Journal Articles

Review Open Access

Mangiferin: An effective therapeutic agent against several disorders (Review)

Suya Du, Huirong Liu, Tiantian Lei, Xiaofang Xie, Hailian Wang, Xia He, Rongsheng Tong, Yi Wang

Pages: 4775-4786 Published online on: 02 October 2018
Review Open Access

Peripheral artery disease and osteoporosis: Not only age‑related (Review)

Agostino Gaudio, Anastasia Xourafa, Rosario Rapisarda, Pietro Castellino , Salvatore Santo Signorelli

Pages: 4787-4792 Published online on: 27 September 2018
Review Open Access

Characteristics of Nur77 and its ligands as potential anticancer compounds (Review)

Lingjuan Wu, Liqun Chen

Pages: 4793-4801 Published online on: 27 September 2018
Article Open Access

Intermittent fasting increases SOD2 and catalase immunoreactivities in the hippocampus but does not protect from neuronal death following transient ischemia in gerbils

Ji Hyeon Ahn, Yoohun Noh, Bich Na Shin, Sung‑Su Kim, Joon Ha Park, Tae‑Kyeong Lee, Minah Song, Hyunjung Kim, Jae‑Chul Lee, Jun‑Hwan Yong, Il Jun Kang, Yun Lyul Lee, Moo‑Ho Won, Jong Dai Kim

Pages: 4802-4812 Published online on: 21 September 2018
Article Open Access

(‑)Epigallocatechin‑3‑gallate attenuates anesthesia‑induced memory deficit in young mice via modulation of nitric oxide expression

Li Ding, Xiang Gao, Jianlei Hu, Shenghui Yu

Pages: 4813-4820 Published online on: 10 October 2018
Article Open Access

Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation

Zhengxin Huang, Yingfeng Liu, Xianping Huang

Pages: 4821-4830 Published online on: 10 October 2018
Article Open Access

Inhibition of microRNA‑939 suppresses the development of human non‑small cell lung cancer via the upregulation of tissue inhibitor of metalloproteinases 2

Aidong Chen, Shengping Liu, Xiaohu Lu, Lei Wei, Yijiang Chen

Pages: 4831-4838 Published online on: 20 September 2018
Article Open Access
Article Open Access

miR‑3666 suppresses cellular proliferation and invasion in colorectal cancer by targeting SATB2

Daqing Yang, Rizeng Li, Jianfu Xia, Wencai Li, Hong Zhou

Pages: 4847-4854 Published online on: 09 October 2018
Article Open Access

S100B regulates inflammatory response during osteoarthritis via fibroblast growth factor receptor 1 signaling

Lifan Zhu, Zhen Weng, Pengcheng Shen, Jianxin Zhou, Jincai Zeng, Fengbiao Weng, Xiaojian Zhang, Huilin Yang

Pages: 4855-4864 Published online on: 01 October 2018
Article Open Access

Profiling cytochrome P450 family 4 gene expression in human hepatocellular carcinoma

Hyuk Soo Eun, Sang Yeon Cho, Byung Seok Lee, In‑Ock Seong, Kyung‑Hee Kim

Pages: 4865-4876 Published online on: 01 October 2018
Article Open Access

Knockdown of BRCC3 exerts an anti‑tumor effect on cervical cancer in vitro

Feifang Zhang, Qun Zhou

Pages: 4886-4894 Published online on: 26 September 2018
Article Open Access

Oral microbial flora of patients with Sicca syndrome

Shuang Zhou, Ye Cai, Min Wang, Wei‑Dong Yang, Ning Duan

Pages: 4895-4903 Published online on: 27 September 2018
Article Open Access

A family with hypothyroidism caused by fatty acid synthase and apolipoprotein B receptor mutations

Jianhua Sun, Lizhi Sun, Weijie Chen, Xiao Yin, Yong Lu, Qiang Jiang

Pages: 4904-4912 Published online on: 20 September 2018
Article Open Access

Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP‑induced Parkinson's disease models in vitro and in vivo

Hucheng Chen, Jiyu Xu, Yuan Lv, Ping He, Chunyan Liu, Jie Jiao, Shiwei Li, Xuhua Mao, Xue Xue

Pages: 4913-4921 Published online on: 25 September 2018
Article Open Access

Electroacupuncture inhibits sodium nitroprusside‑mediated chondrocyte apoptosis through the mitochondrial pathway

Jie Lin, Guangwen Wu, Jun Chen, Changlong Fu, Xiue Hong, Li Li, Xianxiang Liu, Mingxia Wu

