Journal Articles
Review
Mechanisms shaping the role of ERK1/2 in cellular senescence (Review)
Junrong Zou, Tingting Lei, Pei Guo, Jason Yu, Qichao Xu, Yunfei Luo, Rong Ke, Deqiang Huang
Pages: 759-770 Published online on: 29 November 2018
Review
Pivotal prognostic and diagnostic role of the long non‑coding RNA colon cancer‑associated transcript 1 expression in human cancer (Review)
Ni Wang, Yang Yu, Boming Xu, Mingjiong Zhang, Quanpeng Li, Lin Miao
Pages: 771-782 Published online on: 04 December 2018
Review
PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review)
Youbang Xie, Xuefeng Shi, Kuo Sheng, Guoxiong Han, Wenqian Li, Qiangqiang Zhao, Baili Jiang, Jianming Feng, Jianping Li, Yuhai Gu
Pages: 783-791 Published online on: 03 December 2018
Article
Ferulic acid ameliorates cerebral infarction by activating Akt/mTOR/4E‑BP1/Bcl‑2 anti‑apoptotic signaling in the penumbral cortex following permanent cerebral ischemia in rats
Chin‑Yi Cheng, Shung‑Te Kao, Yu‑Chen Lee
Pages: 792-804 Published online on: 11 December 2018
Article
miR‑223‑3p/TIAL1 interaction is involved in the mechanisms associated with the neuroprotective effects of dexmedetomidine on hippocampal neuronal cells in vitro
Qi Wang, Hongmei Yu, Hong Yu, Meina Ma, Yali Ma, Rui Li
Pages: 805-812 Published online on: 11 December 2018
Article
Effects of menstrual blood‑derived stem cells on endometrial injury repair
Jia Hu, Kuangyu Song, Jing Zhang, Yiqiong Zhang, Bu‑Zhen Tan
Pages: 813-820 Published online on: 12 December 2018
Article
Theaflavins prevent cartilage degeneration via AKT/FOXO3 signaling in vitro
Jun Li, Jianping Zheng
Pages: 821-830 Published online on: 12 December 2018
Article
MicroRNA‑29a enhances cisplatin sensitivity in non‑small cell lung cancer through the regulation of REV3L
Xialin Chen, Hong Zhu, Wanli Ye, Yayun Cui, Ming Chen
Pages: 831-840 Published online on: 04 December 2018
Article
α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy
Guangwei Liu, Jiangkai Liu, Linping Pian, Songlin Gui, Baoping Lu
Pages: 841-850 Published online on: 04 December 2018
Article
A comprehensive competitive endogenous RNA network pinpoints key molecules in diabetic retinopathy
Yingcheng Wu, Keren Jia, Huiqun Wu, Aimin Sang, Lei Wang, Lili Shi, Kui Jiang, Jiancheng Dong
Pages: 851-860 Published online on: 03 December 2018
Article
Long noncoding RNA RUSC1‑AS‑N promotes cell proliferation and metastasis through Wnt/β‑catenin signaling in human breast cancer
Peng Zhou, Peng Liu, Jin Zhang
Pages: 861-868 Published online on: 14 December 2018
Article
Overexpression of activating transcription factor 3 exerts suppressive effects in HepG2 cells
Xiaoyan Li, Shengbing Zang, Haili Cheng, Jiasi Li, Aimin Huang
Pages: 869-876 Published online on: 29 November 2018
Article
High expression of ACTL8 is poor prognosis and accelerates cell progression in head and neck squamous cell carcinoma
Bo Li, Jie Zhu, Lei Meng
Pages: 877-884 Published online on: 03 December 2018
Article
Inactivation of RUNX3 protein expression in tongue squamous cell carcinoma and its association with clinicopathological characteristics
Wei‑Na Zhou, Yi‑Fei Du, Yang Zheng, Wei Zhang, Yu‑Nong Wu, Xiao‑Meng Song, Jin Bai
Pages: 885-894 Published online on: 29 November 2018
Article
Intranasal instillation of miR‑410 targeting IL‑4/IL‑13 attenuates airway inflammation in OVA‑induced asthmatic mice
Rong Jin, Sujuan Hu, Xiaomei Liu, Renzheng Guan, Ling Lu, Rongjun Lin
Pages: 895-900 Published online on: 28 November 2018
Article
Cordycepin induces Bax‑dependent apoptosis in colorectal cancer cells
