Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
May-2020 Volume 21 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2020 Volume 21 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

The role of granulocyte colony‑stimulating factor in breast cancer development: A review

  • Authors:
    • Li Liu
    • Yangyang Liu
    • Xiaohua Yan
    • Chong Zhou
    • Xiangyang Xiong
  • View Affiliations / Copyright

    Affiliations: Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Nanchang University, Nanchang, Jiangxi 330006, P.R. China, Department of Anesthesiology, First Clinical Medical College, School of Medicine, Nanchang University, Nanchang, Jiangxi 330006, P.R. China
    Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2019-2029
    |
    Published online on: March 10, 2020
       https://doi.org/10.3892/mmr.2020.11017
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Granulocyte‑colony‑stimulating factor (G‑CSF) is a member of the hematopoietic growth factor family that primarily affects the neutrophil lineage. G‑CSF serves as a powerful mobilizer of peripheral blood stem cells and recombinant human G‑CSF (rhG‑CSF) has been used to treat granulocytopenia and neutropenia after chemotherapy for cancer patients. However, recent studies have found that G‑CSF plays an important role in cancer progression. G‑CSF expression is increased in different types of cancer cells, such as lung cancer, gastric cancer, colorectal cancer, invasive bladder carcinoma, glioma and breast cancer. However, it is unclear whether treatment with G‑CSF has an adverse effect. The current review provides an overview of G‑CSF in malignant breast cancer development and the data presented in this review are expected to provide new ideas for cancer therapy.
View Figures

Figure 1

Figure 2

View References

1 

Bradley TR and Metcalf D: The growth of mouse bone marrow cells in vitro. Aust J Exp Biol Med Sci. 44:287–299. 1966. View Article : Google Scholar : PubMed/NCBI

2 

Ichikawa Y, Pluznik DH and Sachs L: In vitro control of the development of macrophage and granulocyte colonies. Proc Natl Acad Sci USA. 56:488–495. 1966. View Article : Google Scholar : PubMed/NCBI

3 

Stanley ER and Heard PM: Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells. J Biol Chem. 252:4305–4312. 1977.PubMed/NCBI

4 

Burgess AW, Camakaris J and Metcalf D: Purification and properties of colony-stimulating factor from mouse lung-conditioned medium. J Biol Chem. 252:1998–2003. 1977.PubMed/NCBI

5 

Nicola NA, Metcalf D, Matsumoto M and Johnson GR: Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor. J Biol Chem. 258:9017–9023. 1983.PubMed/NCBI

6 

Ihle JN, Keller J, Henderson L, Klein F and Palaszynski E: Procedures for the purification of interleukin 3 to homogeneity. J Immunol. 129:2431–2436. 1982.PubMed/NCBI

7 

Metcalf D: The colony stimulating factors. Discovery, development, and clinical applications. Cancer. 65:2185–2195. 1990. View Article : Google Scholar : PubMed/NCBI

8 

Fukunaga R, Ishizaka-Ikeda E and Nagata S: Purification and characterization of the receptor for murine granulocyte colony-stimulating factor. J Biol Chem. 265:14008–14015. 1990.PubMed/NCBI

9 

Demetri GD and Griffin JD: Granulocyte colony-stimulating factor and its receptor. Blood. 78:2791–2808. 1991. View Article : Google Scholar : PubMed/NCBI

10 

Bendall LJ and Bradstock KF: G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent. Cytokine Growth Factor Rev. 25:355–367. 2014. View Article : Google Scholar : PubMed/NCBI

11 

Mitchell S, Li X, Woods M, Garcia J, Hebard-Massey K, Barron R and Samuel M: Comparative effectiveness of granulocyte colony-stimulating factors to prevent febrile neutropenia and related complications in cancer patients in clinical practice: A systematic review. J Oncol Pharm Pract. 22:702–716. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Kawano M, Mabuchi S, Matsumoto Y, Sasano T, Takahashi R, Kuroda H, Kozasa K, Hashimoto K, Isobe A, Sawada K, et al: The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer. Sci Rep. 5:182172015. View Article : Google Scholar : PubMed/NCBI

13 

Okazaki T, Ebihara S, Asada M, Kanda A, Sasaki H and Yamaya M: Granulocyte colony-stimulating factor promotes tumor angiogenesis via increasing circulating endothelial progenitor cells and Gr1+CD11b+ cells in cancer animal models. Int Immunol. 18:1–9. 2006. View Article : Google Scholar : PubMed/NCBI

14 

Shojaei F, Wu X, Qu X, Kowanetz M, Yu L, Tan M, Meng YG and Ferrara N: G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc Natl Acad Sci USA. 106:6742–6747. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Demers M, Krause DS, Schatzberg D, Martinod K, Voorhees JR, Fuchs TA, Scadden DT and Wagner DD: Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis. Proc Natl Acad Sci USA. 109:13076–13081. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Gomes T, Várady CBS, Lourenço AL, Mizurini DM, Rondon AMR, Leal AC, Gonçalves BS, Bou-Habib DC, Medei E and Monteiro RQ: IL-1β blockade attenuates thrombosis in a neutrophil extracellular trap-dependent breast cancer model. Front Immunol. 10:20882019. View Article : Google Scholar : PubMed/NCBI

