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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2018 Volume 18 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Cell‑specific histone modifications in atherosclerosis (Review)

Wanlin Jiang, Devendra K. Agrawal, Chandra S. Boosani
Pages: 1215-1224
Published online on: 06 June 2018

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Review Open Access

Computational approaches for predicting key transcription factors in targeted cell reprogramming (Review)

Guillermo‑Issac Guerrero‑Ramirez, Cesar‑Miguel Valdez‑Cordoba, Jose‑Francisco Islas‑Cisneros, Victor Trevino
Pages: 1225-1237
Published online on: 29 May 2018

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Review

Efficacy prediction of targeted therapy for gastric cancer: The current status (Review)

Wanjing Feng, Xiaodong Zhu
Pages: 1238-1246
Published online on: 06 June 2018

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Article

Napsin A is negatively associated with EMT‑mediated EGFR‑TKI resistance in lung cancer cells

Linshui Zhou, Xin Lv, Junchao Yang, Yuanhong Zhu, Zhen Wang, Tingzhen Xu
Pages: 1247-1252
Published online on: 25 May 2018

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Article Open Access

microRNA‑183 is involved in the differentiation and regeneration of Notch signaling‑prohibited hair cells from mouse cochlea

Wei Zhou, Jintao Du, Di Jiang, Xianren Wang, Kaitian Chen, Haocheng Tang, Xuemei Zhang, Hui Cao, Ling Zong, Chang Dong, Hongyan Jiang
Pages: 1253-1262
Published online on: 05 June 2018

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Article Open Access

Identification of genes and signaling pathways associated with the pathogenesis of juvenile spondyloarthritis

Zhe Wang, Yudi Han, Zhaoqing Zhang, Cunfeng Jia, Qiang Zhao, Wei Song, Tao Chen, Yifan Zhang, Xiuhui Wang
Pages: 1263-1270
Published online on: 06 June 2018

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Article Open Access

Differences in the expression profiles of claudin proteins in human gastric carcinoma compared with non‑neoplastic mucosa

Luoluo Yang, Xun Sun, Xiangwei Meng
Pages: 1271-1278
Published online on: 01 June 2018

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Article Open Access

miR‑339‑5p negatively regulates loureirin A‑induced hair follicle stem cell differentiation by targeting DLX5

Xiangjun Li, Yuqiong Wu, Fangfang Xie, Fengxue Zhang, Saixia Zhang, Jianhong Zhou, Dongfeng Chen, Aijun Liu
Pages: 1279-1286
Published online on: 31 May 2018

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Article Open Access

Inflammatory cytokine profile of co‑cultivated primary cells from the endometrium of women with and without endometriosis

Adriana Luckow Invitti, Eduardo Schor, Rafael Martins Parreira, Alexander Kopelman, Gil Kamergorodsky, Giovana Aparecida Gonçalves, Manoel João Batista Castello Girão
Pages: 1287-1296
Published online on: 06 June 2018

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Article Open Access

System analysis of teratozoospermia mRNA profile based on integrated bioinformatics tools

Tiancheng Zhang, Jun Wu, Caihua Liao, Zhong Ni, Jufen Zheng, Fudong Yu
Pages: 1297-1304
Published online on: 31 May 2018

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Article Open Access

CXCL9 promotes prostate cancer progression through inhibition of cytokines from T cells

Shanfeng Tan, Kai Wang, Fuguang Sun, Yang Li, Yisheng Gao
Pages: 1305-1310
Published online on: 11 June 2018

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Article Open Access

Genes associated with inflammation and the cell cycle may serve as biomarkers for the diagnosis and prognosis of acute myocardial infarction in a Chinese population

Jiang Su, Changqing Gao, Rong Wang, Cangsong Xiao, Ming Yang
Pages: 1311-1322
Published online on: 25 May 2018

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Article Open Access

Salvianolic acid B reverses multidrug resistance in nude mice bearing human colon cancer stem cells

Piaoting Guo, Jianchao Wang, Wencang Gao, Xia Liu, Shaofei Wu, Boshun Wan, Lei Xu, Yanhua Li
Pages: 1323-1334
Published online on: 29 May 2018

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Article Open Access

Response of hPDLSCs on 3D printed PCL/PLGA composite scaffolds in vitro

Caixia Peng, Jinxuan Zheng, Dongru Chen, Xueqin Zhang, Lidi Deng, Zhengyuan Chen, Liping Wu
Pages: 1335-1344
Published online on: 25 May 2018

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Article Open Access

Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway

Hao Zhang, Ning Hu
Pages: 1345-1352
Published online on: 01 June 2018

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Article Open Access

Lipid raft‑associated β‑adducin participates in neutrophil migration

Chen Yang, Zhefeng Sui, Tingshuang Xu, Wenai Liu, Xiaoguang Wang, Xianlu Zeng
Pages: 1353-1360
Published online on: 31 May 2018

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Article Open Access

Sipi soup inhibits cancer‑associated fibroblast activation and the inflammatory process by downregulating long non‑coding RNA HIPK1‑AS

Bingxiu Zhou, Yuanyuan Yu, Lixia Yu, Binfu Que, Rui Qiu
Pages: 1361-1368
Published online on: 06 June 2018

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Article Open Access

Fennel main constituent, trans‑anethole treatment against LPS‑induced acute lung injury by regulation of Th17/Treg function

Sichao Zhang, Xi Chen, Ichinkhorloo Devshilt, Qi Yun, Cong Huang, Lijun An, Sosorburam Dorjbat, Xin He
Pages: 1369-1376
Published online on: 07 June 2018

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Article Open Access

Low expression of KCNN3 may affect drug resistance in ovarian cancer

Xia Liu, Luwei Wei, Bingbing Zhao, Xiangxue Cai, Caihua Dong, Fuqiang Yin
Pages: 1377-1386
Published online on: 31 May 2018

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Article Open Access

The roles of the TLR/NF‑κB signaling pathway in the mutual interactions between the lung and the large intestine

Wen Fu, Jing Zhao, Xinglong Liu, Yongxiang Gao, Chuan Zheng
Pages: 1387-1394
Published online on: 31 May 2018

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Article Open Access

miR‑141 inhibits glioma vasculogenic mimicry by controlling EphA2 expression

Guoxiong Li, Min Huang, Yingqian Cai, Yiquan Ke, Yuantao Yang, Xinlin Sun
Pages: 1395-1404
Published online on: 31 May 2018

