|
1
|
GBD 2015 Disease, Injury Incidence and
Prevalence Collaborators: Global, regional, and national incidence,
prevalence, and years lived with disability for 310 diseases and
injuries, 1990–2015: A systematic analysis for the global burden of
disease study 2015. Lancet. 388:1545–1602. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
GBD 2015 Mortality and Causes of Death
Collaborators, . Global, regional, and national life expectancy,
all-cause mortality, and cause-specific mortality for 249 causes of
death, 1980–2015: A systematic analysis for the global burden of
disease study 2015. Lancet. 388:1459–1544. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Decramer M, Janssens W and Miravitlles M:
Chronic obstructive pulmonary disease. Lancet. 379:1341–1351. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Salvi S: Tobacco smoking and environmental
risk factors for chronic obstructive pulmonary disease. Clin Chest
Med. 35:17–27. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Strzelak A, Ratajczak A, Adamiec A and
Feleszko W: Tobacco smoke induces and alters immune responses in
the lung triggering inflammation, allergy, asthma and other lung
diseases: A mechanistic review. Int J Environ Res Public Health.
15(pii): E10332018. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Qiu F, Liang CL, Liu H, Zeng YQ, Hou S,
Huang S, Lai X and Dai Z: Impacts of cigarette smoking on immune
responsiveness: Up and down or upside down? Oncotarget. 8:268–284.
2017.PubMed/NCBI
|
|
7
|
Gadgil A and Duncan SR: Role of
T-lymphocytes and pro-inflammatory mediators in the pathogenesis of
chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon
Dis. 3:531–541. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Nurwidya F, Damayanti T and Yunus F: The
role of innate and adaptive immune cells in the immunopathogenesis
of chronic obstructive pulmonary disease. Tuberc Respir Dis
(Seoul). 79:5–13. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Rinaldi M, Maes K, De Vleeschauwer S,
Thomas D, Verbeken EK, Decramer M, Janssens W and Gayan-Ramirez GN:
Long-term nose-only cigarette smoke exposure induces emphysema and
mild skeletal muscle dysfunction in mice. Dis Model Mech.
5:333–341. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Sullivan AK, Simonian PL, Falta MT,
Mitchell JD, Cosgrove GP, Brown KK, Kotzin BL, Voelkel NF and
Fontenot AP: Oligoclonal CD4+ T cells in the lungs of patients with
severe emphysema. Am J Respir Crit Care Med. 172:590–596. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Hogg JC, Chu F, Utokaparch S, Woods R,
Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson
HO and Paré PD: The nature of small-airway obstruction in chronic
obstructive pulmonary disease. N Engl J Med. 350:2645–2653. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
D'Hulst AI, Vermaelen KY, Brusselle GG,
Joos GF and Pauwels RA: Time course of cigarette smoke-induced
pulmonary inflammation in mice. Eur Respir J. 26:204–213. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
D'Hulst AI, Maes T, Bracke KR, Demedts IK,
Tournoy KG, Joos GF and Brusselle GG: Cigarette smoke-induced
pulmonary emphysema in scid-mice. Is the acquired immune system
required? Respir Res. 6:1472005.PubMed/NCBI
|
|
14
|
Jiang XX, Zhang Y, Liu B, Zhang SX, Wu Y,
Yu XD and Mao N: Human mesenchymal stem cells inhibit
differentiation and function of monocyte-derived dendritic cells.
Blood. 105:4120–4126. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Corcione A, Benvenuto F, Ferretti E,
Giunti D, Cappiello V, Cazzanti F, Risso M, Gualandi F, Mancardi
GL, Pistoia V and Uccelli A: Human mesenchymal stem cells modulate
B-cell functions. Blood. 107:367–372. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Di Nicola M, Carlo-Stella C, Magni M,
Milanesi M, Longoni PD, Matteucci P, Grisanti S and Gianni AM:
Human bone marrow stromal cells suppress T-lymphocyte proliferation
induced by cellular or nonspecific mitogenic stimuli. Blood.
99:3838–3843. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Krampera M, Glennie S, Dyson J, Scott D,
Laylor R, Simpson E and Dazzi F: Bone marrow mesenchymal stem cells
inhibit the response of naive and memory antigen-specific T cells
to their cognate peptide. Blood. 101:3722–3729. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Tse WT, Pendleton JD, Beyer WM, Egalka MC
and Guinan EC: Suppression of allogeneic T-cell proliferation by
human marrow stromal cells: Implications in transplantation.
Transplantation. 75:389–397. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Rasmusson I, Ringden O, Sundberg B and Le
Blanc K: Mesenchymal stem cells inhibit lymphocyte proliferation by
mitogens and alloantigens by different mechanisms. Exp Cell Res.
305:33–41. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Sato K, Ozaki K, Oh I, Meguro A, Hatanaka
K, Nagai T, Muroi K and Ozawa K: Nitric oxide plays a critical role
in suppression of T-cell proliferation by mesenchymal stem cells.
Blood. 109:228–234. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Wang M, Yuan Q and Xie L: Mesenchymal stem
cell-based immunomodulation: Properties and clinical application.
Stem Cells Int. 2018:30576242018. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yagi H, Soto-Gutierrez A, Parekkadan B,
Kitagawa Y, Tompkins RG, Kobayashi N and Yarmush ML: Mesenchymal
stem cells: Mechanisms of immunomodulation and homing. Cell
Transplant. 19:667–679. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zinöcker S and Vaage JT: Rat mesenchymal
stromal cells inhibit T cell proliferation but not cytokine
production through inducible nitric oxide synthase. Front Immunol.