Pages: 4922-4930 Published online on: 20 September 2018
Article Open Access

Examining the key genes and pathways in hepatocellular carcinoma development from hepatitis B virus‑positive cirrhosis

Qi‑Feng Chen, Jin‑Guo Xia, Wang Li, Lu‑Jun Shen, Tao Huang, Peihong Wu

Pages: 4940-4950 Published online on: 19 September 2018
Article Open Access

MrgX2‑mediated internalization of LL‑37 and degranulation of human LAD2 mast cells

Taisuke Murakami, Kaori Suzuki, Francois Niyonsaba, Hiroyuki Tada, Johannes Reich, Hiroshi Tamura, Isao Nagaoka

Pages: 4951-4959 Published online on: 02 October 2018
Article Open Access

Expression of long non‑coding RNA and mRNA in the hippocampus of mice with type 2 diabetes

Li‑Ya Ci, De‑Shan Liu, Jing‑Qing Yang, Yu Zhao Liu, Chang Ling Li, Xi Zhang, Chun Mei Ma, Rui Ting Hu

Pages: 4960-4968 Published online on: 21 September 2018
Article Open Access

Mechanism of HN‑3 cell apoptosis induced by carboplatin: Combination of mitochondrial pathway associated with Ca2+ and the nucleus pathways

Bo Shen, Wenjing Mao, Jin‑Chul Ahn, Phil‑Sang Chung, Peijie He

Pages: 4978-4986 Published online on: 24 September 2018
Article Open Access

The possible association between AQP9 in the intestinal epithelium and acute liver injury‑induced intestinal epithelium damage

Tianxin Xiang, Shanfei Ge, Jiangxiong Wen, Junfeng Xie, Lixia Yang, Xiaoping Wu, Na Cheng

Pages: 4987-4993 Published online on: 10 October 2018
Article Open Access

Upregulated miR‑203a‑3p and its potential molecular mechanism in breast cancer: A study based on bioinformatics analyses and a comprehensive meta‑analysis

Kai‑Teng Cai, Cai‑Xia Feng, Jin‑Che Zhao, Rong‑Quan He, Jie Ma, Jin‑Cai Zhong

Pages: 4994-5008 Published online on: 10 October 2018
Article Open Access

Hydrogen molecules (H2) improve perfusion recovery via antioxidant effects in experimental peripheral arterial disease

Jinrong Fu, Jinjing Zou, Cheng Chen, Hongying Li, Lei Wang, Yanli Zhou

Pages: 5009-5015 Published online on: 10 October 2018
Article Open Access

Compound pathogenic mutation in the USH2A gene in Chinese RP families detected by whole‑exome sequencing

Yue‑Chuan Fu, Na Chen, Zi‑Long Qiu, Lin Liu, Jie Shen

Pages: 5016-5022 Published online on: 02 October 2018
Article Open Access

Abnormal expression of miR‑133a in patients with acute myocardial infarction following radical surgery for gastric cancer and the underlying mechanism

Jing Yu, Xufen Cao, Ye Zheng, Liqiu Yan, Jiawang Wang

Pages: 5023-5029 Published online on: 10 October 2018
Article Open Access

Berberine promotes nerve regeneration through IGFR‑mediated JNK‑AKT signal pathway

Hai‑Na Zhang, Ya‑Juan Sun, Huai‑Qiang He, Hong‑Yan Li, Qiu‑Li Xue, Zhong‑Min Liu, Guang‑Meng Xu, Li‑Hua Dong

Pages: 5030-5036 Published online on: 24 September 2018
Article Open Access

Ketamine destabilizes growth of dendritic spines in developing hippocampal neurons in vitro via a Rho‑dependent mechanism

Sufang Jiang, Zimiao Hao, Xuze Li, Lijun Bo, Rui Zhang, Ying Wang, Xiaofeng Duan, Rongtian Kang, Lining Huang

Pages: 5037-5043 Published online on: 02 October 2018
Article Open Access

Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro

Ganming Deng, Kaiqun Li, Siwei Chen, Peisheng Chen, Haonan Zheng, Bin Yu, Kairui Zhang

Pages: 5044-5052 Published online on: 10 October 2018
Article Open Access

Co-existence of endometriosis with 13 non-gynecological co-morbidities: Mutation analysis by whole exome sequencing

Charoula Matalliotaki, Michail Matalliotakis, Maria I. Zervou, Alexandra Trivli, Ioannis Matalliotakis, George Mavromatidis, Demetrios A. Spandidos, Hans M. Albertsen, Rakesh Chettier, Kenneth Ward, George N. Goulielmos

