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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-2020 Volume 22 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Obesity ‑ a risk factor for increased COVID‑19 prevalence, severity and lethality (Review)

Demetrios Petrakis, Denisa Margină, Konstantinos Tsarouhas, Fotios Tekos, Miriana Stan, Dragana Nikitovic, Demetrios Kouretas, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 9-19
Published online on: 05 May 2020

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Review Open Access

COVID‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)

Marina Goumenou, Dimosthenis Sarigiannis, Aristidis Tsatsakis, Ourania Anesti, Anca Oana Docea, Dimitrios Petrakis, Dimitris Tsoukalas, Ronald Kostoff, Valeri Rakitskii, Demetrios A. Spandidos, Michael Aschner, Daniela Calina
Pages: 20-32
Published online on: 16 April 2020

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Article Open Access

Effect of VX‑765 on the transcriptome profile of mice spinal cords with acute injury

Jing Chen, Yu‑Qing Chen, Sai‑Nan Wang, Fei‑Xiang Duan, Yu‑Jiao Shi, Shu‑Qin Ding, Jian‑Guo Hu, He‑Zuo Lü
Pages: 33-42
Published online on: 05 May 2020

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Article Open Access

Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA‑MB‑231 cells

Ying Huang, Hui Huang, Shiying Wang, Feixiang Chen, Gang Zheng
Pages: 43-50
Published online on: 05 May 2020

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Article Open Access

MicroRNA‑19b inhibitors can attenuate the STAT3 signaling pathway in NPC C666‑1 cells

Li‑Hui Bian, Jing‑Ling Duan, Chen Zhou, Guo‑Wen Shen, Xiao‑Yu Wang, Yang Yang, Xiao‑Ling Zhang, Sheng‑Jun Xiao
Pages: 51-56
Published online on: 04 May 2020

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Article Open Access

High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer

Siman Li, Jiean Huang, Mengbin Qin, Jinxiu Zhang, Cun Liao
Pages: 57-66
Published online on: 22 April 2020

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Article Open Access

miR‑133b affects cell proliferation, invasion and chemosensitivity in renal cell carcinoma by inhibiting the ERK signaling pathway

Yuan Xu, Yuan Ma, Xiao‑Ling Liu, Sheng‑Li Gao
Pages: 67-76
Published online on: 05 May 2020

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Article Open Access

Low penetrance of hearing loss in two Chinese families carrying the mitochondrial tRNASer(UCN) mutations

Wei Peng, Yi Zhong, Xueyan Zhao, Jie Yuan
Pages: 77-86
Published online on: 30 April 2020

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Article

Expression profile of circular RNAs in the peripheral blood of neonates with hypoxic‑ischemic encephalopathy

Xiaohua Dong, Sisi Zhuang, Yun Huang, Xiaojing Yang, Yanrong Fu, Lingling Yu, Yingmin Zhao
Pages: 87-96
Published online on: 23 April 2020

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Article Open Access

7ND protein exerts inhibitory effects on both osteoclast differentiation in vitro and lipopolysaccharide‑induced bone erosion in vivo

Weilin Long, Jingjing Quan, Yiwen Liu, Jing Li, Qimei Gong, Hongwei Jiang
Pages: 97-104
Published online on: 05 May 2020

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Article Open Access

Comprehensive analysis of long non‑coding RNA using an associated competitive endogenous RNA network in Wilms tumor

Zhichao Wang, Huiyan Cheng, Lingli Qi, Dayun Sui
Pages: 105-116
Published online on: 05 May 2020

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Article Open Access

Role of the microRNA‑214/Bax axis in the progression of acute liver failure

Shaohong Wu, Xiaoping Huang, Wei Sun, Li Chen, Yan Huang, Yan Wang, Erping Luo, Ailan Qin, Weifeng Zhao, Jianhe Gan
Pages: 117-126
Published online on: 05 May 2020

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Article Open Access

High glucose contributes to the polarization of peritoneal macrophages to the M2 phenotype in vivo and in vitro

Jieshan Lin, Qingyu Kong, Wenke Hao, Wenxue Hu
Pages: 127-134
Published online on: 05 May 2020

