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Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25

  • Authors:
    • Yuan Zhang
    • Ying Wang
    • Xiao‑Hui Wang
    • Wen‑Jie Zhou
    • Li‑Ping Jin
    • Ming‑Qing Li
  • View Affiliations / Copyright

    Affiliations: Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University, Shanghai Medical College, Shanghai 200011, P.R. China, Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China, Clinical and Translational Research Center, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2869-2878
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    Published online on: December 12, 2017
       https://doi.org/10.3892/mmr.2017.8267
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Abstract

Embryo implantation is essential for a successful pregnancy, and leads to the decidualization of endometrial stromal cells (ESCs) in the secretory phase of the menstrual cycle. It has previously been demonstrated that decidual stromal cells (DSCs) co‑express interleukin (IL)‑25/IL‑17RB and that IL‑25 further promotes the proliferation of DSCs via activating c‑Jun n‑terminal kinase and protein kinase B signals, therefore the present study primarily focused on the role of IL‑25 in the process of decidualization in vitro. It was demonstrated that the expression of IL‑25/IL‑17RB in ESCs was decreased compared with DSCs. In addition, following decidualization, the expression levels of IL‑25/IL‑17RB in ESCs were significantly elevated. Recombinant human (rh) IL‑25 promoted the decidualization of ESCs in the presence of 8‑bromoadenosine 3',5'‑cyclic monophosphate sodium salt and 6α‑methyl17α‑acetoxyprogesterone, which was partially inhibited by anti‑human IL‑25 neutralizing antibody (anti‑IL‑25) or anti‑IL‑17RB. In addition, decidual natural killer (dNK) cells not only secreted IL‑25, however also further accelerated the decidualization in vitro. Therefore, these findings indicated that ESCs differentiate into DSCs in the presence of ovarian hormones, resulting in the upregulation of IL‑25/IL‑17RB expression in ESCs. Furthermore, IL‑25 secreted by ESCs and dNK cells further facilitates the decidualization of ESCs, which may form a positive feedback mechanism at the maternal‑fetal interface and thus contribute to the establishment and maintenance of normal pregnancy.
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View References

1 

Zhang S, Lin H, Kong S, Wang S, Wang H, Wang H and Armant DR: Physiological and molecular determinants of embryo implantation. Mol Aspects Med. 34:939–980. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Tang B, Guller S and Gurpide E: Mechanisms of human endometrial stromal cell decidualization. Ann N Y Acad Sci. 734:19–25. 1994. View Article : Google Scholar : PubMed/NCBI

3 

Salamonsen LA, Dimitriadis E, Jones RL and Nie G: Complex regulation of decidualization: A role for cytokines and proteases-a review. Placenta. 24 Suppl A:S76–S85. 2003. View Article : Google Scholar : PubMed/NCBI

4 

Maruyama T and Yoshimura Y: Molecular and cellular mechanisms for differentiation and regeneration of the uterine endometrium. Endocr J. 55:795–810. 2008. View Article : Google Scholar : PubMed/NCBI

5 

Matsumoto K, Yamauchi N, Watanabe R, Oozono S, Kubota K, Nishimura K, Wood C, Soh T, Kizaki K and Hattori MA: In vitro decidualization of rat endometrial stromal cells. Cell Tissue Res. 335:575–583. 2009. View Article : Google Scholar : PubMed/NCBI

6 

Salamonsen LA, Nie G, Hannan NJ and Dimitriadis E: Society for reproductive biology Founders' Lecture 2009. Preparing fertile soil: The importance of endometrial receptivity. Reprod Fertil Dev. 21:923–934. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Dimitriadis E, White CA, Jones RL and Salamonsen LA: Cytokines, chemokines and growth factors in endometrium related to implantation. Hum Reprod Update. 11:613–630. 2005. View Article : Google Scholar : PubMed/NCBI

8 

Koot YE, Boomsma CM, Eijkemans MJ, Lentjes EG and Macklon NS: Recurrent pre-clinical pregnancy loss is unlikely to be a ‘cause’ of unexplained infertility. Hum Reprod. 26:2636–2641. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Aplin JD: Developmental cell biology of human villous trophoblast: Current research problems. Int J Dev Biol. 54:323–329. 2010. View Article : Google Scholar : PubMed/NCBI

