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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-2020 Volume 22 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Obesity ‑ a risk factor for increased COVID‑19 prevalence, severity and lethality (Review)

Demetrios Petrakis, Denisa Margină, Konstantinos Tsarouhas, Fotios Tekos, Miriana Stan, Dragana Nikitovic, Demetrios Kouretas, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 9-19
Published online on: 05 May 2020

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Review Open Access

COVID‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)

Marina Goumenou, Dimosthenis Sarigiannis, Aristidis Tsatsakis, Ourania Anesti, Anca Oana Docea, Dimitrios Petrakis, Dimitris Tsoukalas, Ronald Kostoff, Valeri Rakitskii, Demetrios A. Spandidos, Michael Aschner, Daniela Calina
Pages: 20-32
Published online on: 16 April 2020

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Article Open Access

Effect of VX‑765 on the transcriptome profile of mice spinal cords with acute injury

Jing Chen, Yu‑Qing Chen, Sai‑Nan Wang, Fei‑Xiang Duan, Yu‑Jiao Shi, Shu‑Qin Ding, Jian‑Guo Hu, He‑Zuo Lü
Pages: 33-42
Published online on: 05 May 2020

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Article Open Access

Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA‑MB‑231 cells

Ying Huang, Hui Huang, Shiying Wang, Feixiang Chen, Gang Zheng
Pages: 43-50
Published online on: 05 May 2020

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Article Open Access

MicroRNA‑19b inhibitors can attenuate the STAT3 signaling pathway in NPC C666‑1 cells

Li‑Hui Bian, Jing‑Ling Duan, Chen Zhou, Guo‑Wen Shen, Xiao‑Yu Wang, Yang Yang, Xiao‑Ling Zhang, Sheng‑Jun Xiao
Pages: 51-56
Published online on: 04 May 2020

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Article Open Access

High expression of CDCA7 predicts tumor progression and poor prognosis in human colorectal cancer

Siman Li, Jiean Huang, Mengbin Qin, Jinxiu Zhang, Cun Liao
Pages: 57-66
Published online on: 22 April 2020

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Article Open Access

miR‑133b affects cell proliferation, invasion and chemosensitivity in renal cell carcinoma by inhibiting the ERK signaling pathway

Yuan Xu, Yuan Ma, Xiao‑Ling Liu, Sheng‑Li Gao
Pages: 67-76
Published online on: 05 May 2020

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Article Open Access

Low penetrance of hearing loss in two Chinese families carrying the mitochondrial tRNASer(UCN) mutations

Wei Peng, Yi Zhong, Xueyan Zhao, Jie Yuan
Pages: 77-86
Published online on: 30 April 2020

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Article

Expression profile of circular RNAs in the peripheral blood of neonates with hypoxic‑ischemic encephalopathy

Xiaohua Dong, Sisi Zhuang, Yun Huang, Xiaojing Yang, Yanrong Fu, Lingling Yu, Yingmin Zhao
Pages: 87-96
Published online on: 23 April 2020

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Article Open Access

7ND protein exerts inhibitory effects on both osteoclast differentiation in vitro and lipopolysaccharide‑induced bone erosion in vivo

Weilin Long, Jingjing Quan, Yiwen Liu, Jing Li, Qimei Gong, Hongwei Jiang
Pages: 97-104
Published online on: 05 May 2020

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Article Open Access

Comprehensive analysis of long non‑coding RNA using an associated competitive endogenous RNA network in Wilms tumor

Zhichao Wang, Huiyan Cheng, Lingli Qi, Dayun Sui
Pages: 105-116
Published online on: 05 May 2020

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Article Open Access

Role of the microRNA‑214/Bax axis in the progression of acute liver failure

Shaohong Wu, Xiaoping Huang, Wei Sun, Li Chen, Yan Huang, Yan Wang, Erping Luo, Ailan Qin, Weifeng Zhao, Jianhe Gan
Pages: 117-126
Published online on: 05 May 2020

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Article Open Access

High glucose contributes to the polarization of peritoneal macrophages to the M2 phenotype in vivo and in vitro

Jieshan Lin, Qingyu Kong, Wenke Hao, Wenxue Hu
Pages: 127-134
Published online on: 05 May 2020