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Article Open Access

miR‑10a‑5p inhibits osteogenic differentiation of bone marrow‑derived mesenchymal stem cells

Yingjie Zhang, Lishu Zhou, Zhaoqiang Zhang, Fei Ren, Liangjiao Chen, Zedong Lan
Pages: 135-144
Published online on: 04 May 2020

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Article Open Access

Nicotinamide mononucleotide attenuates glucocorticoid‑induced osteogenic inhibition by regulating the SIRT1/PGC‑1α signaling pathway

Rui‑Xiong Huang, Jun Tao
Pages: 145-154
Published online on: 04 May 2020

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Article Open Access

p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis

Jiuling Li, Yany Li, Lanlan Chen, Bingbing Yu, Yanan Xue, Rui Guo, Jing Su, Yanan Liu, Liankun Sun
Pages: 155-164
Published online on: 05 May 2020

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Article Open Access

MicroRNA‑125a‑mediated regulation of the mevalonate signaling pathway contributes to high glucose‑induced proliferation and migration of vascular smooth muscle cells

Dan Ye, Guo‑Hua Lou, Ai‑Chun Li, Feng‑Qin Dong, Guo‑Ping Chen, Wei‑Wei Xu, Yan‑Ning Liu, Shen‑Jiang Hu
Pages: 165-174
Published online on: 16 April 2020

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Article Open Access

Dexmedetomidine alleviated sepsis‑induced myocardial ferroptosis and septic heart injury

Chunyan Wang, Wenlin Yuan, Anmin Hu, Juan Lin, Zhengyuan Xia, Catherine F. Yang, Yalan Li, Zhongjun Zhang
Pages: 175-184
Published online on: 04 May 2020

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Article

Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer

Chun‑Chao Chang, Kuo‑Ching Chao, Chi‑Jung Huang, Chih‑Sheng Hung, Yen‑Chieh Wang
Pages: 185-192
Published online on: 22 April 2020

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Article Open Access

Identification of novel USH2A mutations in patients with autosomal recessive retinitis pigmentosa via targeted next‑generation sequencing

Xiong Zhu, Xiao Li, Wanli Tian, Yeming Yang, Kuanxiang Sun, Shuzhen Li, Xianjun Zhu
Pages: 193-200
Published online on: 22 April 2020

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Article Open Access

PNU282987 inhibits amyloid‑β aggregation by upregulating astrocytic endogenous αB‑crystallin and HSP‑70 via regulation of the α7AChR, PI3K/Akt/HSF‑1 signaling axis

Zhenkui Ren, Zhihui Dong, Peng Xie, Ju Lv, Yumei Hu, Zhizhong Guan, Chunlin Zhang, Wenfeng Yu
Pages: 201-208
Published online on: 05 May 2020

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Article Open Access

Ischemic postconditioning attenuates the inflammatory response in ischemia/reperfusion myocardium by upregulating miR‑499 and inhibiting TLR2 activation

Xin‑Yue Zhang, Zheng Huang, Qing‑Jie Li, Guo‑Qiang Zhong, Jian‑Jun Meng, Dong‑Xiao Wang, Rong‑Hui Tu
Pages: 209-218
Published online on: 30 April 2020

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Article Open Access

Urethral meatus stricture BOO stimulates bladder smooth muscle cell proliferation and pyroptosis via IL‑1β and the SGK1‑NFAT2 signaling pathway

Wang Kai, Chen Lin, Yang Jin, He Ping‑Lin, Liu Xun, Amend Bastian, Stenzl Arnulf, Xing Sha‑Sha, Luo Xu, Cui Shu
Pages: 219-226
Published online on: 24 April 2020

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Article Open Access

Elevated plasma levels of exosomal BACE1‑AS combined with the volume and thickness of the right entorhinal cortex may serve as a biomarker for the detection of Alzheimer's disease

Dewei Wang, Ping Wang, Xianli Bian, Shunliang Xu, Qingbo Zhou, Yuan Zhang, Mao Ding, Min Han, Ling Huang, Jianzhong Bi, Yuxiu Jia, Zhaohong Xie
Pages: 227-238
Published online on: 05 May 2020