17 

Hollmén M, Karaman S, Schwager S, Lisibach A, Christiansen AJ, Maksimow M, Varga Z, Jalkanen S and Detmar M: G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. OncoImmunology. 5:e11151772015. View Article : Google Scholar : PubMed/NCBI

18 

Kanda N, Fukushige S, Murotsu T, Yoshida MC, Tsuchiya M, Asano S, Kaziro Y and Nagata S: Human gene coding for granulocyte-colony stimulating factor is assigned to the q21-q22 region of chromosome 17. Somat Cell Mol Genet. 13:679–684. 1987. View Article : Google Scholar : PubMed/NCBI

19 

Tsuchiya M, Kaziro Y and Nagata S: The chromosomal gene structure for murine granulocyte colony-stimulating factor. Eur J Biochem. 165:7–12. 1987. View Article : Google Scholar : PubMed/NCBI

20 

Shannon MF, Pell LM, Lenardo MJ, Kuczek ES, Occhiodoro FS, Dunn SM and Vadas MA: A novel tumor necrosis factor-responsive transcription factor which recognizes a regulatory element in hemopoietic growth factor genes. Mol Cell Biol. 10:2950–2959. 1990. View Article : Google Scholar : PubMed/NCBI

21 

Nagata S, Tsuchiya M, Asano S, Yamamoto O, Hirata Y, Kubota N, Oheda M, Nomura H and Yamazaki T: The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor. EMBO J. 5:575–581. 1986. View Article : Google Scholar : PubMed/NCBI

22 

He RL, Zhou J, Hanson CZ, Chen J, Cheng N and Ye RD: Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2. Blood. 113:429–437. 2009. View Article : Google Scholar : PubMed/NCBI

23 

Himes SR, Coles LS, Katsikeros R, Lang RK and Shannon MF: HTLV-1 tax activation of the GM-CSF and G-CSF promoters requires the interaction of NF-kB with other transcription factor families. Oncogene. 8:3189–3197. 1993.PubMed/NCBI

24 

Nishizawa M and Nagata S: Regulatory elements responsible for inducible expression of the granulocyte colony-stimulating factor gene in macrophages. Mol Cell Biol. 10:2002–2011. 1990. View Article : Google Scholar : PubMed/NCBI

25 

Nagata S, Tsuchiya M, Asano S, Kaziro Y, Yamazaki T, Yamamoto O, Hirata Y, Kubota N, Oheda M, Nomura H, et al: Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor. Nature. 319:415–418. 1986. View Article : Google Scholar : PubMed/NCBI

26 

Akira S, Isshiki H, Sugita T, Tanabe O, Kinoshita S, Nishio Y, Nakajima T, Hirano T and Kishimoto T: A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J. 9:1897–1906. 1990. View Article : Google Scholar : PubMed/NCBI

27 

Mitchell PJ and Tjian R: Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science. 245:371–378. 1989. View Article : Google Scholar : PubMed/NCBI

28 

Shannon MF, Coles LS, Fielke RK, Goodall GJ, Lagnado CA and Vadas MA: Three essential promoter elements mediate tumour necrosis factor and interleukin-1 activation of the granulocyte-colony stimulating factor gene. Growth Factors. 7:181–193. 1992. View Article : Google Scholar : PubMed/NCBI

29 

Hareng L, Meergans T, von Aulock S, Volk HD and Hartung T: Cyclic AMP increases endogenous granulocyte colony-stimulating factor formation in monocytes and THP-1 macrophages despite attenuated TNF-alpha formation. Eur J Immunol. 33:2287–2296. 2003. View Article : Google Scholar : PubMed/NCBI

30 

Nishizawa M, Tsuchiya M, Watanabe-Fukunaga R and Nagata S: Multiple elements in the promoter of granulocyte colony-stimulating factor gene regulate its constitutive expression in human carcinoma cells. J Biol Chem. 265:5897–5902. 1990.PubMed/NCBI

31 

Asano M, Nishizawa M and Nagata S: Three individual regulatory elements of the promoter positively activate the transcription of the murine gene encoding granulocyte colony-stimulating factor. Gene. 107:241–246. 1991. View Article : Google Scholar : PubMed/NCBI

32 

Brown CY, Lagnado CA and Goodall GJ: A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements. Proc Natl Acad Sci USA. 93:13721–13725. 1996. View Article : Google Scholar : PubMed/NCBI

33 

Arakawa T, Horan TP, Leong K, Prestrelski SJ, Narhi LO and Hu S: Structure and activity of granulocyte colony-stimulating factor derived from CHO cells containing cDNA coding for alternatively spliced sequences. Arch Biochem Biophys. 316:285–289. 1995. View Article : Google Scholar : PubMed/NCBI

34 

Souza LM, Boone TC, Gabrilove J, Lai PH, Zsebo KM, Murdock DC, Chazin VR, Bruszewski J, Lu H, Chen KK, et al: Recombinant human granulocyte colony-stimulating factor: Effects on normal and leukemic myeloid cells. Science. 232:61–65. 1986. View Article : Google Scholar : PubMed/NCBI

