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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2019 Volume 19 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Pain polymorphisms and opioids: An evidence based review

Cláudia Margarida Pereira Vieira, Rosa Maria Fragoso, Deolinda Pereira, Rui Medeiros
Pages: 1423-1434
Published online on: 24 December 2018

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Article Open Access

Association of Epstein‑Barr virus infection with allogeneic hematopoietic stem cell transplantation in patients in Portugal

Joana Marinho‑Dias, Inês Baldaque, Carlos Pinho‑Vaz, Luís Leite, Rosa Branca, Fernando Campilho, António Campos, Rui Medeiros, Hugo Sousa
Pages: 1435-1442
Published online on: 24 December 2018

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Article Open Access

Low‑dose lipopolysaccharide inhibits neuronal apoptosis induced by cerebral ischemia/reperfusion injury via the PI3K/Akt/FoxO1 signaling pathway in rats

Fan He, Nannan Zhang, Yan Lv, Wenhao Sun, Huisheng Chen
Pages: 1443-1452
Published online on: 07 January 2019

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Article Open Access

Ticagrelor suppresses oxidized low‑density lipoprotein‑induced endothelial cell apoptosis and alleviates atherosclerosis in ApoE‑/‑ mice via downregulation of PCSK9

Xiaodong Xia, Jiao Li, Xue Liang, Shengjie Zhang, Tong Liu, Jinying Liu, Muhammad Arif, Guangping Li
Pages: 1453-1462
Published online on: 20 December 2018

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Article Open Access

MiR‑495 suppresses cell proliferation by directly targeting HMGA2 in lung cancer

Jiangtao Sun, Yanping Qiao, Tao Song, Haiwen Wang
Pages: 1463-1470
Published online on: 17 December 2018

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Article Open Access

Optimized protocols for γδ T cell expansion and lentiviral transduction

Rui‑Ning Wang, Qian Wen, Wen‑Ting He, Jia‑Hui Yang, Chao‑Ying Zhou, Wen‑Jing Xiong, Li Ma
Pages: 1471-1480
Published online on: 08 January 2019

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Article Open Access

miR‑675 promotes colorectal cancer cell growth dependent on tumor suppressor DMTF1

Xueliang Yang, Yang Lou, Minghua Wang, Chunlei Liu, Yanbo Liu, Weili Huang
Pages: 1481-1490
Published online on: 20 December 2018

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Article Open Access

MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway Retraction in /10.3892/mmr.2025.13762

Jin Zhang, Xianen Fa, Qingyong Zhang
Pages: 1491-1500
Published online on: 18 December 2018

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Article Open Access

Epithelial‑mesenchymal transition induced by bone morphogenetic protein 9 hinders cisplatin efficacy in ovarian cancer cells

Ying Wang, Bin Yang, Jinping Zhao, Xiaohui Yu, Xing Liu, Long Zhang, Yunjing Zhang, Xiaoli Li, Zhenhua Zhai
Pages: 1501-1508
Published online on: 03 January 2019

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Article Open Access

Epigallocatechin‑3‑gallate modulates long non‑coding RNA and mRNA expression profiles in lung cancer cells

Dong‑Li Hu, Guo Wang, Jing Yu, Li‑Hua Zhang, Yuan‑Fei Huang, Dan Wang, Hong‑Hao Zhou
Pages: 1509-1520
Published online on: 03 January 2019

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Article Open Access

Astrocytes enhance the tolerance of rat cortical neurons to glutamate excitotoxicity

Li‑Nan Zhang, Qi Wang, Xiao‑Hui Xian, Jie Qi, Li‑Zhe Liu, Wen‑Bin Li
Pages: 1521-1528
Published online on: 24 December 2018

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Article Open Access

Systematic screening and identification of novel psoriasis‑specific genes from the transcriptome of psoriasis‑like keratinocytes

Zhen Wang, Huaping Zheng, Hong Zhou, Nongyu Huang, Xiaoqiong Wei, Xiao Liu, Xiu Teng, Zhonglan Hu, Jun Zhang, Xikun Zhou, Wei Li, Jiong Li
Pages: 1529-1542
Published online on: 20 December 2018

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Article Open Access

MicroRNA‑219 overexpression serves a protective role during liver fibrosis by targeting tumor growth factor β receptor 2

Li Ma, Jian Ma, Hong‑Liang Ou
Pages: 1543-1550
Published online on: 21 December 2018

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Article Open Access

Luteolin suppresses lipopolysaccharide‑induced cardiomyocyte hypertrophy and autophagy in vitro

Xing Li, Jian Liu, Jianfeng Wang, Donghua Zhang
Pages: 1551-1560
Published online on: 02 January 2019

