

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Article

Anti‑allergic action of bacillus Calmette‑Guerin extract in experimental mast cell‑mediated anaphylactic models

Mingli Sun, Yong Wang, Haishan Zhao, Weifan Yao, Xiaosong Yu
Pages: 6248-6254
Published online on: 29 August 2017

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Article

Hydrogen sulfide facilities production of nitric oxide via the Akt/endothelial nitric oxide synthases signaling pathway to protect human umbilical vein endothelial cells from injury by angiotensin II

Jiasen Cui, Shunjiu Zhuang, Shaohong Qi, Li Li, Junwen Zhou, Wan Zhang, Yun Zhao, Ning Qi, Yangjun Yin, Lu Huang
Pages: 6255-6261
Published online on: 22 August 2017

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Article

Puerarin promotes the viability and differentiation of MC3T3‑E1 cells by miR‑204‑regulated Runx2 upregulation

Xiu‑Qin Zhan, Xiang‑Wei Zeng, Ying‑Ying Zhang, Qian Feng, Feng‑Ming Zhao, Ze‑Qun Jiang, Chao Sun
Pages: 6262-6268
Published online on: 29 August 2017

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Article

Nicotine induces H9C2 cell apoptosis via Akt protein degradation

Chong Huang, Xiong Guo, Huishou Zhao, Rui An, Kun Lian, Xiaomeng Zhang, Jinglong Zhang, Feng Yan, Huaning Xie, Shan Wang, Ling Tao
Pages: 6269-6275
Published online on: 22 August 2017

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Article

Proteomic profile‑based screening of potential protein biomarkers in the urine of patients with nephrotic syndrome

Yu Wang, Chunxia Zheng, Xia Wang, Ke Zuo, Zhihong Liu
Pages: 6276-6284
Published online on: 22 August 2017

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Article

Articular cartilage degradation is prevented by tanshinone IIA through inhibiting apoptosis and the expression of inflammatory cytokines

Pei‑Tong Jia, Xing‑Lin Zhang, Hai‑Ning Zuo, Xing Lu, Lin Li
Pages: 6285-6289
Published online on: 23 August 2017

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Article

GATA4 is highly expressed in childhood acute lymphoblastic leukemia, promotes cell proliferation and inhibits apoptosis by activating BCL2 and MDM2

Qiuguo Han, Xin Xu, Jing Li, Jinggang Wang, Li Bai, Aihong Wang, Wei Wang, Bo Zhang
Pages: 6290-6298
Published online on: 28 August 2017

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Article

Antitumor activity of 2‑[(2E)‑3,7‑dimethyl‑2,6‑octadienyl]‑6‑methyl‑2,5‑cyclohexadiene‑1,4‑dione isolated from the aerial part of Atractylodes macrocephala in hepatocellular carcinoma

Lei Li, Rui Zhao, Ying Li, Wen‑Hui Wang
Pages: 6299-6305
Published online on: 29 August 2017

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Article

Exogenous leptin protects rat models of sodium taurocholate‑induced severe acute pancreatitis through endocrinal and immunological pathways

Haiyu Qi, Qin Lu, Chenghong Yin, Hongli Xiao, Yan Wen, Shuwen Zhang, Qu Cui, Wei Yang
Pages: 6306-6312
Published online on: 22 August 2017

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Article

Stable silencing of TIPE2 reduced the Poly I:C‑induced apoptosis in THP‑1 cells

Jieshu Jiang, Shanshan Wang, Jingjing Fang, Yi Xu, Li Tong, Xiaolei Ye, Wu Zhou
Pages: 6313-6319
Published online on: 25 August 2017

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Article

Betulinic acid prevents high glucose‑induced expression of extracellular matrix protein in cardiac fibroblasts by inhibiting the TGF‑β1/Smad signaling pathway

Ling Jiang, Feng‑Xia Chen, Shu‑Ting Zang, Qiao‑Fang Yang
Pages: 6320-6325
Published online on: 22 August 2017

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Article

Expression of CD19+CD24highCD38high B cells, IL‑10 and IL‑10R in peripheral blood from patients with systemic lupus erythematosus

Tao Wang, Zhijun Li, Xingfu Li, Linjie Chen, Hao Zhao, Chao Jiang, Lijun Song
Pages: 6326-6333
Published online on: 29 August 2017

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Article

Effect of continuous positive airway pressure therapy on inflammatory cytokines and atherosclerosis in patients with obstructive sleep apnea syndrome

Fa Jin, Jiannan Liu, Xiuwei Zhang, Wei Cai, Yuqiong Zhang, Wei Zhang, Jian Yang, Gan Lu, Xilong Zhang
Pages: 6334-6339
Published online on: 30 August 2017

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Article

Effects of an irinotecan derivative, ZBH‑1208, on the immune system in a mouse model of brain tumor and its antitumor mechanism

Yuzuo Hui, Zhiyu Gao, Songtao Ren, Yunhua Wang, Xiaoping Ma
Pages: 6340-6345
Published online on: 28 August 2017

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Article

Tumor necrosis factor‑α‑induced protein‑8 like 2 regulates lipopolysaccharide‑induced rat rheumatoid arthritis immune responses and is associated with Rac activation and interferon regulatory factor 3 phosphorylation

Chunyan Shi, Yue Wang, Guohong Zhuang, Zhongquan Qi, Yanping Li, Ping Yin
Pages: 6346-6353
Published online on: 22 August 2017

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Article

Myricitrin inhibits vascular adhesion molecule expression in TNF‑α‑stimulated vascular smooth muscle cells

Li‑Jie Yan, Hai‑Tao Yang, Hong‑Yan Duan, Jin‑Tao Wu, Peng Qian, Xian‑Wei Fan, Shanling Wang
Pages: 6354-6359
Published online on: 22 August 2017

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Article

MicroRNA‑302a inhibits cell proliferation and invasion, and induces cell apoptosis in hepatocellular carcinoma by directly targeting VEGFA

Chenglin Qin, Wenzhang Zha, Rengen Fan, Huimin Ding, Yonghua Xu, Chen Wang
Pages: 6360-6367
Published online on: 22 August 2017

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Article

siRNA‑mediated knockdown of T‑bet and RORγt contributes to decreased inflammation in pre‑eclampsia

Jing Wang, Zhu Qing Wen, Xiao‑Yan Cheng, Tao Yu Mei, Zhi‑Fang Chen, Liang‑Xiang Su
Pages: 6368-6375
Published online on: 24 August 2017

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Article

Amplification by (‑)‑epigallocatechin gallate of prostaglandin F2α‑stimulated synthesis of osteoprotegerin in osteoblasts

Go Sakai, Takanobu Otsuka, Kazuhiko Fujita, Shingo Kainuma, Gen Kuroyanagi, Tetsu Kawabata, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 6376-6381
Published online on: 24 August 2017

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Article

Lung cancer suppressor gene GPRC5A mediates p53 activity in non‑small cell lung cancer cells in vitro

Er Jin, Wenzhe Wang, Mengdie Fang, Limin Wang, Kan Wu, Yemei Zhang, Shirong Zhang, Shenglin Ma
Pages: 6382-6388
Published online on: 23 August 2017

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Article

Effects of Artesunate prevent nephritis via the Toll‑like receptor 4/nuclear factor‑κB signaling pathway in rats

Rong Jun Wan, Yue Hong Li
Pages: 6389-6395
Published online on: 24 August 2017

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Article

Analysis of the Panax ginseng stem/leaf transcriptome and gene expression during the leaf expansion period

Shichao Liu, Meichen Liu, Siming Wang, Yanling Lin, Hui Zhang, Qun Wang, Yu Zhao
Pages: 6396-6404
Published online on: 29 August 2017

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Article

Downregulated SOCS1 expression activates the JAK1/STAT1 pathway and promotes polarization of macrophages into M1 type

Yan‑Bing Liang, Hao Tang, Zhi‑Bin Chen, Li‑Jin Zeng, Jing‑Guo Wu, Wen Yang, Zhen‑Yu Li , Zhong‑Fu Ma
Pages: 6405-6411
Published online on: 29 August 2017

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Article

Screening and validation of differentially expressed extracellular miRNAs in acute pancreatitis

Shishuai Meng, Hao Wang, Dongbo Xue, Weihui Zhang
Pages: 6412-6418
Published online on: 28 August 2017

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Article

MicroRNA‑543 inhibits proliferation, invasion and induces apoptosis of glioblastoma cells by directly targeting ADAM9

Tao Ji, Xiejun Zhang, Weiping Li
Pages: 6419-6427
Published online on: 23 August 2017

