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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2019 Volume 19 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mechanisms shaping the role of ERK1/2 in cellular senescence (Review)

Junrong Zou, Tingting Lei, Pei Guo, Jason Yu, Qichao Xu, Yunfei Luo, Rong Ke, Deqiang Huang
Pages: 759-770
Published online on: 29 November 2018

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Review Open Access

Pivotal prognostic and diagnostic role of the long non‑coding RNA colon cancer‑associated transcript 1 expression in human cancer (Review)

Ni Wang, Yang Yu, Boming Xu, Mingjiong Zhang, Quanpeng Li, Lin Miao
Pages: 771-782
Published online on: 04 December 2018

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Review Open Access

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review)

Youbang Xie, Xuefeng Shi, Kuo Sheng, Guoxiong Han, Wenqian Li, Qiangqiang Zhao, Baili Jiang, Jianming Feng, Jianping Li, Yuhai Gu
Pages: 783-791
Published online on: 03 December 2018

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Article

Ferulic acid ameliorates cerebral infarction by activating Akt/mTOR/4E‑BP1/Bcl‑2 anti‑apoptotic signaling in the penumbral cortex following permanent cerebral ischemia in rats

Chin‑Yi Cheng, Shung‑Te Kao, Yu‑Chen Lee
Pages: 792-804
Published online on: 11 December 2018

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Article Open Access

miR‑223‑3p/TIAL1 interaction is involved in the mechanisms associated with the neuroprotective effects of dexmedetomidine on hippocampal neuronal cells in vitro

Qi Wang, Hongmei Yu, Hong Yu, Meina Ma, Yali Ma, Rui Li
Pages: 805-812
Published online on: 11 December 2018

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Article Open Access

Effects of menstrual blood‑derived stem cells on endometrial injury repair

Jia Hu, Kuangyu Song, Jing Zhang, Yiqiong Zhang, Bu‑Zhen Tan
Pages: 813-820
Published online on: 12 December 2018

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Article Open Access

Theaflavins prevent cartilage degeneration via AKT/FOXO3 signaling in vitro

Jun Li, Jianping Zheng
Pages: 821-830
Published online on: 12 December 2018

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Article Open Access

MicroRNA‑29a enhances cisplatin sensitivity in non‑small cell lung cancer through the regulation of REV3L

Xialin Chen, Hong Zhu, Wanli Ye, Yayun Cui, Ming Chen
Pages: 831-840
Published online on: 04 December 2018

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Article Open Access

α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy

Guangwei Liu, Jiangkai Liu, Linping Pian, Songlin Gui, Baoping Lu
Pages: 841-850
Published online on: 04 December 2018

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Article Open Access

A comprehensive competitive endogenous RNA network pinpoints key molecules in diabetic retinopathy

Yingcheng Wu, Keren Jia, Huiqun Wu, Aimin Sang, Lei Wang, Lili Shi, Kui Jiang, Jiancheng Dong
Pages: 851-860
Published online on: 03 December 2018

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Article Open Access

Long noncoding RNA RUSC1‑AS‑N promotes cell proliferation and metastasis through Wnt/β‑catenin signaling in human breast cancer

Peng Zhou, Peng Liu, Jin Zhang
Pages: 861-868
Published online on: 14 December 2018

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Article Open Access

Overexpression of activating transcription factor 3 exerts suppressive effects in HepG2 cells

Xiaoyan Li, Shengbing Zang, Haili Cheng, Jiasi Li, Aimin Huang
Pages: 869-876
Published online on: 29 November 2018

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Article Open Access

High expression of ACTL8 is poor prognosis and accelerates cell progression in head and neck squamous cell carcinoma

Bo Li, Jie Zhu, Lei Meng
Pages: 877-884
Published online on: 03 December 2018

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Article Open Access

Inactivation of RUNX3 protein expression in tongue squamous cell carcinoma and its association with clinicopathological characteristics

