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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2018 Volume 17 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Biological functions and role of CCN1/Cyr61 in embryogenesis and tumorigenesis in the female reproductive system (Review)

Rui Yang, Ying Chen, Daozhen Chen
Pages: 3-10
Published online on: 26 October 2017

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Article Open Access

Mycoleptodonoides aitchisonii suppresses asthma via Th2 and Th1 cell regulation in an ovalbumin‑induced asthma mouse model

Soon‑Young Lee, Chun‑Sik Bae, Ji‑Hye Seo, Seung Sik Cho, Min‑Suk Bae, Deuk‑Sil Oh, Dae‑Hun Park
Pages: 11-20
Published online on: 26 October 2017

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Article Open Access

Limb remote ischemic post‑conditioning reduces injury and improves long‑term behavioral recovery in rats following subarachnoid hemorrhage: Possible involvement of the autophagic process Retraction in /10.3892/mmr.2024.13419

Xiang Hu, Tao Lv, Shao‑Feng Yang, Xiao‑Hua Zhang, Yi‑Feng Miao
Pages: 21-30
Published online on: 24 October 2017

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Article Open Access

Vitamin E (α‑tocopherol) ameliorates aristolochic acid‑induced renal tubular epithelial cell death by attenuating oxidative stress and caspase‑3 activation

Tsai‑Kun Wu, Ying‑Ru Pan, Hsueh‑Fang Wang, Chyou‑Wei Wei, Yung‑Luen Yu
Pages: 31-36
Published online on: 27 October 2017

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Article Open Access

Genetic characteristics of polycistronic system‑mediated randomly‑inserted multi‑transgenes in miniature pigs and mice

Siyuan Kong, Li Li, Wenjuan Zhu, Leilei Xin, Jinxue Ruan, Yubo Zhang, Shulin Yang, Kui Li
Pages: 37-50
Published online on: 20 October 2017

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Article Open Access

Salidroside could enhance the cytotoxic effect of L‑OHP on colorectal cancer cells

Xiaoming Shi, Wei Zhao, Yongbin Yang, Shengchun Wu, Bonan Lv
Pages: 51-58
Published online on: 20 October 2017

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Article Open Access

Messenger RNA sequencing reveals similar mechanisms between neonatal and acute respiratory distress syndrome

Hua Mei, Yuheng Zhang, Chunzhi Liu, Yayu Zhang, Chunli Liu, Dan Song, Chun Xin, Jing Wang, Jonathan Josephs‑Spaulding, Yan Zhu, Feng Tang
Pages: 59-70
Published online on: 26 October 2017

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Article Open Access

Human umbilical cord mesenchymal stem cells alleviate interstitial fibrosis and cardiac dysfunction in a dilated cardiomyopathy rat model by inhibiting TNF‑α and TGF‑β1/ERK1/2 signaling pathways

Changyi Zhang, Guichi Zhou, Yezeng Chen, Sizheng Liu, Fen Chen, Lichun Xie, Wei Wang, Yonggang Zhang, Tianyou Wang, Xiulan Lai, Lian Ma
Pages: 71-78
Published online on: 26 October 2017

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Article Open Access

Antiangiogenic effects of recombinant human endostatin in lung cancers

Lang He, Chaofen Zhao, Yunxiang Li, Guocheng Du, Kang Liu, Dandan Cui, Lina Tang, Xun Wu, Shimin Wen, Hong Chen
Pages: 79-86
Published online on: 24 October 2017

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Article Open Access

Cornin protects SH‑SY5Y cells against oxygen and glucose deprivation‑induced autophagy through the PI3K/Akt/mTOR pathway

Changling Ding, Jie Zhang, Baoyuan Li, Zhaoxing Ding, Wenna Cheng, Fei Gao, Ye Zhang, Yangyang Xu, Shuping Zhang
Pages: 87-92
Published online on: 25 October 2017

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Article Open Access

Quantitative proteomic study of the plasma reveals acute phase response and LXR/RXR and FXR/RXR activation in the chronic unpredictable mild stress mouse model of depression

Chuangchuang Yang, Chanjuan Zhou, Jie Li, Zhi Chen, Haiyang Shi, Wensong Yang, Yinhua Qin, Lin Lü, Libo Zhao, Liang Fang, Haiyang Wang, Zicheng Hu, Peng Xie
Pages: 93-102
Published online on: 20 October 2017

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Article Open Access

Curcumin alleviates liver oxidative stress in type 1 diabetic rats

Zhenglu Xie, Binbin Wu, Guozhi Shen, Xiaqing Li, Qianying Wu
Pages: 103-108
Published online on: 26 October 2017

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Article Open Access

Identification of biomarkers for childhood obesity based on expressional correlation and functional similarity

Zheng‑Lun Zhu, Qiu‑Meng Yang, Chen Li, Jun Chen, Min Xiang, Ming‑Min Chen, Min Yan, Zheng‑Gang Zhu
Pages: 109-116
Published online on: 27 October 2017

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Article Open Access

DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53‑deficient pancreatic cancer cells

Wei Jing, Na Song, Yunpeng Liu, Xiujuan Qu, Kezuo Hou, Xianghong Yang, Xiaofang Che
Pages: 117-124
Published online on: 27 October 2017

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Article Open Access

XIAP underlies apoptosis resistance of renal cell carcinoma cells

Wen Zheng Yang, Haijiang Zhou, Yong Yan
Pages: 125-130
Published online on: 27 October 2017

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Article Open Access

Overexpression of miR‑185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson's disease

Zhi Wen, Jie Zhang, Peng Tang, Ning Tu, Ke Wang, Guangyao Wu
Pages: 131-137
Published online on: 26 October 2017

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Article Open Access

Preparation and characterization of acellular adipose tissue matrix using a combination of physical and chemical treatments

Mei Song, Yi Liu, Ling Hui
Pages: 138-146
Published online on: 24 October 2017

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Article Open Access

Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Pages: 147-157
Published online on: 26 October 2017

