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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2018 Volume 18 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Cell‑specific histone modifications in atherosclerosis (Review)

Wanlin Jiang, Devendra K. Agrawal, Chandra S. Boosani
Pages: 1215-1224
Published online on: 06 June 2018

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Review Open Access

Computational approaches for predicting key transcription factors in targeted cell reprogramming (Review)

Guillermo‑Issac Guerrero‑Ramirez, Cesar‑Miguel Valdez‑Cordoba, Jose‑Francisco Islas‑Cisneros, Victor Trevino
Pages: 1225-1237
Published online on: 29 May 2018

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Review

Efficacy prediction of targeted therapy for gastric cancer: The current status (Review)

Wanjing Feng, Xiaodong Zhu
Pages: 1238-1246
Published online on: 06 June 2018

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Article

Napsin A is negatively associated with EMT‑mediated EGFR‑TKI resistance in lung cancer cells

Linshui Zhou, Xin Lv, Junchao Yang, Yuanhong Zhu, Zhen Wang, Tingzhen Xu
Pages: 1247-1252
Published online on: 25 May 2018

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Article Open Access

microRNA‑183 is involved in the differentiation and regeneration of Notch signaling‑prohibited hair cells from mouse cochlea

Wei Zhou, Jintao Du, Di Jiang, Xianren Wang, Kaitian Chen, Haocheng Tang, Xuemei Zhang, Hui Cao, Ling Zong, Chang Dong, Hongyan Jiang
Pages: 1253-1262
Published online on: 05 June 2018

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Article Open Access

Identification of genes and signaling pathways associated with the pathogenesis of juvenile spondyloarthritis

Zhe Wang, Yudi Han, Zhaoqing Zhang, Cunfeng Jia, Qiang Zhao, Wei Song, Tao Chen, Yifan Zhang, Xiuhui Wang
Pages: 1263-1270
Published online on: 06 June 2018

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Article Open Access

Differences in the expression profiles of claudin proteins in human gastric carcinoma compared with non‑neoplastic mucosa

Luoluo Yang, Xun Sun, Xiangwei Meng
Pages: 1271-1278
Published online on: 01 June 2018

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Article Open Access

miR‑339‑5p negatively regulates loureirin A‑induced hair follicle stem cell differentiation by targeting DLX5

Xiangjun Li, Yuqiong Wu, Fangfang Xie, Fengxue Zhang, Saixia Zhang, Jianhong Zhou, Dongfeng Chen, Aijun Liu
Pages: 1279-1286
Published online on: 31 May 2018

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Article Open Access

Inflammatory cytokine profile of co‑cultivated primary cells from the endometrium of women with and without endometriosis

Adriana Luckow Invitti, Eduardo Schor, Rafael Martins Parreira, Alexander Kopelman, Gil Kamergorodsky, Giovana Aparecida Gonçalves, Manoel João Batista Castello Girão
Pages: 1287-1296
Published online on: 06 June 2018

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Article Open Access

System analysis of teratozoospermia mRNA profile based on integrated bioinformatics tools

Tiancheng Zhang, Jun Wu, Caihua Liao, Zhong Ni, Jufen Zheng, Fudong Yu
Pages: 1297-1304
Published online on: 31 May 2018

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Article Open Access

CXCL9 promotes prostate cancer progression through inhibition of cytokines from T cells

Shanfeng Tan, Kai Wang, Fuguang Sun, Yang Li, Yisheng Gao
Pages: 1305-1310
Published online on: 11 June 2018

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Article Open Access

Genes associated with inflammation and the cell cycle may serve as biomarkers for the diagnosis and prognosis of acute myocardial infarction in a Chinese population

Jiang Su, Changqing Gao, Rong Wang, Cangsong Xiao, Ming Yang
Pages: 1311-1322
Published online on: 25 May 2018

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Article Open Access

Salvianolic acid B reverses multidrug resistance in nude mice bearing human colon cancer stem cells

Piaoting Guo, Jianchao Wang, Wencang Gao, Xia Liu, Shaofei Wu, Boshun Wan, Lei Xu, Yanhua Li
Pages: 1323-1334
Published online on: 29 May 2018

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Article Open Access

Response of hPDLSCs on 3D printed PCL/PLGA composite scaffolds in vitro

Caixia Peng, Jinxuan Zheng, Dongru Chen, Xueqin Zhang, Lidi Deng, Zhengyuan Chen, Liping Wu
Pages: 1335-1344
Published online on: 25 May 2018

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Article Open Access

Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway

Hao Zhang, Ning Hu
Pages: 1345-1352
Published online on: 01 June 2018

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Article Open Access

Lipid raft‑associated β‑adducin participates in neutrophil migration

Chen Yang, Zhefeng Sui, Tingshuang Xu, Wenai Liu, Xiaoguang Wang, Xianlu Zeng
Pages: 1353-1360
Published online on: 31 May 2018

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Article Open Access

Sipi soup inhibits cancer‑associated fibroblast activation and the inflammatory process by downregulating long non‑coding RNA HIPK1‑AS

Bingxiu Zhou, Yuanyuan Yu, Lixia Yu, Binfu Que, Rui Qiu
Pages: 1361-1368
Published online on: 06 June 2018

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Article Open Access

Fennel main constituent, trans‑anethole treatment against LPS‑induced acute lung injury by regulation of Th17/Treg function

Sichao Zhang, Xi Chen, Ichinkhorloo Devshilt, Qi Yun, Cong Huang, Lijun An, Sosorburam Dorjbat, Xin He
Pages: 1369-1376
Published online on: 07 June 2018

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Article Open Access

Low expression of KCNN3 may affect drug resistance in ovarian cancer

Xia Liu, Luwei Wei, Bingbing Zhao, Xiangxue Cai, Caihua Dong, Fuqiang Yin
Pages: 1377-1386
Published online on: 31 May 2018

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Article Open Access

The roles of the TLR/NF‑κB signaling pathway in the mutual interactions between the lung and the large intestine

Wen Fu, Jing Zhao, Xinglong Liu, Yongxiang Gao, Chuan Zheng
Pages: 1387-1394
Published online on: 31 May 2018

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Article Open Access

miR‑141 inhibits glioma vasculogenic mimicry by controlling EphA2 expression

Guoxiong Li, Min Huang, Yingqian Cai, Yiquan Ke, Yuantao Yang, Xinlin Sun
Pages: 1395-1404
Published online on: 31 May 2018