Shang‑Ze Li, Jian‑Wei Ren, Jing Fei, Xiao‑Dong Zhang, Run‑Lei Du
Pages: 901-908 Published online on: 03 December 2018
Article
High expression of RAB38 promotes malignant progression of pancreatic cancer
Bao‑Yu Li, Li‑Jie He, Xiang‑Lian Zhang, Hui Liu, Bin Liu
Pages: 909-918 Published online on: 10 December 2018
Article
In vitro analysis of the role of tumor necrosis factor‑stimulated gene‑6 in keloid
Xinyi Li, Zhao Chen, Xiaojing Li, Hui Wang
Pages: 919-926 Published online on: 14 December 2018
Article
Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen‑induced retinopathy in mice Erratum in /10.3892/mmr.2020.11753
Shuai Wang, Li‑Yang Ji, Li Li, Jing‑Min Li
Pages: 927-934 Published online on: 13 December 2018
Article
MicroRNA‑363‑3p inhibits hepatocarcinogenesis by targeting HMGA2 and is associated with liver cancer stage
Jing Wang, Huimin Liang, Haize Ge, Xinling Guo, Dongmei Gu, Yuhua Yuan
Pages: 935-942 Published online on: 29 November 2018
Article
Concentrated growth factor exudate enhances the proliferation of human periodontal ligament cells in the presence of TNF‑α
Xiaoju Li, Huixiao Yang, Zijian Zhang, Zhonghai Yan, Huling Lv, Yan Zhang, Bin Wu
Pages: 943-950 Published online on: 03 December 2018
Article
Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR‑223 expression
Wenhua Du, Lingkai Su, Ning Zhang, Huiming Wang
Pages: 951-958 Published online on: 13 December 2018
Article
Investigation into the underlying molecular mechanisms of white adipose tissue through comparative transcriptome analysis of multiple tissues
Song Zhang, Li Wang, Linsen Zan
Pages: 959-966 Published online on: 11 December 2018
Article
Reprogramming factors induce proliferation and inhibit apoptosis of melanoma cells by changing the expression of particular genes
Yang Wang, Hua‑Jun Sun, Rong‑Gui Li, Xiao‑Mei Wang, Zhi‑Qiang Cheng, Nan Lou
Pages: 967-973 Published online on: 12 December 2018
Article
Expression of miR‑542‑3p in osteosarcoma with miRNA microarray data, and its potential signaling pathways
Zhen Li, Jian‑Ni Yao, Wen‑Ting Huang, Rong‑Quan He, Jie Ma, Gang Chen, Qing‑Jun Wei
Pages: 974-983 Published online on: 13 December 2018
Article
Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species
Uddin Md Nazim, Honghua Yin, Sang‑Youel Park
Pages: 984-993 Published online on: 12 December 2018
Article
Construction and analysis of the lncRNA‑miRNA‑mRNA network based on competitive endogenous RNA reveals functional genes in heart failure
Guohong Wang, Xianghui Zheng, Yang Zheng, Rui Cao, Maomao Zhang, Yong Sun, Jian Wu
Pages: 994-1003 Published online on: 10 December 2018
Article
Identification of putative drugs for gastric adenocarcinoma utilizing differentially expressed genes and connectivity map
Zu‑Xuan Chen, Xiao‑Ping Zou, Huang‑Qun Yan, Rui Zhang, Jin‑Shu Pang, Xin‑Gan Qin, Rong‑Quan He, Jie Ma, Zhen‑Bo Feng, Gang Chen, Ting‑Qing Gan
Pages: 1004-1015 Published online on: 13 December 2018
Article
Novel adeno‑associated virus‑based genetic vaccines encoding hepatitis C virus E2 glycoprotein elicit humoral immune responses in mice
Fengqin Zhu, Yibo Wang, Zhen Xu, Haiyang Qu, Hairong Zhang, Lingling Niu, Honglu Xue, Dehuai Jing, Heng He
Pages: 1016-1023 Published online on: 11 December 2018
Article
Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway
Zhenlong Ran, Yueling Zhang, Xiaoying Wen, Jingxue Ma
Pages: 1024-1031 Published online on: 12 December 2018
Article
Magnesium sulfate ameliorates carbon monoxide‑induced cerebral injury in male rats
