|
1
|
Coleman MH and Bueno R: Role of adjuvant
chemotherapy in NSCLC (stages I to III). Surg Oncol Clin N Am.
20:757–767. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Pillai RN and Owonikoko TK: Small cell
lung cancer: Therapies and targets. Semin Oncol. 41:133–142. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Arcaro A: Targeted therapies for small
cell lung cancer: Where do we stand? Crit Rev Oncol Hematol.
95:154–164. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Spigel DR, Townley PM, Waterhouse DM, Fang
L, Adiguzel I, Huang JE, Karlin DA, Faoro L, Scappaticci FA and
Socinski MA: Randomized phase II study of bevacizumab in
combination with chemotherapy in previously untreated
extensive-stage small-cell lung cancer: Results from the SALUTE
trial. J Clin Oncol. 29:2215–2222. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hopkins-Donaldson S, Ziegler A, Kurtz S,
Kurtz S, Bigosch C, Kandioler D, Ludwig C, Zangemeister-Wittke U
and Stahel R: Silencing of death receptor and caspase-8 expression
in small cell lung carcinoma cell lines and tumors by DNA
methylation. Cell Death Differ. 10:356–364. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tanaka N, Toyooka S, Soh J, Kubo T,
Yamamoto H, Maki Y, Muraoka T, Shien K, Furukawa M, Ueno T, et al:
Frequent methylation and oncogenic role of microRNA-34b/c in
small-cell lung cancer. Lung Cancer. 76:32–38. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Tsou JA, Hagen JA, Carpenter CL and
Laird-Offringa IA: DNA methylation analysis: A powerful new tool
for lung cancer diagnosis. Oncogene. 21:5450–5461. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Karytinos A, Forneris F, Profumo A,
Ciossani G, Battaglioli E, Binda C and Mattevi A: A novel mammalian
flavin-dependent histone demethylase. J Biol Che. 284:17775–17782.
2009. View Article : Google Scholar
|
|
9
|
Fang R, Barbera AJ, Xu Y, Rutenberg M,
Leonor T, Bi Q, Lan F, Mei P, Yuan GC, Lian C, et al: Human
LSD2/KDM1b/AOF1 regulates gene transcription by modulating
intragenic H3K4me2 methylation. Mol Cell. 39:222–233. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chen L, Vasilatos SN, Qin Y, Oesterreich
S, Davidson NE and Huang Y: Abstract 1385: New insights into the
roles of histone lysine-specific demethylase 2 (LSD2) in breast
cancer. AACR. 77:13852017.
|
|
11
|
Katz TA, Vasilatos SN, Oesterreich S,
Chandran U, Davidson NE and Huang Y: Abstract 1052: Synergy between
inhibition of novel histone demethylase (LSD2) and DNA
methyltransferase (DNMT) and histone deacetylase (HDAC) in
modulating gene expression and inhibiting growth in human breast
cancer cells. AACR. 72:10522012.
|
|
12
|
Yang Y, Yin X, Yang H and Xu Y: Histone
demethylase LSD2 acts as an E3 ubiquitin ligase and inhibits cancer
cell growth through promoting proteasomal degradation of OGT. Mol
Cell. 58:47–59. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Qin H, Chan MW, Liyanarachchi S, Balch C,
Potter D, Souriraj IJ, Cheng AS, Agosto-Perez FJ, Nikonova EV, Yan
PS, et al: An integrative ChIP-chip and gene expression profiling
to model SMAD regulatory modules. BMC Syst Biol. 3:732009.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chen L, Vasilatos SN, Qin Y, Katz TA, Cao
C, Wu H, Tasdemir N, Levine KM, Oesterreich S, Davidson NE and
Huang Y: Functional characterization of lysine-specific demethylase
2 (LSD2/KDM1B) in breast cancer progression. Oncotarget.
8:81737–81753. 2017.PubMed/NCBI
|
|
15
|
Mino K, Nishimura S, Ninomiya S, Tujii H,
Matsumori Y, Tsuchida M, Hosoi M, Koseki K, Wada S, Hasegawa M, et
al: Regulation of tissue factor pathway inhibitor-2 (TFPI-2)
expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).