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Article Open Access

Effect of β‑ecdysterone on glucocorticoid‑induced apoptosis and autophagy in osteoblasts

Yang‑Hua Tang, Zhen‑Shuang Yue, Guo‑Song Li, Lin‑Ru Zeng, Da‑Wei Xin, Zhong‑Qing Hu, Can‑Da Xu
Pages: 158-164
Published online on: 20 October 2017

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Article Open Access

Gene expression profiles and protein‑protein interaction networks during tongue carcinogenesis in the tumor microenvironment

Wei Sun, Zeting Qiu, Wenqi Huang, Minghui Cao
Pages: 165-171
Published online on: 20 October 2017

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Article Open Access

Prenatal diagnosis and genetic counseling for Waardenburg syndrome type I and II in Chinese families

Li Wang, Litao Qin, Tao Li, Hongjian Liu, Lingcao Ma, Wan Li, Dong Wu, Hongdan Wang, Qiannan Guo, Liangjie Guo, Shixiu Liao
Pages: 172-178
Published online on: 25 October 2017

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Article Open Access

n-butanol extract from Folium isatidis inhibits the lipopolysaccharide-induced downregulation of CXCR1 and CXCR2 on human neutrophils

Beibei Wu, Liyin Wang, Lili Jiang, Lili Dong, Fengli Xu, Yili Lu, Jiahui Jin, Zhanyue Wang, Guang Liang, Xiaoou Shan
Pages: 179-185
Published online on: 25 October 2017

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Article Open Access

Predicting pathogenic genes for primary myelofibrosis based on a system‑network approach

Shu‑Cai Xu, Peng Ning
Pages: 186-192
Published online on: 20 October 2017

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Article Open Access

Abnormal DNA methylation may contribute to the progression of osteosarcoma

Xiao‑Gang Chen, Liang Ma, Jia‑Xin Xu
Pages: 193-199
Published online on: 25 October 2017

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Article Open Access

Wnt/β‑catenin pathway activation and silencing of the APC gene in HPV‑positive human cervical cancer‑derived cells

Erick Ayala‑Calvillo, Luis Humberto Mojica‑Vázquez, Alejandro García‑Carrancá, Leticia González‑Maya
Pages: 200-208
Published online on: 20 October 2017

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Article Open Access

Adiponectin and its receptors are involved in hypertensive vascular injury

Ruimin Guo, Min Han, Juan Song, Jun Liu, Yanni Sun
Pages: 209-215
Published online on: 25 October 2017

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Article Open Access

Construction of a prognostic prediction system for pancreatic ductal adenocarcinoma to investigate the key prognostic genes

Bingli Zheng, Jie Peng, Ablikim Mollayup, Ahmat Bakri, Lei Guo, Jianjiang Zheng, Hui Xu
Pages: 216-224
Published online on: 20 October 2017

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Article Open Access

Genetic variations in Bestrophin‑1 and associated clinical findings in two Chinese patients with juvenile‑onset and adult‑onset best vitelliform macular dystrophy

Ying Lin, Tao Li, Chenghong Ma, Hongbin Gao, Chuan Chen, Yi Zhu, Bingqian Liu, Yu Lian, Ying Huang, Haichun Li, Qingxiu Wu, Xiaoling Liang, Chenjin Jin, Xinhua Huang, Jianhua Ye, Lin Lu
Pages: 225-233
Published online on: 27 October 2017

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Article Open Access

Activation of corticotropin-releasing factor receptor 1 aggravates dextran sodium sulphate-induced colitis in mice by promoting M1 macrophage polarization

Hong Chen, Haitao Shi, Yaping Liu, Xiaoyang Ren, Shuixiang He, Xinming Chang, Yan Yin
Pages: 234-242
Published online on: 26 October 2017

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Article Open Access

TALENs-mediated homozygous CCR5Δ32 mutations endow CD4+ U87 cells with resistance against HIV‑1 infection

Ai Qing Yu, Yan Ding, Zhi Yong Lu, Yan Zhe Hao, Zhi Ping Teng, Shi Rong Yan, Dong Sheng Li, Yi Zeng
Pages: 243-249
Published online on: 26 October 2017

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Article Open Access

Three-dimensional hydrogel is suitable for targeted investigation of amoeboid migration of glioma cells

Yubao Huang, Luqing Tong, Li Yi, Chen Zhang, Long Hai, Tao Li, Shengping Yu, Wei Wang, Zhennan Tao, Haiwen Ma, Peidong Liu, Yang Xie, Xuejun Yang
Pages: 250-256
Published online on: 26 October 2017

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Article Open Access

Salidroside slows the progression of EA.hy926 cell senescence by regulating the cell cycle in an atherosclerosis model

Lin Sun, Fangfang Dou, Jiulin Chen, Huiying Chi, Sanli Xing, Te Liu, Shenwei Sun, Chuan Chen
Pages: 257-263
Published online on: 25 October 2017

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Article Open Access

Erythropoietin signaling increases neurogenesis and oligodendrogenesis of endogenous neural stem cells following spinal cord injury both in vivo and in vitro

Hui Zhang, Xiao Fang, Dake Huang, Qingli Luo, Meijuan Zheng, Kangkang Wang, Le Cao, Zongsheng Yin
Pages: 264-272
Published online on: 25 October 2017

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Article Open Access

Transcriptome sequencing revealed candidate genes relevant to mesenchymal stem cells' role in aortic dissection patients

Junlin Yang, Sili Zou, Mingfang Liao, Lefeng Qu
Pages: 273-283
Published online on: 20 October 2017

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Article Open Access

Aconitine induces apoptosis in H9c2 cardiac cells via mitochondria‑mediated pathway

Xiangting Gao, Xincai Zhang, Jun Hu, Xuehua Xu, Yuanyi Zuo, Yun Wang, Jingfeng Ding, Hongfei Xu, Shaohua Zhu
Pages: 284-292
Published online on: 26 October 2017