3:622012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Li X, Wang J, Cao J, Ma L and Xu J:
Immunoregulation of bone marrow-derived mesenchymal stem cells on
the chronic cigarette smoking-induced lung inflammation in rats.
Biomed Res Int. 2015:9329232015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Vig M, Srivastava S, Kandpal U, Sade H,
Lewis V, Sarin A, George A, Bal V, Durdik JM and Rath S: Inducible
nitric oxide synthase in T cells regulates T cell death and immune
memory. J Clin Invest. 113:1734–1742. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
National Research Council (US) Committee
for the Update of the Guide for the Care and Use of Laboratory
Animals, . Guide for the Care and Use of Laboratory Animals. 8th.
Washington (DC): National Academies Press (US); 2011
|
|
27
|
Mendicino M, Bailey AM, Wonnacott K, Puri
RK and Bauer SR: MSC-based product characterization for clinical
trials: An FDA perspective. Cell Stem Cell. 14:141–145. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wulfing C, Sjaastad MD and Davis MM:
Visualizing the dynamics of T cell activation: Intracellular
adhesion molecule 1 migrates rapidly to the T cell/B cell interface
and acts to sustain calcium levels. Proc Natl Acad Sci USA.
95:6302–6307. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Barnes PJ and Cosio MG: Characterization
of T lymphocytes in chronic obstructive pulmonary disease. PLoS
Med. 1:e202004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Ni L and Dong C: Roles of myeloid and
lymphoid cells in the pathogenesis of chronic obstructive pulmonary
disease. Front Immunol. 9:14312018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Antunes MA, Lapa E Silva JR and Rocco PR:
Mesenchymal stromal cell therapy in COPD: From bench to bedside.
Int J Chron Obstruct Pulmon Dis. 12:3017–3027. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Broekman W, Khedoe P, Schepers K, Roelofs
H, Stolk J and Hiemstra PS: Mesenchymal stromal cells: A novel
therapy for the treatment of chronic obstructive pulmonary disease?
Thorax. 73:565–574. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kruk DMLW, Heijink IH, Slebos DJ, Timens W
and Ten Hacken NH: Mesenchymal stromal cells to regenerate
emphysema: On the horizon? Respiration. 96:148–158. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Maitra B, Szekely E, Gjini K, Laughlin MJ,
Dennis J, Haynesworth SE and Koç ON: Human mesenchymal stem cells
support unrelated donor hematopoietic stem cells and suppress
T-cell activation. Bone Marrow Transplant. 33:597–604. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Beyth S, Borovsky Z, Mevorach D,
Liebergall M, Gazit Z, Aslan H, Galun E and Rachmilewitz J: Human
mesenchymal stem cells alter antigen-presenting cell maturation and
induce T-cell unresponsiveness. Blood. 105:2214–2219. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Groh ME, Maitra B, Szekely E and Koç ON:
Human mesenchymal stem cells require monocyte-mediated activation
to suppress alloreactive T cells. Exp Hematol. 33:928–934. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Meisel R, Zibert A, Laryea M, Gobel U,
Daubener W and Dilloo D: Human bone marrow stromal cells inhibit
allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated
tryptophan degradation. Blood. 103:4619–4621. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Glennie S, Soeiro I, Dyson PJ, Lam EW and
Dazzi F: Bone marrow mesenchymal stem cells induce division arrest
anergy of activated T cells. Blood. 105:2821–2827. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Djouad F, Plence P, Bony C, Tropel P,
Apparailly F, Sany J, Noel D and Jorgensen C: Immunosuppressive
effect of mesenchymal stem cells favors tumor growth in allogeneic
animals. Blood. 102:3837–3844. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Laing AG, Fanelli G, Ramirez-Valdez A,
Lechler RI, Lombardi G and Sharpe PT: Mesenchymal stem cells
inhibit T-cell function through conserved induction of cellular
stress. PLoS One. 14:e02131702019. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Su J, Chen X, Huang Y, Li W, Li J, Cao K,
Cao G, Zhang L, Li F, Roberts AI, et al: Phylogenetic distinction
of iNOS and IDO function in mesenchymal stem cell-mediated
immunosuppression in mammalian species. Cell Death Differ.
21:388–396. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Shi Y, Su J, Roberts AI, Shou P, Rabson AB
and Ren G: How mesenchymal stem cells interact with tissue immune
responses. Trends Immunol. 33:136–143. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Prockop DJ: ‘Stemness’ does not explain
the repair of many tissues by mesenchymal stem/multipotent stromal
cells (MSCs). Clin Pharmacol Ther. 82:241–243. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Stagg J: Immune regulation by mesenchymal
stem cells: Two sides to the coin. Tissue Antigens. 69:1–9. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Mazzoni A, Bronte V, Visintin A, Spitzer
JH, Apolloni E, Serafini P, Zanovello P and Segal DM: Myeloid
suppressor lines inhibit T cell responses by an NO-dependent
mechanism. J Immunol. 168:689–695. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Owen DL and Farrar MA: STAT5 and CD4
+ T cell immunity. F1000Res. 6:322017. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Tripathi P, Kurtulus S, Wojciechowski S,
Sholl A, Hoebe K, Morris SC, Finkelman FD, Grimes HL and Hildeman
DA: STAT5 is critical to maintain effector CD8+ T cell responses. J
Immunol. 185:2116–2124. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Maeno T, Houghton AM, Quintero PA,
Grumelli S, Owen CA and Shapiro SD: CD8+ T cells are required for
inflammation and destruction in cigarette smoke-induced emphysema
in mice. J Immunol. 178:8090–8096. 2007. View Article : Google Scholar : PubMed/NCBI
|