Biosci Biotechnol Biochem. 78:1010–1017. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Konduri SD, Tasiou A, Chandrasekar N and
Rao JS: Overexpression of tissue factor pathway inhibitor-2
(TFPI-2), decreases the invasiveness of prostate cancer cells in
vitro. Int J Oncol. 18:127–131. 2001.PubMed/NCBI
|
|
17
|
Cruickshanks HA, Vafadar-Isfahani N,
Dunican DS, Lee A, Sproul D, Lund JN, Meehan RR and Tufarelli C:
Expression of a large LINE-1-driven antisense RNA is linked to
epigenetic silencing of the metastasis suppressor gene TFPI-2 in
cancer. Nucleic Acids Res. 41:6857–6869. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Kader F and Ghai M: DNA methylation-based
variation between human populations. Mol Genet Genomics. 292:5–35.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Qu Y, Dang S and Hou P: Gene methylation
in gastric cancer. Clin Chim Acta. 424:53–65. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Karlić R, Chung HR, Lasserre J, Vlahovicek
K and Vingron M: Histone modification levels are predictive for
gene expression. Proc Natl Acad Sci USA. 107:2926–2931. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Heintzman ND, Hon GC, Hawkins RD,
Kheradpour P, Stark A, Harp LF, Ye Z, Lee LK, Stuart RK, Ching CW,
et al: Histone modifications at human enhancers reflect global
cell-type-specific gene expression. Nature. 459:108–112. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Gupta J, Kumar S, Li J, Krishna Murthy
Karuturi R and Tikoo K: Histone H3 lysine 4 monomethylation
(H3K4me1) and H3 lysine 9 monomethylation (H3K9me1): Distribution
and their association in regulating gene expression under
hyperglycaemic/hyperinsulinemic conditions in 3T3 cells. Biochimie.
94:2656–2664. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Katz TA, Vasilatos SN, Harrington E,
Oesterreich S, Davidson NE and Huang Y: Inhibition of histone
demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases
sensitivity to DNMT inhibitor-induced apoptosis in breast cancer
cells. Breast Cancer Res Treat. 146:99–108. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Schulte JH, Lim S, Schramm A, Friedrichs
N, Koster J, Versteeg R, Ora I, Pajtler K, Klein-Hitpass L,
Kuhfittig-Kulle S, et al: Lysine-specific demethylase 1 is strongly
expressed in poorly differentiated neuroblastoma: Implications for
therapy. Cancer Res. 69:2065–2071. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Wu D, Xiong L, Wu S, Jiang M, Lian G and
Wang M: TFPI-2 methylation predicts poor prognosis in non-small
cell lung cancer. Lung Cancer. 76:106–111. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhang Q, Zhang Y, Wang SZ, Wang N, Jiang
WG, Ji YH and Zhang SL: Reduced expression of tissue factor pathway
inhibitor-2 contributes to apoptosis and angiogenesis in cervical
cancer. J Exp Clin Cancer Res. 31:12012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Hu H, Chen X, Wang C, Jiang Y, Li J, Ying
X, Yang Y, Li B, Zhou C, Zhong J, et al: The role of TFPI2
hypermethylation in the detection of gastric and colorectal cancer.
Oncotarget. 8:84054–84065. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Sato N, Parker AR, Fukushima N, Miyagi Y,
Iacobuzio-Donahue CA, Eshleman JR and Goggins M: Epigenetic
inactivation of TFPI-2 as a common mechanism associated with growth
and invasion of pancreatic ductal adenocarcinoma. Oncogene.
24:850–858. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Wang S, Xiao X, Zhou X, Huang T, Du C, Yu
N, Mo Y, Lin L, Zhang J, Ma N, et al: TFPI-2 is a putative tumor
suppressor gene frequently inactivated by promoter hypermethylation
in nasopharyngeal carcinoma. BMC Cancer. 10:6172010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Konduri SD, Srivenugopal KS, Yanamandra N,
Dinh DH, Olivero WC, Gujrati M, Foster DC, Kisiel W, Ali-Osman F,
Kondraganti S, et al: Promoter methylation and silencing of the
tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an
inhibitor of matrix metalloproteinases in human glioma cells.
Oncogene. 22:4509–4516. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Hubé F, Reverdiau P, Iochmann S, Rollin J,
Cherpi-Antar C and Gruel Y: Transcriptional silencing of the TFPI-2
gene by promoter hypermethylation in choriocarcinoma cells. Biol
Chem. 384:1029–1034. 2003. View Article : Google Scholar : PubMed/NCBI
|
