|
1
|
Niu G, Wright KL, Huang M, Song L, Haura
E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, et al:
Constitutive Stat3 activity up-regulates VEGF expression and tumor
angiogenesis. Oncogene. 21:2000–2008. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Gray GK, McFarland BC, Nozell SE and
Benveniste EN: NF-κB and STAT3 in glioblastoma: Therapeutic targets
coming of age. Expert Rev Neurother. 14:1293–1306. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Stupp R, Mason WP, van den Bent MJ, Weller
M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn
U, et al: Radiotherapy plus concomitant and adjuvant temozolomide
for glioblastoma. N Engl J Med. 352:987–996. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Roa W, Brasher PM, Bauman G, Anthes M,
Bruera E, Chan A, Fisher B, Fulton D, Gulavita S, Hao C, et al:
Abbreviated course of radiation therapy in older patients with
glioblastoma multiforme: A prospective randomized clinical trial. J
Clin Oncol. 22:1583–1588. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hide T, Takezaki T, Nakamura H, Kuratsu J
and Kondo T: Brain tumor stem cells as research and treatment
targets. Brain Tumor Pathol. 25:67–72. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Yang F, Brown C, Buettner R, Hedvat M,
Starr R, Scuto A, Schroeder A, Jensen M and Jove R: Sorafenib
induces growth arrest and apoptosis of human glioblastoma cells
through the dephosphorylation of signal transducers and activators
of transcription 3. Mol Cancer Ther. 9:953–962. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Liu Y, Li C and Lin J: STAT3 as a
therapeutic target for glioblastoma. Anticancer Agents Med Chem.
10:512–519. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Koskela HL, Eldfors S, Ellonen P, van
Adrichem AJ, Kuusanmäki H, Andersson EI, Lagström S, Clemente MJ,
Olson T, Jalkanen SE, et al: Somatic STAT3 mutations in large
granular lymphocytic leukemia. N Engl J Med. 366:1905–1913. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhang XP, Zheng G, Zou L, Liu HL, Hou LH,
Zhou P, Yin DD, Zheng QJ, Liang L, Zhang SZ, et al: Notch
activation promotes cell proliferation and the formation of neural
stem cell-like colonies in human glioma cells. Mol Cell Biochem.
307:101–108. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Fan QW, Cheng C, Knight ZA, Haas-Kogan D,
Stokoe D, James CD, McCormick F, Shokat KM and Weiss WA: EGFR
signals to mTOR through PKC and independently of Akt in glioma. Sci
Signal. 2:ra42009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Molina JR, Foster NR, Reungwetwattana T,
Nelson GD, Grainger AV, Steen PD, Stella PJ, Marks R, Wright J and
Adjei AA: A phase II trial of the Src-kinase inhibitor saracatinib
after four cycles of chemotherapy for patients with extensive stage
small cell lung cancer: NCCTG trial N-0621. Lung Cancer.
85:245–250. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lin M, Yao Z, Zhao N and Zhang C: TLK2
enhances aggressive phenotypes of glioblastoma cells through the
activation of SRC signaling pathway. Cancer Biol Ther. 20:101–108.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Nygaard HB, Wagner AF, Bowen GS, Good SP,
MacAvoy MG, Strittmatter KA, Kaufman AC, Rosenberg BJ, Sekine-Konno
T, Varma P, et al: A phase Ib multiple ascending dose study of the
safety, tolerability, and central nervous system availability of
AZD0530 (saracatinib) in Alzheimer's disease. Alzheimers Res Ther.
7:352015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
De Luca A, D'Alessio A, Gallo M, Maiello
MR, Bode AM and Normanno N: Src and CXCR4 are involved in the
invasiveness of breast cancer cells with acquired resistance to
lapatinib. Cell Cycle. 13:148–156. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liu J, Xu X, Feng X, Zhang B and Wang J:
Adenovirus-mediated delivery of bFGF small interfering RNA reduces
STAT3 phosphorylation and induces the depolarization of
mitochondria and apoptosis in glioma cells U251. J Exp Clin Cancer
Res. 30:802011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Baumann BC, Dorsey JF, Benci JL, Joh DY
and Kao GD: Stereotactic intracranial implantation and in vivo
bioluminescent imaging of tumor xenografts in a mouse model system
of glioblastoma multiforme. J Vis Exp:. (pii): 40892012.PubMed/NCBI
|
|
17
|
Sansone P and Bromberg J: Targeting the
interleukin-6/Jak/stat pathway in human malignancies. J Clin Oncol.