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Article Open Access

ATP synthase is required for male fertility and germ cell maturation in Drosophila testes

Jun Yu, Binghai Chen, Bo Zheng, Chen Qiao, Xia Chen, Yidan Yan, Xiaojin Luan, Bing Xie, Jiajia Liu, Cong Shen, Zeyu He, Xing Hu, Mingxi Liu, Hong Li, Qixiang Shao, Jie Fang
Pages: 1561-1570
Published online on: 08 January 2019

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Article Open Access

Identification of differentially expressed genes in MG63 osteosarcoma cells with drug‑resistance by microarray analysis

Rui Chen, Li‑Hong Huang, Yi‑Yao Gao, Jian‑Zeng Yang, Yan Wang
Pages: 1571-1580
Published online on: 18 December 2018

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Article Open Access

LncRNA BANCR participates in polycystic ovary syndrome by promoting cell apoptosis

Ruirui Yang, Jianmei Chen, Li Wang, Aijing Deng
Pages: 1581-1586
Published online on: 24 December 2018

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Article Open Access

High‑level SETD1B gene expression is associated with unfavorable prognosis in hepatocellular carcinoma

Dong Chen, Tieling Li, Cheng Wang, Guanglin Lei, Ruilan Wang, Zhaohai Wang, Linxiang Yu, Jin Yan, Peirui Zhang, Xiliang Wang, Shaogeng Zhang, Penghui Yang
Pages: 1587-1594
Published online on: 08 January 2019

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Article Open Access

Butyl stearate prolongs the drug release period of isoperidone‑loaded poly (lactic‑co‑glycolic acid) microspheres: In vitro and in vivo investigation

Fengying Sun, Changhui Yu, Ximing Liu, Dan Wang, Na Liu, Jiaxin Liu, Lesheng Teng, Youxin Li
Pages: 1595-1602
Published online on: 24 December 2018

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Article Open Access

Astragaloside IV prevents high glucose‑induced cell apoptosis and inflammatory reactions through inhibition of the JNK pathway in human umbilical vein endothelial cells

Liangzhen You, Zhaohui Fang, Guoming Shen, Qin Wang, Ying He, She Ye, Liu Wang, Mengjie Hu, Yixuan Lin, Mengmeng Liu, Aijuan Jiang
Pages: 1603-1612
Published online on: 03 January 2019

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Article Open Access

A thirteen‑gene set efficiently predicts the prognosis of glioblastoma

Huyin Yang, Luhao Jin, Xiaoyang Sun
Pages: 1613-1621
Published online on: 02 January 2019

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Article Open Access

Combination leflunomide and methotrexate impedes the recovery of liver fibrosis, partly through inhibition of myeloid cell admittance

Mengxin Lin, Ruyi Guo, Zhijun Su, Shaopeng Ke, Dawu Zeng
Pages: 1622-1628
Published online on: 04 January 2019

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Article Open Access

Metallic wear debris collected from patients induces apoptosis in rat primary osteoblasts via reactive oxygen species‑mediated mitochondrial dysfunction and endoplasmic reticulum stress

Fei Yang, Jian Tang, Kerong Dai, Yan Huang
Pages: 1629-1637
Published online on: 04 January 2019

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Article Open Access

Protective effect of dihydromyricetin revents fatty liver through nuclear factor‑κB/p53/B‑cell lymphoma 2‑associated X protein signaling pathways in a rat model

Lu Guo, Haifeng Zhang, Xiuping Yan
Pages: 1638-1644
Published online on: 20 December 2018

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Article Open Access

EVI‑1 acts as an oncogene and positively regulates calreticulin in breast cancer Retraction in /10.3892/mmr.2023.13112

Lei Wu, Tianyi Wang, Dongning He, Xiaoxi Li, Youhong Jiang
Pages: 1645-1653
Published online on: 24 December 2018

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Article Open Access

Novel 1,4‑naphthoquinone derivatives induce reactive oxygen species‑mediated apoptosis in liver cancer cells

Yue Wang, Ying‑Hua Luo, Xian‑Ji Piao, Gui‑Nan Shen, Ling‑Qi Meng, Yi Zhang, Jia‑Ru Wang, Jin‑Qian Li, Hao Wang, Wan‑Ting Xu, Yang Liu, Yu Zhang, Tong Zhang, Shi‑Nong Wang, Hu‑Nan Sun, Ying‑Hao Han, Mei‑Hua Jin, Yan‑Qing Zang, Dong‑Jie Zhang, Cheng‑Hao Jin
Pages: 1654-1664
Published online on: 21 December 2018

