Journal Articles
Review
Obesity ‑ a risk factor for increased COVID‑19 prevalence, severity and lethality (Review)
Demetrios Petrakis, Denisa Margină, Konstantinos Tsarouhas, Fotios Tekos, Miriana Stan, Dragana Nikitovic, Demetrios Kouretas, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 9-19 Published online on: 05 May 2020
Review
COVID‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)
Marina Goumenou, Dimosthenis Sarigiannis, Aristidis Tsatsakis, Ourania Anesti, Anca Oana Docea, Dimitrios Petrakis, Dimitris Tsoukalas, Ronald Kostoff, Valeri Rakitskii, Demetrios A. Spandidos, Michael Aschner, Daniela Calina
Pages: 20-32 Published online on: 16 April 2020
Article
Effect of VX‑765 on the transcriptome profile of mice spinal cords with acute injury
Jing Chen, Yu‑Qing Chen, Sai‑Nan Wang, Fei‑Xiang Duan, Yu‑Jiao Shi, Shu‑Qin Ding, Jian‑Guo Hu, He‑Zuo Lü
Pages: 33-42 Published online on: 05 May 2020
Article
Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA‑MB‑231 cells
Ying Huang, Hui Huang, Shiying Wang, Feixiang Chen, Gang Zheng
Pages: 43-50 Published online on: 05 May 2020
Article
MicroRNA‑19b inhibitors can attenuate the STAT3 signaling pathway in NPC C666‑1 cells
Li‑Hui Bian, Jing‑Ling Duan, Chen Zhou, Guo‑Wen Shen, Xiao‑Yu Wang, Yang Yang, Xiao‑Ling Zhang, Sheng‑Jun Xiao
Pages: 51-56 Published online on: 04 May 2020
Article
High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer
Siman Li, Jiean Huang, Mengbin Qin, Jinxiu Zhang, Cun Liao
Pages: 57-66 Published online on: 22 April 2020
Article
miR‑133b affects cell proliferation, invasion and chemosensitivity in renal cell carcinoma by inhibiting the ERK signaling pathway
Yuan Xu, Yuan Ma, Xiao‑Ling Liu, Sheng‑Li Gao
Pages: 67-76 Published online on: 05 May 2020
Article
Low penetrance of hearing loss in two Chinese families carrying the mitochondrial tRNASer(UCN) mutations
Wei Peng, Yi Zhong, Xueyan Zhao, Jie Yuan
Pages: 77-86 Published online on: 30 April 2020
Article
Expression profile of circular RNAs in the peripheral blood of neonates with hypoxic‑ischemic encephalopathy
Xiaohua Dong, Sisi Zhuang, Yun Huang, Xiaojing Yang, Yanrong Fu, Lingling Yu, Yingmin Zhao
Pages: 87-96 Published online on: 23 April 2020
Article
7ND protein exerts inhibitory effects on both osteoclast differentiation in vitro and lipopolysaccharide‑induced bone erosion in vivo
Weilin Long, Jingjing Quan, Yiwen Liu, Jing Li, Qimei Gong, Hongwei Jiang
Pages: 97-104 Published online on: 05 May 2020
Article
Comprehensive analysis of long non‑coding RNA using an associated competitive endogenous RNA network in Wilms tumor
Zhichao Wang, Huiyan Cheng, Lingli Qi, Dayun Sui
Pages: 105-116 Published online on: 05 May 2020
Article
Role of the microRNA‑214/Bax axis in the progression of acute liver failure
Shaohong Wu, Xiaoping Huang, Wei Sun, Li Chen, Yan Huang, Yan Wang, Erping Luo, Ailan Qin, Weifeng Zhao, Jianhe Gan
Pages: 117-126 Published online on: 05 May 2020
Article
High glucose contributes to the polarization of peritoneal macrophages to the M2 phenotype in vivo and in vitro
Jieshan Lin, Qingyu Kong, Wenke Hao, Wenxue Hu
Pages: 127-134 Published online on: 05 May 2020
Article
miR‑10a‑5p inhibits osteogenic differentiation of bone marrow‑derived mesenchymal stem cells
Yingjie Zhang, Lishu Zhou, Zhaoqiang Zhang, Fei Ren, Liangjiao Chen, Zedong Lan
Pages: 135-144 Published online on: 04 May 2020
Article
Nicotinamide mononucleotide attenuates glucocorticoid‑induced osteogenic inhibition by regulating the SIRT1/PGC‑1α signaling pathway
Rui‑Xiong Huang, Jun Tao
Pages: 145-154 Published online on: 04 May 2020
Article
p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis
Jiuling Li, Yany Li, Lanlan Chen, Bingbing Yu, Yanan Xue, Rui Guo, Jing Su, Yanan Liu, Liankun Sun
Pages: 155-164 Published online on: 05 May 2020
Article