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Article Open Access

Long non‑coding RNA SENCR alleviates the inhibitory effects of rapamycin on human umbilical vein endothelial cells

Hongtao Sun, Shuiyun Wang, Min Song
Pages: 1405-1414
Published online on: 29 May 2018

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Article Open Access

Screening genes associated with elevated neutrophil‑to‑lymphocyte ratio in chronic heart failure

Guoxing Wan, Lihua Ji, Wenbin Xia, Lan Cheng, Yonggang Zhang
Pages: 1415-1422
Published online on: 05 June 2018

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Article Open Access

A novel APC mutation identified in a large Chinese family with familial adenomatous polyposis and a brief literature review

Minghui Pang, Yijun Liu, Xiaolin Hou, Jialiang Yang, Xuelai He, Nengyi Hou, Peixi Liu, Luo Liang, Junwen Fu, Kang Wang, Zimeng Ye, Bo Gong
Pages: 1423-1432
Published online on: 05 June 2018

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Article Open Access

Curcumin suppresses cardiac fibroblasts activities by regulating the proliferation and cell cycle via the inhibition of the p38 MAPK/ERK signaling pathway

Guanhua Fang, Shaoqin Chen, Qiuyu Huang, Liangwan Chen, Dongshan Liao
Pages: 1433-1438
Published online on: 01 June 2018

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Article Open Access

Protective effect of crocin on ultraviolet B‑induced dermal fibroblast photoaging

Mingwu Deng, Dong Li, Yichen Zhang, Guangdong Zhou, Wei Liu, Yilin Cao, Wenjie Zhang
Pages: 1439-1446
Published online on: 11 June 2018

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Article Open Access

Grape seed proanthocyanidins protect against streptozotocin‑induced diabetic nephropathy by attenuating endoplasmic reticulum stress‑induced apoptosis

Zhaoli Gao, Guangyi Liu, Zhao Hu, Weiwei Shi, Binbin Chen, Peimei Zou, Xianhua Li
Pages: 1447-1454
Published online on: 06 June 2018

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Article Open Access

Physical exercise promotes proliferation and differentiation of endogenous neural stem cells via ERK in rats with cerebral infarction

Wei Liu, Wen Wu, Guangyong Lin, Jian Cheng, Yanyan Zeng, Yu Shi
Pages: 1455-1464
Published online on: 07 June 2018

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Article Open Access

Fibrinogen‑like‑protein 1 promotes the invasion and metastasis of gastric cancer and is associated with poor prognosis

Yang Zhang, Hui‑Xia Qiao, Yong‑Tao Zhou, Liang Hong, Ju‑Hui Chen
Pages: 1465-1472
Published online on: 29 May 2018

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Article Open Access

A three‑lncRNA signature for prognosis prediction of acute myeloid leukemia in patients

Fangce Wang, Xiaoxue Tian, Jie Zhou, Guangming Wang, Wenlei Yu, Zheng Li, Zhuoyi Fan, Wenjun Zhang, Aibin Liang
Pages: 1473-1484
Published online on: 06 June 2018

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Article Open Access

Autophagy protects bone marrow mesenchymal stem cells from palmitate‑induced apoptosis through the ROS‑JNK/p38 MAPK signaling pathways

Yongyi Liu, Ning Wang, Shaokun Zhang, Qingwei Liang
Pages: 1485-1494
Published online on: 30 May 2018

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Article Open Access

Alterations in β‑catenin/E‑cadherin complex formation during the mechanotransduction of Saos‑2 osteoblastic cells

Fei‑Fei Li, Bo Zhang, Ji‑Hong Cui, Fu‑Lin Chen, Yin Ding, Xue Feng
Pages: 1495-1503
Published online on: 07 June 2018

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Article Open Access

Comprehensive evaluation of differential lncRNA and gene expression in patients with intervertebral disc degeneration

Zhigang Qu, Zhe Quan, Qi Zhang, Zhenyu Wang, Qingxu Song, Xinming Zhuang, Changfeng Fu, Feng Xu, Yadong Liu, Yuanyi Wang, Zheng Wang, Yi Liu
Pages: 1504-1512
Published online on: 05 June 2018

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Article Open Access

Identification and functional analysis of differentially expressed genes associated with cerebral ischemia/reperfusion injury through bioinformatics methods

Xiaoli Shao, Wangxiao Bao, Xiaoqin Hong, Huihua Jiang, Zhi Yu
Pages: 1513-1523
Published online on: 06 June 2018

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Article Open Access

miR‑23a downregulation modulates the inflammatory response by targeting ATG12‑mediated autophagy

Xiang Si, Daiyin Cao, Juan Chen, Yao Nie, Zhiyi Jiang, Min‑Ying Chen, Jian‑Feng Wu, Xiang‑Dong Guan
Pages: 1524-1530
Published online on: 29 May 2018

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Article Open Access

A novel method to detect the Mexican founder mutation BRCA1 ex9‑12del associated with breast and ovarian cancer using quantitative polymerase chain reaction and TaqMan® probes

Denisse Aideé Martínez‑Treviño, Rafael Baltazar Reyes León‑Cachón, Cynthia Villarreal‑Garza, Dione Aguilar Y Méndez, Elisa Aguilar‑Martínez, Hugo Alberto Barrera‑Saldaña
Pages: 1531-1537
Published online on: 06 June 2018

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Article Open Access

Identification of candidate biomarkers and pathways associated with SCLC by bioinformatics analysis

Pushuai Wen, Tungamirai Chidanguro, Zhuo Shi, Huanyu Gu, Nan Wang, Tongmei Wang, Yuhong Li, Jing Gao
Pages: 1538-1550
Published online on: 29 May 2018

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Article Open Access

Proteomic profiling for plasma biomarkers of tuberculosis progression

Qiuyue Liu, Liping Pan, Fen Han, Baojian Luo, Hongyan Jia, Aiying Xing, Qi Li, Zongde Zhang
Pages: 1551-1559
Published online on: 05 June 2018

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Article Open Access

Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes subjected to myocardial ischemia‑reperfusion injury via upregulation of the PI3K/Akt pathway

Zhengwen Zhou, Yue Zhang, Luning Lin, Jianmei Zhou
Pages: 1560-1570
Published online on: 31 May 2018

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Article Open Access

Overexpression of retinoblastoma‑binding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3‑kinase/protein kinase B pathway suppression