Pages: 5053-5057 Published online on: 01 October 2018
Article Open Access

Microarray analysis reveals long non‑coding RNA SOX2OT as a novel candidate regulator in diabetic nephropathy

Xiaoxue Zhang, Jin Shang, Xiaoyang Wang, Genyang Cheng, Yumin Jiang, Dong Liu, Jing Xiao, Zhanzheng Zhao

Pages: 5058-5068 Published online on: 04 October 2018
Article Open Access

Mining the potential therapeutic targets for coronary artery disease by bioinformatics analysis

Wendong Wang, Zhiwei Xu, Xiaobo Zhu, Xiaotong Chang

Pages: 5069-5075 Published online on: 10 October 2018
Article

Biomarkers associated with binaprofen‑induced liver injury

Qiuping Guo, Jianmin Guo, Guiying Chen, Zhong Han, Baiquan Xiao, Ruomin Jin, Chun Liang, Wei Yang

Pages: 5076-5086 Published online on: 10 October 2018
Article

ROR1 is highly expressed in circulating tumor cells and promotes invasion of pancreatic cancer

Gui‑Li Xu, Jian Shen, Yun‑Hua Xu, Wan‑Sheng Wang, Cai‑Fang Ni

Pages: 5087-5094 Published online on: 20 September 2018
Article

Whole exome sequencing identification of a novel insertion mutation in the phospholipase C ε‑1 gene in a family with steroid resistant inherited nephrotic syndrome

Jamil Amjad Hashmi, Ramziah Ahmed Safar, Sibtain Afzal, Alia M. Albalawi, Feroz Abdu‑Samad, Zafar Iqbal, Sulman Basit

Pages: 5095-5100 Published online on: 02 October 2018
Article

CXCL12 modulates the radiosensitivity of cervical cancer by regulating CD44

Zhichao Fu, Pei Zhang, Huachun Luo, Huijuan Huang, Fengmei Wang

Pages: 5101-5108 Published online on: 12 October 2018
Article

Construction of an miRNA‑gene regulatory network in colorectal cancer through integrated analysis of mRNA and miRNA microarrays

Jun Hu, Xin Yue, Jianzhong Liu, Dalu Kong

Pages: 5109-5116 Published online on: 24 September 2018
Article

Endoplasmic reticulum stress associated apoptosis as a novel mechanism in indoxyl sulfate‑induced cardiomyocyte toxicity

Xiao Tan, Xue‑Sen Cao, Pan Zhang, Fang‑Fang Xiang, Jie Teng, Jian‑Zhou Zou, Xiao‑Qiang Ding

Pages: 5117-5122 Published online on: 20 September 2018
Article

Identification of miRNA and mRNA expression profiles by PCR microarray in hepatitis B virus‑associated hepatocellular carcinoma

Xiong‑Wei Cui, Zhi‑Ling Qian, Cong Li, Shi‑Chang Cui

Pages: 5123-5132 Published online on: 27 September 2018
Article

Salmonella‑induced miR‑155 enhances necroptotic death in macrophage cells via targeting RIP1/3

Young‑Tae Ro, Guk‑Heui Jo, Sun‑Ah Jung, Eunjoo H. Lee, Jongdae Shin, Joon H. Lee

Pages: 5133-5140 Published online on: 01 October 2018
Article

EP4 knockdown alleviates glomerulosclerosis through Smad and MAPK pathways in mesangial cells

Yingjie Cao, Tianyi Pan, Xiaolan Chen, Jianhua Wu, Naifeng Guo, Bicheng Wang

Pages: 5141-5150 Published online on: 12 October 2018
Article

Synergistic effects of vemurafenib and fingolimod (FTY720) in vemurafenib‑resistant melanoma cell lines

Tomoko Takahashi, Naoko Abe, Hiroyuki Kanoh, Yoshiko Banno, Mariko Seishima

Pages: 5151-5158 Published online on: 08 October 2018
Article

Mitochondrial tRNAIle A4317G mutation may be associated with hearing impairment in a Han Chinese family

Yong Cui, Duan‑Jun He

Pages: 5159-5165 Published online on: 27 September 2018
Article

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Kyu‑Hee Hwang, Ji‑Hee Kim, Eun Young Park, Seung‑Kuy Cha

Pages: 5166-5172 Published online on: 08 October 2018
Article

Long non‑coding RNA CASC2 inhibits progression and predicts favorable prognosis in epithelial ovarian cancer