MicroRNA‑125a‑mediated regulation of the mevalonate signaling pathway contributes to high glucose‑induced proliferation and migration of vascular smooth muscle cells
Dan Ye, Guo‑Hua Lou, Ai‑Chun Li, Feng‑Qin Dong, Guo‑Ping Chen, Wei‑Wei Xu, Yan‑Ning Liu, Shen‑Jiang Hu
Pages: 165-174 Published online on: 16 April 2020
Article
Dexmedetomidine alleviated sepsis‑induced myocardial ferroptosis and septic heart injury
Chunyan Wang, Wenlin Yuan, Anmin Hu, Juan Lin, Zhengyuan Xia, Catherine F. Yang, Yalan Li, Zhongjun Zhang
Pages: 175-184 Published online on: 04 May 2020
Article
Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer
Chun‑Chao Chang, Kuo‑Ching Chao, Chi‑Jung Huang, Chih‑Sheng Hung, Yen‑Chieh Wang
Pages: 185-192 Published online on: 22 April 2020
Article
Identification of novel USH2A mutations in patients with autosomal recessive retinitis pigmentosa via targeted next‑generation sequencing
Xiong Zhu, Xiao Li, Wanli Tian, Yeming Yang, Kuanxiang Sun, Shuzhen Li, Xianjun Zhu
Pages: 193-200 Published online on: 22 April 2020
Article
PNU282987 inhibits amyloid‑β aggregation by upregulating astrocytic endogenous αB‑crystallin and HSP‑70 via regulation of the α7AChR, PI3K/Akt/HSF‑1 signaling axis
Zhenkui Ren, Zhihui Dong, Peng Xie, Ju Lv, Yumei Hu, Zhizhong Guan, Chunlin Zhang, Wenfeng Yu
Pages: 201-208 Published online on: 05 May 2020
Article
Ischemic postconditioning attenuates the inflammatory response in ischemia/reperfusion myocardium by upregulating miR‑499 and inhibiting TLR2 activation
Xin‑Yue Zhang, Zheng Huang, Qing‑Jie Li, Guo‑Qiang Zhong, Jian‑Jun Meng, Dong‑Xiao Wang, Rong‑Hui Tu
Pages: 209-218 Published online on: 30 April 2020
Article
Urethral meatus stricture BOO stimulates bladder smooth muscle cell proliferation and pyroptosis via IL‑1β and the SGK1‑NFAT2 signaling pathway
Wang Kai, Chen Lin, Yang Jin, He Ping‑Lin, Liu Xun, Amend Bastian, Stenzl Arnulf, Xing Sha‑Sha, Luo Xu, Cui Shu
Pages: 219-226 Published online on: 24 April 2020
Article
Elevated plasma levels of exosomal BACE1‑AS combined with the volume and thickness of the right entorhinal cortex may serve as a biomarker for the detection of Alzheimer's disease
Dewei Wang, Ping Wang, Xianli Bian, Shunliang Xu, Qingbo Zhou, Yuan Zhang, Mao Ding, Min Han, Ling Huang, Jianzhong Bi, Yuxiu Jia, Zhaohong Xie
Pages: 227-238 Published online on: 05 May 2020
Article
Petatewalide B alleviates oxygen‑glucose deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathway
Sun Young Park, Min Hyun Cho, Mei Li, Ke Li, Geuntae Park, Young‑Whan Choi
Pages: 239-246 Published online on: 16 April 2020
Article
Ginsenoside Rb1 reduces H2O2‑induced HUVEC dysfunction by stimulating the sirtuin‑1/AMP‑activated protein kinase pathway
Zhenda Zheng, Min Wang, Cailian Cheng, Dinghui Liu, Lin Wu, Jieming Zhu, Xiaoxian Qian
Pages: 247-256 Published online on: 28 April 2020
Article
Excessive production of mitochondrion‑derived reactive oxygen species induced by titanium ions leads to autophagic cell death of osteoblasts via the SIRT3/SOD2 pathway
Siqian Wang, Jingyuan Yang, Tingting Lin, Shengbing Huang, Jianfeng Ma, Xin Xu
Pages: 257-264 Published online on: 24 April 2020
Article
Hypoxia/reoxygenation activates the JNK pathway and accelerates synovial senescence
Yubiao Zhang, Siqi Zhou, Weisong Cai, Guangtao Han, Jianping Li, Mao Chen, Haohuan Li
Pages: 265-276 Published online on: 30 April 2020
Article
Downregulation of miR‑142‑5p inhibits human aortic smooth muscle cell proliferation and migration by targeting MKL2
Wei Wu, Yuqiang Shang, Shiling Dai, Chunjun Yu, Jie Wang
Pages: 277-285 Published online on: 24 April 2020
Article
Identification, characterization and microRNA expression profiling of side population cells in human oral squamous cell carcinoma Tca8113 cell lines
Wei Luo, Rong‑Sen Liu, Ling‑Ling E, Yang Bai, Xiang‑Pan Kong, Hua‑Wei Liu, Hao Wu, Hong‑Chen Liu
