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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2020 Volume 21 Issue 1

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Molecular basis of degenerative spinal disorders from a proteomic perspective (Review)

Chang Liu, Minghui Yang, Libangxi Liu, Yang Zhang, Qi Zhu, Cong Huang, Hongwei Wang, Yaqing Zhang, Haiyin Li, Changqing Li, Bo Huang, Chencheng Feng, Yue Zhou
Pages: 9-19
Published online on: 12 November 2019

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Article Open Access

Aspirin metabolites 2,3‑DHBA and 2,5‑DHBA inhibit cancer cell growth: Implications in colorectal cancer prevention

Ranjini Sankaranarayanan, Chaitanya K. Valiveti, Rakesh Dachineni, D. Ramesh Kumar, Tana Lick, G. Jayarama Bhat
Pages: 20-34
Published online on: 18 November 2019

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Article Open Access

MicroRNA‑542‑3p represses OTUB1 expression to inhibit migration and invasion of esophageal cancer cells

Jun Sun, Yong Deng, Jin Shi, Wengang Yang
Pages: 35-42
Published online on: 20 November 2019

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Article Open Access

miR‑204 inhibits the osteogenic differentiation of mesenchymal stem cells by targeting bone morphogenetic protein 2

Xiaofeng Jiang, Zuofu Zhang, Tao Peng, Guangda Wang, Qiang Xu, Guangrun Li
Pages: 43-50
Published online on: 05 November 2019

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Article Open Access

Exploratory study on application of MALDI‑TOF‑MS to detect serum and urine peptides related to small cell lung carcinoma

Panpan Lv, Zeyuan Liu, Bin Xu, Chuanhao Tang, Xiaoyan Li, Haifeng Qin, Shaoxing Yang, Hongjun Gao, Kun He, Xiaoqing Liu
Pages: 51-60
Published online on: 05 November 2019

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Article Open Access

KR‑12‑a6 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via BMP/SMAD signaling

Lanqing Fu, Peicheng Jin, Yajun Hu, Hougen Lu, Linlin Su
Pages: 61-68
Published online on: 22 November 2019

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Article Open Access

Silencing of RBP‑JK promotes the differentiation of bone marrow mesenchymal stem cells into vascular endothelial cells

Zhengliang Luo, Yong Dai, Min Chen, Chen Zhu, Kerong Wu, Guoyuan Li, Xifu Shang
Pages: 69-76
Published online on: 06 November 2019

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Article Open Access

Anti‑Nogo‑A antibody promotes brain function recovery after cardiopulmonary resuscitation in rats by reducing apoptosis

Qinqin Wu, Haihong Zhang, Hu Nie, Zhi Zeng
Pages: 77-88
Published online on: 20 November 2019

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Article Open Access

The inhibition of miR‑101a‑3p alleviates H/R injury in H9C2 cells by regulating the JAK2/STAT3 pathway

Jingying Liu, Juanjuan Wang, Yuzhen Ning, Fengying Chen
Pages: 89-96
Published online on: 05 November 2019

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Article Open Access

Disorders of sex development: Genetic characterization of a patient cohort

Mary García-Acero, Olga Moreno-Niño, Fernando Suárez-Obando, Mónica Molina, María Carolina Manotas, Juan Carlos Prieto, Catalina Forero, Camila Céspedes, Jaime Pérez, Nicolas Fernandez, Adriana Rojas
Pages: 97-106
Published online on: 12 November 2019

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Article Open Access

Altered Nurr1 protein expression in the hippocampal CA1 region following transient global cerebral ischemia

Joon Ha Park, Ji Hyeon Ahn, Dae Won Kim, Tae‑Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae‑Chul Lee, Hyang‑Ah Lee, Go Eun Yang, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 107-114
Published online on: 20 November 2019

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Article Open Access

Neuroprotective effect of CPCGI on Alzheimer's disease and its mechanism

Xiaopeng Wang, Jing Zhao
Pages: 115-122
Published online on: 20 November 2019

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Article Open Access

Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats Retraction in /10.3892/mmr.2025.13656

Cun‑Xian Shi, Jin Jin, Xue‑Qin Wang, Teng Song, Guang‑Hong Li, Ke‑Zhong Li, Jia‑Hai Ma
Pages: 123-130
Published online on: 20 November 2019

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Article Open Access

Iridoid glycosides from Radix Scrophulariae attenuates focal cerebral ischemia‑reperfusion injury via inhibiting endoplasmic reticulum stress‑mediated neuronal apoptosis in rats