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Article Open Access

miR‑10a‑5p inhibits osteogenic differentiation of bone marrow‑derived mesenchymal stem cells

Yingjie Zhang, Lishu Zhou, Zhaoqiang Zhang, Fei Ren, Liangjiao Chen, Zedong Lan
Pages: 135-144
Published online on: 04 May 2020

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Article Open Access

Nicotinamide mononucleotide attenuates glucocorticoid‑induced osteogenic inhibition by regulating the SIRT1/PGC‑1α signaling pathway

Rui‑Xiong Huang, Jun Tao
Pages: 145-154
Published online on: 04 May 2020

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Article Open Access

p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis

Jiuling Li, Yany Li, Lanlan Chen, Bingbing Yu, Yanan Xue, Rui Guo, Jing Su, Yanan Liu, Liankun Sun
Pages: 155-164
Published online on: 05 May 2020

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Article Open Access

MicroRNA‑125a‑mediated regulation of the mevalonate signaling pathway contributes to high glucose‑induced proliferation and migration of vascular smooth muscle cells

Dan Ye, Guo‑Hua Lou, Ai‑Chun Li, Feng‑Qin Dong, Guo‑Ping Chen, Wei‑Wei Xu, Yan‑Ning Liu, Shen‑Jiang Hu
Pages: 165-174
Published online on: 16 April 2020

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Article Open Access

Dexmedetomidine alleviated sepsis‑induced myocardial ferroptosis and septic heart injury

Chunyan Wang, Wenlin Yuan, Anmin Hu, Juan Lin, Zhengyuan Xia, Catherine F. Yang, Yalan Li, Zhongjun Zhang
Pages: 175-184
Published online on: 04 May 2020

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Article

Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer

Chun‑Chao Chang, Kuo‑Ching Chao, Chi‑Jung Huang, Chih‑Sheng Hung, Yen‑Chieh Wang
Pages: 185-192
Published online on: 22 April 2020

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Article Open Access

Identification of novel USH2A mutations in patients with autosomal recessive retinitis pigmentosa via targeted next‑generation sequencing

Xiong Zhu, Xiao Li, Wanli Tian, Yeming Yang, Kuanxiang Sun, Shuzhen Li, Xianjun Zhu
Pages: 193-200
Published online on: 22 April 2020

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Article Open Access

PNU282987 inhibits amyloid‑β aggregation by upregulating astrocytic endogenous αB‑crystallin and HSP‑70 via regulation of the α7AChR, PI3K/Akt/HSF‑1 signaling axis

Zhenkui Ren, Zhihui Dong, Peng Xie, Ju Lv, Yumei Hu, Zhizhong Guan, Chunlin Zhang, Wenfeng Yu
Pages: 201-208
Published online on: 05 May 2020

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Article Open Access

Ischemic postconditioning attenuates the inflammatory response in ischemia/reperfusion myocardium by upregulating miR‑499 and inhibiting TLR2 activation

Xin‑Yue Zhang, Zheng Huang, Qing‑Jie Li, Guo‑Qiang Zhong, Jian‑Jun Meng, Dong‑Xiao Wang, Rong‑Hui Tu
Pages: 209-218
Published online on: 30 April 2020

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Article Open Access

Urethral meatus stricture BOO stimulates bladder smooth muscle cell proliferation and pyroptosis via IL‑1β and the SGK1‑NFAT2 signaling pathway

Wang Kai, Chen Lin, Yang Jin, He Ping‑Lin, Liu Xun, Amend Bastian, Stenzl Arnulf, Xing Sha‑Sha, Luo Xu, Cui Shu
Pages: 219-226
Published online on: 24 April 2020

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Article Open Access

Elevated plasma levels of exosomal BACE1‑AS combined with the volume and thickness of the right entorhinal cortex may serve as a biomarker for the detection of Alzheimer's disease

Dewei Wang, Ping Wang, Xianli Bian, Shunliang Xu, Qingbo Zhou, Yuan Zhang, Mao Ding, Min Han, Ling Huang, Jianzhong Bi, Yuxiu Jia, Zhaohong Xie
Pages: 227-238
Published online on: 05 May 2020

