|
1
|
Ertunc ME and Hotamisligil GS: Lipid
signaling and lipotoxicity in metaflammation: Indications for
metabolic disease pathogenesis and treatment. J Lipid Res.
57:2099–2114. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Du X, Shi Z, Peng Z, Zhao C, Zhang Y, Wang
Z and Li X, Liu G and Li X: Acetoacetate induces hepatocytes
apoptosis by the ROS-mediated MAPKs pathway in ketotic cows. J Cell
Physiol. 232:3296–3308. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Nemoto K, Ikeda A, Yoshida C, Kimura J,
Mori J, Fujiwara H, Yokosuka A, Mimaki Y, Ohizumi Y and Degawa M:
Characteristics of nobiletin-mediated alteration of gene expression
in cultured cell lines. Biochem Biophys Res Commun. 431:530–534.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zhang J, Zhang H, Deng X, Zhang Y and Xu
K: Baicalin protects AML-12 cells from lipotoxicity via the
suppression of ER stress and TXNIP/NLRP3 inflammasome activation.
Chem Biol Interact. 278:189–196. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Gajaria TK, Patel DK, Devkar RV and
Ramachandran AV: Flavonoid rich extract of Murraya Koenigii
alleviates in-vitro LDL oxidation and oxidized LDL induced
apoptosis in raw 264.7 Murine macrophage cells. J Food Sci Technol.
52:3367–3375. 2015.PubMed/NCBI
|
|
6
|
Kwon EY, Jung UJ, Park T, Yun JW and Choi
MS: Luteolin attenuates hepatic steatosis and insulin resistance
through the interplay between the liver and adipose tissue in mice
with diet-induced obesity. Diabetes. 64:1658–1669. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ye C, Li S, Yao W, Xu L, Qiu Y, Liu Y, Wu
Z and Hou Y: The anti-inflammatory effects of baicalin through
suppression of NLRP3 inflammasome pathway in LPS-challenged piglet
mononuclear phagocytes. Innate Immun. 22:196–204. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Vecchione G, Grasselli E, Cioffi F,
Baldini F, Oliviera PJ, Sardão VA, Cortese K, Lanni A, Voci A,
Portincasa P and Vergani L: The nutraceutic silybin counteracts
excess lipid accumulation and ongoing oxidative stress in an in
vitro model of non-alcoholic fatty liver disease progression. Front
Nutr. 4:422017. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Loguercio C, Andreone P, Brisc C, Brisc
MC, Bugianesi E, Chiaramonte M, Cursaro C, Danila M, de Sio I,
Floreani A, et al: Silybin combined with phosphatidylcholine and
vitamin E in patients with nonalcoholic fatty liver disease: A
randomized controlled trial. Free Radic Biol Med. 52:1658–1665.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wan X, Xu C, Lin Y, Lu C, Li D, Sang J, He
H, Liu X, Li Y and Yu C: Uric acid regulates hepatic steatosis and
insulin resistance through the NLRP3 inflammasome-dependent
mechanism. J Hepatol. 64:925–932. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Schroder K, Zhou R and Tschopp J: The
NLRP3 inflammasome: A sensor for metabolic danger? Science.
327:296–300. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Cai C, Zhu X, Li P, Li J, Gong J, Shen W
and He K: NLRP3 deletion inhibits the non-alcoholic steatohepatitis
development and inflammation in Kupffer cells induced by palmitic
acid. Inflammation. 40:1875–1883. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Shirasuna K, Takano H, Seno K, Ohtsu A,
Karasawa T, Takahashi M, Ohkuchi A, Suzuki H, Matsubara S, Iwata H
and Kuwayama T: Palmitic acid induces interleukin-1β secretion via
NLRP3 inflammasomes and inflammatory responses through ROS
production in human placental cells. J Reprod Immunol. 116:104–112.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wu J, Xu X, Li Y, Kou J, Huang F, Liu B
and Liu K: Quercetin, luteolin and epigallocatechin gallate
alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with
regulation of AMPK in endothelial cells. Eur J Pharmacol.
745:59–68. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wang W, Wang C, Ding XQ, Pan Y, Gu TT,
Wang MX, Liu YL, Wang FM, Wang SJ and Kong LD: Quercetin and
allopurinol reduce liver thioredoxin-interacting protein to
alleviate inflammation and lipid accumulation in diabetic rats. Br
J Pharmacol. 169:1352–1371. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Li Y, Yang X, He Y, Wang W, Zhang J, Zhang
W, Jing T, Wang B and Lin R: Negative regulation of NLRP3
inflammasome by SIRT1 in vascular endothelial cells. Immunobiology.
222:552–561. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Du X, Yang Y, Xu C, Peng Z, Zhang M, Lei
L, Gao W, Dong Y, Shi Z, Sun X, et al: Upregulation of miR-181a
impairs hepatic glucose and lipid homeostasis. Oncotarget.
