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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-2019 Volume 19 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

LETM1 is required for mitochondrial homeostasis and cellular viability (Review)

Yuwen Li, Quangdon Tran, Robin Shrestha, Longzhen Piao, Sungjin Park, Jisoo Park, Jongsun Park
Pages: 3367-3375
Published online on: 15 March 2019

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Article Open Access

Identification of exosomal and non‑exosomal microRNAs associated with the drug resistance of ovarian cancer

Yiwen Feng, Wenzhao Hang, Zhenyu Sang, Shuangdi Li, Wei Xu, Yi Miao, Xiaowei Xi, Qian Huang
Pages: 3376-3392
Published online on: 05 March 2019

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Article Open Access

MicroRNA‑4530 suppresses cell proliferation and induces apoptosis by targeting RASA1 in human umbilical vein endothelial cells

Li Jing, Hong Li, Tao Zhang, Jianxin Lu, Lianjin Zhong
Pages: 3393-3402
Published online on: 01 March 2019

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Article Open Access

Effect of miR‑145 on gastric cancer cells

Jia Wang, Zheng Sun, Shihai Yan, Feng Gao
Pages: 3403-3410
Published online on: 06 March 2019

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Article Open Access

Construction and dissection of the ceRNA‑ceRNA network reveals critical modules in depression

Yan Lang, Jingchao Zhang, Zheng Yuan
Pages: 3411-3420
Published online on: 05 March 2019

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Article Open Access

Long noncoding RNA expression profile and functional analysis in psoriasis

Jianjun Yan, Jie Song, Meng Qiao, Xintong Zhao, Ronghua Li, Jian Jiao, Qing Sun
Pages: 3421-3430
Published online on: 27 February 2019

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Article Open Access

ACC1 is overexpressed in liver cancers and contributes to the proliferation of human hepatoma Hep G2 cells and the rat liver cell line BRL 3A

Bingyu Ye, Li Yin, Qiwen Wang, Cunshuan Xu
Pages: 3431-3440
Published online on: 27 February 2019

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Article Open Access

Clinical diagnosis and genetic counseling of atypical ataxia‑telangiectasia in a Chinese family

Jiangxia Cao, Ruiqin Shen, Wenqian Zhang, Bing Mao, Qirong Shi, Rui Zhou, Zijing Liu, Bing Zeng, Xiaoling Chen, Cai Zhang, Min Lu, Peng Han, Jing Wu, Aifen Zhou, Xuemei Tan
Pages: 3441-3448
Published online on: 27 February 2019

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Article Open Access

Protective effects of carbon monoxide releasing molecule‑2 on pancreatic function in septic mice

Yishu Liu, Xu Wang, Xiaohan Xu, Weiting Qin, Bingwei Sun
Pages: 3449-3458
Published online on: 18 March 2019

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Article Open Access

c‑Jun/Ap‑1 is upregulated in an Ang II‑induced abdominal aortic aneurysm formation model and mediates Chop expression in mouse aortic smooth muscle cells

Dating Sun, Mingxi Zhang, Yuanyuan Li, Shuai Mei, Jin Qin, Jiangtao Yan
Pages: 3459-3468
Published online on: 12 March 2019

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Article Open Access

ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis

Luna Ge, Yazhou Cui, Baoyan Liu, Xiaoli Yin, Jingxiang Pang, Jinxiang Han
Pages: 3469-3476
Published online on: 01 March 2019

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Article Open Access

Keratin 6A gene silencing suppresses cell invasion and metastasis of nasopharyngeal carcinoma via the β‑catenin cascade

Chuanjun Chen, Huiguo Shan
Pages: 3477-3484
Published online on: 18 March 2019

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Article Open Access

Diagnostic and prognostic value of CEP55 in clear cell renal cell carcinoma as determined by bioinformatics analysis

Libin Zhou, Shibo Liu, Xing Li, Min Yin, Sheng Li, Huimin Long
Pages: 3485-3496
Published online on: 15 March 2019

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Article Open Access

Enhanced sensitivity of capture IgE‑ELISA based on a recombinant Der f 1/2 fusion protein for the detection of IgE antibodies targeting house dust mite allergens