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Article Open Access

Petatewalide B alleviates oxygen‑glucose deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathway

Sun Young Park, Min Hyun Cho, Mei Li, Ke Li, Geuntae Park, Young‑Whan Choi
Pages: 239-246
Published online on: 16 April 2020

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Article Open Access

Ginsenoside Rb1 reduces H2O2‑induced HUVEC dysfunction by stimulating the sirtuin‑1/AMP‑activated protein kinase pathway

Zhenda Zheng, Min Wang, Cailian Cheng, Dinghui Liu, Lin Wu, Jieming Zhu, Xiaoxian Qian
Pages: 247-256
Published online on: 28 April 2020

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Article Open Access

Excessive production of mitochondrion‑derived reactive oxygen species induced by titanium ions leads to autophagic cell death of osteoblasts via the SIRT3/SOD2 pathway

Siqian Wang, Jingyuan Yang, Tingting Lin, Shengbing Huang, Jianfeng Ma, Xin Xu
Pages: 257-264
Published online on: 24 April 2020

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Article Open Access

Hypoxia/reoxygenation activates the JNK pathway and accelerates synovial senescence

Yubiao Zhang, Siqi Zhou, Weisong Cai, Guangtao Han, Jianping Li, Mao Chen, Haohuan Li
Pages: 265-276
Published online on: 30 April 2020

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Article Open Access

Downregulation of miR‑142‑5p inhibits human aortic smooth muscle cell proliferation and migration by targeting MKL2

Wei Wu, Yuqiang Shang, Shiling Dai, Chunjun Yu, Jie Wang
Pages: 277-285
Published online on: 24 April 2020

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Article Open Access

Identification, characterization and microRNA expression profiling of side population cells in human oral squamous cell carcinoma Tca8113 cell lines

Wei Luo, Rong‑Sen Liu, Ling‑Ling E, Yang Bai, Xiang‑Pan Kong, Hua‑Wei Liu, Hao Wu, Hong‑Chen Liu
Pages: 286-296
Published online on: 16 April 2020

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Article Open Access

Mutation spectrum analysis of 29 causative genes in 43 Chinese patients with congenital hypothyroidism

Huijuan Wang, Xiaohong Kong, Yanrui Pei, Xuemei Cui, Yijie Zhu, Zixuan He, Yanxia Wang, Lirong Zhang, Lixia Zhuo, Chao Chen, Xiaoli Yan
Pages: 297-309
Published online on: 16 April 2020

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Article Open Access

Ginkgolide B inhibits hydrogen peroxide‑induced apoptosis and attenuates cytotoxicity via activating the PI3K/Akt/mTOR signaling pathway in H9c2 cells

Jin Liu, Peng Wu, Zhihui Xu, Jun Zhang, Jiabao Liu, Zhijian Yang
Pages: 310-316
Published online on: 30 April 2020

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Article Open Access

Phosphorylated GSK‑3β protects stress‑induced apoptosis of myoblasts via the PI3K/Akt signaling pathway

Meixi Liu, Xia Huang, Yihong Tian, Xiao Yan, Fang Wang, Junbo Chen, Qi Zhang, Qiang Zhang, Xiao Yuan
Pages: 317-327
Published online on: 30 April 2020

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Article Open Access

MicroRNA‑138‑5p regulates the development of spinal cord injury by targeting SIRT1

Jinchuan Chen, Rujie Qin
Pages: 328-336
Published online on: 16 April 2020

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Article Open Access

Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Pages: 337-343
Published online on: 21 April 2020

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Article Open Access

Protective effect of CTRP6 on cerebral ischemia/reperfusion injury by attenuating inflammation, oxidative stress and apoptosis in PC12 cells

Ying Li, Jie Sun, Lei Gu, Xufang Gao
Pages: 344-352
Published online on: 04 May 2020

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Article Open Access

Ginsenoside metabolite 20(S)‑protopanaxadiol promotes neural stem cell transition from a state of proliferation to differentiation by inducing autophagy and cell cycle arrest

