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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2018 Volume 18 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Vitamin K‑dependent proteins involved in bone and cardiovascular health (Review)

Lianpu Wen, Jiepeng Chen, Lili Duan, Shuzhuang Li
Pages: 3-15
Published online on: 27 April 2018

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Article Open Access

Long noncoding RNA KCNQ1OT1 promotes proliferation and epithelial‑mesenchymal transition by regulation of SMAD4 expression in lens epithelial cells

Bin Chen, Jian Ma, Chunwei Li, Yong Wang
Pages: 16-24
Published online on: 08 May 2018

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Article Open Access

Effect of combined chondroitinase ABC and hyperbaric oxygen therapy in a rat model of spinal cord injury

Xiaoyang Liu, Jiefeng Wang, Guangkuo Li, Honglin Lv
Pages: 25-30
Published online on: 26 April 2018

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Article Open Access

Identification of genes and pathways associated with multiple organ dysfunction syndrome by microarray analysis

Changwei Gu, Wanhai Qiao, Lina Wang, Minmin Li , Kang Song
Pages: 31-40
Published online on: 04 May 2018

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Article Open Access

Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms

Emina Vorkapic, Anne Kunath, Dick Wågsäter
Pages: 41-48
Published online on: 27 April 2018

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Article Open Access

Serum proteomic analysis of the anti‑arthritic effects of sinomenine on rats with collagen‑induced arthritis

Xin Qian, Zhiming Zhao, Wei Shang, Zhihan Xu, Beibei Zhang, Hui Cai
Pages: 49-58
Published online on: 03 May 2018

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Article Open Access

Proteomic analysis of chick retina during early recovery from lens‑induced myopia

Yun Yun Zhou, Rachel Ka Man Chun, Jian Chao Wang, Bing Zuo, King Kit Li, Thomas Chuen Lam, Quan Liu, Chi‑Ho To
Pages: 59-66
Published online on: 03 May 2018

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Article Open Access

Screening of differentially expressed genes in male idiopathic osteoporosis via RNA sequencing

Li Feng, Yan Wang, Jing Zhou, Baofang Tian, Bo Xia
Pages: 67-76
Published online on: 07 May 2018

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Article Open Access

CD8+ T cells with high TGF‑β1 expression cause lymph node fibrosis following HIV infection

Lei Huang, Jianning Deng, Wen Xu, Hongbo Wang, Lei Shi, Fengyao Wu, Dan Wu, Weimin Nei, Min Zhao, Panyong Mao, Xianzhi Zhou
Pages: 77-86
Published online on: 03 May 2018

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Article Open Access

Lysophosphatidic acid enhances neointimal hyperplasia following vascular injury through modulating proliferation, autophagy, inflammation and oxidative stress

Xuhui Shen, Jianjun Zou, Fuyong Li, Tianhe Zhang, Tongqi Guo
Pages: 87-96
Published online on: 27 April 2018

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Article Open Access

Porphyromonas gingivalis induced inflammatory responses and promoted apoptosis in lung epithelial cells infected with H1N1 via the Bcl‑2/Bax/Caspase‑3 signaling pathway

Yongju Chen, Rui Zhou, Zhe Yi, Yonggang Li, Ying Fu, Yibo Zhang, Ping Li, Xin Li, Yaping Pan
Pages: 97-104
Published online on: 07 May 2018

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Article Open Access

miR‑23a suppresses pancreatic cancer cell progression by inhibiting PLK‑1 expression Corrigendum in /10.3892/mmr.2022.12738 Retraction in /10.3892/mmr.2025.13475

Bin Chen, Akao Zhu, Lei Tian, Ying Xin, Xinchun Liu, Yunpeng Peng, Jingjing Zhang, Yi Miao, Jishu Wei
Pages: 105-112
Published online on: 27 April 2018

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Article Open Access

Placental protein 14 as a potential biomarker for diagnosis of preterm premature rupture of membranes

Yanyun Wang, Haibo Luo, Guanglu Che, Yanqin Li, Jun Gao, Qiongli Yang, Bin Zhou, Linbo Gao, Tao Wang, Yujie Liang, Lin Zhang
Pages: 113-122
Published online on: 03 May 2018