Zhen Zhang, Zelang Cai, Yibo Hou, Jiayun Hu, Yongshen He, Jiajie Chen, Kunmei Ji
Pages: 3497-3504
Published online on: 18 March 2019

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Article Open Access

TGF‑β1 promotes the osteoinduction of human osteoblasts via the PI3K/AKT/mTOR/S6K1 signalling pathway

Zhaodong Zhang, Xiuzhi Zhang, Dewei Zhao, Baoyi Liu, Benjie Wang, Weiting Yu, Junlei Li, Xiaobing Yu, Fang Cao, Guoshuang Zheng, Yao Zhang, Yupeng Liu
Pages: 3505-3518
Published online on: 18 March 2019

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Article Open Access

Overexpression of ribonuclease inhibitor induces autophagy in human colorectal cancer cells via the Akt/mTOR/ULK1 pathway

Ying Tang, Feng Ren, Xi Cong, Ying Kong, Yuxiang Tian, Yuefei Xu, Jianhui Fan
Pages: 3519-3526
Published online on: 14 March 2019

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Article Open Access

MicroRNA‑1 downregulation induced by carvedilol protects cardiomyocytes against apoptosis by targeting heat shock protein 60

Yingying Hu, Xi Chen, Xina Li, Zhange Li, Hongtao Diao, Lu Liu, Jia Zhang, Jin Ju, Lin Wen, Xin Liu, Zhenwei Pan, Chaoqian Xu, Xin Hai, Yong Zhang
Pages: 3527-3536
Published online on: 14 March 2019

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Article Open Access

Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway

Shanshan Zhu, Tao Wang, Fei Luo, Huawen Li, Qing Jia, Taiping He, Hongfu Wu, Tangbin Zou
Pages: 3537-3547
Published online on: 14 March 2019

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Article Open Access

Rhizoma Paridis saponins ameliorates hepatic fibrosis in rats by downregulating expression of angiogenesis‑associated growth factors

Yanquan Han, Lingyu Pan, Shan Ran, Yan Song, Fang‑Fang Sun, Yong‑Zhong Wang, Yan Hong
Pages: 3548-3554
Published online on: 05 March 2019

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Article Open Access

Estrogen receptor β suppresses inflammation and the progression of prostate cancer

Long Xiao, Yaohui Luo, Rongfen Tai, Ningnan Zhang
Pages: 3555-3563
Published online on: 06 March 2019

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Article Open Access

Expression analysis of transfer RNA‑derived fragments in the blood of patients with moyamoya disease: A preliminary study

Chengjun Wang, Meng Zhao, Jia Wang, Dong Zhang, Shuo Wang, Jizong Zhao
Pages: 3564-3574
Published online on: 14 March 2019

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Article Open Access

miR‑145 suppresses ovarian cancer progression via modulation of cell growth and invasion by targeting CCND2 and E2F3

Minhui Hua, Yongwei Qin, Meihong Sheng, Xiaopeng Cui, Weiguan Chen, Jianxin Zhong, Junming Yan, Yan Chen
Pages: 3575-3583
Published online on: 05 March 2019

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Article Open Access

A new combination of transcription factors increases the harvesting efficiency of pacemaker‑like cells

Jian Zhang, Congxin Huang
Pages: 3584-3592
Published online on: 06 March 2019

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Article Open Access

Dose and drug changes in chronic lymphocytic leukemia cell response in vitro: A comparison of standard therapy regimens with two novel cyclin‑dependent kinase inhibitors

Małgorzata Kubczak, Aleksandra Szustka, Jerzy Z. Błoński, Tomaš Gucký, Małgorzata Misiewicz, Vladmir Krystof, Paweł Robak, Małgorzata Rogalińska
Pages: 3593-3603
Published online on: 05 March 2019

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Article Open Access

miR‑512‑5p suppresses proliferation, migration and invasion, and induces apoptosis in non‑small cell lung cancer cells by targeting ETS1

Bin Cao, Sheng Tan, Huijuan Tang, Yihui Chen, Peng Shu
Pages: 3604-3614
Published online on: 14 March 2019

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Article Open Access

LncRNA AWPPH promotes the proliferation, migration and invasion of ovarian carcinoma cells via activation of the Wnt/β‑catenin signaling pathway