Zhuowei Xue, Xiaolu Zhu, Yincheng Teng

Pages: 5173-5181 Published online on: 10 October 2018
Article

Lutein protects human retinal pigment epithelial cells from oxidative stress‑induced cellular senescence

Seon Yeong Chae, Sun Young Park, Geuntae Park

Pages: 5182-5190 Published online on: 08 October 2018
Article

Astragalus root induces ovarian β‑oxidation and suppresses estrogen‑dependent uterine proliferation

Banzragchgarav Orkhon, Kyoko Kobayashi, Batkhuu Javzan, Kenroh Sasaki

Pages: 5198-5206 Published online on: 19 September 2018
Article

Aloe emodin suppresses EGF‑induced neoplastic cell transformation by inhibiting the ERK/MSK1 and AKT/GSK3β signaling pathways

Juan Zhang, Lihua Guo, Quanwu Zhang, Kangdong Liu, Ziming Dong

Pages: 5215-5220 Published online on: 27 September 2018
Article

MicroRNA‑944 targets vascular endothelial growth factor to inhibit cell proliferation and invasion in osteosarcoma

Tingzhen Yan, Shiyong Zhu, Jing Zhang, Gongbiao Lu, Chaoliang Lv, Yanchun Wei, Minghua Luo

Pages: 5221-5228 Published online on: 01 October 2018
Article

Role of endothelin‑1 and its receptors in cerebral vasospasm following subarachnoid hemorrhage

Ya‑Wen Cheng, Wen‑Juan Li, Xiang‑Jun Dou, Rui Jia, Hua Yang, Xin‑Guang Liu, Cang‑Bao Xu, Jing Liu, Yong‑Xiao Cao, Guo‑Gang Luo

Pages: 5229-5236 Published online on: 27 September 2018
Article

Role of JNK signalling pathway and platelet‑lymphocyte aggregates in myocardial ischemia‑reperfusion injury and the cardioprotective effect of ischemic postconditioning in rats

Faxin Ren, Nan Mu, Mingxiao Gao, Jing Sun, Chuanhuan Zhang, Xiaojian Sun, Liudong Li, Jun Li, Tong Liu, Gary Tse, Mei Dong

Pages: 5237-5242 Published online on: 10 October 2018
Article

Effects of polymorphic DNA genes involved in BER and caspase pathways on the clinical outcome of myeloproliferative neoplasms under treatment with hydroxyurea

Ana P. Azevedo, Susana N. Silva, Alice Reichert, Fernando Lima, Esmeraldina Júnior, José Rueff

Pages: 5243-5255 Published online on: 08 October 2018
Article

Suppressing cell growth and inducing apoptosis by inhibiting miR‑23a‑5p in human bladder cancer

Yifan Li, Jing Quan, Xiang Pan, Jingcheng Zhou, Anbang He, Yongqing Lai, Guangchen Zhou

Pages: 5256-5260 Published online on: 02 October 2018
Article

MicroRNA‑339‑5p inhibits cell proliferation of acute myeloid leukaemia by directly targeting SOX4

Xueming Sun, Huaqiang Liu, Tingting Li, Laiying Qin

Pages: 5261-5269 Published online on: 10 October 2018
Article

miR‑124 inhibits cell growth through targeting IQGAP1 in colorectal cancer

Jianyu Fan, Wenjing Zhang, Yanting Wu, Ping Wan, Qiang Guo, Yu Zhang

Pages: 5270-5278 Published online on: 27 September 2018
Article

NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model

Hitomi Fukatsu, Naoki Koide, Saeko Tada‑Oikawa, Kiyora Izuoka, Akihiko Ikegami, Sahoko Ichihara, Tamami Ukaji, Naoko Morita, Yoshikazu Naiki, Takayuki Komatsu, Kazuo Umezawa

Pages: 5279-5285 Published online on: 03 October 2018
Article

LncRNA‑p21 promotes chondrocyte apoptosis in osteoarthritis by acting as a sponge for miR‑451

Luping Tang, Jianbo Ding, Guangju Zhou, Zhihai Liu

Pages: 5295-5301 Published online on: 24 September 2018
Correction Open Access

[Corrigendum] High glucose promotes tumor cell proliferation and migration in lung adenocarcinoma via the RAGE‑NOXs pathway

Yuan‑Fan Liao, Sui Yin, Zi‑Qi Chen, Fan Li, Bo Zhao

Pages: 5302-5302 Published online on: 12 October 2018
Review

Roles of fatty acid metabolism in tumourigenesis: Beyond providing nutrition (Review)