30:1005–1014. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wadghiri YZ, Li J, Wang J, Hoang DM, Sun
Y, Xu H, Tsui W, Li Y, Boutajangout A, Wang A, et al: Detection of
amyloid plaques targeted by bifunctional USPIO in Alzheimer's
disease transgenic mice using magnetic resonance microimaging. PLoS
One. 8:e570972013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tomayko MM and Reynolds CP: Determination
of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother
Pharmacol. 24:148–154. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Alvarez JV and Frank DA: Genome-wide
analysis of STAT target genes: Elucidating the mechanism of
STAT-mediated oncogenesis. Cancer Biol Ther. 3:1045–1050. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Leslie K, Gao SP, Berishaj M, Podsypanina
K, Ho H, Ivashkiv L and Bromberg J: Differential
interleukin-6/Stat3 signaling as a function of cellular context
mediates Ras-induced transformation. Breast Cancer Res. 12:R802010.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Sanseverino I, Purificato C, Gauzzi MC and
Gessani S: Revisiting the specificity of small molecule inhibitors:
The example of stattic in dendritic cells. Chem Biol. 19:1213–1216.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Barre B, Vigneron A and Coqueret O: The
STAT3 transcription factor is a target for the Myc and riboblastoma
proteins on the Cdc25A promoter. J Biol Chem. 280:15673–15681.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Rao DD, Vorhies JS, Senzer N and
Nemunaitis J: siRNA vs. shRNA: Similarities and differences. Adv
Drug Deliv Rev. 61:746–759. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Gao LF, Xu DQ, Wen LJ, Zhang XY, Shao YT
and Zhao XJ: Inhibition of STAT3 expression by siRNA suppresses
growth and induces apoptosis in laryngeal cancer cells. Acta
Pharmacol Sin. 26:377–383. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Firer MA and Gellerman G: Targeted drug
delivery for cancer therapy: The other side of antibodies. J
Hematol Oncol. 5:702012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Formisano L, Nappi L, Rosa R, Marciano R,
D'Amato C, D'Amato V, Damiano V, Raimondo L, Iommelli F, Scorziello
A, et al: Epidermal growth factor-receptor activation modulates
Src-dependent resistance to lapatinib in breast cancer models.
Breast Cancer Res. 16:R452014. View
Article : Google Scholar : PubMed/NCBI
|
|
28
|
de Wispelaere M, LaCroix AJ and Yang PL:
The small molecules AZD0530 and dasatinib inhibit dengue virus RNA
replication via Fyn kinase. J Virol. 87:7367–7381. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Bourke LT, Knight RA, Latchman DS,
Stephanou A and McCormick J: Signal transducer and activator of
transcription-1 localizes to the mitochondria and modulates
mitophagy. JAKSTAT. 2:e256662013.PubMed/NCBI
|
|
30
|
Chan SL and Yu VC: Proteins of the bcl-2
family in apoptosis signalling: From mechanistic insights to
therapeutic opportunities. Clin Exp Pharmacol Physiol. 31:119–128.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Gielen PR, Aftab Q, Ma N, Chen VC, Hong X,
Lozinsky S, Naus CC and Sin WC: Connexin43 confers Temozolomide
resistance in human glioma cells by modulating the mitochondrial
apoptosis pathway. Neuropharmacology. 75:539–548. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Coleman CB, McGraw JE, Feldman ER, Roth
AN, Keyes LR, Grau KR, Cochran SL, Waldschmidt TJ, Liang C, Forrest
JC and Tibbetts SA: A gammaherpesvirus Bcl-2 ortholog blocks B cell
receptor-mediated apoptosis and promotes the survival of developing
B cells in vivo. PLoS Pathog. 10:e10039162014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Abdalla F, Nookala A, Padhye SB, Kumar A
and Bhat HK: 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol} (TIMBD)
suppresses HIV1-gp120 mediated production of IL6 and IL8 but not
CCL5. Sci Rep. 7:81292017. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Guo Y, Zang Y, Lv L, Cai F, Qian T, Zhang
G and Feng Q: [Corrigendum] IL-8 promotes proliferation and
inhibition of apoptosis via STAT3/AKT/NF-κB pathway in prostate
cancer. Mol Med Rep. 19:29702019.PubMed/NCBI
|
