|
1
|
Osuka S and Van Meir EG: Overcoming
therapeutic resistance in glioblastoma: The way forward. J Clin
Invest. 127:415–426. 2017. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hingtgen S, Figueiredo JL, Farrar C,
Duebgen M, Martinez-Quintanilla J, Bhere D and Shah K: Real-time
multi-modality imaging of glioblastoma tumor resection and
recurrence. J Neurooncol. 111:153–161. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Stupp R, Mason WP, van den Bent MJ, Weller
M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn
U, et al: Radiotherapy plus concomitant and adjuvant temozolomide
for glioblastoma. N Engl J Med. 352:987–996. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sharif S, Ghahremani MH and Soleimani M:
Delivery of exogenous miR-124 to glioblastoma multiform cells by
Wharton's Jelly mesenchymal stem cells decreases cell proliferation
and migration, and confers chemosensitivity. Stem Cell Rev.
14:236–246. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Mangraviti A, Tzeng SY, Gullotti D,
Kozielski KL, Kim JE, Seng M, Abbadi S, Schiapparelli P,
Sarabia-Estrada R, Vescovi A, et al: Non-virally engineered human
adipose mesenchymal stem cells produce BMP4, target brain tumors,
and extend survival. Biomaterials. 100:53–66. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Okada N, Lin CP, Ribeiro MC, Biton A, Lai
G, He X, Bu P, Vogel H, Jablons DM, Keller AC, et al: A positive
feedback between p53 and miR-34 miRNAs mediates tumor suppression.
Genes Dev. 28:438–450. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Adams BD, Wali VB, Cheng CJ, Inukai S,
Booth CJ, Agarwal S, Rimm DL, Győrffy B, Santarpia L, Pusztai L, et
al: miR-34a silences c-SRC to attenuate tumor growth in
triple-negative breast cancer. Cancer Res. 76:927–939. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lang FM, Hossain A, Gumin J, Momin EN,
Shimizu Y, Ledbetter D, Shahar T, Yamashita S, Parker Kerrigan B,
Fueyo J, et al: Mesenchymal stem cells as natural biofactories for
exosomes carrying miR-124a in the treatment of gliomas. Neuro
Oncol. 20:380–390. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Squatrito M, Brennan CW, Helmy K, Huse JT,
Petrini JH and Holland EC: Loss of ATM/Chk2/p53 pathway components
accelerates tumor development and contributes to radiation
resistance in gliomas. Cancer Cell. 18:619–629. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q,
Hjelmeland AB, Dewhirst MW, Bigner DD and Rich JN: Glioma stem
cells promote radioresistance by preferential activation of the DNA
damage response. Nature. 444:756–760. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Li L, Yuan L, Luo J, Gao J, Guo J and Xie
X: MiR-34a inhibits proliferation and migration of breast cancer
through down-regulation of Bcl-2 and SIRT1. Clin Exp Med.
13:109–117. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Filippi-Chiela EC, Bueno e Silva MM, Thomé
MP and Lenz G: Single-cell analysis challenges the connection
between autophagy and senescence induced by DNA damage. Autophagy.
11:1099–1113. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Crepin T, Carron C, Roubiou C, Gaugler B,
Gaiffe E, Simula-Faivre D, Ferrand C, Tiberghien P, Chalopin JM,
Moulin B, et al: ATG-induced accelerated immune senescence:
Clinical implications in renal transplant recipients. Am J
Transplant. 15:1028–1038. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Cawthon RM: Telomere measurement by
quantitative PCR. Nucleic Acids Res. 30:e472002. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Rupaimoole R and Slack FJ: MicroRNA
therapeutics: Towards a new era for the management of cancer and
other diseases. Nat Rev Drug Discov. 16:203–222. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Di Micco R: Sensing the breaks: Cytosolic
chromatin in senescence and cancer. Trends Mol Med. 23:1067–1070.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Louis DN, Perry A, Reifenberger G, von
Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD,
Kleihues P and Ellison DW: The 2016 world health organization
classification of tumors of the central nervous system: A summary.
Acta Neuropathol. 131:803–820. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Dolecek TA, Propp JM, Stroup NE and
Kruchko C: CBTRUS statistical report: Primary brain and central
nervous system tumors diagnosed in the United States in 2005–2009.