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Article Open Access

Effects of long‑term scopolamine treatment on cognitive deficits and calcium binding proteins immunoreactivities in the mouse hippocampus

Ji Hyeon Ahn, Bai Hui Chen, Bing Chun Yan, Joon Ha Park, Il Jun Kang, Tae‑Kyeong Lee, Jeong Hwi Cho, Bich‑Na Shin, Jae‑Chul Lee, Yong Hwan Jeon, Seongkweon Hong, Young Joo Lee, Soo Young Choi, Moo‑Ho Won
Pages: 293-299
Published online on: 27 October 2017

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Article

Genetically engineered recombinant adenovirus expressing interleukin‑2 for hepatocellular carcinoma therapy

Yunpeng Sun, Huanhuan Wu, Gang Chen, Xiaming Huang, Yunfeng Shan, Hongqi Shi, Qiyu Zhang, Yihu Zheng
Pages: 300-306
Published online on: 27 October 2017

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Article

Multi‑target inhibition by four tandem shRNAs embedded in homo‑ or hetero‑miRNA backbones

Xiao Du, Yanhui Cai, Wenjin Xi, Rui Zhang, Lintao Jia, Angang Yang, Jing Zhao, Bo Yan
Pages: 307-314
Published online on: 20 October 2017

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Article

Recombinant truncated TGF‑β receptor II attenuates carbon tetrachloride‑induced epithelial‑mesenchymal transition and liver fibrosis in rats

Luxin Li, Hongzhi Li, Zhen Zhang, Junya Zheng, Yongping Shi, Jieting Liu, Yanan Cao, Xiaohuan Yuan, Yanhui Chu
Pages: 315-321
Published online on: 20 October 2017

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Article

Role of the microRNA 181 family in glioma development

Liu Yang, Yueyun Ma, Yijuan Xin, Ruobin Han, Rui Li , Xiaoke Hao
Pages: 322-329
Published online on: 26 October 2017

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Article

Overexpression of miR‑21 promotes neural stem cell proliferation and neural differentiation via the Wnt/β‑catenin signaling pathway in vitro

Wei‑Min Zhang, Zhi‑Ren Zhang, Xi‑Tao Yang, Yong‑Gang Zhang, Yan‑Sheng Gao
Pages: 330-335
Published online on: 24 October 2017

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Article

The HMGB1‑IL‑17A axis contributes to hypoxia/reoxygenation injury via regulation of cardiomyocyte apoptosis and autophagy

Xiaorong Hu, Kai Zhang, Zhiqiang Chen, Hong Jiang, Weipan Xu
Pages: 336-341
Published online on: 20 October 2017

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Article

SIRT5 promotes cell proliferation and invasion in hepatocellular carcinoma by targeting E2F1

Liang Chang, Liang Xi, Yubin Liu, Rui Liu, Zhongshi Wu, Zhixiang Jian
Pages: 342-349
Published online on: 25 October 2017

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Article

Studying hepcidin and related pathways in osteoblasts using a mouse model with insulin receptor substrate 1‑loss of function

Jia Liu, Ling Qian, Linna Guo, Yunzhi Feng
Pages: 350-357
Published online on: 25 October 2017

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Article

Hedyotis diffusa Willd inhibits proliferation and induces apoptosis of 5‑FU resistant colorectal cancer cells by regulating the PI3K/AKT signaling pathway

Qiongyu Li, Zijun Lai, Zhaokun Yan, Jun Peng, Yiyi Jin, Lihui Wei, Jiumao Lin
Pages: 358-365
Published online on: 26 October 2017

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Article

Torin2 enhances the radiosensitivity of MCF‑7 breast cancer cells by downregulating the mTOR signaling pathway and ATM phosphorylation

Jia Luo, Guocheng Pi, He Xiao, Yunfei Ye, Qing Li, Lianhua Zhao, Huan Huang, Hong Luo, Qin Zhang, Dong Wang, Ge Wang
Pages: 366-373
Published online on: 20 October 2017

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Article

Melatonin ameliorates myocardial apoptosis by suppressing endoplasmic reticulum stress in rats with long‑term diabetic cardiomyopathy

Fang‑Yuan Xiong, Song‑Tao Tang, Huan Su, Hai‑Qin Tang, Pin Jiang, Qing Zhou, Yuan Wang, Hua‑Qing Zhu
Pages: 374-381
Published online on: 20 October 2017

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Case Report

Genetic diagnosis and pathogenic analysis of an atypical hereditary spherocytosis combined with UGT1A1 partial deficiency: A case report

Yan Yi, Xiqiang Dang, Yonggui Li, Chenyu Zhao, Haiyan Tang, Xiaoliu Shi
Pages: 382-387
Published online on: 25 October 2017

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Article

The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening

Han‑Tian Fan, Jun‑Fang Guo, Yu‑Xin Zhang, Yu‑Xi Gu, Zhong‑Qi Ning, Yan‑Jiang Qiao, Xing Wang
Pages: 388-393
Published online on: 25 October 2017

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Article

Expression, purification and epitope analysis of Pla a 2 allergen from Platanus acerifolia pollen

De‑Wang Wang, Wei‑Wei Ni, Yan‑Jun Zhou, Wen Huang, Meng‑Da Cao, Ling Meng, Ji‑Fu Wei
Pages: 394-399
Published online on: 26 October 2017

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Article

Coenzyme Q10 promotes osteoblast proliferation and differentiation and protects against ovariectomy-induced osteoporosis

Delu Zheng, Chenli Cui, Meng Yu, Xiang Li, Lu Wang, Xinyan Chen, Yichen Lin
Pages: 400-407
Published online on: 26 October 2017

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Article

Evaluation of the accuracy and sensitivity of high‑throughput sequencing technology using known microbiota

Fanjing Meng, Tingtao Chen, Xin Wang, Xiaolei Wang, Hua Wei, Puyuan Tian, Huan Wang, Xiaoxiao Zhao, Liang Shen, Hongbo Xin
Pages: 408-413
Published online on: 20 October 2017