Yanyue Chen, Lei Zhang, Xueyuan Gong, Hengpei Gong, Rubin Cheng, Fengmei Qiu, Xiaoming Zhong, Zhen Huang
Pages: 131-140
Published online on: 20 November 2019

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Article Open Access

Construction and analysis of circular RNA molecular regulatory networks in clear cell renal cell carcinoma

Chuanyu Ma, Jie Qin, Junpeng Zhang, Xingli Wang, Dongjun Wu, Xiunan Li
Pages: 141-150
Published online on: 11 November 2019

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Article Open Access

Interleukin‑37 is increased in peripheral blood mononuclear cells of coronary heart disease patients and inhibits the inflammatory reaction

Huimin Li, Chen Shen, Bingni Chen, Jing Du, Bin Peng, Wei Wang, Fanwu Chi, Xiaoqiang Dong, Zhong Huang, Chao Yang
Pages: 151-160
Published online on: 06 November 2019

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Article Open Access

Roxatidine inhibits fibrosis by inhibiting NF‑κB and MAPK signaling in macrophages sensing breast implant surface materials

Litong Ji, Tie Wang, Lining Tian, Hongjiang Song, Meizhuo Gao
Pages: 161-172
Published online on: 12 November 2019

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Article Open Access

Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells

Sheng Zhou, Jing Yang, Mingwei Wang, Danying Zheng, Yizhi Liu
Pages: 173-180
Published online on: 12 November 2019

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Article Open Access

Antifibrotic effects of specific siRNA targeting connective tissue growth factor delivered by polyethyleneimine‑functionalized magnetic iron oxide nanoparticles on LX‑2 cells

Qin Yu, Xiaoqin Xiong, Lei Zhao, Tingting Xu, Qianhua Wang
Pages: 181-190
Published online on: 20 November 2019

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Article Open Access

The COL6A1 rs201153092 single nucleotide polymorphism, associates with thoracic ossification of the posterior longitudinal ligament

Peng Wang, Ze Teng, Xiaoguang Liu, Xiao Liu, Chao Kong, Shibao Lu
Pages: 191-200
Published online on: 22 November 2019

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Article Open Access

Mitochondrial tRNAAla 5601C>T variant may affect the clinical expression of the LHON‑related ND4 11778G>A mutation in a family

Yu Ding, Yu‑Feng Ye, Mei‑Ya Li, Bo‑Hou Xia, Jian‑Hang Leng
Pages: 201-208
Published online on: 22 November 2019

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Article Open Access

miR‑218 functions as a tumor suppressor gene in cervical cancer Retraction in /10.3892/mmr.2024.13326

Zhen Liu, Lin Mao, Linlin Wang, Hong Zhang, Xiaoxia Hu
Pages: 209-219
Published online on: 11 November 2019

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Article Open Access

Rhizoma Paridis total saponins alleviate H2O2‑induced oxidative stress injury by upregulating the Nrf2 pathway

Baocheng Zhao, Zhenjun Wang, Jiagang Han, Guanghui Wei, Bingqiang Yi, Zhulin Li
Pages: 220-228
Published online on: 20 November 2019

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Article Open Access

Extraction and isolation of the active ingredients of dandelion and its antifungal activity against Candida albicans

Yinku Liang, Hongbo Duan, Ping Zhang, Hao Han, Feixiong Gao, Yunxiang Li, Zhongyang Xu
Pages: 229-239
Published online on: 06 November 2019

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Article Open Access

A novel GPR143 mutation in a Chinese family with X‑linked ocular albinism type 1

Xuhui Gao, Tiecheng Liu, Xuan Cheng, Aiai Dai, Wei Liu, Runpu Li, Maonian Zhang
Pages: 240-248
Published online on: 12 November 2019

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Article Open Access

Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells

Yifan Wu, Yiyang Zhao, Xuanhong He, Zhiqiang He, Tian Wang, Linxi Wan, Lai Chen, Nianlong Yan
Pages: 249-257
Published online on: 06 November 2019

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Article Open Access

Berberine ameliorates lipopolysaccharide‑induced inflammatory responses in mouse inner medullary collecting duct‑3 cells by downregulation of NF‑κB pathway

Dong‑Gu Kim, Ji‑Won Choi, Il‑Joo Jo, Myoung‑Jin Kim, Ho‑Sub Lee, Seung‑Heon Hong, Ho‑Joon Song, Gi‑Sang Bae, Sung‑Joo Park
Pages: 258-266
Published online on: 19 November 2019