10 

Knöfler M: Critical growth factors and signalling pathways controlling human trophoblast invasion. Int J Dev Biol. 54:269–280. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Popovici RM, Kao LC and Giudice LC: Discovery of new inducible genes in in vitro decidualized human endometrial stromal cells using microarray technology. Endocrinology. 141:3510–3513. 2000. View Article : Google Scholar : PubMed/NCBI

12 

Gellersen B and Brosens J: Cyclic AMP and progesterone receptor cross-talk in human endometrium: A decidualizing affair. J Endocrinol. 178:357–372. 2003. View Article : Google Scholar : PubMed/NCBI

13 

Brosens JJ, Hayashi N and White JO: Progesterone receptor regulates decidual prolactin expression in differentiating human endometrial stromal cells. Endocrinology. 140:4809–4820. 1999. View Article : Google Scholar : PubMed/NCBI

14 

Fort MM, Cheung J, Yen D, Li J, Zurawski SM, Lo S, Menon S, Clifford T, Hunte B, Lesley R, et al: IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity. 15:985–995. 2001. View Article : Google Scholar : PubMed/NCBI

15 

Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, Lv Z, Fan Y, An Y, Wang YH, et al: T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma. Proc Natl Acad Sci USA. 108:pp. 1579–1584. 2011; View Article : Google Scholar : PubMed/NCBI

16 

Wang W, Fan YQ, Lv Z, Yao XJ, Wang W, Huang KW, Meng Q, Fang CL, Lee TH, Corrigan CJ, et al: Interleukin-25 promotes basic fibroblast growth factor expression by human endothelial cells through interaction with IL-17RB, but not IL-17RA. Clin Exp Allergy. 42:1604–1614. 2012. View Article : Google Scholar : PubMed/NCBI

17 

Giannubilo SR, Landi B, Pozzi V, Sartini D, Cecati M, Stortoni P, Corradetti A, Saccucci F, Tranquilli AL and Emanuelli M: The involvement of inflammatory cytokines in the pathogenesis of recurrent miscarriage. Cytokine. 58:50–56. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Wang Y, Zhang Y, Li MQ, Fan DX, Wang XH, Li DJ and Jin LP: Interleukin-25 induced by human chorionic gonadotropin promotes the proliferation of decidual stromal cells by activation of JNK and AKT signal pathways. Fertil Steril. 102:257–263. 2014. View Article : Google Scholar : PubMed/NCBI

19 

Mei J, Xie XX, Li MQ, Wei CY, Jin LP, Li DJ and Zhu XY: Indoleamine 2,3-dioxygenase-1 (IDO1) in human endometrial stromal cells induces macrophage tolerance through interleukin-33 in the progression of endometriosis. Int J Clin Exp Pathol. 7:2743–2757. 2014.PubMed/NCBI

20 

Fu Q, Tao Y, Piao H, Du MR and Li DJ: Trophoblasts and decidual stromal cells regulate decidual NK cell functions via interaction between collagen and LAIR-1. Am J Reprod Immunol. 71:368–378. 2014. View Article : Google Scholar : PubMed/NCBI

21 

Ramathal CY, Bagchi IC, Taylor RN and Bagchi MK: Endometrial decidualization: Of mice and men. Semin Reprod Med. 28:17–26. 2010. View Article : Google Scholar : PubMed/NCBI

22 

Salker M, Teklenburg G, Molokhia M, Lavery S, Trew G, Aojanepong T, Mardon HJ, Lokugamage AU, Rai R, Landles C, et al: Natural selection of human embryos: Impaired decidualization of endometrium disables embryo-maternal interactions and causes recurrent pregnancy loss. PLoS One. 5:e102872010. View Article : Google Scholar : PubMed/NCBI

23 

Telgmann R and Gellersen B: Marker genes of decidualization: Activation of the decidual prolactin gene. Hum Reprod Update. 4:472–479. 1998. View Article : Google Scholar : PubMed/NCBI

24 

Pohnke Y, Kempf R and Gellersen B: CCAAT/enhancer-binding proteins are mediators in the protein kinase A-dependent activation of the decidual prolactin promoter. J Biol Chem. 274:24808–24818. 1999. View Article : Google Scholar : PubMed/NCBI

25 

Kim JJ, Taylor HS, Akbas GE, Foucher I, Trembleau A, Jaffe RC, Fazleabas AT and Unterman TG: Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells. Biol Reprod. 68:24–30. 2003. View Article : Google Scholar : PubMed/NCBI