Wei‑Na Zhou, Yi‑Fei Du, Yang Zheng, Wei Zhang, Yu‑Nong Wu, Xiao‑Meng Song, Jin Bai
Pages: 885-894
Published online on: 29 November 2018

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Article Open Access

Intranasal instillation of miR‑410 targeting IL‑4/IL‑13 attenuates airway inflammation in OVA‑induced asthmatic mice

Rong Jin, Sujuan Hu, Xiaomei Liu, Renzheng Guan, Ling Lu, Rongjun Lin
Pages: 895-900
Published online on: 28 November 2018

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Article Open Access

Cordycepin induces Bax‑dependent apoptosis in colorectal cancer cells

Shang‑Ze Li, Jian‑Wei Ren, Jing Fei, Xiao‑Dong Zhang, Run‑Lei Du
Pages: 901-908
Published online on: 03 December 2018

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Article Open Access

High expression of RAB38 promotes malignant progression of pancreatic cancer

Bao‑Yu Li, Li‑Jie He, Xiang‑Lian Zhang, Hui Liu, Bin Liu
Pages: 909-918
Published online on: 10 December 2018

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Article Open Access

In vitro analysis of the role of tumor necrosis factor‑stimulated gene‑6 in keloid

Xinyi Li, Zhao Chen, Xiaojing Li, Hui Wang
Pages: 919-926
Published online on: 14 December 2018

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Article Open Access

Oxidative stress, autophagy and pyroptosis in the neovascularization of oxygen‑induced retinopathy in mice Erratum in /10.3892/mmr.2020.11753

Shuai Wang, Li‑Yang Ji, Li Li, Jing‑Min Li
Pages: 927-934
Published online on: 13 December 2018

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Article Open Access

MicroRNA‑363‑3p inhibits hepatocarcinogenesis by targeting HMGA2 and is associated with liver cancer stage

Jing Wang, Huimin Liang, Haize Ge, Xinling Guo, Dongmei Gu, Yuhua Yuan
Pages: 935-942
Published online on: 29 November 2018

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Article Open Access

Concentrated growth factor exudate enhances the proliferation of human periodontal ligament cells in the presence of TNF‑α

Xiaoju Li, Huixiao Yang, Zijian Zhang, Zhonghai Yan, Huling Lv, Yan Zhang, Bin Wu
Pages: 943-950
Published online on: 03 December 2018

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Article Open Access

Exosomes derived from preadipocytes improve osteogenic differentiation, potentially via reduced miR‑223 expression

Wenhua Du, Lingkai Su, Ning Zhang, Huiming Wang
Pages: 951-958
Published online on: 13 December 2018

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Article Open Access

Investigation into the underlying molecular mechanisms of white adipose tissue through comparative transcriptome analysis of multiple tissues

Song Zhang, Li Wang, Linsen Zan
Pages: 959-966
Published online on: 11 December 2018

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Article Open Access

Reprogramming factors induce proliferation and inhibit apoptosis of melanoma cells by changing the expression of particular genes

Yang Wang, Hua‑Jun Sun, Rong‑Gui Li, Xiao‑Mei Wang, Zhi‑Qiang Cheng, Nan Lou
Pages: 967-973
Published online on: 12 December 2018

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Article Open Access

Expression of miR‑542‑3p in osteosarcoma with miRNA microarray data, and its potential signaling pathways

Zhen Li, Jian‑Ni Yao, Wen‑Ting Huang, Rong‑Quan He, Jie Ma, Gang Chen, Qing‑Jun Wei
Pages: 974-983
Published online on: 13 December 2018

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Article Open Access

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species Retraction in /10.3892/mmr.2026.13804

Uddin Md Nazim, Honghua Yin, Sang‑Youel Park
Pages: 984-993
Published online on: 12 December 2018

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Article Open Access

Construction and analysis of the lncRNA‑miRNA‑mRNA network based on competitive endogenous RNA reveals functional genes in heart failure

Guohong Wang, Xianghui Zheng, Yang Zheng, Rui Cao, Maomao Zhang, Yong Sun, Jian Wu
Pages: 994-1003
Published online on: 10 December 2018