Xiaoxi Jin, Rui Jiang, Yongsheng Xiang, Zhen Fan, Zhiwei Wu, Bo Yang, Lujun Yang, Shanshan Wei, Yan Yang
Pages: 1571-1581
Published online on: 11 June 2018

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Article Open Access

Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway Corrigendum in /10.3892/mmr.2023.12952

Lin Xu, Xuejun Jiang, Fang Wei, Hongling Zhu
Pages: 1582-1590
Published online on: 29 May 2018

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Article Open Access

miR‑23b inhibits proliferation of SMMC‑7721 cells by directly targeting IL‑11

Tianpeng Jiang, Zhi Huang, Shuai Zhang, Weijie Zou, Lei Xiang, Xiaowen Wu, Yaping Shen, Weixin Liu, Zhu Zeng, Ansu Zhao, Shi Zhou, Qingfan Zeng
Pages: 1591-1599
Published online on: 11 June 2018

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Article Open Access

Induction of apoptosis by Bigelovii A through inhibition of NF‑κB activity

Fuqin Guan, Yu Shan, Qizhi Wang, Ming Wang, Yu Chen, Min Yin, Fei Liu, Youyi Zhao, Jianhua Zhang, Xu Feng
Pages: 1600-1608
Published online on: 30 May 2018

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Article Open Access

SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF‑κB pathway in mouse kupffer cells

Bailin Niu, Kun He, Peizhi Li, Jianping Gong, Xiwen Zhu, Shangmin Ye, Zhibing Ou, Guosheng Ren
Pages: 1609-1615
Published online on: 29 May 2018

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Article Open Access

Long noncoding RNA AFAP1‑AS1 enhances cell proliferation and invasion in osteosarcoma through regulating miR‑4695‑5p/TCF4‑β‑catenin signaling

Rongrui Li, Shichen Liu, Yao Li, Qingxi Tang, Yunchuan Xie, Raosheng Zhai
Pages: 1616-1622
Published online on: 05 June 2018

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Article Open Access

Molecular analysis of Cypriot families with aniridia reveals a novel PAX6 mutation

Andreas Syrimis, Nayia Nicolaou, Angelos Alexandrou, Ioannis Papaevripidou, Michael Nicolaou, Eleni Loukianou, Carolina Sismani, Stavros Malas, Violetta Christophidou‑Anastasiadou, George A. Tanteles
Pages: 1623-1627
Published online on: 05 June 2018

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Article Open Access

Downregulation of miR‑637 promotes proliferation and metastasis by targeting Smad3 in keloids Corrigendum in /10.3892/mmr.2023.13083

Ye Zhang, Bingyu Guo, Qiang Hui, Wei Li, Peng Chang, Kai Tao
Pages: 1628-1636
Published online on: 29 May 2018

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Article Open Access

Pioglitazone restores the homocysteine‑impaired function of endothelial progenitor cells via the inhibition of the protein kinase C/NADPH oxidase pathway

Junhui Zhu, Yanbo Zhao, Lu Yu, Meihui Wang, Qinfeng Li, Shengjie Xu
Pages: 1637-1643
Published online on: 11 June 2018

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Article

CXCR7 silencing inhibits the migration and invasion of human tumor endothelial cells derived from hepatocellular carcinoma by suppressing STAT3

Ye Wu, Lei Tian, Yongle Xu, Minhong Zhang, Shengqing Xiang, Jianguo Zhao, Zhenxia Wang
Pages: 1644-1650
Published online on: 31 May 2018

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Article

Obovatol inhibits the growth and aggressiveness of tongue squamous cell carcinoma through regulation of the EGF‑mediated JAK‑STAT signaling pathway

Mingli Duan, Xiaoming Du, Gang Ren, Yongdong Zhang, Yu Zheng, Shuping Sun, Jun Zhang
Pages: 1651-1659
Published online on: 25 May 2018

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Article

Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts

Yiqun Sun, Haiyang Jiang, Ming Gu, Xinyu Zheng
Pages: 1660-1665
Published online on: 30 May 2018

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Article

miRNA‑195 suppresses cell proliferation of ovarian cancer cell by regulating VEGFR2 and AKT signaling pathways

Jun Chen
Pages: 1666-1673
Published online on: 29 May 2018

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Article

miR‑205 targets YAP1 and inhibits proliferation and invasion in thyroid cancer cells

Dewei Li, Qiang Wang, Ning Li, Shuilong Zhang
Pages: 1674-1681
Published online on: 25 May 2018

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Article

Bushen recipe and its disassembled prescriptions inhibit inflammation of liver injury associated with Concanavalin A through Toll‑like receptor 3/9 signaling pathway

Hongming Nie, Zhaohe Mei, Rong Wang, Binbin Zhao, Yueqiu Gao, Jianjie Chen, Lingtai Wang
Pages: 1682-1691
Published online on: 29 May 2018

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Article

Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkin‑mediated mitophagy by suppressing AMPK/Skp2 pathways Retraction in /10.3892/mmr.2024.13315

Lili He, Kebo Gu
Pages: 1692-1703
Published online on: 29 May 2018

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Article

Increased B cell activating factor is associated with B cell class switching in patients with tuberculous pleural effusion

Xin Wang, Kui‑Di Liang, Jun‑Ai Zhang, Gan‑Bin Liu, Zhi Chen, Chen Chen, Ze‑Gang Zhuang, Yu‑Qing Liu, Hou‑Long Luo, Rui Xi Li, Bi‑Ying Zheng, Jun‑Fa Xu
Pages: 1704-1709
Published online on: 25 May 2018

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Article

Hypoxia induces lactate secretion and glycolytic efflux by downregulating mitochondrial pyruvate carrier levels in human umbilical vein endothelial cells

Dong Wang, Qingjie Wang, Gaoliang Yan, Yong Qiao, Boqian Zhu, Bo Liu, Chengchun Tang
Pages: 1710-1717
Published online on: 29 May 2018

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Article

Reduction in activating transcription factor 4 promotes carbon tetrachloride and lipopolysaccharide/D‑galactosamine‑mediated liver injury in mice

Xiaofang Zhao, Hong Zhou, Ying Cheng, Wenjing Yu, Guosong Luo, Chunyan Duan, Fuli Yao, Bin Xiao, Chunhong Feng, Xianming Xia, Mei Wei, Yong Wang, Jing Li, Rongyang Dai
Pages: 1718-1725
Published online on: 29 May 2018

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Article

Association between age‑related hearing loss and cognitive decline in C57BL/6J mice