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Article

MicroRNA‑382 inhibits cell proliferation and invasion of retinoblastoma by targeting BDNF‑mediated PI3K/AKT signalling pathway

Dan Song, Jiandong Diao, Yongjing Yang, Yahong Chen
Pages: 6428-6436
Published online on: 29 August 2017

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Review Open Access

Targeting strategies of adenovirus‑mediated gene therapy and virotherapy for prostate cancer (Review)

Zhonglin Cai, Haidi Lv, Wenjuan Cao, Chuan Zhou, Qiangzhao Liu, Hui Li, Fenghai Zhou
Pages: 6443-6458
Published online on: 13 September 2017

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Review Open Access

Cell cycle and pluripotency: Convergence on octamer‑binding transcription factor 4 (Review)

Shiqi She, Qucheng Wei, Bo Kang, Ying‑Jie Wang
Pages: 6459-6466
Published online on: 13 September 2017

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Review

Taurine‑upregulated gene 1: A vital long non‑coding RNA associated with cancer in humans (Review)

Wen‑Yu Wang, Yan‑Fen Wang, Pei Ma, Tong‑Peng Xu, Yong‑Qian Shu
Pages: 6467-6471
Published online on: 12 September 2017

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Review

Interactions between hematopoietic progenitor kinase 1 and its adaptor proteins (Review)

Qing Zhang, Shu Ding, Huilin Zhang
Pages: 6472-6482
Published online on: 13 September 2017

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Article Open Access

Effect of hyperoside on the apoptosis of A549 human non‑small cell lung cancer cells and the underlying mechanism

Yu Yang, Jicheng Tantai, Yifeng Sun, Chenxi Zhong, Zhigang Li
Pages: 6483-6488
Published online on: 11 September 2017

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Article Open Access

The role of fructose‑1,6‑bisphosphatase 1 in abnormal development of ovarian follicles caused by high testosterone concentration

Tao Liu, Han Zhao, Jianfeng Wang, Xin Shu, Yuan Gao, Xiaoli Mu, Fei Gao, Hongbin Liu
Pages: 6489-6498
Published online on: 12 September 2017

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Article Open Access

Colon cancer recurrence‑associated genes revealed by WGCNA co‑expression network analysis

Xiaofeng Zhai, Qingfeng Xue, Qun Liu, Yuyu Guo, Zhe Chen
Pages: 6499-6505
Published online on: 31 August 2017

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Article Open Access

MicroRNA‑21 increases cell viability and suppresses cellular apoptosis in non‑small cell lung cancer by regulating the PI3K/Akt signaling pathway Retraction in /10.3892/mmr.2020.11758

Tao Wang, Zhenyu Cai, Guolin Hong, Gangsen Zheng, Yu Huang, Shun Zhang, Jinhua Dai
Pages: 6506-6511
Published online on: 08 September 2017

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Article Open Access

Taurine alleviates lipopolysaccharide‑induced liver injury by anti‑inflammation and antioxidants in rats

Yueyan Liu, Feng Li, Li Zhang, Jianfeng Wu, Yanmei Wang, Hong Yu
Pages: 6512-6517
Published online on: 31 August 2017

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Article Open Access

Effect of early weaning on the expression of excitatory amino acid transporter 1 in the jejunum and ileum of piglets

Qiu‑Ju Wang, Yi‑Zhe Cui, Xiu‑Ying Zhang, Jing Su
Pages: 6518-6525
Published online on: 05 September 2017

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Article Open Access

Whole Wiskott‑Aldrich syndrome protein gene deletion identified by high throughput sequencing

Xiangling He, Runying Zou, Bing Zhang, Yalan You, Yang Yang, Xin Tian
Pages: 6526-6531
Published online on: 31 August 2017

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Article Open Access

Bioinformatics analysis of genetic variants of endoplasmic reticulum aminopeptidase 1 in ankylosing spondylitis

Xiaoli Wang, Jie Ma, Jianbing Ma, Yurong Wen, Liesu Meng, Hao Yang, Rui Zhang, Dingjun Hao
Pages: 6532-6543
Published online on: 31 August 2017

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Article Open Access

Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Pages: 6544-6551
Published online on: 05 September 2017

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Case Report Open Access

β‑thalassemia caused by compound heterozygous mutations and cured by bone marrow transplantation: A case report

Liusong Wu, Zhiyu Peng, Sen Lu, Mei Tan, Ying Rong, Runmei Tian, Yuhang Yang, Yan Chen, Jindong Chen
Pages: 6552-6557
Published online on: 12 September 2017

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Article Open Access

Effects of anticholinergic agent on miRNA profiles and transcriptomes in a murine model of allergic rhinitis

Minghua Hou, Wei Li, Zuozhong Xie, Jingang Ai, Bo Sun, Guolin Tan
Pages: 6558-6569
Published online on: 31 August 2017

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Article Open Access

Profiling of differentially expressed genes in adipose tissues of multiple symmetric lipomatosis

Ke Chen, Linghao Wang, Wenjun Yang, Changfa Wang, Gui Hu, Zhaohui Mo
Pages: 6570-6579
Published online on: 07 September 2017

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Article Open Access

Screening critical genes associated with malignant glioma using bioinformatics analysis

Yonggang Xu, Jie Wang, Yanbin Xu, Hong Xiao, Jianhua Li, Zhi Wang
Pages: 6580-6589
Published online on: 12 September 2017

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Article Open Access

Basic fibroblast growth factor increases IFT88 expression in chondrocytes

Daolu Zhan, Wei Xiang, Fengjing Guo, Yuanzheng Ma
Pages: 6590-6599
Published online on: 08 September 2017

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Article Open Access

A novel method for obtaining highly enriched Schwann cell populations from mature monkey nerves based on in vitro pre‑degeneration

Gangyang Wang, Zhengwen Ma, Lingling Cao, Guofeng Yan, Yang Wang, Yuqing Jin, Hua Shen, Yiping Zhang, Xiaoming Xu, Xuejin Chen, Zunli Shen
Pages: 6600-6607
Published online on: 05 September 2017

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Article Open Access

Differential miRNA expression profiles in human keratinocytes in response to protein kinase C inhibitor

Yang Liu, Liangchen Zhong, Dewu Liu, Hua Ye, Yuangui Mao, Yanghong Hu
Pages: 6608-6619
Published online on: 08 September 2017

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Article Open Access

Whole exome sequencing identifies FBN1 mutations in two patients with early‑onset type B aortic dissection

Qian Han, Wenwen Zhang, Changjian Liu, Min Zhou, Feng Ran, Long Yi, Xitai Sun, Zhao Liu
Pages: 6620-6625
Published online on: 31 August 2017

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Article Open Access

N‑acetylcysteine induces apoptosis via the mitochondria‑dependent pathway but not via endoplasmic reticulum stress in H9c2 cells

Yuyong Liu, Ke Liu, Nian Wang, Huali Zhang
Pages: 6626-6633
Published online on: 08 September 2017

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Article Open Access

Profilin‑1 contributes to cardiac injury induced by advanced glycation end‑products in rats

Dafeng Yang, Weiwei Liu, Liping Ma, Ya Wang, Jing Ma, Minna Jiang, Xu Deng, Fang Huang, Tianlun Yang, Meifang Chen
Pages: 6634-6641
Published online on: 08 September 2017

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Article Open Access

Synergistic protection of bone vasculature and bone mass by desferrioxamine in osteoporotic mice

Liang Wang, Peng Jia, Yu Shan, Yanming Hao, Xiao Wang, Yu Jiang, Ye Yuan, Qiaoqiao Du, Hui Zhang, Fan Yang, Wen Zhang, Mao Sheng, Youjia Xu
Pages: 6642-6649
Published online on: 08 September 2017

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Article Open Access

MicroRNA expression profiles and networks in placentas complicated with selective intrauterine growth restriction

Hong Wen, Lu Chen, Jing He, Jun Lin
Pages: 6650-6673
Published online on: 11 September 2017

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Article Open Access

Molecular mechanisms of pathogenesis in hepatocellular carcinoma revealed by RNA‑sequencing

Yao Liu, Zhe Yang, Feng Du, Qiao Yang, Jie Hou, Xiaohong Yan, Yi Geng, Yaning Zhao, Hua Wang
Pages: 6674-6682
Published online on: 11 September 2017

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Article Open Access

Expression of long non‑coding RNAs in human bone marrow mesenchymal stem cells co‑cultured with human amnion‑derived mesenchymal stem cells

Jingjing Wang, Jing Miao, Xin Meng, Ning Chen, Yuli Wang
Pages: 6683-6689
Published online on: 12 September 2017

