1
|
Villate O, Turatsinze JV, Mascali LG,
Grieco FA, Nogueira TC, Cunha DA, Nardelli TR, Sammeth M, Salunkhe
VA, Esguerra JL, et al: Nova1 is a master regulator of alternative
splicing in pancreatic beta cells. Nucleic Acids Res.
42:11818–11830. 2014. View Article : Google Scholar : PubMed/NCBI
|
2
|
Yoon SO, Kim EK, Lee M, Jung WY, Lee H,
Kang Y, Jang YJ, Hong SW, Choi SH and Yang WI: NOVA1 inhibition by
miR-146b-5p in the remnant tissue microenvironment defines occult
residual disease after gastric cancer removal. Oncotarget.
7:2475–2495. 2016. View Article : Google Scholar : PubMed/NCBI
|
3
|
Zhi F, Wang Q, Deng D, Shao N, Wang R, Xue
L, Wang S, Xia X and Yang Y: miR-181b-5p downregulates NOVA1 to
suppress proliferation, migration and invasion and promote
apoptosis in astrocytoma. PLoS One. 9:e1091242014. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kim EK, Yoon SO, Jung WY, Lee H, Kang Y,
Jang YJ, Hong SW, Choi SH and Yang WI: Implications of NOVA1
suppression within the microenvironment of gastric cancer:
Association with immune cell dysregulation. Gastric Cancer.
20:438–447. 2017. View Article : Google Scholar : PubMed/NCBI
|
5
|
Shen B, Zhang Y, Yu S, Yuan Y, Zhong Y, Lu
J and Feng J: MicroRNA-339, an epigenetic modulating target is
involved in human gastric carcinogenesis through targeting NOVA1.
FEBS Lett. 589:3205–3211. 2015. View Article : Google Scholar : PubMed/NCBI
|
6
|
Störchel PH, Thümmler J, Siegel G,
Aksoy-Aksel A, Zampa F, Sumer S and Schratt G: A large-scale
functional screen identifies Nova1 and Ncoa3 as regulators of
neuronal miRNA function. EMBO J. 34:2237–2254. 2015. View Article : Google Scholar : PubMed/NCBI
|
7
|
Browne G, Taipaleenmäki H, Stein GS, Stein
JL and Lian JB: MicroRNAs in the control of metastatic bone
disease. Trends Endocrinol Metab. 25:320–327. 2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Vimalraj S, Miranda P, Ramyakrishna B and
Selvamurugan N: Regulation of breast cancer and bone metastasis by
microRNAs. Dis Markers. 35:369–387. 2013. View Article : Google Scholar : PubMed/NCBI
|
9
|
Ding L, Zhang S, Xu M, Zhang R, Sui P and
Yang Q: MicroRNA-27a contributes to the malignant behavior of
gastric cancer cells by directly targeting PH domain and
leucine-rich repeat protein phosphatase 2. J Exp Clin Cancer Res.
36:452017. View Article : Google Scholar : PubMed/NCBI
|
10
|
Liu T, Tang H, Lang Y, Liu M and Li X:
MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by
targeting prohibitin. Cancer Lett. 273:233–242. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Park JL, Kim M, Song KS, Kim SY and Kim
YS: Cell-free miR-27a, a potential diagnostic and prognostic
biomarker for gastric cancer. Genomics Inform. 13:70–75. 2015.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Huang D, Wang H, Liu R, Li H, Ge S, Bai M,
Deng T, Yao G and Ba Y: miRNA27a is a biomarker for predicting
chemosensitivity and prognosis in metastatic or recurrent gastric
cancer. J Cell Biochem. 115:549–556. 2014. View Article : Google Scholar : PubMed/NCBI
|
13
|
Danza K, Silvestris N, Simone G, Signorile
M, Saragoni L, Brunetti O, Monti M, Mazzotta A, De Summa S, Mangia
A and Tommasi S: Role of miR-27a, miR-181a and miR-20b in gastric
cancer hypoxia-induced chemoresistance. Cancer Biol Ther.