Yang Dong, Chun‑Rong Guo, Dan Chen, Sheng‑Min Chen, Yinting Peng, Haiyan Song, Jian‑Rong Shi
Pages: 1726-1732
Published online on: 01 June 2018

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Article

Epithelial‑mesenchymal transition was identified as a potential marker for breast cancer aggressiveness using reverse transcription‑quantitative polymerase chain reaction

Ulrich Andergassen, Kristina Schlenk, Udo Jeschke, Harald Sommer, Alexandra Kölbl
Pages: 1733-1739
Published online on: 29 May 2018

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Article

Effects of microRNA‑210 on the diagnosis and treatment of prostate cancer

Yuejun Qu, Wenqiang Huang
Pages: 1740-1744
Published online on: 31 May 2018

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Article

Upregulation of miR‑122 is associated with cardiomyocyte apoptosis in atrial fibrillation

Xiangqun Zhang, Wenli Jing
Pages: 1745-1751
Published online on: 04 June 2018

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Article

Protective effects of scoparone against ischemia‑reperfusion‑induced myocardial injury

Chunfu Wan, Yueyue Wei, Jianguo Ma, Xiaoyong Geng
Pages: 1752-1760
Published online on: 04 June 2018

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Case Report

Novel HSPG2 mutations causing Schwartz‑Jampel syndrome type 1 in a Chinese family: A case report

Wenjin Yan, Jin Dai, Dongquan Shi, Xingquan Xu, Xiao Han, Zhihong Xu, Dongyang Chen, Huajiang Teng, Qing Jiang
Pages: 1761-1765
Published online on: 06 June 2018

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Article

Integrated computational biology analysis to evaluate target genes for chronic myelogenous leukemia

Yu Zheng, Yu‑Ping Wang, Hongbao Cao, Qiusheng Chen, Xi Zhang
Pages: 1766-1772
Published online on: 05 June 2018

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Article

Organ‑specific expression of the divalent ion channel proteins NCKX3, TRPV2, CTR1, ATP7A, IREG1 and HEPH in various canine organs

Changhwan Ahn, Jong‑Sam Choi, Eui‑Bae Jeung
Pages: 1773-1781
Published online on: 07 June 2018

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Article

TROP2 promotes cell proliferation and migration in osteosarcoma through PI3K/AKT signaling

Qing‑Zhi Gu, Abulimiti Nijiati, Xing Gao, Kai‑Liang Tao, Cheng‑Duo Li, Xue‑Peng Fan, Zheng Tian
Pages: 1782-1788
Published online on: 29 May 2018

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Article

Glucagon‑like peptide‑1 protects mouse podocytes against high glucose‑induced apoptosis, and suppresses reactive oxygen species production and proinflammatory cytokine secretion, through sirtuin 1 activation in vitro

Jian‑Xia Shi, Qin Huang
Pages: 1789-1797
Published online on: 29 May 2018

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Article

CXCL8 and CXCL11 chemokine secretion in dermal fibroblasts is differentially modulated by vanadium pentoxide

P. Fallahi, R. Foddis, G. Elia, F. Ragusa, A. Patrizio, S. Benvenga, A. Cristaudo, A. Antonelli, S. M. Ferrari
Pages: 1798-1803
Published online on: 01 June 2018

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Article

MicroRNA‑539 inhibits cell proliferation, colony formation and invasion in pancreatic ductal adenocarcinoma by directly targeting IGF‑1R

Yongquan Lin, Lihua Rong, Jingrong Zhao, Ronghui Lin, Shuhua Li
Pages: 1804-1811
Published online on: 31 May 2018

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Article

MicroRNA‑199b promotes cell proliferation and invasion in Wilms' tumour by directly targeting Runt‑related transcription factor 3

Huizhen Zhao, Hailing Zhao, Yongna Zhang, Yuxi Zhou
Pages: 1812-1819
Published online on: 29 May 2018

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Article

MG‑132 reverses multidrug resistance by activating the JNK signaling pathway in FaDu/T cells

Juke Ma, Zhenghua Lv, Xiuxiu Liu, Xianfang Liu, Wei Xu
Pages: 1820-1825
Published online on: 06 June 2018

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Article

microRNA‑574 inhibits cell proliferation and invasion in glioblastoma multiforme by directly targeting zinc finger E‑box‑binding homeobox 1 Retraction in /10.3892/mmr.2022.12884

Youyan Mao, Fangmeng Wei, Chenghong Wei, Chengjun Wei
Pages: 1826-1834
Published online on: 31 May 2018

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Article

Synergistic apoptotic effects of silibinin in enhancing paclitaxel toxicity in human gastric cancer cell lines

Yuanxin Zhang, Yakun Ge, Xie Ping, Ming Yu, Dawei Lou, Wei Shi
Pages: 1835-1841
Published online on: 05 June 2018

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Article

B7‑H1‑mediated immunosuppressive properties in human mesenchymal stem cells are mediated by STAT‑1 and not PI3K/Akt signaling

In Keun Jang, Hyun Joo Jung, O Kyu Noh, Doo‑Hoon Lee, Kwang Chul Lee, Jun Eun Park
Pages: 1842-1848
Published online on: 30 May 2018

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Article

Effects of strontium ranelate on wear particle‑induced aseptic loosening in female ovariectomized mice

Tianxiang Geng, Xi Chen, Mengxue Zheng, Haochen Yu, Shuai Zhang, Shouxuan Sun, Haohui Guo, Qunhua Jin
Pages: 1849-1857
Published online on: 05 June 2018

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Article

Protective effect of Letinous edodes foot peptides against ethanol‑induced liver injury in L02 cells

Lin Ma, Chun‑Yan Huo, Xiao‑Yu Zhang, Chen‑Qiang Qin, Di‑Feng Ren, Jun Lu
Pages: 1858-1866
Published online on: 29 May 2018

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Article

Oxidative stress modulates the expression of toll‑like receptor 3 during respiratory syncytial virus infection in human lung epithelial A549 cells

Min‑Min Wang, Min Lu, Chuan‑Long Zhang, Xuan Wu, Jing‑Xian Chen, Wei‑Wei Lv, Tao Sun, Huan Qiu, Sheng‑Hai Huang
Pages: 1867-1877
Published online on: 29 May 2018

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Article

MicroRNA‑655 inhibits cell proliferation and invasion in epithelial ovarian cancer by directly targeting vascular endothelial growth factor Retraction in /10.3892/mmr.2022.12860