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Article Open Access

High glucose and high insulin conditions promote MCF‑7 cell proliferation and invasion by upregulating IRS1 and activating the Ras/Raf/ERK pathway Corrigendum in /10.3892/mmr.2023.12967

Mei‑Lin Wei, Peng Duan, Zhi‑Ming Wang, Miao Ding, Ping Tu
Pages: 6690-6696
Published online on: 31 August 2017

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Article Open Access

Two novel peptides derived from Sinonovacula constricta inhibit the proliferation and induce apoptosis of human prostate cancer cells

Fangfang Huang, Guofang Ding, Zuisu Yang, Fangmiao Yu
Pages: 6697-6707
Published online on: 31 August 2017

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Article Open Access

CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway

Feng Tang, Shengjun Tang, Xiaolong Guo, Chao Yang, Ke Jia
Pages: 6708-6714
Published online on: 12 September 2017

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Article Open Access

Glycogen synthase kinase‑3β inhibitor reduces LPS‑induced acute lung injury in mice

Qi Ding, Gaoqin Liu, Yuanyuan Zeng, Jianjie Zhu, Zeyi Liu, Junhong Jiang, Jianan Huang
Pages: 6715-6721
Published online on: 12 September 2017

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Article Open Access

Simultaneous multi‑gene mutation screening using SNPscan in patients from ethnic minorities with nonsyndromic hearing‑impairment in Northwest China

Shi‑Hong Duan, Jian‑Li Ma, Xiao‑Long Yang, Yu‑Fen Guo
Pages: 6722-6728
Published online on: 07 September 2017

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Article Open Access

Tumor suppressor microRNA‑613 inhibits glioma cell proliferation, invasion and angiogenesis by targeting vascular endothelial growth factor A

Xiongwu Yu, Weimin Wang
Pages: 6729-6735
Published online on: 05 September 2017

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Article Open Access

Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritis

Fan Wang, Juan Wan, Qiuyan Li, Mingzhu Zhang, Qiaofeng Wan, Chen Ji, Haibo Li, Rongqing Liu, Mei Han
Pages: 6736-6742
Published online on: 07 September 2017

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Article Open Access

MicroRNA‑141 inhibits epithelial‑mesenchymal transition, and ovarian cancer cell migration and invasion

Qinghua Ye, Lei Lei, Lingyun Shao, Jing Shi, Jun Jia, Xiaowen Tong
Pages: 6743-6749
Published online on: 13 September 2017

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Article Open Access

Monocytic cell junction proteins serve important roles in atherosclerosis via the endoglin pathway

Lina Chen, Zhongliang Chen, Menghua Ge, Oushan Tang, Yinhong Cheng, Haoliang Zhou, Yu Shen, Fengming Qin
Pages: 6750-6756
Published online on: 08 September 2017

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Article Open Access

miR‑21 attenuates contrast‑induced renal cell apoptosis by targeting PDCD4

Kun Wang, Wei‑Jie Bei, Yuan‑Hui Liu, Hua‑Long Li, Shi‑Qun Chen, Kai‑Yang Lin, Zhi‑Ling Zhou, Ji‑Yan Chen, Yong Liu, Ning Tan
Pages: 6757-6763
Published online on: 05 September 2017

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Article Open Access

MicroRNA‑1288 promotes cell proliferation of human glioblastoma cells by repressing ubiquitin carboxyl‑terminal hydrolase CYLD expression

Jun Yin, Chengyin Weng, Jieke Ma, Fanfan Chen, Yecai Huang, Mei Feng
Pages: 6764-6770
Published online on: 13 September 2017

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Apolipoprotein A5 regulates intracellular triglyceride metabolism in adipocytes

Xiao‑Yan Zheng, Bi‑Lian Yu, Yu‑Fei Xie, Shui‑Ping Zhao, Chen‑Lu Wu
Pages: 6771-6779
Published online on: 11 September 2017

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Article Open Access

Genomic profile of oral squamous cell carcinomas with an adjacent leukoplakia or with an erythroleukoplakia that evolved after the treatment of primary tumor: A report of two cases

Ilda P. Ribeiro, Francisco Marques, Leonor Barroso, Joana Rodrigues, Francisco Caramelo, Joana B. Melo, Isabel M. Carreira
Pages: 6780-6786
Published online on: 05 September 2017

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Article Open Access

Discrimination of the heterogeneity of bone marrow‑derived dendritic cells

Jing Wang, Xiaomin Dai, Chiaching Hsu, Changsheng Ming, Ying He, Ji Zhang, Lai Wei, Ping Zhou, Cong‑Yi Wang, Jun Yang, Nianqiao Gong
Pages: 6787-6793
Published online on: 08 September 2017

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Vulnerability study of myelinated and unmyelinated nerve fibers in acute ocular hypertension in rabbit

Jiying Shen, Qiang Yang, Daoyi Yu, Jihong Wu, Yuanfang Zhu, Wenyi Guo
Pages: 6794-6802
Published online on: 12 September 2017

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Article Open Access

Identification of genes associated with castration‑resistant prostate cancer by gene expression profile analysis

Chui Guo Huang, Feng Xi Li, Song Pan, Chang Bao Xu, Jun Qiang Dai, Xing Hua Zhao
Pages: 6803-6813
Published online on: 13 September 2017

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Article Open Access

Protein kinase Cα stimulates hypoxia‑induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal‑regulated kinase 1/2 pathway

Rui Jiang, Yiwei Shi, Chao Zeng, Wenyan Yu, Aizhen Zhang, Yongcheng Du
Pages: 6814-6820
Published online on: 12 September 2017

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Ailanthone induces G2/M cell cycle arrest and apoptosis of SGC‑7901 human gastric cancer cells

Yuxin Chen, Ling Zhu, Xi Yang, Cheng Wei, Chuanrong Chen, Yang He, Zhaoning Ji
Pages: 6821-6827
Published online on: 13 September 2017

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Article Open Access

UPLC‑QTOFMS‑based metabolomic analysis of the serum of hypoxic preconditioning mice

Jie Liu, Gang Zhan, Dewei Chen, Jian Chen, Zhi‑Bin Yuan, Er‑Long Zhang, Yi‑Xing Gao, Gang Xu, Bing‑Da Sun, Wenting Liao, Yu‑Qi Gao
Pages: 6828-6836
Published online on: 13 September 2017

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Article Open Access

Isolated chromosome 8p23.2‑pter deletion: Novel evidence for developmental delay, intellectual disability, microcephaly and neurobehavioral disorders

Shanshan Shi, Shaobin Lin, Baojiang Chen, Yi Zhou
Pages: 6837-6845
Published online on: 07 September 2017

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Article

Application of next‑generation sequencing for molecular diagnosis in a large family with osteogenesis imperfecta type I

Mengxia Ni, Hao Ding, Shuaimei Liu, Peiran Zhu, Qiuyue Wu, Weiwei Li, Jing Zhang, Weijun Jiang, Xinyi Xia
Pages: 6846-6849
Published online on: 07 September 2017

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Article

Differential regulation by IFN‑γ on TNF‑α‑induced chemokine expression in synovial fibroblasts from temporomandibular joint

Kouji Ohta, Takako Naruse, Hiroki Kato, Yoko Ishida, Takayuki Nakagawa, Shigehiro Ono, Hideo Shigeishi, Masaaki Takechi
Pages: 6850-6857
Published online on: 07 September 2017

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Article

MicroRNA‑106b regulates skeletal muscle insulin sensitivity and glucose homeostasis by targeting mitofusion‑2

Ying Zhang, Wei He, Yuan‑Fu Gao, Zhong‑Min Fan, Chun‑Lin Gao, Zheng‑Kun Xia
Pages: 6858-6863
Published online on: 08 September 2017

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Article

Neuroprotective effects of curcumin alleviate lumbar intervertebral disc degeneration through regulating the expression of iNOS, COX‑2, TGF‑β1/2, MMP‑9 and BDNF in a rat model

Yuan Hu, Jin‑Shu Tang, Shu‑Xun Hou, Xiu‑Xiu Shi, Jiang Qin, Tie‑Song Zhang, Xiao‑Jing Wang
Pages: 6864-6869
Published online on: 12 September 2017

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Article

Exposure of keratinocytes to non‑thermal dielectric barrier discharge plasma increases the level of 8‑oxoguanine via inhibition of its repair enzyme

Ki Cheon Kim, Madduma Hewage Susara Ruwan Kumara, Kyoung Ah Kang, Mei Jing Piao, Min Chang Oh, Yea Seong Ryu, Jin Oh Jo, Young Sun Mok, Jennifer H. Shin, Yeunsoo Park, Seong Bong Kim, Suk Jae Yoo, Jin Won Hyun
Pages: 6870-6875
Published online on: 11 September 2017