35 

Kubota N, Orita T, Hattori K, Oh-eda M, Ochi N and Yamazaki T: Structural characterization of natural and recombinant human granulocyte colony-stimulating factors. J Biochem. 107:486–492. 1990. View Article : Google Scholar : PubMed/NCBI

36 

Hill CP, Osslund TD and Eisenberg D: The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors. Proc Natl Acad Sci USA. 90:5167–5171. 1993. View Article : Google Scholar : PubMed/NCBI

37 

Senda T, Shimazu T, Matsuda S, Kawano G, Shimizu H, Nakamura KT and Mitsui Y: Three-dimensional crystal structure of recombinant murine interferon-beta. EMBO J. 11:3193–3201. 1992. View Article : Google Scholar : PubMed/NCBI

38 

Cheers C, Haigh AM, Kelso A, Metcalf D, Stanley ER and Young AM: Production of colony-stimulating factors (CSFs) during infection: Separate determinations of macrophage-, granulocyte-, granulocyte-macrophage-, and multi-CSFs. Infect Immun. 56:247–251. 1988. View Article : Google Scholar : PubMed/NCBI

39 

Vellenga E, Rambaldi A, Ernst TJ, Ostapovicz D and Griffin JD: Independent regulation of M-CSF and G-CSF gene expression in human monocytes. Blood. 71:1529–1532. 1988. View Article : Google Scholar : PubMed/NCBI

40 

Jones CE and Chan K: Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocyte-colony-stimulating factor by human airway epithelial cells. Am J Respir Cell Mol Biol. 26:748–753. 2002. View Article : Google Scholar : PubMed/NCBI

41 

Sano E, Ohashi K, Sato Y, Kashiwagi M, Joguchi A and Naruse N: A possible role of autogenous IFN-beta for cytokine productions in human fibroblasts. J Cell Biochem. 100:1459–1476. 2007. View Article : Google Scholar : PubMed/NCBI

42 

Jardin F, Vasse M, Debled M, Dominique S, Courville P, Callonnec F, Buchonnet G, Thiberville L and Tilly H: Intense paraneoplastic neutrophilic leukemoid reaction related to a G-CSF-secreting lung sarcoma. Am J Hematol. 80:243–245. 2005. View Article : Google Scholar : PubMed/NCBI

43 

Uemura Y, Kobayashi M, Nakata H, Kubota T, Saito T, Bandobashi K and Taguchi H: Role of protein kinase C in expression of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells. Int J Mol Med. 16:873–881. 2005.PubMed/NCBI

44 

Tachibana M, Miyakawa A, Uchida A, Murai M, Eguchi K, Nakamura K, Kubo A and Hata JI: Granulocyte colony-stimulating factor receptor expression on human transitional cell carcinoma of the bladder. Br J Cancer. 75:1489–1496. 1997. View Article : Google Scholar : PubMed/NCBI

45 

Nomura H, Imazeki I, Oheda M, Kubota N, Tamura M, Ono M, Ueyama Y and Asano S: Purification and characterization of human granulocyte colony-stimulating factor (G-CSF). EMBO J. 5:871–876. 1986. View Article : Google Scholar : PubMed/NCBI

46 

Chafe SC, Lou Y, Sceneay J, Vallejo M, Hamilton MJ, McDonald PC, Bennewith KL, Möller A and Dedhar S: Carbonic anhydrase IX promotes myeloid-derived suppressor cell mobilization and establishment of a metastatic niche by stimulating G-CSF production. Cancer Res. 75:996–1008. 2015. View Article : Google Scholar : PubMed/NCBI

47 

Lee CH, Lin SH, Chang SF, Chang PY, Yang ZP and Lu SC: Extracellular signal-regulated kinase 2 mediates the expression of granulocyte colony-stimulating factor in invasive cancer cells. Oncol Rep. 30:419–424. 2013. View Article : Google Scholar : PubMed/NCBI

48 

Park S, Kim ES, Noh DY, Hwang KT and Moon A: H-Ras-specific upregulation of granulocyte colony-stimulating factor promotes human breast cell invasion via matrix metalloproteinase-2. Cytokine. 55:126–133. 2011. View Article : Google Scholar : PubMed/NCBI

49 

Carvalho É, Hugo de Almeida V, Rondon AMR, Possik PA, Viola JPB and Monteiro RQ: Protease-activated receptor 2 (PAR2) upregulates granulocyte colony stimulating factor (G-CSF) expression in breast cancer cells. Biochem Biophys Res Commun. 504:270–276. 2018. View Article : Google Scholar : PubMed/NCBI

50 

Samineni S, Zhang Z and Shively JE: Carcinoembryonic antigen-related cell adhesion molecule 1 negatively regulates granulocyte colony-stimulating factor production by breast tumor-associated macrophages that mediate tumor angiogenesis. Int J Cancer. 133:394–407. 2013. View Article : Google Scholar : PubMed/NCBI

51 

Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, et al: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 18:632–644. 2016. View Article : Google Scholar : PubMed/NCBI

52 

Cosman D: The hematopoietin receptor superfamily. Cytokine. 5:95–106. 1993. View Article : Google Scholar : PubMed/NCBI

53 

Touw IP and van de Geijn GJ: Granulocyte colony-stimulating factor and its receptor in normal myeloid cell development, leukemia and related blood cell disorders. Front Biosci. 12:800–815. 2007. View Article : Google Scholar : PubMed/NCBI