Xiang‑Hua Yu, Xiao‑Hua Ren, Xin‑Hua Liang, Ya‑Ling Tang

Pages: 5307-5316 Published online on: 23 October 2018
Article Open Access

Lentivirus‑mediated microRNA‑26a overexpression in bone mesenchymal stem cells facilitates bone regeneration in bone defects of calvaria in mice

Zhi Liu, Hong Chang, Yihong Hou, Yu Wang, Zhiqiang Zhou, Ming Wang, Zhidong Huang, Bin Yu

Pages: 5317-5326 Published online on: 25 October 2018
Article Open Access

High LIN28A and PLK4 co‑expression is associated with poor prognosis in epithelial ovarian cancer

Yao He, Hui Wang, Meina Yan, Xinxin Yang, Rong Shen, Xiaoge Ni, Xiaokun Chen, Peifang Yang, Miao Chen, Xiaodong Lu, Genbao Shao, Xiaoming Zhou, Qixiang Shao

Pages: 5327-5336 Published online on: 16 October 2018
Article Open Access

Effects of compound 21, a non‑peptide angiotensin II type 2 receptor agonist, on general anesthesia‑induced cerebral injury in neonatal rats

Jun Yong, Li Yan, Jing Wang, Hongmei Xiao, Qingfan Zeng

Pages: 5337-5344 Published online on: 26 October 2018
Article Open Access

Dexamethasone inhibits NF‑кBp65 and HMGB1 expression in the pancreas of rats with severe acute pancreatitis

Shangping Zhao, Jinming Yang, Ting Liu, Juanxian Zeng, Liangliang Mi, Kaimin Xiang

Pages: 5345-5352 Published online on: 25 October 2018
Article Open Access

Pilose antler polypeptide protects against sevoflurane‑mediated neurocyte injury

Shuping Li, Jiaxuan He

Pages: 5353-5360 Published online on: 24 October 2018
Article Open Access

Identification of recurrent and novel mutations by whole‑genome sequencing of colorectal tumors from the Han population in Shanghai, eastern China

Hongfei Teng, Renyuan Gao, Nan Qin, Xun Jiang, Min Ren, Yu Wang, Shouxin Wu, Ning Li, Jiangman Zhao, Huanlong Qin

Pages: 5361-5370 Published online on: 17 October 2018
Article Open Access

Protective effect of polysaccharide peptide on cerebral ischemia‑reperfusion injury in rats

Pengcheng Xing, Ke Ma, Jun Wu, Wei Long, Donglian Wang

Pages: 5371-5378 Published online on: 23 October 2018
Article Open Access

Knockdown of the Hippo transducer YAP reduces proliferation and promotes apoptosis in the Jurkat leukemia cell

Ran Wu, Hui Yang, Jiangbo Wan, Xiaohui Deng, Linjun Chen, Siguo Hao, Liyuan Ma

Pages: 5379-5388 Published online on: 15 October 2018
Article Open Access
Article Open Access

Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages

Zhenyu Qiu, Hongxia Yuan, Na Li, Xinjuan Yang, Xuemei Hu, Fengtai Su, Baiyi Chen

Pages: 5399-5408 Published online on: 22 October 2018
Article Open Access

Nrf2 is a key factor in the reversal effect of curcumin on multidrug resistance in the HCT‑8/5‑Fu human colorectal cancer cell line

Chao Zhang, Lian‑Jun He, Hai‑Zhu Ye, Ding‑Feng Liu, Yi‑Bao Zhu, Dong‑Dong Miao, Sheng‑Peng Zhang, Yun‑Yu Chen, Yuan‑Wei Jia, Jie Shen, Xiao‑Ping Liu

Pages: 5409-5416 Published online on: 24 October 2018
Article Open Access

miR‑27a promotes human breast cancer cell migration by inducing EMT in a FBXW7‑dependent manner

Guobin Jiang, Weiwu Shi, Hongyan Fang, Xiaohua Zhang

Pages: 5417-5426 Published online on: 24 October 2018
Article Open Access

Andrographolide mitigates IL‑1β‑induced human nucleus pulposus cells degeneration through the TLR4/MyD88/NF‑κB signaling pathway

Lilian Zhang, Qi Chen, Haoli Wang, Jian Yang, Sunren Sheng

Pages: 5427-5436 Published online on: 25 October 2018
Article Open Access

Overexpression of long non‑coding RNA n346372 in bladder cancer tissues is associated with a poor prognosis

Anwei Liu, Zhensheng Zhang, Weidong Xu, Shengfei Qin, Meimian Hua, Shuxiong Zeng, Chuanliang Xu

