1
|
Herzig S, Raemy E, Montessuit S, Veuthey
JL, Zamboni N, Westermann B, Kunji ER and Martinou JC:
Identification and functional expression of the mitochondrial
pyruvate carrier. Science. 337:93–96. 2012. View Article : Google Scholar : PubMed/NCBI
|
2
|
Bricker DK, Taylor EB, Schell JC, Orsak T,
Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N,
et al: A mitochondrial pyruvate carrier required for pyruvate
uptake in yeast, Drosophila, and humans. Science. 337:96–100. 2012.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Schell JC, Wisidagama DR, Bensard C, Zhao
H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, et
al: Control of intestinal stem cell function and proliferation by
mitochondrial pyruvate metabolism. Nat Cell Biol. 19:1027–1036.
2017. View
Article : Google Scholar : PubMed/NCBI
|
4
|
Divakaruni AS, Wallace M, Buren C,
Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ,
Bloodgood BL, et al: Inhibition of the mitochondrial pyruvate
carrier protects from excitotoxic neuronal death. J Cell Biol.
216:1091–1105. 2017. View Article : Google Scholar : PubMed/NCBI
|
5
|
Vigueira PA, McCommis KS, Hodges WT,
Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG,
Kletzien RF, Colca JR and Finck BN: The beneficial metabolic
effects of insulin sensitizers are not attenuated by mitochondrial
pyruvate carrier 2 hypomorphism. Exp Physiol. 102:985–999. 2017.
View Article : Google Scholar : PubMed/NCBI
|
6
|
McCommis KS, Hodges WT, Brunt EM,
Nalbantoglu I, McDonald WG, Holley C, Fujiwara H, Schaffer JE,
Colca JR and Finck BN: Targeting the mitochondrial pyruvate carrier
attenuates fibrosis in a mouse model of nonalcoholic
steatohepatitis. Hepatology. 65:1543–1556. 2017. View Article : Google Scholar : PubMed/NCBI
|
7
|
Bender T and Martinou JC: The
mitochondrial pyruvate carrier in health and disease: To carry or
not to carry? Biochim Biophys Acta. 1863:2436–2442. 2016.
View Article : Google Scholar : PubMed/NCBI
|
8
|
De Bock K, Georgiadou M, Schoors S,
Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesquière B,
Cauwenberghs S, Eelen G, et al: Role of PFKFB3-driven glycolysis in
vessel sprouting. Cell. 154:651–663. 2013. View Article : Google Scholar : PubMed/NCBI
|
9
|
Bachetti T and Morbidelli L: Endothelial
cells in culture: A model for studying vascular functions.
Pharmacol Res. 42:9–19. 2000. View Article : Google Scholar : PubMed/NCBI
|
10
|
Patterson JN, Cousteils K, Lou JW, Fox
Manning JE, MacDonald PE and Joseph JW: Mitochondrial metabolism of
pyruvate is essential for regulating glucose-stimulated insulin
secretion. J Biol Chem. 289:13335–13346. 2014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Li Y, Li X, Kan Q, Zhang M, Li X, Xu R,
Wang J, Yu D, Goscinski MA, Wen JG, et al: Mitochondrial pyruvate
carrier function is negatively linked to Warburg phenotype in vitro
and malignant features in esophageal squamous cell carcinomas.
Oncotarget. 8:1058–1073. 2017.PubMed/NCBI
|
12
|
Xu Y, An X, Guo X, Habtetsion TG, Wang Y,
Xu X, Kandala S, Li Q, Li H, Zhang C, et al: Endothelial PFKFB3
plays a critical role in angiogenesis. Arterioscler Thromb Vasc
Biol. 34:1231–1239. 2014. View Article : Google Scholar : PubMed/NCBI
|
13
|
Yu Z, Zhao X, Huang L, Zhang T, Yang F,
Xie L, Song S, Miao P, Zhao L, Sun X, et al: Proviral insertion in
murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase
M2 (PKM2) and promotes glycolysis in cancer cells. J Biol Chem.
288:35406–35416. 2013. View Article : Google Scholar : PubMed/NCBI
|
14
|
Lee YJ, Jeong SY, Karbowski M, Smith CL
and Youle RJ: Roles of the mammalian mitochondrial fission and
fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell.