17:400–406. 2016. View Article : Google Scholar : PubMed/NCBI
|
14
|
Zhao Q, Li Y, Tan BB, Fan LQ, Yang PG and
Tian Y: HIF-1α induces multidrug resistance in gastric cancer cells
by inducing miR-27a. PLoS One. 10:e01327462015. View Article : Google Scholar : PubMed/NCBI
|
15
|
Zhao X, Yang L and Hu J: Down-regulation
of miR-27a might inhibit proliferation and drug resistance of
gastric cancer cells. J Exp Clin Cancer Res. 30:552011. View Article : Google Scholar : PubMed/NCBI
|
16
|
Wang Z, Li Y, Ahmad A, Azmi AS, Kong D,
Banerjee S and Sarkar FH: Targeting miRNAs involved in cancer stem
cell and EMT regulation: An emerging concept in overcoming drug
resistance. Drug Resist Updat. 13:109–118. 2010. View Article : Google Scholar : PubMed/NCBI
|
17
|
Fan Y, Shen B, Tan M, Mu X, Qin Y, Zhang F
and Liu Y: TGF-β-induced upregulation of malat1 promotes bladder
cancer metastasis by associating with suz12. Clin Cancer Res.
20:1531–1541. 2014. View Article : Google Scholar : PubMed/NCBI
|
18
|
Washington K: 7th edition of the AJCC
cancer staging manual: Stomach. Ann Surg Oncol. 17:3077–3079. 2010.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Yang F, Bi J, Xue X, Zheng L, Zhi K, Hua J
and Fang G: Up-regulated long non-coding RNA H19 contributes to
proliferation of gastric cancer cells. FEBS J. 279:3159–3165. 2012.
View Article : Google Scholar : PubMed/NCBI
|
20
|
Liao XH, Lu DL, Wang N, Liu LY, Wang Y, Li
YQ, Yan TB, Sun XG, Hu P and Zhang TC: Estrogen receptor α mediates
proliferation of breast cancer MCF-7 cells via a
p21/PCNA/E2F1-dependent pathway. FEBS J. 281:927–942. 2014.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Betel D, Wilson M, Gabow A, Marks DS and
Sander C: The microRNA.org resource: Targets and expression.
Nucleic Acids Res. 36((Database Issue)): D149–D153. 2008.PubMed/NCBI
|
22
|
Riemenschneider MJ, Hirblinger M,
Vollmann-Zwerenz A, Hau P, Proescholdt MA, Jaschinski F,
Rothhammer-Hampl T, Wosikowski K, Janicot M and Leo E: TGF-β
isoforms in cancer: Immunohistochemical expression and
Smad-pathway-activity-analysis in thirteen major tumor types with a
critical appraisal of antibody specificity and immunohistochemistry
assay validity. Oncotarget. 6:26770–26781. 2015. View Article : Google Scholar : PubMed/NCBI
|
23
|
Liu L, Yu X, Guo X, Tian Z, Su M, Long Y,
Huang C, Zhou F, Liu M, Wu X and Wang X: miR-143 is downregulated
in cervical cancer and promotes apoptosis and inhibits tumor
formation by targeting Bcl-2. Mol Med Rep. 5:753–760.
2012.PubMed/NCBI
|
24
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Tsuji T, Ibaragi S and Hu GF:
Epithelial-mesenchymal transition and cell cooperativity in
metastasis. Cancer Res. 69:7135–7139. 2009. View Article : Google Scholar : PubMed/NCBI
|
26
|
Gavert N and Ben-Ze'ev A:
Epithelial-mesenchymal transition and the invasive potential of
tumors. Trends Mol Med. 14:199–209. 2008. View Article : Google Scholar : PubMed/NCBI
|
27
|
Zavadil J, Bitzer M, Liang D, Yang YC,
Massimi A, Kneitz S, Piek E and Bottinger EP: Genetic programs of
epithelial cell plasticity directed by transforming growth
factor-beta. Proc Natl Acad Sci USA. 98:6686–6691. 2001. View Article : Google Scholar : PubMed/NCBI
|
28
|
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan
A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, et al: The
epithelial-mesenchymal transition generates cells with properties
of stem cells. Cell. 133:704–715. 2008. View Article : Google Scholar : PubMed/NCBI
|
29
|
Busch T, Armacki M, Eiseler T, Joodi G,
Temme C, Jansen J, von Wichert G, Omary MB, Spatz J and Seufferlein
T: Keratin 8 phosphorylation regulates keratin reorganization and
migration of epithelial tumor cells. J Cell Sci. 125:2148–2159.