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Article

Effects of hypoxia‑inducible factor‑1α on endometrial receptivity of women with polycystic ovary syndrome

Dongmei Zhao, Qinglan Qu, Huangguan Dai, Yueyang Liu, Lei Jiang, Xin Huang, Cuifang Hao
Pages: 414-421
Published online on: 26 October 2017

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Article

Effects of Dermatopontin gene silencing on apoptosis and proliferation of osteosarcoma MG‑63 cells

Li‑Cheng Xi, Yun‑Xi Ji, Dong Yin, Zi‑Xing Zhao, Si‑Cheng Huang, Shao‑Lin Yu, Bo‑Yu Liu, Hong‑Yu Li
Pages: 422-427
Published online on: 25 October 2017

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Article

Adiponectin promotes preadipocyte differentiation via the PPARγ pathway

Wenkai Yang, Chunli Yang, Jun Luo, Yutao Wei, Wenying Wang, Yingmei Zhong
Pages: 428-435
Published online on: 26 October 2017

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Article

Preparation of chitosan‑silicon dioxide/BCSG1‑siRNA nanoparticles to enhance therapeutic efficacy in breast cancer cells

Lan Cui, Ruifeng Zheng, Wentao Liu, Peihong Shen, Youcai Tang, Junbo Luo, Wei Zhang, Guocong Jia, Yongfeng Wang, Shuaihua Zhao, Qiaoting Xie, Yanwei Li
Pages: 436-441
Published online on: 26 October 2017

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Article

miR‑126 is essential for endothelial phenotype expression during endothelial differentiation in adipose‑derived stem cells

Han Xie, Fang Wang, Xiao Chen, Hao Ying
Pages: 442-446
Published online on: 27 October 2017

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Article

Apelin‑13 promotes cell proliferation in the H9c2 cardiomyoblast cell line by triggering extracellular signal‑regulated kinase 1/2 and protein kinase B phosphorylation

Luhua Yin, Pu Zhang, Chao Li, Jiafeng Si, Yongmei Wang, Xuemei Zhang, Deqing Zhang, Huanyi Zhang, Cong Lin
Pages: 447-451
Published online on: 27 October 2017

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Article

In vivo monitoring of magnetically labeled mesenchymal stem cells homing to rabbit hepatic VX2 tumors using magnetic resonance imaging

Yong Qin, Lisha Zhuo, Jinhua Cai, Xiaoya He, Bo Liu, Chuan Feng, Lin Zhang
Pages: 452-458
Published online on: 26 October 2017

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Article

Rottlerin inhibits cell growth, induces apoptosis and cell cycle arrest, and inhibits cell invasion in human hepatocellular carcinoma

Jichan Shi, Hongye Ning, Guiqing He, Yitong Huang, Zhengxing Wu, Lingling Jin, Xiangao Jiang
Pages: 459-464
Published online on: 27 October 2017

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Article Open Access

Overexpression of CCDC34 in colorectal cancer and its involvement in tumor growth, apoptosis and invasion

Wei Geng, Wei Liang, Yanan Fan, Zhibin Ye, Lixiao Zhang
Pages: 465-473
Published online on: 24 October 2017

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Article

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Aspirin ameliorates cerebral infarction through regulation of TLR4/NF‑κB‑mediated endoplasmic reticulum stress in mouse model

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Isolariciresinol-9'-O-α-L-arabinofuranoside protects against hydrogen peroxide‑induced apoptosis of human umbilical vein endothelial cells via a PI3K/Akt/Bad‑dependent pathway

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Protective effect of diltiazem on myocardial ischemic rats induced by isoproterenol

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UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway

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MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

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Minghui Jia, Xiaoyun Chen, Jili Liu, Jun Chen
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Zhihong Liu, Haiying Yu, Qiuye Guo
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miR-17-3P regulates the proliferation and survival of colon cancer cells by targeting Par4

Debao Lu, Liang Tang, Yan Zhuang, Peng Zhao
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Ryong Kong, Ok‑Hwa Kang, Yun‑Soo Seo, Tian Zhou, Sang‑A Kim, Dong‑Won Shin, Dong‑Yeul Kwon
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Presence of the minor allele of microRNA205 rs3842530 polymorphism increases 18FDG uptake in patients with breast cancer via targeting VEGF

Shiying Qu, Tie Wang, Jingwei Huang
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Astragaloside IV attenuates penicillin-induced epilepsy via inhibiting activation of the MAPK signaling pathway

Xingming Zhu, Yang Chen, Yuping Du, Qi Wan, Yan Xu, Jiayu Wu
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Isorhamnetin prevents H2O2‑induced oxidative stress in human retinal pigment epithelial cells

Jing Wang, Hui‑Min Gong, Hui‑Hui Zou, Ling Liang, Xin‑Yi Wu
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Application of oligonucleotides to construct a conditional targeting vector for porcine IκBα

Hegang Li, Xiaona Song, Feng Yang, Hanxun Bao, Xiaolong Lu, Flor M. Perez‑Campo, Jinshan Zhao
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Dioscin inhibits ischemic stroke‑induced inflammation through inhibition of the TLR4/MyD88/NF‑κB signaling pathway in a rat model

Shilin Zhu, Siyuan Tang, Feng Su
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Galangin increases ERK1/2 phosphorylation to decrease ADAM9 expression and prevents invasion in A172 glioma cells

Deqiang Lei, Fangcheng Zhang, Dongxiao Yao, Nanxiang Xiong, Xiaobing Jiang, Hongyang Zhao
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Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway

Huixiang Li, Qian Zhang, Xin Jin, Xiaowen Zou, Yuexuan Wang, Dexiang Hao, Fenghua Fu, Weihua Jiao, Cuixia Zhang, Houwen Lin, Keiichi Matsuzaki, Feng Zhao
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Clinical application of a novel diagnostic scheme including pancreatic β‑cell dysfunction for traumatic multiple organ dysfunction syndrome