Pages: 5437-5444 Published online on: 25 October 2018
Article Open Access

Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway

Yang Su, Jingxiao Lu, Pian Gong, Xianguo Chen, Chaozhao Liang, Jie Zhang

Pages: 5445-5454 Published online on: 24 October 2018
Article Open Access

Involvement of Beclin‑1 in axonal protection by short‑term hyperglycemia against TNF‑induced optic nerve damage

Kana Sase, Yasushi Kitaoka, Chihiro Tsukahara, Hitoshi Takagi

Pages: 5455-5460 Published online on: 22 October 2018
Article Open Access

FAK regulates epithelial‑mesenchymal transition in adenomyosis

Dexuan Zheng, Hua Duan, Sha Wang, Qian Xu, Lu Gan, Jinjiao Li, Qianjing Dong

Pages: 5461-5472 Published online on: 26 October 2018
Article Open Access

Overexpression of klotho in adipose-derived stem cells protects against UVB-induced photoaging in co-cultured human fibroblasts

Furong Fan, Yufei Li, Yi Liu, Li Shao, Juehua Yu, Ziwei Li

Pages: 5473-5480 Published online on: 25 October 2018
Article Open Access

Overexpression of miR‑146a blocks the effect of LPS on RANKL‑induced osteoclast differentiation

Yingjian Gao, Bo Wang, Conghuan Shen, Weiwei Xin

Pages: 5481-5488 Published online on: 30 October 2018
Article Open Access

miR‑371b‑5p inhibits endothelial cell apoptosis in monocrotaline‑induced pulmonary arterial hypertension via PTEN/PI3K/Akt signaling pathways

Guangfa Zhu, Wenmei Zhang, Yan Liu, Shenghao Wang

Pages: 5489-5501 Published online on: 31 October 2018
Article Open Access

miRNA array analysis of plasma miRNA alterations in rats exposed to a high altitude hypoxic environment

Feng Chen, Ren‑Jie Wang, Guang‑Zong Li, Yi Zhang, Shuo Yu, Ying‑Fu Liu, Xiao‑Yi Chen, Shi‑Ke Hou

Pages: 5502-5510 Published online on: 22 October 2018
Article Open Access

Effects of mimicked acetylated HMGB1 on macrophages and dendritic cells

Xiaohong Chen, Yong Xu, Ping Xiong, Zheng Tan, Feili Gong, Xiaohua Hou, Fang Zheng

Pages: 5527-5535 Published online on: 24 October 2018
Article
Article Open Access

Lentiviral‑mediated inducible silencing of TLR4 attenuates neuropathic pain in a rat model of chronic constriction injury

Yantao Liu, Yan Zhang, Ruirui Pan, Mo Chen, Xiaoqiang Wang, Erliang Kong, Weifeng Yu, Yuming Sun, Feixiang Wu

Pages: 5545-5551 Published online on: 16 October 2018
Article Open Access

UBA2 promotes proliferation of colorectal cancer

Ping He, Xun Sun, Hong‑Jing Cheng, Ya‑Bin Zou, Quan Wang, Chang‑Li Zhou, Wan‑Qi Liu, Yue‑Ming Hao, Xiang‑Wei Meng

Pages: 5552-5562 Published online on: 30 October 2018
Article Open Access

Therapeutic effects of a mesenchymal stem cell‑based insulin‑like growth factor‑1/enhanced green fluorescent protein dual gene sorting system in a myocardial infarction rat model

Subin Jung, Jung‑Hyun Kim, Changwhi Yim, Minhyung Lee, Hyo Jin Kang, Donghoon Choi

Pages: 5563-5571 Published online on: 16 October 2018
Article Open Access

Zeylenone represses the progress of human prostate cancer by downregulating the Wnt/β‑catenin pathway

Shaohua Zeng, Baoyi Zhu, Jun Zeng, Wenqi Wu, Chonghe Jiang

Pages: 5572-5578 Published online on: 17 October 2018
Article Open Access

LASSO‑based Cox‑PH model identifies an 11‑lncRNA signature for prognosis prediction in gastric cancer

Yonghong Zhang, Huamin Li, Wenyong Zhang, Ya Che, Weibing Bai, Guanglin Huang

Pages: 5579-5593 Published online on: 22 October 2018
Article Open Access

Bioinformatics analysis to identify key genes and pathways influencing synovial inflammation in osteoarthritis

Jie Lin, Guangwen Wu, Zhongsheng Zhao, Yanfeng Huang, Jun Chen, Changlong Fu, Jinxia Ye, Xianxiang Liu

