|
1
|
Li Y, Shi X, Li J, Zhang M and Yu B:
Knockdown of KLF11 attenuates hypoxia/reoxygenation injury via
JAK2/STAT3 signaling in H9c2. Apoptosis. 22:510–518. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Zhang Y, Chen G, Zhong S, Zheng F, Gao F,
Chen Y, Huang Z, Cai W, Li W, Liu X, et al: N-n-butyl haloperidol
iodide ameliorates cardiomyocytes hypoxia/reoxygenation injury by
extracellular calcium-dependent and -independent mechanisms. Oxid
Med Cell Longev. 2013:9123102013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ouyang F, Huang H, Zhang M, Chen M, Huang
H, Huang F and Zhou S: HMGB1 induces apoptosis and EMT in
association with increased autophagy following H/R injury in
cardiomyocytes. Int J Mol Med. 37:679–689. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Liu S, Man Y and Zhao L: Sinomenine
inhibits lipopolysaccharide-induced inflammatory injury by
regulation of miR-101/MKP-1/JNK pathway in keratinocyte cells.
Biomed Pharmacother. 101:422–429. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Liu J, Hua R, Gong Z, Shang B, Huang Y,
Guo L, Liu T and Xue J: Human amniotic epithelial cells inhibit
CD4+ T cell activation in acute kidney injury patients
by influencing the miR-101-c-Rel-IL-2 pathway. Mol Immunol.
81:76–84. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lin C, Huang F, Li QZ and Zhang YJ:
miR-101 suppresses tumor proliferation and migration, and induces
apoptosis by targeting EZH2 in esophageal cancer cells. Int J Clin
Exp Pathol. 7:6543–6550. 2014.PubMed/NCBI
|
|
7
|
Li D, Zhan S, Wang Y, Wang L, Zhong T, Li
L, Fan J, Xiong C, Wang Y and Zhang H: Role of microRNA-101a in the
regulation of goat skeletal muscle satellite cell proliferation and
differentiation. Gene. 572:198–204. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Cao K, Li J, Zhao Y, Wang Q, Zeng Q, He S,
Yu L, Zhou J and Cao P: miR-101 inhibiting cell proliferation,
migration and invasion in hepatocellular carcinoma through
downregulating Girdin. Mol Cells. 39:96–102. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kwon JY, Park BS, Kim YH, Kim YD, Kim CH,
Yoon JY and Yoon JU: Remifentanil protects human keratinocytes
against hypoxia-reoxygenation injury through activation of
autophagy. PLoS One. 10:e01169822015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Liu LS, Bai XQ, Gao Y, Wu Q, Ren Z, Li Q,
Pan LH, He NY, Peng J and Tang ZH: PCSK9 promotes oxLDL-induced
PC12 cell apoptosis through the Bcl-2/Bax-Caspase 9/3 signaling
pathway. J Alzheimers Dis. 57:723–734. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Yating Q, Yuan Y, Wei Z, Qing G, Xingwei
W, Qiu Q and Lili Y: Oxidized LDL induces apoptosis of human
retinal pigment epithelium through activation of ERK-Bax/Bcl-2
signaling pathways. Curr Eye Res. 40:415–422. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Raisova M, Hossini AM, Eberle J, Riebeling
C, Wieder T, Sturm I, Daniel PT, Orfanos CE and Geilen CC: The
Bax/Bcl-2 ratio determines the susceptibility of human melanoma
cells to CD95/Fas-mediated apoptosis. J Invest Dermatol.
117:333–340. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kanda T and Takahashi T: Interleukin-6 and
cardiovascular diseases. Jpn Heart J. 45:183–193. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Adefolaju GA, Theron KE and Hosie MJ:
Effects of HIV protease, nucleoside/non-nucleoside reverse
transcriptase inhibitors on Bax, Bcl-2 and apoptosis in two
cervical cell lines. Biomed Pharmacother. 68:241–251. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liang S, Sun K, Wang Y, Dong S, Wang C,
Liu L and Wu Y: Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS
death receptor pathway in apoptosis induced by zinc oxide
nanoparticles in human aortic endothelial cells and the protective
effect by alpha-lipoic acid. Chem Biol Interact. 258:40–51. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Zahs A, Bird MD, Ramirez L, Choudhry MA
and Kovacs EJ: Anti-IL-6 antibody treatment but not IL-6 knockout
improves intestinal barrier function and reduces inflammation after
binge ethanol exposure and burn injury. Shock. 39:373–379. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Esposito E and Cuzzocrea S: TNF-alpha as a
therapeutic target in inflammatory diseases, ischemia-reperfusion
injury and trauma. Curr Med Chem. 16:3152–3167. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ji K, Zhang M, Chu Q, Gan Y, Ren H, Zhang
L, Wang L, Li X and Wang W: The role of p-STAT3 as a prognostic and
clinicopathological marker in colorectal cancer: A systematic
review and meta-analysis. PLoS One. 11:e01601252016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Liu R, Xu N, Yi W, Huang K and Su M:
Electroacupuncture effect on neurological behavior and tyrosine
kinase-JAK 2 in rats with focal cerebral ischemia. J Tradit Chin
Med. 32:465–470. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Lv X, Zhang Y, Cui Y, Ren Y, Li R and Rong
Q: Inhibition of microRNA155 relieves sepsisinduced liver injury
through inactivating the JAK/STAT pathway. Mol Med Rep.