Pages: 286-296 Published online on: 16 April 2020
Article
Mutation spectrum analysis of 29 causative genes in 43 Chinese patients with congenital hypothyroidism
Huijuan Wang, Xiaohong Kong, Yanrui Pei, Xuemei Cui, Yijie Zhu, Zixuan He, Yanxia Wang, Lirong Zhang, Lixia Zhuo, Chao Chen, Xiaoli Yan
Pages: 297-309 Published online on: 16 April 2020
Article
Ginkgolide B inhibits hydrogen peroxide‑induced apoptosis and attenuates cytotoxicity via activating the PI3K/Akt/mTOR signaling pathway in H9c2 cells
Jin Liu, Peng Wu, Zhihui Xu, Jun Zhang, Jiabao Liu, Zhijian Yang
Pages: 310-316 Published online on: 30 April 2020
Article
Phosphorylated GSK‑3β protects stress‑induced apoptosis of myoblasts via the PI3K/Akt signaling pathway
Meixi Liu, Xia Huang, Yihong Tian, Xiao Yan, Fang Wang, Junbo Chen, Qi Zhang, Qiang Zhang, Xiao Yuan
Pages: 317-327 Published online on: 30 April 2020
Article
MicroRNA‑138‑5p regulates the development of spinal cord injury by targeting SIRT1
Jinchuan Chen, Rujie Qin
Pages: 328-336 Published online on: 16 April 2020
Article
Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation
Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Pages: 337-343 Published online on: 21 April 2020
Article
Protective effect of CTRP6 on cerebral ischemia/reperfusion injury by attenuating inflammation, oxidative stress and apoptosis in PC12 cells
Ying Li, Jie Sun, Lei Gu, Xufang Gao
Pages: 344-352 Published online on: 04 May 2020
Article
Ginsenoside metabolite 20(S)‑protopanaxadiol promotes neural stem cell transition from a state of proliferation to differentiation by inducing autophagy and cell cycle arrest
Shali Chen, Ji He, Xiyuan Qin, Tiao Luo, Aparna Pandey, Jijia Li, Suyou Liu, Junli Luo, Qi Wang, Zhiyong Luo
Pages: 353-361 Published online on: 21 April 2020
Article
Immunotherapy of Bacillus Calmette‑Guérin by targeting macrophages against bladder cancer in a NOD/scid IL2Rg‑/‑ mouse model
Qing‑Long Tan, Chang‑Yuan Zhou, Lin Cheng, Min Luo, Chun‑Ping Liu, Wen‑Xing Xu, Xian Zhang, Xing Zeng
Pages: 362-370 Published online on: 22 April 2020
Article
IgE and IgG4 responses to shrimp allergen tropomyosin and its epitopes in patients from coastal areas of northern China
Junpu Li, Zhiwei Li, Deyu Kong, Shaoshen Li, Yang Yu, Huiqiang Li
Pages: 371-379 Published online on: 21 April 2020
Article
HBV DNA integrates into upregulated ZBTB20 in patients with hepatocellular carcinoma
Zebao He, Jiansheng Zhu, Jinggang Mo, Haihong Zhao, Qiuyue Chen
Pages: 380-386 Published online on: 16 April 2020
Article
The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling
Zhipeng Hu, Bowen Li, Zhiwei Wang, Xiaoping Hu, Min Zhang, Ruoshi Chen, Qi Wu, Fangyuan Jia
Pages: 387-397 Published online on: 22 April 2020
Article
Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy
Yongli Hu, Bing Wang, Lie Wang, Zhenran Wang, Zhiyuan Jian, Lin Deng
Pages: 398-404 Published online on: 28 April 2020
Article
Comprehensive analysis of aberrantly expressed long non‑coding RNAs, microRNAs, and mRNAs associated with the competitive endogenous RNA network in cervical cancer
Peng Chen, Weiyuan Zhang, Yu Chen, Xiaoli Zheng, Dong Yang
Pages: 405-415 Published online on: 05 May 2020
Article
BPA disrupts 17‑estradiol‑mediated hepatic protection against ischemia/reperfusion injury in rat liver by upregulating the Ang II/AT1R signaling pathway
Yili Zhang, Yu Shi, Zeyu Li, Liankang Sun, Mei Zhang, Liang Yu, Shengli Wu
Pages: 416-422 Published online on: 16 April 2020
Article
Integrated analysis of a lncRNA‑mRNA network reveals a potential mechanism underlying necrotizing enterocolitis
Wenjuan Chen, Xiangyun Yan, Tian Tian, Ru Yan, Xingyun Wang, Zhangbin Yu, Yingzheng Li, Le Zhang, Shuping Han
Pages: 423-435 Published online on: 21 April 2020
Article
Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells