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Article Open Access

Genome‑wide DNA methylation profiling in a rat model with vascular dementia

Jong‑Min Park, Yoon Ju Kim, Min Kyung Song, Jae‑Min Lee, Youn‑Jung Kim
Pages: 123-130
Published online on: 08 May 2018

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Article Open Access

Anti‑metastatic effects of Aidi on human esophageal squamous cell carcinoma by inhibiting epithelial‑mesenchymal transition and angiogenesis

Qingtong Shi, Yali Diao, Feng Jin, Zhiyan Ding
Pages: 131-138
Published online on: 04 May 2018

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Article Open Access

Alterations in mRNA profiles of trastuzumab‑resistant Her‑2‑positive breast cancer

Bin Zhao, Yang Zhao, Yan Sun, Haitao Niu, Long Sheng, Dongfang Huang, Li Li
Pages: 139-146
Published online on: 07 May 2018

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Article Open Access

Salidroside inhibits the proliferation and migration of gastric cancer cells via suppression of Src‑associated signaling pathway activation and heat shock protein 70 expression

Zhilin Qi, Tuo Tang, Lili Sheng, Yunfei Ma, Yinhua Liu, Liang Yan, Shimei Qi, Liefeng Ling, Yao Zhang
Pages: 147-156
Published online on: 03 May 2018

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Article Open Access

Knockdown of Ran GTPase expression inhibits the proliferation and migration of breast cancer cells

Chenyi Sheng, Jian Qiu, Yingying Wang, Zhixian He, Hua Wang, Qingqing Wang, Yeqing Huang, Lianxin Zhu, Feng Shi, Yingying Chen, Shiyao Xiong, Zhen Xu, Qichao Ni
Pages: 157-168
Published online on: 03 May 2018

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Article Open Access

Immunotherapy by targeting of VGKC complex for seizure control and prevention of cognitive impairment in a mouse model of epilepsy

Zhiliang Fan, Xiaojuan Feng, Zhigang Fan, Xingyuan Zhu, Shaohua Yin
Pages: 169-178
Published online on: 09 May 2018

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Article Open Access

Apoptosis of CD19+ chimeric antigen receptor T cells after treatment with chemotherapeutic agents

Wenfang Yi, Fuyu Pei, Wen Ding, Mo Yang, Guang Lin, Cheng Zhang, Xuedong Wu, Yuelin He, Xiaoqin Feng, Huanying Liu, Zhiyong Peng, Chunfu Li
Pages: 179-183
Published online on: 02 May 2018

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Article Open Access

Anesthetic effects of isoflurane and the molecular mechanism underlying isoflurane‑inhibited aggressiveness of hepatic carcinoma

Jing Hu, Jingli Hu, Hongmei Jiao, Qingguo Li
Pages: 184-192
Published online on: 02 May 2018

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Article Open Access

Actinidia chinensis planch polysaccharide protects against hypoxia‑induced apoptosis of cardiomyocytes in vitro

Qiang Wang, Yunfa Xu, Ying Gao, Qi Wang
Pages: 193-201
Published online on: 03 May 2018

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Article Open Access

MEF2‑activated long non‑coding RNA PCGEM1 promotes cell proliferation in hormone‑refractory prostate cancer through downregulation of miR‑148a

Shibao Zhang, Zongwu Li, Longyang Zhang, Zhonghua Xu
Pages: 202-208
Published online on: 04 May 2018

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Article Open Access

Repair of urethral defects by an adipose mesenchymal stem cell‑porous silk fibroin material

Binqiang Tian, Lujie Song, Tao Liang, Zuowei Li, Xuxiao Ye, Qiang Fu, Yonghui Li
Pages: 209-215
Published online on: 09 May 2018

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Article Open Access

High glucose upregulates myosin light chain kinase to induce microfilament cytoskeleton rearrangement in hippocampal neurons

Liying Zhu, Chengcheng Li, Guiqin Du, Meixiu Pan, Guoqi Liu, Wei Pan, Xing Li
Pages: 216-222
Published online on: 03 May 2018

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Article Open Access

Detection of miR‑29a in plasma of patients with lumbar spinal stenosis and the clinical significance

Genai Zhang, Wenping Zhang, Yu Hou, Yingchun Chen, Jipeng Song, Lixiang Ding
Pages: 223-229
Published online on: 03 May 2018

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Article Open Access

A gene interaction network‑based method to measure the common and heterogeneous mechanisms of gynecological cancer