Zhan‑Ke Wang, Rong‑Jian Chen, Shi‑Liang Wang, Guang‑Wei Li, Zhong‑Zhen Zhu, Qiang Huang, Zi‑Li Chen, Fan‑Chang Chen, Lei Deng, Xiao‑Peng Lan, Tian Hu
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Two‑component histidine kinase DRK1 is required for pathogenesis in Sporothrix schenckii

Zhenying Zhang, Binbin Hou, Yong Zhuo Wu, Ying Wang, Xiaoming Liu, Shixin Han
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Guangyu Wang, Yaguang Bi, Xiangdong Liu, Meng Wei, Qingyong Zhang
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Shuying Li, Zhanjun Liu, Ji Li, Aihua Liu, Lihua Zhu, Kui Yu, Ke Zhang
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Jin Yang, Liu‑Lin Xiong, You‑Cui Wang, Xiang He, Ling Jiang, Song‑Jun Fu, Xue‑Fei Han, Jia Liu, Ting‑Hua Wang
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Jin Ke, Weiwei Shao, Yasu Jiang, Junfei Xu, Feng Li, Jun Qin
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Zaiheng Zhang, Anmin Jin, Denglu Yan
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Neng‑Jiang Zhao, Ming‑Juan Liao, Jing‑Jing Wu, Ke‑Xin Chu
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A novel method to isolate mesenchymal stem cells from mouse umbilical cord

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Application of F0F1‑ATPase immuno‑biosensors for detecting Escherichia coli O157:H7

Ling Wei, Bao‑Ming Li, Cheng‑Bin Wang, Zi‑Jia Kang, Jie Sun, Hui‑Juan Wu, Yong‑Zhi Lun
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Trichosanthes kirilowii extract enhances repair of UVB radiation‑induced DNA damage by regulating BMAL1 and miR‑142‑3p in human keratinocytes

Ji‑Hye Joo, In‑Kee Hong, Nam Kyoung Kim, Eunmi Choi
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Effects of daphnetin combined with Bcl2‑siRNA on antiapoptotic genes in synovial fibroblasts of rats with collagen‑induced arthritis

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Liang Wei, Qi Wang, Yanfei Zhang, Cheng Yang, Hongxin Guan, Yiming Chen, Zhiyang Sun
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Quan Gong, Chao Liu, Cunde Wang, Li Zhuang, Lijuan Zhang, Xicai Wang
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Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression

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Different inhibitory effects on the proliferation and apoptosis of human and laboratory Borna disease virus‑infected human neuroblastoma SH‑SY5Y cells in vitro

Hua Huang, Hong Zhang, Dan Li, Shigang Chen, Chanjuan Zhou, Qi Li, Peng He, Liang Fang, Yong Zhang, Xiaomei Li, Jingjing Zhou, Lin Sun, Siwen Liu, Yujie Guo, Ying Huang, Peng Xie
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Ye Chen, Yue‑Yue Ding, Yan Ren, Lei Cao, Qiu‑Qin Xu, Ling Sun, Ming‑Guo Xu, Hai‑Tao Lv
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Liang Liang, Dan‑Ming Wei, Jian‑Jun Li, Dian‑Zhong Luo, Gang Chen, Yi‑Wu Dang, Xiao‑Yong Cai
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TIPE2 governs macrophage polarization via negative regulation of mTORC1

Yuan Jiang, Qiang Li, Yuanyuan Zhang, Yuzhi Gao, Libing Jiang, Zhimin Chen
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Endothelial‑to‑mesenchymal transition in human idiopathic dilated cardiomyopathy

Yeqing Xie, Jianquan Liao, Yong Yu, Qi Guo, Yingzhen Yang, Junbo Ge, Haozhu Chen, Ruizhen Chen
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Polygonum multiflorm alleviates glucocorticoid‑induced osteoporosis and Wnt signaling pathway

Manru Zhou, Jingkai Wu, Yongjie Yu, Yajun Yang, Jin Li, Liao Cui, Weimin Yao, Yuyu Liu
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Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats

Jian‑Liang Qiao, Juan Sun, Jun Li, Jun‑Jing Zhang, Xing‑Kai Meng
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Comparison of the osteogenic differentiation of orofacial bone marrow stromal cells prior to and following marsupialization in patients with odontogenic cyst

Yao Sun, Juan Zhang, Naiying Qian, Guoqi Sima, Jianming Zhang, Jiayong Zhong, Zhiqin Guo, Yawen Chen, Weijie Dong
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ORMDL3 may participate in the pathogenesis of bronchial epithelial‑mesenchymal transition in asthmatic mice with airway remodeling

Qi Cheng, Yunxiao Shang
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Alanine scanning mutagenesis of SP70 epitope in characterizing species‑specific antibodies induced by enterovirus 71‑based antigens

Meng Gao, Feng Zhang, Yun Zhu, Limei Gao, Yunshui Jiang, Yongneng Luo, Fangchang Zhuang, Zian Mao, Jiangsen Mao
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The shortening telomere length of T lymphocytes maybe associated with hyper‑function in servere aplastic anemia

Chaomeng Wang, Tian Zhang, Yihao Wang, Yang Li, Chunyan Liu, Hui Liu, Lijuan Li, Kai Ding, Ting Wang, Honglei Wang, Zonghong Shao, Rong Fu
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Elemene inhibits osteosarcoma growth by suppressing the renin‑angiotensin system signaling pathway

Lixiang Ding, Genai Zhang, Yu Hou, Jiao Chen, Yukun Yin
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HGF induces the serine‑phosphorylation and cell surface translocation of ROMK (Kir 1.1) channels in rat kidney cells

Takashi Kato, Kiyomasa Oka, Toshikazu Nakamura
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Tian‑Hang Li, Hong‑Xia Yan
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miR-92a regulates the expression levels of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 3 via sirtuin 1 signaling in hydrogen peroxide-induced vascular smooth muscle cells

Peng Liu, Jianfang Su, Xixi Song, Shixiao Wang
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HuR induces inflammatory responses in HUVECs and murine sepsis via binding to HMGB1