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Article Open Access

Long non‑coding RNA SENCR alleviates the inhibitory effects of rapamycin on human umbilical vein endothelial cells

Hongtao Sun, Shuiyun Wang, Min Song
Pages: 1405-1414
Published online on: 29 May 2018

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Article Open Access

Screening genes associated with elevated neutrophil‑to‑lymphocyte ratio in chronic heart failure

Guoxing Wan, Lihua Ji, Wenbin Xia, Lan Cheng, Yonggang Zhang
Pages: 1415-1422
Published online on: 05 June 2018

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Article Open Access

A novel APC mutation identified in a large Chinese family with familial adenomatous polyposis and a brief literature review

Minghui Pang, Yijun Liu, Xiaolin Hou, Jialiang Yang, Xuelai He, Nengyi Hou, Peixi Liu, Luo Liang, Junwen Fu, Kang Wang, Zimeng Ye, Bo Gong
Pages: 1423-1432
Published online on: 05 June 2018

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Article Open Access

Curcumin suppresses cardiac fibroblasts activities by regulating the proliferation and cell cycle via the inhibition of the p38 MAPK/ERK signaling pathway

Guanhua Fang, Shaoqin Chen, Qiuyu Huang, Liangwan Chen, Dongshan Liao
Pages: 1433-1438
Published online on: 01 June 2018

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Article Open Access

Protective effect of crocin on ultraviolet B‑induced dermal fibroblast photoaging

Mingwu Deng, Dong Li, Yichen Zhang, Guangdong Zhou, Wei Liu, Yilin Cao, Wenjie Zhang
Pages: 1439-1446
Published online on: 11 June 2018

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Article Open Access

Grape seed proanthocyanidins protect against streptozotocin‑induced diabetic nephropathy by attenuating endoplasmic reticulum stress‑induced apoptosis

Zhaoli Gao, Guangyi Liu, Zhao Hu, Weiwei Shi, Binbin Chen, Peimei Zou, Xianhua Li
Pages: 1447-1454
Published online on: 06 June 2018

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Article Open Access

Physical exercise promotes proliferation and differentiation of endogenous neural stem cells via ERK in rats with cerebral infarction

Wei Liu, Wen Wu, Guangyong Lin, Jian Cheng, Yanyan Zeng, Yu Shi
Pages: 1455-1464
Published online on: 07 June 2018

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Article Open Access

Fibrinogen‑like‑protein 1 promotes the invasion and metastasis of gastric cancer and is associated with poor prognosis

Yang Zhang, Hui‑Xia Qiao, Yong‑Tao Zhou, Liang Hong, Ju‑Hui Chen
Pages: 1465-1472
Published online on: 29 May 2018

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Article Open Access

A three‑lncRNA signature for prognosis prediction of acute myeloid leukemia in patients

Fangce Wang, Xiaoxue Tian, Jie Zhou, Guangming Wang, Wenlei Yu, Zheng Li, Zhuoyi Fan, Wenjun Zhang, Aibin Liang
Pages: 1473-1484
Published online on: 06 June 2018

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Article Open Access

Autophagy protects bone marrow mesenchymal stem cells from palmitate‑induced apoptosis through the ROS‑JNK/p38 MAPK signaling pathways

Yongyi Liu, Ning Wang, Shaokun Zhang, Qingwei Liang
Pages: 1485-1494
Published online on: 30 May 2018

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Article Open Access

Alterations in β‑catenin/E‑cadherin complex formation during the mechanotransduction of Saos‑2 osteoblastic cells

Fei‑Fei Li, Bo Zhang, Ji‑Hong Cui, Fu‑Lin Chen, Yin Ding, Xue Feng
Pages: 1495-1503
Published online on: 07 June 2018

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Article Open Access

Comprehensive evaluation of differential lncRNA and gene expression in patients with intervertebral disc degeneration

Zhigang Qu, Zhe Quan, Qi Zhang, Zhenyu Wang, Qingxu Song, Xinming Zhuang, Changfeng Fu, Feng Xu, Yadong Liu, Yuanyi Wang, Zheng Wang, Yi Liu
Pages: 1504-1512
Published online on: 05 June 2018

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Article Open Access

Identification and functional analysis of differentially expressed genes associated with cerebral ischemia/reperfusion injury through bioinformatics methods

Xiaoli Shao, Wangxiao Bao, Xiaoqin Hong, Huihua Jiang, Zhi Yu
Pages: 1513-1523
Published online on: 06 June 2018

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Article Open Access

miR‑23a downregulation modulates the inflammatory response by targeting ATG12‑mediated autophagy

Xiang Si, Daiyin Cao, Juan Chen, Yao Nie, Zhiyi Jiang, Min‑Ying Chen, Jian‑Feng Wu, Xiang‑Dong Guan
Pages: 1524-1530
Published online on: 29 May 2018

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Article Open Access

A novel method to detect the Mexican founder mutation BRCA1 ex9‑12del associated with breast and ovarian cancer using quantitative polymerase chain reaction and TaqMan® probes

Denisse Aideé Martínez‑Treviño, Rafael Baltazar Reyes León‑Cachón, Cynthia Villarreal‑Garza, Dione Aguilar Y Méndez, Elisa Aguilar‑Martínez, Hugo Alberto Barrera‑Saldaña
Pages: 1531-1537
Published online on: 06 June 2018

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Article Open Access

Identification of candidate biomarkers and pathways associated with SCLC by bioinformatics analysis

Pushuai Wen, Tungamirai Chidanguro, Zhuo Shi, Huanyu Gu, Nan Wang, Tongmei Wang, Yuhong Li, Jing Gao
Pages: 1538-1550
Published online on: 29 May 2018

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Article Open Access

Proteomic profiling for plasma biomarkers of tuberculosis progression

Qiuyue Liu, Liping Pan, Fen Han, Baojian Luo, Hongyan Jia, Aiying Xing, Qi Li, Zongde Zhang
Pages: 1551-1559
Published online on: 05 June 2018

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Article Open Access

Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes subjected to myocardial ischemia‑reperfusion injury via upregulation of the PI3K/Akt pathway

Zhengwen Zhou, Yue Zhang, Luning Lin, Jianmei Zhou
Pages: 1560-1570
Published online on: 31 May 2018

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Article Open Access

Overexpression of retinoblastoma‑binding protein 4 contributes to the radiosensitivity of AGS gastric cancer cells via phosphoinositide3‑kinase/protein kinase B pathway suppression