Mingyuan Wang, Liping Li, Jinglan Liu, Jinjin Wang
Pages: 230-242
Published online on: 03 May 2018

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Article Open Access

Chemoresistance‑related long non‑coding RNA expression profiles in human breast cancer cells Erratum in /10.3892/mmr.2019.10003

Lei Huang, Lihua Zeng, Jiahui Chu, Pengfei Xu, Mingming Lv, Juan Xu, Juan Wen, Wenqu Li, Luyu Wang, Xiaowei Wu, Ziyi Fu, Hui Xie, Shui Wang
Pages: 243-253
Published online on: 27 April 2018

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Case Report Open Access

COL2A1 mutation (c.3508G>A) leads to avascular necrosis of the femoral head in a Chinese family: A case report

Fang Liu, Zhizheng Xiong, Qi Liu, Jinxi Hu, Wenhua Li, Na Zhang
Pages: 254-260
Published online on: 07 May 2018

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Article Open Access

A novel PNPLA6 compound heterozygous mutation identified in a Chinese patient with Boucher‑Neuhäuser syndrome

Ruizhi Zheng, Yaguang Zhao, Jiayu Wu, Yuanmei Wang, Jian‑Ling Liu, Zhi‑Ling Zhou, Xiao‑Tao Zhou, Dan‑Na Chen, Wei‑Hua Liao, Jia‑Da Li
Pages: 261-267
Published online on: 03 May 2018

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Article Open Access

EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain‑1 and caspase‑3

Mei Yang, Wei Chen, Yu Zhang, Rui Yang, Yiru Wang, Hongbin Yuan
Pages: 268-278
Published online on: 09 May 2018

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Article Open Access

Identification of a 5‑lncRNA signature‑based risk scoring system for survival prediction in colorectal cancer

Liqiang Gu, Jun Yu, Qing Wang, Bin Xu, Liechen Ji, Lin Yu, Xipeng Zhang, Hui Cai
Pages: 279-291
Published online on: 03 May 2018

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Article Open Access

Dishevelled‑2 modulates osteogenic differentiation of human synovial fibroblasts in osteoarthritis

Lihua Zhang, Luan Luan, Yingying Ma
Pages: 292-298
Published online on: 04 May 2018

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Article Open Access

Genome‑wide identification of long noncoding RNAs in CCl4‑induced liver fibrosis via RNA sequencing

Zhenghua Gong, Jialin Tang, Tianxin Xiang, Jiayu Lin, Chaowen Deng, Yanzhong Peng, Jie Zheng, Guoxin Hu
Pages: 299-307
Published online on: 07 May 2018

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Article Open Access

Human HLA‑F adjacent transcript 10 promotes the formation of cancer initiating cells and cisplatin resistance in bladder cancer Retraction in /10.3892/mmr.2024.13187

Chen Li, Zhenfan Wang, Ninghan Feng, Jian Dong, Xiaoyan Deng, Yin Yue, Yuehong Guo, Jianquan Hou
Pages: 308-314
Published online on: 09 May 2018

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Article Open Access

Gas‑filled ultrasound microbubbles enhance the immunoactivity of the HSP70‑MAGEA1 fusion protein against MAGEA1‑expressing tumours

Xing Gao, Yang Nan, Yuan Yuan, Xue Gong, Yuanyuan Sun, Huihui Zhou, Yujin Zong, Lijun Zhang, Ming Yu
Pages: 315-321
Published online on: 09 May 2018

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Article Open Access

α‑synuclein induces apoptosis of astrocytes by causing dysfunction of the endoplasmic reticulum‑Golgi compartment

Mei Liu, Lixia Qin, Lili Wang, Jieqiong Tan, Hainan Zhang, Jianguang Tang, Xiangmin Shen, Liming Tan, Chunyu Wang
Pages: 322-332
Published online on: 09 May 2018

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Article Open Access

Bioinformatics analysis of microarray data to reveal the pathogenesis of brain ischemia

Jiaxuan He, Ya Gao, Gang Wu, Xiaoming Lei, Yong Zhang, Weikang Pan, Hui Yu
Pages: 333-341
Published online on: 09 May 2018

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Article Open Access

Toll‑Like receptor 4 promotes the phosphorylation of CRMP2 via the activation of Rho‑kinase in MCAO rats