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Yu Wang, Yang Hu, Zhaoping Zeng, Yinghua Li, Huipeng Su, Yiwei Li, Ruiping Wang, Mingqian Zhang, Yongli Yang, Jie Deng
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Shuping You, Yun Guan, Weihong Li
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Oxymatrine induces A549 human non‑small lung cancer cell apoptosis via extrinsic and intrinsic pathways

Guang‑Zhou Zhou, Yan‑Yan Shi, Liu‑Su Cui, A‑Fang Li, Qing‑Qing Wang, Min Liu
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Bryostatin 1 causes attenuation of TPA‑mediated tumor promotion in mouse skin

Ning Zeng, Yi Xu, Yiping Wu, Tang Hongbo, Min Wu
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Repeated inhalation of sevoflurane inhibits the information transmission of Purkinje cells and delays motor development via the GABAA receptor ε subunit in neonatal mice

Hong Fang, Ze‑Hua Wang, Ying‑Jiang Bu, Zhi‑Jun Yuan, Guo‑Qiang Wang, Yan Guo, Xiao‑Yun Cheng, Wen‑Jie Qiu
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PirB inhibits axonal outgrowth via the PI3K/Akt/mTOR signaling pathway

Yong‑Yan Bi, Yong Quan
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Bing Xiao, Jian‑Gang Wang, Fang Han, Yu‑Xiu Shi
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LncRNA PVT1 regulate expression of HIF1α via functioning as ceRNA for miR‑199a‑5p in non‑small cell lung cancer under hypoxia

Chunhong Wang, Chunfang Han, Yibo Zhang, Fengqin Liu
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Downregulation of NKD1 in human osteosarcoma and its clinical significance

Xiang Chen, Ping Xu, Jianwei Zhu, Fan Liu
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Lipoic acid alleviates L‑DOPA‑induced dyskinesia in 6‑OHDA parkinsonian rats via anti‑oxidative stress

Su‑Fang Zhang, Cheng‑Long Xie, Jing‑Ya Lin, Mei‑Hua Wang, Xi‑Jin Wang, Zhen‑Guo Liu
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Isopsoralen regulates PPAR‑γ/WNT to inhibit oxidative stress in osteoporosis

Jian Wang, Gang Wang, Li Gong, Guanwen Sun, Bin Shi, Huhe Bao, Yan Duan
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Article

Jujuboside A attenuates norepinephrine-induced apoptosis of H9c2 cardiomyocytes by modulating MAPK and AKT signaling pathways

Chang‑Rong Wan, Dan‑Dan Han, Jian‑Qin Xu, Peng Yin, Xiao‑Long Xu, Chen Mei, Feng‑Hua Liu, Zhao‑Fei Xia
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Article

Pentoxifylline exerts anti-inflammatory effects on cerebral ischemia reperfusion‑induced injury in a rat model via the p38 mitogen-activated protein kinase signaling pathway

Jianqing Dong, Xinmei Yuan, Weiwei Xie
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High expression of long non‑coding HOTAIR correlated with hepatocarcinogenesis and metastasis

Da‑Ni Zhong, Yi‑Huan Luo, Wei‑Jia Mo, Xin Zhang, Zhong Tan, Na Zhao, Si‑Min Pang, Gang Chen, Min‑Hua Rong, Wei Tang
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Article

Traumatic stress affects alcohol‑drinking behavior through cocaine‑ and amphetamine‑regulated transcript 55‑102 in the paraventricular nucleus in rats

Jie Liu, Xue‑Ming Hu, Xiao‑Jian Li, Hui Zhao
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Angiotensin II induces monocyte chemoattractant protein‑1 expression by increasing reactive oxygen species‑mediated activation of the nuclear factor‑κB signaling pathway in osteoblasts

Changyao Wang, Cailong Zhang, Feng Zhou, Lei Gao, Yingzhen Wang, Chunsheng Wang, Yongtao Zhang
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Article

Effect of willed movement training on neurorehabilitation after focal cerebral ischemia and on the neural plasticity-associated signaling pathway

Zhi‑Wen Zhou, Qi‑Dong Yang, Qing‑Ping Tang, Jie Yang, Rong‑Jing Guo, Wen Jiang
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Article

Neuroprotective effect of polysaccharides from Gastrodia elata blume against corticosterone‑induced apoptosis in PC12 cells via inhibition of the endoplasmic reticulum stress‑mediated pathway

Benhong Zhou, Jun Tan, Chan Zhang, Yue Wu
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LncRNA PlncRNA‑1 regulates proliferation and differentiation of hair follicle stem cells through TGF‑β1‑mediated Wnt/β‑catenin signal pathway

Yuan Si, Jingzhu Bai, Jiang Wu, Qun Li, You Mo, Ruihua Fang, Wei Lai
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Recombinant TsP53 modulates intestinal epithelial barrier integrity via upregulation of ZO‑1 in LPS‑induced septic mice

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High‑cholesterol diet results in elevated amyloid‑β and oxysterols in rats

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Sparstolonin B selectively suppresses toll‑like receptor‑2 and ‑4 to alleviate neuropathic pain

Guanghui Jin, Xing Jin, Shuang Zhou
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Preventive effect of hesperidin modulates inflammatory responses and antioxidant status following acute myocardial infarction through the expression of PPAR‑γ and Bcl‑2 in model mice

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Anti-inflammatory activity of resveratrol prevents inflammation by inhibiting NF‑κB in animal models of acute pharyngitis

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microRNA‑211 suppresses the growth and metastasis of cervical cancer by directly targeting ZEB1

Guangyuan Chen, Ping Huang, Jiabin Xie, Rihong Li
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Protective effects of probucol on Ox-LDL-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via LOX‑1/ROS/MAPK signaling

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microRNA-222 promotes tumor growth and confers radioresistance in nasopharyngeal carcinoma by targeting PTEN