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Article Open Access

Petatewalide B alleviates oxygen‑glucose deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathway

Sun Young Park, Min Hyun Cho, Mei Li, Ke Li, Geuntae Park, Young‑Whan Choi
Pages: 239-246
Published online on: 16 April 2020

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Article Open Access

Ginsenoside Rb1 reduces H2O2‑induced HUVEC dysfunction by stimulating the sirtuin‑1/AMP‑activated protein kinase pathway

Zhenda Zheng, Min Wang, Cailian Cheng, Dinghui Liu, Lin Wu, Jieming Zhu, Xiaoxian Qian
Pages: 247-256
Published online on: 28 April 2020

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Article Open Access

Excessive production of mitochondrion‑derived reactive oxygen species induced by titanium ions leads to autophagic cell death of osteoblasts via the SIRT3/SOD2 pathway

Siqian Wang, Jingyuan Yang, Tingting Lin, Shengbing Huang, Jianfeng Ma, Xin Xu
Pages: 257-264
Published online on: 24 April 2020

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Article Open Access

Hypoxia/reoxygenation activates the JNK pathway and accelerates synovial senescence

Yubiao Zhang, Siqi Zhou, Weisong Cai, Guangtao Han, Jianping Li, Mao Chen, Haohuan Li
Pages: 265-276
Published online on: 30 April 2020

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Article Open Access

Downregulation of miR‑142‑5p inhibits human aortic smooth muscle cell proliferation and migration by targeting MKL2

Wei Wu, Yuqiang Shang, Shiling Dai, Chunjun Yu, Jie Wang
Pages: 277-285
Published online on: 24 April 2020

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Article Open Access

Identification, characterization and microRNA expression profiling of side population cells in human oral squamous cell carcinoma Tca8113 cell lines

Wei Luo, Rong‑Sen Liu, Ling‑Ling E, Yang Bai, Xiang‑Pan Kong, Hua‑Wei Liu, Hao Wu, Hong‑Chen Liu
Pages: 286-296
Published online on: 16 April 2020

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Article Open Access

Mutation spectrum analysis of 29 causative genes in 43 Chinese patients with congenital hypothyroidism

Huijuan Wang, Xiaohong Kong, Yanrui Pei, Xuemei Cui, Yijie Zhu, Zixuan He, Yanxia Wang, Lirong Zhang, Lixia Zhuo, Chao Chen, Xiaoli Yan
Pages: 297-309
Published online on: 16 April 2020

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Article Open Access

Ginkgolide B inhibits hydrogen peroxide‑induced apoptosis and attenuates cytotoxicity via activating the PI3K/Akt/mTOR signaling pathway in H9c2 cells

Jin Liu, Peng Wu, Zhihui Xu, Jun Zhang, Jiabao Liu, Zhijian Yang
Pages: 310-316
Published online on: 30 April 2020

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Article Open Access

Phosphorylated GSK‑3β protects stress‑induced apoptosis of myoblasts via the PI3K/Akt signaling pathway

Meixi Liu, Xia Huang, Yihong Tian, Xiao Yan, Fang Wang, Junbo Chen, Qi Zhang, Qiang Zhang, Xiao Yuan
Pages: 317-327
Published online on: 30 April 2020

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Article Open Access

MicroRNA‑138‑5p regulates the development of spinal cord injury by targeting SIRT1

Jinchuan Chen, Rujie Qin
Pages: 328-336
Published online on: 16 April 2020

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Article Open Access

Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation Retraction in /10.3892/mmr.2026.13838

Fen Chen, Haiyang Xie, Haiwei Bao, Laurencia Violetta, Shusen Zheng
Pages: 337-343
Published online on: 21 April 2020

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Article Open Access

Protective effect of CTRP6 on cerebral ischemia/reperfusion injury by attenuating inflammation, oxidative stress and apoptosis in PC12 cells

Ying Li, Jie Sun, Lei Gu, Xufang Gao
Pages: 344-352
Published online on: 04 May 2020

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Article Open Access

Ginsenoside metabolite 20(S)‑protopanaxadiol promotes neural stem cell transition from a state of proliferation to differentiation by inducing autophagy and cell cycle arrest