Guangyu Yu, Wenshuang Wang, Junfeng Deng, Shaohua Dong
Pages: 3615-3621
Published online on: 14 March 2019

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Article Open Access

Spironolactone dose‑dependently alleviates the calcification of aortic rings cultured in hyperphosphatemic medium with or without hyperglycemia by suppressing phenotypic transition of VSMCs through downregulation of Pit‑1

Ping Wang, Zhengli Quan, Dingshi Luo, Wangshan Chen, Dan Peng
Pages: 3622-3632
Published online on: 15 March 2019

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Article Open Access

Ginsenoside Rb1 attenuates intestinal ischemia/reperfusion‑induced inflammation and oxidative stress via activation of the PI3K/Akt/Nrf2 signaling pathway

Sufang Chen, Xiang Li, Yanling Wang, Panwei Mu, Chaojin Chen, Pinjie Huang, Dezhao Liu
Pages: 3633-3641
Published online on: 12 March 2019

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Article Open Access

The antitumor function of arctigenin in human retinoblastoma cells is mediated by jagged‑1

Ning Ke, Qing Liu, Lianhong Pi, Jing Fang, Lin Chen, Xinke Chen
Pages: 3642-3648
Published online on: 14 March 2019

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Article Open Access

Activation of the ERK/Creb/Bcl‑2 pathway protects periodontal ligament stem cells against hydrogen peroxide‑induced oxidative stress

Xiaohui Fu, Yimiao Feng, Bingyi Shao, Yanzhen Zhang
Pages: 3649-3657
Published online on: 14 March 2019

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Article Open Access

Knockdown of serpin peptidase inhibitor clade C member 1 inhibits the growth of nasopharyngeal carcinoma cells

Jin Xu, Yin Ying, Gaoyun Xiong, Liqin Lai, Qingliang Wang, Yue Yang
Pages: 3658-3666
Published online on: 14 March 2019

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Article Open Access

MicroRNA‑124 suppresses cell proliferation and invasion of triple negative breast cancer cells by targeting STAT3

Pengfei Shi, Cheng Chen, Xiang Li, Zhanjie Wei, Zhimin Liu, Yongjun Liu
Pages: 3667-3675
Published online on: 15 March 2019

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Article Open Access

Vitamin K2 stimulates MC3T3‑E1 osteoblast differentiation and mineralization through autophagy induction

Weiwei Li, Shaokun Zhang, Jie Liu, Yongyi Liu, Qingwei Liang
Pages: 3676-3684
Published online on: 15 March 2019

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Article Open Access

Prognostic role of Tif1γ expression and circulating tumor cells in patients with breast cancer

Fengfeng Cai, Lu Cai, Zhuchao Zhou, Xin Pan, Minghong Wang, Su Chen, Manuel Antonio Falar Luis, Chunmei Cen, Ewelina Biskup
Pages: 3685-3695
Published online on: 14 March 2019

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Article Open Access

SDF‑1/CXCR4 induces epithelial‑mesenchymal transition through activation of the Wnt/β‑catenin signaling pathway in rat chronic allograft nephropathy

Hao Tang, Yue Xu, Zijian Zhang, Song Zeng, Wenbo Dong, Wenjiao Jiao, Xiaopeng Hu
Pages: 3696-3706
Published online on: 15 March 2019

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Article Open Access

1,25‑Dihydroxy‑Vitamin D3 induces macrophage polarization to M2 by upregulating T‑cell Ig‑mucin‑3 expression

Shuyu Liang, Jinzhen Cai, Yani Li, Rui Yang
Pages: 3707-3713
Published online on: 15 March 2019

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Article Open Access

circEIF4G2 modulates the malignant features of cervical cancer via the miR‑218/HOXA1 pathway

Yifan Mao, Liya Zhang, Yuan Li
Pages: 3714-3722
Published online on: 14 March 2019

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Article Open Access

Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in rats

Wei‑Dong Li, Jin‑Rong Xia, Yan‑Shu Lian
Pages: 3723-3731
Published online on: 14 March 2019

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Article Open Access

Calcitonin gene‑related peptide regulates FOSL2 expression and cell proliferation of BMSCs via mmu_circRNA_003795