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Tao Fan, Guozhi Huang, Wen Wu, Rong Guo, Qing Zeng
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Decreased expression of interleukin‑37 and its anti‑inflammatory effect in allergic rhinitis

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Sparstolonin B prevents lumbar intervertebral disc degeneration through toll like receptor 4, NADPH oxidase activation and the protein kinase B signaling pathway

Jianhua Ge, Long Chen, Yunkang Yang, Xiaobo Lu, Zhou Xiang
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Lin Li, Jianhua Hao, Xian Jiang, Ping Li, Hu Sen
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MicroRNA‑212 inhibits the proliferation and invasion of human renal cell carcinoma by targeting FOXA1

Zhigang Tong, Xianfeng Meng, Jinsong Wang, Lixin Wang
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Dimethylation of Histone 3 Lysine 9 is sensitive to the epileptic activity, and affects the transcriptional regulation of the potassium channel Kcnj10 gene in epileptic rats

Shao‑Ping Zhang, Man Zhang, Hong Tao, Yan Luo, Tao He, Chun‑Hui Wang, Xiao‑Cheng Li, Ling Chen, Lin‑Na Zhang, Tao Sun, Qi‑Kuan Hu
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Downregulation of microRNA‑155 by preoperative administration of valproic acid prevents postoperative seizures by upregulating SCN1A

Zhijie Zhang, Zhenzhong Wang, Bo Zhang, Yan Liu
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MiR-4505 aggravates lipopolysaccharide-induced vascular endothelial injury by targeting heat shock protein A12B

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Liping Jiang, Zhen Tang
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Xiaoqiang Yang
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Xiaozhong Zhu, Zhiyuan Wang, Yanxun Zhao, Chao Jiang
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Feng Zhang, Chun‑Mei Zhang, Shu Li, Kun‑Kun Wang, Bin‑Bin Guo, Yao Fu, Lu‑Yang Liu, Yu Zhang, Hai‑Yu Jiang, Chang‑Jun Wu
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Yuefeng Li, Yunxia Wu, Zhigang Sun, Ruiyu Wang, Deliang Ma
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H89 dihydrochloride hydrate and calphostin C lower the body temperature through TRPV1

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17β-estradiol attenuates ovariectomy‑induced bone deterioration through the suppression of the ephA2/ephrinA2 signaling pathway

Lianyong Liu, Lin Zhou, Xiaorong Yang, Qi Liu, Ling Yang, Chao Zheng, Yongling Zhao, Zhenlin Zhang, Xiaohong Luo
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Mechanism of Astragalus polysaccharides in attenuating insulin resistance in Rats with type 2 diabetes mellitus via the regulation of liver microRNA‑203a‑3p

Zitai Wei, Siying Weng, Lei Wang, Zhujun Mao
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Yongsheng Ma, Hao Yang, Junqing Huang
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Quanhu Ge, Hongwei Zhang, Jixue Hou, Longfei Wan, Wenzhe Cheng, Xiaoyi Wang, Dan Dong, Congzhe Chen, Jie Xia, Jun Guo, Xueling Chen, Xiangwei Wu
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Paeoniflorin blocks the proliferation of vascular smooth muscle cells induced by platelet‑derived growth factor‑BB through ROS mediated ERK1/2 and p38 signaling pathways

Xianwei Fan, Jintao Wu, Haitao Yang, Lijie Yan, Shanling Wang
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Local honokiol application inhibits intimal thickening in rabbits following carotid artery balloon injury

Yu Wang, Danyang Zhao, Jing Sheng, Ping Lu
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SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
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Francesca Pirini, Sebastian Rodriguez‑Torres, Bola Grace Ayandibu, María Orera‑Clemente, Alberto Gonzalez‑de la Vega, Fahcina Lawson, Roland J. Thorpe, David Sidransky, Rafael Guerrero‑Preston
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Hua Wang, Zhong Chen, Yu Li, Qiaoyun Ji
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Dejun Li, Hongsheng Ji, Bao Zhao, Chunyang Xu, Wenjun Xia, Lihui Han, Dongqing Yu, Yuanrong Ju, Changjun Jin
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Yujie Wei, Bin Lai, Huiliang Liu, Yi Li, Wang Zhen, Ling Fu
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Di Liu, Lin Liu, Lizheng Wang, Sizhu Duan, Yanan Song, Meng Qu, Nan Gao, Jiaxin Wu, Haihong Zhang, Hui Wu, Wei Kong, Bin Yu, Xianghui Yu
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Yian Huang, Xu Liu, Guoxiang Wang, Yun Wang
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Matrine suppresses cardiac fibrosis by inhibiting the TGF‑β/Smad pathway in experimental diabetic cardiomyopathy

Yong Zhang, Lei Cui, Gongchang Guan, Junkui Wang, Chuan Qiu, Tielin Yang, Yan Guo, Zhongwei Liu
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Grape seed proanthocyanidin extract attenuates varicocele‑induced testicular oxidative injury in rats by activating the Nrf2‑antioxidant system

Yong Wang, Fan Chen, Ming Liang, Shouzhen Chen, Yaofeng Zhu, Zhichuan Zou, Benkang Shi
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Xi Wang, Yujie Ning, Bing Zhou, Lei Yang, Yingting Wang, Xiong Guo
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Yong‑Yan Cai, Chen Li, Zhi‑Xin Yan, Na Ma, Fang‑Fang Li
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Tingting Sun, Lin Tang, Miaomiao Zhang
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Ningjuan Ouyang, Peng Zhang, Runqing Fu, Guofang Shen, Lingyong Jiang, Bing Fang
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Lili Ding, Binfeng Zhang, Jinmei Li, Li Yang, Zhengtao Wang
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Zenghuang Ma, Xiaojie Xue
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Simvastatin ameliorates cognitive impairments via inhibition of oxidative stress‑induced apoptosis of hippocampal cells through the ERK/AKT signaling pathway in a rat model of senile dementia

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Reduced miRNA‑214 expression in oral mucosa contributes to the pathogenesis of oral lichen planus by targeting CD44