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Article Open Access

Identification of putative drugs for gastric adenocarcinoma utilizing differentially expressed genes and connectivity map

Zu‑Xuan Chen, Xiao‑Ping Zou, Huang‑Qun Yan, Rui Zhang, Jin‑Shu Pang, Xin‑Gan Qin, Rong‑Quan He, Jie Ma, Zhen‑Bo Feng, Gang Chen, Ting‑Qing Gan
Pages: 1004-1015
Published online on: 13 December 2018

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Article Open Access

Novel adeno‑associated virus‑based genetic vaccines encoding hepatitis C virus E2 glycoprotein elicit humoral immune responses in mice

Fengqin Zhu, Yibo Wang, Zhen Xu, Haiyang Qu, Hairong Zhang, Lingling Niu, Honglu Xue, Dehuai Jing, Heng He
Pages: 1016-1023
Published online on: 11 December 2018

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Article Open Access

Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway

Zhenlong Ran, Yueling Zhang, Xiaoying Wen, Jingxue Ma
Pages: 1024-1031
Published online on: 12 December 2018

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Article Open Access

Magnesium sulfate ameliorates carbon monoxide‑induced cerebral injury in male rats

Gholamreza Bagheri, Ramin Rezaee, Konstantinos Tsarouhas, Anca Oana Docea, Jafar Shahraki, Malihe Shahriari, Martin F. Wilks, Hosseinali Jahantigh, Kaveh Tabrizian, Alireza Abdollahi Moghadam, Somayeh Bagheri, Demetrios A. Spandidos, Aristidis Tsatsakis, Mahmoud Hashemzaei
Pages: 1032-1039
Published online on: 17 December 2018

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Article Open Access

A SIRT1 agonist reduces cognitive decline in type 2 diabetic rats through antioxidative and anti‑inflammatory mechanisms

Fei Wang, Yanchang Shang, Rong Zhang, Xiangyang Gao, Qiang Zeng
Pages: 1040-1048
Published online on: 27 November 2018

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Article Open Access

MicroRNA‑3666 suppresses the growth and migration of glioblastoma cells by targeting KDM2A

Taotao Shou, Huyin Yang, Jia Lv, Dai Liu, Xiaoyang Sun
Pages: 1049-1055
Published online on: 27 November 2018

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Article Open Access

An experimental study of amniotic lacrimal duct stents in the treatment of perimenopausal female rabbits with dry eye

Mingyang Ma, Qing Yuan, Lei Ye, Kangcheng Liu, Linhong Ye, You‑Lan Min, Nan Jiang, Qinghai Li, Wenqing Shi, Xiaowei Xu, Peiwen Zhu, Yi Shao
Pages: 1056-1064
Published online on: 10 December 2018

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Article Open Access

Identification of gene biomarkers in patients with postmenopausal osteoporosis

Chenggang Yang, Jing Ren, Bangling Li, Chuandi Jin, Cui Ma, Cheng Cheng, Yaolan Sun, Xiaofeng Shi
Pages: 1065-1073
Published online on: 12 December 2018

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Article Open Access

Irisin regulates the expression of BDNF and glycometabolism in diabetic rats

Lingning Huang, Sunjie Yan, Li Luo, Liyong Yang
Pages: 1074-1082
Published online on: 12 December 2018

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Article Open Access

Hypertonic saline maintains coagulofibrinolytic homeostasis following moderate‑to‑severe traumatic brain injury by regulating monocyte phenotype via expression of lncRNAs

Xiping Yang, Yisheng Chen, Jianxin Li, Lijun Chen, Hefei Ren, Yang Liu, Xinyu Zhang
Pages: 1083-1091
Published online on: 12 December 2018

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Article Open Access

MEK inhibitor enhanced the antitumor effect of oxaliplatin and 5‑fluorouracil in MEK1 Q56P‑mutant colorectal cancer cells