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Article Open Access

Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide‑induced lung injury

Wang Deng, Chang‑Yi Li, Jin Tong, Jing He, Yan Zhao, Dao‑Xin Wang
Pages: 1665-1677
Published online on: 02 January 2019

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Article Open Access

CCL18 enhances migration, invasion and EMT by binding CCR8 in bladder cancer cells

Xiaoqiang Liu, Xiangyun Xu, Wen Deng, Mingchuan Huang, Yanlong Wu, Zhengtao Zhou, Ke Zhu, Yibing Wang, Xinfu Cheng, Xiaochen Zhou, Luyao Chen, Yu Li, Gongxian Wang, Bin Fu
Pages: 1678-1686
Published online on: 24 December 2018

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Article Open Access

Low‑frequency pulsed electromagnetic field promotes functional recovery, reduces inflammation and oxidative stress, and enhances HSP70 expression following spinal cord injury

Chunyan Wang, Yang Liu, Yao Wang, Zhijian Wei, Dongmei Suo, Guangzhi Ning, Qiuli Wu, Shiqing Feng, Chunxiao Wan
Pages: 1687-1693
Published online on: 04 January 2019

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Article Open Access

Febuxostat inhibits TGF‑β1‑induced epithelial‑mesenchymal transition via downregulation of USAG‑1 expression in Madin‑Darby canine kidney cells in vitro

Linghong Lu, Jiajun Zhu, Yaqian Zhang, Yanxia Wang, Shu Zhang, Anzhou Xia
Pages: 1694-1704
Published online on: 02 January 2019

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Article Open Access

‘Heart development and morphogenesis’ is a novel pathway for human ovarian granulosa cell differentiation during long‑term in vitro cultivation‑a microarray approach

Wiesława Kranc, Maciej Brązert, Piotr Celichowski, Artur Bryja, Mariusz J. Nawrocki, Katarzyna Ożegowska, Maurycy Jankowski, Michal Jeseta, Leszek Pawelczyk, Andrzej Bręborowicz, Dominik Rachoń, Mariusz T. Skowroński, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty
Pages: 1705-1715
Published online on: 08 January 2019

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Article Open Access

Whole exome sequencing identifies hemizygous deletions in the UGT2B28 and USP17L2 genes in a three‑generation family with endometriosis

Hans M. Albertsen, Charoula Matalliotaki, Michail Matalliotakis, Maria I. Zervou, Ioannis Matalliotakis, Demetrios A. Spandidos, Rakesh Chettier, Kenneth Ward, George N. Goulielmos
Pages: 1716-1720
Published online on: 03 January 2019

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Article Open Access

Intermittent fasting increases the expressions of SODs and catalase in granule and polymorphic cells and enhances neuroblast dendrite complexity and maturation in the adult gerbil dentate gyrus

Ji Hyeon Ahn, Bich Na Shin, Minah Song, Hyunjung Kim, Joon Ha Park, Tae‑Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae‑Chul Lee, Jun‑Hwan Yong, Choong‑Hyun Lee, In Koo Hwang, Moo‑Ho Won, Yun Lyul Lee
Pages: 1721-1727
Published online on: 04 January 2019

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Article

Anti‑inflammatory effect of ciclamilast in an allergic model involving the expression of PDE4B

Xu‑Yang Zheng, Jun‑Chun Chen, Qiang‑Min Xie, Ji‑Qiang Chen, Hui‑Fang Tang
Pages: 1728-1738
Published online on: 02 January 2019

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Article

Function of Krüppel‑like factor 2 in the shear stress‑induced cell differentiation of endothelial progenitor cells to endothelial cells

Hai‑Rong Chu, Yu‑Cong Sun, Yu Gao, Xiu‑Mei Guan, Hong Yan, Xiao‑Dong Cui, Xiao‑Yun Zhang, Xin Li, Hong Li, Min Cheng
Pages: 1739-1746
Published online on: 03 January 2019

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Article

miR‑584‑5p regulates migration and invasion in non‑small cell lung cancer cell lines through regulation of MMP‑14

Tianmin Guo, Chenzhao Zheng, Zhigang Wang, Xifu Zheng
Pages: 1747-1752
Published online on: 03 January 2019

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Article

MicroRNA‑192 acts as a tumor suppressor in colon cancer and simvastatin activates miR‑192 to inhibit cancer cell growth

Xiao‑Fang Zheng, Kun‑Xiang Liu, Xin‑Mei Wang, Rui Zhang, Xin Li
Pages: 1753-1760
Published online on: 02 January 2019

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Article

Integrative analysis of shared genetic pathogenesis by obsessive‑compulsive and eating disorders

