|
1
|
Arden N, Blanco F, Cooper C, Guermazi A,
Hayashi D, Hunter D, Javaid MK, Rannou F, Roemer FW and Reginster
JY: Atlas of osteosteoarthritis. Springer Healthcare Ltd. 69–82.
2014.
|
|
2
|
World Health Organization, . The Global
Burden of Disease2004 Update. World Health Organization; Geneva:
2008
|
|
3
|
Cross M, Smith E, Hoy D, Nolte S, Ackerman
I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, et al:
The global burden of hip and knee osteoarthritis: Estimates from
the global burden of disease 2010 study. Ann Rheum Dis.
73:1323–1330. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
March L, Smith EU, Hoy DG, Cross MJ,
Sanchez-Riera L, Blyth F, Buchbinder R, Vos T and Woolf AD: Burden
of disability due to musculoskeletal (MSK) disorders. Best Pract
Res Clin Rheumatol. 28:353–366. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Chu CR, Millis MB and Olson SA:
Osteoarthritis: From Palliation to Prevention: AOA Critical Issues.
J Bone Joint Surg Am. 96:e1302014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Glyn-Jones S, Palmer AJ, Agricola R, Price
AJ, Vincent TL, Weinans H and Carr AJ: Osteoarthritis. Lancet.
386:376–387. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Sanchez-Adams J, Leddy HA, McNulty AL,
O'Conor CJ and Guilak F: The mechanobiology of articular cartilage:
Bearing the burden of osteoarthritis. Curr Rheumatol Rep.
16:4512014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Maroudas AI: Balance between swelling
pressure and collagen tension in normal and degenerate cartilage.
Nature. 260:808–809. 1976. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chou MC, Tsai PH, Huang GS, Lee HS, Lee
CH, Lin MH, Lin CY and Chung HW: Correlation between the MR T2
value at 4.7 T and relative water content in articular cartilage in
experimental osteoarthritis induced by ACL transection.
Osteoarthritis Cartilage. 17:441–447. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Eppert K, Scherer SW, Ozcelik H, Pirone R,
Hoodless P, Kim H, Tsui LC, Bapat B, Gallinger S, Andrulis IL, et
al: MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related
protein that is functionally mutated in colorectal carcinoma. Cell.
86:543–552. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Riggins GJ, Thiagalingam S, Rozenblum E,
Weinstein CL, Kern SE, Hamilton SR, Willson JK, Markowitz SD,
Kinzler KW and Vogelstein B: Mad-related genes in the human. Nat
Genet. 13:347–349. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Long E, Motwani R, Reece D, Pettit N,
Hepworth J, Wong P, Reynolds P and Seegmiller R: The role of TGF-β1
in osteoarthritis of the temporomandibular joint in two genetic
mouse models. Arch Oral Biol. 67:68–73. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Madej W, Buma P and van der Kraan P:
Inflammatory conditions partly impair the mechanically mediated
activation of Smad2/3 signaling in articular cartilage. Arthritis
Res Ther. 18:1462016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ambros V: The functions of animal
microRNAs. Nature. 431:350–355. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Dahaghin S, Bierma-Zeinstra SM, Ginai AZ,
Pols HA, Hazes JM and Koes BW: Prevalence and pattern of
radiographic hand osteoarthritis and association with pain and
disability. Ann Rheum Dis. 64:682–687. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Davidson Blaney EN, Vitters EL, van der
Kraan PM and van den Berg WB: Expression of transforming growth
factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P
in spontaneous and instability-induced osteoarthritis: Role in
cartilage degradation, chondrogenesis and osteophyte formation. Ann
Rheum Dis. 65:1414–1421. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Min JL, Meulenbelt I, Riyazi N,
Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, Pols HA, van
Duijn CM and Slagboom PE: Association of the Frizzled-related
protein gene with symptomatic osteoarthritis at multiple sites.
Arthritis Rheum. 52:1077–1080. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Iliopoulos D, Malizos KN, Oikonomou P and
Tsezou A: Integrative microRNA and proteomic approaches identify
novel osteoarthritis genes and their collaborative metabolic and
inflammatory networks. PLoS One. 3:e37402008. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Sumiyoshi K, Kubota S, Ohgawara T, Kawata
K, Nishida T, Shimo T, Yamashiro T and Takigawa M: Identification
of miR-1 as a micro RNA that supports late-stage differentiation of
growth cartilage cells. Biochem Biophys Res Commun. 402:286–290.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Davidson Blaney EN, van der Kraan PM and
van den Berg WB: TGF-beta and osteoarthritis. Osteoarthritis
Cartilage. 15:597–604. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Itayem R, Mengarelli-Widholm S, Hulth A
and Reinholt FP: Ultrastructural studies on the effect of
transforming growth factor 1 on rat articular cartilage. Apmis.
105:221–218. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Finnson KW, Parker WL, Ten Dijke P,
Thorikay M and Philip A: ALK1 opposes ALK5/Smad3 signaling and
expression of extracellular matrix components in human
chondrocytes. J Bone Miner Res. 23:896–906. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Wang W, Song B, Anbarchian T, Shirazyan A,
Sadik JE and Lyons KM: Smad2 and Smad3 regulate chondrocyte
proliferation and differentiation in the growth plate. PLoS Genet.
12:e10063522016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhu Y, Tao H, Jin C, Liu Y, Lu X, Hu X and
Wang X: Transforming growth factor-β1 induces type II collagen and
aggrecan expression via activation of extracellular
signal-regulated kinase 1/2 and Smad2/3 signaling pathways. Mol Med
Rep. 12:5573–9. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Louafi F, Martinez-Nunez RT and
Sanchez-Elsner T: MicroRNA-155 targets SMAD2 and modulates the
response of macrophages to transforming growth Factor-{beta}. J
Biol Chem. 285:41328–41336. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang J, Tian X, Han R, Zhang X, Wang X,
Shen H, Xue L, Liu Y, Yan X, Shen J, et al: Downregulation of
miR-486-5p contributes to tumor progression and metastasis by
targeting protumorigenic ARHGAP5 in lung cancer. Oncogene.
33:1181–1189. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Pang W, Tian X, Bai F, Han R, Wang J, Shen
H, Zhang X, Liu Y, Yan X, Jiang F and Xing L: Pim-1 kinase is a
target of miR-486-5p and eukaryotic translation initiation factor
4E, and plays a critical role in lung cancer. Mol Cancer.
13:2402014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Liu B, Sun J, Lei X, Zhu Z, Pei C and Qin
L: MicroRNA-486-5p suppresses TGF-β2-induced proliferation,
invasion and epithelial-mesenchymal transition of lens epithelial
cells by targetingSmad2. J Biosci. 42:575–584. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kong R, Gao J, Si Y and Zhao D:
Combination of circulating miR-19b-3p, miR-122-5p and miR-486-5p
expressions correlates with risk and disease severity of knee
osteoarthritis. Am J Transl Res. 9:2852–2864. 2017.PubMed/NCBI
|
