Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
July-2018 Volume 18 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July-2018 Volume 18 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats

  • Authors:
    • Hye Jeong Yang
    • Min Jung Kim
    • Eun Seon Kang
    • Da Sol Kim
    • Sunmin Park
  • View Affiliations / Copyright

    Affiliations: Food Functional Research Division, Korean Food Research Institutes, Wanju, Jeollabuk 55365, Republic of Korea, Department of Food and Nutrition, Obesity/Diabetes Center, Hoseo University, Asan, South Chungcheong 336‑795, Republic of Korea
  • Pages: 1197-1205
    |
    Published online on: May 14, 2018
       https://doi.org/10.3892/mmr.2018.9017
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Red mulberry (Morus alba) fruit is rich in anthocyanins, and mulberry leaves are used by silk worms to make silk protein. We determined that the water and ethanol extract of mulberry fruit and silk amino acids accelerated ethanol degradation and suppressed temporal cognitive dysfunction in acute alcohol administered rats. The mechanism was explored in rats with acute oral administration of silk protein and mulberry fruit extracts. Rats were given 0.3 g of dextrin (control) and water extract (WMB) and ethanol extract of mulberry (EMB), silk protein hydrolysates (SKA), and a commercial product (positive‑control) based on body weight. After 30 min, rats were administered 3 g ethanol/kg body weight and serum ethanol and acetaldehyde levels were measured. After 3 h movements were measured with a video tracking system and at 5 h cognitive function was measured by Y maze test. WMB contain much higher rutin, luteolin and quercetins than EMB. In SKA rats, serum alcohol concentrations slowly increased until 60 min, but were markedly elevated until 120 min. However, WMB rats exhibited rapidly increased serum alcohol levels until 60 min and showed the lowest peak of serum alcohol levels, indicating the highest degradation of alcohol. The patterns of serum acetaldehyde levels were similar to those of serum ethanol levels but WMB was more effective for reducing serum acetaldehyde levels than serum ethanol levels. WMB was most effective for increasing mRNA expression of alcohol dehydrogenase and acetaldehyde dehydrogenase. WMB and SKA decreased lipid peroxides by increasing activities of SOD and GSH‑Px in the liver and they also reduced pro‑inflammatory cytokines such as tumor necrosis factor‑α and interleukin‑6. WMB and SKA exerted better anti‑oxidant effects than the positive‑control. WMB containing higher flavonoids reduced pro‑inflammatory cytokines better than SKA. In conclusions, both WMB and SKA might reduce acute alcohol‑induced hangover and liver and brain damage by lowering serum alcohol and acetaldehyde levels.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Chi YC, Lee SL, Lai CL, Lee YP, Lee SP, Chiang CP and Yin SJ: Ethanol oxidation and the inhibition by drugs in human liver, stomach and small intestine: Quantitative assessment with numerical organ modeling of alcohol dehydrogenase isozymes. Chem Biol Interact. 258:134–141. 2016. View Article : Google Scholar : PubMed/NCBI

2 

French SW: Chronic alcohol binging injures the liver and other organs by reducing NAD+ levels required for sirtuin's deacetylase activity. Exp Mol Pathol. 100:303–306. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Sung CK, Kim SM, Oh CJ, Yang SA, Han BH and Mo EK: Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions. Food Chem Toxicol. 50:2508–2514. 2012. View Article : Google Scholar : PubMed/NCBI

4 

Shi P, Chen B, Chen C, Xu J, Shen Z, Miao X and Yao H: Honey reduces blood alcohol concentration but not affects the level of serum MDA and GSH-Px activity in intoxicated male mice models. BMC Complement Altern Med. 15:2252015. View Article : Google Scholar : PubMed/NCBI

5 

Younossi Z and Henry L: Contribution of alcoholic and nonalcoholic fatty liver disease to the burden of liver-related morbidity and mortality. Gastroenterology. 150:1778–1785. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Enrico P and Diana M: On the accuracy of in vivo ethanol and acetaldehyde monitoring, a key tile in the puzzle of acetaldehyde as a neuroactive agent. Front Behav Neurosci. 11:972017. View Article : Google Scholar : PubMed/NCBI

