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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2020 Volume 21 Issue 5

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances of the experimental models of idiopathic membranous nephropathy (Review)

Han Xue Jiang, Zhendong Feng, Ze Bing Zhu, Chen Hui Xia, Wenting Zhang, Jing Guo, Bao‑Li Liu, Yaoxian Wang, Yu Ning Liu, Wei Jing Liu
Pages: 1993-2005
Published online on: 09 March 2020

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Modulators of microglia activation and polarization in ischemic stroke (Review)

Cheng‑Ting Jiang, Wan‑Feng Wu, Yi‑Hui Deng, Jin‑Wen Ge
Pages: 2006-2018
Published online on: 26 February 2020

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Article Open Access

The role of granulocyte colony‑stimulating factor in breast cancer development: A review

Li Liu, Yangyang Liu, Xiaohua Yan, Chong Zhou, Xiangyang Xiong
Pages: 2019-2029
Published online on: 10 March 2020

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Article Open Access

Anti‑inflammatory role of Prunus persica L. Batsch methanol extract on lipopolysaccharide‑stimulated glial cells

Kyoung Hee Seo, So Young Choi, Yeonsun Jin, Heebin Son, Young Sun Kang, Seung Hyo Jung, Yong‑In Kim, Sangmi Eum, Tran The Bach, Hee Min Yoo, Wan Kyunn Whang, Sun‑Young Jung, Wonku Kang, Hyun Myung Ko, Sung Hoon Lee
Pages: 2030-2040
Published online on: 10 March 2020

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Mechanisms of impaired pancreatic β‑cell function in high‑fat diet‑induced obese mice: The role of endoplasmic reticulum stress

Xiaoqing Yi, Xuan Cai, Sisi Wang, Yanfeng Xiao
Pages: 2041-2050
Published online on: 05 March 2020

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Article Open Access

Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics

Bo Wang, Lingxia Wang, Jiahui Mao, Huiyan Wen, Longjiang Xu, Yang Ren, Hong Du, Huan Yang
Pages: 2051-2062
Published online on: 12 March 2020

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Pilot study and bioinformatics analysis of differentially expressed genes in adipose tissues of rats with excess dietary intake

Jun Chao Yuan, Thaneswary Yogarajah, Shern Kwok Lim, Get Bee Yvonne Tee, Boon Yin Khoo
Pages: 2063-2072
Published online on: 04 March 2020

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MicroRNA‑200a promotes esophageal squamous cell carcinoma cell proliferation, migration and invasion through extensive target genes

Bian Yang, Yumeng Liu, Lipeng Li, Hailong Deng, Lei Xian
Pages: 2073-2084
Published online on: 26 February 2020

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Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway

Jiakan Yuan, Xuxia Wang, Dan Ma, Hui Gao, Dehua Zheng, Jun Zhang
Pages: 2085-2094
Published online on: 11 March 2020

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β‑asarone modulates Beclin‑1, LC3 and p62 expression to attenuate Aβ40 and Aβ42 levels in APP/PS1 transgenic mice with Alzheimer's disease

Minzhen Deng, Liping Huang, Xiaoqin Zhong
Pages: 2095-2102
Published online on: 13 March 2020

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Angiotensin II induces RAW264.7 macrophage polarization to the M1‑type through the connexin 43/NF‑κB pathway

Lei Wu, Kai Chen, Jingjie Xiao, Junzhou Xin, Liang Zhang, Xinzhi Li, Li Li, Junqiang Si, Li Wang, Ketao Ma
Pages: 2103-2112
Published online on: 12 March 2020

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Article Open Access

The roles of mechanosensitive ion channels and associated downstream MAPK signaling pathways in PDLC mechanotransduction

Yun Shen, Yongchu Pan, Shuyu Guo, Lian Sun, Chi Zhang, Lin Wang
Pages: 2113-2122
Published online on: 27 February 2020

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Regulatory effect of rat bone marrow mesenchymal stem cells on Treg/Th17 immune balance in vitro

Kai Wang, Yan‑Jun Shi, Zhuo‑Lun Song, Bin Wu, Chun‑Lei Zhou, Wei Liu, Wei Gao
Pages: 2123-2130
Published online on: 11 March 2020

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Article Open Access

lncRNA CASC2 downregulation participates in rheumatoid arthritis, and CASC2 overexpression promotes the apoptosis of fibroblast‑like synoviocytes by downregulating IL‑17

Cheng Liu, Xiaojun Guo, Sunpeng Bai, Guangjun Zeng, Hao Wang
Pages: 2131-2137
Published online on: 10 March 2020

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Integrated analysis of DNA methylation and transcriptome profiling of polycystic ovary syndrome

Li Liu, Dongyun He, Yang Wang, Minjia Sheng
Pages: 2138-2150
Published online on: 26 February 2020

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Article Open Access

miR‑296‑3p promotes the proliferation of glioblastoma cells by targeting ICAT

Jing Zhou, Guobo Du, Hongmei Fu
Pages: 2151-2161
Published online on: 03 March 2020

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Article Open Access

Pirfenidone ameliorates the formation of choroidal neovascularization in mice

Yueqi Bao, Lili Huang, Xiaobo Huang, Chuang Gao, Yu Chen, Liucheng Wu, Shunxing Zhu, Yu Song
Pages: 2162-2170
Published online on: 27 February 2020