Ziling Zhao, Shuna Yang, Yan Cheng, Xiuhua Zhao
Pages: 1878-1884
Published online on: 29 May 2018

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Article

The effect of Mg‑2Zn‑0.5Nd alloy on the mTOR signalling pathway in L6 cells

Wei Lu, Lei Guo, Tianlong Jiang, Shenghui Ni, Yuyan Zhao
Pages: 1885-1891
Published online on: 30 May 2018

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Correction Open Access

[Corrigendum] Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice

Bing He, Xiaoou Li, Tuo Hu, Wenjing Lian, Mingxia Zhang
Pages: 1892-1892
Published online on: 01 June 2018

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Correction Open Access

[Corrigendum] microRNA‑181a‑5p functions as an oncogene in renal cell carcinoma

Yulin Lai, Liwen Zhao, Jia Hu, Jing Quan, Peijie Chen, Jinling Xu, Xin Guan, Yongqing Lai, Liangchao Ni
Pages: 1893-1893
Published online on: 01 June 2018

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Article Open Access

Tanshinone IIA improves hypoxic ischemic encephalopathy through TLR‑4‑mediated NF‑κB signal pathway Retraction in /10.3892/mmr.2025.13428

Chengzhi Fang, Lili Xie, Chunmei Liu, Chunhua Fu, Wei Ye, Hong Liu, Binghong Zhang
Pages: 1899-1908
Published online on: 26 June 2018

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Article Open Access

MicroRNA expression profiles identify biomarkers for predicting the response to chemoradiotherapy in rectal cancer

Binbin Du, Xiaoying Wang, Dewang Wu, Tao Wang, Xiongfei Yang, Jiankai Wang, Xinlong Shi, Lingjuan Chen, Weisheng Zhang
Pages: 1909-1916
Published online on: 25 June 2018

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Article Open Access

Regulatory effects of microRNA‑184 on osteosarcoma via the Wnt/β‑catenin signaling pathway

Zhenguang Du, Fusheng Li, Liangliang Wang, Hai Huang, Shaonian Xu
Pages: 1917-1924
Published online on: 18 June 2018

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Article Open Access

Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats

Dandan Song, Xuelei Liu, Yugang Diao, Yingjie Sun, Guangjie Gao, Tiezheng Zhang, Keyan Chen, Ling Pei
Pages: 1925-1938
Published online on: 20 June 2018

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Article Open Access

Effect of survivin downregulation by simvastatin on the growth and invasion of salivary adenoid cystic carcinoma

Wen‑Yan Cai, Ying Zhuang, Fei Yan, Ting Li, Wen‑Ting Song, Jin‑Hu Sun
Pages: 1939-1946
Published online on: 22 June 2018

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Article Open Access

HBx gene transfection affects the cycle of primary renal tubular epithelial cells through regulating cyclin expression

Wenlun Han, Meiliang Luo, Mengying He, Yunyun Zhu, Yu Zhong, Huideng Ding, Gang Hu, Liansheng Liu, Qin Chen, Ying Lu
Pages: 1947-1954
Published online on: 20 June 2018

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Article Open Access

Weighted gene co‑expression network analysis in identification of key genes and networks for ischemic‑reperfusion remodeling myocardium

Nan Guo, Nan Zhang, Liqiu Yan, Zheng Lian, Jiawang Wang, Fengfeng Lv, Yunfei Wang, Xufen Cao
Pages: 1955-1962
Published online on: 14 June 2018

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Article Open Access

Detection of dysregulated competing endogenous RNA modules associated with clear cell kidney carcinoma

Hong Wang, Dahua Xu, Huiying Huang, Ying Cui, Chunhua Li, Chunrui Zhang, Shengnan Guo, Lining Zhang, Xiaomu Xu, Jiankai Xu, Jianping Lu, Liqiang Wang, Kongning Li
Pages: 1963-1972
Published online on: 19 June 2018

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Article Open Access

Interaction with adipocytes induces lung adenocarcinoma A549 cell migration and tumor growth

Fan-Fan Li, Hang Zhang, Jing-Jing Li, Ya-Nan Cao, Xiang Dong, Cong Gao
Pages: 1973-1980
Published online on: 26 June 2018

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Article Open Access

Antioxidants retard the ageing of mouse oocytes

Yexing Xian, Lifeng Liang, Shutao Qi, Yingjun Xie, Bing Song, Shuming Ouyang, Yuhuan Xie, Xiaofang Sun, Weihua Wang
Pages: 1981-1986
Published online on: 14 June 2018

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Article Open Access

Protective effect of KLF15 on vascular endothelial dysfunction induced by TNF‑α

Bing Liu, Lili Xu, Xinming Yu, Wei Li, Xiaozhi Sun, Shun Xiao, Mingjin Guo, Haofu Wang
Pages: 1987-1994
Published online on: 20 June 2018

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Article Open Access

Spleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome‑mediated IL‑1β secretion via c‑Jun N‑terminal kinase activation and cell apoptosis during diabetic nephropathy

Yingchun Qiao, Xixi Tian, Li Men, Shengyu Li, Yufeng Chen, Meiting Xue, Yahui Hu, Pengfei Zhou, Guangfeng Long, Yue Shi, Ruiqing Liu, Yunde Liu, Zhi Qi, Yujie Cui, Yanna Shen
Pages: 1995-2008
Published online on: 14 June 2018

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Article Open Access

Differentiation of umbilical cord mesenchymal stem cells into hepatocytes in comparison with bone marrow mesenchymal stem cells

Ya‑Bin Yu, Yan Song, Ya Chen, Feng Zhang, Fu‑Zhen Qi
Pages: 2009-2016
Published online on: 18 June 2018

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Article Open Access

Application of 460 nm visible light for the elimination of Candida albicans in vitro and in vivo

Chuan Wang, Zhiyin Yang, Yinbo Peng, Yuanyuan Guo, Min Yao, Jiying Dong
Pages: 2017-2026
Published online on: 20 June 2018

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Article Open Access

Whole‑exome sequencing analysis of products of conception identifies novel mutations associated with missed abortion

Meng Fu, Sha Mu, Chunyan Wen, Shufang Jiang, Lin Li, Yuanguang Meng, Hongmei Peng
Pages: 2027-2032
Published online on: 21 June 2018

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Article Open Access

Effects of isomaltulose on insulin resistance and metabolites in patients with non‑alcoholic fatty liver disease: A metabolomic analysis