Cheng Xu, Hongbao Cao, Dongbai Liu
Pages: 1761-1766
Published online on: 17 December 2018

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Article

Galangin decreases p‑tau, Aβ42 and β‑secretase levels, and suppresses autophagy in okadaic acid‑induced PC12 cells via an Akt/GSK3β/mTOR signaling‑dependent mechanism

Liping Huang, Mingqin Lin, Xiaoqin Zhong, Hongyan Yang, Minzhen Deng
Pages: 1767-1774
Published online on: 04 January 2019

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Article

A novel dominant mutation in the SOX10 gene in a Chinese family with Waardenburg syndrome type II

Jing Ma, Zhen Zhang, Hong‑Chao Jiang, Hao Sun, Cheng Ming, Li‑Ping Zhao, Ying‑Qin Gao, Zheng‑Cai Li, Mei‑Hua Sun, Yang Xiao, Guo‑Li Wu, Tie‑Song Zhang, Biao Ruan
Pages: 1775-1780
Published online on: 03 January 2019

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Article

Dexamethasone protects against arsanilic acid‑induced rat vestibular dysfunction through the BDNF and JNK 1/2 signaling pathways

Yan Luo, Daogong Zhang, Yueling Chen, Zhongsheng Cao, Zhaomin Fan
Pages: 1781-1790
Published online on: 08 January 2019

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Article

Prenatal diagnosis of sex chromosome mosaicism with two marker chromosomes in three cell lines and a review of the literature

Jianli Zheng, Xiaoyu Yang, Haiyan Lu, Yongjuan Guan, Fangfang Yang, Mengjun Xu, Min Li, Xiuqing Ji, Yan Wang, Ping Hu, Yun Zhou
Pages: 1791-1796
Published online on: 24 December 2018

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Article

The mitochondrial transfer RNAAsp A7551G mutation may contribute to the clinical expression of deafness associated with the A1555G mutation in a pedigree with hearing impairment

Jing Zhang, Bo Lu, Wei‑Wei Xia, Bin Fang, Xiao‑Xia Ding, Guang‑Wei Hu
Pages: 1797-1802
Published online on: 24 December 2018

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Article

Aldosterone induces renal fibrosis by promoting HDAC1 expression, deacetylating H3K9 and inhibiting klotho transcription

Lingyun Lai, Ping Cheng, Minhua Yan, Yong Gu, Jun Xue
Pages: 1803-1808
Published online on: 20 December 2018

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Article

Standardized microwave extract of Sappan Lignum exerts anti‑inflammatory effects through inhibition of NF‑κB activation via regulation of heme oxygenase‑1 expression

Md Anisuzzaman Chowdhury, Moonbum Choi, Wonmin Ko, Hwan Lee, Sam Cheol Kim, Hyuncheol Oh, Eun‑Rhan Woo, Youn‑Chul Kim, Dong‑Sung Lee
Pages: 1809-1816
Published online on: 02 January 2019

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Article

Protective effects of metformin on lipopolysaccharide‑induced airway epithelial cell injury via NF‑κB signaling inhibition

Jiayang Sun, Niwen Huang, Wen Ma, Haiyan Zhou, Kefang Lai
Pages: 1817-1823
Published online on: 02 January 2019

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Article

The novel long non‑coding RNA PRNCR1‑2 is involved in breast cancer cell proliferation, migration, invasion and cell cycle progression

Danmei Pang, Qian Hu, Xiaoshan Lan, Yingxin Lin, Haibo Duan, Shuo Cao, Yaodong Lin, Litao Li, Feng Peng, Fengtao Pan
Pages: 1824-1832
Published online on: 24 December 2018

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Article

HBV infection suppresses the expression of inflammatory macrophage miR‑210

Feifei Li, Hongjun Bian, Wenwen Wang, Liping Ning, Miao Xu, Shuohuan Sun, Wanhua Ren, Chengyong Qin, Jianni Qi
Pages: 1833-1839
Published online on: 24 December 2018

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Article

Aryl hydrocarbon receptor activation modulates γδ intestinal intraepithelial lymphocytes and protects against ischemia/reperfusion injury in the murine small intestine

Zhicao Zhang, Aimin Pu, Min Yu, Weidong Xiao, Lihua Sun, Yujiao Cai, Hua Yang
Pages: 1840-1848
Published online on: 04 January 2019

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Article

miR‑34a derived from mesenchymal stem cells stimulates senescence in glioma cells by inducing DNA damage

Qun Li, Chengde Wang, Lin Cai, Jianglong Lu, Zhangzhang Zhu, Chunyong Wang, Zhipeng Su, Xianghe Lu
Pages: 1849-1857
Published online on: 24 December 2018