Gholamreza Bagheri, Ramin Rezaee, Konstantinos Tsarouhas, Anca Oana Docea, Jafar Shahraki, Malihe Shahriari, Martin F. Wilks, Hosseinali Jahantigh, Kaveh Tabrizian, Alireza Abdollahi Moghadam, Somayeh Bagheri, Demetrios A. Spandidos, Aristidis Tsatsakis, Mahmoud Hashemzaei
Pages: 1032-1039 Published online on: 17 December 2018
Article
A SIRT1 agonist reduces cognitive decline in type 2 diabetic rats through antioxidative and anti‑inflammatory mechanisms
Fei Wang, Yanchang Shang, Rong Zhang, Xiangyang Gao, Qiang Zeng
Pages: 1040-1048 Published online on: 27 November 2018
Article
MicroRNA‑3666 suppresses the growth and migration of glioblastoma cells by targeting KDM2A
Taotao Shou, Huyin Yang, Jia Lv, Dai Liu, Xiaoyang Sun
Pages: 1049-1055 Published online on: 27 November 2018
Article
An experimental study of amniotic lacrimal duct stents in the treatment of perimenopausal female rabbits with dry eye
Mingyang Ma, Qing Yuan, Lei Ye, Kangcheng Liu, Linhong Ye, You‑Lan Min, Nan Jiang, Qinghai Li, Wenqing Shi, Xiaowei Xu, Peiwen Zhu, Yi Shao
Pages: 1056-1064 Published online on: 10 December 2018
Article
Identification of gene biomarkers in patients with postmenopausal osteoporosis
Chenggang Yang, Jing Ren, Bangling Li, Chuandi Jin, Cui Ma, Cheng Cheng, Yaolan Sun, Xiaofeng Shi
Pages: 1065-1073 Published online on: 12 December 2018
Article
Irisin regulates the expression of BDNF and glycometabolism in diabetic rats
Lingning Huang, Sunjie Yan, Li Luo, Liyong Yang
Pages: 1074-1082 Published online on: 12 December 2018
Article
Hypertonic saline maintains coagulofibrinolytic homeostasis following moderate‑to‑severe traumatic brain injury by regulating monocyte phenotype via expression of lncRNAs
Xiping Yang, Yisheng Chen, Jianxin Li, Lijun Chen, Hefei Ren, Yang Liu, Xinyu Zhang
Pages: 1083-1091 Published online on: 12 December 2018
Article
MEK inhibitor enhanced the antitumor effect of oxaliplatin and 5‑fluorouracil in MEK1 Q56P‑mutant colorectal cancer cells
Changwen Jing, Huizi Li, Yuanyuan Du, Haixia Cao, Siwen Liu, Zhuo Wang, Rong Ma, Jifeng Feng, Jianzhong Wu
Pages: 1092-1100 Published online on: 07 December 2018
Article
Construction of a transcription factor‑long non‑coding RNA‑microRNA network for the identification of key regulators in lung adenocarcinoma and lung squamous cell carcinoma
Shuai Zhao, Hong Chen, Beichen Ding, Jianing Li, Fuzhen Lv, Kaiyu Han, Dan Zhou, Baiquan Yu, Yao Yu, Wei Zhang
Pages: 1101-1109 Published online on: 14 December 2018
Article
miR‑15a‑3p affects the proliferation, migration and apoptosis of lens epithelial cells
Shu‑Jun Liu, Wen‑Ting Wang, Feng‑Lan Zhang, Yong‑Hong Yu, Hua‑Jun Yu, Yan Liang, Ning Li, Yuan‑Bin Li
Pages: 1110-1116 Published online on: 11 December 2018
Article
Knockdown of ribosomal protein S15A inhibits human kidney cancer cell growth in vitro and in vivo
Jiayu Liang, Zhihong Liu, Zijun Zou, Xiangxiu Wang, Yongquan Tang, Chuan Zhou, Kan Wu, Fuxun Zhang, Yiping Lu
Pages: 1117-1127 Published online on: 12 December 2018
Article
A risk assessment model for the prognosis of osteosarcoma utilizing differentially expressed lncRNAs
Kai Sun, Jianmin Zhao
Pages: 1128-1138 Published online on: 14 December 2018
Article
Intranasal erythropoietin ameliorates neurological function impairments and neural pathology in mice with chronic alcoholism by regulating autophagy‑related Nrf2 degradation
Xuedan Nie, Wenbo Wang, Qin Wang, Dan Zhu, Hongshan Song
Pages: 1139-1149 Published online on: 29 November 2018
Article
Contribution of regulatory T cells to immune tolerance and association of microRNA‑210 and Foxp3 in preeclampsia
Jiying Chen, Lijian Zhao, Dengchuan Wang, Yanbin Xu, Haijie Gao, Wenqing Tan, Chenhong Wang