8:91362–91378. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Fu Y, Wang Y, Du L, Xu C, Cao J, Fan T,
Liu J, Su X, Fan S, Liu Q and Fan F: Resveratrol inhibits ionising
irradiation-induced inflammation in MSCs by activating SIRT1 and
limiting NLRP-3 inflammasome activation. Int J Mol Sci.
14:14105–14118. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Li Y, Wang P, Yang X, Wang W, Zhang J, He
Y, Zhang W, Jing T, Wang B and Lin R: SIRT1 inhibits inflammatory
response partly through regulation of NLRP3 inflammasome in
vascular endothelial cells. Mol Immunol. 77:148–156. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kim MY, Lim JH, Youn HH, Hong YA, Yang KS,
Park HS, Chung S, Ko SH, Shin SJ, Choi BS, et al: Resveratrol
prevents renal lipotoxicity and inhibits mesangial cell
glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in
db/db mice. Diabetologia. 56:204–217. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Song Y, Li N, Gu J, Fu S, Peng Z, Zhao C,
Zhang Y, Li X, Wang Z, Li X and Liu G: β-Hydroxybutyrate induces
bovine hepatocyte apoptosis via an ROS-p38 signaling pathway. J
Dairy Sci. 99:9184–9198. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Du X, Chen L, Huang D, Peng Z, Zhao C,
Zhang Y, Zhu Y, Wang Z, Li X and Liu G: Elevated apoptosis in the
liver of dairy cows with ketosis. Cell Physiol Biochem. 43:568–578.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Musso G, Cassader M and Gambino R:
Non-alcoholic steatohepatitis: Emerging molecular targets and
therapeutic strategies. Nat Rev Drug Discov. 15:249–274. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
de Alwis NM and Day CP: Non-alcoholic
fatty liver disease: The mist gradually clears. J Hepatol. 48 Suppl
1:S104–S112. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hardy T, Anstee QM and Day CP:
Nonalcoholic fatty liver disease: New treatments. Curr Opin
Gastroenterol. 31:175–183. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Michel Anto N, Colberg C, Buscher K,
Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K,
Marchini T, et al: Inflammatory pathways regulated by
tumor-necrosis receptor associated factor 1 protect from metabolic
consequences in diet-induced obesity. Circ Res. 122:693–700. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Vogt BP, Souza PL, Minicucci MF, Martin
LC, Barretti P and Caramori JT: Metabolic syndrome criteria as
predictors of insulin resistance, inflammation and mortality in
chronic hemodialysis patients. Metab Syndr Relat Disord.
12:443–449. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Vandanmagsar B, Youm YH, Ravussin A,
Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM and Dixit
VD: The NLRP3 inflammasome instigates obesity-induced inflammation
and insulin resistance. Nat Med. 17:179–188. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mridha AR, Wree A, Robertson AAB, Yeh MM,
Johnson CD, Van Rooyen DM, Haczeyni F, Teoh NC, Savard C, Ioannou
GN, et al: NLRP3 inflammasome blockade reduces liver inflammation
and fibrosis in experimental NASH in mice. J Hepatol. 66:1037–1046.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Van De Wier B, Koek GH, Bast A and Haenen
GR: The potential of flavonoids in the treatment of non-alcoholic
fatty liver disease. Crit Rev Food Sci Nutr. 57:834–855. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Sun X, Yuan X, Chen L, Wang T, Wang Z, Sun
G, Li X, Li X and Liu G: Histamine induces bovine rumen epithelial
cell inflammatory response via NF-κB pathway. Cell Physiol Biochem.
42:1109–1119. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhang N, Yang Z, Xiang SZ, Jin YG, Wei WY,
Bian ZY, Deng W and Tang QZ: Nobiletin attenuates cardiac
dysfunction, oxidative stress, and inflammatory in streptozotocin:
Induced diabetic cardiomyopathy. Mol Cell Biochem. 417:87–96. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
He Z, Li X, Chen H, He K, Liu Y and Gong J
and Gong J: Nobiletin attenuates
lipopolysaccharide/D-galactosamineinduced liver injury in mice by
activating the Nrf2 antioxidant pathway and subsequently inhibiting
NF-κB-mediated cytokine production. Mol Med Rep. 14:5595–5600.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Purushotham A, Schug TT, Xu Q, Surapureddi
S, Guo X and Li X: Hepatocyte-specific deletion of SIRT1 alters
fatty acid metabolism and results in hepatic steatosis and
inflammation. Cell Metab. 9:327–338. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Li Y, Xu S, Giles A, Nakamura K, Lee JW,
Hou X, Donmez G, Li J, Luo Z, Walsh K, et al: Hepatic
overexpression of SIRT1 in mice attenuates endoplasmic reticulum
stress and insulin resistance in the liver. FASEB J. 25:1664–1679.
2011. View Article : Google Scholar : PubMed/NCBI
|