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Article

Tougu Xiaotong capsule exerts a therapeutic effect on knee osteoarthritis by regulating subchondral bone remodeling

Guangwen Wu, Jiahui Zhang, Wenlie Chen, Sainan Chen, Yunmei Huang, Ruhui Lin, Meiya Huang, Zuanfang Li, Liangpu Zheng, Xihai Li
Pages: 1858-1866
Published online on: 20 December 2018

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Article

Comparison of remote ischemic preconditioning and intermittent hypoxia training in fracture healing

Junjie Qiao, Meng Zhou, Zheng Li, Jie Ren, Guanghan Gao, Guanglei Cao, Huiliang Shen, Shibao Lu
Pages: 1867-1874
Published online on: 24 December 2018

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Article

microRNA‑577 inhibits cell proliferation and invasion in non‑small cell lung cancer by directly targeting homeobox A1

Lan Men, Dandan Nie, Haiying Nie
Pages: 1875-1882
Published online on: 02 January 2019

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Article

MicroRNA‑758 inhibits tumorous behavior in tongue squamous cell carcinoma by directly targeting metadherin Retraction in /10.3892/mmr.2023.13001

Yulan Zhang, Fuquan Zhao
Pages: 1883-1890
Published online on: 02 January 2019

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Article

Coculture with bone marrow‑derived mesenchymal stem cells attenuates inflammation and apoptosis in lipopolysaccharide‑stimulated alveolar epithelial cells via enhanced secretion of keratinocyte growth factor and angiopoietin‑1 modulating the Toll‑like receptor‑4 signal pathway

Xu‑Xin Chen, Lu Tang, Zhi‑Hai Han, Wen‑Jing Wang, Ji‑Guang Meng
Pages: 1891-1902
Published online on: 08 January 2019

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Article

MicroRNA‑744 suppresses cell proliferation and invasion of papillary thyroid cancer by directly targeting NOB1 Retraction in /10.3892/mmr.2023.13066

Haixia Liu, Jing Guo, Hongyan Chai, Xiangfeng Meng
Pages: 1903-1910
Published online on: 04 January 2019

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Article

Radix Sophorae Flavescentis inhibits proliferation and induces apoptosis of AGS human gastric cancer cells

Ji Sun Kim, Seung Jae Shin, Jung Nam Kim, Min Ji Kwon, Eun Yeong Lim, Yun Tai Kim, Hyungwoo Kim, Byung Joo Kim
Pages: 1911-1918
Published online on: 18 December 2018

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Article

Effects of various doses of atorvastatin on vascular endothelial cell apoptosis and autophagy in vitro

Wen‑Bo Zhao, Hui Fu, Fen Chang, Jing Liu, Jinlan Wang, Fang Li, Jing Zhao
Pages: 1919-1925
Published online on: 08 January 2019

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MicroRNA‑18b acts as an oncogene in gastric cancer by directly targeting Kruppel‑like factor 6 Retraction in /10.3892/mmr.2022.12916

Dongming Luo, Junqiang Chen, Shifeng Huang, Junyi Xu, Xuemin Song, Pengcheng Yu
Pages: 1926-1934
Published online on: 08 January 2019

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Article

NLRP3 inflammasome as the potential target mechanism and therapy in recurrent spontaneous abortions

Mudan Lu, Fengying Ma, Jianping Xiao, Lan Yang, Na Li, Daozhen Chen
Pages: 1935-1941
Published online on: 08 January 2019

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Article

Long non‑coding RNA DLX6‑AS1 is associated with malignant progression and promotes proliferation and invasion in esophageal squamous cell carcinoma

Mingchen Wang, Yuan Li, Yixin Yang, Xiaosa Liu, Mingxi Zang, Yuebai Li, Kunpeng Yang, Wanguang Yang, Shanfeng Zhang
Pages: 1942-1950
Published online on: 21 December 2018

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miR‑625‑5p suppresses inflammatory responses by targeting AKT2 in human bronchial epithelial cells

Fen-Hong Qian, Xia Deng, Qiong-Xin Zhuang, Bin Wei, Dan-Dan Zheng
Pages: 1951-1957
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Article

Kaempferol inhibits multiple pathways involved in the secretion of inflammatory mediators from LPS‑induced rat intestinal microvascular endothelial cells

Yifei Bian, Ping Liu, Jia Zhong, Yusheng Hu, Yingsai Fan, Shen Zhuang, Zhongjie Liu
Pages: 1958-1964
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Inhibition of microRNA‑492 attenuates cell proliferation and invasion in retinoblastoma via directly targeting LATS2