Pages: 1150-1158 Published online on: 10 December 2018
Article
Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells
Shuang Liu, Huan Hou, Panpan Zhang, Yifan Wu, Xuanhong He, Hua Li, Nianlong Yan
Pages: 1159-1167 Published online on: 04 December 2018
Article
Expression and potential molecular mechanisms of miR‑204‑5p in breast cancer, based on bioinformatics and a meta‑analysis of 2,306 cases
Kai‑Teng Cai, An‑Gui Liu, Ze‑Feng Wang, Hang‑Wei Jiang, Jing‑Jing Zeng, Rong‑Quan He, Jie Ma, Gang Chen, Jin‑Cai Zhong
Pages: 1168-1184 Published online on: 14 December 2018
Article
Melatonin ameliorates ANIT‑induced cholestasis by activating Nrf2 through a PI3K/Akt‑dependent pathway in rats
Yunzhou Li, Han Yu, Zongying Xu, Shaohua Shi, Dingnan Wang, Xinghua Shi, Yuchen Wang, Baihui Zeng, Huifang Deng, Xiulan Deng, Xianggen Zhong
Pages: 1185-1193 Published online on: 12 December 2018
Article
Expression of C1q in the serum of patients with non‑severe aplastic anemia, and its association with disease severity
Shaoxue Ding, Chunyan Liu, Yang Li, Hui Liu, Zhaoyun Liu, Tong Chen, Tian Zhang, Zonghong Shao, Rong Fu
Pages: 1194-1202 Published online on: 12 December 2018
Article
Metformin attenuates cells stemness and epithelial‑mesenchymal transition in colorectal cancer cells by inhibiting the Wnt3a/β‑catenin pathway
Chu Zhang, Yuchen Wang
Pages: 1203-1209 Published online on: 14 December 2018
Article
Long non‑coding RNA MLK7‑AS1 promotes proliferation in human colorectal cancer via downregulation of p21 expression
Rui Zhang, Jibin Li, Xiaofei Yan, Keer Jin, Wenya Li, Xin Liu, Jianfeng Zhao, Wen Shang, Xiang Zhao
Pages: 1210-1221 Published online on: 28 November 2018
Article
Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression
Chi Zhang, Weizhong Yu, Chongbo Huang, Qinghe Ding, Chizhang Liang, Le Wang, Zhiqi Hou, Zhiyong Zhang
Pages: 1222-1229 Published online on: 04 December 2018
Article
Dioscin attenuates high‑fat diet‑induced insulin resistance of adipose tissue through the IRS‑1/PI3K/Akt signaling pathway
Haijuan Li, Lianzhi Yu, Changsheng Zhao
Pages: 1230-1237 Published online on: 27 November 2018
Article
Characterization of estrogenic active ingredients in Cuscuta chinensis Lam. based on spectral characteristics and high‑performance liquid chromatography/quadrupole time‑of‑flight mass spectrometry
Jing‑Xin Ding, Wen‑Lan Li, Yang Hu, Hui Song, Xiang‑Ming Sun, Yu‑Bin Ji
Pages: 1238-1247 Published online on: 12 December 2018
Article
Long non‑coding RNA DLX6‑AS1 promotes proliferation by acting as a ceRNA targeting miR‑199a in cervical cancer
Xiaobo Wang, Yiqin Lin, Jiangang Liu
Pages: 1248-1255 Published online on: 07 December 2018
Article
Role of mitochondrial damage in Cr(VI)‑induced endoplasmic reticulum stress in L‑02 hepatocytes
Qi Liang, Yujing Zhang, Manfeng Huang, Yuanyuan Xiao, Fang Xiao
Pages: 1256-1265 Published online on: 29 November 2018
Article
Upregulated IGF‑1 in the lungs of asthmatic mice originates from alveolar macrophages
Jing He, Mimi Mu, Helong Wang, Hua Ma, Xu Tang, Qiang Fang, Shujun Guo, Chuanwang Song
Pages: 1266-1271 Published online on: 05 December 2018
Article
Apolipoprotein M induces inhibition of inflammatory responses via the S1PR1 and DHCR24 pathways
Min Wang, Guang‑Hua Luo, Hong Liu, You‑Pu Zhang, Bin Wang, Dong‑Mei Di, Xiang‑Hong Zhan, Yang Yu, Shuang Yao, Xiao‑Ying Zhang, Ning Xu
Pages: 1272-1283 Published online on: 12 December 2018
Article
Role of the mTOR‑FOXO1 pathway in obesity‑associated renal tubulointerstitial inflammation