7 

Song BJ, Akbar M, Jo I, Hardwick JP and Abdelmegeed MA: Translational implications of the alcohol-metabolizing enzymes, including cytochrome P450-2E1, in alcoholic and nonalcoholic liver disease. Adv Pharmacol. 74:303–372. 2015. View Article : Google Scholar : PubMed/NCBI

8 

Polavarapu R, Spitz DR, Sim JE, Follansbee MH, Oberley LW, Rahemtulla A and Nanji AA: Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil. Hepatology. 27:1317–1323. 1998. View Article : Google Scholar : PubMed/NCBI

9 

Lee MH, Kwak JH, Jeon G, Lee JW, Seo JH, Lee HS and Lee JH: Red ginseng relieves the effects of alcohol consumption and hangover symptoms in healthy men: A randomized crossover study. Food Funct. 5:528–534. 2014. View Article : Google Scholar : PubMed/NCBI

10 

Lee HS, Isse T, Kawamoto T, Baik HW, Park JY and Yang M: Effect of Korean pear (Pyruspyrifolia cv. Shingo) juice on hangover severity following alcohol consumption. Food Chem Toxicol. 58:101–106. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Yim DS, Lee KH, Jang IJ, Shin S, Lee YS and Park SC: Effect of aspartate and asparagine on metabolism and central nervous system effect of alcohol in healthy male volunteers. Kor J Pharmacol. 31:261–269. 2009.

12 

Ko BS, Jang JS, Hong SM, Kim DW, Sung SR, Park HR, Lee JE, Jeon WK and Park S: Effect of new remedies mainly comprised of Hovenia dulcis Thunb on alcohol degradation and liver protection in Sprague Dawley male rats. J Korean Soc Food Sci Nutr. 35:828–834. 2006. View Article : Google Scholar

13 

Jiang Z, Chen C, Wang J, Xie W, Wang M, Li X and Zhang X: Purple potato (Solanum tuberosum L.) anthocyanins attenuate alcohol-induced hepatic injury by enhancing antioxidant defense. J Nat Med. 70:45–53. 2016. View Article : Google Scholar : PubMed/NCBI

14 

Hou Z, Qin P and Ren G: Effect of anthocyanin-rich extract from black rice (Oryza sativa L. Japonica) on chronically alcohol-induced liver damage in rats. J Agric Food Chem. 58:3191–3196. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Li YG, Ji DF, Chen S and Hu GY: Protective effects of sericin protein on alcohol-mediated liver damage in mice. Alcohol Alcohol. 43:246–253. 2008. View Article : Google Scholar : PubMed/NCBI

16 

Raghavendra R, Neelagund S, Kuluvar G, Bhanuprakash V and Revanaiah Y: Protective effect of partially purified 35 kDa protein from silk worm (Bombyx mori) fecal matter against carbon tetrachloride induced hepatotoxicity and in vitro anti-viral properties. Pharm Biol. 48:1426–1431. 2010. View Article : Google Scholar : PubMed/NCBI

17 

Andallu B and Varadacharyulu NC: Gluconeogenic substrates and hepatic gluconeogenic enzymes in streptozotocin-diabetic rats: Effect of mulberry (Morus indica L.) leaves. J Med Food. 10:41–48. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Golub HM, Zhou QG, Zucker H, McMullen MR, Kokiko-Cochran ON, Ro EJ, Nagy LE and Suh H: Chronic alcohol exposure is associated with decreased neurogenesis, aberrant integration of newborn neurons, and cognitive dysfunction in female mice. Alcohol Clin Exp Res. 39:1967–1977. 2015. View Article : Google Scholar : PubMed/NCBI

19 

Park S, Kim DS, Kang S and Shin BK: Synergistic topical application of salt-processed Phellodendron amurense and Sanguisorba officinalis Linne alleviates atopic dermatitis symptoms by reducing levels of immunoglobulin E and pro-inflammatory cytokines in NC/Nga mice. Mol Med Rep. 12:7657–7664. 2015. View Article : Google Scholar : PubMed/NCBI

20 

Tripathi T, Abdi M and Alizadeh H: Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 55:3912–3921. 2014. View Article : Google Scholar : PubMed/NCBI

