|
1
|
Löscher W and Schmidt D: New horizons in
the development of antiepileptic drugs: The search for new targets.
Epilepsy Res. 60:77–159. 2004.PubMed/NCBI
|
|
2
|
Ravizza T, Gagliardi B, Noé F, Boer K,
Aronica E and Vezzani A: Innate and adaptive immunity during
epileptogenesis and spontaneous seizures: Evidence from
experimental models and human temporal lobe epilepsy. Neurobiol
Dis. 29:142–160. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Khurgel M and Ivy GO: Astrocytes in
kindling: Relevance to epileptogenesis. Epilepsy Res. 26:163–175.
1996. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Balasingam V, Tejada-Berges T, Wright E,
Bouckova R and Yong VW: Reactive astrogliosis in the neonatal mouse
brain and its modulation by cytokines. J Neurosci. 14:846–856.
1994.PubMed/NCBI
|
|
5
|
Mattson MP and Camandola S: NF-kappaB in
neuronal plasticity and neurodegenerative disorders. J Clin Invest.
107:247–254. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
De Simoni MG, Perego C, Ravizza T, Moneta
D, Conti M, Marchesi F, De Luigi A, Garattini S and Vezzani A:
Inflammatory cytokines and related genes are induced in the rat
hippocampus by limbic status epilepticus. Eur J Neurosci.
12:2623–2633. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Chen F, Castranova V and Shi X: New
insights into the role of nuclear factor-kappaB in cell growth
regulation. Am J Pathol. 159:387–397. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Jobin C and Sartor RB: The I kappa
B/NF-kappa B system: A key determinant of mucosalinflammation and
protection. Am J Physiol Cell Physiol. 278:C451–C462.
2000.PubMed/NCBI
|
|
9
|
Sisodiya SM, Lin WR, Harding BN, Squier MV
and Thom M: Drug resistance in epilepsy: Expression of drug
resistance proteins in common causes of refractory epilepsy. Brain.
125:22–31. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Cole SP, Bhardwaj G, Gerlach JH, Mackie
JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AM and
Deeley RG: Overexpression of a transporter gene in a
multidrug-resistant human lung cancer cell line. Science.
258:1650–1654. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Juliano RL and Ling V: A surface
glycoprotein modulating drug permeability in Chinese hamster ovary
cell mutants. Biochim Biophys Acta. 455:152–162. 1976. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Callaghan R, Crowley E, Potter S and Kerr
ID: P-glycoprotein: So many ways to turn it on. J Clin Pharmacol.
48:365–378. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Golden PL and Pardridge WM: P-Glycoprotein
on astrocyte foot processes of unfixed isolated human brain
capillaries. Brain Res. 819:143–146. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Declèves X, Regina A, Laplanche JL, Roux
F, Boval B, Launay JM and Scherrmann JM: Functional expression of
P-glycoprotein and multidrug resistance-associated protein (Mrp1)
in primary cultures of rat astrocytes. J Neurosci Res. 60:594–601.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Pardridge WM, Golden PL, Kang YS and
Bickel U: Brain microvascular and astrocyte localization of
P-glycoprotein. J Neurochem. 68:1278–1285. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mercier C, Declèves X, Masseguin C,
Fragner P, Tardy M, Roux F, Gabrion J and Scherrmann JM:
P-glycoprotein (ABCB1) but not multidrug resistance-associated
protein 1 (ABCC1) is induced by doxorubicin in primary cultures of
rat astrocytes. J Neurochem. 87:820–830. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Regina A, Koman A, Piciotti M, El Hafny B,
Center MS, Bergmann R, Couraud PO and Roux F: Mrp1 multidrug
resistance-associated protein and P-glycoprotein expression in rat
brain microvessel endothelial cells. J Neurochem. 71:705–715. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hirrlinger J, König J and Dringen R:
Expression of mRNAs of multidrug resistance proteins (Mrps) in
cultured rat astrocytes, oligodendrocytes, microglial cells and
neurones. J Neurochem. 82:716–719. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Brandt C, Bethmann K, Gastens AM and
Löscher W: The multidrug transporter hypothesis of drug resistance
in epilepsy: Proof-of-principle in a rat model of temporal lobe
epilepsy. Neurobiol Dis. 24:202–211. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wetherington J, Serrano G and Dingledine
R: Astrocytes in the epileptic brain. Neuron. 58:168–178. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Marchi N, Hallene KL, Kight KM, Cucullo L,
Moddel G, Bingaman W, Dini G, Vezzani A and Janigro D: Significance
of MDR1 and multiple drug resistance in refractory human epileptic
brain. BMC Med. 2:372004. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Gaillard PJ, van der Sandt IC, Voorwinden
LH, Vu D, Nielsen JL, de Boer AG and Breimer DD: Astrocytes
increase the functional expression of P-glycoprotein in an in vitro
model of the blood-brain barrier. Pharm Res. 17:1198–1205. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
de Bock F, Dornand J and Rondouin G:
Release of TNF alpha in the rat hippocampus following epileptic
seizures and excitotoxic neuronal damage. Neuroreport. 7:1125–1129.
