|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Dai XY, Zhuang LH, Wang DD, Zhou TY, Chang
LL, Gai RH, Zhu DF, Yang B, Zhu H and He QJ: Nuclear translocation
and activation of YAP by hypoxia contributes to the chemoresistance
of SN38 in hepatocellular carcinoma cells. Oncotarget. 7:6933–6947.
2016.PubMed/NCBI
|
|
3
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Hashemi M, Hoshyar R, Ande SR, Chen QM,
Solomon C, Zuse A and Naderi M: Mevalonate cascade and its
regulation in cholesterol metabolism in different tissue in health
and disease. Curr Mol Pharmacol. 10:13–26. 2016. View Article : Google Scholar
|
|
5
|
Gabor KA and Fessler MB: Roles of the
mevalonate pathway and cholesterol trafficking in pulmonary host
defense. Curr Mol Pharmacol. 10:27–45. 2016. View Article : Google Scholar
|
|
6
|
Hashimoto A, Oikawa T, Hashimoto S, Sugino
H, Yoshikawa A, Otsuka Y, Handa H, Onodera Y, Nam JM, Oneyama C, et
al: P53- and mevalonate pathway-driven malignancies require Arf6
for metastasis and drug resistance. J Cell Biol. 213:81–95. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Zahra Bathaie S, Ashrafi M, Azizian M and
Tamanoi F: Mevalonate Pathway and Human Cancers. Curr Mol
Pharmacol. 10:77–85. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Chushi L, Wei W, Kangkang X, Yongzeng F,
Ning X and Xiaolei C: HMGCR is up-regulated in gastric cancer and
promotes the growth and migration of the cancer cells. Gene.
587:42–47. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Mukherjee M, Basu Ball W and Das PK:
Leishmania donovani activates SREBP2 to modulate macrophage
membrane cholesterol and mitochondrial oxidants for establishment
of infection. Int J Biochem Cell Biol. 55:196–208. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Cao J, Wang J, Qi W, Miao HH, Wang J, Ge
L, DeBose-Boyd RA, Tang JJ, Li BL and Song BL: Ufd1 is a cofactor
of gp78 and plays a key role in cholesterol metabolism by
regulating the stability of HMG-CoA reductase. Cell Metab.
6:115–128. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Singh R, Yadav V, Kumar S and Saini N:
MicroRNA-195 inhibits proliferation, invasion and metastasis in
breast cancer cells by targeting FASN HMGCR, ACACA and CYP27B1. Sci
Rep. 5:174542015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Richter K and Buchner J: Hsp90: Twist and
fold. Cell. 127:251–253. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Sawai A, Chandarlapaty S, Greulich H,
Gonen M, Ye Q, Arteaga CL, Sellers W, Rosen N and Solit DB:
Inhibition of Hsp90 down-regulates mutant epidermal growth factor
receptor (EGFR) expression and sensitizes EGFR mutant tumors to
paclitaxel. Cancer Res. 68:589–596. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Citri A, Gan J, Mosesson Y, Vereb G,
Szollosi J and Yarden Y: Hsp90 restrains ErbB-2/HER2 signalling by
limiting heterodimer formation. EMBO Rep. 5:1165–1170. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Sato S, Fujita N and Tsuruo T: Modulation
of Akt kinase activity by binding to Hsp90. Proc Natl Acad Sci USA.
97:10832–10837. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Minet E, Mottet D, Michel G, Roland I,
Raes M, Remacle J and Michiels C: Hypoxia-induced activation of
HIF-1: Role of HIF-1alpha-Hsp90 interaction. FEBS Lett.
460:251–256. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lee YJ, Curetty L, Hou ZZ, Kim SH, Kim JH
and Corry PM: Effect of pH on quercetin-induced suppression of heat
shock gene expression and thermotolerance development in HT-29
cells. Biochem Biophys Res Commun. 186:1121–1128. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhou CC, Yang F, Yuan SX, Ma JZ, Liu F,
Yuan JH, Bi FR, Lin KY, Yin JH, Cao GW, et al: Systemic genome
screening identifies the outcome associated focal loss of long
noncoding RNA PRAL in hepatocellular carcinoma. Hepatology.
63:850–863. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhao S, Li H, Jiang C, Ma T, Wu C, Huo Q
and Liu H: 17-Demethoxy-reblastatin, an Hsp90 inhibitor, induces
mitochondria-mediated apoptosis through downregulation of Mcl-1 in
human hepatocellular carcinoma cells. J Bioenerg Biomembr.
47:373–381. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)). Methods. 25402–408. (25)2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cai Z, Qian ZY, Jiang H, Ma N, Li Z, Liu
LY, Ren XX, Shang YR, Wang JJ, Li JJ, et al: HPCL3s promotes
metastasis of hepatocellular carcinoma by activating β-catenin/TCF
signaling. Cancer Res. 78:2536–2549. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang C, Zhang Y, Guo K, Wang N, Jin H, Liu
Y and Qin W: Heat shock proteins in hepatocellular carcinoma:
Molecular mechanism and therapeutic potential. Int J Cancer.
138:1824–1834. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Liu X, Chen S, Tu J, Cai W and Xu Q: HSP90
inhibits apoptosis and promotes growth by regulating HIF-1alpha
abundance in hepatocellular carcinoma. Int J Mol Med. 37:825–835.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Neuzillet C, Tijeras-Raballand A, de
Mestier L, Cros J, Faivre S and Raymond E: MEK in cancer and cancer
therapy. Pharmacol Ther. 141:160–171. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Cooper LC, Prinsloo E, Edkins AL and
Blatch GL: Hsp90alpha/beta associates with the
GSK3beta/axin1/phospho-beta-catenin complex in the human MCF-7
epithelial breast cancer model. Biochem Biophys Res Commun.
413:550–554. 2011. View Article : Google Scholar : PubMed/NCBI
|