Zhiqun Sun, Aimei Zhang, Liming Zhang
Pages: 1965-1971
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Article

Bergapten induces G1 arrest of non‑small cell lung cancer cells, associated with the p53‑mediated cascade

Shyh‑Ren Chiang, Chun‑Shiang Lin, Hui‑Han Lin, Pei‑Chen Shieh, Shao‑Hsuan Kao
Pages: 1972-1978
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[Corrigendum] Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression

Zanjing Zhai, Xinhua Qu, Haowei Li, Zhengxiao Ouyang, Wei Yan, Guangwang Liu, Xuqiang Liu, Qiming Fan, Tingting Tang, Kerong Dai, An Qin
Pages: 1979-1979
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Review

Investigational drugs in HIV: Pros and cons of entry and fusion inhibitors (Review)

Emmanuele Venanzi Rullo, Manuela Ceccarelli, Fabrizio Condorelli, Alessio Facciolà, Giuseppa Visalli, Francesco D'Aleo, Ivana Paolucci, Bruno Cacopardo, Marilia Rita Pinzone, Michele Di Rosa, Giuseppe Nunnari, Giovanni F. Pellicanò
Pages: 1987-1995
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Postnatal changes in constitutive cyclooxygenase‑2 expression in the mice hippocampus and its function in synaptic plasticity

Hyo Young Jung, Dae Young Yoo, Sung Min Nam, Jong Whi Kim, Woosuk Kim, Hyun Jung Kwon, Kwon Young Lee, Jung Hoon Choi, Dae Won Kim, Yeo Sung Yoon, Je Kyung Seong, In Koo Hwang
Pages: 1996-2004
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Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Aβ25‑35‑treated PC12 cells by inhibiting the p38 MAPK signaling pathway

Yuhong Ma, Li Xiong
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Identification of critical genes associated with spinal cord injury based on the gene expression profile of spinal cord tissues from trkB.T1 knockout mice

Li Wei, Fei He, Wen Zhang, Wenhua Chen, Bo Yu
Pages: 2013-2020
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Escherichia coli promotes DSS‑induced murine colitis recovery through activation of the TLR4/NF‑κB signaling pathway

Jiabao Lu, Boye Dong, Ailan Chen, Feng He, Baifu Peng, Zixin Wu, Jie Cao, Wanglin Li
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Identification of differentially expressed genes and enriched pathways in lung cancer using bioinformatics analysis

Tingting Long, Zijing Liu, Xing Zhou, Shuang Yu, Hui Tian, Yixi Bao
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Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumor

Xiaofu Wang, Pan Song, Chuiguo Huang, Naijun Yuan, Xinghua Zhao, Changbao Xu
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LncRNA‑NEF is involved the regulation of gastric carcinoma cell proliferation by targeting RUNX1

Xue Wang, Xue Jiang, Li Zhou, Zhuo Wang, He Huang, Mengqiao Wang
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Curculigoside exerts significant anti‑arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF‑κB signaling pathway

Shirui Tan, Jian Xu, Aiyun Lai, Ruomei Cui, Ru Bai, Shu Li, Wei Liang, Guofang Zhang, Shaoquan Jiang, Shuang Liu, Mai Zheng, Wei Wang
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Identification of key genes and pathways involved in microsatellite instability in colorectal cancer

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Expression of flTF and asTF splice variants in various cell strains and tissues

Lili Pan, Yang Yu, Miaomei Yu, Shuang Yao, Qinfeng Mu, Guanghua Luo, Ning Xu
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Anti‑inflammatory effects of Dendropanax morbifera in lipopolysaccharide‑stimulated RAW264.7 macrophages and in an animal model of atopic dermatitis

Gang‑Sik Choo, Dong‑Pyo Lim, Sae‑Man Kim, Eun‑Seon Yoo, Sung‑Hyun Kim, Chang‑Hyun Kim, Joong‑Seok Woo, Hyeong‑Jin Kim, Ji‑Youn Jung
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Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells

Aldo F. Clemente‑Soto, Enrique Salas‑Vidal, Cesar Milan‑Pacheco, Jessica Nayelli Sánchez‑Carranza, Oscar Peralta‑Zaragoza, Leticia González‑Maya
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Mechanical force promotes the proliferation and extracellular matrix synthesis of human gingival fibroblasts cultured on 3D PLGA scaffolds via TGF‑β expression

Lan Nan, Yi Zheng, Ni Liao, Songze Li, Yao Wang, Zhixing Chen, Liying Wei, Shuang Zhao, Shuixue Mo
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HepaCAM inhibits cell proliferation and invasion in prostate cancer by suppressing nuclear translocation of the androgen receptor via its cytoplasmic domain Corrigendum in /10.3892/mmr.2022.12746