Xue‑Bo Li, Ming‑Xia Ding, Chun‑Li Ding, Liang‑Liang Li, Jinzhou Feng, Xiao‑Jun Yu
Pages: 342-348
Published online on: 03 May 2018

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Article Open Access

Overexpression of Annexin A1 protects against benzo[a]pyrene‑induced bronchial epithelium injury

Yanfei Cui, Shengya Yang
Pages: 349-357
Published online on: 09 May 2018

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Article

miR‑24 regulates angiogenesis in gliomas

Dongwei Dai, Wei Huang, Qiong Lu, Hanchun Chen, Jianmin Liu, Bo Hong
Pages: 358-368
Published online on: 04 May 2018

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Article

TRIM24 siRNA induced cell apoptosis and reduced cell viability in human nasopharyngeal carcinoma cells

Peng Wang, Na Shen, Danzheng Liu, Xianhui Ning, Daquan Wu, Xinsheng Huang
Pages: 369-376
Published online on: 02 May 2018

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Article

Downregulation of N‑Myc inhibits neuroblastoma cell growth via the Wnt/β‑catenin signaling pathway

Yingge Wang, Shan Gao, Weiguang Wang, Yuting Xia, Jingyan Liang
Pages: 377-384
Published online on: 03 May 2018

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Article

Significant role of microRNA‑219‑5p in diabetic retinopathy and its mechanism of action

Junying Zhao, Sha Gao, Yanji Zhu, Xi Shen
Pages: 385-390
Published online on: 08 May 2018

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Article

Silencing of URG11 expression inhibits the proliferation and epithelial‑mesenchymal transition in benign prostatic hyperplasia cells via the RhoA/ROCK1 pathway

Guanying Zhang, Feng Zhu, Guangye Han, Zeyu Li, Quanfeng Yu, Zhenhui Li, Jianchang Li
Pages: 391-398
Published online on: 08 May 2018

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Article

LIN28A inhibits lysosome‑associated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells

Peng Pan, Ting Chen, Yanmin Zhang, Zhengyu Qi, Jie Qin, Guanghui Cui, Xin Guo
Pages: 399-406
Published online on: 03 May 2018

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Article

Anticancer effects of isofraxidin against A549 human lung cancer cells via the EGFR signaling pathway

Han Zhang, Qian‑Qian Feng, Jian‑Hua Gong, Jing‑Ping Ma
Pages: 407-414
Published online on: 03 May 2018

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Article

Locomotor activity of rats with SCI is improved by dexmedetomidine by targeting the expression of inflammatory factors

Wei‑Guo Wang, Lin Wang, Zhen‑Hua Jiao, Bin Xue, Zhan‑Wang Xu
Pages: 415-420
Published online on: 26 April 2018

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Article

C‑Myc inhibitor 10058‑F4 increases the efficacy of dexamethasone on acute lymphoblastic leukaemia cells

Mei Lv, Yi Wang, Wenmiao Wu, Shujun Yang, Huiling Zhu, Bei Hu, Ying Chen, Cong Shi, Yi Zhang, Qitian Mu, Guifang Ouyang
Pages: 421-428
Published online on: 27 April 2018

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Article

Angiotensin II inhibits the protein expression of ZO‑1 in vascular endothelial cells by downregulating VE‑cadherin

Longbin Liu, Liping Meng, Peng Zhang, Hui Lin, Jufang Chi, Fang Peng, Hangyuan Guo
Pages: 429-434
Published online on: 08 May 2018

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Article

Identification of a VHL gene mutation in a Chinese family with Von Hippel‑Lindau syndrome

Zhengwen He, Lu Xia, Zhiyong Deng, Aojie Lian, Zhengmao Hu, Bin Li
Pages: 435-440
Published online on: 04 May 2018

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Article

miR‑188 suppresses tumor progression by targeting SOX4 in pediatric osteosarcoma

Lu Pan, Lingxin Meng, Feng Liang, Li Cao
Pages: 441-446
Published online on: 09 May 2018

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Article

Pulsed electromagnetic fields inhibit osteoclast differentiation in RAW264.7 macrophages via suppression of the protein kinase B/mammalian target of rapamycin signaling pathway

