|
1
|
Hayden FG and Gwaltney JMJ: Viral
infections. In textbook of respiratory medicine. Murray JF and
Nadel JA: WB. Saunders Co.; Philadelphia: pp. 977–1035. 1994
|
|
2
|
Peiris JS, Yu WC, Leung CW, Cheung CY, Ng
WF, Nicholls JM, Ng TK, Chan KH, Lai ST, Lim WL, et al:
Re-emergence of fatal human influenza A subtype H5N1 disease.
Lancet. 363:617–619. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kash JC, Tumpey TM, Proll SC, Carter V,
Perwitasari O, Thomas MJ, Basler CF, Palese P, Taubenberger JK,
García-Sastre A, et al: Genomic analysis of increased host immune
and cell death responses induced by 1918 influenza virus. Nature.
443:578–581. 2006.PubMed/NCBI
|
|
4
|
Hayden FG and de Jong MD: Emerging
influenza antiviral resistance threats. J Infect Dis. 203:6–10.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hai R, Schmolke M, Leyva-Grado VH,
Thangavel RR, Margine I, Jaffe EL, Krammer F, Solórzano A,
García-Sastre A, Palese P and Bouvier NM: Influenza A(H7N9) virus
gains neuraminidase inhibitor resistance without loss of in vivo
virulence or transmissibility. Nat Commun. 4:28542013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Gamblin SJ and Skehel JJ: Influenza
hemagglutinin and neuraminidase membrane glycoproteins. J Biol
Chem. 285:28403–28409. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Thompson AJ and Locarnini SA: Toll-like
receptors, RIG-I-like RNA helicases and the antiviral innate immune
response. Immunol Cell Biol. 85:435–445. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Fukuyama S and Kawaoka Y: The pathogenesis
of influenza virus infections: The contributions of virus and host
factors. Curr Opin Immunol. 23:481–486. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Conenello GM, Zamarin D, Perrone LA,
Tumpey T and Palese P: A single mutation in the PB1-F2 of H5N1
(HK/97) and 1918 influenza A viruses contributes to increased
virulence. PLoS Pathog. 3:1414–1421. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Högner K, Wolff T, Pleschka S, Plog S,
Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlöhner S,
Lewe-Schlosser P, et al: Macrophage-expressed IFN-β contributes to
apoptotic alveolar epithelial cell injury in severe influenza virus
pneumonia. PLoS Pathog. 9:e10031882013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Hagau N, Slavcovici A, Gonganau DN, Oltean
S, Dirzu DS, Brezoszki ES, Maxim M, Ciuce C, Mlesnite M, Gavrus RL,
et al: Clinical aspects and cytokine response in severe H1N1
influenza A virus infection. Crit Care. 14:R2032010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ludwig S and Planz O: Influenza viruses
and the NF-kappaB signaling pathway-towards a novel concept of
antiviral therapy. Biol Chem. 389:1307–1312. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Pinto R, Herold S, Cakarova L, Hoegner K,
Lohmeyer J, Planz O and Pleschka S: Inhibition of influenza
virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both
virus titers and cytokine expression simultaneously in vitro and in
vivo. Antiviral Res. 92:45–56. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ehrhardt C, Marjuki H, Wolff T, Nürnberg
B, Planz O, Pleschka S and Ludwig S: Bivalent role of the
phosphatidylinositol-3-kinase (PI3K) during influenza virus
infection and host cell defence. Cell Microbiol. 8:1336–1348. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Marchant D, Singhera GK, Utokaparch S,
Hackett TL, Boyd JH, Luo Z, Si X, Dorscheid DR, McManus BM and
Hegele RG: Toll-like receptor 4-mediated activation of p38
mitogen-activated protein kinase is a determinant of respiratory
virus entry and tropism. J Virol. 84:11359–11373. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Xu Z, Tang M, Li Y, Liu F, Li X and Dai R:
Antioxidant properties of Du-zhong (Eucommia ulmoides Oliv.)
extracts and their effects on color stability and lipid oxidation
of raw pork patties. J Agric Food Chem. 58:7289–7296. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lee MK, Cho SY, Kim DJ, Jang JY, Shin KH,
Park SA, Park EM, Lee JS, Choi MS, Lee JS, et al: Du-zhong
(Eucommia ulmoides Oliv.) cortex water extract alters heme
biosynthesis and erythrocyte antioxidant defense system in
lead-administered rats. J Med Food. 8:86–92. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hussain T, Tan B, Liu G, Oladele OA, Rahu
N, Tossou MC and Yin Y: Health-promoting properties of eucommia
ulmoides: A review. Evid Based Complement Alternat Med.