12:6013–6018. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Song Z, Zhao X, Gao Y, Liu M, Hou M, Jin H
and Cui Y: Recombinant human brain natriuretic peptide ameliorates
trauma-induced acute lung injury via inhibiting JAK/STAT signaling
pathway in rats. J Trauma Acute Care Surg. 78:980–987. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Fowler ED, Benoist D, Drinkhill MJ, Stones
R, Helmes M, Wust RC, Stienen GJ, Steele DS and White E: Decreased
creatine kinase is linked to diastolic dysfunction in rats with
right heart failure induced by pulmonary artery hypertension. J Mol
Cell Cardiol. 86:1–8. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li Y, Wang K, Jiang Y and Chen J:
Protective effect of heart-fatty acid binding protein on
lipopolysaccharide-induced cardiomyocyte damage. Zhong Nan Da Xue
Xue Bao Yi Xue Ban. 40:457–463. 2015.(In Chinese). PubMed/NCBI
|
|
25
|
Chai HT, Yip HK, Sun CK, Hsu SY and Leu S:
AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances
blood flow recovery in rats with critical limb ischemia. J Inflamm
(Lond). 13:182016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Yu X and Li Z, Wan Q, Cheng X, Zhang J,
Pathak JL and Li Z: Inhibition of JAK2/STAT3 signaling suppresses
bone marrow stromal cells proliferation and osteogenic
differentiation, and impairs bone defect healing. Biol Chem.
399:1313–1323. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Tang J, Wang G, Liu Y, Fu Y, Chi J, Zhu Y,
Zhao Y and Yin X: Cyclosporin A induces cardiomyocyte injury
through calcium-sensing receptor-mediated calcium overload.
Pharmazie. 66:52–57. 2011.PubMed/NCBI
|
|
28
|
Yan H, Zhang Y, Lv SJ, Wang L, Liang GP,
Wan QX and Peng X: Effects of glutamine treatment on myocardial
damage and cardiac function in rats after severe burn injury. Int J
Clin Exp Pathol. 5:651–659. 2012.PubMed/NCBI
|
|
29
|
Hassan M, Watari H, AbuAlmaaty A, Ohba Y
and Sakuragi N: Apoptosis and molecular targeting therapy in
cancer. Biomed Res Int. 2014:1508452014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mohseni M, Mihandoost E, Shirazi A,
Sepehrizadeh Z, Bazzaz JT and Ghazi-khansari M: Melatonin may play
a role in modulation of bax and bcl-2 expression levels to protect
rat peripheral blood lymphocytes from gamma irradiation-induced
apoptosis. Mutat Res. 738-739:19–27. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Pan LL, Wang AY, Huang YQ, Luo Y and Ling
M: Mangiferin induces apoptosis by regulating Bcl-2 and Bax
expression in the CNE2 nasopharyngeal carcinoma cell line. Asian
Pac J Cancer Prev. 15:7065–7068. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Pepper C, Hoy T and Bentley DP: Bcl-2/Bax
ratios in chronic lymphocytic leukaemia and their correlation with
in vitro apoptosis and clinical resistance. Br J Cancer.
76:935–938. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chen D, Zheng X, Kang D, Yan B, Liu X, Gao
Y and Zhang K: Apoptosis and expression of the Bcl-2 family of
proteins and P53 in human pancreatic ductal adenocarcinoma. Med
Princ Pract. 21:68–73. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Tanaka T, Narazaki M and Kishimoto T: IL-6
in inflammation, immunity, and disease. Cold Spring Harb Perspect
Biol. 6:a0162952014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Rose-John S: IL-6 trans-signaling via the
soluble IL-6 receptor: Importance for the pro-inflammatory
activities of IL-6. Int J Biol Sci. 8:1237–1247. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Van Wagoner NJ and Benveniste EN:
Interleukin-6 expression and regulation in astrocytes. J
Neuroimmunol. 100:124–139. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Lu W, Kang J, Hu K, Tang S, Zhou X, Yu S
and Xu L: Angiotensin-(1–7) relieved renal injury induced by
chronic intermittent hypoxia in rats by reducing inflammation,
oxidative stress and fibrosis. Braz J Med Biol Res. 50:e55942017.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhao G, Yu YM, Kaneki M, Bonab AA,
Tompkins RG and Fischman AJ: Simvastatin reduces burn
injury-induced splenic apoptosis via downregulation of the
TNF-alpha/NF-kappaB pathway. Ann Surg. 261:1006–1012. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Cheong CU, Chang CP, Chao CM, Cheng BC,
Yang CZ and Chio CC: Etanercept attenuates traumatic brain injury
in rats by reducing brain TNF-α contents and by stimulating newly
formed neurogenesis. Mediators Inflamm. 2013:6208372013. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Roshan S, Liu YY, Banafa A, Chen HJ, Li
KX, Yang GX, He GY and Chen MJ: Fucoidan induces apoptosis of HepG2
cells by down-regulating p-Stat3. J Huazhong Univ Sci Technolog Med
Sci. 34:330–336. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Liu Z, Gan L, Zhou Z, Jin W and Sun C:
SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3
signaling pathway in 3T3-L1 adipocyte. Immunobiology. 220:947–953.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Trung LQ, Espinoza JL, An DT, Viet NH,
Shimoda K and Nakao S: Resveratrol selectively induces apoptosis in
malignant cells with the JAK2V617F mutation by inhibiting the JAK2
pathway. Mol Nutr Food Res. 59:2143–2154. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chen C, Jia KY, Zhang HL and Fu J: MiR-195
enhances cardiomyocyte apoptosis induced by hypoxia/reoxygenation
injury via downregulating c-myb. Eur Rev Med Pharmacol Sci.
20:3410–3416. 2016.PubMed/NCBI
|
|
44
|
Quintás-Cardama A and Verstovsek S:
Molecular pathways: Jak/STAT pathway: Mutations, inhibitors, and
resistance. Clin Cancer Res. 19:1933–1940. 2013. View Article : Google Scholar : PubMed/NCBI
|