Neuro Oncol. 14 Suppl 5:v1–v49. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Furnari FB, Fenton T, Bachoo RM, Mukasa A,
Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, et al:
Malignant astrocytic glioma: Genetics, biology, and paths to
treatment. Genes Dev. 21:2683–2710. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Huang T, Kim CK, Alvarez AA, Pangeni RP,
Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, et al: MST4
phosphorylation of ATG4B regulates autophagic activity,
tumorigenicity, and radioresistance in glioblastoma. Cancer Cell.
32:840–855.e8. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Park JS, Kim IK, Han S, Park I, Kim C, Bae
J, Oh SJ, Lee S, Kim JH, Woo DC, et al: Normalization of tumor
vessels by Tie2 activation and Ang2 inhibition enhances drug
delivery and produces a favorable tumor microenvironment. Cancer
Cell. 30:953–967. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Menon LG, Shi VJ and Carroll RS:
Mesenchymal stromal cells as a drug delivery system. StemBook
[Internet]. Harvard Stem Cell Institute; Cambridge, MA:
2008-2009
|
|
25
|
Reagan MR and Kaplan DL: Concise review:
Mesenchymal stem cell tumor-homing: Detection methods in disease
model systems. Stem Cells. 29:920–927. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liu C, Kelnar K, Liu B, Chen X,
Calhoun-Davis T, Li H, Patrawala L, Yan H, Jeter C, Honorio S, et
al: The microRNA miR-34a inhibits prostate cancer stem cells and
metastasis by directly repressing CD44. Nat Med. 17:211–215. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kim NH, Kim HS, Li XY, Lee I, Choi HS,
Kang SE, Cha SY, Ryu JK, Yoon D, Fearon ER, et al: A p53/miRNA-34
axis regulates Snail1-dependent cancer cell epithelial-mesenchymal
transition. J Cell Biol. 195:417–433. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Chang TC, Wentzel EA, Kent OA,
Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M,
Ferlito M, Lowenstein CJ, et al: Transactivation of miR-34a by p53
broadly influences gene expression and promotes apoptosis. Mol
Cell. 26:745–752. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Dong X, Jin Z, Chen Y, Xu H, Ma C, Hong X,
Li Y and Zhao G: Knockdown of long non-coding RNA ANRIL inhibits
proliferation, migration, and invasion but promotes apoptosis of
human glioma cells by upregulation of miR-34a. J Cell Biochem.
119:2708–2718. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zhang F, Cui J, Liu X, Lv B, Liu X, Xie Z
and Yu B: Roles of microRNA-34a targeting SIRT1 in mesenchymal stem
cells. Stem Cell Res Ther. 6:1952015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Herskovits AZ and Guarente L: SIRT1 in
neurodevelopment and brain senescence. Neuron. 81:471–483. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li T, Ma J, Han X, Jia Y, Yuan H, Shui S
and Guo D: MicroRNA-320 enhances radiosensitivity of glioma through
down-regulation of sirtuin type 1 by directly targeting forkhead
box protein M1. Transl Oncol. 11:205–212. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Ciccia A and Elledge SJ: The DNA damage
response: Making it safe to play with knives. Mol Cell. 40:179–204.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Sulli G, Rommel A, Wang X, Kolar MJ, Puca
F, Saghatelian A, Plikus MV, Verma IM and Panda S: Pharmacological
activation of REV-ERBs is lethal in cancer and oncogene-induced
senescence. Nature. 553:351–355. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Boon RA, Iekushi K, Lechner S, Seeger T,
Fischer A, Heydt S, Kaluza D, Tréguer K, Carmona G, Bonauer A, et
al: MicroRNA-34a regulates cardiac ageing and function. Nature.
495:107–110. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Xu X, Chen W, Miao R, Zhou Y, Wang Z,
Zhang L, Wan Y, Dong Y, Qu K and Liu C: miR-34a induces cellular
senescence via modulation of telomerase activity in human
hepatocellular carcinoma by targeting FoxM1/c-Myc pathway.
Oncotarget. 6:3988–4004. 2015.PubMed/NCBI
|