Takumi Kawaguchi, Dan Nakano, Tetsuharu Oriishi, Takuji Torimura
Pages: 2033-2042
Published online on: 26 June 2018

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Article Open Access

YC‑1 reduces inflammatory responses by inhibiting nuclear factor‑κB translocation in mice subjected to transient focal cerebral ischemia

Wei‑Ting Lee, Shih‑Huang Tai, Yu‑Wen Lin, Tian‑Shung Wu, E‑Jian Lee
Pages: 2043-2051
Published online on: 15 June 2018

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Article Open Access

Expression of vitamin D receptor in bronchial asthma and its bioinformatics prediction

Lishen Shan, Xinyuan Kang, Fen Liu, Xuxu Cai, Xiaohua Han, Yunxiao Shang
Pages: 2052-2060
Published online on: 13 June 2018

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Article Open Access

TIMP‑3 suppresses the proliferation and migration of SMCs from the aortic neck of atherosclerotic AAA in rabbits, via decreased MMP‑2 and MMP‑9 activity, and reduced TNF‑α expression

Huan Zhai, Xun Qi, Zixuan Li, Wei Zhang, Chenguang Li, Lu Ji, Ke Xu, Hongshan Zhong
Pages: 2061-2067
Published online on: 26 June 2018

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Article Open Access

Antitumor effects of Xi Huang pills on MDA‑MB‑231 cells in vitro and in vivo

Wenxian Zheng, Shuyan Han, Shantong Jiang, Xiran He, Xiaohong Li, Huirong Ding, Minhua Cao, Pingping Li
Pages: 2068-2078
Published online on: 21 June 2018

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Label‑free quantitative proteomics and bioinformatics analyses of alcoholic liver disease in a chronic and binge mouse model

Yu Zhang, Cheng Zhan, Genwen Chen, Jianyong Sun
Pages: 2079-2087
Published online on: 26 June 2018

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Article Open Access

Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice

Lishen Shan, Xinyuan Kang, Fen Liu, Xuxu Cai, Xiaohua Han, Yunxiao Shang
Pages: 2088-2096
Published online on: 18 June 2018

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Article Open Access

Characteristics and multi‑lineage differentiation of bone marrow mesenchymal stem cells derived from the Tibetan mastiff

Shuang Zhang, Chenqiong Zhao, Shi Liu, Yufeng Wang, Yuhua Zhao, Weijun Guan, Zhiqiang Zhu
Pages: 2097-2109
Published online on: 15 June 2018

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C5a aggravates dysfunction of the articular cartilage and synovial fluid in rats with knee joint immobilization

Wei Lu, Lin Wang, Jing Yao, Chunxin Wo, Yu Chen
Pages: 2110-2116
Published online on: 22 June 2018

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Article Open Access

Amplification of bacterial genomic DNA from all ascitic fluids with a highly sensitive polymerase chain reaction

Hirayuki Enomoto, Shin‑Ichi Inoue, Akio Matsuhisa, Yoshinori Iwata, Nobuhiro Aizawa, Yoshiyuki Sakai, Ryo Takata, Naoto Ikeda, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Yuho Miyamoto, Noriko Ishii, Yukihisa Yuri, Akio Ishii, Tomoyuki Takashima, Hiroki Nishikawa, Hiroko Iijima, Shuhei Nishiguchi
Pages: 2117-2123
Published online on: 14 June 2018

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Article Open Access

Inhibition of autophagy enhanced cobalt chloride‑induced apoptosis in rat alveolar type II epithelial cells

Yan Yu, Wanting Li, Liqin Ren, Chunyan Yang, Dongze Li, Xin Han, Yeying Sun, Changjun Lv, Fang Han
Pages: 2124-2132
Published online on: 22 June 2018

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Article Open Access

Effect of electric stimulation on human chondrocytes and mesenchymal stem cells under normoxia and hypoxia

Bettina Hiemer, Martin Krogull, Thomas Bender, Josefin Ziebart, Simone Krueger, Rainer Bader, Anika Jonitz‑Heincke
Pages: 2133-2141
Published online on: 15 June 2018

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N‑terminal truncated peroxisome proliferator‑activated receptor‑γ coactivator‑1α alleviates phenylephrine‑induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes

Zuheng Liu, Jinghai Hua, Wanqiang Cai, Qiong Zhan, Wenyan Lai, Qingchun Zeng, Hao Ren, Dingli Xu
Pages: 2142-2152
Published online on: 14 June 2018

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Identification of differentially expressed genes associated with asthma in children based on the bioanalysis of the regulatory network

Chunyan Wang, Hengtao Li, Lanfang Cao, Genzai Wang
Pages: 2153-2163
Published online on: 22 June 2018

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Article Open Access

Identification of a noncoding RNA‑mediated gene pair‑based regulatory module in Alzheimer's disease

Lin Yu, Shi Qian, Sun Wei
Pages: 2164-2170
Published online on: 19 June 2018

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Article Open Access

Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide‑induced intestinal injury

Ying Xiong, Kai‑Xue Li, Hong Wei, Lu Jiao, Shao‑Yong Yu, Li Zeng
Pages: 2171-2181
Published online on: 14 June 2018

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Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer

Yu Jiang, Gang Liu, Li Zhang, Sheng Cheng, Chun Luo, Yang Liao, Shuliang Guo
Pages: 2182-2190
Published online on: 14 June 2018

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Next‑generation sequencing‑based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her‑2 and TP53 mutations in patients with non‑small cell lung cancer

Changwen Jing, Xuhua Mao, Zhuo Wang, Kejing Sun, Rong Ma, Jianzhong Wu, Haixia Cao
Pages: 2191-2197
Published online on: 22 June 2018

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Article Open Access

Recombinant club cell protein 16 (CC16) ameliorates cigarette smoke‑induced lung inflammation in a murine disease model of COPD

Min Pang, Hong‑Yan Liu, Ting Li, Dan Wang, Xiao‑Yun Hu, Xin‑Ri Zhang, Bao‑Feng Yu, Rui Guo, Hai‑Long Wang
Pages: 2198-2206
Published online on: 25 June 2018

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Article

Inhibitory effects of TGP on KGF‑induced hyperproliferation of HaCaT cells via suppression of the p38 MAPK/NF‑κB p65 pathway

Weirong Pang, Xiaoming Qi, Chunmei Cao, Shuosheng Zhang
Pages: 2207-2215
Published online on: 15 June 2018