Wen Ren, Lan Yang, Tian Deng, Caijuan Wu, Yuanjing Li, Jingwen Wu, Zhu Huang, Faliang Du, Lvhua Guo
Pages: 3732-3742
Published online on: 14 March 2019

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Article Open Access

β‑estradiol alleviates hypertension‑ and concanavalin A‑mediated inflammatory responses via modulation of connexins in peripheral blood lymphocytes

Xin Ni, Liang Zhang, Xin Ma, Li‑Ya Shan, Li Li, Jun‑Qiang Si, Xin‑Zhi Li, You‑Yi Zhang, Ke‑Tao Ma
Pages: 3743-3755
Published online on: 14 March 2019

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Article

Long noncoding RNA MALAT1 regulates sepsis in patients with burns by modulating miR‑214 with TLR5

Fengying Gao, Rong Chen, Yaofeng Xi, Qiujian Zhao, Haifeng Gao
Pages: 3756-3766
Published online on: 14 March 2019

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Article

Resveratrol is an arginase inhibitor contributing to vascular smooth muscle cell vasoconstriction via increasing cytosolic calcium

Chang Ik Choi, Bon Hyeock Koo, Dongeui Hong, Hyung Joo Kwon, Kwang Lae Hoe, Moo Ho Won, Young Myeong Kim, Hyun Kyo Lim, Sungwoo Ryoo
Pages: 3767-3774
Published online on: 14 March 2019

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Article

MicroRNA‑142‑3p inhibits trophoblast cell migration and invasion by disrupting the TGF‑β1/Smad3 signaling pathway

Enling Liu, Zheng Liu, Yuxiu Zhou, Mei Chen, Liqun Wang, Jun Li
Pages: 3775-3782
Published online on: 01 March 2019

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Article

Resveratrol improves cognition and decreases amyloid plaque formation in Tg6799 mice

Yue Chen, Guang‑Wei Shi, Zhi‑Man Liang, Shu‑Yue Sheng, Yu‑Sheng Shi, Li Peng, Ya‑Ping Wang, Fang Wang, Xing‑Mei Zhang
Pages: 3783-3790
Published online on: 06 March 2019

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Article

Protective effects of PNU‑282987 on sepsis‑induced acute lung injury in mice

Zhenzhen Shao, Quan Li, Shuang Wang, Zhixia Chen
Pages: 3791-3798
Published online on: 12 March 2019

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Article

EFLDO sensitizes liver cancer cells to TNFSF10‑induced apoptosis in a p53‑dependent manner

Yanbo Qu, Zhixin Liao, Xinzhu Wang, Jing Zhang, Chao Liu
Pages: 3799-3806
Published online on: 15 March 2019

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Article

miR‑124 regulates the osteogenic differentiation of bone marrow‑derived mesenchymal stem cells by targeting Sp7

Jia‑Zhen Tang, Xiao Lin, Jia‑Yu Zhong, Feng Xu, Feng Wu, Xiao‑Bo Liao, Rong‑Rong Cui, Fuxingzi Li, Ling‑Qing Yuan
Pages: 3807-3814
Published online on: 18 March 2019

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Article

Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ

Xiyan Zhang, Ning Li, Lingling Lu, Quan Lin, Liang Li, Ping Dong, Bo Yang, Dongliang Li, Jianchun Fei
Pages: 3815-3822
Published online on: 18 March 2019

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Article

MicroRNA‑132 mediates proliferation and migration of pulmonary smooth muscle cells via targeting PTEN

Zhen‑Hua Zeng, Wei‑Hua Wu, Qi Peng, Ya‑Hui Sun, Jian‑Xin Liu
Pages: 3823-3830
Published online on: 18 March 2019

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Article

Targeted next‑generation sequencing for research and diagnostics in congenital heart disease, and cleft lip and/or palate

Haisong Bu, Lin Liu, Shijun Hu, Zhiping Tan, Tianli Zhao
Pages: 3831-3840
Published online on: 15 March 2019

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Article

Aurora kinase inhibitor VX‑680 suppresses the proliferation and migration of HUVECs and angiogenesis

Xuejiao Sun, Shishi Niu, Zhen Zhang, Anyan Wang, Chengyuan Yang, Zichan Guo, Yuepeng Hao, Xiaozhong Li, Xiaoxia Wang
Pages: 3841-3847
Published online on: 27 February 2019