Pages: 5594-5602 Published online on: 23 October 2018
Article Open Access

MicroRNA‑181 serves an oncogenic role in breast cancer via the inhibition of SPRY4 Retraction in /10.3892/mmr.2022.12673

Yifu Tian, Xiaodan Fu, Qingling Li, Ying Wang, Dan Fan, Qin Zhou, Weilu Kuang, Liangfang Shen

Pages: 5603-5613 Published online on: 22 October 2018
Article Open Access

lncRNA FEZF1‑AS1 contributes to cell proliferation, migration and invasion by sponging miR‑4443 in hepatocellular carcinoma

Jianhua Gong, Junyi Wang, Tianpin Liu, Jun Hu, Jun Zheng

Pages: 5614-5620 Published online on: 24 October 2018
Article Open Access

Examination of the expression and prognostic significance of DLGAPs in gastric cancer using the TCGA database and bioinformatic analysis

Jiaxin Liu, Zhao Liu, Xiaozhi Zhang, Tuotuo Gong, Demao Yao

Pages: 5621-5629 Published online on: 23 October 2018
Article Open Access

Exploration of the diagnostic value and molecular mechanism of miR‑1 in prostate cancer: A study based on meta‑analyses and bioinformatics

Zu‑Cheng Xie, Jia‑Cheng Huang, Li‑Jie Zhang, Bin‑Liang Gan, Dong‑Yue Wen, Gang Chen, Sheng‑Hua Li, Hai‑Biao Yan

Pages: 5630-5646 Published online on: 25 October 2018
Article Open Access

Expression of claudin‑11 in a rat model of varicocele and its effects on the blood‑testis barrier

Jiangang Pan, Zhirong Zhu, Gang Xu, Lili Niu, Lihang Yu, Zhengang Luo, Jiajun Yan

Pages: 5647-5651 Published online on: 26 October 2018
Article Open Access

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis in mice

Huan Zhou, Hui‑Jing Zhang, Lin Guan, Yi‑Ning Zhang, Yue Li, Ming‑Jun Sun

Pages: 5652-5662 Published online on: 30 October 2018
Article

Parkin deficiency elevates hepatic ischemia/reperfusion injury accompanying decreased mitochondrial autophagy, increased apoptosis, impaired DNA damage repair and altered cell cycle distribution

Xiao‑Jie Ning, Xiong Yan, Yan‑Feng Wang, Ren Wang, Xiao‑Li Fan, Zi‑Biao Zhong, Qi‑Fa Ye

Pages: 5663-5668 Published online on: 29 October 2018
Article Open Access
Article

miR‑23b‑3p promotes the apoptosis and inhibits the proliferation and invasion of osteosarcoma cells by targeting SIX1

Hua Liu, Wei Wei, Xiaojian Wang, Xiaojun Guan, Qingqing Chen, Zhongjin Pu, Xudong Xu, Aichun Wei

Pages: 5683-5692 Published online on: 30 October 2018
Article

Inhibitory effect of tranilast on the myofibroblast differentiation of rat mesenchymal stem cells induced by transforming growth factor‑β1 in vitro

Wenxian Tang, Yuejuan Zhang, Lin Tang, Jun Zhang, Lei Xiong, Baohe Wang

Pages: 5693-5700 Published online on: 24 October 2018
Article

Identification of the inhibitory activity of walnut extract on the E3 ligase Syvn1

Hidetoshi Fujita, Satoko Aratani, Naoko Yagishita, Kusuki Nishioka, Toshihiro Nakajima

Pages: 5701-5708 Published online on: 23 October 2018
Article

Comparison of human lumbar disc pressure characteristics during simulated spinal manipulation vs. spinal mobilization

Fei Wang, Jun Zhang, Wei Feng, Qiang Liu, Xianwen Yang, Hui Zhang, Lei Han, Yaqing Min, Ping Zhao

Pages: 5709-5716 Published online on: 25 October 2018
Article

Differentiation of human amniotic epithelial cells into osteoblasts is induced by mechanical stretch via the Wnt/β‑catenin signalling pathway

Fujun Luan, Kunlong Ma, Jia Mao, Fan Yang, Minghua Zhang, Hexu Luan

Pages: 5717-5725 Published online on: 22 October 2018
Article

Hepatitis B core antigen regulates dendritic cell proliferation and apoptosis through regulation of PKC/NF‑κB signaling pathway

Lan Liu, Yanxin Huang, Kaili Zhang, Shupeng Song, Shuangxing Li, Yongguo Li, Yinghua Lan