54 

Avalos BR: Molecular analysis of the granulocyte colony-stimulating factor receptor. Blood. 88:761–777. 1996. View Article : Google Scholar : PubMed/NCBI

55 

Avalos BR, Parker JM, Ware DA, Hunter MG, Sibert KA and Druker BJ: Dissociation of the Jak kinase pathway from G-CSF receptor signaling in neutrophils. Exp Hematol. 25:160–168. 1997.PubMed/NCBI

56 

Pencik J, Pham HT, Schmoellerl J, Javaheri T, Schlederer M, Culig Z, Merkel O, Moriggl R, Grebien F and Kenner L: JAK-STAT signaling in cancer: From cytokines to non-coding genome. Cytokine. 87:26–36. 2016. View Article : Google Scholar : PubMed/NCBI

57 

Fan Z, Li Y, Zhao Q, Fan L, Tan B, Zuo J, Hua K and Ji Q: Highly expressed granulocyte colony-stimulating factor (G-CSF) and granulocyte colony-stimulating factor receptor (G-CSFR) in human gastric cancer leads to poor survival. Med Sci Monit. 24:1701–1711. 2018. View Article : Google Scholar : PubMed/NCBI

58 

Dwivedi P and Greis KD: Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies. Exp Hematol. 46:9–20. 2017. View Article : Google Scholar : PubMed/NCBI

59 

Fukui Y, Kawashima M, Kawaguchi K, Takeuchi M, Hirata M, Kataoka TR, Sakurai T, Kataoka M, Kanao S, Nakamoto Y, et al: Granulocyte-colony-stimulating factor-producing metaplastic carcinoma of the breast with significant elevation of serum interleukin-17 and vascular endothelial growth factor levels. Int Cancer Conf J. 7:107–113. 2018. View Article : Google Scholar : PubMed/NCBI

60 

Lawicki S, Czygier M, Omyła J and Szmitkowski M: The plasma levels of granulocyte-colony stimulating factor (G-CSF) and macrophage-colony stimulating factor (M-CSF) in breast cancer patients. Pol Arch Med Wewn. 116:749–755. 2006.(In Polish). PubMed/NCBI

61 

Ławicki S, Będkowska GE, Wojtukiewicz M and Szmitkowski M: Hematopoietic cytokines as tumor markers in breast malignancies. A multivariate analysis with ROC curve in breast cancer patients. Adv Med Sci. 58:207–215. 2013. View Article : Google Scholar : PubMed/NCBI

62 

Bordbar E, Malekzadeh M, Ardekani MT, Doroudchi M and Ghaderi A: Serum levels of G-CSF and IL-7 in Iranian breast cancer patients. Asian Pac J Cancer Prev. 13:5307–5312. 2012. View Article : Google Scholar : PubMed/NCBI

63 

Agresti R, Triulzi T, Sasso M, Ghirelli C, Aiello P, Rybinska I, Campiglio M, Sfondrini L, Tagliabue E and Bianchi F: Wound healing fluid reflects the inflammatory nature and aggressiveness of breast tumors. Cells. 8:82019. View Article : Google Scholar

64 

Wojtukiewicz MZ, Sierko E, Skalij P, Kamińska M, Zimnoch L, Brekken RA and Thorpe PE: Granulocyte-colony stimulating factor receptor, tissue factor, and VEGF-R bound VEGF in human breast cancer in loco. Adv Clin Exp Med. 25:505–511. 2016. View Article : Google Scholar : PubMed/NCBI

65 

Cao Y, Slaney CY, Bidwell BN, Parker BS, Johnstone CN, Rautela J, Eckhardt BL and Anderson RL: BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity. Cancer Res. 74:5091–5102. 2014. View Article : Google Scholar : PubMed/NCBI

66 

Kowanetz M, Wu X, Lee J, Tan M, Hagenbeek T, Qu X, Yu L, Ross J, Korsisaari N, Cao T, et al: Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes. Proc Natl Acad Sci USA. 107:21248–21255. 2010. View Article : Google Scholar : PubMed/NCBI

67 

Guo L, Chen G, Zhang W, Zhou L, Xiao T, Di X, Wang Y, Feng L and Zhang K: A high-risk luminal A dominant breast cancer subtype with increased mobility. Breast Cancer Res Treat. 175:459–472. 2019. View Article : Google Scholar : PubMed/NCBI

68 

Park J, Wysocki RW, Amoozgar Z, Maiorino L, Fein MR, Jorns J, Schott AF, Kinugasa-Katayama Y, Lee Y, Won NH, et al: Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med. 8:361ra1382016. View Article : Google Scholar : PubMed/NCBI

69 

Demers M and Wagner DD: Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression. OncoImmunology. 2:e229462013. View Article : Google Scholar : PubMed/NCBI

70 

Leal AC, Mizurini DM, Gomes T, Rochael NC, Saraiva EM, Dias MS, Werneck CC, Sielski MS, Vicente CP and Monteiro RQ: tumor-derived exosomes induce the formation of neutrophil extracellular traps: Implications for the establishment of cancer-associated thrombosis. Sci Rep. 7:64382017. View Article : Google Scholar : PubMed/NCBI

