|
1
|
Maximov VV, Akkawi R, Khawaled S, Salah Z,
Jaber L, Barhoum A, Or O, Galasso M, Kurek KC, Yavin E and Aqeilan
RI: MiR-16-1-3p and miR-16-2-3p possess strong tumor suppressive
and antimetastatic properties in osteosarcoma. Int J Cancer.
145:3052–3063. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hsu MJ, Peng SF, Chueh FS, Tsai CH, Tsai
FJ, Huang CY, Tang CH, Yang JS, Hsu YM, Huang WW and Chung JG:
Lupeol suppresses migration and invasion via p38/MAPK and PI3K/Akt
signaling pathways in human osteosarcoma U-2 OS cells. Biosci
Biotechnol Biochem. 83:1729–1739. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ma H, Su R, Feng H, Guo Y and Su G: Long
noncoding RNA UCA1 promotes osteosarcoma metastasis through
CREB1-mediated epithelial-mesenchymal transition and activating
PI3K/AKT/mTOR pathway. J Bone Oncol. 16:1002282019. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Wang Y, Huang H and Li Y: Knocking down
miR-384 promotes growth and metastasis of osteosarcoma MG63 cells
by targeting SLBP. Artif Cells Nanomed Biotechnol. 47:1458–1465.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Chen JK, Peng SF, Lai KC, Liu HC, Huang
YP, Lin CC, Huang AC, Chueh FS and Chung JG: Fistein suppresses
human osteosarcoma U-2 OS cell migration and invasion via affecting
FAK, uPA and NF-κB signaling pathway in vitro. In vivo. 33:801–810.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lau D, Elezagic D, Hermes G, Mörgelin M,
Wohl AP, Koch M, Hartmann U, Höllriegl S, Wagener R, Paulsson M, et
al: The cartilage-specific lectin C-type lectin domain family 3
member A (CLEC3A) enhances tissue plasminogen activator-mediated
plasminogen activation. J Biol Chem. 293:203–214. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Wang Y, Lv Y, Liu TS, Yan WD, Chen LY, Li
ZH, Piao YS, An RB, Lin ZH and Ren XS: Cordycepin suppresses cell
proliferation and migration by targeting CLEC2 in human gastric
cancer cells via Akt signaling pathway. Life Sci. 223:110–119.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ni J, Peng Y, Yang FL, Xi X, Huang XW and
He C: Overexpression of CLEC3A promotes tumor progression and poor
prognosis in breast invasive ductal cancer. Onco Targets Ther.
11:3303–3312. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ho XD, Phung P, Q Le V, H Nguyen V,
Reimann E, Prans E, Kõks G, Maasalu K, Le NT, H Trinh L, et al:
Whole transcriptome analysis identifies differentially regulated
networks between osteosarcoma and normal bone samples. Exp Biol Med
(Maywood). 242:1802–1811. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Sepulveda JL: Using R and Bioconductor in
clinical genomics and transcriptomics. J Mol Diagn. 22:3–20. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Livak JK and Schmittgen TD: Analysis of
relative gene expression data using quantitative PCR and the 2
(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Heng M, Gupta A, Chung PW, Healey JH,
Vaynrub M, Rose PS, Houdek MT, Lin PP, Bishop AJ, Hornicek FJ, et
al: The role of chemotherapy and radiotherapy in localized
extraskeletal osteosarcoma. Eur J Cancer. 125:130–141. 2010.
View Article : Google Scholar
|
|
13
|
Pan C, Liu Q and Wu X: HIF1α
a/miR-520a-3p/AKT1/mTOR feedback promotes the proliferation and
glycolysis of gastric cancer cells. Cancer Manag Res.
11:10145–10156. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhang X, Wang S, Wang H, Cao J, Huang X,
Chen Z, Xu P, Sun G, Xu J, Lv J and Xu Z: Circular RNA circNRIP1
acts as a microRNA-149-5p sponge to promote gastric cancer
progression via the AKT1/mTOR pathway. Mol Cancer. 18:202019.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liao Z, She C, Ma L, Sun Z, Li P, Zhang X,
Wang P and Li W: KDELR2 promotes glioblastoma tumorigenesis
targeted by HIF1a via mTOR signaling pathway. Cell Mol Neurobiol.
39:1207–1215. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Prater S and McKeon B: Cancer,
Osteosarcoma. StatPearls Publishing; Treasure Island, FL: 2019
|
|
17
|
Imura Y, Takenaka S, Kakunaga S, Nakai T,
Wakamatsu T, Outani H, Tanaka T, Tamiya H, Oshima K, Hamada K, et
al: Survival analysis of elderly patients with osteosarcoma. Int
Orthop. 43:1741–1747. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhang Y, Yang J, Zhao N, Wang C, Kamar S,
Zhou Y, He Z, Yang J, Sun B, Shi X, et al: Progress in the
chemotherapeutic treatment of osteosarcoma. Oncol Lett.