15:5001–5011. 2004. View Article : Google Scholar : PubMed/NCBI
|
15
|
Hildyard JC, Ammälä C, Dukes ID, Thomson
SA and Halestrap AP: Identification and characterisation of a new
class of highly specific and potent inhibitors of the mitochondrial
pyruvate carrier. Biochim Biophys Acta. 1707:221–230. 2005.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Tang X, Luo YX, Chen HZ and Liu DP:
Mitochondria, endothelial cell function, and vascular diseases.
Front Physiol. 5:1752014. View Article : Google Scholar : PubMed/NCBI
|
17
|
Xiao B, Deng X, Lim GGY, Xie S, Zhou ZD,
Lim KL and Tan EK: Superoxide drives progression of
Parkin/PINK1-dependent mitophagy following translocation of Parkin
to mitochondria. Cell Death Dis. 8:e30972017. View Article : Google Scholar : PubMed/NCBI
|
18
|
Dromparis P and Michelakis ED:
Mitochondria in vascular health and disease. Annu Rev Physiol.
75:95–126. 2013. View Article : Google Scholar : PubMed/NCBI
|
19
|
Kluge MA, Fetterman JL and Vita JA:
Mitochondria and endothelial function. Circ Res. 112:1171–1188.
2013. View Article : Google Scholar : PubMed/NCBI
|
20
|
Wong BW, Marsch E, Treps L, Baes M and
Carmeliet P: Endothelial cell metabolism in health and disease:
Impact of hypoxia. EMBO J. 36:2187–2203. 2017. View Article : Google Scholar : PubMed/NCBI
|
21
|
Tretyakov AV and Farber HW: Endothelial
cell tolerance to hypoxia. Potential role of purine nucleotide
phosphates. J Clin Invest. 95:738–744. 1995. View Article : Google Scholar : PubMed/NCBI
|
22
|
Schofield CJ and Ratcliffe PJ: Oxygen
sensing by HIF hydroxylases. Nat Rev Mol Cell Biol. 5:343–354.
2004. View
Article : Google Scholar : PubMed/NCBI
|
23
|
Jezek P and Plecitá-Hlavatá L:
Mitochondrial reticulum network dynamics in relation to oxidative
stress, redox regulation, and hypoxia. Int J Biochem Cell Biol.
41:1790–1804. 2009. View Article : Google Scholar : PubMed/NCBI
|
24
|
Olichon A, Baricault L, Gas N, Guillou E,
Valette A, Belenguer P and Lenaers G: Loss of OPA1 perturbates the
mitochondrial inner membrane structure and integrity, leading to
cytochrome c release and apoptosis. J Biol Chem. 278:7743–7746.
2003. View Article : Google Scholar : PubMed/NCBI
|
25
|
Yu J, Wu J, Xie P, Maimaitili Y, Wang J,
Xia Z, Gao F, Zhang X and Zheng H: Sevoflurane postconditioning
attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring
mitochondrial morphology. PeerJ. 4:e26592016. View Article : Google Scholar : PubMed/NCBI
|
26
|
Zhao L, Li S, Wang S, Yu N and Liu J: The
effect of mitochondrial calcium uniporter on mitochondrial fission
in hippocampus cells ischemia/reperfusion injury. Biochem Biophys
Res Commun. 461:537–542. 2015. View Article : Google Scholar : PubMed/NCBI
|
27
|
Chitra L and Boopathy R: Adaptability to
hypobaric hypoxia is facilitated through mitochondrial
bioenergetics: An in vivo study. Br J Pharmacol. 169:1035–1047.
2013. View Article : Google Scholar : PubMed/NCBI
|
28
|
Boeckel JN, Derlet A, Glaser SF, Luczak A,
Lucas T, Heumüller AW, Krüger M, Zehendner CM, Kaluza D,
Doddaballapur A, et al: JMJD8 regulates angiogenic sprouting and
cellular metabolism by interacting with pyruvate kinase M2 in
endothelial cells. Arterioscler Thromb Vasc Biol. 36:1425–1433.
2016. View Article : Google Scholar : PubMed/NCBI
|