71 

Zhao CL, Zhang GP, Xiao ZZ, Ma ZK, Lei CP, Song SY, Feng YY, Zhao YC and Feng XS: Recombinant human granulocyte colony-stimulating factor promotes preinvasive and invasive estrogen receptor-positive tumor development in MMTV-erbB2 mice. J Breast Cancer. 18:126–133. 2015. View Article : Google Scholar : PubMed/NCBI

72 

Waight JD, Hu Q, Miller A, Liu S and Abrams SI: Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism. PLoS One. 6:e276902011. View Article : Google Scholar : PubMed/NCBI

73 

Espinoza-Sánchez NA, Vadillo E, Balandrán JC, Monroy-García A, Pelayo R and Fuentes-Pananá EM: Evidence of lateral transmission of aggressive features between different types of breast cancer cells. Int J Oncol. 51:1482–1496. 2017. View Article : Google Scholar : PubMed/NCBI

74 

Cavalloni G, Sarotto I, Pignochino Y, Gammaitoni L, Migliardi G, Sgro L, Piacibello W, Risio M, Aglietta M and Leone F: Granulocyte-colony stimulating factor upregulates ErbB2 expression on breast cancer cell lines and converts primary resistance to trastuzumab. Anticancer Drugs. 19:689–696. 2008. View Article : Google Scholar : PubMed/NCBI

75 

Pondé N, Brandão M, El-Hachem G, Werbrouck E and Piccart M: Treatment of advanced HER2-positive breast cancer: 2018 and beyond. Cancer Treat Rev. 67:10–20. 2018. View Article : Google Scholar : PubMed/NCBI

76 

Siegel RL, Miller KD and Jemal A: Cancer statistics, 2019. CA Cancer J Clin. 69:7–34. 2019. View Article : Google Scholar : PubMed/NCBI

77 

Motz GT and Coukos G: Deciphering and reversing tumor immune suppression. Immunity. 39:61–73. 2013. View Article : Google Scholar : PubMed/NCBI

78 

Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, Carbone DP and Gabrilovich DI: Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer. J Immunol. 166:678–689. 2001. View Article : Google Scholar : PubMed/NCBI

79 

Quail DF and Joyce JA: Microenvironmental regulation of tumor progression and metastasis. Nat Med. 19:1423–1437. 2013. View Article : Google Scholar : PubMed/NCBI

80 

Aliper AM, Frieden-Korovkina VP, Buzdin A, Roumiantsev SA and Zhavoronkov A: A role for G-CSF and GM-CSF in nonmyeloid cancers. Cancer Med. 3:737–746. 2014. View Article : Google Scholar : PubMed/NCBI

81 

Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL and Novitskiy SV: Development of aggressive pancreatic ductal adenocarcinomas depends on granulocyte colony stimulating factor secretion in carcinoma cells. Cancer Immunol Res. 5:718–729. 2017. View Article : Google Scholar : PubMed/NCBI

82 

Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ and Montero AJ: Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother. 58:49–59. 2009. View Article : Google Scholar : PubMed/NCBI

83 

Markowitz J, Wesolowski R, Papenfuss T, Brooks TR and Carson WE III: Myeloid-derived suppressor cells in breast cancer. Breast Cancer Res Treat. 140:13–21. 2013. View Article : Google Scholar : PubMed/NCBI

84 

Sceneay J, Chow MT, Chen A, Halse HM, Wong CS, Andrews DM, Sloan EK, Parker BS, Bowtell DD, Smyth MJ, et al: Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche. Cancer Res. 72:3906–3911. 2012. View Article : Google Scholar : PubMed/NCBI

85 

Lin EY, Nguyen AV, Russell RG and Pollard JW: Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med. 193:727–740. 2001. View Article : Google Scholar : PubMed/NCBI

86 

Aharinejad S, Paulus P, Sioud M, Hofmann M, Zins K, Schäfer R, Stanley ER and Abraham D: Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice. Cancer Res. 64:5378–5384. 2004. View Article : Google Scholar : PubMed/NCBI

87 

Ries CH, Cannarile MA, Hoves S, Benz J, Wartha K, Runza V, Rey-Giraud F, Pradel LP, Feuerhake F, Klaman I, et al: Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell. 25:846–859. 2014. View Article : Google Scholar : PubMed/NCBI

88 

Mantovani A and Sica A: Macrophages, innate immunity and cancer: Balance, tolerance, and diversity. Curr Opin Immunol. 22:231–237. 2010. View Article : Google Scholar : PubMed/NCBI

89 

Swierczak A, Cook AD, Lenzo JC, Restall CM, Doherty JP, Anderson RL and Hamilton JA: The promotion of breast cancer metastasis caused by inhibition of CSF-1R/CSF-1 signaling is blocked by targeting the G-CSF receptor. Cancer Immunol Res. 2:765–776. 2014. View Article : Google Scholar : PubMed/NCBI

90 

Huang J, Simpson JF, Glackin C, Riethorf L, Wagener C and Shively JE: Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells. Anticancer Res. 18((5A)): 3203–3212. 1998.PubMed/NCBI

91 

Meixner A, Zenz R, Schonthaler HB, Kenner L, Scheuch H, Penninger JM and Wagner EF: Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation. Nat Cell Biol. 10:1003–1011. 2008. View Article : Google Scholar : PubMed/NCBI