Yutian Lei, Jinyu Su, Haixia Xu, Qiang Yu, Ming Zhao, Jing Tian
Pages: 447-454
Published online on: 09 May 2018

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Article

Sevoflurane suppresses proliferation by upregulating microRNA-203 in breast cancer cells

Jiaying Liu, Longqiu Yang, Xia Guo, Guangli Jin, Qimin Wang, Dongdong Lv, Junli Liu, Qiu Chen, Qiong Song, Baolin Li
Pages: 455-460
Published online on: 03 May 2018

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Article

Identification of CHCHD2 mutations in patients with Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal dementia in China

Xixi Liu, Bin Jiao, Weiwei Zhang, Tingting Xiao, Lihua Hou, Chuzheng Pan, Beisha Tang, Lu Shen
Pages: 461-466
Published online on: 03 May 2018

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Article

Bioinformatics analysis of key differentially expressed genes in well and poorly differentiated endometrial carcinoma

Yuqin Zang, Mengting Dong, Kai Zhang, Wenyan Tian, Yingmei Wang, Fengxia Xue
Pages: 467-476
Published online on: 04 May 2018

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Article

Knockdown of zinc transporter ZIP8 expression inhibits neuroblastoma progression and metastasis in vitro

Zhengrong Mei, Pengke Yan, Ying Wang, Shaozhi Liu, Fang He
Pages: 477-485
Published online on: 02 May 2018

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Article

Hyperoside protects human kidney‑2 cells against oxidative damage induced by oxalic acid

Yongliang Chen, Lihong Ye, Wangjian Li, Dongzhang Li, Feng Li
Pages: 486-494
Published online on: 02 May 2018

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Article

Effects of obatoclax combined with gemcitabine on the biological activity of pancreatic cancer cells under hypoxic conditions

Xin‑Fang Hou, Shuai Li, Chen Wu, Ke Li, Shu‑Ning Xu, Ju‑Feng Wang
Pages: 495-501
Published online on: 26 April 2018

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Article

miR‑486‑5p is upregulated in osteoarthritis and inhibits chondrocyte proliferation and migration by suppressing SMAD2

Junkai Shi, Kansuo Guo, Shile Su, Jun Li, Chunhui Li
Pages: 502-508
Published online on: 26 April 2018

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Article

Exosomal MALAT1 derived from oxidized low-density lipoprotein-treated endothelial cells promotes M2 macrophage polarization

Chaoyang Huang, Jie Han, Yutao Wu, Shan Li, Qiwen Wang, Wenjuan Lin , Jianhua Zhu
Pages: 509-515
Published online on: 07 May 2018

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Article

LncRNA TP73‑AS1 predicts poor prognosis and promotes cell proliferation in ovarian cancer via cell cycle and apoptosis regulation

Xiuyun Li, Xiaoyan Wang, Li Mao, Shuhong Zhao, Haidong Wei
Pages: 516-522
Published online on: 03 May 2018

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Article

An active component containing pterodontic acid and pterodondiol isolated from Laggera pterodonta inhibits influenza A virus infection through the TLR7/MyD88/TRAF6/NF‑κB signaling pathway

Yutao Wang, Jing Li, Wen Yan, Qiaolian Chen, Zhihong Jiang, Rongping Zhang, Xiping Pan, Xinhua Wang
Pages: 523-531
Published online on: 02 May 2018

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Article

Effects of chronic unpredictable mild stress on ovarian reserve in female rats: Feasibility analysis of a rat model of premature ovarian failure

Xiao‑Yan Fu, Hao‑Hao Chen, Ning Zhang, Ming‑Xing Ding, Ying‑Er Qiu, Xiao‑Ming Pan, Yuan‑Shu Fang, Yi‑Ping Lin, Qun Zheng, Wen‑Qian Wang
Pages: 532-540
Published online on: 08 May 2018

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Interleukin‑1β‑mediated suppression of microRNA‑27a‑3p activity in human cartilage via MAPK and NF‑κB pathways: A potential mechanism of osteoarthritis pathogenesis

Xing Li, Peiheng He, Ziqing Li, Haixing Wang, Minghao Liu, Yinbo Xiao, Dongliang Xu, Yan Kang, Hua Wang
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Increased expression of microRNA-338-3p contributes to production of Dsg3 antibody in pemphigus vulgaris patients