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Article

The role of ethanol in the pathogenesis of non‑bacterial prostatitis

Feng Liu, Lintao Liu, Zhong Wang, Lin Chen, Jianjun Yu, Xiaolin Xu
Pages: 3848-3854
Published online on: 27 February 2019

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Article

Genome‑wide profiling of lncRNA and mRNA expression in CRSwNP

Minglei Liu, Ping Guo, Jun An, Chao Guo, Fengxiang Lu, Yanhua Lei
Pages: 3855-3863
Published online on: 05 March 2019

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Article

Effect of docetaxel on the regulation of proliferation and apoptosis of human prostate cancer cells

Chongyi Yang, Weijie Zhang, Jie Wang, Pengpeng Chen, Jiangjiang Jin
Pages: 3864-3870
Published online on: 01 March 2019

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Article Open Access

Identification of hub genes in chronically hypoxic myocardium using bioinformatics analysis

Fan Wu, Feng Gao, Siyi He, Yingbin Xiao
Pages: 3871-3881
Published online on: 01 March 2019

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Article

MicroRNA‑122 downregulates Rho‑associated protein kinase 2 expression and inhibits the proliferation of prostate carcinoma cells

Hong Liu, Teng Hou, Wen Ju, Yifei Xing, Xiaoping Zhang, Jun Yang
Pages: 3882-3888
Published online on: 27 February 2019

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Article

Preparation of a monoclonal antibody against the carcinoembryonic antigen, glypican‑3

Yongdong Zhang, Dongri Qiu, Ronghua Li, Yawu Liu, Shuainan Shi, Yuliang Wang
Pages: 3889-3895
Published online on: 13 March 2019

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Article

MicroRNA‑663b downregulation inhibits proliferation and induces apoptosis in bladder cancer cells by targeting TUSC2

Jianying Chen, Bo Song, Guangqi Kong
Pages: 3896-3902
Published online on: 14 March 2019

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Article

Expression of steroidogenic enzymes in human placenta according to the gestational age

So‑Hye Hong, Seung Chul Kim, Mee‑Na Park, Jea Sic Jeong, Seung Yun Yang, Young Joo Lee, Ok‑Nam Bae, Hoe‑Saeng Yang, Sungbaek Seo, Kyu‑Sup Lee, Beum‑Soo An
Pages: 3903-3911
Published online on: 15 March 2019

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Article

Identification of red blood cell membrane defects in a patient with hereditary spherocytosis using next‑generation sequencing technology and matrix‑assisted laser desorption/ionization time‑of‑flight mass spectrometry

Leyla Türker Şener, Melih Aktan, Gürcan Albeniz, Aziz Şener, Duran Üstek, Işıl Albeniz
Pages: 3912-3922
Published online on: 14 March 2019

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Article

CircRNA‑0044073 is upregulated in atherosclerosis and increases the proliferation and invasion of cells by targeting miR‑107

Lin Shen, Yanyan Hu, Jianwei Lou, Sen Yin, Weiling Wang, Yuanyan Wang, Yong Xia, Wei Wu
Pages: 3923-3932
Published online on: 06 March 2019

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Article

MicroRNA‑629 inhibition suppresses the viability and invasion of non‑small cell lung cancer cells by directly targeting RUNX3 Retraction in /10.3892/mmr.2023.12930

Bufeng Zhuang, Youshuang Cheng
Pages: 3933-3940
Published online on: 27 February 2019

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Article

Butyrate inhibits the proliferation and induces the apoptosis of colorectal cancer HCT116 cells via the deactivation of mTOR/S6K1 signaling mediated partly by SIRT1 downregulation

Mingming Cao, Zhuoran Zhang, Su Han, Xi Lu
Pages: 3941-3947
Published online on: 01 March 2019

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MicroRNA‑708 inhibits the proliferation and invasion of osteosarcoma cells by directly targeting ZEB1 Retraction in /10.3892/mmr.2023.12936

Jun He, Deng Xiang, Yanshui Lin
Pages: 3948-3954
Published online on: 06 March 2019

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[Retracted] Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts

Yuehong Wu, Ouyang Li, Chengwen He, Yong Li, Min Li, Xiaoming Liu, Yujiong Wang, Yulong He
Pages: 3955-3955
Published online on: 13 March 2019