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Necrostatin‑1 protects mice from acute lung injury by suppressing necroptosis and reactive oxygen species

Bi Lin, Ziyuan Jin, Xiang Chen, Li Zhao, Chengwei Weng, Baihui Chen, Yaning Tang, Lina Lin
Pages: 2171-2181
Published online on: 03 March 2020

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Prevention of renal ischemia and reperfusion injury by penehyclidine hydrochloride through autophagy activation

Yuqing Kang, Yuebing Li, Heng Wen, Junfeng Zhu, Jiangbo Zheng, Zhaoming Feng
Pages: 2182-2192
Published online on: 12 March 2020

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ATG7 promotes autophagy in sepsis‑induced acute kidney injury and is inhibited by miR‑526b

Ying Liu, Jilai Xiao, Jiakui Sun, Wenxiu Chen, Shu Wang, Run Fu, Han Liu, Hongguang Bao
Pages: 2193-2201
Published online on: 26 February 2020

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Wnt/β‑catenin signaling modulates piperine‑mediated antitumor effects on human osteosarcoma cells

Yu‑Bin Qi, Wen Yang, Meng Si, Lin Nie
Pages: 2202-2208
Published online on: 26 February 2020

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PDGFD induces ibrutinib resistance of diffuse large B‑cell lymphoma through activation of EGFR

Jia Jin, Leiping Wang, Zhonghua Tao, Jian Zhang, Fangfang Lv, Junning Cao, Xichun Hu
Pages: 2209-2219
Published online on: 12 March 2020

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Long non‑coding RNA MALAT1 promotes high glucose‑induced rat cartilage endplate cell apoptosis via the p38/MAPK signalling pathway

Zengxin Jiang, Qingmin Zeng, Defang Li, Lei Ding, Wei Lu, Mengxuan Bian, Jingping Wu
Pages: 2220-2226
Published online on: 03 March 2020

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Non‑invasive proteome‑wide quantification of skin barrier‑related proteins using label‑free LC‑MS/MS analysis

Mengting Liu, Jing Zhang, Yaochi Wang, Cong Xin, Jie Ma, Shuangjun Xu, Xiaomeng Wang, Jinping Gao, Xuejun Zhang, Sen Yang
Pages: 2227-2235
Published online on: 11 March 2020

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Article

Deletion of p21 expression accelerates cartilage tissue repair via chondrocyte proliferation

Kazuyuki Ibaraki, Shinya Hayashi, Noriyuki Kanzaki, Shingo Hashimoto, Shinsuke Kihara, Masahiko Haneda, Kazuhiro Takeuchi, Takahiro Niikura, Ryosuke Kuroda
Pages: 2236-2242
Published online on: 13 March 2020

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Article

Anti‑inflammatory and anti‑catabolic effect of non‑animal stabilized hyaluronic acid and mesenchymal stem cell‑conditioned medium in an osteoarthritis coculture model

Mario Simental‑Mendía, Sonia Amelia Lozano‑Sepúlveda, Vanessa Pérez‑Silos, Lizeth Fuentes‑Mera, Herminia Guadalupe Martínez‑Rodríguez, Carlos Alberto Acosta‑Olivo, Víctor Manuel Peña‑Martínez, Félix Vilchez‑Cavazos
Pages: 2243-2250
Published online on: 26 February 2020

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7‑Difluoromethyl‑5,4'‑dimethoxygenistein exerts anti‑angiogenic effects on acute promyelocytic leukemia HL‑60 cells by inhibiting the TLR4/NF‑κB signaling pathway

Xueping Xiang, Lesai Li, Pingjuan Bo, Ting Kuang, Sujuan Liu, Xiaolin Xie, Sihui Guo, Xiaohua Fu, Yong Zhang
Pages: 2251-2259
Published online on: 18 March 2020

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Article

MicroRNA‑196b targets COSMC in pediatric IgA nephropathy

Qiang Sun, Jingchao Lan, Hong Zhang, Nan Zhou, Ying Liang, Xiaorong Liu
Pages: 2260-2266
Published online on: 09 March 2020

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Article

Rat bone mesenchymal stem cells exert antiproliferative effects on nicotine‑exposed T cells via iNOS production

Xiaoyan Li, Jianying Xu, Pingping Li
Pages: 2267-2275
Published online on: 13 March 2020

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Article

MicroRNA-744 promotes proliferation of osteosarcoma cells by targeting PTEN

Wei Yu, Peng-Bo Chen, Fan-Cheng Chen, Sheng-Long Ding, Xiao-Yun Pan
Pages: 2276-2282
Published online on: 18 March 2020

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Correction Open Access

[Corrigendum] Cortex Mori Radicis Extract promotes neurite outgrowth of diabetic rats by activating PI3K/AKT signaling and inhibiting Ca2+ influx associated with upregulation of transient receptor potential canonical channel 1

Min Lu, Tao Yi, Yong Xiong, Qian Wang, Nina Yin
Pages: 2283-2283
Published online on: 28 February 2020

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Correction Open Access

[Corrigendum] Involvement of endothelial nitric oxide synthase pathway in IGF‑1 protects endothelial progenitor cells against injury from oxidized LDLs

Jing‑Wen Hao, Guo‑Feng Liu, Li‑Zhi Xiao, Yong‑Gang Wu
Pages: 2284-2284
Published online on: 18 March 2020

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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