Xiaoxi Jin, Rui Jiang, Yongsheng Xiang, Zhen Fan, Zhiwei Wu, Bo Yang, Lujun Yang, Shanshan Wei, Yan Yang
Pages: 1571-1581
Published online on: 11 June 2018

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Article Open Access

Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway Corrigendum in /10.3892/mmr.2023.12952

Lin Xu, Xuejun Jiang, Fang Wei, Hongling Zhu
Pages: 1582-1590
Published online on: 29 May 2018

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Article Open Access

miR‑23b inhibits proliferation of SMMC‑7721 cells by directly targeting IL‑11

Tianpeng Jiang, Zhi Huang, Shuai Zhang, Weijie Zou, Lei Xiang, Xiaowen Wu, Yaping Shen, Weixin Liu, Zhu Zeng, Ansu Zhao, Shi Zhou, Qingfan Zeng
Pages: 1591-1599
Published online on: 11 June 2018

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Article Open Access

Induction of apoptosis by Bigelovii A through inhibition of NF‑κB activity

Fuqin Guan, Yu Shan, Qizhi Wang, Ming Wang, Yu Chen, Min Yin, Fei Liu, Youyi Zhao, Jianhua Zhang, Xu Feng
Pages: 1600-1608
Published online on: 30 May 2018

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Article Open Access

SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF‑κB pathway in mouse kupffer cells

Bailin Niu, Kun He, Peizhi Li, Jianping Gong, Xiwen Zhu, Shangmin Ye, Zhibing Ou, Guosheng Ren
Pages: 1609-1615
Published online on: 29 May 2018

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Article Open Access

Long noncoding RNA AFAP1‑AS1 enhances cell proliferation and invasion in osteosarcoma through regulating miR‑4695‑5p/TCF4‑β‑catenin signaling

Rongrui Li, Shichen Liu, Yao Li, Qingxi Tang, Yunchuan Xie, Raosheng Zhai
Pages: 1616-1622
Published online on: 05 June 2018

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Article Open Access

Molecular analysis of Cypriot families with aniridia reveals a novel PAX6 mutation

Andreas Syrimis, Nayia Nicolaou, Angelos Alexandrou, Ioannis Papaevripidou, Michael Nicolaou, Eleni Loukianou, Carolina Sismani, Stavros Malas, Violetta Christophidou‑Anastasiadou, George A. Tanteles
Pages: 1623-1627
Published online on: 05 June 2018

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Article Open Access

Downregulation of miR‑637 promotes proliferation and metastasis by targeting Smad3 in keloids Corrigendum in /10.3892/mmr.2023.13083

Ye Zhang, Bingyu Guo, Qiang Hui, Wei Li, Peng Chang, Kai Tao
Pages: 1628-1636
Published online on: 29 May 2018

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Article Open Access

Pioglitazone restores the homocysteine‑impaired function of endothelial progenitor cells via the inhibition of the protein kinase C/NADPH oxidase pathway

Junhui Zhu, Yanbo Zhao, Lu Yu, Meihui Wang, Qinfeng Li, Shengjie Xu
Pages: 1637-1643
Published online on: 11 June 2018

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Article

CXCR7 silencing inhibits the migration and invasion of human tumor endothelial cells derived from hepatocellular carcinoma by suppressing STAT3

Ye Wu, Lei Tian, Yongle Xu, Minhong Zhang, Shengqing Xiang, Jianguo Zhao, Zhenxia Wang
Pages: 1644-1650
Published online on: 31 May 2018

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Article

Obovatol inhibits the growth and aggressiveness of tongue squamous cell carcinoma through regulation of the EGF‑mediated JAK‑STAT signaling pathway

Mingli Duan, Xiaoming Du, Gang Ren, Yongdong Zhang, Yu Zheng, Shuping Sun, Jun Zhang
Pages: 1651-1659
Published online on: 25 May 2018

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Article

Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts

Yiqun Sun, Haiyang Jiang, Ming Gu, Xinyu Zheng
Pages: 1660-1665
Published online on: 30 May 2018

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Article

miRNA‑195 suppresses cell proliferation of ovarian cancer cell by regulating VEGFR2 and AKT signaling pathways

Jun Chen
Pages: 1666-1673
Published online on: 29 May 2018

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Article

miR‑205 targets YAP1 and inhibits proliferation and invasion in thyroid cancer cells

Dewei Li, Qiang Wang, Ning Li, Shuilong Zhang
Pages: 1674-1681
Published online on: 25 May 2018

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Article

Bushen recipe and its disassembled prescriptions inhibit inflammation of liver injury associated with Concanavalin A through Toll‑like receptor 3/9 signaling pathway

Hongming Nie, Zhaohe Mei, Rong Wang, Binbin Zhao, Yueqiu Gao, Jianjie Chen, Lingtai Wang
Pages: 1682-1691
Published online on: 29 May 2018

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Article

Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkin‑mediated mitophagy by suppressing AMPK/Skp2 pathways Retraction in /10.3892/mmr.2024.13315

Lili He, Kebo Gu
Pages: 1692-1703
Published online on: 29 May 2018

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Article

Increased B cell activating factor is associated with B cell class switching in patients with tuberculous pleural effusion

Xin Wang, Kui‑Di Liang, Jun‑Ai Zhang, Gan‑Bin Liu, Zhi Chen, Chen Chen, Ze‑Gang Zhuang, Yu‑Qing Liu, Hou‑Long Luo, Rui Xi Li, Bi‑Ying Zheng, Jun‑Fa Xu
Pages: 1704-1709
Published online on: 25 May 2018

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Article

Hypoxia induces lactate secretion and glycolytic efflux by downregulating mitochondrial pyruvate carrier levels in human umbilical vein endothelial cells

Dong Wang, Qingjie Wang, Gaoliang Yan, Yong Qiao, Boqian Zhu, Bo Liu, Chengchun Tang
Pages: 1710-1717
Published online on: 29 May 2018

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Article

Reduction in activating transcription factor 4 promotes carbon tetrachloride and lipopolysaccharide/D‑galactosamine‑mediated liver injury in mice

Xiaofang Zhao, Hong Zhou, Ying Cheng, Wenjing Yu, Guosong Luo, Chunyan Duan, Fuli Yao, Bin Xiao, Chunhong Feng, Xianming Xia, Mei Wei, Yong Wang, Jing Li, Rongyang Dai
Pages: 1718-1725
Published online on: 29 May 2018

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Article

Association between age‑related hearing loss and cognitive decline in C57BL/6J mice