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Vacquinol‑1 induces apoptosis in hepatocellular carcinoma cell

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Dextran‑coated superparamagnetic iron oxide nanoparticles activate the MAPK pathway in human primary monocyte cells

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Intraperitoneal injection of thalidomide alleviates early osteoarthritis development by suppressing vascular endothelial growth factor expression in mice

Jia Lin Song, De Long Li, Hang Fang, Dao Zhang Cai
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Inhibition of granzyme B activity blocks inflammation induced by lipopolysaccharide through regulation of endoplasmic reticulum stress signaling in NK92 cells

Lei Wang, Shaowei Jiang, Ling Xiao, Lin Chen, Yanyan Zhang, Jing Tong
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Helicobacter pylori infection impairs gastric epithelial barrier function via microRNA‑100‑mediated mTOR signaling inhibition

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Downregulation of microRNA‑198 suppresses cell proliferation and invasion in retinoblastoma by directly targeting PTEN Retraction in /10.3892/mmr.2022.12831

Dongdong Wei, Yingbin Miao, Lianxia Yu, Degong Wang, Yingli Wang
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Rs2910164 in microRNA‑146a confers an elevated risk of depression in patients with coronary artery disease by modulating the expression of NOS1

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Quercetin protects against inflammation, MMP‑2 activation and apoptosis induction in rat model of cardiopulmonary resuscitation through modulating Bmi‑1 expression

Dawei Wang, Xiaoqian Lou, Xiao‑Ming Jiang, Chenxi Yang, Xiao‑Liang Liu, Nan Zhang
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Expression analysis of ST3GAL4 transcripts in cervical cancer cells

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Andrographolide affects Th1/Th2/Th17 responses of peripheral blood mononuclear cells from ulcerative colitis patients

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Effects of intravenous anesthetics on the phosphorylation of cAMP response element‑binding protein in hippocampal slices of adult mice

Haiying Gao, Lingyu Zhang, Zhenyi Chen, Shuncui Liu, Qinghong Zhang, Bingxi Zhang
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Hong‑Wei Wang, Peng Sun, Yao Chen, Li‑Ping Jiang, Hui‑Ping Wu, Wen Zhang, Feng Gao
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Competing endogenous RNA regulatory network in papillary thyroid carcinoma

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Candesartan targeting of angiotensin II type 1 receptor demonstrates benefits for hypertension in pregnancy via the NF‑κB signaling pathway

Xudong Zhao, Xietong Wang
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PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
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Lysine‑specific demethylase 2 contributes to the proliferation of small cell lung cancer by regulating the expression of TFPI‑2

Yunfeng Cao, Chunhui Guo, Yanhai Yin, Xin Li, Ling Zhou
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Bioinformatic analyses reveal the key pathways and genes in the CXCR4 mediated mesenchymal subtype of glioblastoma

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Transcriptome sequencing analysis reveals the effect of combinative treatment with low‑intensity pulsed ultrasound and magnesium ions on hFOB1.19 human osteoblast cells

Haiyue Zu, Xueting Yi, Dewei Zhao
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A novel anti‑proliferative pentapeptide (ILYMP) isolated from Cyclina sinensis protein hydrolysate induces apoptosis of DU‑145 prostate cancer cells

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Rosuvastatin relieves myocardial ischemia/reperfusion injury by upregulating PPAR‑γ and UCP2

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Downregulation of microRNA‑449a‑5p promotes esophageal squamous cell carcinoma cell proliferation via cyclin D1 regulation

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RNA‑sequencing analysis of aberrantly expressed long non‑coding RNAs and mRNAs in a mouse model of ventilator‑induced lung injury

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G protein‑coupled estrogen receptor/miR‑148a/human leukocyte antigen‑G signaling pathway mediates cell apoptosis of ovarian endometriosis

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Cyclin‑dependent kinase 10 prevents glioma metastasis via modulation of Snail expression

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MicroRNA‑874 inhibits proliferation and invasion of pancreatic ductal adenocarcinoma cells by directly targeting paired box 6 Retraction in /10.3892/mmr.2022.12873

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Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
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Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
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Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

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Published online on: 10 November 2025

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Ayman A. Althubity
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Published online on: 10 November 2025

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Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

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Article Number: 23
Published online on: 31 October 2025

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Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
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Published online on: 31 October 2025

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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

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Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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