Shali Chen, Ji He, Xiyuan Qin, Tiao Luo, Aparna Pandey, Jijia Li, Suyou Liu, Junli Luo, Qi Wang, Zhiyong Luo
Pages: 353-361
Published online on: 21 April 2020

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Article Open Access

Immunotherapy of Bacillus Calmette‑Guérin by targeting macrophages against bladder cancer in a NOD/scid IL2Rg‑/‑ mouse model

Qing‑Long Tan, Chang‑Yuan Zhou, Lin Cheng, Min Luo, Chun‑Ping Liu, Wen‑Xing Xu, Xian Zhang, Xing Zeng
Pages: 362-370
Published online on: 22 April 2020

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Article Open Access

IgE and IgG4 responses to shrimp allergen tropomyosin and its epitopes in patients from coastal areas of northern China

Junpu Li, Zhiwei Li, Deyu Kong, Shaoshen Li, Yang Yu, Huiqiang Li
Pages: 371-379
Published online on: 21 April 2020

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Article Open Access

HBV DNA integrates into upregulated ZBTB20 in patients with hepatocellular carcinoma

Zebao He, Jiansheng Zhu, Jinggang Mo, Haihong Zhao, Qiuyue Chen
Pages: 380-386
Published online on: 16 April 2020

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Article Open Access

The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling

Zhipeng Hu, Bowen Li, Zhiwei Wang, Xiaoping Hu, Min Zhang, Ruoshi Chen, Qi Wu, Fangyuan Jia
Pages: 387-397
Published online on: 22 April 2020

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Article Open Access

Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy Retraction in /10.3892/mmr.2024.13294

Yongli Hu, Bing Wang, Lie Wang, Zhenran Wang, Zhiyuan Jian, Lin Deng
Pages: 398-404
Published online on: 28 April 2020

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Article Open Access

Comprehensive analysis of aberrantly expressed long non‑coding RNAs, microRNAs, and mRNAs associated with the competitive endogenous RNA network in cervical cancer

Peng Chen, Weiyuan Zhang, Yu Chen, Xiaoli Zheng, Dong Yang
Pages: 405-415
Published online on: 05 May 2020

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Article Open Access

BPA disrupts 17‑estradiol‑mediated hepatic protection against ischemia/reperfusion injury in rat liver by upregulating the Ang II/AT1R signaling pathway

Yili Zhang, Yu Shi, Zeyu Li, Liankang Sun, Mei Zhang, Liang Yu, Shengli Wu
Pages: 416-422
Published online on: 16 April 2020

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Article Open Access

Integrated analysis of a lncRNA‑mRNA network reveals a potential mechanism underlying necrotizing enterocolitis

Wenjuan Chen, Xiangyun Yan, Tian Tian, Ru Yan, Xingyun Wang, Zhangbin Yu, Yingzheng Li, Le Zhang, Shuping Han
Pages: 423-435
Published online on: 21 April 2020

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Article Open Access

Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells

Lin Zhao, Jianming Wang, Yi Zhang, Lijun Wang, Miao Yu, Feng Wang
Pages: 436-444
Published online on: 30 April 2020

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Article Open Access

Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Pages: 445-453
Published online on: 05 May 2020

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Article Open Access

Upregulation of microRNA‑1 inhibits proliferation and metastasis of breast cancer

Jing Peng, Chenwei Yuan, Ziping Wu, Yan Wang, Wenjin Yin, Yanping Lin, Liheng Zhou, Jinsong Lu
Pages: 454-464
Published online on: 04 May 2020

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Article Open Access

WAVE3 upregulation in esophageal squamous cell carcinoma and its effect on the migration of human esophageal cancer cell lines in vitro

Xuebing Li, Jie Geng, Zhenzhen Ren, Chao Xiong, Yuqing Li, Hongchun Liu
Pages: 465-473
Published online on: 05 May 2020

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Article Open Access

MicroRNA‑21 serves an important role during PAOO‑facilitated orthodontic tooth movement

Yuanyuan Zhang, Yulou Tian, Xiaofeng Yang, Zhenjin Zhao, Cuijuan Feng, Yang Zhang
Pages: 474-482
Published online on: 04 May 2020