16:6228–6237. 2018.PubMed/NCBI
|
|
19
|
Mayer S, Raulf MK and Lepenies B: C-type
lectins: Their network and roles in pathogen recognition and
immunity. Histochem Cell Biol. 147:223–237. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ding D, Yao Y, Zhang S, Su C and Zhang Y:
C-type lectins facilitate tumor metastasis. Oncol Lett. 13:13–21.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Xiong Y, Liu L, Xia Y, Wang J, Xi W, Bai
Q, Qu Y, Long Q, Xu J and Guo J: High CLEC-2 expression associates
with unfavorable postoperative prognosis of patients with clear
cell renal cell carcinoma. Oncotarget. 7:63661–63668. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Osada M, Inoue O, Ding G, Shirai T, Ichise
H, Hirayama K, Takano K, Yatomi Y, Hirashima M, Fujii H, et al:
Platelet activation receptor CLEC-2 regulates blood/lymphatic
vessel separation by inhibiting proliferation, migration, and tube
formation of lymphatic endothelial cells. J Biol Chem.
287:22241–22252. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Karlsson C, Dehne T, Lindahl A, Brittberg
M, Pruss A, Sittinger M and Ringe J: Genome-wide expression
profiling reveals new candidate genes associated with
osteoarthritis. Osteoarthritis Cartilage. 18:581–592. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Perry JA, Kiezun A, Tonzi P, Van Allen EM,
Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS,
et al: Complementary genomic approaches highlight the PI3K/mTOR
pathway as a common vulnerability in osteosarcoma. Proc Natl Acad
Sci USA. 111:E5564–E5573. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhang J, Yu XH, Yan YG, Wang C and Wang
WJ: PI3K/Akt signaling in osteosarcoma. Clin Chim Acta.
444:182–192. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hu K, Dai HB and Qiu ZL: mTOR signaling in
osteosarcoma: Oncogenesis and therapeutic aspects (Review). Oncol
Rep. 36:1219–1225. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Jiang C, Ma Z, Zhang G, Yang X, Du Q and
Wang W: CSNK2A1 Promotes gastric cancer invasion through the
PI3K-Akt-mTOR signaling pathway. Cancer Manag Res. 11:10135–10143.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Li ZQ, Qu M, Wan HX, Wang H, Deng Q and
Zhang Y: FOXK1 promotes malignant progression of breast cancer by
activating PI3K/AKT/mTOR signaling pathway. Eur Rev Med Pharmacol
Sci. 23:9978–9987. 2019.PubMed/NCBI
|
|
29
|
Qian J and Rankin EB: Hypoxia-induced
phenotypes that mediate tumor heterogeneity. Adv Exp Med Biol.
1136:43–55. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Hayashi Y, Yokota A, Harada H and Huang G:
Hypoxia/pseudohypoxia-mediated activation of hypoxia-inducible
factor-1α in cancer. Cancer Sci. 110:1510–1517. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Thomas LW and Ashcroft M: Exploring the
molecular interface between hypoxia-inducible factor signalling and
mitochondria. Cell Mol Life Sci. 76:1759–1777. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Du Y, Long Q, Zhang L, Shi Y, Liu X, Li X,
Guan B, Tian Y, Wang X, Li L and He D: Curcumin inhibits
cancer-associated fibroblast-driven prostate cancer invasion
through MAOA/mTOR/HIF-1α signaling. Int J Oncol. 47:2064–2072.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Woo YM, Shin Y, Lee EJ, Lee S, Jeong SH,
Kong HK, Park EY, Kim HK, Han J, Chang M and Park JH: Inhibition of
aerobic glycolysis represses Akt/mTOR/HIF-1α axis and restores
tamoxifen sensitivity in antiestrogen-resistant breast cancer
cells. PLoS One. 10:e01322852015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang Y, Huang Y, Liu H, Su D, Luo F and
Zhou F: Long noncoding RNA CDKN2B-AS1 interacts with miR-411-3p to
regulate ovarian cancer in vitro and In vivo through
HIF-1a/VEGF/P38 pathway. Biochem Biophys Res Commun. 514:44–50.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Sadlecki P, Bodnar M, Grabiec M, Marszalek
A, Walentowicz P, Sokup A, Zegarska J and Walentowicz-Sadlecka M:
The role of Hypoxia-inducible factor-1α, glucose transporter-1,
(GLUT-1) and carbon anhydrase IX in endometrial cancer patients.
BioMed research international. 2014:6168502014. View Article : Google Scholar : PubMed/NCBI
|
