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Article Open Access

Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy

Retraction in: /10.3892/mmr.2024.13294
  • Authors:
    • Yongli Hu
    • Bing Wang
    • Lie Wang
    • Zhenran Wang
    • Zhiyuan Jian
    • Lin Deng
  • View Affiliations / Copyright

    Affiliations: Department of Gastrointestinal Surgery, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi 541001, P.R. China, Department of General Surgery, 900th Hospital of the Joint Service Support Force of the PLA, Fuzhou, Fujian 350000, P.R. China
    Copyright: © Hu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 398-404
    |
    Published online on: April 28, 2020
       https://doi.org/10.3892/mmr.2020.11098
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Abstract

Mammalian STE20-like kinase 1 (MST1) plays an important role in pancreatic cancer progression, but its downstream targets are still unknown. In the present study, our results indicated that MST1 expression was significantly downregulated in pancreatic cancer cell lines (PANC‑1, BxPC‑3 and HPAC) compared with that in the normal ductal epithelial cell line (hTERT‑HPNE). Moreover, MST1 overexpression in PANC‑1 cells led to increased apoptosis as determined by MTT and TUNEL assays and inhibited cellular migration. Mechanistically, upregulation of MST1 expression caused mitochondrial dysfunction, decreased ATP production, and activation of the mitochondrial‑dependent apoptotic pathway via inhibition of mitofusin 2 (Mfn2)‑mediated mitophagy, which ultimately resulted in increased cellular apoptosis and decreased cellular migration. Collectively, the present study demonstrated that MST1 may regulate pancreatic cancer PANC‑1 cell survival, invasion and migration through Mfn2‑mediated mitophagy, laying the foundation for the exploration of novel therapeutic targets for pancreatic cancer.
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View References

1 

Ilic M and Ilic I: Epidemiology of pancreatic cancer. World J Gastroenterol. 22:9694–9705. 2016. View Article : Google Scholar : PubMed/NCBI

2 

Lin QJ, Yang F, Jin C and Fu DL: Current status and progress of pancreatic cancer in China. World J Gastroenterol. 21:7988–8003. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Ercan G, Karlitepe A and Ozpolat B: Pancreatic cancer stem cells and therapeutic approaches. Anticancer Res. 37:2761–2775. 2017.PubMed/NCBI

4 

Grasso C, Jansen G and Giovannetti E: Drug resistance in pancreatic cancer: Impact of altered energy metabolism. Crit Rev Oncol Hematol. 114:139–152. 2017. View Article : Google Scholar : PubMed/NCBI

5 

Zhou B, Xu JW, Cheng YG, Gao JY, Hu SY, Wang L and Zhan HX: Early detection of pancreatic cancer: Where are we now and where are we going? Int J Cancer. 141:231–241. 2017. View Article : Google Scholar : PubMed/NCBI

6 

Luo XM, Niu LZ, Chen JB and Xu KC: Advances in cryoablation for pancreatic cancer. World J Gastroenterol. 22:790–800. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Ansari D, Tingstedt B, Andersson B, Holmquist F, Sturesson C, Williamsson C, Sasor A, Borg D, Bauden M and Andersson R: Pancreatic cancer: Yesterday, today and tomorrow. Future Oncol. 12:1929–1946. 2016. View Article : Google Scholar : PubMed/NCBI

8 

Li C, Bi Y, Li Y, Yang H, Yu Q, Wang J, Wang Y, Su H, Jia A, Hu Y, et al: Dendritic cell MST1 inhibits Th17 differentiation. Nat Commun. 8:142752017. View Article : Google Scholar : PubMed/NCBI

9 

Zhang M, Lin J, Wang S, Cheng Z, Hu J, Wang T, Man W, Yin T, Guo W, Gao E, et al: Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling. J Pineal Res. 63:284805972017. View Article : Google Scholar

10 

Zhang M, Zhang L, Hu J, Lin J, Wang T, Duan Y, Man W, Feng J, Sun L, Jia H, et al: MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice. Diabetologia. 59:2435–2447. 2016. View Article : Google Scholar : PubMed/NCBI

11 

Li Q, Qi F, Meng X, Zhu C and Gao Y: Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway. Cell Biol Toxicol. 34:263–277. 2018. View Article : Google Scholar : PubMed/NCBI

12 

Yang Y, Wang H, Ma Z, Hu W and Sun D: Understanding the role of mammalian sterile 20-like kinase 1 (MST1) in cardiovascular disorders. J Mol Cell Cardiol. 114:141–149. 2018. View Article : Google Scholar : PubMed/NCBI

13 

Wang X and Song Q: Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway. Cell Mol Biol Lett. 23:212018. View Article : Google Scholar : PubMed/NCBI