21 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

22 

Fernández-Checa JC: Alcohol-induced liver disease: When fat and oxidative stress meet. Ann Hepatol. 2:69–75. 2003.PubMed/NCBI

23 

Yang HJ, Kim MJ, Kwon DY, Kang ES, Kang S and Park S: Gastroprotective actions of Taraxacum coreanum Nakai water extracts in ethanol-induced rat models of acute and chronic gastritis. J Ethnopharmacol. 208:84–93. 2017. View Article : Google Scholar : PubMed/NCBI

24 

Wall TL, Luczak SE and Hiller-Sturmhöfel S: Biology, genetics, and environment: underlying factors influencing alcohol metabolism. Alcohol Res. 38:59–68. 2016.PubMed/NCBI

25 

Cha JY, Jung HJ, Jeong JJ, Yang HJ, Kim YT and Lee YS: Effects of amino acids on the activities of alcohol metabolizing enzyme alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH). J Life Sci. 19:pp1321–1327. 2009. View Article : Google Scholar

26 

Raman ST, Ganeshan AK, Chen C, Jin C, Li SH, Chen HJ and Gui Z: In vitro and in vivo antioxidant activity of flavonoid extracted from mulberry fruit (Morus alba L.). Pharmacogn Mag. 12:128–133. 2016. View Article : Google Scholar : PubMed/NCBI

27 

Kim JW, Kim TB, Kim HW, Park SW, Kim HP and Sung SH: Hepatoprotective flavonoids in Opuntia ficus-indica fruits by reducing oxidative stress in primary rat hepatocytes. Pharmacogn Mag. 13:472–476. 2017. View Article : Google Scholar : PubMed/NCBI

28 

Valenti L, Riso P, Mazzocchi A, Porrini M, Fargion S and Agostoni C: Dietary anthocyanins as nutritional therapy for nonalcoholic fatty liver disease. Oxid Med Cell Longev. 2013:1454212013. View Article : Google Scholar : PubMed/NCBI

29 

Swift R and Davidson D: Alcohol hangover: Mechanisms and mediators. Alcohol Health Res World. 22:54–60. 1998.PubMed/NCBI

30 

Mitchell MC Jr, Teigen EL and Ramchandani VA: Absorption and peak blood alcohol concentration after drinking beer, wine, or spirits. Alcohol Clin Exp Res. 38:1200–1204. 2014. View Article : Google Scholar : PubMed/NCBI

31 

Ampawong S, Isarangkul D and Aramwit P: Sericin ameliorated dysmorphic mitochondria in high-cholesterol diet/streptozotocin rat by antioxidative property. Exp Biol Med (Maywood). 242:411–421. 2017. View Article : Google Scholar : PubMed/NCBI

32 

Lee SH, Park D, Yang G, Bae DK, Yang YH, Kim TK, Kim D, Kyung J, Yeon S, Koo KC, et al: Silk and silkworm pupa peptides suppress adipogenesis in preadipocytes and fat accumulation in rats fed a high-fat diet. Eur J Nutr. 51:1011–1019. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Okazaki Y, Kakehi S, Xu Y, Tsujimoto K, Sasaki M, Ogawa H and Kato N: Consumption of sericin reduces serum lipids, ameliorates glucose tolerance and elevates serum adiponectin in rats fed a high-fat diet. Biosci Biotechnol Biochem. 74:1534–1538. 2010. View Article : Google Scholar : PubMed/NCBI

34 

Wu KL, Chaikomin R, Doran S, Jones KL, Horowitz M and Rayner CK: Artificially sweetened versus regular mixers increase gastric emptying and alcohol absorption. Am J Med. 119:802–804. 2006. View Article : Google Scholar : PubMed/NCBI

35 

Bustamante J, Karadayian AG, Lores-Arnaiz S and Cutrera RA: Alterations of motor performance and brain cortex mitochondrial function during ethanol hangover. Alcohol. 46:473–479. 2012. View Article : Google Scholar : PubMed/NCBI

36 

Yoo YM, Jung EM, Kang HY, Choi IG, Choi KC and Jeung EB: The sap of Acer okamotoanum decreases serum alcohol levels after acute ethanol ingestion in rats. Int J Mol Med. 28:489–495. 2011.PubMed/NCBI