Yang Dong, Chun‑Rong Guo, Dan Chen, Sheng‑Min Chen, Yinting Peng, Haiyan Song, Jian‑Rong Shi
Pages: 1726-1732
Published online on: 01 June 2018

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Article

Epithelial‑mesenchymal transition was identified as a potential marker for breast cancer aggressiveness using reverse transcription‑quantitative polymerase chain reaction

Ulrich Andergassen, Kristina Schlenk, Udo Jeschke, Harald Sommer, Alexandra Kölbl
Pages: 1733-1739
Published online on: 29 May 2018

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Article

Effects of microRNA‑210 on the diagnosis and treatment of prostate cancer

Yuejun Qu, Wenqiang Huang
Pages: 1740-1744
Published online on: 31 May 2018

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Article

Upregulation of miR‑122 is associated with cardiomyocyte apoptosis in atrial fibrillation

Xiangqun Zhang, Wenli Jing
Pages: 1745-1751
Published online on: 04 June 2018

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Article

Protective effects of scoparone against ischemia‑reperfusion‑induced myocardial injury

Chunfu Wan, Yueyue Wei, Jianguo Ma, Xiaoyong Geng
Pages: 1752-1760
Published online on: 04 June 2018

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Case Report

Novel HSPG2 mutations causing Schwartz‑Jampel syndrome type 1 in a Chinese family: A case report

Wenjin Yan, Jin Dai, Dongquan Shi, Xingquan Xu, Xiao Han, Zhihong Xu, Dongyang Chen, Huajiang Teng, Qing Jiang
Pages: 1761-1765
Published online on: 06 June 2018

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Article

Integrated computational biology analysis to evaluate target genes for chronic myelogenous leukemia

Yu Zheng, Yu‑Ping Wang, Hongbao Cao, Qiusheng Chen, Xi Zhang
Pages: 1766-1772
Published online on: 05 June 2018

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Article

Organ‑specific expression of the divalent ion channel proteins NCKX3, TRPV2, CTR1, ATP7A, IREG1 and HEPH in various canine organs

Changhwan Ahn, Jong‑Sam Choi, Eui‑Bae Jeung
Pages: 1773-1781
Published online on: 07 June 2018

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Article

TROP2 promotes cell proliferation and migration in osteosarcoma through PI3K/AKT signaling

Qing‑Zhi Gu, Abulimiti Nijiati, Xing Gao, Kai‑Liang Tao, Cheng‑Duo Li, Xue‑Peng Fan, Zheng Tian
Pages: 1782-1788
Published online on: 29 May 2018

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Article

Glucagon‑like peptide‑1 protects mouse podocytes against high glucose‑induced apoptosis, and suppresses reactive oxygen species production and proinflammatory cytokine secretion, through sirtuin 1 activation in vitro

Jian‑Xia Shi, Qin Huang
Pages: 1789-1797
Published online on: 29 May 2018

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Article

CXCL8 and CXCL11 chemokine secretion in dermal fibroblasts is differentially modulated by vanadium pentoxide

P. Fallahi, R. Foddis, G. Elia, F. Ragusa, A. Patrizio, S. Benvenga, A. Cristaudo, A. Antonelli, S. M. Ferrari
Pages: 1798-1803
Published online on: 01 June 2018

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Article

MicroRNA‑539 inhibits cell proliferation, colony formation and invasion in pancreatic ductal adenocarcinoma by directly targeting IGF‑1R

Yongquan Lin, Lihua Rong, Jingrong Zhao, Ronghui Lin, Shuhua Li
Pages: 1804-1811
Published online on: 31 May 2018

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Article

MicroRNA‑199b promotes cell proliferation and invasion in Wilms' tumour by directly targeting Runt‑related transcription factor 3

Huizhen Zhao, Hailing Zhao, Yongna Zhang, Yuxi Zhou
Pages: 1812-1819
Published online on: 29 May 2018

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Article

MG‑132 reverses multidrug resistance by activating the JNK signaling pathway in FaDu/T cells

Juke Ma, Zhenghua Lv, Xiuxiu Liu, Xianfang Liu, Wei Xu
Pages: 1820-1825
Published online on: 06 June 2018

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Article

microRNA‑574 inhibits cell proliferation and invasion in glioblastoma multiforme by directly targeting zinc finger E‑box‑binding homeobox 1 Retraction in /10.3892/mmr.2022.12884

Youyan Mao, Fangmeng Wei, Chenghong Wei, Chengjun Wei
Pages: 1826-1834
Published online on: 31 May 2018

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Article

Synergistic apoptotic effects of silibinin in enhancing paclitaxel toxicity in human gastric cancer cell lines

Yuanxin Zhang, Yakun Ge, Xie Ping, Ming Yu, Dawei Lou, Wei Shi
Pages: 1835-1841
Published online on: 05 June 2018

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Article

B7‑H1‑mediated immunosuppressive properties in human mesenchymal stem cells are mediated by STAT‑1 and not PI3K/Akt signaling

In Keun Jang, Hyun Joo Jung, O Kyu Noh, Doo‑Hoon Lee, Kwang Chul Lee, Jun Eun Park
Pages: 1842-1848
Published online on: 30 May 2018

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Article

Effects of strontium ranelate on wear particle‑induced aseptic loosening in female ovariectomized mice

Tianxiang Geng, Xi Chen, Mengxue Zheng, Haochen Yu, Shuai Zhang, Shouxuan Sun, Haohui Guo, Qunhua Jin
Pages: 1849-1857
Published online on: 05 June 2018

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Article

Protective effect of Letinous edodes foot peptides against ethanol‑induced liver injury in L02 cells

Lin Ma, Chun‑Yan Huo, Xiao‑Yu Zhang, Chen‑Qiang Qin, Di‑Feng Ren, Jun Lu
Pages: 1858-1866
Published online on: 29 May 2018

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Article

Oxidative stress modulates the expression of toll‑like receptor 3 during respiratory syncytial virus infection in human lung epithelial A549 cells

Min‑Min Wang, Min Lu, Chuan‑Long Zhang, Xuan Wu, Jing‑Xian Chen, Wei‑Wei Lv, Tao Sun, Huan Qiu, Sheng‑Hai Huang
Pages: 1867-1877
Published online on: 29 May 2018

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Article

MicroRNA‑655 inhibits cell proliferation and invasion in epithelial ovarian cancer by directly targeting vascular endothelial growth factor Retraction in /10.3892/mmr.2022.12860

