|
1
|
Tobón GJ, Youinou P and Saraux A: The
environment, geo-epidemiology, and autoimmune disease: Rheumatoid
arthritis. J Autoimmun. 35:10–14. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kragstrup TW, Jalilian B, Keller KK, Zhang
X, Laustsen JK, Stengaard-Pedersen K, Hetland ML, Hørslev-Petersen
K, Junker P, Østergaard M, et al: Changes in soluble CD18 in murine
autoimmune arthritis and rheumatoid arthritis reflect disease
establishment and treatment response. PLoS One. 11:e01484862016.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Pan TL, Wang PW, Huang CH, Leu YL, Wu TH,
Wu YR and You J: Herbal formula, Scutellariae radix and Rhei
rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a
rat model. Sci Rep. 5:117342015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chen CY, Chen JX, Li W, Li H and Yang B:
Comparative chemical and statistical analysis of cultivated and
wild Radix Scutellariae. Am J Chin Med. 39:1029–1041. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ikemoto S, Sugimura K, Yoshida N, Yasumoto
R, Wada S, Yamamoto K and Kishimoto T: Antitumor effects of
Scutellariae radix and its components baicalein, baicalin, and
wogonin on bladder cancer cell lines. Urology. 55:951–955. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Li HL, Zhang S, Wang Y, Liang RR, Li J, An
P, Wang ZM, Yang J and Li ZF: Baicalein induces apoptosis via a
mitochondrial-dependent caspase activation pathway in T24 bladder
cancer cells. Mol Med Rep. 7:266–270. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Shieh DE, Liu LT and Lin CC: Antioxidant
and free radical scavenging effects of baicalein, baicalin and
wogonin. Anticancer Res. 20:2861–2865. 2000.PubMed/NCBI
|
|
8
|
Xu J and Zhang Y, Xiao Y, Ma S, Liu Q,
Dang S, Jin M, Shi Y, Wan B and Zhang Y: Inhibition of
12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: A
potential therapeutic role for CNS autoimmune disease. Cell Death
Dis. 4:e5692013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Suk K, Lee H, Kang SS, Cho GJ and Choi WS:
Flavonoid baicalein attenuates activation-induced cell death of
brain microglia. J Pharmacol Exp Ther. 305:638–645. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chen CJ, Raung SL, Liao SL and Chen SY:
Inhibition of inducible nitric oxide synthase expression by
baicalein in endotoxin/cytokine-stimulated microglia. Biochem
Pharmacol. 67:957–965. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zhang Y, Shan L, Hua Y, Wang D, Zeng H,
Liu R, Zhang W and Hu Z: Baicalein selectively induces apoptosis in
activated lymphocytes and ameliorates concanavalin a-induced
hepatitis in mice. PLoS One. 8:e695922013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Krakauer T, Li BQ and Young HA: The
flavonoid baicalin inhibits superantigen-induced inflammatory
cytokines and chemokines. FEBS Lett. 500:52–55. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Li BQ, Fu T, Gong WH, Dunlop N, Kung H,
Yan Y, Kang J and Wang JM: The flavonoid baicalin exhibits
anti-inflammatory activity by binding to chemokines.
Immunopharmacology. 49:295–306. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Park CM, Reid PE, Walker DC and MacPherson
BR: A simple, practical ‘swiss roll’ method of preparing tissues
for paraffin or methacrylate embedding. J Microsc. 145:115–120.
1987. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Xu Y, Hunt NH and Bao S: The role of
granulocyte macrophage-colony-stimulating factor in acute
intestinal inflammation. Cell Res. 18:1220–1229. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Takasuna K, Kasai Y, Kitano Y, Mori K,
Kobayashi R, Hagiwara T, Kakihata K, Hirohashi M, Nomura M, Nagai
E, et al: Protective effects of kampo medicines and baicalin
against intestinal toxicity of a new anticancer camptothecin
derivative, irinotecan hydrochloride (CPT-11), in rats. Jpn J
Cancer Res. 86:978–984. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lin M, Li L, Li L, Pokhrel G, Qi G, Rong R
and Zhu T: The protective effect of baicalin against renal
ischemia-reperfusion injury through inhibition of inflammation and
apoptosis. BMC Complement Altern Med. 14:192014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Baylor NW, Fu T, Yan YD and Ruscetti FW:
Inhibition of human T cell leukemia virus by the plant flavonoid
baicalin (7-glucuronic acid, 5,6-dihydroxyflavone). J Infect Dis.
165:433–437. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chang WH, Chen CH and Lu FJ: Different
effects of baicalein, baicalin and wogonin on mitochondrial
function, glutathione content and cell cycle progression in human
hepatoma cell lines. Planta Med. 68:128–132. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Di Sante G, Tolusso B, Fedele AL, Gremese
E, Alivernini S, Nicolò C, Ria F and Ferraccioli G: Collagen
specific T-cell repertoire and HLA-DR alleles: Biomarkers of active
refractory rheumatoid arthritis. EBioMedicine. 2:2037–2045. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Schultz HS, Guo L, Keller P, Fleetwood AJ,
Sun M, Guo W, Ma C, Hamilton JA, Bjørkdahl O, Berchtold MW and
Panina S: OSCAR-collagen signaling in monocytes plays a
proinflammatory role and may contribute to the pathogenesis of
rheumatoid arthritis. Eur J Immunol. 46:952–963. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Palone F, Vitali R, Cucchiara S,
Pierdomenico M, Negroni A, Aloi M, Nuti F, Felice C, Armuzzi A and
Stronati L: Role of HMGB1 as a suitable biomarker of subclinical
intestinal inflammation and mucosal healing in patients with
inflammatory bowel disease. Inflamm Bowel Dis. 20:1448–1457. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Liongue C, O'Sullivan LA, Trengove MC and
Ward AC: Evolution of JAK-STAT pathway components: Mechanisms and
role in immune system development. PLoS One. 7:e327772012.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Abell K and Watson CJ: The Jak/Stat
pathway: A novel way to regulate PI3K activity. Cell Cycle.
4:897–900. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zoranovic T, Grmai L and Bach EA:
Regulation of proliferation, cell competition, and cellular growth
by the Drosophila JAK-STAT pathway. JAKSTAT.
2:e254082013.PubMed/NCBI
|
|
27
|
Kowshik J, Baba AB, Giri H, Reddy Deepak
G, Dixit M and Nagini S: Astaxanthin inhibits JAK/STAT-3 signaling
to abrogate cell proliferation, invasion and angiogenesis in a
hamster model of oral cancer. PLoS One. 9:e1091142014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Katsuyama T, Comoglio F, Seimiya M, Cabuy
E and Paro R: During Drosophila disc regeneration, JAK/STAT
coordinates cell proliferation with Dilp8-mediated developmental
delay. Proc Natl Acad Sci USA. 112:E2327–E2336. 2015. View Article : Google Scholar : PubMed/NCBI
|