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Article Open Access

Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer Retraction in /10.3892/mmr.2026.13886

Wei Wei, Cun Liu
Pages: 267-281
Published online on: 20 November 2019

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Article Open Access

Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats

Yang Jiao, Yang Yu, Bo Li, Xiyan Gu, Keliang Xie, Guolin Wang, Yonghao Yu
Pages: 282-290
Published online on: 05 November 2019

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Article Open Access

LncRNA MALAT1 promotes neuropathic pain progression through the miR‑154‑5p/AQP9 axis in CCI rat models

Jianping Wu, Chuanguang Wang, Haiyang Ding
Pages: 291-303
Published online on: 20 November 2019

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Article Open Access

Dioscin attenuates oxLDL uptake and the inflammatory reaction of dendritic cells under high glucose conditions by blocking p38 MAPK

Ying Li, Yong Li, Te Yang, Ming Wang
Pages: 304-310
Published online on: 06 November 2019

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Screening and identification of key biomarkers in prostate cancer using bioinformatics

Song Li, Junqing Hou, Weibo Xu
Pages: 311-319
Published online on: 06 November 2019

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Article Open Access

Cortex Mori Radicis extract promotes neurite outgrowth in diabetic rats by activating PI3K/AKT signaling and inhibiting Ca2+ influx associated with the upregulation of transient receptor potential canonical channel 1 Corrigendum in /10.3892/mmr.2020.11008

Min Lu, Tao Yi, Yong Xiong, Qian Wang, Nina Yin
Pages: 320-328
Published online on: 21 November 2019

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Article Open Access

CARD10 promotes the progression of renal cell carcinoma by regulating the NF‑κB signaling pathway

Longfei Peng, Ke He, Zhangjun Cao, Liangkuan Bi, Dexin Yu, Qi Wang, Jinyou Wang
Pages: 329-337
Published online on: 21 November 2019

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Article Open Access

Increased mitochondrial DNA copy number protects hair cells and HEI‑OC1 cells against drug‑induced apoptosis

Honglin Mei, Dongmei Mei, Huiqian Yu, Shan Sun, Yan Chen, Yanping Zhang, Renjie Chai, Huawei Li
Pages: 338-346
Published online on: 20 November 2019

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Article Open Access

A 21‑gene Support Vector Machine classifier and a 10‑gene risk score system constructed for patients with gastric cancer

Hui Jiang, Jiming Gu, Jun Du, Xiaowei Qi, Chengjia Qian, Bojian Fei
Pages: 347-359
Published online on: 21 November 2019

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Article Open Access

Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma

Jie Wei, Zhijie Xu, Xi Chen, Xiang Wang, Shuangshuang Zeng, Long Qian, Xue Yang, Chunlin Ou, Wei Lin, Zhicheng Gong, Yuanliang Yan
Pages: 360-370
Published online on: 20 November 2019

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Article

IL‑37 expression is decreased in patients with hyperhomocysteinemia and protects cells from inflammatory injury by homocysteine

Sen Wang, Zhen Huang, Wenrui Li, Suhui He, Hongmei Wu, Jiandong Zhu, Rumeng Li, Zhuangyan Liang, Zhangquan Chen
Pages: 371-378
Published online on: 06 November 2019

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Article

Retinal proteomic evaluation of rats following streptozotocin‑injection using shotgun proteomics

Hiroko Otake, Tetushi Yamamoto, Saori Deguchi, Atushi Taga, Noriaki Nagai
Pages: 379-386
Published online on: 06 November 2019

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Article

A novel ATRX mutation causes Smith‑Fineman‑Myers syndrome in a Chinese family

Liangshan Li, Jing Yu, Xiao Zhang, Mengmeng Han, Wenmiao Liu, Hui Li, Shiguo Liu
Pages: 387-392
Published online on: 12 November 2019

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Article

Inhibition of CYP1B1 ameliorates cardiac hypertrophy induced by uremic toxin

Ying Zhang, Shaobo Wang, Yinghui Huang, Ke Yang, Yong Liu, Xianjin Bi, Chi Liu, Jiachuan Xiong, Bo Zhang, Jinghong Zhao, Ling Nie
Pages: 393-404
Published online on: 11 November 2019

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Article

Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats

Qingxiao Hong, Jing Liu, Zi Lin, Dingding Zhuang, Wenjin Xu, Zemin Xu, Miaojun Lai, Huaqiang Zhu, Wenhua Zhou, Huifen Liu
Pages: 405-412
Published online on: 22 November 2019