Ziling Zhao, Shuna Yang, Yan Cheng, Xiuhua Zhao
Pages: 1878-1884
Published online on: 29 May 2018

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Article

The effect of Mg‑2Zn‑0.5Nd alloy on the mTOR signalling pathway in L6 cells

Wei Lu, Lei Guo, Tianlong Jiang, Shenghui Ni, Yuyan Zhao
Pages: 1885-1891
Published online on: 30 May 2018

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Correction Open Access

[Corrigendum] Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice

Bing He, Xiaoou Li, Tuo Hu, Wenjing Lian, Mingxia Zhang
Pages: 1892-1892
Published online on: 01 June 2018

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Correction Open Access

[Corrigendum] microRNA‑181a‑5p functions as an oncogene in renal cell carcinoma

Yulin Lai, Liwen Zhao, Jia Hu, Jing Quan, Peijie Chen, Jinling Xu, Xin Guan, Yongqing Lai, Liangchao Ni
Pages: 1893-1893
Published online on: 01 June 2018

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Article Open Access

Tanshinone IIA improves hypoxic ischemic encephalopathy through TLR‑4‑mediated NF‑κB signal pathway Retraction in /10.3892/mmr.2025.13428

Chengzhi Fang, Lili Xie, Chunmei Liu, Chunhua Fu, Wei Ye, Hong Liu, Binghong Zhang
Pages: 1899-1908
Published online on: 26 June 2018

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Article Open Access

MicroRNA expression profiles identify biomarkers for predicting the response to chemoradiotherapy in rectal cancer

Binbin Du, Xiaoying Wang, Dewang Wu, Tao Wang, Xiongfei Yang, Jiankai Wang, Xinlong Shi, Lingjuan Chen, Weisheng Zhang
Pages: 1909-1916
Published online on: 25 June 2018

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Article Open Access

Regulatory effects of microRNA‑184 on osteosarcoma via the Wnt/β‑catenin signaling pathway

Zhenguang Du, Fusheng Li, Liangliang Wang, Hai Huang, Shaonian Xu
Pages: 1917-1924
Published online on: 18 June 2018

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Article Open Access

Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats

Dandan Song, Xuelei Liu, Yugang Diao, Yingjie Sun, Guangjie Gao, Tiezheng Zhang, Keyan Chen, Ling Pei
Pages: 1925-1938
Published online on: 20 June 2018

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Article Open Access

Effect of survivin downregulation by simvastatin on the growth and invasion of salivary adenoid cystic carcinoma

Wen‑Yan Cai, Ying Zhuang, Fei Yan, Ting Li, Wen‑Ting Song, Jin‑Hu Sun
Pages: 1939-1946
Published online on: 22 June 2018

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Article Open Access

HBx gene transfection affects the cycle of primary renal tubular epithelial cells through regulating cyclin expression

Wenlun Han, Meiliang Luo, Mengying He, Yunyun Zhu, Yu Zhong, Huideng Ding, Gang Hu, Liansheng Liu, Qin Chen, Ying Lu
Pages: 1947-1954
Published online on: 20 June 2018

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Article Open Access

Weighted gene co‑expression network analysis in identification of key genes and networks for ischemic‑reperfusion remodeling myocardium

Nan Guo, Nan Zhang, Liqiu Yan, Zheng Lian, Jiawang Wang, Fengfeng Lv, Yunfei Wang, Xufen Cao
Pages: 1955-1962
Published online on: 14 June 2018

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Article Open Access

Detection of dysregulated competing endogenous RNA modules associated with clear cell kidney carcinoma

Hong Wang, Dahua Xu, Huiying Huang, Ying Cui, Chunhua Li, Chunrui Zhang, Shengnan Guo, Lining Zhang, Xiaomu Xu, Jiankai Xu, Jianping Lu, Liqiang Wang, Kongning Li
Pages: 1963-1972
Published online on: 19 June 2018

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Article Open Access

Interaction with adipocytes induces lung adenocarcinoma A549 cell migration and tumor growth

Fan-Fan Li, Hang Zhang, Jing-Jing Li, Ya-Nan Cao, Xiang Dong, Cong Gao
Pages: 1973-1980
Published online on: 26 June 2018

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Article Open Access

Antioxidants retard the ageing of mouse oocytes

Yexing Xian, Lifeng Liang, Shutao Qi, Yingjun Xie, Bing Song, Shuming Ouyang, Yuhuan Xie, Xiaofang Sun, Weihua Wang
Pages: 1981-1986
Published online on: 14 June 2018

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Article Open Access

Protective effect of KLF15 on vascular endothelial dysfunction induced by TNF‑α

Bing Liu, Lili Xu, Xinming Yu, Wei Li, Xiaozhi Sun, Shun Xiao, Mingjin Guo, Haofu Wang
Pages: 1987-1994
Published online on: 20 June 2018

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Article Open Access

Spleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome‑mediated IL‑1β secretion via c‑Jun N‑terminal kinase activation and cell apoptosis during diabetic nephropathy

Yingchun Qiao, Xixi Tian, Li Men, Shengyu Li, Yufeng Chen, Meiting Xue, Yahui Hu, Pengfei Zhou, Guangfeng Long, Yue Shi, Ruiqing Liu, Yunde Liu, Zhi Qi, Yujie Cui, Yanna Shen
Pages: 1995-2008
Published online on: 14 June 2018

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Article Open Access

Differentiation of umbilical cord mesenchymal stem cells into hepatocytes in comparison with bone marrow mesenchymal stem cells

Ya‑Bin Yu, Yan Song, Ya Chen, Feng Zhang, Fu‑Zhen Qi
Pages: 2009-2016
Published online on: 18 June 2018

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Article Open Access

Application of 460 nm visible light for the elimination of Candida albicans in vitro and in vivo

Chuan Wang, Zhiyin Yang, Yinbo Peng, Yuanyuan Guo, Min Yao, Jiying Dong
Pages: 2017-2026
Published online on: 20 June 2018

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Article Open Access

Whole‑exome sequencing analysis of products of conception identifies novel mutations associated with missed abortion

Meng Fu, Sha Mu, Chunyan Wen, Shufang Jiang, Lin Li, Yuanguang Meng, Hongmei Peng
Pages: 2027-2032
Published online on: 21 June 2018

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Article Open Access

Effects of isomaltulose on insulin resistance and metabolites in patients with non‑alcoholic fatty liver disease: A metabolomic analysis