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Article

Implementing targeted region capture sequencing for the clinical detection of Alagille syndrome: An efficient and cost‑effective method

Tianhong Huang, Guilin Yang, Xiao Dang, Feijian Ao, Jiankang Li, Yizhou He, Qiyuan Tang, Qing He
Pages: 6876-6881
Published online on: 07 September 2017

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Article

PHD3 affects gastric cancer progression by negatively regulating HIF1A

Ying‑Jie Xia, Xiao‑Ting Jiang, Shi‑Bin Jiang, Xu‑Jun He, Jun‑Gang Luo, Zheng‑Chuang Liu, Liang Wang, Hou‑Quan Tao, Jian‑Zhong Chen
Pages: 6882-6889
Published online on: 11 September 2017

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Article

Inhibitory effect of brassinin on TNF‑α‑induced vascular inflammation in human umbilical vein endothelial cells

Byung Hyuk Han, Jung Joo Yoon, Eun Sik Choi, Da Hye Jeong, Yun Jung Lee, Dae Gill Kang, Ho Sub Lee
Pages: 6890-6895
Published online on: 31 August 2017

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Article

CXC chemokine‑7 inhibits growth and migration of oral tongue squamous cell carcinoma cells, mediated by the epithelial‑mesenchymal transition signaling pathway

Tong‑Jun Liu, Jian‑Lian Guo, Xin Xu
Pages: 6896-6903
Published online on: 08 September 2017

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Article

Urotensin II enhances transforming growth factor‑β1 expression and secretion in the kidney during aristolochic acid nephropathy

Suxian Chen, Yadi Wang, Yizeng Wan
Pages: 6904-6909
Published online on: 05 September 2017

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Article

Depletion of ubiA prenyltransferase domain containing 1 expression promotes angiotensin II‑induced hypertrophic response in AC16 human myocardial cells via modulating the expression levels of coenzyme Q10 and endothelial nitric oxide synthase

Bingju Yan, Yingxian Sun, Jun Wang
Pages: 6910-6915
Published online on: 31 August 2017

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Article

Soluble interleukin‑2 receptor as a factor associated with angiogenesis in gastric cancer

Wen‑Feng Yan, Chang‑Fu Nie, Gang Wu, Jian‑Cheng Zhang, Yuan‑Zeng Zhu, Wei Zhang, Pei‑Chun Sun
Pages: 6916-6919
Published online on: 07 September 2017

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Article

MicroRNA‑214 targets Wnt3a to suppress liver cancer cell proliferation

Yang Yang, Zhenghao Zhao, Ni Hou, Yulong Li, Xiaofei Wang, Fei Wu, Ruifang Sun, Jia Han, Hongfei Sun, Tusheng Song, Chen Huang, Yuan Shao
Pages: 6920-6927
Published online on: 13 September 2017

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Article

Uric acid induces the expression of TNF‑α via the ROS‑MAPK‑NF‑κB signaling pathway in rat vascular smooth muscle cells

Lirong Tang, Yu'e Xu, Ying Wei, Xu He
Pages: 6928-6933
Published online on: 31 August 2017

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Article

Palmitate induces myocardial lipotoxic injury via the endoplasmic reticulum stress‑mediated apoptosis pathway

Lu Zou, Xiaoyan Li, Nan Wu, Pengyu Jia, Chunting Liu, Dalin Jia
Pages: 6934-6939
Published online on: 31 August 2017

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Article

MicroRNA‑146a promotes the proliferation of rat vascular smooth muscle cells by downregulating p53 signaling

Yu Luo, Wei Xiong, Shaohong Dong, Feng Liu, Huadong Liu, Jianghua Li
Pages: 6940-6945
Published online on: 12 September 2017

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Article

Overexpression of ATP5b promotes cell proliferation in asthma

Jianhong Zuo, Mingsheng Lei, Meilin Wen, Yikun Chen, Zhigang Liu
Pages: 6946-6952
Published online on: 31 August 2017

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Article

High CCL5 expression is associated with osteosarcoma metastasis and poor prognosis of patients with osteosarcoma

Kai Sun, Chen Gong, Hao Peng, Hongsong Fang, Jianlin Zhou, Jianping Li, Sen Chen, Huifeng Zheng
Pages: 6953-6957
Published online on: 11 September 2017

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Article

Role of ghrelin in small intestinal motility following pediatric intracerebral hemorrhage in mice

Jieyu Zan, Lei Song, Jiejie Wang, Rong Zou, Fei Hong, Jinhua Zhao, Yijun Cheng, Ming Xu
Pages: 6958-6966
Published online on: 12 September 2017

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Article

Role of matrix metalloproteinase‑7 and apoptosis‑associated gene expression levels in the pathogenesis of atrial fibrosis in a Beagle dog model

Min Jia, Zai‑Bo Li, Lin Li, Hong‑Tao Chu, Zhuang‑Zhuang Li
Pages: 6967-6973
Published online on: 31 August 2017

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Article

FK506 suppresses hypoxia‑induced inflammation and protects tight junction function via the CaN‑NFATc1 signaling pathway in retinal microvascular epithelial cells

Yaguang Hu, Boyu Yang, Yue Xu, Li Jiang, Ching-Kit Tsui, Xiaoling Liang
Pages: 6974-6980
Published online on: 12 September 2017

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Article

Protective role of berberine and Coptischinensis extract on T2MD rats and associated islet Rin‑5f cells

Yu‑Yu Jiang, Han‑Ming Cui, Jia‑Long Wang, Hui Liu, Meng‑Meng Dang, Qiu‑Yan Zhang, Fang Yang, Jian‑Tao Kou, Xiao‑Lin Tong
Pages: 6981-6991
Published online on: 12 September 2017

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Article

Sinulariolide suppresses LPS‑induced phenotypic and functional maturation of dendritic cells

Ting‑Wen Chung, Yi‑Rong Li, Wei Yuan Huang, Jui‑Hsin Su, Hong‑Lin Chan, Sheng‑Hao Lin, Chin‑San Liu, Shih‑Chao Lin, Chi‑Chien Lin, Ching‑Hsiung Lin
Pages: 6992-7000
Published online on: 13 September 2017

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Article

Autophagy and ER stress in LPS/GalN‑induced acute liver injury

Ting Shi, Weifang Song, Ruiling Xu
Pages: 7001-7005
Published online on: 31 August 2017

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Article

Moderate hypothermia induces protein SUMOylation in bone marrow stromal cells and enhances their tolerance to hypoxia

Wenbo Ren, Xiaofang Ma, Xiaozhi Liu, Yanxia Li, Zhongmin Jiang, Yujun Zhao, Chen Li, Xin Li
Pages: 7006-7012
Published online on: 05 September 2017

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Article

Ferruginol exhibits anticancer effects in OVCAR‑3 human ovary cancer cells by inducing apoptosis, inhibition of cancer cell migration and G2/M phase cell cycle arrest Retraction in /10.3892/mmr.2021.11868

Wen‑Dong Xiong, Jian Gong, Chao Xing
Pages: 7013-7017
Published online on: 13 September 2017

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Article

Endothelial progenitor cell‑derived extracellular vesicle‑meditated cell‑to‑cell communication regulates the proliferation and osteoblastic differentiation of bone mesenchymal stromal cells

Yunhao Qin, Changqing Zhang
Pages: 7018-7024
Published online on: 31 August 2017

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Article

Effects of coadministration of low dose cannabinoid type 2 receptor agonist and morphine on vanilloid receptor 1 expression in a rat model of cancer pain

Mingyue Zhang, Meng Chi, Huichao Zou, Songyu Tian, Zhaodi Zhang, Guonian Wang
Pages: 7025-7031
Published online on: 13 September 2017

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Article

A novel non‑contact communication between human keratinocytes and T cells: Exosomes derived from keratinocytes support superantigen‑induced proliferation of resting T cells

Xiao‑Wei Cai, Rong Zhu, Lei Ran, Yi‑Qian Li, Ke Huang, Jing Peng, Wei He, Chun‑Li Zhou, Ru‑Peng Wang
Pages: 7032-7038
Published online on: 13 September 2017

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Article

Long noncoding RNA‑p21 modulates cellular senescence via the Wnt/β‑catenin signaling pathway in mesenchymal stem cells

Wenzheng Xia, Lei Zhuang, Xia Deng, Meng Hou
Pages: 7039-7047
Published online on: 07 September 2017

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Article

MicroRNA‑373 promotes tumorigenesis of renal cell carcinoma in vitro and in vivo

Yanli Li, Da Zhang, Jiaxiang Wang
Pages: 7048-7055
Published online on: 08 September 2017