92 

Kim JS, Son Y, Bae MJ, Lee M, Lee CG, Jo WS, Kim SD and Yang K: Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice. Oncol Rep. 34:147–154. 2015. View Article : Google Scholar : PubMed/NCBI

93 

Alshamrani MA, Al-Foheidi M and Abdulrahim AH: Granulocyte Colony Stimulating Factor (G-CSF) Induced splenic infarction in breast cancer patient treated with dose-dense chemotherapy regimen. Case Rep Oncol Med. 2019:81749862019.PubMed/NCBI

94 

Kinjo Y, Kurita T, Ueda T, Kagami S, Matsuura Y and Yoshino K: Acute arteritis after G-CSF administration. Int Cancer Conf J. 8:77–80. 2019. View Article : Google Scholar : PubMed/NCBI

95 

Lu X, Wu Y, Wang H and Xia L: G-CSF-induced severe thrombocytopenia in a healthy donor: A rare case report. Medicine (Baltimore). 98:e147862019. View Article : Google Scholar : PubMed/NCBI

96 

Kim YG, Kim SR, Hwang SH, Jung JY, Kim HA and Suh CH: Mesenteric vasculitis after G-CSF administration in a severe neutropenic patient with systemic lupus erythematosus. Lupus. 25:1381–1384. 2016. View Article : Google Scholar : PubMed/NCBI

97 

Li W, Zhang X, Chen Y, Xie Y, Liu J, Feng Q, Wang Y, Yuan W and Ma J: G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers. Protein Cell. 7:130–140. 2016. View Article : Google Scholar : PubMed/NCBI

98 

Kumar J, Fraser FW, Riley C, Ahmed N, McCulloch DR and Ward AC: Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer. Br J Cancer. 110:133–145. 2014. View Article : Google Scholar : PubMed/NCBI

99 

Agarwal S, Lakoma A, Chen Z, Hicks J, Metelitsa LS, Kim ES and Shohet JM: G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation. Cancer Res. 75:2566–2579. 2015. View Article : Google Scholar : PubMed/NCBI

100 

Nakata H, Uemura Y, Kobayashi M, Harada R and Taguchi H: Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells. Cancer Sci. 94:173–180. 2003. View Article : Google Scholar : PubMed/NCBI

101 

Cui YH, Suh Y, Lee HJ, Yoo KC, Uddin N, Jeong YJ, Lee JS, Hwang SG, Nam SY, Kim MJ, et al: Radiation promotes invasiveness of non-small-cell lung cancer cells through granulocyte-colony-stimulating factor. Oncogene. 34:5372–5382. 2015. View Article : Google Scholar : PubMed/NCBI

102 

Ramakrishna C and Cantin EM: IFNγ inhibits G-CSF induced neutrophil expansion and invasion of the CNS to prevent viral encephalitis. PLoS Pathog. 14:e10068222018. View Article : Google Scholar : PubMed/NCBI

103 

Chang SF, Li HC, Huang YP, Tasi WJ, Chou YY and Lu SC: SB203580 increases G-CSF production via a stem-loop destabilizing element in the 3′ untranslated region in macrophages independently of its effect on p38 MAPK activity. J Biomed Sci. 23:32016. View Article : Google Scholar : PubMed/NCBI

104 

Fujimoto A, Akifusa S, Hirofuji T and Yamashita Y: Involvement of suppressor of cytokine signaling-1 in globular adiponectin-induced granulocyte colony-stimulating factor in RAW 264 cell. Mol Immunol. 48:2052–2058. 2011. View Article : Google Scholar : PubMed/NCBI

105 

Kamio N, Akifusa S, Yamaguchi N and Yamashita Y: Induction of granulocyte colony-stimulating factor by globular adiponectin via the MEK-ERK pathway. Mol Cell Endocrinol. 292:20–25. 2008. View Article : Google Scholar : PubMed/NCBI

106 

Zhang L, Yang M, Wang Q, Liu M, Liang Q, Zhang H and Xiao X: HSF1 regulates expression of G-CSF through the binding element for NF-IL6/CCAAT enhancer binding protein beta. Mol Cell Biochem. 352:11–17. 2011. View Article : Google Scholar : PubMed/NCBI

107 

Aoki Y, Hirano D, Kodama H, Nishi Y and Nakamura M: Stimulation of G-CSF gene expression in the macrophage cell line by contact with extracellular matrix proteins and a pre-B leukaemia cell line. Cytokine. 10:596–602. 1998. View Article : Google Scholar : PubMed/NCBI

108 

Chou YY and Lu SC: Inhibition by rapamycin of the lipoteichoic acid-induced granulocyte-colony stimulating factor expression in mouse macrophages. Arch Biochem Biophys. 508:110–119. 2011. View Article : Google Scholar : PubMed/NCBI

109 

Sallerfors B and Olofsson T: Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by adherent monocytes measured by quantitative immunoassays. Eur J Haematol. 49:199–207. 1992. View Article : Google Scholar : PubMed/NCBI