14 

Meng Z, Moroishi T, Mottier-Pavie V, Plouffe SW, Hansen CG, Hong AW, Park HW, Mo JS, Lu W, Lu S, et al: MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 6:83572015. View Article : Google Scholar : PubMed/NCBI

15 

Chen M, Zhang H, Shi Z, Li Y, Zhang X, Gao Z, Zhou L, Ma J, Xu Q, Guan J, et al: The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer. J Biol Chem. 293:14455–14469. 2018. View Article : Google Scholar : PubMed/NCBI

16 

Li JA, Kuang T, Pu N, Fang Y, Han X, Zhang L, Xu X, Wu W, Wang D, Lou W, et al: TRAF6 regulates YAP signaling by promoting the ubiquitination and degradation of MST1 in pancreatic cancer. Clin Exp Med. 19:211–218. 2019. View Article : Google Scholar : PubMed/NCBI

17 

Li X, Liu Y, Zhang C, Niu Q, Wang H, Che C, Xie M, Zhou B, Xu Y, Zhang Q, et al: Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway. Oncotarget. 8:16356–16366. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Zhan L, Li J and Wei B: Autophagy in endometriosis: Friend or foe? Biochem Biophys Res Commun. 495:60–63. 2018. View Article : Google Scholar : PubMed/NCBI

19 

McEwan DG: Host-pathogen interactions and subversion of autophagy. Essays Biochem. 61:687–697. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Benischke AS, Vasanth S, Miyai T, Katikireddy KR, White T, Chen Y, Halilovic A, Price M, Price F Jr, Liton PB, et al: Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy. Sci Rep. 7:66562017. View Article : Google Scholar : PubMed/NCBI

21 

Sebastián D, Sorianello E, Segalés J, Irazoki A, Ruiz-Bonilla V, Sala D, Planet E, Berenguer-Llergo A, Muñoz JP, Sánchez-Feutrie M, et al: Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway. EMBO J. 35:1677–1693. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Zhang Z and Yu J: NR4A1 Promotes cerebral ischemia reperfusion injury by repressing mfn2-mediated mitophagy and inactivating the MAPK-ERK-CREB signaling pathway. Neurochem Res. 43:1963–1977. 2018. View Article : Google Scholar : PubMed/NCBI

23 

Yan H, Qiu C, Sun W, Gu M, Xiao F, Zou J and Zhang L: Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy. Oncol Rep. 39:1671–1681. 2018.PubMed/NCBI

24 

Kulikov AV, Luchkina EA, Gogvadze V and Zhivotovsky B: Mitophagy: Link to cancer development and therapy. Biochem Biophys Res Commun. 482:432–439. 2017. View Article : Google Scholar : PubMed/NCBI

25 

Wang S, Zhao Z, Feng X, Cheng Z, Xiong Z, Wang T, Lin J, Zhang M, Hu J, Fan Y, et al: Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition. J Cell Mol Med. 22:5132–5144. 2018. View Article : Google Scholar : PubMed/NCBI

26 

Yu W, Xu M, Zhang T, Zhang Q and Zou C: Mst1 promotes cardiac ischemia-reperfusion injury by inhibiting the ERK-CREB pathway and repressing FUNDC1-mediated mitophagy. J Physiol Sci. 69:113–127. 2019. View Article : Google Scholar : PubMed/NCBI

27 

Chen SH, Hung WC, Wang P, Paul C and Konstantopoulos K: Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation. Sci Rep. 3:18702013. View Article : Google Scholar : PubMed/NCBI

28 

Zhu P, Hu S, Jin Q, Li D, Tian F, Toan S, Li Y, Zhou H and Chen Y: Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway. Redox Biol. 16:157–168. 2018. View Article : Google Scholar : PubMed/NCBI

29 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

30 

Liu H, Mei D, Xu P, Wang H and Wang Y: YAP promotes gastric cancer cell survival and migration/invasion via the ERK/endoplasmic reticulum stress pathway. Oncol Lett. 18:6752–6758. 2019.PubMed/NCBI

31 

Gao X, Zhang X, Hu J, Xu X, Zuo Y, Wang Y, Ding J, Xu H and Zhu S: Aconitine induces apoptosis in H9c2 cardiac cells via mitochondria-mediated pathway. Mol Med Rep. 17:284–292. 2018.PubMed/NCBI

32 

Mody HR, Hung SW, Pathak RK, Griffin J, Cruz-Monserrate Z and Govindarajan R: miR-202 diminishes TGFβ receptors and attenuates TGFβ1-induced EMT in pancreatic cancer. Mol Cancer Res. 15:1029–1039. 2017. View Article : Google Scholar : PubMed/NCBI

33 

Zhou P, Li B, Liu F, Zhang M, Wang Q, Liu Y, Yao Y and Li D: The epithelial to mesenchymal transition (EMT) and cancer stem cells: Implication for treatment resistance in pancreatic cancer. Mol Cancer. 16:522017. View Article : Google Scholar : PubMed/NCBI