Takumi Kawaguchi, Dan Nakano, Tetsuharu Oriishi, Takuji Torimura
Pages: 2033-2042
Published online on: 26 June 2018

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Article Open Access

YC‑1 reduces inflammatory responses by inhibiting nuclear factor‑κB translocation in mice subjected to transient focal cerebral ischemia

Wei‑Ting Lee, Shih‑Huang Tai, Yu‑Wen Lin, Tian‑Shung Wu, E‑Jian Lee
Pages: 2043-2051
Published online on: 15 June 2018

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Article Open Access

Expression of vitamin D receptor in bronchial asthma and its bioinformatics prediction

Lishen Shan, Xinyuan Kang, Fen Liu, Xuxu Cai, Xiaohua Han, Yunxiao Shang
Pages: 2052-2060
Published online on: 13 June 2018

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Article Open Access

TIMP‑3 suppresses the proliferation and migration of SMCs from the aortic neck of atherosclerotic AAA in rabbits, via decreased MMP‑2 and MMP‑9 activity, and reduced TNF‑α expression

Huan Zhai, Xun Qi, Zixuan Li, Wei Zhang, Chenguang Li, Lu Ji, Ke Xu, Hongshan Zhong
Pages: 2061-2067
Published online on: 26 June 2018

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Article Open Access

Antitumor effects of Xi Huang pills on MDA‑MB‑231 cells in vitro and in vivo

Wenxian Zheng, Shuyan Han, Shantong Jiang, Xiran He, Xiaohong Li, Huirong Ding, Minhua Cao, Pingping Li
Pages: 2068-2078
Published online on: 21 June 2018

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Label‑free quantitative proteomics and bioinformatics analyses of alcoholic liver disease in a chronic and binge mouse model

Yu Zhang, Cheng Zhan, Genwen Chen, Jianyong Sun
Pages: 2079-2087
Published online on: 26 June 2018

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Article Open Access

Epigallocatechin gallate improves airway inflammation through TGF‑β1 signaling pathway in asthmatic mice

Lishen Shan, Xinyuan Kang, Fen Liu, Xuxu Cai, Xiaohua Han, Yunxiao Shang
Pages: 2088-2096
Published online on: 18 June 2018

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Article Open Access

Characteristics and multi‑lineage differentiation of bone marrow mesenchymal stem cells derived from the Tibetan mastiff

Shuang Zhang, Chenqiong Zhao, Shi Liu, Yufeng Wang, Yuhua Zhao, Weijun Guan, Zhiqiang Zhu
Pages: 2097-2109
Published online on: 15 June 2018

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C5a aggravates dysfunction of the articular cartilage and synovial fluid in rats with knee joint immobilization

Wei Lu, Lin Wang, Jing Yao, Chunxin Wo, Yu Chen
Pages: 2110-2116
Published online on: 22 June 2018

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Article Open Access

Amplification of bacterial genomic DNA from all ascitic fluids with a highly sensitive polymerase chain reaction

Hirayuki Enomoto, Shin‑Ichi Inoue, Akio Matsuhisa, Yoshinori Iwata, Nobuhiro Aizawa, Yoshiyuki Sakai, Ryo Takata, Naoto Ikeda, Kunihiro Hasegawa, Chikage Nakano, Takashi Nishimura, Kazunori Yoh, Yuho Miyamoto, Noriko Ishii, Yukihisa Yuri, Akio Ishii, Tomoyuki Takashima, Hiroki Nishikawa, Hiroko Iijima, Shuhei Nishiguchi
Pages: 2117-2123
Published online on: 14 June 2018

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Article Open Access

Inhibition of autophagy enhanced cobalt chloride‑induced apoptosis in rat alveolar type II epithelial cells

Yan Yu, Wanting Li, Liqin Ren, Chunyan Yang, Dongze Li, Xin Han, Yeying Sun, Changjun Lv, Fang Han
Pages: 2124-2132
Published online on: 22 June 2018

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Article Open Access

Effect of electric stimulation on human chondrocytes and mesenchymal stem cells under normoxia and hypoxia

Bettina Hiemer, Martin Krogull, Thomas Bender, Josefin Ziebart, Simone Krueger, Rainer Bader, Anika Jonitz‑Heincke
Pages: 2133-2141
Published online on: 15 June 2018

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Article Open Access

N‑terminal truncated peroxisome proliferator‑activated receptor‑γ coactivator‑1α alleviates phenylephrine‑induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes

Zuheng Liu, Jinghai Hua, Wanqiang Cai, Qiong Zhan, Wenyan Lai, Qingchun Zeng, Hao Ren, Dingli Xu
Pages: 2142-2152
Published online on: 14 June 2018

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Identification of differentially expressed genes associated with asthma in children based on the bioanalysis of the regulatory network

Chunyan Wang, Hengtao Li, Lanfang Cao, Genzai Wang
Pages: 2153-2163
Published online on: 22 June 2018

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Article Open Access

Identification of a noncoding RNA‑mediated gene pair‑based regulatory module in Alzheimer's disease

Lin Yu, Shi Qian, Sun Wei
Pages: 2164-2170
Published online on: 19 June 2018

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Article Open Access

Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide‑induced intestinal injury

Ying Xiong, Kai‑Xue Li, Hong Wei, Lu Jiao, Shao‑Yong Yu, Li Zeng
Pages: 2171-2181
Published online on: 14 June 2018

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Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer

Yu Jiang, Gang Liu, Li Zhang, Sheng Cheng, Chun Luo, Yang Liao, Shuliang Guo
Pages: 2182-2190
Published online on: 14 June 2018

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Article Open Access

Next‑generation sequencing‑based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her‑2 and TP53 mutations in patients with non‑small cell lung cancer

Changwen Jing, Xuhua Mao, Zhuo Wang, Kejing Sun, Rong Ma, Jianzhong Wu, Haixia Cao
Pages: 2191-2197
Published online on: 22 June 2018

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Article Open Access

Recombinant club cell protein 16 (CC16) ameliorates cigarette smoke‑induced lung inflammation in a murine disease model of COPD

Min Pang, Hong‑Yan Liu, Ting Li, Dan Wang, Xiao‑Yun Hu, Xin‑Ri Zhang, Bao‑Feng Yu, Rui Guo, Hai‑Long Wang
Pages: 2198-2206
Published online on: 25 June 2018

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Article

Inhibitory effects of TGP on KGF‑induced hyperproliferation of HaCaT cells via suppression of the p38 MAPK/NF‑κB p65 pathway