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Article

PEP‑1‑glutaredoxin 1 protects against hippocampal neuronal cell damage from oxidative stress via regulation of MAPK and apoptotic signaling pathways

Eun Ji Ryu, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Jung Hwan Park, Su Bin Cho, Chi Hern Lee, Hyeon Ji Yeo, Eun Ji Yeo, Yeon Joo Choi, Duk‑Soo Kim, Sung‑Woo Cho, Yong‑Jun Cho, Eun Jeong Sohn, Ora Son, Keun Wook Lee, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
Pages: 2216-2228
Published online on: 15 June 2018

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Article

miR‑214 mediates vascular inflammation and apoptosis via PTEN expression

Mingliang Wang, Min Liu, Ting Ni, Qiliang Liu
Pages: 2229-2236
Published online on: 18 June 2018

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Article

Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway Expression of Concern in /10.3892/mmr.2025.13679 Corrigendum in /10.3892/mmr.2026.13812 Corrigendum in /10.3892/mmr.2026.13812

Hong‑Yu Meng, De‑Cheng Shao, Han Li, Xiao‑Dan Huang, Guang Yang, Bing Xu, Hai‑Yun Niu
Pages: 2237-2244
Published online on: 19 June 2018

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Article

Identification of open chromosomal regions and key genes in prostate cancer via integrated analysis of DNase‑seq and RNA‑seq data

Xin Wei, Lili Yu, Xuefei Jin, Lide Song, Yanting Lv, Yuping Han
Pages: 2245-2252
Published online on: 19 June 2018

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Article

BM‑MSCs protect against liver ischemia/reperfusion injury via HO‑1 mediated autophagy

Xun Wang, Shuai Wang, Yuan Zhou, Halmurat Obulkasim, Zhi‑Heng Zhang, Bo Dai, Wei Zhu, Xiao‑Lei Shi
Pages: 2253-2262
Published online on: 22 June 2018

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Article

Aclidinium bromide inhibits the growth and metastasis of gastric cancer MKN‑28 cells via the PI3K signaling pathway

Yuanzhi Wang, Ping Cui, Jingjing Liu, Hongxia Wu, Jun Ma
Pages: 2263-2268
Published online on: 25 June 2018

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Article

LncRNA CASC15 promotes colon cancer cell proliferation and metastasis by regulating the miR‑4310/LGR5/Wnt/β‑catenin signaling pathway

Niancai Jing, Tao Huang, Huaiyu Guo, Jili Yang, Mingjing Li, Zhuo Chen, Yue Zhang
Pages: 2269-2276
Published online on: 19 June 2018

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Article

Pyroptosis, a novel mechanism implicated in cataracts

Xin Jin, Hao Jin, Yan Shi, Yiyuan Guo, Hong Zhang
Pages: 2277-2285
Published online on: 19 June 2018

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Article

MicroRNA‑326 inhibits endometrial fibrosis by regulating TGF‑β1/Smad3 pathway in intrauterine adhesions

Jing Ning, Hongtao Zhang, Hongwei Yang
Pages: 2286-2292
Published online on: 19 June 2018

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Article

Serum glycine dehydrogenase is associated with increased risk of lung cancer and promotes malignant transformation by regulating DNA methyltransferases expression

Hai‑Yan Wei, Rui Feng, Hua Shao, Bin Feng, Hong‑Qiang Liu, Jin‑Long Men, Wei Zou
Pages: 2293-2299
Published online on: 22 June 2018

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Article

Captopril inhibits calpain‑mediated apoptosis of myocardial cells in diabetic rats and improves cardiac function

Li‑Ya Dong, Li‑Ping Yao, Jing Zhao, Ke‑Ke Jin, Xiao‑Xiao Qiu
Pages: 2300-2306
Published online on: 19 June 2018

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Article

The close association between IL‑12Rβ2 and p38MAPK, and higher expression in the early stages of NSCLC, indicates a good prognosis for survival

Zhaoguo Liu, Weilin Yang, Shibin Yang, Kaican Cai
Pages: 2307-2313
Published online on: 22 June 2018

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Article

Thymosin β4 promotes endothelial progenitor cell angiogenesis via a vascular endothelial growth factor‑dependent mechanism

Yanbo Zhao, Jiale Song, Xukun Bi, Jing Gao, Zhida Shen, Junhui Zhu, Guosheng Fu
Pages: 2314-2320
Published online on: 20 June 2018

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Article

CNOT1 is involved in TTP‑mediated ICAM‑1 and IL‑8 mRNA decay

Jia‑Xin Shi, Jia‑Shu Li, Rong Hu, Xin‑Cheng Zhao, Cheng‑Cheng Liang, Xiao‑Min Li, Hong Wang, Yi Shi, Xin Su
Pages: 2321-2327
Published online on: 22 June 2018

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Article

miR‑590‑5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5

Wei Cai, Yong Xu, Jian Yin, Wenshan Zuo, Zhen Su
Pages: 2328-2334
Published online on: 15 June 2018

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Article

Intraperitoneal oxaliplatin administration inhibits the tumor immunosuppressive microenvironment in an abdominal implantation model of colon cancer

Hong‑Feng Gou, Lei Zhou, Jia Huang, Xin‑Chuan Chen
Pages: 2335-2341
Published online on: 25 June 2018

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Article

The effects of hyperoxia liquid regulate cardiopulmonary bypass‑induced myocardial damage through the Nrf2‑ARE signaling pathway

Xiaochun Ma, Bin Hu, Chengwei Zou, Aiguo Han, Zhenqiang Xu, Tao Zhang, Wancheng Yu
Pages: 2342-2348
Published online on: 14 June 2018

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Article

Protective properties of spliced X box binding protein 1 in ozone‑induced spinal cord neuronal death

Yun Li, Xu Zhao, Xiaowen Lin, Xuejun Zhao, Juntian Xie, Tao Sun, Zhijian Fu
Pages: 2349-2355
Published online on: 22 June 2018

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Article

JAG1 loss‑of‑function mutations contributed to Alagille syndrome in two Chinese families

Erge Zhang, Yuejuan Xu, Yongguo Yu, Sun Chen, Yu Yu, Kun Sun
Pages: 2356-2364
Published online on: 25 June 2018

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Article

Embelin inhibits abdominal aortic aneurysm through decreasing IL‑6‑induced STAT3 and NF‑κB inactivation

