|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ciombor KK, Wu C and Goldberg RM: Recent
therapeutic advances in the treatment of colorectal cancer. Annu
Rev Med. 66:83–95. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kobe B and Deisenhofer J: Crystal
structure of porcine ribonuclease inhibitor, a protein with
leucine-rich repeats. Nature. 366:751–756. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
McEwan PA, Scott PG, Bishop PN and Bella
J: Structural correlations in the family of small leucine-rich
repeat proteins and proteoglycans. J Struct Biol. 155:294–305.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Datta D, Samanta A, Dasgupta S and Pathak
T: 3′-Oxo-, amino-, thio- and sulfone-acetic acid modified
thymidines: Effect of increased acidity on ribonuclease A
inhibition. Bioorg Med Chem. 21:4634–4645. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Dickson KA, Haigis MC and Raines RT:
Ribonuclease inhibitor: Structure and function. Prog Nucleic Acid
Res Mol Biol. 80:349–374. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Pan X, Xiong D, Yao X, Xin Y, Zhang L and
Chen J: Up-regulating ribonuclease inhibitor inhibited
epithelial-to-mesenchymal transition and metastasis in murine
melanoma cells. Int J Biochem Cell Biol. 44:998–1008. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yao X, Li D, Xiong DM, Li L, Jiang R and
Chen JX: A novel role of ribonuclease inhibitor in regulation of
epithelial-to-mesenchymal transition and ILK signaling pathway in
bladder cancer cells. Cell Tissue Res. 353:409–423. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chen JX, Gao Y, Liu JW, Tian YX, Zhao J
and Cui XY: Antitumor effects of human ribonuclease inhibitor gene
transfected on B16 melanoma cells. Int J Biochem Cell Biol.
37:1219–1231. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Tian YX, Wang DM and Cui XY: Analysis of
gene expression of ribonuclease inhibitor in human breast cancer
tissue. Ai Zheng. 23:269–272. 2004.(In Chinese). PubMed/NCBI
|
|
12
|
Tang Y, Liu P, Tian Y, Xu Y, Ren F, Cui X
and Fan J: Overexpression of ribonuclease inhibitor defines good
prognosis and suppresses proliferation and metastasis in human
colorectal cancer cells via PI3K/AKT pathway. Clin Transl Oncol.
17:306–313. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Degtyarev M, De Mazière A, Orr C, Lin J,
Lee BB, Tien JY, Prior WW, van Dijk S, Wu H, Gray DC, et al: Akt
inhibition promotes autophagy and sensitizes PTEN-null tumors to
lysosomotropic agents. J Cell Biol. 183:101–116. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kabeya Y, Mizushima N, Ueno T, Yamamoto A,
Kirisako T, Noda T, Kominami E, Ohsumi Y and Yoshimori T: LC3, a
mammalian homologue of yeast Apg8p, is localized in autophagosome
membranes after processing. EMBO J. 19:5720–5728. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Mizushima N, Levine B, Cuervo AM and
Klionsky DJ: Autophagy fights disease through cellular
self-digestion. Nature. 451:1069–1075. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
White E and DiPaola RS: The double-edged
sword of autophagy modulation in cancer. Clin Cancer Res.
15:5308–5316. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ellington AA, Berhow M and Singletary KW:
Induction of macroautophagy in human colon cancer cells by soybean
B-group triterpenoid saponins. Carcinogenesis. 26:159–167. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Liang C, Feng P, Ku B, Dotan I, Canaani D,
Oh BH and Jung JU: Autophagic and tumour suppressor activity of a
novel Beclin1-binding protein UVRAG. Nat Cell Biol. 8:688–699.
2006. View
Article : Google Scholar : PubMed/NCBI
|
|
19
|
Cheng Y, Ren X, Zhang Y, Patel R, Sharma
A, Wu H, Robertson GP, Yan L, Rubin E and Yang JM: eEF-2 kinase
dictates cross-talk between autophagy and apoptosis induced by Akt
Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor
MK-2206. Cancer Res. 71:2654–2663. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R
and Chen J: Interplay between intergrin-linked kinase and
ribonuclease inhibitor affects growth and metastasis of bladder
cancer through signaling ILK pathways. J Exp Clin Cancer Res.
35:1302016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Ji S, Lin W, Wang L, Ni Z, Jin F, Zha X
and Fei G: Combined targeting of mTOR and Akt using rapamycin and
MK-2206 in the treatment of tuberous sclerosis complex. J Cancer.