Weirong Pang, Xiaoming Qi, Chunmei Cao, Shuosheng Zhang
Pages: 2207-2215
Published online on: 15 June 2018

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Article

PEP‑1‑glutaredoxin 1 protects against hippocampal neuronal cell damage from oxidative stress via regulation of MAPK and apoptotic signaling pathways

Eun Ji Ryu, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Jung Hwan Park, Su Bin Cho, Chi Hern Lee, Hyeon Ji Yeo, Eun Ji Yeo, Yeon Joo Choi, Duk‑Soo Kim, Sung‑Woo Cho, Yong‑Jun Cho, Eun Jeong Sohn, Ora Son, Keun Wook Lee, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
Pages: 2216-2228
Published online on: 15 June 2018

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Article

miR‑214 mediates vascular inflammation and apoptosis via PTEN expression

Mingliang Wang, Min Liu, Ting Ni, Qiliang Liu
Pages: 2229-2236
Published online on: 18 June 2018

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Article

Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway Expression of Concern in /10.3892/mmr.2025.13679

Hong‑Yu Meng, De‑Cheng Shao, Han Li, Xiao‑Dan Huang, Guang Yang, Bing Xu, Hai‑Yun Niu
Pages: 2237-2244
Published online on: 19 June 2018

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Article

Identification of open chromosomal regions and key genes in prostate cancer via integrated analysis of DNase‑seq and RNA‑seq data

Xin Wei, Lili Yu, Xuefei Jin, Lide Song, Yanting Lv, Yuping Han
Pages: 2245-2252
Published online on: 19 June 2018

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Article

BM‑MSCs protect against liver ischemia/reperfusion injury via HO‑1 mediated autophagy

Xun Wang, Shuai Wang, Yuan Zhou, Halmurat Obulkasim, Zhi‑Heng Zhang, Bo Dai, Wei Zhu, Xiao‑Lei Shi
Pages: 2253-2262
Published online on: 22 June 2018

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Article

Aclidinium bromide inhibits the growth and metastasis of gastric cancer MKN‑28 cells via the PI3K signaling pathway

Yuanzhi Wang, Ping Cui, Jingjing Liu, Hongxia Wu, Jun Ma
Pages: 2263-2268
Published online on: 25 June 2018

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Article

LncRNA CASC15 promotes colon cancer cell proliferation and metastasis by regulating the miR‑4310/LGR5/Wnt/β‑catenin signaling pathway

Niancai Jing, Tao Huang, Huaiyu Guo, Jili Yang, Mingjing Li, Zhuo Chen, Yue Zhang
Pages: 2269-2276
Published online on: 19 June 2018

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Article

Pyroptosis, a novel mechanism implicated in cataracts

Xin Jin, Hao Jin, Yan Shi, Yiyuan Guo, Hong Zhang
Pages: 2277-2285
Published online on: 19 June 2018

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Article

MicroRNA‑326 inhibits endometrial fibrosis by regulating TGF‑β1/Smad3 pathway in intrauterine adhesions

Jing Ning, Hongtao Zhang, Hongwei Yang
Pages: 2286-2292
Published online on: 19 June 2018

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Article

Serum glycine dehydrogenase is associated with increased risk of lung cancer and promotes malignant transformation by regulating DNA methyltransferases expression

Hai‑Yan Wei, Rui Feng, Hua Shao, Bin Feng, Hong‑Qiang Liu, Jin‑Long Men, Wei Zou
Pages: 2293-2299
Published online on: 22 June 2018

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Article

Captopril inhibits calpain‑mediated apoptosis of myocardial cells in diabetic rats and improves cardiac function

Li‑Ya Dong, Li‑Ping Yao, Jing Zhao, Ke‑Ke Jin, Xiao‑Xiao Qiu
Pages: 2300-2306
Published online on: 19 June 2018

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Article

The close association between IL‑12Rβ2 and p38MAPK, and higher expression in the early stages of NSCLC, indicates a good prognosis for survival

Zhaoguo Liu, Weilin Yang, Shibin Yang, Kaican Cai
Pages: 2307-2313
Published online on: 22 June 2018

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Article

Thymosin β4 promotes endothelial progenitor cell angiogenesis via a vascular endothelial growth factor‑dependent mechanism

Yanbo Zhao, Jiale Song, Xukun Bi, Jing Gao, Zhida Shen, Junhui Zhu, Guosheng Fu
Pages: 2314-2320
Published online on: 20 June 2018

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Article

CNOT1 is involved in TTP‑mediated ICAM‑1 and IL‑8 mRNA decay

Jia‑Xin Shi, Jia‑Shu Li, Rong Hu, Xin‑Cheng Zhao, Cheng‑Cheng Liang, Xiao‑Min Li, Hong Wang, Yi Shi, Xin Su
Pages: 2321-2327
Published online on: 22 June 2018

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Article

miR‑590‑5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5

Wei Cai, Yong Xu, Jian Yin, Wenshan Zuo, Zhen Su
Pages: 2328-2334
Published online on: 15 June 2018

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Article

Intraperitoneal oxaliplatin administration inhibits the tumor immunosuppressive microenvironment in an abdominal implantation model of colon cancer

Hong‑Feng Gou, Lei Zhou, Jia Huang, Xin‑Chuan Chen
Pages: 2335-2341
Published online on: 25 June 2018

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Article

The effects of hyperoxia liquid regulate cardiopulmonary bypass‑induced myocardial damage through the Nrf2‑ARE signaling pathway

Xiaochun Ma, Bin Hu, Chengwei Zou, Aiguo Han, Zhenqiang Xu, Tao Zhang, Wancheng Yu
Pages: 2342-2348
Published online on: 14 June 2018

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Article

Protective properties of spliced X box binding protein 1 in ozone‑induced spinal cord neuronal death

Yun Li, Xu Zhao, Xiaowen Lin, Xuejun Zhao, Juntian Xie, Tao Sun, Zhijian Fu
Pages: 2349-2355
Published online on: 22 June 2018

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Article

JAG1 loss‑of‑function mutations contributed to Alagille syndrome in two Chinese families

Erge Zhang, Yuejuan Xu, Yongguo Yu, Sun Chen, Yu Yu, Kun Sun
Pages: 2356-2364
Published online on: 25 June 2018

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Article

Embelin inhibits abdominal aortic aneurysm through decreasing IL‑6‑induced STAT3 and NF‑κB inactivation