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Article

Detection of RACK1 and CTNNBL1‑induced activation of mouse splenocytes using an immunoprecipitation‑based technique

Bohan Dong, Guangli Dai, Lei Xu, Damin Shi
Pages: 7056-7063
Published online on: 13 September 2017

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Article

mTOR inhibition reduces growth and adhesion of hepatocellular carcinoma cells in vitro

Tobias Engl, Jochen Rutz, Sebastian Maxeiner, Eva Juengel, Frederik Roos, Wael Khoder, Wolf O. Bechstein, Karen Nelson, Igor Tsaur, Axel Haferkamp, Roman A. Blaheta
Pages: 7064-7071
Published online on: 31 August 2017

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Article

Identification of lncRNA EGOT as a tumor suppressor in renal cell carcinoma Corrigendum in /10.3892/mmr.2024.13194

Lu Jin, Jing Quan, Xiang Pan, Tao He, Jia Hu, Yifan Li, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yun Chen, Yongqing Lai
Pages: 7072-7079
Published online on: 12 September 2017

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Article

Effect of 1,25(OH)2D3 on high glucose‑induced autophagy inhibition in peritoneum

Lina Yang, Yi Fan, Xiuli Zhang, Jin Liu, Jianfei Ma
Pages: 7080-7085
Published online on: 31 August 2017

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Article

Transfection with Livin and Survivin shRNA inhibits the growth and proliferation of non‑small cell lung cancer cells

Qinmiao Huang, Yiming Zeng, Huihuang Lin, Huaping Zhang, Dongyong Yang
Pages: 7086-7091
Published online on: 13 September 2017

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Article

Glutathione system in Wolfram syndrome 1‑deficient mice

Rando Porosk, Kalle Kilk, Riina Mahlapuu, Anton Terasmaa, Ursel Soomets
Pages: 7092-7097
Published online on: 31 August 2017

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Article

SIRT1 confers protection against ischemia/reperfusion injury in cardiomyocytes via regulation of uncoupling protein 2 expression

Min Deng, Daxin Wang, Shenghu He, Rixin Xu, Yong Xie
Pages: 7098-7104
Published online on: 11 September 2017

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Article

A multi‑targeted tyrosine kinase inhibitor lenvatinib for the treatment of mice with advanced glioblastoma

Jia Li, Chang‑Lin Zou, Zhi‑Ming Zhang, Lian‑Jie Lv, Hai‑Bo Qiao, Xiu‑Ju Chen
Pages: 7105-7111
Published online on: 11 September 2017

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Article

Gambogic acid suppresses inflammation in rheumatoid arthritis rats via PI3K/Akt/mTOR signaling pathway

Xiaodan Wu, Li Long, Jian Liu, Jin Zhang, Tong Wu, Xixi Chen, Bing Zhou, Ting‑Zhuo Lv
Pages: 7112-7118
Published online on: 11 September 2017

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Article

Knockdown of Fstl1 attenuates hepatic stellate cell activation through the TGF‑β1/Smad3 signaling pathway

Hongye Shang, Xiangjin Liu, Hui Guo
Pages: 7119-7123
Published online on: 08 September 2017

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Article

microRNA‑188 acts as a tumour suppressor in glioma by directly targeting the IGF2BP2 gene Retraction in /10.3892/mmr.2022.12826

Li Ding, Ling Wang, Feng Guo
Pages: 7124-7130
Published online on: 07 September 2017

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Article

Aberrantly expressed transcription factors C/EBP and SOX4 have positive effects in the development of chronic myeloid leukemia

Fei Dong, Guili Zhang, Xia Zhang, Xuena Liu, Na Wang, Chengming Sun
Pages: 7131-7137
Published online on: 13 September 2017

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Article

GOLPH3 promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma via mTOR and Wnt/β‑catenin signal activation

Jian‑Hua Wang, Lin‑Jing Yuan, Rong‑Xin Liang, Zi‑Gang Liu, Bo‑Hai Li, Zhe‑Sheng Wen, Shu‑Ting Huang, Min Zheng
Pages: 7138-7144
Published online on: 13 September 2017

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Article

Association of SREBP2 gene polymorphisms with the risk of osteonecrosis of the femoral head relates to gene expression and lipid metabolism disorders

Yang Song, Zhenwu Du, Bingpeng Chen, Ming Ren, Qiwei Yang, Yujie Sui, Qingyu Wang, Ao Wang, Haiyue Zhao, Yanguo Qin, Guizhen Zhang
Pages: 7145-7153
Published online on: 12 September 2017

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Article

MicroRNA‑195 inhibits cell proliferation, migration and invasion in laryngeal squamous cell carcinoma by targeting ROCK1

Yang Liu, Jixiang Liu, Lin Wang, Xiangli Yang, Xiang Liu
Pages: 7154-7162
Published online on: 11 September 2017

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Article

Adiponectin receptor agonist AdipoRon suppresses adipogenesis in C3H10T1/2 cells through the adenosine monophosphate‑activated protein kinase signaling pathway

Shu‑Juan Wang, Wen‑Yi Lu, Kai‑Yan Liu
Pages: 7163-7169
Published online on: 08 September 2017

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Review Open Access

Thymic function in the regulation of T cells, and molecular mechanisms underlying the modulation of cytokines and stress signaling (Review)

Fenggen Yan, Xiumei Mo, Junfeng Liu, Siqi Ye, Xing Zeng, Dacan Chen
Pages: 7175-7184
Published online on: 19 September 2017

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Article Open Access

High expression of endoglin in primary breast cancer may predict response to neoadjuvant chemotherapy

Kun‑Ming Rau, Yu‑Li Su, Shan‑Hsuan Li, Meng‑Che Hsieh, Shis‑Chung Wu, Fong‑Fu Chou, Tai‑Jan Chiu, Yen‑Hao Chen, Chien‑Ting Liu
Pages: 7185-7190
Published online on: 20 September 2017

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Article Open Access

Immunoreactivities of calbindin‑D28k, calretinin and parvalbumin in the somatosensory cortex of rodents during normal aging

Ji Hyeon Ahn, Seongkweon Hong, Joon Ha Park, In Hye Kim, Jeong Hwi Cho, Tae‑Kyeong Lee, Jae‑Chul Lee, Bai Hui Chen, Bich‑Na Shin, Eun Joo Bae, Yong Hwan Jeon, Young‑Myeong Kim, Moo‑Ho Won, Soo Young Choi
Pages: 7191-7198
Published online on: 21 September 2017

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Article Open Access

Efficient inhibition of duck hepatitis B virus DNA by the CRISPR/Cas9 system

Qingfen Zheng, Li Bai, Sujun Zheng, Mei Liu, Jinyan Zhang, Ting Wang, Zhongwei Xu, Yu Chen, Jiansheng Li, Zhongping Duan
Pages: 7199-7204
Published online on: 19 September 2017

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Article Open Access

Shear stress induces human aortic endothelial cell apoptosis via interleukin‑1 receptor‑associated kinase 2‑induced endoplasmic reticulum stress

Longfei Pan, Zhou Hong, Lei Yu, Yanxia Gao, Rui Zhang, Hui Feng, Lijuan Su, Gang Wang
Pages: 7205-7212
Published online on: 19 September 2017

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Article Open Access

Beneficial effects of extracts from Lucilia sericata maggots on burn wounds in rats

Haixu Bian, Qiaoli Yang, Tao Ma, Wei Li, Jialin Duan, Guo Wei, Xiaoxiao Wu, Fei Mu, Rui Lin, Aidong Wen, Miaomiao Xi
Pages: 7213-7220
Published online on: 20 September 2017

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Article Open Access

Oncogenic miR‑132 sustains proliferation and self‑renewal potential by inhibition of polypyrimidine tract‑binding protein 2 in glioblastoma cells

Silong Lou, Jia Ji, Xin Cheng, Jian Ruan, Rong Li, Zhengjun Guo
Pages: 7221-7228
Published online on: 21 September 2017

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Article Open Access

DhHP‑6 attenuates cerebral ischemia‑reperfusion injury in rats through the inhibition of apoptosis

Yingshi Ji, Xin Yan, Yang Hu, Huan Xue, Jianfeng Sun, Huaqiu Chen, Jiayu Zhang, Liping Wang, Baigong Xue, Li Sun
Pages: 7229-7236
Published online on: 21 September 2017

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Article Open Access

Geniposide promotes autophagy to inhibit insulin resistance in HepG2 cells via P62/NF‑κB/GLUT‑4

Hongwei Jiang, Yujin Ma, Junqiang Yan, Jie Liu, Liping Li
Pages: 7237-7244
Published online on: 18 September 2017