8:555–562. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Pizzo E, Sarcinelli C, Sheng J, Fusco S,
Formiggini F, Netti P, Yu W, D'Alessio G and Hu GF:
Ribonuclease/angiogenin inhibitor 1 regulates stress-induced
subcellular localization of angiogenin to control growth and
survival. J Cell Sci. 126:4308–4319. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhou JH, Tang XY, Zhao R, Wang H and Xia
J: Effects of ribonuclease inhibitor on apoptosis and invasion of
human breast cancer MDA-MB-231 cells. Xi Bao Yu Fen Zi Mian Yi Xue
Za Zhi. 28:260–264. 2012.(In Chinese). PubMed/NCBI
|
|
24
|
Han K, Kim J and Choi M: Autophagy
mediates phase transitions from cell death to life. Heliyon.
1:e000272015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Carroll RG and Martin SJ: Autophagy in
multiple myeloma: What makes you stronger can also kill you. Cancer
Cell. 23:425–426. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Dickson KA, Kang DK, Kwon YS, Kim JC,
Leland PA, Kim BM, Chang SI and Raines RT: Ribonuclease inhibitor
regulates neovascularization by human angiogenin. Biochemistry.
48:3804–3806. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Peng Y, Li L, Huang M, Duan C, Zhang L and
Chen J: Angiogenin interacts with ribonuclease inhibitor regulating
PI3K/AKT/mTOR signaling pathway in bladder cancer cells. Cell
Signal. 26:2782–2792. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Liu JL, Chang KC, Lo CC, Chu PY and Liu
CH: Expression of autophagy-related protein Beclin-1 in malignant
canine mammary tumors. BMC Vet Res. 9:752013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Young PG, Passalacqua MJ, Chappell K,
Llinas RJ and Bartel B: A facile forward-genetic screen for
Arabidopsis autophagy mutants reveals twenty-one loss-of-function
mutations disrupting six ATG genes. Autophagy. 1–19. 2019.
View Article : Google Scholar
|
|
30
|
Nishida Y, Arakawa S, Fujitani K,
Yamaguchi H, Mizuta T, Kanaseki T, Komatsu M, Otsu K, Tsujimoto Y
and Shimizu S: Discovery of Atg5/Atg7-independent alternative
macroautophagy. Nature. 461:654–658. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Qi S, Kim DJ, Stjepanovic G and Hurley JH:
Structure of the human Atg13-Atg101 HORMA heterodimer: An
interaction hub within the ULK1 complex. Structure. 23:1848–1857.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Levine B: Cell biology: Autophagy and
cancer. Nature. 446:745–747. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
33
|
Liu M, Zhao G, Zhang D, An W, Lai H, Li X,
Cao S and Lin X: Active fraction of clove induces apoptosis via
PI3K/Akt/mTOR-mediated autophagy in human colorectal cancer HCT-116
cells. Int J Oncol. 53:1363–1373. 2018.PubMed/NCBI
|
|
34
|
Yang L, Liu Y, Wang M, Qian Y, Dai X, Zhu
Y, Chen J, Guo S and Hisamitsu T: Celastrus orbiculatus extract
triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in
human colorectal cancer cells. Oncol Lett. 12:3771–3778. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Fan XJ, Wang Y, Wang L and Zhu M:
Salidroside induces apoptosis and autophagy in human colorectal
cancer cells through inhibition of PI3K/Akt/mTOR pathway. Oncol
Rep. 36:3559–3567. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Kim J, Kundu M, Viollet B and Guan KL:
AMPK and mTOR regulate autophagy through direct phosphorylation of
Ulk1. Nat Cell Biol. 13:132–141. 2011. View
Article : Google Scholar : PubMed/NCBI
|
|
37
|
Egan DF, Shackelford DB, Mihaylova MM,
Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor
R, et al: Phosphorylation of ULK1 (hATG1) by AMP-activated protein
kinase connects energy sensing to mitophagy. Science. 331:456–461.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Lin Y, Kuang W, Wu B, Xie C, Liu C and Tu
Z: IL-12 induces autophagy in human breast cancer cells through
AMPK and the PI3K/Akt pathway. Mol Med Rep. 16:4113–4118. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Zhou X, Yue GG, Chan AM, Tsui SK, Fung KP,
Sun H, Pu J and Lau CB: Eriocalyxin B, a novel autophagy inducer,
exerts anti-tumor activity through the suppression of
Akt/mTOR/p70S6K signaling pathway in breast cancer. Biochem
Pharmacol. 142:58–70. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Mizushima N and Komatsu M: Autophagy:
Renovation of cells and tissues. Cell. 147:728–741. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Green DR and Levine B: To be or not to be?
How selective autophagy and cell death govern cell fate. Cell.
157:65–75. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Fujiwara K, Iwado E, Mills GB, Sawaya R,
Kondo S and Kondo Y: Akt inhibitor shows anticancer and
radiosensitizing effects in malignant glioma cells by inducing
autophagy. Int J Oncol. 31:753–760. 2007.PubMed/NCBI
|