Changwen Jing, Huizi Li, Yuanyuan Du, Haixia Cao, Siwen Liu, Zhuo Wang, Rong Ma, Jifeng Feng, Jianzhong Wu
Pages: 1092-1100
Published online on: 07 December 2018

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Article Open Access

Construction of a transcription factor‑long non‑coding RNA‑microRNA network for the identification of key regulators in lung adenocarcinoma and lung squamous cell carcinoma

Shuai Zhao, Hong Chen, Beichen Ding, Jianing Li, Fuzhen Lv, Kaiyu Han, Dan Zhou, Baiquan Yu, Yao Yu, Wei Zhang
Pages: 1101-1109
Published online on: 14 December 2018

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Article Open Access

miR‑15a‑3p affects the proliferation, migration and apoptosis of lens epithelial cells

Shu‑Jun Liu, Wen‑Ting Wang, Feng‑Lan Zhang, Yong‑Hong Yu, Hua‑Jun Yu, Yan Liang, Ning Li, Yuan‑Bin Li
Pages: 1110-1116
Published online on: 11 December 2018

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Article Open Access

Knockdown of ribosomal protein S15A inhibits human kidney cancer cell growth in vitro and in vivo

Jiayu Liang, Zhihong Liu, Zijun Zou, Xiangxiu Wang, Yongquan Tang, Chuan Zhou, Kan Wu, Fuxun Zhang, Yiping Lu
Pages: 1117-1127
Published online on: 12 December 2018

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Article Open Access

A risk assessment model for the prognosis of osteosarcoma utilizing differentially expressed lncRNAs

Kai Sun, Jianmin Zhao
Pages: 1128-1138
Published online on: 14 December 2018

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Article Open Access

Intranasal erythropoietin ameliorates neurological function impairments and neural pathology in mice with chronic alcoholism by regulating autophagy‑related Nrf2 degradation

Xuedan Nie, Wenbo Wang, Qin Wang, Dan Zhu, Hongshan Song
Pages: 1139-1149
Published online on: 29 November 2018

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Article Open Access

Contribution of regulatory T cells to immune tolerance and association of microRNA‑210 and Foxp3 in preeclampsia

Jiying Chen, Lijian Zhao, Dengchuan Wang, Yanbin Xu, Haijie Gao, Wenqing Tan, Chenhong Wang
Pages: 1150-1158
Published online on: 10 December 2018

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Article Open Access

Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells

Shuang Liu, Huan Hou, Panpan Zhang, Yifan Wu, Xuanhong He, Hua Li, Nianlong Yan
Pages: 1159-1167
Published online on: 04 December 2018

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Article Open Access

Expression and potential molecular mechanisms of miR‑204‑5p in breast cancer, based on bioinformatics and a meta‑analysis of 2,306 cases

Kai‑Teng Cai, An‑Gui Liu, Ze‑Feng Wang, Hang‑Wei Jiang, Jing‑Jing Zeng, Rong‑Quan He, Jie Ma, Gang Chen, Jin‑Cai Zhong
Pages: 1168-1184
Published online on: 14 December 2018

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Article Open Access

Melatonin ameliorates ANIT‑induced cholestasis by activating Nrf2 through a PI3K/Akt‑dependent pathway in rats

Yunzhou Li, Han Yu, Zongying Xu, Shaohua Shi, Dingnan Wang, Xinghua Shi, Yuchen Wang, Baihui Zeng, Huifang Deng, Xiulan Deng, Xianggen Zhong
Pages: 1185-1193
Published online on: 12 December 2018

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Article Open Access

Expression of C1q in the serum of patients with non‑severe aplastic anemia, and its association with disease severity

Shaoxue Ding, Chunyan Liu, Yang Li, Hui Liu, Zhaoyun Liu, Tong Chen, Tian Zhang, Zonghong Shao, Rong Fu
Pages: 1194-1202
Published online on: 12 December 2018

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Article Open Access

Metformin attenuates cells stemness and epithelial‑mesenchymal transition in colorectal cancer cells by inhibiting the Wnt3a/β‑catenin pathway