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Article Open Access

MicroRNA‑509 acts as a tumor suppressor in tongue squamous cell carcinoma by targeting epidermal growth factor receptor Retraction in /10.3892/mmr.2024.13176

Chao Hou, Yan Dong, Fenghe Zhang, Bo Du
Pages: 7245-7252
Published online on: 20 September 2017

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Article Open Access

Nutrient deprivation induces apoptosis of nucleus pulposus cells via activation of the BNIP3/AIF signalling pathway

Jie Liu, Chao Yuan, Luqiao Pu, Jian Wang
Pages: 7253-7260
Published online on: 20 September 2017

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Article Open Access

MicroRNA‑138‑5p regulates neural stem cell proliferation and differentiation in vitro by targeting TRIP6 expression

Juan Wang, Jixia Li, Jian Yang, Lianguo Zhang, Shane Gao, Fei Jiao, Maoli Yi, Jun Xu
Pages: 7261-7266
Published online on: 18 September 2017

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Article Open Access

Effect of integrin‑linked kinase gene silencing on microRNA expression in ovarian cancer

Dandan Yuan, Yilei Zhao, Yang Wang, Jianhua Che, Wenhua Tan, Yuxia Jin, Fei Wang, Peiliang Li, Shuyan Fu, Qian Liu, Wenliang Zhu
Pages: 7267-7276
Published online on: 19 September 2017

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Article Open Access

CMIP is oncogenic in human gastric cancer cells

Jianlin Zhang, Jin Huang, Xingyu Wang, Weidong Chen, Qinqing Tang, Maoyong Fang, Yeben Qian
Pages: 7277-7286
Published online on: 20 September 2017

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Inhibition of microRNA‑155 ameliorates cardiac fibrosis in the process of angiotensin II‑induced cardiac remodeling

Yuzhen Wei, Xiaofei Yan, Lianhua Yan, Fen Hu, Wenhan Ma, Ya Wang, Shuai Lu, Qiutang Zeng, Zhaohui Wang
Pages: 7287-7296
Published online on: 21 September 2017

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Promoting potential of adipose derived stem cells on peripheral nerve regeneration

Jiayan Guo, Shu Guo, Yuxin Wang, Yanqiu Yu
Pages: 7297-7304
Published online on: 21 September 2017

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Article Open Access

Isoflurane exposure regulates the cell viability and BDNF expression of astrocytes via upregulation of TREK‑1

Cui‑Hong Zhou, Ya‑Hong Zhang, Fen Xue, Shan‑Shan Xue, Yun‑Chun Chen, Ting Gu, Zheng‑Wu Peng, Hua‑Ning Wang
Pages: 7305-7314
Published online on: 20 September 2017

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Protective effects of GV1001 on myocardial ischemia‑reperfusion injury

Ji‑Eun Chang, Hyun Jun Kim, Sanghoon Jheon, Cheong Lim
Pages: 7315-7320
Published online on: 19 September 2017

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Article Open Access

A novel FBN1 mutation causes autosomal dominant Marfan syndrome

Ying Xiao, Xiaoqi Liu, Xiaoxin Guo, Liping Liu, Linxin Jiang, Qi Wang, Bo Gong
Pages: 7321-7328
Published online on: 20 September 2017

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Article Open Access

MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer Retraction in /10.3892/mmr.2023.13130

Woda Shi, Jianxiang Song, Wencai Wang, Yajun Zhang, Shiying Zheng
Pages: 7329-7336
Published online on: 19 September 2017

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Article Open Access

Peptidome analysis of amniotic fluid from pregnancies with preeclampsia

Yating Qian, Lei Zhang, Can Rui, Hongjuan Ding, Pengyuan Mao, Hongjie Ruan, Ruizhe Jia
Pages: 7337-7344
Published online on: 21 September 2017

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Article Open Access

Comparison of morphology, phenotypes and function between cultured human IL‑4‑DC and IFN‑DC

Zhiliang Jin, Jing Fan, Yajuan Zhang, Yongxiang Yi, Lili Wang, Dandan Yin, Tao Deng, Wei Ye
Pages: 7345-7354
Published online on: 21 September 2017

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Glucosylceramide synthase regulates the proliferation and apoptosis of liver cells in vitro by Bcl‑2/Bax pathway

Jun‑Feng Li, Su‑Jun Zheng, Li‑Li Wang, Shuang Liu, Feng Ren, Yu Chen, Li Bai, Mei Liu, Zhong‑Ping Duan
Pages: 7355-7360
Published online on: 21 September 2017

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Article Open Access

Succinate promotes skeletal muscle protein synthesis via Erk1/2 signaling pathway Corrigendum in /10.3892/mmr.2024.13293

Yexian Yuan, Yaqiong Xu, Jingren Xu, Bingqing Liang, Xingcai Cai, Canjun Zhu, Lina Wang, Songbo Wang, Xiaotong Zhu, Ping Gao, Xiuqi Wang, Yongliang Zhang, Qingyan Jiang, Gang Shu
Pages: 7361-7366
Published online on: 20 September 2017

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Article Open Access

ING2, a tumor associated gene, enhances PAI‑1 and HSPA1A expression with HDAC1 and mSin3A through the PHD domain and C‑terminal

Chiyo Ohkouchi, Kensuke Kumamoto, Motonobu Saito, Teruhide Ishigame, Shin‑Ichi Suzuki, Seiichi Takenoshita, Cutis C. Harris
Pages: 7367-7374
Published online on: 20 September 2017

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Article Open Access

Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model Expression of Concern in /10.3892/mmr.2025.13691 Corrigendum in /10.3892/mmr.2025.13729

Zhong‑Hua Fu, Guang‑Hua Guo, Zhen‑Fang Xiong, Xincheng Liao, Ming‑Zhuo Liu, Jinhua Luo
Pages: 7375-7381
Published online on: 20 September 2017

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Microarray and bioinformatics analyses of gene expression profiles in BALB/c murine macrophage polarization

Li Jiang, Xueqin Li, Yingying Zhang, Mengying Zhang, Zongsheng Tang, Kun Lv
Pages: 7382-7390
Published online on: 19 September 2017

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Article Open Access

Triptolide inhibits proliferation, differentiation and induces apoptosis of osteoblastic MC3T3‑E1 cells

Wei Ji, Shijia Liu, Xia Zhao, Yunke Guo, Sha Xia, Yueyang Lu, Menyun Yin, Xiao Xu
Pages: 7391-7397
Published online on: 21 September 2017

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Icariin improves acute kidney injury and proteinuria in a rat model of pregnancy‑induced hypertension

Wenyu Zhang, Wei Yuan, Ning Xu, Jinping Li, Wenxiu Chang
Pages: 7398-7404
Published online on: 19 September 2017

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Application of the amniotic fluid metabolome to the study of fetal malformations, using Down syndrome as a specific model

Jun Huang, Jinhua Mo, Guili Zhao, Qiyin Lin, Guanhui Wei, Weinan Deng, Dunjin Chen, Bolan Yu
Pages: 7405-7415
Published online on: 18 September 2017

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Effect of modified Xiaochaihu decoction‑containing serum on HepG2.2.15 cells via the JAK2/STAT3 signaling pathway

Shaofang Chen, Zhanglin Wang, Shichuan Wan, Hai Huang, Huiqing Liang
Pages: 7416-7422
Published online on: 20 September 2017

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Article Open Access

Exploring the key genes and pathways of osteosarcoma with pulmonary metastasis using a gene expression microarray

Zhongju Shi, Hengxing Zhou, Bin Pan, Lu Lu, Zhijian Wei, Linlin Shi, Xue Yao, Yi Kang, Shiqing Feng
Pages: 7423-7431
Published online on: 21 September 2017

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Vitamin D alleviates lipopolysaccharide‑induced acute lung injury via regulation of the renin‑angiotensin system

Jun Xu, Jialai Yang, Jian Chen, Qingli Luo, Qiu Zhang, Hong Zhang
Pages: 7432-7438
Published online on: 20 September 2017

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Neuroprotective effect of total flavonoids from Ilex pubescens against focal cerebral ischemia/reperfusion injury in rats

Xiaoyan Fang, Yujie Li, Jingyi Qiao, Ying Guo, Mingsan Miao
Pages: 7439-7449
Published online on: 20 September 2017

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Gene expression analysis: Regulation of key genes associated with mycophenolate mofetil treatment of symptomatic carotid artery stenosis

Feng Jin, Kai Wang, Xiaochuan Sun, Zhanpu Zhang, Ping Han
Pages: 7450-7458
Published online on: 20 September 2017

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Transplantation of periodontal ligament cell sheets expressing human β‑defensin‑3 promotes anti‑inflammation in a canine model of periodontitis

