|
1
|
Samuel VT and Shulman GI: Mechanisms for
insulin resistance: Common threads and missing links. Cell.
148:852–871. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Turner N, Kowalski GM, Leslie SJ, Risis S,
Yang C, Lee-Young RS, Babb JR, Meikle PJ, Lancaster GI, Henstridge
DC, et al: Distinct patterns of tissue-specific lipid accumulation
during the induction of insulin resistance in mice by high-fat
feeding. Diabetologia. 56:1638–1648. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Tao X, Yin L, Xu L and Peng J: Dioscin: A
diverse acting natural compound with therapeutic potential in
metabolic diseases, cancer, inflammation and infections. Pharmacol
Res. (In press).
|
|
4
|
Kim S, Jwa H, Yanagawa Y and Park T:
Extract from dioscorea batatas ameliorates insulin resistance in
mice fed a high-fat diet. J Med Food. 15:527–534. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Aumsuwan P, Khan SI, Khan IA, Ali Z, Avula
B, Walker LA, Shariat-Madar Z, Helferich WG, Katzenellenbogen BS
and Dasmahapatra AK: The anticancer potential of steroidal saponin,
dioscin, isolated from wild yam (Dioscorea villosa) root extract in
invasive human breast cancer cell line MDA-MB-231 in vitro. Arch
Biochem Biophys. 591:98–110. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Liu C, Wang Y, Wu C, Pei R, Song J, Chen S
and Chen X: Dioscin's antiviral effect in vitro. Virus Res.
172:9–14. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Guo CH, Li X and Kang Y: The protective
effect of dioscin-containing serum on hydrogen peroxide injured
cardiomyocytes of neonate rats. Chin J Hosp Pharm. 13:1027–1031.
2012.(In Chinese).
|
|
8
|
Tao X, Wan X, Xu Y, Xu L, Qi Y, Yin L, Han
X, Lin Y and Peng J: Dioscin attenuates hepatic
ischemia-reperfusion injury in rats through inhibition of
oxidative-nitrative stress, inflammation and apoptosis.
Transplantation. 98:604–611. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Liu M, Xu L, Yin LH, Qi Y, Xu Y, Han X,
Zhao Y, Sun H, Yao J, Lin Y, et al: Corrigendum: Potent effects of
dioscin against obesity in mice. Sci Rep. 5:121832015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kwon H and Pessin JE: Adipokines mediate
inflammation and insulin resistance. Front Endocrinol (Lausanne).
4:712013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Hu X, Wang S, Xu J, Wang DB, Chen Y and
Yang GZ: Triterpenoid saponins from Stauntonia chinensis ameliorate
insulin resistance via the AMP-activated protein kinase and
IR/IRS-1/PI3K/Akt pathways in insulin-resistant HepG2 cells. Int J
Mol Sci. 15:10446–10458. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gallagher EJ, Fierz Y, Vijayakumar A,
Haddad N, Yakar S and LeRoith D: Inhibiting PI3K reduces mammary
tumor growth and induces hyperglycemia in a mouse model of insulin
resistance and hyperinsulinemia. Oncogene. 31:3213–3222. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hsieh MJ, Tsai TL, Hsieh YS, Wang CJ and
Chiou HL: Dioscin-induced autophagy mitigates cell apoptosis
through modulation of PI3K/Akt and ERK and JNK signaling pathways
in human lung cancer cell lines. Arch Toxicol. 87:1927–1937. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Plomgaard P, Bouzakri K, Krogh-Madsen R,
Mittendorfer B, Zierath JR and Pedersen BK: Tumor necrosis
factor-alpha induces skeletal muscle insulin resistance in healthy
human subjects via inhibition of Akt substrate 160 phosphorylation.
Diabetes. 54:2939–2945. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Copps KD and White MF: Regulation of
insulin sensitivity by serine/threonine phosphorylation of insulin
receptor substrate proteins IRS1 and IRS2. Diabetologia.
55:2565–2582. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Guo S: Insulin signaling, resistance, and
the metabolic syndrome: Insights from mouse models into disease
mechanisms. J Endocrinol. 220:T1–T23. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hu X, Wang M, Bei W, Han Z and Guo J: The
Chinese herbal medicine FTZ attenuates insulin resistance via IRS1
and PI3K in vitro and in rats with metabolic syndrome. J Transl
Med. 12:472014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhang Y, Hai J, Cao M, Zhang Y, Pei S,
Wang J and Zhang Q: Silibinin ameliorates steatosis and insulin
resistance during non-alcoholic fatty liver disease development
partly through targeting IRS-1/PI3K/Akt pathway. Int J
Immunopharmacol. 17:714–720. 2013. View Article : Google Scholar
|
|
20
|
Gao Y, Yang MF, Su YP, Jiang HM, You XJ,
Yang YJ and Zhang HL: Ginsenoside Re reduces insulin resistance
through activation of PPAR-γ pathway and inhibition of TNF-α
production. J Ethnopharmacol. 147:509–516. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Naowaboot J, Wannasiri S and Pannangpetch
P: Vernonia cinerea water extract improves insulin resistance in
high-fat diet-induced obese mice. Nutr Res. 56:51–60. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Cai Y, Wang Y, Zhi F, Xing QC and Chen YZ:
The effect of sanggua drink extract on insulin resistance through
the PI3K/AKT signaling pathway. Evid Based Complement Alternat Med.
2018:94079452018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Leng J, Chen MH, Zhou ZH, Lu YW, Wen XD
and Yang J: Triterpenoids-enriched extract from the aerial parts of
salvia miltiorrhiza regulates macrophage polarization and
ameliorates insulin resistance in high-fat fed mice. Phytother Res.
31:100–107. 2017. View
Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ranganathan G, Unal R, Pokrovskaya I,
Yao-Borengasser A, Phanavanh B, Lecka-Czernik B, Rasouli N and Kern
PA: The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue:
Effects of obesity, insulin resistance, and TZD treatment. J Lipid
Res. 47:2444–2450. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Liu K, Zhao W, Gao X, Huang F, Kou J and
Liu B: Diosgenin ameliorates palmitate-induced endothelial
dysfunction and insulin resistance via blocking IKKβ and IRS-1
pathways. Atherosclerosis. 223:350–358. 2012. View Article : Google Scholar : PubMed/NCBI
|