37 

Asorey LG, Carbone S, Gonzalez BJ and Cutrera RA: Behavioral effects of the combined use of alcohol and energy drinks on alcohol hangover in an experimental mice model. Neurosci Lett. 670:1–7. 2018. View Article : Google Scholar : PubMed/NCBI

38 

Chen Y, Dong H, Thompson DC, Shertzer HG, Nebert DW and Vasiliou V: Glutathione defense mechanism in liver injury: Insights from animal models. Food Chem Toxicol. 60:38–44. 2013. View Article : Google Scholar : PubMed/NCBI

39 

Srikanta AH, Kumar A, Sukhdeo SV, Peddha MS and Govindaswamy V: The antioxidant effect of mulberry and jamun fruit wines by ameliorating oxidative stress in streptozotocin-induced diabetic Wistar rats. Food Funct. 7:4422–4431. 2016. View Article : Google Scholar : PubMed/NCBI

40 

Wu T, Yin J, Zhang G, Long H and Zheng X: Mulberry and cherry anthocyanin consumption prevents oxidative stress and inflammation in diet-induced obese mice. Mol Nutr Food Res. 60:687–694. 2016. View Article : Google Scholar : PubMed/NCBI

41 

Wen DC, Hu XY, Wang YY, Luo JX, Lin W, Jia LY and Gong XY: Effects of aqueous extracts from Panax ginseng and Hippophae rhamnoides on acute alcohol intoxication: An experimental study using mouse model. J Ethnopharmacol. 192:67–73. 2016. View Article : Google Scholar : PubMed/NCBI

42 

Deehan GA Jr, Hauser SR, Wilden JA, Truitt WA and Rodd ZA: Elucidating the biological basis for the reinforcing actions of alcohol in the mesolimbic dopamine system: The role of active metabolites of alcohol. Front Behav Neurosci. 7:1042013. View Article : Google Scholar : PubMed/NCBI

43 

Deehan GA Jr, Engleman EA, Ding ZM, McBride WJ and Rodd ZA: Microinjections of acetaldehyde or salsolinol into the posterior ventral tegmental area increase dopamine release in the nucleus accumbens shell. Alcohol Clin Exp Res. 37:722–729. 2013. View Article : Google Scholar : PubMed/NCBI

44 

Salaspuro M: Acetaldehyde as a common denominator and cumulative carcinogen in digestive tract cancers. Scand J Gastroenterol. 44:912–925. 2009. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yang HJ, Kim MJ, Kang ES, Kim DS and Park S: Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats. Mol Med Rep 18: 1197-1205, 2018.
APA
Yang, H.J., Kim, M.J., Kang, E.S., Kim, D.S., & Park, S. (2018). Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats. Molecular Medicine Reports, 18, 1197-1205. https://doi.org/10.3892/mmr.2018.9017
MLA
Yang, H. J., Kim, M. J., Kang, E. S., Kim, D. S., Park, S."Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats". Molecular Medicine Reports 18.1 (2018): 1197-1205.
Chicago
Yang, H. J., Kim, M. J., Kang, E. S., Kim, D. S., Park, S."Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats". Molecular Medicine Reports 18, no. 1 (2018): 1197-1205. https://doi.org/10.3892/mmr.2018.9017
Copy and paste a formatted citation
x
Spandidos Publications style
Yang HJ, Kim MJ, Kang ES, Kim DS and Park S: Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats. Mol Med Rep 18: 1197-1205, 2018.
APA
Yang, H.J., Kim, M.J., Kang, E.S., Kim, D.S., & Park, S. (2018). Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats. Molecular Medicine Reports, 18, 1197-1205. https://doi.org/10.3892/mmr.2018.9017
MLA
Yang, H. J., Kim, M. J., Kang, E. S., Kim, D. S., Park, S."Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats". Molecular Medicine Reports 18.1 (2018): 1197-1205.
Chicago
Yang, H. J., Kim, M. J., Kang, E. S., Kim, D. S., Park, S."Red mulberry fruit aqueous extract and silk proteins accelerate acute ethanol metabolism and promote the anti‑oxidant enzyme systems in rats". Molecular Medicine Reports 18, no. 1 (2018): 1197-1205. https://doi.org/10.3892/mmr.2018.9017
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team