Minwen Zhu, Bo Miao, Jianhua Zhu, Haiyan Wang, Zengtong Zhou
Pages: 7459-7467
Published online on: 19 September 2017

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Integrated mRNAseq and microRNAseq data analysis for grade III gliomas

Junqiang Dai, Zhitong Bing, Yinian Zhang, Qiao Li, Liang Niu, Wentao Liang, Guoqiang Yuan, Lei Duan, Hang Yin, Yawen Pan
Pages: 7468-7478
Published online on: 20 September 2017

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Integrated strategy of differentially expressed genes associated with ulcerative colitis

Juerong Feng, Qian Gao, Qing Liu, Fan Wang, Xue Lin, Qiu Zhao, Jing Liu, Jin Li
Pages: 7479-7489
Published online on: 18 September 2017

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Effect of antioxidant of bamboo leaves on gene expression associated with mouse embryonic fibroblast reproduction and embryonic development

Feng Yu, Xiaowei Qian, Zhanghui Zeng, Xiaoli Zhao, Rong Hou, Zhihe Zhang, Hongwu Bian, Ning Han, Junhui Wang, Muyuan Zhu
Pages: 7490-7496
Published online on: 18 September 2017

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Hypermethylation of WIF1 and its inhibitory role in the tumor growth of endometrial adenocarcinoma

Xinchao Deng, Congzhe Hou, Huali Wang, Tingting Liang, Lin Zhu
Pages: 7497-7503
Published online on: 20 September 2017

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Article Open Access

Role of PIM2 in allergic asthma

Wei Du, Tiantian Chen, Yingmeng Ni, Xiaoxia Hou, Youchao Yu, Qi Zhou, Fang Wu, Wei Tang, Guochao Shi
Pages: 7504-7512
Published online on: 18 September 2017

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Paeonol exerts potential activities to inhibit the growth, migration and invasion of human gastric cancer BGC823 cells via downregulating MMP‑2 and MMP‑9

Zhong‑Kuan Lyu, Chang‑Ling Li, Yan Jin, Yu‑Zhao Liu, Xi Zhang, Fang Zhang, Lu‑Ning Ning, Er‑Shun Liang, Min Ma, Wei Gao, Ming‑Xiang Zhang, De‑Shan Liu
Pages: 7513-7519
Published online on: 21 September 2017

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Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway

Qi Xiao, Qifa Ye, Wei Wang, Jiansheng Xiao, Biqi Fu, Zhiping Xia, Xingjian Zhang, Zhongzhong Liu, Xianpeng Zeng
Pages: 7520-7526
Published online on: 18 September 2017

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Screening of potential genes contributing to the macrocycle drug resistance of C. albicans via microarray analysis

Jing Yang, Wei Zhang, Jian Sun, Zhiqin Xi, Zusha Qiao, Jinyu Zhang, Yan Wang, Ying Ji, Wenli Feng
Pages: 7527-7533
Published online on: 20 September 2017

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Polyaniline promotes peripheral nerve regeneration by enhancement of the brain‑derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling pathway

Lin Fan, Yan Xiong, Zhen Fu, Dingfeng Xu, Lei Wang, Yong Chen, Haoyang Xia, Na Peng, Shaojun Ye, Yanfeng Wang, Lina Zhang, Qifa Ye
Pages: 7534-7540
Published online on: 20 September 2017

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Asymmetric dimethylarginine downregulates sarco/endoplasmic reticulum calcium‑ATPase 3 and induces endoplasmic reticulum stress in human umbilical vein endothelial cells

Weikang Guo, Zongli Diao, Wenhu Liu
Pages: 7541-7547
Published online on: 19 September 2017

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Coxsackieviruses B3 infection of myocardial microvascular endothelial cells activates fractalkine via the ERK1/2 signaling pathway

Jili Wen, Congxin Huang
Pages: 7548-7552
Published online on: 20 September 2017

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Article

microRNA‑96 regulates the proliferation of nucleus pulposus cells by targeting ARID2/AKT signaling

Bo Tao, Jiaoyu Yi, Changzhao Huang, Wang Xu, Chao Qin, Lei Chen, Jincai Chen, Yan Gao, Ruiying Wang
Pages: 7553-7560
Published online on: 20 September 2017

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Article

GPVI‑Fc‑PEG improves cerebral infarct volume and cerebral thrombosis in mouse model with cerebral thrombosis

Yimae Wufuer, Xuefeng Shan, Magaoweiya Sailike, Kamile Adilaimu, Songfeng Ma, Huguo Wang
Pages: 7561-7568
Published online on: 20 September 2017

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Article

Mitochondrial DNA‑induced inflammatory damage contributes to myocardial ischemia reperfusion injury in rats: Cardioprotective role of epigallocatechin

Chao‑Yi Qin, Hong‑Wei Zhang, Jun Gu, Fei Xu, Huai‑Min Liang, Kang‑Jun Fan, Jia‑Yu Shen, Zheng‑Hua Xiao, Er‑Yong Zhang, Jia Hu
Pages: 7569-7576
Published online on: 19 September 2017

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Article

Cerebral ischemia/reperfusion injury induces airway mucus hypersecretion in rats and activates IL‑13‑associated inflammatory mechanisms

Baoning Xu, Lei Zhang, Yuqin Che, Chengyang Song, Wenjun Jiang, Jianhua Fan, Dali Tian
Pages: 7577-7584
Published online on: 19 September 2017

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Kisspeptin inhibits cancer growth and metastasis via activation of EIF2AK2

Tae‑Hun Kim, Sung‑Gook Cho
Pages: 7585-7590
Published online on: 21 September 2017

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Low doses of Co nanoparticles induce death and regulate osteogenic differentiation in MG‑63 cells

Qinglin Han, Fan Liu
Pages: 7591-7596
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Folate‑targeted polymeric micelles loaded with superparamagnetic iron oxide as a contrast agent for magnetic resonance imaging of a human tongue cancer cell line

Min‑Yi Cui, Zhi Dong, Huasong Cai, Kun Huang, Yi Liu, Zhuangnian Fang, Xiangmin Li, Yanji Luo
Pages: 7597-7602
Published online on: 20 September 2017

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Protective and therapeutic effects of Danhong injection on acute pancreatitis‑associated lung injury

Qin Liu, Fuzhou Hua, Changqing Deng, Jing Zhang, Guohai Xu, Yanhui Hu
Pages: 7603-7608
Published online on: 19 September 2017

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NF‑κB‑miR15a‑bFGF/VEGFA axis contributes to the impaired angiogenic capacity of BM‑MSCs in high fat diet‑fed mice

Zhuoli Zhu, Xueqi Gan, Haiyang Yu
Pages: 7609-7616
Published online on: 18 September 2017

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Investigation of crucial genes and microRNAs in conventional osteosarcoma using gene expression profiling analysis

Chuangang Peng, Qi Yang, Bo Wei, Baoming Yuan, Yong Liu, Yuxiang Li, Dawer Gu, Guochao Yin, Bo Wang, Dehui Xu, Xuebing Zhang, Daliang Kong
Pages: 7617-7624
Published online on: 18 September 2017

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Use of immunoproteomics to identify immunogenic proteins in a rat model of acute respiratory distress syndrome

Zongshu Ji, Haiyan Liu, Linsen Fang, Youxin Yu, Zheng Zhou
Pages: 7625-7632
Published online on: 20 September 2017

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Smilax glabra Rhizoma affects the pharmacokinetics and tissue distribution of methotrexate by increasing the P‑glycoprotein mRNA expression in rats after oral administration

Yang Li, Shigui Deng, Ya Ζhao, Lijuan Liu, Ruizhi Zhao
Pages: 7633-7640
Published online on: 20 September 2017

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Article

Middle pregnancy ultrasound screening for fetal chromosomal diseases

Li Liu, Ping Zhou, Zemin Cao, Xiaojun Tan
Pages: 7641-7648
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MicroRNA‑340 inhibits tumor cell proliferation, migration and invasion, and induces apoptosis in hepatocellular carcinoma

Ziyao Wang, Dan Song, Ping Huang
Pages: 7649-7656
Published online on: 21 September 2017

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Celastrol alleviates angiotensin II‑mediated vascular smooth muscle cell senescence via induction of autophagy

Xian‑Jie Xu, Wei‑Bo Zhao, Shi‑Bin Feng, Cheng Sun, Qiang Chen, Bing Ni, Hou‑Yuan Hu
Pages: 7657-7664
Published online on: 20 September 2017

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RNA‑sequence analysis of samples from patients with idiopathic adhesive capsulitis