Shali Chen, Ji He, Xiyuan Qin, Tiao Luo, Aparna Pandey, Jijia Li, Suyou Liu, Junli Luo, Qi Wang, Zhiyong Luo
Pages: 353-361
Published online on: 21 April 2020

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Article Open Access

Immunotherapy of Bacillus Calmette‑Guérin by targeting macrophages against bladder cancer in a NOD/scid IL2Rg‑/‑ mouse model

Qing‑Long Tan, Chang‑Yuan Zhou, Lin Cheng, Min Luo, Chun‑Ping Liu, Wen‑Xing Xu, Xian Zhang, Xing Zeng
Pages: 362-370
Published online on: 22 April 2020

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Article Open Access

IgE and IgG4 responses to shrimp allergen tropomyosin and its epitopes in patients from coastal areas of northern China

Junpu Li, Zhiwei Li, Deyu Kong, Shaoshen Li, Yang Yu, Huiqiang Li
Pages: 371-379
Published online on: 21 April 2020

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Article Open Access

HBV DNA integrates into upregulated ZBTB20 in patients with hepatocellular carcinoma

Zebao He, Jiansheng Zhu, Jinggang Mo, Haihong Zhao, Qiuyue Chen
Pages: 380-386
Published online on: 16 April 2020

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Article Open Access

The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling

Zhipeng Hu, Bowen Li, Zhiwei Wang, Xiaoping Hu, Min Zhang, Ruoshi Chen, Qi Wu, Fangyuan Jia
Pages: 387-397
Published online on: 22 April 2020

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Article Open Access

Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294

Yongli Hu, Bing Wang, Lie Wang, Zhenran Wang, Zhiyuan Jian, Lin Deng
Pages: 398-404
Published online on: 28 April 2020

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Article Open Access

Comprehensive analysis of aberrantly expressed long non‑coding RNAs, microRNAs, and mRNAs associated with the competitive endogenous RNA network in cervical cancer

Peng Chen, Weiyuan Zhang, Yu Chen, Xiaoli Zheng, Dong Yang
Pages: 405-415
Published online on: 05 May 2020

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Article Open Access

BPA disrupts 17‑estradiol‑mediated hepatic protection against ischemia/reperfusion injury in rat liver by upregulating the Ang II/AT1R signaling pathway

Yili Zhang, Yu Shi, Zeyu Li, Liankang Sun, Mei Zhang, Liang Yu, Shengli Wu
Pages: 416-422
Published online on: 16 April 2020

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Article Open Access

Integrated analysis of a lncRNA‑mRNA network reveals a potential mechanism underlying necrotizing enterocolitis

Wenjuan Chen, Xiangyun Yan, Tian Tian, Ru Yan, Xingyun Wang, Zhangbin Yu, Yingzheng Li, Le Zhang, Shuping Han
Pages: 423-435
Published online on: 21 April 2020

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Article Open Access

Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells

Lin Zhao, Jianming Wang, Yi Zhang, Lijun Wang, Miao Yu, Feng Wang
Pages: 436-444
Published online on: 30 April 2020

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Article Open Access

Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Pages: 445-453
Published online on: 05 May 2020

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Article Open Access

Upregulation of microRNA‑1 inhibits proliferation and metastasis of breast cancer

Jing Peng, Chenwei Yuan, Ziping Wu, Yan Wang, Wenjin Yin, Yanping Lin, Liheng Zhou, Jinsong Lu
Pages: 454-464
Published online on: 04 May 2020

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Article Open Access

WAVE3 upregulation in esophageal squamous cell carcinoma and its effect on the migration of human esophageal cancer cell lines in vitro

Xuebing Li, Jie Geng, Zhenzhen Ren, Chao Xiong, Yuqing Li, Hongchun Liu
Pages: 465-473
Published online on: 05 May 2020

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Article Open Access

MicroRNA‑21 serves an important role during PAOO‑facilitated orthodontic tooth movement

Yuanyuan Zhang, Yulou Tian, Xiaofeng Yang, Zhenjin Zhao, Cuijuan Feng, Yang Zhang
Pages: 474-482
Published online on: 04 May 2020