Qingfu Deng, Li Luo, Zhen Quan, Nanjing Liu, Zhongbo Du, Wei Sun, Chunli Luo, Xiaohou Wu
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Huan Zhou, Shun Tan, Hong Li, Xiangtao Lin
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Haiyan Zhang, Guang Li, Xiugui Sheng, Shiqian Zhang
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Nan Niu, Zihua Li, Mingxing Zhu, Hongli Sun, Jihui Yang, Shimei Xu, Wei Zhao, Rong Song
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Long noncoding RNA GAS5 promotes apoptosis in primary nucleus pulposus cells derived from the human intervertebral disc via Bcl‑2 downregulation and caspase‑3 upregulation

Yifeng Wang, Qingxin Song, Xuan Huang, Zhi Chen, Fan Zhang, Kun Wang, Guofeng Huang, Hongxing Shen
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Hongyu Liu, Min Wang, Na Liang, Lianyue Guan
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NLRP3 inflammasome inactivation driven by miR‑223‑3p reduces tumor growth and increases anticancer immunity in breast cancer

Liping Zhang, Hongzhi Li, Yuwei Zang, Feng Wang
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Effects of storage culture media, temperature and duration on human adipose‑derived stem cell viability for clinical use

Yin‑Di Wu, Meng Li, Xuan Liao, Sheng‑Hong Li, Jian‑Xin Yan, Lei Fan, Wen‑Li She, Jian‑Xin Song, Hong‑Wei Liu
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Zhang‑Yi Li, Zhi‑Xing Wang, Chang‑Chun Li
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Yuanyi Zuo, Jun Hu, Xuehua Xu, Xiangting Gao, Yun Wang, Shaohua Zhu
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Genetic polymorphisms of melatonin receptors 1A and 1B may result in disordered lipid metabolism in obese patients with polycystic ovary syndrome

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Lai‑Te Chen, Chen‑Yang Jiang
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Piperazine ferulate ameliorates the development of diabetic nephropathy by regulating endothelial nitric oxide synthase

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Scutellaria barbata polysaccharides inhibit tumor growth and affect the serum proteomic profiling of hepatoma H22‑bearing mice

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Ru‑Jian Zhou, Hui‑Zeng Lv
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The estrogen‑like protective effect of Lycium barbarum polysaccharides in reducing oxidative stress on myocardial cells from ovariectomized rats

Ning Yu, Nan Song, Chun Ying Liu, Guan Lin Yang
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Sodium houttuyfonate inhibits LPS‑induced mastitis in mice via the NF‑κB signalling pathway

Pei Liu, Chao Yang, Sihui Lin, Gan Zhao, Tao Zhang, Shuai Guo, Kangfeng Jiang, Haichong Wu, Changwei Qiu, Mengyao Guo, Ganzhen Deng
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Cx32 mediates cisplatin resistance in human ovarian cancer cells by affecting drug efflux transporter expression and activating the EGFR‑Akt pathway

Yu Zhang, Liang Tao, Li‑Xia Fan, Kun Huang, Hui‑Min Luo, Hui Ge, Xiyan Wang, Qin Wang
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ZEB1 promotes tumorigenesis and metastasis in hepatocellular carcinoma by regulating the expression of vimentin

Yue Qin, Jingxi Yu, Ming Zhang, Faxiang Qin, Xiong Lan
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β‑elemene inhibits oxygen‑induced retinal neovascularization via promoting miR‑27a and reducing VEGF expression

Weilai Zhang, Lei Chen, Jin Geng, Limin Liu, Li Xu
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IL‑6 prevents CXCL8‑induced stimulation of EpCAM expression in ovarian cancer cells

Lucyna Kapka‑Skrzypczak, Sylwia Popek, Krzysztof Sawicki, Bartłomiej Drop, Magdalena Czajka, Barbara Jodłowska‑Jędrych, Magdalena Matysiak‑Kucharek, Dominika Furman‑Toczek, Martyna Zagórska‑Dziok, Marcin Kruszewski
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Expression and functional analysis of Brucella outer membrane protein 25 in recombinant goat pox virus

Zhihua Sun, Laizhen Liu, Hui Zhang, Youwen Li, Feng Wei, Zhiqiang Li, Pengyan Wang, Qiang Fu, Yan Ren, Yu Zhang, Zhiru Guo, Chuangfu Chen
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Article

Values of applying white blood cell counts in the prognostic evaluation of resectable colorectal cancer