Hong Sun, Xinyu Shao, Jiajia He, Michal Golos, Bimin Shi
Pages: 1284-1293 Published online on: 05 December 2018
Article
A novel four‑snoRNA signature for predicting the survival of patients with uveal melanoma
Qiong Yi, Wen‑Jin Zou
Pages: 1294-1301 Published online on: 14 December 2018
Article
Evaluation of a DNA vaccine encoding Brucella BvrR in BALB/c mice
Bo Chen, Baoshan Liu, Zhina Zhao, Guizhen Wang
Pages: 1302-1308 Published online on: 11 December 2018
Article
Salvianolic acid B, an antioxidant derived from Salvia militarize, protects mice against γ‑radiation‑induced damage through Nrf2/Bach1
Ruifang Zhou, Haishan Long, Bei Zhang, Zhizhao Lao, Quanyu Zheng, Tiancheng Wang, Yongxin Zhang, Qingguang Wu, Xiaoping Lai, Geng Li, Lizhu Lin
Pages: 1309-1317 Published online on: 03 December 2018
Article
Melatonin attenuates renal fibrosis in diabetic mice by activating the AMPK/PGC1α signaling pathway and rescuing mitochondrial function
Jian Li, Nan Li, Shuangtong Yan, Yanhui Lu, Xinyu Miao, Zhaoyan Gu, Yinghong Shao
Pages: 1318-1330 Published online on: 29 November 2018
Article
MicroRNA‑506‑3p reverses gefitinib resistance in non‑small cell lung cancer by targeting Yes‑associated protein 1
Junfei Zhu, Lianqin Tao, Litong Jin
Pages: 1331-1339 Published online on: 29 November 2018
Article
miR‑340‑5p: A potential direct regulator of Nrf2 expression in the post‑exercise skeletal muscle of mice
Tao Mei, Yujia Liu, Jianxiong Wang, Ying Zhang
Pages: 1340-1348 Published online on: 13 December 2018
Article
Early diagnosis of trisomy 21, trisomy 18 and trisomy 13 using nuchal translucency thickness and ductus venosus blood flow waveform in West China
Ying Tang, Hong Luo, Dezhi Mu, Taizhu Yang, Qi Zhu, Fan Yang, Guanjian Liu
Pages: 1349-1355 Published online on: 12 December 2018
Article
Bioinformatics analysis of the interactions among lncRNA, miRNA and mRNA expression, genetic mutations and epigenetic modifications in hepatocellular carcinoma
Chengjie Lin, Guandou Yuan, Zhigao Hu, Yonglian Zeng, Xiaoqiang Qiu, Hongping Yu, Songqing He
Pages: 1356-1364 Published online on: 05 December 2018
Article
A GLP‑1 receptor agonist attenuates human islet amyloid polypeptide‑induced autophagy and apoptosis in MIN6 cells
Xiong Chen, Tingting Huang, Yujuan Shi, Luyin Wang, Wei Li, Feixia Shen, Xuemei Gu
Pages: 1365-1371 Published online on: 11 December 2018
Article
Costunolide isolated from Vladimiria souliei inhibits the proliferation and induces the apoptosis of HepG2 cells
Jingxin Mao, Man Yi, Yunyi Tao, Yuanshe Huang, Min Chen
Pages: 1372-1379 Published online on: 11 December 2018
Article
MicroRNA‑766 inhibits the malignant biological behaviours of pancreatic ductal adenocarcinoma by directly targeting ETS1
Shiquan Li, Guoqiang Yan, Meng Yue, Zhenhua Kang, Lei Wang
Pages: 1380-1387 Published online on: 14 December 2018
Article
MicroRNA‑146a inhibits the inflammatory responses induced by interleukin‑17A during the infection of Helicobacter pylori
Na Li, Jianlong Wang, Wenqian Yu, Kai Dong, Feng You, Biao Si, Bin Tang, Yan Zhang, Tongjian Wang, Bin Qiao
Pages: 1388-1395 Published online on: 05 December 2018
Article
Gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF‑κB signaling pathways
Qiang Liu, Peng Shan, Haibin Li
Pages: 1396-1402 Published online on: 04 December 2018
Article
MicroRNA‑509 targets PAX6 to inhibit cell proliferation and invasion in papillary thyroid carcinoma Retraction in /10.3892/mmr.2022.12910
Shuilong Zhang, Qiang Wang, Dewei Li, Bo Huang, Xia Hou, Dongliang Wang
Pages: 1403-1409 Published online on: 12 December 2018
Article