110 

Tajuddin T, Ryan EJ, Norris S, Hegarty JE and O'Farrelly C: Interferon-α suppressed granulocyte colony stimulating factor production is reversed by CL097, a TLR7/8 agonist. J Gastroenterol Hepatol. 25:1883–1890. 2010. View Article : Google Scholar : PubMed/NCBI

111 

Ichinose Y, Hara N, Ohta M, Aso H, Chikama H, Kawasaki M, Kubota I, Shimizu T and Yagawa K: Recombinant granulocyte colony-stimulating factor and lipopolysaccharide maintain the phenotype of and superoxide anion generation by neutrophils. Infect Immun. 58:1647–1652. 1990. View Article : Google Scholar : PubMed/NCBI

112 

Lindemann A, Riedel D, Oster W, Ziegler-Heitbrock HW, Mertelsmann R and Herrmann F: Granulocyte-macrophage colony-stimulating factor induces cytokine secretion by human polymorphonuclear leukocytes. J Clin Invest. 83:1308–1312. 1989. View Article : Google Scholar : PubMed/NCBI

113 

Lu L, Srour EF, Warren DJ, Walker D, Graham CD, Walker EB, Jansen J and Broxmeyer HE: Enhancement of release of granulocyte- and granulocyte-macrophage colony-stimulating factors from phytohemagglutinin-stimulated sorted subsets of human T lymphocytes by recombinant human tumor necrosis factor-alpha. Synergism with recombinant human IFN-gamma. J Immunol. 141:201–207. 1988.PubMed/NCBI

114 

Lennard Richard ML, Brandon D, Lou N, Sato S, Caldwell T, Nowling TK, Gilkeson G and Zhang XK: Acetylation impacts Fli-1-driven regulation of granulocyte colony stimulating factor. Eur J Immunol. 46:2322–2332. 2016. View Article : Google Scholar : PubMed/NCBI

115 

Rajavashisth TB, Andalibi A, Territo MC, Berliner JA, Navab M, Fogelman AM and Lusis AJ: Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins. Nature. 344:254–257. 1990. View Article : Google Scholar : PubMed/NCBI

116 

Seelentag WK, Mermod JJ, Montesano R and Vassalli P: Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells. EMBO J. 6:2261–2265. 1987. View Article : Google Scholar : PubMed/NCBI

117 

Saba S, Soong G, Greenberg S and Prince A: Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways. Am J Respir Cell Mol Biol. 27:561–567. 2002. View Article : Google Scholar : PubMed/NCBI

118 

Suzukawa M, Koketsu R, Baba S, Igarashi S, Nagase H, Yamaguchi M, Matsutani N, Kawamura M, Shoji S, Hebisawa A, et al: Leptin enhances ICAM-1 expression, induces migration and cytokine synthesis, and prolongs survival of human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 309:L801–L811. 2015. View Article : Google Scholar : PubMed/NCBI

119 

Numasaki M, Takahashi H, Tomioka Y and Sasaki H: Regulatory roles of IL-17 and IL-17F in G-CSF production by lung microvascular endothelial cells stimulated with IL-1beta and/or TNF-alpha. Immunol Lett. 95:97–104. 2004. View Article : Google Scholar : PubMed/NCBI

120 

Witowski J, Ksiazek K, Warnecke C, Kuźlan M, Korybalska K, Tayama H, Wiśniewska-Elnur J, Pawlaczyk K, Trómińska J, Breborowicz A, et al: Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum. Kidney Int. 71:514–525. 2007. View Article : Google Scholar : PubMed/NCBI

121 

Demetri GD, Zenzie BW, Rheinwald JG and Griffin JD: Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Blood. 74:940–946. 1989. View Article : Google Scholar : PubMed/NCBI

122 

Carr MJ, Li Y, Rezakhanlou AM and Ghahary A: Keratinocyte-releasable factors stimulate the expression of granulocyte colony-stimulating factor in human dermal fibroblasts. J Cell Biochem. 118:308–317. 2017. View Article : Google Scholar : PubMed/NCBI

123 

Ramachandran R, Morice AH and Compton SJ: Proteinase-activated receptor2 agonists upregulate granulocyte colony-stimulating factor, IL-8, and VCAM-1 expression in human bronchial fibroblasts. Am J Respir Cell Mol Biol. 35:133–141. 2006. View Article : Google Scholar : PubMed/NCBI

124 

Koeffler HP, Gasson J, Ranyard J, Souza L, Shepard M and Munker R: Recombinant human TNF alpha stimulates production of granulocyte colony-stimulating factor. Blood. 70:55–59. 1987. View Article : Google Scholar : PubMed/NCBI

125 

Seelentag W, Mermod JJ and Vassalli P: Interleukin 1 and tumor necrosis factor-alpha additively increase the levels of granulocyte-macrophage and granulocyte colony-stimulating factor (CSF) mRNA in human fibroblasts. Eur J Immunol. 19:209–212. 1989. View Article : Google Scholar : PubMed/NCBI

126 

Zgheib A, Lamy S and Annabi B: Epigallocatechin gallate targeting of membrane type 1 matrix metalloproteinase-mediated Src and Janus kinase/signal transducers and activators of transcription 3 signaling inhibits transcription of colony-stimulating factors 2 and 3 in mesenchymal stromal cells. J Biol Chem. 288:13378–13386. 2013. View Article : Google Scholar : PubMed/NCBI