2016:52029082016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Li L, Yan J, Hu K, Gu J, Wang JJ, Deng XL,
Li H, Jing X, Li ZY, Ye QF, et al: Protective effects of Eucommia
lignans against hypertensive renal injury by inhibiting expression
of aldose reductase. J Ethnopharmacol. 139:454–461. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Reed LJ and Muench H: A simple method of
estimating fifty percent endpoints. American J Epidemiol.
27:493–497. 1938. View Article : Google Scholar
|
|
21
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2ΔΔCT method.
|
|
22
|
Sugiyama M and Kikuchi M: Studies on the
constituents of osmanthus species. VII. Structures of lignan
glycosides from the leaves of osmanthus asiaticus NAKAI. Chem Pharm
Bull. 396:483–485. 1991. View Article : Google Scholar
|
|
23
|
Marjuki H, Gornitzky A, Marathe BM,
Ilyushina NA, Aldridge JR, Desai G, Webby RJ and Webster RG:
Influenza A virus-induced early activation of ERK and PI3K mediates
V-ATPase-dependent intracellular pH change required for fusion.
Cell Microbiol. 13:587–601. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Marjuki H, Alam MI, Ehrhardt C, Wagner R,
Planz O, Klenk HD, Ludwig S and Pleschka S: Membrane accumulation
of influenza A virus hemagglutinin triggers nuclear export of the
viral genome via protein kinase Calpha-mediated activation of ERK
signaling. J Biol Chem. 281:16707–16715. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ludwig S: Targeting cell signalling
pathways to fight the flu: Towards a paradigm change in
anti-influenza therapy. J Antimicrob Chemother. 64:1–4. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hayden FG, Fritz R, Lobo MC, Alvord W,
Strober W and Straus SE: Local and systemic cytokine responses
during experimental human influenza A virus infection. Relation to
symptom formation and host defense. J Clin Invest. 101:643–649.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
de Jong MD, Simmons CP, Thanh TT, Hien VM,
Smith GJ, Chau TN, Hoang DM, Chau NV, Khanh TH, Dong VC, et al:
Fatal outcome of human influenza A (H5N1) is associated with high
viral load and hypercytokinemia. Nat Med. 12:1203–1207. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Parhira S, Yang ZF, Zhu GY, Chen QL, Zhou
BX, Wang YT, Liu L, Bai LP and Jiang ZH: In vitro anti-influenza
virus activities of a new lignan glycoside from the latex of
Calotropis gigantea. PLoS One. 9:e1045442014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mazur I, Wurzer WJ, Ehrhardt C, Pleschka
S, Puthavathana P, Silberzahn T, Wolff T, Planz O and Ludwig S:
Acetylsalicylic acid (ASA) blocks influenza virus propagation via
its NF-kappaB-inhibiting activity. Cell Microbiol. 9:1683–1694.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kumar N, Xin ZT and Liang Y, Ly H and
Liang Y: NF-kappaB signaling differentially regulates influenza
virus RNA synthesis. J Virol. 82:9880–9889. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Shin YK, Liu Q, Tikoo SK, Babiuk LA and
Zhou Y: Effect of the phosphatidylinositol 3-kinase/Akt pathway on
influenza A virus propagation. J Gen Virol. 88:942–950. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Nencioni L, De Chiara G, Sgarbanti R,
Amatore D, Aquilano K, Marcocci ME, Serafino A, Torcia M, Cozzolino
F, Ciriolo MR, et al: Bcl-2 expression and p38MAPK activity in
cells infected with influenza A virus: Impact on virally induced
apoptosis and viral replication. J Biol Chem. 284:16004–16015.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Guan W, Li J, Chen Q, Jiang Z, Zhang R,
Wang X, Yang Z and Pan X: Pterodontic acid isolated from laggera
pterodonta inhibits viral replication and inflammation induced by
influenza A virus. Molecules. 22:E17382017. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Bauer TT, Ewig S, Rodloff AC and Müller
EE: Acute respiratory distress syndrome and pneumonia: A
comprehensive review of clinical data. Clin Infect Dis. 43:748–756.