Qiang Liu, Qingshan Wang, Haibin Li
Pages: 2365-2372
Published online on: 26 June 2018

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Article

MicroRNA‑125b regulates Alzheimer's disease through SphK1 regulation

Yan Jin, Qiuyun Tu, Min Liu
Pages: 2373-2380
Published online on: 13 June 2018

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Article

Polymorphism rs7521584 in miR‑429 is associated with the severity of atrophic gastritis in patients with Helicobacter pylori infection

Toshimi Otsuka, Tomomitsu Tahara, Masakatsu Nakamura, Wu Jing, Masafumi Ota, Tomoe Nomura, Ranji Hayashi, Takeo Shimasaki, Tomoyuki Shibata, Tomiyasu Arisawa
Pages: 2381-2386
Published online on: 21 June 2018

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Article

Montelukast inhibits RANKL‑induced osteoclast formation and bone loss via CysLTR1 and P2Y12

Ju‑Hee Kang, Hyungsik Lim, Dong‑Seok Lee, Mijung Yim
Pages: 2387-2398
Published online on: 15 June 2018

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Article

Urinary C‑X‑C motif chemokine 13 is a noninvasive biomarker of antibody‑mediated renal allograft rejection

Dajin Chen, Jian Zhang, Wenhan Peng, Chunhua Weng, Jianghua Chen
Pages: 2399-2406
Published online on: 22 June 2018

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Article

MicroRNA‑485 targets MACC1 and inhibits cervical cancer cell proliferation and invasion Retraction in /10.3892/mmr.2022.12888

Shumei Wang, Yaqi Zhang, Shunping Yuan, Xiaoling Ji
Pages: 2407-2416
Published online on: 18 June 2018

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Article

Association study of frameshift and splice variant polymorphisms with risk of idiopathic recurrent pregnancy loss

Hyun Ah Lee, Eun Hee Ahn, Ji Hyang Kim, Jung Oh Kim, Chang Soo Ryu, Jeong Yong Lee, Sung Hwan Cho, Woo Sik Lee, Nam Keun Kim
Pages: 2417-2426
Published online on: 21 June 2018

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Article

Peroxiredoxin I deficiency increases LPS‑induced lethal shock in mice

Hu‑Nan Sun, Li Feng, Ai‑Guo Wang, Jing‑Yu Wang, Lei Liu, Mei‑Hua Jin, Gui‑Nan Shen, Cheng‑Hao Jin, Dong‑Soek Lee, Tae‑Ho Kwon, Yu‑Dong Cui, Dae‑Yeul Yu, Ying‑Hao Han
Pages: 2427-2432
Published online on: 14 June 2018

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Article

Downregulation of microRNA‑660 inhibits cell proliferation and invasion in osteosarcoma by directly targeting forkhead box O1

Peng Zhang, Haifeng Gao, Qing Li, Xinlei Chen, Xifa Wu
Pages: 2433-2440
Published online on: 14 June 2018

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Anti-angiogenic activity of Middle East medicinal plants of the Lamiaceae family

Qasem Abdallah, Ibrahim Al‑Deeb, Ammar Bader, Fayez  Hamam, Kamel Saleh, Amin Abdulmajid
Pages: 2441-2448
Published online on: 12 June 2018

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Article

Liraglutide improves cognitive impairment via the AMPK and PI3K/Akt signaling pathways in type 2 diabetic rats

Ying Yang, Hui Fang, Gang Xu, Yanfeng Zhen, Yazhong Zhang, Jinli Tian, Dandan Zhang, Guyue Zhang, Jing Xu
Pages: 2449-2457
Published online on: 18 June 2018

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Article

HAUS8 regulates RLR‑VISA antiviral signaling positively by targeting VISA

Tian‑Sheng He, Tian Chen, Dan‑Dan Wang, Liang‑Guo Xu
Pages: 2458-2466
Published online on: 15 June 2018

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Article

The NRF2‑PGC‑1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, synoviolin, in a cecal ligation/perforation‑induced septic mouse model

Yusuke Ishida, Hidetoshi Fujita, Satoko Aratani, Miyuki Chijiiwa, Noboru Taniguchi, Maho Yokota, Yukihiko Ogihara, Naomi Uoshima, Fumiaki Nagashima, Hiroyuki Uchino, Toshihiro Nakajima
Pages: 2467-2475
Published online on: 15 June 2018

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Article

Methylation profiles of miR34 gene family in Vietnamese patients suffering from breast and lung cancers

Vo Thi Thuong Lan, Ho Van Son, Vu Lan Trang, Nguyen Thu Trang, Nguyen Thi Phuong, Nguyen Linh Toan, Pham Anh Thuy Duong
Pages: 2476-2484
Published online on: 18 June 2018

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Article

Fanconi anemia complementation group C protection against oxidative stress‑induced β‑cell apoptosis

Sirikul Kulanuwat, Prapaporn Jungtrakoon, Watip Tangjittipokin, Pa‑Thai Yenchitsomanus, Nattachet Plengvidhya
Pages: 2485-2491
Published online on: 14 June 2018

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Article

miR‑30a‑5p inhibits the proliferation, migration and invasion of melanoma cells by targeting SOX4 Retraction in /10.3892/mmr.2023.13071

Erbiao Liu, Xiyan Sun, Jinping Li, Chao Zhang
Pages: 2492-2498
Published online on: 14 June 2018

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Assessment of the effects of prostaglandins on myometrial and leiomyoma cells in vitro through microRNA profiling

Hwi Gon Kim, Ga Young Jung, Seung Bin Park, Yeon Jean Cho, Myoungseok Han
Pages: 2499-2505
Published online on: 14 June 2018

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Effects of constrained dynamic loading, CKIP‑1 gene knockout and combination stimulations on bone loss caused by mechanical unloading

Biao Han, Shu‑Ping Wei, Xin‑Chang Zhang, Hao Li, Yu Li, Rui‑Xin Li, Kairen Li, Xi‑Zheng Zhang
Pages: 2506-2514
Published online on: 26 June 2018

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[Corrigendum] Differences in atrial fibrillation‑associated proteins between the left and right atrial appendages from patients with rheumatic mitral valve disease: A comparative proteomic analysis

Hai Liu, Guangxian Chen, Hongsheng Zheng, Han Qin, Mengya Liang, Kangni Feng, Zhongkai Wu
Pages: 2515-2515
Published online on: 25 June 2018

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January-2026 Volume 33 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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