127 

Fibbe WE, van Damme J, Billiau A, Goselink HM, Voogt PJ, van Eeden G, Ralph P, Altrock BW and Falkenburg JH: Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony-stimulating factor. Blood. 71:430–435. 1988. View Article : Google Scholar : PubMed/NCBI

128 

Tesio M, Oser GM, Baccelli I, Blanco-Bose W, Wu H, Göthert JR, Kogan SC and Trumpp A: Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization. J Exp Med. 210:2337–2349. 2013. View Article : Google Scholar : PubMed/NCBI

129 

Grace MB, Singh VK, Rhee JG, Jackson WE III, Kao TC and Whitnall MH: 5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosis. J Radiat Res (Tokyo). 53:840–853. 2012. View Article : Google Scholar

130 

Kimura A, Kinjyo I, Matsumura Y, Mori H, Mashima R, Harada M, Chien KR, Yasukawa H and Yoshimura A: SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling. J Biol Chem. 279:6905–6910. 2004. View Article : Google Scholar : PubMed/NCBI

131 

Smith A, Witte E, McGee D, Knott J, Narang K and Racicot K: Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits invasion in first-trimester trophoblast cells. Am J Reprod Immunol. 78:e127412017. View Article : Google Scholar

132 

Ordelheide AM, Gommer N, Böhm A, Hermann C, Thielker I, Machicao F, Fritsche A, Stefan N, Häring HU and Staiger H: Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans. Mol Metab. 5:305–316. 2016. View Article : Google Scholar : PubMed/NCBI

133 

Hudock KM, Liu Y, Mei J, Marino RC, Hale JE, Dai N and Worthen GS: Delayed resolution of lung inflammation in Il-1rn-/- mice reflects elevated IL-17A/granulocyte colony-stimulating factor expression. Am J Respir Cell Mol Biol. 47:436–444. 2012. View Article : Google Scholar : PubMed/NCBI

134 

Soria-Castro I, Krzyzanowska A, Pelaéz ML, Regadera J, Ferrer G, Montoliu L, Rodríguez-Ramos R, Fernández M and Alemany S: Cot/tpl2 (MAP3K8) mediates myeloperoxidase activity and hypernociception following peripheral inflammation. J Biol Chem. 285:33805–33815. 2010. View Article : Google Scholar : PubMed/NCBI

135 

Janelle MF, Doucet A, Bouchard D, Bourbonnais Y and Tremblay GM: Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema. Biol Chem. 387:903–909. 2006. View Article : Google Scholar : PubMed/NCBI

136 

Bohannon JK, Luan L, Hernandez A, Afzal A, Guo Y, Patil NK, Fensterheim B and Sherwood ER: Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. J Leukoc Biol. 99:629–640. 2016. View Article : Google Scholar : PubMed/NCBI

137 

Ellis GS, Carlson DE, Hester L, He JR, Bagby GJ, Singh IS and Hasday JD: G-CSF, but not corticosterone, mediates circulating neutrophilia induced by febrile-range hyperthermia. J Appl Physiol. 98:1799–1804. 2005. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Liu L, Liu Y, Yan X, Zhou C and Xiong X: The role of granulocyte colony‑stimulating factor in breast cancer development: A review. Mol Med Rep 21: 2019-2029, 2020.
APA
Liu, L., Liu, Y., Yan, X., Zhou, C., & Xiong, X. (2020). The role of granulocyte colony‑stimulating factor in breast cancer development: A review. Molecular Medicine Reports, 21, 2019-2029. https://doi.org/10.3892/mmr.2020.11017
MLA
Liu, L., Liu, Y., Yan, X., Zhou, C., Xiong, X."The role of granulocyte colony‑stimulating factor in breast cancer development: A review". Molecular Medicine Reports 21.5 (2020): 2019-2029.
Chicago
Liu, L., Liu, Y., Yan, X., Zhou, C., Xiong, X."The role of granulocyte colony‑stimulating factor in breast cancer development: A review". Molecular Medicine Reports 21, no. 5 (2020): 2019-2029. https://doi.org/10.3892/mmr.2020.11017
Copy and paste a formatted citation
x
Spandidos Publications style
Liu L, Liu Y, Yan X, Zhou C and Xiong X: The role of granulocyte colony‑stimulating factor in breast cancer development: A review. Mol Med Rep 21: 2019-2029, 2020.
APA
Liu, L., Liu, Y., Yan, X., Zhou, C., & Xiong, X. (2020). The role of granulocyte colony‑stimulating factor in breast cancer development: A review. Molecular Medicine Reports, 21, 2019-2029. https://doi.org/10.3892/mmr.2020.11017
MLA
Liu, L., Liu, Y., Yan, X., Zhou, C., Xiong, X."The role of granulocyte colony‑stimulating factor in breast cancer development: A review". Molecular Medicine Reports 21.5 (2020): 2019-2029.
Chicago
Liu, L., Liu, Y., Yan, X., Zhou, C., Xiong, X."The role of granulocyte colony‑stimulating factor in breast cancer development: A review". Molecular Medicine Reports 21, no. 5 (2020): 2019-2029. https://doi.org/10.3892/mmr.2020.11017
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team