1996. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Rizzi M, Perego C, Aliprandi M, Richichi
C, Ravizza T, Colella D, Velískŏvá J, Moshé SL, De Simoni MG and
Vezzani A: Glia activation and cytokine increase in rat hippocampus
by kainic acid-induced status epilepticus during postnatal
development. Neurobiol Dis. 14:494–503. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Vezzani A, Moneta D, Richichi C, Aliprandi
M, Burrows SJ, Ravizza T, Perego C and De Simoni MG: Functional
role of inflammatory cytokines and antiinflammatory molecules in
seizures and epileptogenesis. Epilepsia. 43 Suppl 5:S30–S35. 2002.
View Article : Google Scholar
|
|
26
|
Bharti AC and Aggarwal BB: Nuclear
factor-kappa B and cancer: Its role in prevention and therapy.
Biochem Pharmacol. 64:883–888. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Sarkar D, Lebedeva IV, Emdad L, Kang DC,
Baldwin AS Jr and Fisher PB: Human polynucleotide phosphorylase
(hPNPaseold-35): A potential link between aging and inflammation.
Cancer Res. 64:7473–7478. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Spiegl-Kreinecker S, Buchroithner J,
Elbling L, Steiner E, Wurm G, Bodenteich A, Fischer J, Micksche M
and Berger W: Expression and functional activity of the
ABC-transporter proteins P-glycoprotein and multidrug-resistance
protein 1 in human brain tumor cells and astrocytes. J Neurooncol.
57:27–36. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Travis J: Glia: The brain's other cells.
Science. 266:970–972. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Dvoriantchikova G and Ivanov D: Tumor
necrosis factor-alpha mediates activation of NF-κB and JNK
signaling cascades in retinal ganglion cells and astrocytes in
opposite ways. Eur J Neurosci. 40:3171–3178. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Cui M, Huang Y, Tian C, Zhao Y and Zheng
J: FOXO3a inhibits TNF-α- and IL-1β-induced astrocyte
proliferation: Implication for reactive astrogliosis. Glia.
59:641–654. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Faijerson J, Tinsley RB, Apricó K,
Thorsell A, Nodin C, Nilsson M, Blomstrand F and Eriksson PS:
Reactive astrogliosis induces astrocytic differentiation of adult
neural stem/progenitor cells in vitro. J Neurosci Res.
84:1415–1424. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Golden PL and Pardridge WM: Brain
microvascular P-glycoprotein and a revised model of multidrug
resistance in brain. Cell Mol Neurobiol. 20:165–181. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Allan SM and Rothwell NJ: Cytokines and
acute neurodegeneration. Nat Rev Neurosci. 2:734–744. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Abbott NJ, Khan EU, Rollinson CM, Reichel
A, Janigro D, Dombrowski SM, Dobbie MS and Begley DJ: Drug
resistance in epilepsy: The role of the blood-brain barrier.
Novartis Found Symp. 243(38–53): 180–185. 2002.
|
|
36
|
Löscher W and Potschka H: Role of
multidrug transporters in pharmacoresistance to antiepileptic
drugs. J Pharmacol Exp Ther. 301:7–14. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Fernandes A, Barateiro A, Falcão AS, Silva
SL, Vaz AR, Brito MA, Silva RF and Brites D: Astrocyte reactivity
to unconjugated bilirubin requires TNF-α and IL-1β receptor
signaling pathways. Glia. 59:14–25. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Thévenod F, Friedmann JM, Katsen AD and
Hauser IA: Up-regulation of multidrug resistance P-glycoprotein via
nuclear factor-kappaB activation protects kidney proximal tubule
cells from cadmium- and reactive oxygen species-induced apoptosis.
J Biol Chem. 275:1887–1896. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Johnstone RW, Cretney E and Smyth MJ:
P-glycoprotein protects leukemia cells against caspase-dependent,
but not caspase-independent, cell death. Blood. 93:1075–1085.
1999.PubMed/NCBI
|