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Article Open Access

MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω

Chengjie Ma, Peipei Peng, Yan Zhou, Tianya Liu, Lijuan Wang, Chen Lu
Pages: 483-493
Published online on: 21 April 2020

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Article Open Access

Identification of key miRNAs and genes for mouse retinal development using a linear model

Yishen Wang, Xiao Wang, Yukang Jiang, Ruyuan Liu, Di Cao, Jianying Pan, Yan Luo
Pages: 494-506
Published online on: 21 April 2020

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Article Open Access

Heptapeptide HP3 acts as a potent inhibitor of experimental imiquimod‑induced murine psoriasis and impedes the trans‑endothelial migration of mononuclear cells

Ernesto A. Vázquez‑Sánchez, José S. Mendoza‑Figueroa, Guadalupe Gutiérrez‑Gonzalez, Luis A. Zapi‑Colín, Azael Torales‑Cardeña, Paola E. Briseño‑Lugo, Iván  Díaz‑Toalá, Juan C. Cancino‑Diaz, Sonia M. Pérez‑Tapia, Mario   E. Cancino‑Diaz, Fernando Gómez‑Chávez, Sandra Rodríguez‑Martínez
Pages: 507-515
Published online on: 05 May 2020

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Article Open Access

A novel heterozygous mutation in the HMBS gene in a patient with acute intermittent porphyria and posterior reversible encephalopathy syndrome

Yang Yang, Xiyun Chen, Huijuan Wu, Hua Peng, Wenjing Sun, Bin He, Zhengang Yuan
Pages: 516-524
Published online on: 04 May 2020

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Article Open Access

3‑N‑Butyphthalide improves learning and memory in rats with vascular cognitive impairment by activating the SIRT1/BDNF pathway

Ayong Tian, Wan Li, Qing Zai, Hui Li, Rong‑Wei Zhang
Pages: 525-533
Published online on: 04 May 2020

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Article Open Access

Tim‑3 regulates the ability of macrophages to counter lipopolysaccharide‑induced pulmonary epithelial barrier dysfunction via the PI3K/Akt pathway in epithelial cells

Yuntao Zhang, Wang Zhang
Pages: 534-542
Published online on: 04 May 2020

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Article

miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1

Yong Chen, Changqing Liu, Bingfan Xie, Shangqiu Chen, Yuan Zhuang, Shaoxia Zhang
Pages: 543-550
Published online on: 30 April 2020

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Article

A HGF‑derived peptide suppresses EMT in human lens epithelial cells via the TGF‑β/Smad and Akt/mTOR signaling pathways

Xiaobo Huang, Yulan Wang, Pei Zhang, Haidong Zou
Pages: 551-558
Published online on: 28 April 2020

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Article

Hypoxia‑inducible factor‑1α regulates Lipin1 differently in pre‑adipocytes and mature adipocytes

Yoshitaka Kihira, Yoshino Fujimura, Shuhei Tomita, Toshiaki Tamaki, Eiji Sato
Pages: 559-565
Published online on: 16 April 2020

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Article

Juglone potentiates BRAF inhibitor‑induced apoptosis in melanoma through reactive oxygen species and the p38‑p53 pathway

Zheng Li, Xiao Liu, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua Xu
Pages: 566-574
Published online on: 28 April 2020

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Effect of SIRT1 activators and inhibitors on CD44+/CD133+‑enriched non‑small cell lung cancer cells

Zuhal Eroglu, Ceren Erdem, Gulperi Oktem, Vildan Bozok Cetintas, Zekeriya Duzgun
Pages: 575-581
Published online on: 04 May 2020

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Anti‑inflammatory effects of the NF‑κB inhibitor dehydroxymethylepoxyquinomicin on ARPE‑19 cells

Yoshimasa Ando, Yasuhiko Sato, Akihiko Kudo, Takayo Watanabe, Akito Hirakata, Annabelle A. Okada, Kazuo Umezawa, Hiroshi Keino
Pages: 582-590
Published online on: 04 May 2020

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March-2026 Volume 33 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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