26 

Grinius L, Kessler C, Schroeder J and Handwerger S: Forkhead transcription factor FOXO1A is critical for induction of human decidualization. J Endocrinol. 189:179–187. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Lynch VJ, Brayer K, Gellersen B and Wagner GP: HoxA-11 and FOXO1A cooperate to regulate decidual prolactin expression: Towards inferring the core transcriptional regulators of decidual genes. PLoS One. 4:e68452009. View Article : Google Scholar : PubMed/NCBI

28 

Gellersen B, Kempf R, Telgmann R and DiMattia GE: Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma. Mol Endocrinol. 8:356–373. 1994. View Article : Google Scholar : PubMed/NCBI

29 

Binart N, Helloco C, Ormandy CJ, Barra J, Clément-Lacroix P, Baran N and Kelly PA: Rescue of preimplantatory egg development and embryo implantation in prolactin receptor-deficient mice after progesterone administration. Endocrinology. 141:2691–2697. 2000. View Article : Google Scholar : PubMed/NCBI

30 

Bao L, Tessier C, Prigent-Tessier A, Li F, Buzzio OL, Callegari EA, Horseman ND and Gibori G: Decidual prolactin silences the expression of genes detrimental to pregnancy. Endocrinology. 148:2326–2334. 2007. View Article : Google Scholar : PubMed/NCBI

31 

Julkunen M, Koistinen R, Suikkari AM, Seppälä M and Jänne OA: Identification by hybridization histochemistry of human endometrial cells expressing mRNAs encoding a uterine beta-lactoglobulin homologue and insulin-like growth factor-binding protein-1. Mol Endocrinol. 4:700–707. 1990. View Article : Google Scholar : PubMed/NCBI

32 

Rutanen EM, Partanen S and Pekonen F: Decidual transformation of human extrauterine mesenchymal cells is associated with the appearance of insulin-like growth factor-binding protein-1. J Clin Endocrinol Metab. 72:27–31. 1991. View Article : Google Scholar : PubMed/NCBI

33 

Irwin JC and Giudice LC: Insulin-like growth factor binding protein-1 binds to placental cytotrophoblast alpha5beta1 integrin and inhibits cytotrophoblast invasion into decidualized endometrial stromal cultures. Growth Horm IGF Res. 8:21–31. 1998. View Article : Google Scholar : PubMed/NCBI

34 

Jones JI, Gockerman A, Busby WH Jr, Wright G and Clemmons DR: Insulin-like growth factor-binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence. Proc Natl Acad Sci USA. 90:pp. 10553–10557. 1993; View Article : Google Scholar : PubMed/NCBI

35 

Leitao B, Jones MC, Fusi L, Higham J, Lee Y, Takano M, Goto T, Christian M, Lam EW and Brosens JJ: Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals. FASEB J. 24:1541–1551. 2010. View Article : Google Scholar : PubMed/NCBI

36 

Fabi F and Asselin E: Expression, activation, and role of AKT isoforms in the uterus. Reproduction. 148:R85–R95. 2014. View Article : Google Scholar : PubMed/NCBI

37 

Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M and Feramisco JR: Signal transduction through the cAMP-dependent protein kinase. Mol Cell Biochem 127–128. 1–186. 1993.

38 

Kaupp UB and Seifert R: Cyclic nucleotide-gated ion channels. Physiol Rev. 82:769–824. 2002. View Article : Google Scholar : PubMed/NCBI

39 

Bos JL: Epac proteins: Multi-purpose cAMP targets. Trends Biochem Sci. 31:680–686. 2006. View Article : Google Scholar : PubMed/NCBI

40 

Simrick S, Schindler RF, Poon KL and Brand T: Popeye domain-containing proteins and stress-mediated modulation of cardiac pacemaking. Trends Cardiovasc Med. 23:257–263. 2013. View Article : Google Scholar : PubMed/NCBI

41 

Ran WZ, Dong L, Tang CY, Zhou Y, Sun GY, Liu T, Liu YP and Guan CX: Vasoactive intestinal peptide suppresses macrophage-mediated inflammation by downregulating interleukin-17A expression via PKA- and PKC-dependent pathways. Int J Exp Pathol. 96:269–275. 2015. View Article : Google Scholar : PubMed/NCBI