Pages: 5726-5732 Published online on: 26 October 2018
Article

Helicobacter pylori infection enhances heparanase leading to cell proliferation via mitogen‑activated protein kinase signalling in human gastric cancer cells

Liping Liu, Yongxun Zhao, Guangrui Fan, Tiankui Shuai, Bin Li, Yumin Li

Pages: 5733-5741 Published online on: 15 October 2018
Article

Downregulation of growth arrest‑specific transcript 5 alleviates palmitic acid‑induced myocardial inflammatory injury through the miR‑26a/HMGB1/NF‑κB axis

Qingxiong Yue, Cuiting Zhao, Yonghuai Wang, Lanting Zhao, Qing Zhu, Guangyuan Li, Nan Wu, Dalin Jia, Chunyan Ma

Pages: 5742-5750 Published online on: 25 October 2018
Article

Isolation and characterization of stem cells from differentially degenerated human lumbar zygapophyseal articular cartilage

Liang Xiao, Shujuan Xu, Xiao Wang, Zhongxing Jin, Jing Wang, Bijing Yang, Hongguang Xu

Pages: 5751-5759 Published online on: 25 October 2018
Case Report

Two novel pathogenic variants of L1CAM gene in two fetuses with isolated X‑linked hydrocephaly: A case report

Bobo Xie, Jingsi Luo, Yaqin Lei, Qi Yang, Mengting Li, Shang Yi, Shiyu Luo, Jin Wang, Zailong Qin, Zuojian Yang, Hongwei Wei, Xin Fan

Pages: 5760-5764 Published online on: 24 October 2018
Article

Activator protein‑1 is a novel regulator of mesencephalic astrocyte‑derived neurotrophic factor transcription

Chang‑Hui Wang, Tong‑Cui Jiang, Wei‑Min Qiang, Li Zhang, Li‑Jie Feng, Yu‑Jun Shen, Yu‑Xian Shen

Pages: 5765-5774 Published online on: 26 October 2018
Article

Long non‑coding RNA DILC is involved in sepsis by modulating the signaling pathway of the interleukin‑6/signal transducer and activator of transcription 3/Toll‑like receptor 4 axis

Weiping Huang, Linqiang Huang, Miaoyun Wen, Ming Fang, Yiyu Deng, Hongke Zeng

Pages: 5775-5783 Published online on: 16 October 2018
Article

Apelin‑13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high‑fat diet

Meng Li, Huijuan Fang, Jian Hu

Pages: 5784-5790 Published online on: 29 October 2018
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Long noncoding RNA TUG1 promotes renal cell carcinoma cell proliferation, migration and invasion by downregulating microRNA‑196a

Yang Yang, De‑Ming Sun, Jun‑Feng Yu, Man Zhang, Cheng Yi, Rui Yang, Bao‑Hua Dan, Ai‑Jun Li

Pages: 5791-5798 Published online on: 29 October 2018
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Downregulation of microRNA‑30a in bronchoalveolar lavage fluid from idiopathic pulmonary fibrosis patients

Bao Liu, Tingshu Jiang, Xingang Hu, Zhida Liu, Liming Zhao, Hongmei Liu, Zhaihua Liu, Lijun Ma

Pages: 5799-5806 Published online on: 18 October 2018
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MicroRNA‑93‑5p promotes the progression of human retinoblastoma by regulating the PTEN/PI3K/AKT signaling pathway

Yongliang Cao, Fei Xia, Ping Wang, Meng Gao

Pages: 5807-5814 Published online on: 23 October 2018
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Nobiletin alleviates palmitic acid‑induced NLRP3 inflammasome activation in a sirtuin 1‑dependent manner in AML‑12 cells

Zhicheng Peng, Xiaobing Li, Dongmei Xing, Xiliang Du, Zhe Wang, Guowen Liu, Xinwei Li

Pages: 5815-5822 Published online on: 31 October 2018
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A multiplex ligation‑dependent probe amplification‑based next‑generation sequencing approach for the detection of copy number variations in the human genome

Yongchen Yang, Chaoran Xia, Zaiwei Zhou, Dongkai Wei, Kangping Xu, Jia Jia, Wuhen Xu, Hong Zhang

Pages: 5823-5833 Published online on: 24 October 2018
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Long term exposure to γ‑rays induces radioresistance and enhances the migration ability of bladder cancer cells

Guangmin Mao, Ye Yao, Zhaolu Kong

Pages: 5834-5840 Published online on: 26 October 2018
Journal Cover

December-2018
Volume 18 Issue 6

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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