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[Erratum] Chemoresistance‑related long non‑coding RNA expression profiles in human breast cancer cells

Lei Huang, Lihua Zeng, Jiahui Chu, Pengfei Xu, Mingming Lv, Juan Xu, Juan Wen, Wenqu Li, Luyu Wang, Xiaowei Wu, Ziyi Fu, Hui Xie, Shui Wang
Pages: 3956-3956
Published online on: 01 March 2019

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Regulation of histone arginine methylation/demethylation by methylase and demethylase (Review)

Jing Zhang, Li Jing, Menghan Li, Lingfeng He, Zhigang Guo
Pages: 3963-3971
Published online on: 01 April 2019

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Differential urinary proteomics analysis of myocardial infarction using iTRAQ quantification

Lili Zou, Xubo Wang, Zhengguang Guo, Haidan Sun, Chen Shao, Yehong Yang, Wei Sun
Pages: 3972-3988
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Comparative analysis of gene expression profiles in children with type 1 diabetes mellitus

Liwei Qian, Honglei Shi, Meili Ding
Pages: 3989-4000
Published online on: 28 March 2019

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The function of miRNA‑153 against isoflurane‑induced neurotoxicity via Nrf2/ARE cytoprotection

Dong Shao, Zhouquan Wu, Shuying Bai, Guowei Fu, Zhiqing Zou
Pages: 4001-4010
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Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice

Rongrong Fu, Yanhua Jiang, Jing Zhou, Jinsong Zhang
Pages: 4011-4018
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Ginsenoside Rg5 induces apoptosis in human esophageal cancer cells through the phosphoinositide‑3 kinase/protein kinase B signaling pathway

Daoming Zhang, Aifu Wang, Jueping Feng, Qi Zhang, Linlin Liu, Hui Ren
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Upregulation of microRNA‑16 alters the response to inhaled β‑agonists in patients with asthma though modulating expression of ADRB2

Bo Yu, Lusu Yao, Cuiqiao Liu, Lina Tang, Tao Xing
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Inhibition of miR‑214 attenuates the migration and invasion of triple‑negative breast cancer cells

Yi Zhang, Zhijing Zhao, Siqi Li, Liying Dong, Yan Li, Ying Mao, Ying Liang, Yun Tao, Junfeng Ma
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Characterization of different biodegradable scaffolds in tissue engineering

Yan‑Ling Qiu, Xiao Chen, Ya‑Li Hou, Yan‑Juan Hou, Song‑Bo Tian, Yu‑He Chen, Li Yu, Min‑Hai Nie, Xu‑Qian Liu
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Targeting bacterial quorum sensing shows promise in improving intestinal barrier function following burn‑site infection

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Screening of important lncRNAs associated with the prognosis of lung adenocarcinoma, based on integrated bioinformatics analysis

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Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells Retraction in /10.3892/mmr.2025.13725

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
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Autophagy alleviates the decrease in proliferation of amyloid β1‑42‑treated bone marrow mesenchymal stem cells via the AKT/mTOR signaling pathway

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FOXM1 is a novel predictor of recurrence in patients with oral squamous cell carcinoma associated with an increase in epithelial‑mesenchymal transition

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Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure

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The anticancer effects of cinobufagin on hepatocellular carcinoma Huh‑7 cells are associated with activation of the p73 signaling pathway

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Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species

Ying Pi, Haifeng Liang, Qiang Yu, Yukun Yin, Haixia Xu, Yutian Lei, Zhongyu Han, Jing Tian
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miR‑329‑3p regulates neural stem cell proliferation by targeting E2F1

Dapeng Lin, Yao Shi, Yiwen Hu, Xiaowen Du, Guanjun Tu
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Mutational spectrum and associations with clinical features in patients with acute myeloid leukaemia based on next‑generation sequencing

Ying Li, Xiao Lv, Xueling Ge, Dai Yuan, Mei Ding, Changqing Zhen, Wenbo Zhao, Xin Liu, Xianghua Wang, Hongzhi Xu, Ying Li, Xin Wang
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Production of an aberrant splice variant of CCL5 is not caused by genetic mutation in the mammary glands of mastitis‑infected Holstein cows