42 

Rabot M, Tabiasco J, Polgar B, Aguerre-Girr M, Berrebi A, Bensussan A, Strbo N, Rukavina D and Le Bouteiller P: HLA class I/NK cell receptor interaction in early human decidua basalis: Possible functional consequences. Chem Immunol Allergy. 89:72–83. 2005. View Article : Google Scholar : PubMed/NCBI

43 

Bulmer JN, Morrison L, Longfellow M, Ritson A and Pace D: Granulated lymphocytes in human endometrium: Histochemical and immunehistochemical studies. Hum Reprod. 6:791–798. 1991. View Article : Google Scholar : PubMed/NCBI

44 

Loke YW, King A and Burrows TD: Decidua in human implantation. Hum Reprod. Suppl 2:S14–S21. 1995. View Article : Google Scholar

45 

Lukassen HG, Joosten I, van Cranenbroek B, van Lierop MJ, Bulten J, Braat DD and van der Meer A: Hormonal stimulation for IVF treatment positively affects the CD56bright/CD56dim NK cell ratio of the endometrium during the window of implantation. Mol Hum Reprod. 10:513–520. 2004. View Article : Google Scholar : PubMed/NCBI

46 

Leonard S, Murrant C, Tayade C, van den Heuvel M, Watering R and Croy BA: Mechanisms regulating immune cell contributions to spiral artery modification-facts and hypotheses-a review. Placenta. 27 Suppl A:S40–S46. 2006. View Article : Google Scholar : PubMed/NCBI

47 

Jabrane-Ferrat N and Siewiera J: The up side of decidual natural killer cells: New developments in immunology of pregnancy. Immunology. 141:490–497. 2014. View Article : Google Scholar : PubMed/NCBI

48 

Hanna J, Goldman-Wohl D, Hamani Y, Avraham I, Greenfield C, Natanson-Yaron S, Prus D, Cohen-Daniel L, Arnon TI, Manaster I, et al: Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med. 12:1065–1074. 2006. View Article : Google Scholar : PubMed/NCBI

49 

Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, et al: Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med. 350:672–683. 2004. View Article : Google Scholar : PubMed/NCBI

50 

Chappell LC, Duckworth S, Seed PT, Griffin M, Myers J, Mackillop L, Simpson N, Waugh J, Anumba D, Kenny LC, et al: Diagnostic accuracy of placental growth factor in women with suspected preeclampsia: A prospective multicenter study. Circulation. 128:2121–2131. 2013. View Article : Google Scholar : PubMed/NCBI

51 

Ashkar AA, Di Santo JP and Croy BA: Interferon gamma contributesto initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. J Exp Med. 192:259–270. 2000. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang Y, Wang Y, Wang XH, Zhou WJ, Jin LP and Li MQ: Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25. Mol Med Rep 17: 2869-2878, 2018.
APA
Zhang, Y., Wang, Y., Wang, X., Zhou, W., Jin, L., & Li, M. (2018). Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25. Molecular Medicine Reports, 17, 2869-2878. https://doi.org/10.3892/mmr.2017.8267
MLA
Zhang, Y., Wang, Y., Wang, X., Zhou, W., Jin, L., Li, M."Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25". Molecular Medicine Reports 17.2 (2018): 2869-2878.
Chicago
Zhang, Y., Wang, Y., Wang, X., Zhou, W., Jin, L., Li, M."Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25". Molecular Medicine Reports 17, no. 2 (2018): 2869-2878. https://doi.org/10.3892/mmr.2017.8267
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang Y, Wang Y, Wang XH, Zhou WJ, Jin LP and Li MQ: Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25. Mol Med Rep 17: 2869-2878, 2018.
APA
Zhang, Y., Wang, Y., Wang, X., Zhou, W., Jin, L., & Li, M. (2018). Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25. Molecular Medicine Reports, 17, 2869-2878. https://doi.org/10.3892/mmr.2017.8267
MLA
Zhang, Y., Wang, Y., Wang, X., Zhou, W., Jin, L., Li, M."Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25". Molecular Medicine Reports 17.2 (2018): 2869-2878.
Chicago
Zhang, Y., Wang, Y., Wang, X., Zhou, W., Jin, L., Li, M."Crosstalk between human endometrial stromal cells and decidual NK cells promotes decidualization in vitro by upregulating IL‑25". Molecular Medicine Reports 17, no. 2 (2018): 2869-2878. https://doi.org/10.3892/mmr.2017.8267
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