Haiyan Zheng, Shaohui Li
Pages: 1919-1925
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miR‑218 inhibits the proliferation of human glioma cells through downregulation of Yin Yang 1

Yong Gao, Laisheng Sun, Zicheng Wu, Chengmin Xuan, Junxia Zhang, Yongping You, Xincheng Chen
Pages: 1926-1932
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Effect of moesin phosphorylation on high‑dose sphingosine‑1‑phosphate‑induced endothelial responses

Yan Xiao, Jie Wu, Yongjun Yuan, Xiaohua Guo, Bo Chen, Qiaobing Huang
Pages: 1933-1939
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Long noncoding RNA‑ATB promotes cell proliferation, migration and invasion in gastric cancer

Ying Chen, Guoqing Wei, Hongwei Xia, Qiulin Tang, Feng Bi
Pages: 1940-1946
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The long noncoding RNA cancer susceptibility candidate 2 inhibits tumor progression in osteosarcoma

Lingyun Lu, Zhehao Dai, Qing Luo, Guohua Lv
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An RNA‑sequencing study identifies candidate genes for angiotensin II‑induced cardiac remodeling

Jin Shu, Zhanwen Liu, Li Jin, Haiya Wang
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Curcumin improves diabetes mellitus‑associated cerebral infarction by increasing the expression of GLUT1 and GLUT3

Mingyu Xia, Zankai Ye, Yanfeng Shi, Libo Zhou, Yang Hua
Pages: 1963-1969
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iASPP, a microRNA‑124 target, is aberrantly expressed in astrocytoma and regulates malignant glioma cell migration and viability

Xiangrong Liu, Jun Kang, Si Sun, Yumin Luo, Xunming Ji, Xianwei Zeng, Shangfeng Zhao
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The regulatory role of Fos related antigen‑1 in inflammatory bowel disease

Xianren Wang, Renle Guo, Yanfeng Lv, Rongzhan Fu
Pages: 1979-1985
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Huiling Wang, Yingliang Ou, Jinrui Ou, Zhixiang Jian
Pages: 1986-1992
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Cytochrome c is important in apoptosis of labial glands in primary Sjogren's syndrome

Yuanyuan Kang, Yan Sun, Ying Zhang, Zhe Wang
Pages: 1993-1997
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TWEAK/Fn14 promotes oxidative stress through AMPK/PGC‑1α/MnSOD signaling pathway in endothelial cells

Hengdao Liu, Hui Peng, Hong Xiang, Lingli Guo, Ruifang Chen, Shaoli Zhao, Wei Chen, Pan Chen, Hongwei Lu, Shuhua Chen
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microRNA‑625 targets Yes‑associated protein 1 to suppress cell proliferation and invasion of osteosarcoma

Zheng Luo, Gang Wu, Daiyang Zhang, Jun Liu, Renguo Ran
Pages: 2005-2011
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Neuroprotective effect of tanshinone IIA weakens spastic cerebral palsy through inflammation, p38MAPK and VEGF in neonatal rats

Wen‑Luo Zhang, Yue‑An Cao, Jing Xia, Li Tian, Lu Yang, Chao‑Sheng Peng
Pages: 2012-2018
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Curcumin reverses tobacco smoke‑induced epithelial‑mesenchymal transition by suppressing the MAPK pathway in the lungs of mice

Zhaofeng Liang, Rui Wu, Wei Xie, Mingming Zhu, Chunfeng Xie, Xiaoting Li, Jianyun Zhu, Weiwei Zhu, Jieshu Wu, Shanshan Geng, Wenrong Xu, Caiyun Zhong, Hongyu Han
Pages: 2019-2025
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Gambogic acid inhibits spinal cord injury and inflammation through suppressing the p38 and Akt signaling pathways

Qiao Fu, Chaojian Li, Lehua Yu
Pages: 2026-2032
Published online on: 10 November 2017

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The role of dual‑specificity phosphatase 1 and protein phosphatase 1 in β2‑adrenergic receptor‑mediated inhibition of extracellular signal regulated kinase 1/2 in triple negative breast cancer cell lines

Matilda Merve Tuglu, Saber Yari Bostanabad, Gozde Ozyon, Başak Dalkiliç, Hakan Gurdal
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Cellular properties of the fermented microalgae Pavlova lutheri and its isolated active peptide in osteoblastic differentiation of MG‑63 cells

Zhong‑Ji Qian, Bomi Ryu, Kyong‑Hwa Kang, Soo‑Jin Heo, Do‑Hyung Kang, Sung Yong Bae, Sun‑Joo Park, Jae‑Il Kim, Young‑Mog Kim, Yong‑Tae Kim, Won‑Kyo Jung
Pages: 2044-2050
Published online on: 15 November 2017

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miR‑660‑5p is associated with cell migration, invasion, proliferation and apoptosis in renal cell carcinoma Retraction in /10.3892/mmr.2024.13210

Tao He, Peijie Chen, Lu Jin, Jia Hu, Yifan Li, Liang Zhou, Shangqi Yang, Xiangming Mao, Yaoting Gui, Yun Chen, Yongqing Lai
Pages: 2051-2060
Published online on: 14 November 2017

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Mechanism of free radical generation in platelets and primary hepatocytes: A novel electron spin resonance study

Chiun‑Lang Wang, Po‑Sheng Yang, Jeng‑Ting Tsao, Thanasekaran Jayakumar, Meng‑Jiy Wang, Joen‑Rong Sheu, Duen‑Suey Chou
Pages: 2061-2069
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SRPK1‑siRNA suppresses K562 cell growth and induces apoptosis via the PARP‑caspase3 pathway

Hailian Wang, Wei Ge, Wen Jiang, Dong Li, Xiuli Ju
Pages: 2070-2076
Published online on: 13 November 2017

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

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Article Number: 50
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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Article Number: 39
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Diabetic keratopathy and nuclear proteins (Review)

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Article Number: 35
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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
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Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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