Qiang Liu, Qingshan Wang, Haibin Li
Pages: 2365-2372
Published online on: 26 June 2018

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Article

MicroRNA‑125b regulates Alzheimer's disease through SphK1 regulation

Yan Jin, Qiuyun Tu, Min Liu
Pages: 2373-2380
Published online on: 13 June 2018

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Article

Polymorphism rs7521584 in miR‑429 is associated with the severity of atrophic gastritis in patients with Helicobacter pylori infection

Toshimi Otsuka, Tomomitsu Tahara, Masakatsu Nakamura, Wu Jing, Masafumi Ota, Tomoe Nomura, Ranji Hayashi, Takeo Shimasaki, Tomoyuki Shibata, Tomiyasu Arisawa
Pages: 2381-2386
Published online on: 21 June 2018

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Article

Montelukast inhibits RANKL‑induced osteoclast formation and bone loss via CysLTR1 and P2Y12

Ju‑Hee Kang, Hyungsik Lim, Dong‑Seok Lee, Mijung Yim
Pages: 2387-2398
Published online on: 15 June 2018

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Article

Urinary C‑X‑C motif chemokine 13 is a noninvasive biomarker of antibody‑mediated renal allograft rejection

Dajin Chen, Jian Zhang, Wenhan Peng, Chunhua Weng, Jianghua Chen
Pages: 2399-2406
Published online on: 22 June 2018

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Article

MicroRNA‑485 targets MACC1 and inhibits cervical cancer cell proliferation and invasion Retraction in /10.3892/mmr.2022.12888

Shumei Wang, Yaqi Zhang, Shunping Yuan, Xiaoling Ji
Pages: 2407-2416
Published online on: 18 June 2018

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Article

Association study of frameshift and splice variant polymorphisms with risk of idiopathic recurrent pregnancy loss

Hyun Ah Lee, Eun Hee Ahn, Ji Hyang Kim, Jung Oh Kim, Chang Soo Ryu, Jeong Yong Lee, Sung Hwan Cho, Woo Sik Lee, Nam Keun Kim
Pages: 2417-2426
Published online on: 21 June 2018

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Article

Peroxiredoxin I deficiency increases LPS‑induced lethal shock in mice

Hu‑Nan Sun, Li Feng, Ai‑Guo Wang, Jing‑Yu Wang, Lei Liu, Mei‑Hua Jin, Gui‑Nan Shen, Cheng‑Hao Jin, Dong‑Soek Lee, Tae‑Ho Kwon, Yu‑Dong Cui, Dae‑Yeul Yu, Ying‑Hao Han
Pages: 2427-2432
Published online on: 14 June 2018

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Article

Downregulation of microRNA‑660 inhibits cell proliferation and invasion in osteosarcoma by directly targeting forkhead box O1

Peng Zhang, Haifeng Gao, Qing Li, Xinlei Chen, Xifa Wu
Pages: 2433-2440
Published online on: 14 June 2018

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Article Open Access

Anti-angiogenic activity of Middle East medicinal plants of the Lamiaceae family

Qasem Abdallah, Ibrahim Al‑Deeb, Ammar Bader, Fayez  Hamam, Kamel Saleh, Amin Abdulmajid
Pages: 2441-2448
Published online on: 12 June 2018

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Article

Liraglutide improves cognitive impairment via the AMPK and PI3K/Akt signaling pathways in type 2 diabetic rats

Ying Yang, Hui Fang, Gang Xu, Yanfeng Zhen, Yazhong Zhang, Jinli Tian, Dandan Zhang, Guyue Zhang, Jing Xu
Pages: 2449-2457
Published online on: 18 June 2018

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Article

HAUS8 regulates RLR‑VISA antiviral signaling positively by targeting VISA

Tian‑Sheng He, Tian Chen, Dan‑Dan Wang, Liang‑Guo Xu
Pages: 2458-2466
Published online on: 15 June 2018

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Article

The NRF2‑PGC‑1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, synoviolin, in a cecal ligation/perforation‑induced septic mouse model

Yusuke Ishida, Hidetoshi Fujita, Satoko Aratani, Miyuki Chijiiwa, Noboru Taniguchi, Maho Yokota, Yukihiko Ogihara, Naomi Uoshima, Fumiaki Nagashima, Hiroyuki Uchino, Toshihiro Nakajima
Pages: 2467-2475
Published online on: 15 June 2018

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Article

Methylation profiles of miR34 gene family in Vietnamese patients suffering from breast and lung cancers

Vo Thi Thuong Lan, Ho Van Son, Vu Lan Trang, Nguyen Thu Trang, Nguyen Thi Phuong, Nguyen Linh Toan, Pham Anh Thuy Duong
Pages: 2476-2484
Published online on: 18 June 2018

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Article

Fanconi anemia complementation group C protection against oxidative stress‑induced β‑cell apoptosis

Sirikul Kulanuwat, Prapaporn Jungtrakoon, Watip Tangjittipokin, Pa‑Thai Yenchitsomanus, Nattachet Plengvidhya
Pages: 2485-2491
Published online on: 14 June 2018

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miR‑30a‑5p inhibits the proliferation, migration and invasion of melanoma cells by targeting SOX4 Retraction in /10.3892/mmr.2023.13071

Erbiao Liu, Xiyan Sun, Jinping Li, Chao Zhang
Pages: 2492-2498
Published online on: 14 June 2018

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Assessment of the effects of prostaglandins on myometrial and leiomyoma cells in vitro through microRNA profiling

Hwi Gon Kim, Ga Young Jung, Seung Bin Park, Yeon Jean Cho, Myoungseok Han
Pages: 2499-2505
Published online on: 14 June 2018

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Effects of constrained dynamic loading, CKIP‑1 gene knockout and combination stimulations on bone loss caused by mechanical unloading

Biao Han, Shu‑Ping Wei, Xin‑Chang Zhang, Hao Li, Yu Li, Rui‑Xin Li, Kairen Li, Xi‑Zheng Zhang
Pages: 2506-2514
Published online on: 26 June 2018

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Correction Open Access

[Corrigendum] Differences in atrial fibrillation‑associated proteins between the left and right atrial appendages from patients with rheumatic mitral valve disease: A comparative proteomic analysis

Hai Liu, Guangxian Chen, Hongsheng Zheng, Han Qin, Mengya Liang, Kangni Feng, Zhongkai Wu
Pages: 2515-2515
Published online on: 25 June 2018

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October-2026 Volume 34 Issue 4

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Review

Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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