Ling Yang, Ruiqing Guo, Zhihua Ju, Xiuge Wang, Qiang Jiang, Yong Liu, Han Zhao, Kaili He, Jianbin Li, Jinming Huang
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Revealing the interaction between intrauterine adhesion and vaginal microbiota using high‑throughput sequencing

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Identification and functional analysis of microRNAs in rats following focal cerebral ischemia injury

Xianchun Duan, Jianghua Gan, Dai‑Yin Peng, Qiuyu Bao, Ling Xiao, Liangbing Wei, Jian Wu
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Prenatal nicotine exposure induces depression‑like behavior in adolescent female rats via modulating neurosteroid in the hippocampus

Chong Zhang, Si‑Jing Fan, An‑Bang Sun, Zhen‑Zhen Liu, Lian Liu
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Umbilical cord blood‑derived Helios‑positive regulatory T cells promote angiogenesis in acute lymphoblastic leukemia in mice via CCL22 and the VEGFA‑VEGFR2 pathway

Xue Li, Dong Li, Qing Shi, Xiaoyang Huang, Xiuli Ju
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CBX3 predicts an unfavorable prognosis and promotes tumorigenesis in osteosarcoma

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MicroRNA‑25/ATXN3 interaction regulates human colon cancer cell growth and migration

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TGF‑β1 upregulates the expression of lncRNA‑ATB to promote atherosclerosis

Huapeng Yu, Shengting Ma, Ling Sun, Jing Gao, Chengjun Zhao
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Let‑7a‑5p may participate in the pathogenesis of diabetic nephropathy through targeting HMGA2

Tao Wang, Hua Zhu, Shufang Yang, Xiaoqiang Fei
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Circulating NK cell subsets and NKT‑like cells in renal transplant recipients with acute T‑cell‑mediated renal allograft rejection

Xiaoguang Xu, Yong Han, Haiyan Huang, Lili Bi, Xiangrui Kong, Xihui Ma, Bingyi Shi, Li Xiao
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Pharmacological inhibition of EZH2 combined with DNA‑damaging agents interferes with the DNA damage response in MM cells

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Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF‑7 breast cancer cells

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An lncRNA‑miRNA‑mRNA ceRNA network for adipocyte differentiation from human adipose‑derived stem cells

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miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN

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The role of lateral pterygoid muscle in the traumatic temporomandibular joint ankylosis: A gene chip based analysis

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Identification of potential diagnostic biomarkers for pneumonia caused by adenovirus infection in children by screening serum exosomal microRNAs

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High expression of B7‑H2 or B7‑H3 is associated with poor prognosis in hepatocellular carcinoma

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Exposure to polycyclic aromatic hydrocarbons derived from vehicle exhaust gas induces premature senescence in mouse lung fibroblast cells

Feng Yu, Ke Ye, Yunfeng Hu, Jincheng Li, Yonglei An, Dawei Qu
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Shikonin inhibits proliferation and induces apoptosis in glioma cells via downregulation of CD147

Na Guo, Rui Miao, Xingchun Gao, Dong Huang, Zhifang Hu, Naichun Ji, Ying Nan, Fengliang Jiang, Xingchun Gou
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Bioinformatics analysis of the prognostic value of CCT6A and associated signalling pathways in breast cancer

Kai Huang, Yi Zeng, Yunqing Xie, Liying Huang, Yu Wu
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Role of TLR‑4 in anti‑β2‑glycoprotein I‑induced activation of peritoneal macrophages and vascular endothelial cells in mice

Meiyun Wang, Xiangmin Kong, Yachao Xie, Chao He, Ting Wang, Hong Zhou
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A novel compound heterozygous mutation in SLC5A2 contributes to familial renal glucosuria in a Chinese family, and a review of the relevant literature

Shentang Li, Yeyi Yang, Lihua Huang, Min Kong, Zuocheng Yang
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Identification of suitable reference genes for gene expression studies in rat skeletal muscle following sciatic nerve crush injury

Xinghui Wang, Hualong Zhao, Jun Ni, Jiacheng Pan, Hao Hua, Yaxian Wang
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miR‑146a‑5p expression is upregulated by the CXCR4 antagonist TN14003 and attenuates SDF‑1‑induced cartilage degradation