2012. View Article : Google Scholar : PubMed/NCBI
|
30
|
Hur K, Toiyama Y, Takahashi M, Balaguer F,
Nagasaka T, Koike J, Hemmi H, Koi M, Boland CR and Goel A:
MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT)
in human colorectal cancer metastasis. Gut. 62:1315–1326. 2013.
View Article : Google Scholar : PubMed/NCBI
|
31
|
Zhu L, Wang Z, Fan Q, Wang R and Sun Y:
microRNA-27a functions as a tumor suppressor in esophageal squamous
cell carcinoma by targeting KRAS. Oncol Rep. 31:280–286. 2014.
View Article : Google Scholar : PubMed/NCBI
|
32
|
Salah Z, Arafeh R, Maximov V, Galasso M,
Khawaled S, Abou-Sharieha S, Volinia S, Jones KB, Croce CM and
Aqeilan RI: miR-27a and miR-27a* contribute to metastatic
properties of osteosarcoma cells. Oncotarget. 6:4920–4935. 2015.
View Article : Google Scholar : PubMed/NCBI
|
33
|
Tian Y, Fu S, Qiu GB, Xu ZM, Liu N, Zhang
XW, Chen S, Wang Y, Sun KL and Fu WN: MicroRNA-27a promotes
proliferation and suppresses apoptosis by targeting PLK2 in
laryngeal carcinoma. BMC Cancer. 14:6782014. View Article : Google Scholar : PubMed/NCBI
|
34
|
Zhou S, Huang Q, Zheng S, Lin K, You J and
Zhang X: miR-27a regulates the sensitivity of breast cancer cells
to cisplatin treatment via BAK-SMAC/DIABLO-XIAP axis. Tumour Biol.
37:6837–6845. 2016. View Article : Google Scholar : PubMed/NCBI
|
35
|
Liang J, Tang J, Shi H, Li H, Zhen T, Duan
J, Kang L, Zhang F, Dong Y and Han A: miR-27a-3p targeting RXRα
promotes colorectal cancer progression by activating Wnt/β-catenin
pathway. Oncotarget. 8:82991–83008. 2017.PubMed/NCBI
|
36
|
Zhou L, Liang X, Zhang L, Yang L, Nagao N,
Wu H, Liu C, Lin S, Cai G and Liu J: miR-27a-3p functions as an
oncogene in gastric cancer by targeting BTG2. Oncotarget.
7:51943–51954. 2016.PubMed/NCBI
|
37
|
Xu W, Liu M, Peng X, Zhou P, Zhou J, Xu K,
Xu H and Jiang S: miR-24-3p and miR-27a-3p promote cell
proliferation in glioma cells via cooperative regulation of MXI1.
Int J Oncol. 42:757–766. 2013. View Article : Google Scholar : PubMed/NCBI
|
38
|
Wu XZ, Wang KP, Song HJ, Xia JH, Jiang Y
and Wang YL: miR-27a-3p promotes esophageal cancer cell
proliferation via F-box and WD repeat domain-containing 7 (FBXW7)
suppression. Int J Clin Exp Med. 8:15556–15562. 2015.PubMed/NCBI
|
39
|
Peng Z, Wang CX, Fang EH, Wang GB and Tong
Q: Role of epithelial-mesenchymal transition in gastric cancer
initiation and progression. World J Gastroenterol. 20:5403–5410.
2014. View Article : Google Scholar : PubMed/NCBI
|