2006. View
Article : Google Scholar : PubMed/NCBI
|
|
35
|
Bian JR, Nie W, Zang YS, Fang Z, Xiu QY
and Xu XX: Clinical aspects and cytokine response in adults with
seasonal influenza infection. Int J Clin Exp Med. 7:5593–5602.
2014.PubMed/NCBI
|
|
36
|
Yang ZF, Mok CK, Liu XQ, Li XB, He JF,
Guan WD, Xu YH, Pan WQ, Chen LY, Lin YP, et al: Clinical,
virological and immunological features from patients infected with
re-emergent avian-origin human H7N9 influenza disease of varying
severity in Guangdong province. PLoS One. 10:e01178462015.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Ramos I and Fernandez-Sesma A: Modulating
the innate immune response to influenza A virus: Potential
therapeutic use of anti-inflammatory drugs. Front Immunol.
6:3612015. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Droebner K, Reiling SJ and Planz O: Role
of hypercytokinemia in NF-kappaB p50-deficient mice after H5N1
influenza A virus infection. J Virol. 82:11461–11466. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Hui KP, Lee SM, Cheung CY, Ng IH, Poon LL,
Guan Y, Ip NY, Lau AS and Peiris JS: Induction of proinflammatory
cytokines in primary human macrophages by influenza A virus (H5N1)
is selectively regulated by IFN regulatory factor 3 and p38 MAPK. J
Immunol. 182:1088–1098. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Lee N, Wong CK, Chan PK, Lun SW, Lui G,
Wong B, Hui DS, Lam CW, Cockram CS, Choi KW, et al:
Hypercytokinemia and hyperactivation of phospho-p38
mitogen-activated protein kinase in severe human influenza A virus
infection. Clin Infect Dis. 45:723–731. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
N'Guessan PD, Hippenstiel S, Etouem MO,
Zahlten J, Beermann W, Lindner D, Opitz B, Witzenrath M, Rosseau S,
Suttorp N, et al: Streptococcus pneumoniae induced p38 MAPK- and
NF-kappaB-dependent COX-2 expression in human lung epithelium. Am J
Physiol Lung Cell Mol Physiol. 290:L1131–L1138. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Singer CA, Baker KJ, McCaffrey A, AuCoin
DP, Dechert MA and Gerthoffer WT: p38 MAPK and NF-kappaB mediate
COX-2 expression in human airway myocytes. Am J Physiol Lung Cell
Mol Physiol. 285:L1087–L1098. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Lee SM, Cheung CY, Nicholls JM, Hui KP,
Leung CY, Uiprasertkul M, Tipoe GL, Lau YL, Poon LL, Ip NY, et al:
Hyperinduction of cyclooxygenase-2-mediated proinflammatory
cascade: A mechanism for the pathogenesis of avian influenza H5N1
infection. J Infect Dis. 198:525–535. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Carey MA, Bradbury JA, Seubert JM,
Langenbach R, Zeldin DC and Germolec DR: Contrasting effects of
cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response
to influenza A viral infection. J Immunol. 175:6878–6884. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Carey MA, Bradbury JA, Rebolloso YD,
Graves JP, Zeldin DC and Germolec DR: Pharmacologic inhibition of
COX-1 and COX-2 in influenza A viral infection in mice. PLoS One.
5:e116102010. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Zheng BJ, Chan KW, Lin YP, Zhao GY, Chan
C, Zhang HJ, Chen HL, Wong SS, Lau SK, Woo PC, et al: Delayed
antiviral plus immunomodulator treatment still reduces mortality in
mice infected by high inoculum of influenza A/H5N1 virus. Proc Natl
Acad Sci USA. 105:8091–8096. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Coulombe F, Jaworska J, Verway M, Tzelepis
F, Massoud A, Gillard J, Wong G, Kobinger G, Xing Z, Couture C, et
al: Targeted prostaglandin E2 inhibition enhances antiviral
immunity through induction of type I interferon and apoptosis in
macrophages. Immunity. 40:554–568. 2014. View Article : Google Scholar : PubMed/NCBI
|