Di Jia, Yanlin Li, Rui Han, Kun Wang, Guofeng Cai, Chuan He, Lingjian Yang
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Preliminary investigation of the effects of an FCF inhibitor interference with Septin in the early stage embryos in mice

Shao‑Qin Ge, Yin‑Ling Wu, Jin‑Liang Zhu, Yuan Tian, Shu‑Song Wang, Zhang‑Quan Gao
Pages: 4401-4406
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MicroRNA‑9 suppresses human prostate cancer cell viability, invasion and migration via modulation of mitogen‑activated protein kinase kinase kinase 3 expression

Zunmeng Sang, Xuewen Jiang, Longfei Guo, Gang Yin
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A novel NHS mutation in a Chinese family with Nance‑Horan Syndrome

Meirong Wei, Anhui Qi, Haiming Mo, Kailin Wu, Xu Ma, Binbin Wang
Pages: 4419-4424
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lncRNA AWPPH promotes proliferation and inhibits apoptosis of non‑small cell lung cancer cells by activating the Wnt/β‑catenin signaling pathway

Zhan Song, Junfeng Du, Lirong Zhou, Baohua Sun
Pages: 4425-4432
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MicroRNA‑302a upregulation mediates chemo‑resistance in prostate cancer cells

Yuqi Wu, Li Hu, Zizhen Qin, Xiangwei Wang
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Serum‑derived hepatitis C virus can infect human glioblastoma cell line SF268 and activate the PI3K‑Akt pathway

Guosheng Yuan, Liang Rong, Junwei Liu, Zhenzhen Zhang, Chengguang Hu, Mingxiao Chen, Ling Ma, Yong‑Yuan Zhang, Yi‑Ping Li, Yuanping Zhou
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Sanguinarine induces apoptosis of human lens epithelial cells by increasing reactive oxygen species via the MAPK signaling pathway

Yue Zhang, Wan‑Rong Huang
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MicroRNA‑494 inhibits apoptosis of murine vascular smooth muscle cells in vitro

Rongrong Cui, Senlin Ye, Jiayu Zhong, Lingjuan Liu, Shijun Li, Xiao Lin, Lingqing Yuan, Lu Yi
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Long noncoding RNA NEAT1 sponges miR‑125a‑5p to suppress cardiomyocyte apoptosis via BCL2L12

Hong Yan, Huasheng Liang, Lie Liu, Dongli Chen, Qianhuan Zhang
Pages: 4468-4474
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Downregulation of microRNA‑183‑5p inhibits the proliferation and invasion of colorectal cancer cells by inactivating the reticulocalbin‑2/Wnt/β‑catenin signaling pathway Expression of Concern in /10.3892/mmr.2025.13659

Gang Wang, Jingrong Zhou, Feng Lu, Lei Qiu, Liang Xu, Xiuwei Yang, Yongchang Miao
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A Chinese pedigree with a novel mutation in GJB1 gene and a rare variation in DHTKD1 gene for diverse Charcot‑Marie‑Tooth diseases

Zhen‑Hua Zhao, Zhi‑Ting Chen, Rui‑Ling Zhou, Yin‑Zhou Wang
Pages: 4484-4490
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Renal dysfunction in a mouse model of GDM is prevented by metformin through MAPKs

Zhengfei Liu, Xinyang Yu, Chao Tong, Hongbo Qi
Pages: 4491-4499
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Circular RNA expression alterations in colon tissues of Crohn's disease patients

Yu Qi Qiao, Chen Wen Cai, Jun Shen, Qing Zheng, Zhi Hua Ran
Pages: 4500-4506
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Protective effects of propofol on experimental neonatal acute lung injury

Xiongwu Yu, Chuanfeng Li
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HPT axis‑independent TSHβ splice variant regulates the synthesis of thyroid hormone in mice

Chunrong Liu, Jun Miao, Xiaorong Liu, Zhankao Zhao, Tianlei Kou, Jing Liu, Ruimin Wang, Lanying Li, Qian Dong
Pages: 4514-4522
Published online on: 22 March 2019

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August-2026 Volume 34 Issue 2

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

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Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

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Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
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Hua Luo
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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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CiteScore: 7.3

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Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

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[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
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PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

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From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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