Lin Zhao, Jianming Wang, Yi Zhang, Lijun Wang, Miao Yu, Feng Wang
Pages: 436-444 Published online on: 30 April 2020
Article
Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons
Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Pages: 445-453 Published online on: 05 May 2020
Article
Upregulation of microRNA‑1 inhibits proliferation and metastasis of breast cancer
Jing Peng, Chenwei Yuan, Ziping Wu, Yan Wang, Wenjin Yin, Yanping Lin, Liheng Zhou, Jinsong Lu
Pages: 454-464 Published online on: 04 May 2020
Article
WAVE3 upregulation in esophageal squamous cell carcinoma and its effect on the migration of human esophageal cancer cell lines in vitro
Xuebing Li, Jie Geng, Zhenzhen Ren, Chao Xiong, Yuqing Li, Hongchun Liu
Pages: 465-473 Published online on: 05 May 2020
Article
MicroRNA‑21 serves an important role during PAOO‑facilitated orthodontic tooth movement
Yuanyuan Zhang, Yulou Tian, Xiaofeng Yang, Zhenjin Zhao, Cuijuan Feng, Yang Zhang
Pages: 474-482 Published online on: 04 May 2020
Article
MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω
Chengjie Ma, Peipei Peng, Yan Zhou, Tianya Liu, Lijuan Wang, Chen Lu
Pages: 483-493 Published online on: 21 April 2020
Article
Identification of key miRNAs and genes for mouse retinal development using a linear model
Yishen Wang, Xiao Wang, Yukang Jiang, Ruyuan Liu, Di Cao, Jianying Pan, Yan Luo
Pages: 494-506 Published online on: 21 April 2020
Article
Heptapeptide HP3 acts as a potent inhibitor of experimental imiquimod‑induced murine psoriasis and impedes the trans‑endothelial migration of mononuclear cells
Ernesto A. Vázquez‑Sánchez, José S. Mendoza‑Figueroa, Guadalupe Gutiérrez‑Gonzalez, Luis A. Zapi‑Colín, Azael Torales‑Cardeña, Paola E. Briseño‑Lugo, Iván Díaz‑Toalá, Juan C. Cancino‑Diaz, Sonia M. Pérez‑Tapia, Mario E. Cancino‑Diaz, Fernando Gómez‑Chávez, Sandra Rodríguez‑Martínez
Pages: 507-515 Published online on: 05 May 2020
Article
A novel heterozygous mutation in the HMBS gene in a patient with acute intermittent porphyria and posterior reversible encephalopathy syndrome
Yang Yang, Xiyun Chen, Huijuan Wu, Hua Peng, Wenjing Sun, Bin He, Zhengang Yuan
Pages: 516-524 Published online on: 04 May 2020
Article
3‑N‑Butyphthalide improves learning and memory in rats with vascular cognitive impairment by activating the SIRT1/BDNF pathway
Ayong Tian, Wan Li, Qing Zai, Hui Li, Rong‑Wei Zhang
Pages: 525-533 Published online on: 04 May 2020
Article
Tim‑3 regulates the ability of macrophages to counter lipopolysaccharide‑induced pulmonary epithelial barrier dysfunction via the PI3K/Akt pathway in epithelial cells
Yuntao Zhang, Wang Zhang
Pages: 534-542 Published online on: 04 May 2020
Article
miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1
Yong Chen, Changqing Liu, Bingfan Xie, Shangqiu Chen, Yuan Zhuang, Shaoxia Zhang
Pages: 543-550 Published online on: 30 April 2020
Article
A HGF‑derived peptide suppresses EMT in human lens epithelial cells via the TGF‑β/Smad and Akt/mTOR signaling pathways
Xiaobo Huang, Yulan Wang, Pei Zhang, Haidong Zou
Pages: 551-558 Published online on: 28 April 2020
Article
Hypoxia‑inducible factor‑1α regulates Lipin1 differently in pre‑adipocytes and mature adipocytes
Yoshitaka Kihira, Yoshino Fujimura, Shuhei Tomita, Toshiaki Tamaki, Eiji Sato
Pages: 559-565 Published online on: 16 April 2020
Article
Juglone potentiates BRAF inhibitor‑induced apoptosis in melanoma through reactive oxygen species and the p38‑p53 pathway
Zheng Li, Xiao Liu, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua Xu
Pages: 566-574 Published online on: 28 April 2020
Article
Effect of SIRT1 activators and inhibitors on CD44+/CD133+‑enriched non‑small cell lung cancer cells
Zuhal Eroglu, Ceren Erdem, Gulperi Oktem, Vildan Bozok Cetintas, Zekeriya Duzgun
Pages: 575-581 Published online on: 04 May 2020
Article