Jing Wu, Xin‑Xin Ge, Wenyu Zhu, Qiaoming Zhi, Meng‑Dan Xu, Weiming Duan, Kai Chen, Fei‑Ran Gong, Min Tao, Liu‑Mei Shou, Meng‑Yao Wu, Wen‑Jie Wang
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Estradiol induces cell proliferation in MCF‑7 mammospheres through HER2/COX‑2

Chin‑Hu Wu, Hui‑Yu Chuang, Chiu‑Lin Wang, Chia‑Yi Hsu, Cheng‑Yu Long, Tsung‑Hua Hsieh, Eing‑Mei Tsai
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Global pathway view analysis of microRNA clusters in myasthenia gravis

Chunrui Bo, Jianjian Wang, Huixue Zhang, Yuze Cao, Xiaoyu Lu, Tianfeng Wang, Yu Wang, Shuang Li, Xiaotong Kong, Xuesong Sun, Zhaojun Liu, Shangwei Ning, Lihua Wang
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miRNA‑135a regulates Hut78 cell proliferation via the GATA‑3/TOX signaling pathway

Hong Wei, Ruifeng Liu, Xvli Guo, Yin Zhou, Bo Sun, Jialin Wang
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Screening and preliminary validation of T lymphocyte immunoregulation‑associated long non‑coding RNAs in diabetic foot ulcers

Shujuan Xu, Xiaoyu Weng, Ya Wang, Dalun Lv, Meihong Zeng, Fen Zhao, Yu Sun
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Expression and effects of leukemia inhibitory factor on nucleus pulposus degeneration

Qiang Xiao, Ji‑Huan Zeng, Hao Zhou, Quan‑He Qiu, Bo Ke, Liang Deng, Zhen‑Ming Hu, Jeffrey Roh, Min Dai
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Altered expression of genes involved in brain energy metabolism as adaptive responses in rats exposed to chronic variable stress; changes in cortical level of glucogenic and neuroactive amino acids

Mariola Herbet, Dorota Natorska‑Chomicka, Agnieszka Korga, Marta Ostrowska, Magdalena Izdebska, Monika Gawrońska‑Grzywacz, Iwona Piątkowska‑Chmiel, Kamil Pawłowski, Brygida Ślaska, Ewa Poleszak, Jarosław Dudka
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Ulinastatin inhibits apoptosis induced by serum deprivation in mesenchymal stem cells

Linhui Shi, Longqiang Ye, Panpan Liu, Danqin Liu, Gongjie Ye, Jiahong Chen, Zhouzhou Dong
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Article

miR‑671‑3p is downregulated in non‑small cell lung cancer and inhibits cancer progression by directly targeting CCND2

Yuanshan Yao, Yinjie Zhou, Xiaojun Fu
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Expression of S100A8 is induced by interleukin‑1α in TR146 epithelial cells through a mechanism involving CCAAT/enhancer binding protein β

Mingqun Qin, Yantao Zou, Kanghua Zhong, Yong Guo, Xianqiong Zou
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Participation of the AngII/TRPC6/NFAT axis in the pathogenesis of podocyte injury in rats with type 2 diabetes

Ruixia Ma, Yan Xu, Hanyan Zhou, Di Zhang, Dandan Yao, Limin Song, Yuan Liu
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MicroRNA‑601 serves as a potential tumor suppressor in hepatocellular carcinoma by directly targeting PIK3R3 Retraction in /10.3892/mmr.2022.12923

Yanan Song, Saifei He, Juhua Zhuang, Guoyu Wang, Jing Ni, Suiliang Zhang, Ying Ye, Wei Xia
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β‑ecdysterone protects against apoptosis by promoting autophagy in nucleus pulposus cells and ameliorates disc degeneration

Feng Wen, Jun Yu, Cheng‑Jian He, Zhi‑Wen Zhang, Ao‑Fei Yang
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Endothelial progenitor cell impairment mediated vasodilation dysfunction via diminishing nitric oxide production in postmenopausal females

Wan‑Zhou Wu, Da‑Jun Hu, Zhen‑Yu Wang, Long‑Sheng Liao, Chuan‑Chang Li
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[Corrigendum] Genome‑wide DNA methylation analysis of uterosacral ligaments in women with pelvic organ prolapse

Lifang Zhang, Ping Zheng, Aihong Duan, Yan Hao, Chang Lu, Dan Lu
Pages: 2458-2458
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Yan Shi, Shu-Ai Hou
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Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
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Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

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Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

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Published online on: 31 October 2025

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Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

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Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

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Article Number: 18
Published online on: 29 October 2025

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Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
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Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
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Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

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Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

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Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
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Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

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Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

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Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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