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Article

LncRNA ANCR downregulates hypoxia‑inducible factor 1α and inhibits the growth of HPV‑negative cervical squamous cell carcinoma under hypoxic conditions

Weiwei Ta, Yao Zhang, Shangdi Zhang, Pengfei Sun
Pages: 413-419
Published online on: 05 November 2019

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Article

Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals

Huahui Zhang, Tao Xie, Yongjie Shui, Yiying Qi
Pages: 420-428
Published online on: 06 November 2019

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Article

Lipoxin A4 attenuates hyperoxia‑induced lung epithelial cell injury via the upregulation of heme oxygenase‑1 and inhibition of proinflammatory cytokines

Yan‑Yan Luo, Sheng‑Hua Wu, Hong‑Yan Lu, Bing‑Jie Li, Shu‑Jun Li, Zhong‑Yi Sun, Rui Jin, Xiao‑Qing Chen
Pages: 429-437
Published online on: 15 November 2019

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Article

Identification of a novel pathogenic mutation of the MYH3 gene in a family with distal arthrogryposis type 2B

Wen‑Bo Wang, Ling‑Chi Kong, Rong‑Tai Zuo, Qing‑Lin Kang
Pages: 438-444
Published online on: 15 November 2019

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Article

IDO inhibitor synergized with radiotherapy to delay tumor growth by reversing T cell exhaustion

Meng Liu, Ziyang Li, Weirong Yao, Xiaoping Zeng, Lingyun Wang, Jiao Cheng, Bingyu Ma, Ruiqian Zhang, Weiping Min, Hongmei Wang
Pages: 445-453
Published online on: 12 November 2019

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Article

Blueberry anthocyanin‑enriched extract ameliorates transverse aortic constriction‑induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in mice

Weiqing Hu, Wenyue Wang, Qing Ma, Tao Liu, Jiefeng Zhang, Jicun Zhang
Pages: 454-462
Published online on: 06 November 2019

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Article

Protective effect of pyrrolidine dithiocarbamate on isoniazid/rifampicin‑induced liver injury in rats

Xue He, Yulin Song, Li Wang, Jianming Xu
Pages: 463-469
Published online on: 12 November 2019

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Article

Mechanical stress promotes biological functions of C2C12 myoblasts by activating PI3K/AKT/mTOR signaling pathway

Yu Da, Yongbin Mou, Mengjia Wang, Xiao Yuan, Fuhua Yan, Weidong Lan, Fang Zhang
Pages: 470-477
Published online on: 11 November 2019

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Article

rhBMP‑7 suppresses TGF‑β1‑induced endothelial to mesenchymal transition in circulating endothelial cells by regulating Smad5

Weili Ge, Yafei Mi, Shasha Xu, Tao Li, Yifei Lu, Jianjun Jiang
Pages: 478-484
Published online on: 21 November 2019

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Article

Organic anion transporting polypeptide 1A2 mediates fentanyl uptake in cultured cells

Xing‑Chen Huo, Hui‑Wen Yang, Li‑Hua Huang, Fan Zhang, Zi‑Ye Pan, Qin Liao
Pages: 485-492
Published online on: 05 November 2019

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Article

Brassicaphenanthrene A from Brassica rapa protects HT22 neuronal cells through the regulation of Nrf2‑mediated heme oxygenase‑1 expression

Hwan Lee, Wonmin Ko, Anisuzzaman Chowdhury, Bin Li, Sam Cheol Kim, Hyuncheol Oh, Youn‑Chul Kim, Eun‑Rhan Woo, Nam‑In Baek, Dong‑Sung Lee
Pages: 493-500
Published online on: 19 November 2019

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Article

Differentiation potential and functional properties of a CD34‑CD133+ subpopulation of endothelial progenitor cells

Katrin Bachelier, Carolin Bergholz, Erik B. Friedrich
Pages: 501-507
Published online on: 20 November 2019

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Article

Kai‑Xin‑San suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression

Yuan Hu, Xianzhe Dong, Tianyi Zhang, Hongming Ma, Wenshan Yang, Yichen Wang, Ping Liu, Yibang Chen
Pages: 508-516
Published online on: 06 November 2019

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Article Open Access

A novel gross deletion and breakpoint junction sequence analysis of ATP7B in a Chinese family with Wilson disease using next‑generation sequencing and Sanger sequencing

Wei‑Liang Liu, Fang Li, Lu Liu, Wei Chen, Zhi‑Xu He, Hao Gu, Rong Ai
Pages: 517-523
Published online on: 20 November 2019

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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Retraction Open Access

[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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