Jiaming Cui, Tongda Zhang, Jianyi Xiong, Wei Lu, Li Duan, Weimin Zhu, Daping Wang
Pages: 7665-7672
Published online on: 21 September 2017

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Effect of hippocampal L‑NBP on BDNF and TrkB expression and neurological function of vascular dementia rats

Yujing Huang, Zhaohui Li, Guangxian Nan
Pages: 7673-7678
Published online on: 20 September 2017

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Halofuginone attenuates articular cartilage degeneration by inhibition of elevated TGF‑β1 signaling in articular cartilage in a rodent osteoarthritis model

Wenbo Mu, Boyong Xu, Hairong Ma, Baochao Ji, Zhendong Zhang, Jiao Li, Abdusami Amat, Li Cao
Pages: 7679-7684
Published online on: 20 September 2017

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Efficient gene therapy with a combination of ultrasound‑targeted microbubble destruction and PEI/DNA/NLS complexes

Yi‑Jia Wang, Qing Zhou, Sheng Cao, Bo Hu, Qing Deng, Nan Jiang, Jingjing Cui
Pages: 7685-7691
Published online on: 18 September 2017

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Article

Mechanical stress affects the osteogenic differentiation of human ligamentum flavum cells via the BMP‑Smad1 signaling pathway

Yu Shunzhi, Li Zhonghai, Yan Ning
Pages: 7692-7698
Published online on: 20 September 2017

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Myricitrin decreases traumatic injury of the spinal cord and exhibits antioxidant and anti‑inflammatory activities in a rat model via inhibition of COX‑2, TGF‑β1, p53 and elevation of Bcl‑2/Bax signaling pathway

Yang Lei
Pages: 7699-7705
Published online on: 21 September 2017

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Article

Edoxaban improves venous thrombosis via increasing hydrogen sulfide and homocysteine in rat model

Wei Song, Hongbo Ci, Guanglei Tian, Yanjun Zhang, Xiaohu Ge
Pages: 7706-7714
Published online on: 21 September 2017

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Alteration of oxidative stress and inflammatory cytokines induces apoptosis in diabetic nephropathy

Jibin Sha, Bo Sui, Xiaoqing Su, Qingfang Meng, Chenggang Zhang
Pages: 7715-7723
Published online on: 19 September 2017

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Differentially expressed long non‑coding RNAs and mRNAs in patients with IgA nephropathy

Nan Zuo, Yun Li, Nan Liu, Lining Wang
Pages: 7724-7730
Published online on: 20 September 2017

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Article

Thioredoxin is implicated in the anti‑apoptotic effects of grape seed proanthocyanidin extract during hyperglycemia

Xiang Ren, Heyuan Lu, Nina Wang, Chenghong Zhang, Yunpeng Ji, Shiqi Cui, Yichen Dong, Kaiyuan Yang, Mengyi Du, Fengsheng Diao, Li Kong
Pages: 7731-7737
Published online on: 18 September 2017

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Systemic overexpression of the 11β‑HSD1 promotes endoplasmic reticulum stress in multiple tissues and the development of metabolic syndrome in mice

Chenxiao Li, Jihan Xia, Wenjuan Zhu, Leilei Xin, Cuiping An, Shulin Yang, Kui Li
Pages: 7738-7744
Published online on: 20 September 2017

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Antioxidant and anti‑inflammatory effects of DHK‑medicated serum on high glucose‑induced injury in endothelial cells

Ziyang Zhang, Wenpei Chen, Yandong Wang, Tianqin Xiong, Chenghao Zhou, Xiaolan Yao, Baoqin Lin
Pages: 7745-7751
Published online on: 21 September 2017

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Hedyotis diffusa Willd suppresses metastasis in 5‑fluorouracil‑resistant colorectal cancer cells by regulating the TGF‑β signaling pathway

Zijun Lai, Zhaokun Yan, Wujin Chen, Jun Peng, Jianyu Feng, Qiongyu Li, Yiyi Jin, Jiumao Lin
Pages: 7752-7758
Published online on: 18 September 2017

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Identification of 14‑3‑3ζ as a potential biomarker in gastric cancer by proteomics‑based analysis

Xin‑Xin Liu, Hua Ye, Peng Wang, Yi Zhang, Jian‑Ying Zhang
Pages: 7759-7765
Published online on: 18 September 2017

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Circulating miRNA‑21 is a promising biomarker for heart failure

Jianghua Zhang, Qiang Xing, Xianhui Zhou, Jinxin Li, Yaodong Li, Lin Zhang, Qina Zhou, Baopeng Tang
Pages: 7766-7774
Published online on: 21 September 2017

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Aberrant promoter methylation of multiple genes in VSMC proliferation induced by Hcy

Sheng‑Chao Ma, Jian‑Cheng Cao, Hui‑Ping Zhang, Yun Jiao, Hui Zhang, Yang‑Yang He, Yan‑Hua Wang, Xiao‑Ling Yang, An‑Ning Yang, Jue Tian, Ming‑Hao Zhang, Xiao‑Ming Yang, Guan‑Jun Lu, Shao‑Ju Jin, Yue‑Xia Jia, Yi‑Deng Jiang
Pages: 7775-7783
Published online on: 19 September 2017

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SPARCL1 suppresses cell migration and invasion in renal cell carcinoma

Hui Ye, Wei‑Gang Wang, Jun Cao, Xi‑Chun Hu
Pages: 7784-7790
Published online on: 20 September 2017

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Correlation analysis between liver metastasis and serum levels of miR‑200 and miR‑141 in patients with colorectal cancer

Meng Ding, Tao Zhang, Shijie Li, Ying Zhang, Yunfeng Qiu, Bin Zhang
Pages: 7791-7795
Published online on: 20 September 2017

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Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway

Hai Lan, Hongyin Yuan, Congyao Lin
Pages: 7796-7804
Published online on: 20 September 2017

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Gallic acid inhibits the growth of calf pulmonary arterial endothelial cells through cell death and glutathione depletion

Woo Hyun Park
Pages: 7805-7812
Published online on: 21 September 2017

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Article

MicroRNA‑198 contributes to lupus nephritis progression by inhibition of phosphatase and tensin homology deleted on chromosome ten expression

Danyu Cui, Dingji Zhu, Hao Ren, Jingli Lin, Weinan Lai, Qin Huang, Jinjun Zhao, Min Yang
Pages: 7813-7820
Published online on: 19 September 2017

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MicroRNA‑186 targets IGF‑1R and exerts tumor‑suppressing functions in glioma Retraction in /10.3892/mmr.2022.12778

Jian Jiang, Weijie Wang, Dazhao Fang, Xiaodong Jin, Lianshu Ding, Xiaoyang Sun
Pages: 7821-7828
Published online on: 21 September 2017

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Panax Notoginseng Saponins attenuates sevoflurane‑induced nerve cell injury by modulating AKT signaling pathway

Xu Yang, Sun Yang, Chen Hong, Wang Yu, Wang Guonian
Pages: 7829-7834
Published online on: 19 September 2017

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Xanomeline derivative EUK1001 attenuates Alzheimer's disease pathology in a triple transgenic mouse model

Ziyan Li, Kaili Jia, Yale Duan, Dong Wang, Zongli Zhou, Suzhen Dong
Pages: 7835-7840
Published online on: 18 September 2017

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H2O2 induces caveolin‑1 degradation and impaired mitochondrial function in E11 podocytes

Ya‑Hui Chen, Wei‑Wen Lin, Chin‑San Liu, Shih‑Li Su
Pages: 7841-7847
Published online on: 18 September 2017

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Decreased expression of hsa‑miR‑372 predicts poor prognosis in patients with gallbladder cancer by affecting chloride intracellular channel 1

Ning Zhou, Wei Cheng, Chuang Peng, Yi Liu, Bo Jiang
Pages: 7848-7854
Published online on: 19 September 2017

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Pigment epithelium‑derived factor protects human glomerular mesangial cells from diabetes via NOXO1‑iNOS suppression

Ling Gao, Yingjie Hu, Jing Li
Pages: 7855-7863
Published online on: 20 September 2017

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MicroRNA‑212 inhibits colorectal cancer cell viability and invasion by directly targeting PIK3R3 Retraction in /10.3892/mmr.2023.13025

Jian Zhang, Yongkang Zhang, Xiaoyun Li, Hongbo Wang, Quan Li, Xiaofeng Liao
Pages: 7864-7872
Published online on: 20 September 2017

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[Retracted] Cathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway

Aiguo Liu, Xuan Gao, Qingbin Zhang, Lianqun Cui
Pages: 7873-7873
Published online on: 20 September 2017

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January-2026 Volume 33 Issue 1

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Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
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Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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