34 

Zhao H, Duan Q, Zhang Z, Li H, Wu H, Shen Q, Wang C and Yin T: Up-regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine-resistant pancreatic cancer cells. J Cell Mol Med. 21:2055–2067. 2017. View Article : Google Scholar : PubMed/NCBI

35 

Kane MS, Paris A, Codron P, Cassereau J, Procaccio V, Lenaers G, Reynier P and Chevrollier A: Current mechanistic insights into the CCCP-induced cell survival response. Biochem Pharmacol. 148:100–110. 2018. View Article : Google Scholar : PubMed/NCBI

36 

Cui J, Zhou Z, Yang H, Jiao F, Li N, Gao Y, Wang L, Chen J and Quan M: MST1 suppresses pancreatic cancer progression via ROS-induced pyroptosis. Mol Cancer Res. 17:1316–1325. 2019. View Article : Google Scholar : PubMed/NCBI

37 

Bernardini JP, Lazarou M and Dewson G: Parkin and mitophagy in cancer. Oncogene. 36:1315–1327. 2017. View Article : Google Scholar : PubMed/NCBI

38 

Chang SH, Lee AY, Yu KN, Park J, Kim KP and Cho MH: Dihydroergotamine tartrate induces lung cancer cell death through apoptosis and mitophagy. Chemotherapy. 61:304–312. 2016. View Article : Google Scholar : PubMed/NCBI

39 

Chang M and Song X, Geng X, Wang X, Wang W, Chen TC, Xie L and Song X: Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation. J Exp Clin Cancer Res. 37:2502018. View Article : Google Scholar : PubMed/NCBI

40 

Villa E, Proïcs E, Rubio-Patiño C, Obba S, Zunino B, Bossowski JP, Rozier RM, Chiche J, Mondragón L, Riley JS, et al: Parkin-independent mitophagy controls chemotherapeutic response in cancer cells. Cell Rep. 20:2846–2859. 2017. View Article : Google Scholar : PubMed/NCBI

41 

Dombi E, Mortiboys H and Poulton J: Modulating mitophagy in mitochondrial disease. Curr Med Chem. 25:5597–5612. 2018. View Article : Google Scholar : PubMed/NCBI

42 

Georgakopoulos ND, Wells G and Campanella M: The pharmacological regulation of cellular mitophagy. Nat Chem Biol. 13:136–146. 2017. View Article : Google Scholar : PubMed/NCBI

43 

Zhao Q, Ye M, Yang W, Wang M, Li M, Gu C, Zhao L, Zhang Z, Han W, Fan W, et al: Effect of Mst1 on endometriosis apoptosis and migration: Role of Drp1-related mitochondrial fission and parkin-required mitophagy. Cell Physiol Biochem. 45:1172–1190. 2018. View Article : Google Scholar : PubMed/NCBI

44 

Boyle KA, Van Wickle J, Hill RB, Marchese A, Kalyanaraman B and Dwinell MB: Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. J Biol Chem. 293:14891–14904. 2018. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Hu Y, Wang B, Wang L, Wang Z, Jian Z and Deng L: Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294. Mol Med Rep 22: 398-404, 2020.
APA
Hu, Y., Wang, B., Wang, L., Wang, Z., Jian, Z., & Deng, L. (2020). Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294. Molecular Medicine Reports, 22, 398-404. https://doi.org/10.3892/mmr.2020.11098
MLA
Hu, Y., Wang, B., Wang, L., Wang, Z., Jian, Z., Deng, L."Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294". Molecular Medicine Reports 22.1 (2020): 398-404.
Chicago
Hu, Y., Wang, B., Wang, L., Wang, Z., Jian, Z., Deng, L."Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294". Molecular Medicine Reports 22, no. 1 (2020): 398-404. https://doi.org/10.3892/mmr.2020.11098
Copy and paste a formatted citation
x
Spandidos Publications style
Hu Y, Wang B, Wang L, Wang Z, Jian Z and Deng L: Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294. Mol Med Rep 22: 398-404, 2020.
APA
Hu, Y., Wang, B., Wang, L., Wang, Z., Jian, Z., & Deng, L. (2020). Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294. Molecular Medicine Reports, 22, 398-404. https://doi.org/10.3892/mmr.2020.11098
MLA
Hu, Y., Wang, B., Wang, L., Wang, Z., Jian, Z., Deng, L."Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294". Molecular Medicine Reports 22.1 (2020): 398-404.
Chicago
Hu, Y., Wang, B., Wang, L., Wang, Z., Jian, Z., Deng, L."Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294". Molecular Medicine Reports 22, no. 1 (2020): 398-404. https://doi.org/10.3892/mmr.2020.11098
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