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Article Open Access

MicroRNA‑93 promotes angiogenesis and attenuates remodeling via inactivation of the Hippo/Yap pathway by targeting Lats2 after myocardial infarctionω

Chengjie Ma, Peipei Peng, Yan Zhou, Tianya Liu, Lijuan Wang, Chen Lu
Pages: 483-493
Published online on: 21 April 2020

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Article Open Access

Identification of key miRNAs and genes for mouse retinal development using a linear model

Yishen Wang, Xiao Wang, Yukang Jiang, Ruyuan Liu, Di Cao, Jianying Pan, Yan Luo
Pages: 494-506
Published online on: 21 April 2020

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Article Open Access

Heptapeptide HP3 acts as a potent inhibitor of experimental imiquimod‑induced murine psoriasis and impedes the trans‑endothelial migration of mononuclear cells

Ernesto A. Vázquez‑Sánchez, José S. Mendoza‑Figueroa, Guadalupe Gutiérrez‑Gonzalez, Luis A. Zapi‑Colín, Azael Torales‑Cardeña, Paola E. Briseño‑Lugo, Iván  Díaz‑Toalá, Juan C. Cancino‑Diaz, Sonia M. Pérez‑Tapia, Mario   E. Cancino‑Diaz, Fernando Gómez‑Chávez, Sandra Rodríguez‑Martínez
Pages: 507-515
Published online on: 05 May 2020

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Article Open Access

A novel heterozygous mutation in the HMBS gene in a patient with acute intermittent porphyria and posterior reversible encephalopathy syndrome

Yang Yang, Xiyun Chen, Huijuan Wu, Hua Peng, Wenjing Sun, Bin He, Zhengang Yuan
Pages: 516-524
Published online on: 04 May 2020

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Article Open Access

3‑N‑Butyphthalide improves learning and memory in rats with vascular cognitive impairment by activating the SIRT1/BDNF pathway

Ayong Tian, Wan Li, Qing Zai, Hui Li, Rong‑Wei Zhang
Pages: 525-533
Published online on: 04 May 2020

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Article Open Access

Tim‑3 regulates the ability of macrophages to counter lipopolysaccharide‑induced pulmonary epithelial barrier dysfunction via the PI3K/Akt pathway in epithelial cells

Yuntao Zhang, Wang Zhang
Pages: 534-542
Published online on: 04 May 2020

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Article

miR‑96 exerts an oncogenic role in the progression of cervical cancer by targeting CAV‑1

Yong Chen, Changqing Liu, Bingfan Xie, Shangqiu Chen, Yuan Zhuang, Shaoxia Zhang
Pages: 543-550
Published online on: 30 April 2020

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Article

A HGF‑derived peptide suppresses EMT in human lens epithelial cells via the TGF‑β/Smad and Akt/mTOR signaling pathways

Xiaobo Huang, Yulan Wang, Pei Zhang, Haidong Zou
Pages: 551-558
Published online on: 28 April 2020

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Article

Hypoxia‑inducible factor‑1α regulates Lipin1 differently in pre‑adipocytes and mature adipocytes

Yoshitaka Kihira, Yoshino Fujimura, Shuhei Tomita, Toshiaki Tamaki, Eiji Sato
Pages: 559-565
Published online on: 16 April 2020

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Article

Juglone potentiates BRAF inhibitor‑induced apoptosis in melanoma through reactive oxygen species and the p38‑p53 pathway

Zheng Li, Xiao Liu, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua Xu
Pages: 566-574
Published online on: 28 April 2020

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Effect of SIRT1 activators and inhibitors on CD44+/CD133+‑enriched non‑small cell lung cancer cells

Zuhal Eroglu, Ceren Erdem, Gulperi Oktem, Vildan Bozok Cetintas, Zekeriya Duzgun
Pages: 575-581
Published online on: 04 May 2020

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Anti‑inflammatory effects of the NF‑κB inhibitor dehydroxymethylepoxyquinomicin on ARPE‑19 cells

Yoshimasa Ando, Yasuhiko Sato, Akihiko Kudo, Takayo Watanabe, Akito Hirakata, Annabelle A. Okada, Kazuo Umezawa, Hiroshi Keino
Pages: 582-590
Published online on: 04 May 2020

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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