Chu Zhang, Yuchen Wang
Pages: 1203-1209
Published online on: 14 December 2018

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Article

Long non‑coding RNA MLK7‑AS1 promotes proliferation in human colorectal cancer via downregulation of p21 expression

Rui Zhang, Jibin Li, Xiaofei Yan, Keer Jin, Wenya Li, Xin Liu, Jianfeng Zhao, Wen Shang, Xiang Zhao
Pages: 1210-1221
Published online on: 28 November 2018

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Article

Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression

Chi Zhang, Weizhong Yu, Chongbo Huang, Qinghe Ding, Chizhang Liang, Le Wang, Zhiqi Hou, Zhiyong Zhang
Pages: 1222-1229
Published online on: 04 December 2018

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Article

Dioscin attenuates high‑fat diet‑induced insulin resistance of adipose tissue through the IRS‑1/PI3K/Akt signaling pathway

Haijuan Li, Lianzhi Yu, Changsheng Zhao
Pages: 1230-1237
Published online on: 27 November 2018

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Article

Characterization of estrogenic active ingredients in Cuscuta chinensis Lam. based on spectral characteristics and high‑performance liquid chromatography/quadrupole time‑of‑flight mass spectrometry

Jing‑Xin Ding, Wen‑Lan Li, Yang Hu, Hui Song, Xiang‑Ming Sun, Yu‑Bin Ji
Pages: 1238-1247
Published online on: 12 December 2018

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Article

Long non‑coding RNA DLX6‑AS1 promotes proliferation by acting as a ceRNA targeting miR‑199a in cervical cancer

Xiaobo Wang, Yiqin Lin, Jiangang Liu
Pages: 1248-1255
Published online on: 07 December 2018

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Article

Role of mitochondrial damage in Cr(VI)‑induced endoplasmic reticulum stress in L‑02 hepatocytes

Qi Liang, Yujing Zhang, Manfeng Huang, Yuanyuan Xiao, Fang Xiao
Pages: 1256-1265
Published online on: 29 November 2018

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Article

Upregulated IGF‑1 in the lungs of asthmatic mice originates from alveolar macrophages

Jing He, Mimi Mu, Helong Wang, Hua Ma, Xu Tang, Qiang Fang, Shujun Guo, Chuanwang Song
Pages: 1266-1271
Published online on: 05 December 2018

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Article

Apolipoprotein M induces inhibition of inflammatory responses via the S1PR1 and DHCR24 pathways

Min Wang, Guang‑Hua Luo, Hong Liu, You‑Pu Zhang, Bin Wang, Dong‑Mei Di, Xiang‑Hong Zhan, Yang Yu, Shuang Yao, Xiao‑Ying Zhang, Ning Xu
Pages: 1272-1283
Published online on: 12 December 2018

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Article

Role of the mTOR‑FOXO1 pathway in obesity‑associated renal tubulointerstitial inflammation

Hong Sun, Xinyu Shao, Jiajia He, Michal Golos, Bimin Shi
Pages: 1284-1293
Published online on: 05 December 2018

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Article

A novel four‑snoRNA signature for predicting the survival of patients with uveal melanoma

Qiong Yi, Wen‑Jin Zou
Pages: 1294-1301
Published online on: 14 December 2018

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Article

Evaluation of a DNA vaccine encoding Brucella BvrR in BALB/c mice

Bo Chen, Baoshan Liu, Zhina Zhao, Guizhen Wang
Pages: 1302-1308
Published online on: 11 December 2018

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Article Open Access

Salvianolic acid B, an antioxidant derived from Salvia militarize, protects mice against γ‑radiation‑induced damage through Nrf2/Bach1

Ruifang Zhou, Haishan Long, Bei Zhang, Zhizhao Lao, Quanyu Zheng, Tiancheng Wang, Yongxin Zhang, Qingguang Wu, Xiaoping Lai, Geng Li, Lizhu Lin
Pages: 1309-1317
Published online on: 03 December 2018

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Article

Melatonin attenuates renal fibrosis in diabetic mice by activating the AMPK/PGC1α signaling pathway and rescuing mitochondrial function

Jian Li, Nan Li, Shuangtong Yan, Yanhui Lu, Xinyu Miao, Zhaoyan Gu, Yinghong Shao
Pages: 1318-1330
Published online on: 29 November 2018

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MicroRNA‑506‑3p reverses gefitinib resistance in non‑small cell lung cancer by targeting Yes‑associated protein 1

Junfei Zhu, Lianqin Tao, Litong Jin
Pages: 1331-1339
Published online on: 29 November 2018

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miR‑340‑5p: A potential direct regulator of Nrf2 expression in the post‑exercise skeletal muscle of mice

Tao Mei, Yujia Liu, Jianxiong Wang, Ying Zhang
Pages: 1340-1348
Published online on: 13 December 2018

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Article

Early diagnosis of trisomy 21, trisomy 18 and trisomy 13 using nuchal translucency thickness and ductus venosus blood flow waveform in West China

Ying Tang, Hong Luo, Dezhi Mu, Taizhu Yang, Qi Zhu, Fan Yang, Guanjian Liu
Pages: 1349-1355
Published online on: 12 December 2018

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Article

Bioinformatics analysis of the interactions among lncRNA, miRNA and mRNA expression, genetic mutations and epigenetic modifications in hepatocellular carcinoma

Chengjie Lin, Guandou Yuan, Zhigao Hu, Yonglian Zeng, Xiaoqiang Qiu, Hongping Yu, Songqing He
Pages: 1356-1364
Published online on: 05 December 2018

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A GLP‑1 receptor agonist attenuates human islet amyloid polypeptide‑induced autophagy and apoptosis in MIN6 cells

Xiong Chen, Tingting Huang, Yujuan Shi, Luyin Wang, Wei Li, Feixia Shen, Xuemei Gu
Pages: 1365-1371
Published online on: 11 December 2018

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Article

Costunolide isolated from Vladimiria souliei inhibits the proliferation and induces the apoptosis of HepG2 cells

Jingxin Mao, Man Yi, Yunyi Tao, Yuanshe Huang, Min Chen
Pages: 1372-1379
Published online on: 11 December 2018

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MicroRNA‑766 inhibits the malignant biological behaviours of pancreatic ductal adenocarcinoma by directly targeting ETS1

Shiquan Li, Guoqiang Yan, Meng Yue, Zhenhua Kang, Lei Wang
Pages: 1380-1387
Published online on: 14 December 2018

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MicroRNA‑146a inhibits the inflammatory responses induced by interleukin‑17A during the infection of Helicobacter pylori

Na Li, Jianlong Wang, Wenqian Yu, Kai Dong, Feng You, Biao Si, Bin Tang, Yan Zhang, Tongjian Wang, Bin Qiao
Pages: 1388-1395
Published online on: 05 December 2018

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Article

Gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF‑κB signaling pathways

Qiang Liu, Peng Shan, Haibin Li
Pages: 1396-1402
Published online on: 04 December 2018

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Article

MicroRNA‑509 targets PAX6 to inhibit cell proliferation and invasion in papillary thyroid carcinoma Retraction in /10.3892/mmr.2022.12910

Shuilong Zhang, Qiang Wang, Dewei Li, Bo Huang, Xia Hou, Dongliang Wang
Pages: 1403-1409
Published online on: 12 December 2018

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Article Open Access

Different types of viral‑host junction found in HBV integration breakpoints in HBV‑infected patients

Peng Ruan, Xiufang Dai, Jun Sun, Chunping He, Chao Huang, Rui Zhou, Zhuo Cao, Lan Ye
Pages: 1410-1416
Published online on: 29 November 2018

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Editorial Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Review Open Access

Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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Article Open Access

FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Review Open Access

Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Review Open Access

Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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Article Open Access

ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Review Open Access

Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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Review Open Access

m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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Article Open Access

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Article Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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