|
1
|
Swanson A, Wolf T, Sitzmann A and Willette
AA: Neuroinflammation in Alzheimer's disease: Pleiotropic roles for
cytokines and neuronal pentraxins. Behav Brain Res. 347:49–56.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Suwanna N, Thangnipon W and Soi-Ampornkul
R: Neuroprotective effects of diarylpropionitrile against β-amyloid
peptide-induced neurotoxicity in rat cultured cortical neurons.
Neurosci Lett. 578:44–49. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Latta-Mahieu M, Elmer B, Bretteville A,
Wang Y, Lopez-Grancha M, Goniot P, Moindrot N, Ferrari P, Blanc V,
Schussler N, et al: Systemic immune-checkpoint blockade with
anti-PD1 antibodies does not alter cerebral amyloid-β burden in
several amyloid transgenic mouse models. Glia. 66:492–504. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Miron J, Picard C, Frappier J, Dea D,
Théroux L and Poirier J: TLR4 gene expression and pro-inflammatory
cytokines in Alzheimer's disease and in response to hippocampal
deafferentation in rodents. J Alzheimers Dis. 63:1547–1556. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cui W, Sun Y, Wang Z, Xu C, Peng Y and Li
R: Liver X receptor activation attenuates inflammatory response and
protects cholinergic neurons in APP/PS1 transgenic mice.
Neuroscience. 210:200–210. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Yang Y, Wang Y, Zhao M, Jia H, Li B and
Xing D: Tormentic acid inhibits IL-1β-induced chondrocyte apoptosis
by activating the PI3K/Akt signaling pathway. Mol Med Rep.
17:4753–4758. 2018.PubMed/NCBI
|
|
7
|
Jiang WP, Huang SS, Matsuda Y, Saito H,
Uramaru N, Ho HY, Wu JB and Huang GJ: Protective effects of
tormentic acid, a major component of suspension cultures of
eriobotrya japonica cells, on acetaminophen-induced hepatotoxicity
in mice. Molecules. 22(pii): E8302017. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wang YL, Sun GY, Zhang Y, He JJ, Zheng S
and Lin JN: Tormentic acid inhibits H2O2-induced oxidative stress
and inflammation in rat vascular smooth muscle cells via inhibition
of the NF-κB signaling pathway. Mol Med Rep. 14:3559–3564. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Cui W, Sun Y, Wang Z, Xu C, Xu L, Wang F,
Chen Z, Peng Y and Li R: Activation of liver X receptor decreases
BACE1 expression and activity by reducing membrane cholesterol
levels. Neurochem Res. 36:1910–1921. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Casal C, Serratosa J and Tusell JM:
Effects of beta-AP peptides on activation of the transcription
factor NF-kappaB and in cell proliferation in glial cell cultures.
Neurosci Res. 48:315–323. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chen G, Bower KA, Ma C, Fang S, Thiele CJ
and Luo J: Glycogen synthase kinase 3beta (GSK3beta) mediates
6-hydroxydopamine-induced neuronal death. FASEB J. 18:1162–1164.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gao Y, Zhuang Z, Lu Y, Tao T, Zhou Y, Liu
G, Wang H, Zhang D, Wu L, Dai H, et al: Curcumin mitigates
neuro-inflammation by modulating microglia polarization through
inhibiting TLR4 axis signaling pathway following experimental
subarachnoid hemorrhage. Front Neurosci. 13:12232019. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Taga M, Minett T, Classey J, Matthews FE,
Brayne C, Ince PG, Nicoll JA, Hugon J and Boche D; MRC CFAS, :
Metaflammasome components in the human brain: A role in dementia
with Alzheimer's pathology? Brain Pathol. 27:266–275. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Martínez-Mármol R, Mohannak N, Qian L,
Wang T, Gormal RS, Ruitenberg MJ, Vanhaesebroeck B, Coulson EJ and
Meunier FA: p110δ PI3-kinase inhibition perturbs APP and TNFα
trafficking, reduces plaque burden, dampens neuroinflammation, and
prevents cognitive decline in an Alzheimer's disease mouse model. J
Neurosci. 39:7976–7991. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Casali BT, Reed-Geaghan EG and Landreth
GE: Nuclear receptor agonist-driven modification of inflammation
and amyloid pathology enhances and sustains cognitive improvements
in a mouse model of Alzheimer's disease. J Neuroinflammation.
15:432018. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yang Z, Kuboyama T and Tohda C: Naringenin
promotes microglial M2 polarization and Aβ degradation enzyme
expression. Phytother Res. 33:1114–1121. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Feng J, Wang JX, Du YH, Liu Y, Zhang W,
Chen JF, Liu YJ, Zheng M, Wang KJ and He GQ: Dihydromyricetin
inhibits microglial activation and neuroinflammation by suppressing
NLRP3 inflammasome activation in APP/PS1 transgenic mice. CNS
Neurosci Ther. 24:1207–1218. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ma A, Wang Y and Zhang Q: Tormentic acid
reduces inflammation in BV-2 microglia by activating the liver X
receptor alpha. Neuroscience. 287:9–14. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Jian CX, Li MZ, Zheng WY, He Y, Ren Y, Wu
ZM, Fan QS, Hu YH and Li CJ: Tormentic acid inhibits LPS-induced
inflammatory response in human gingival fibroblasts via inhibition
of TLR4-mediated NF-κB and MAPK signalling pathway. Arch Oral Biol.
60:1327–1332. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chang CT, Huang SS, Lin SS, Amagaya S, Ho
HY, Hou WC, Shie PH, Wu JB and Huang GJ: Anti-inflammatory
activities of tormentic acid from suspension cells of Eriobotrya
Japonicaex vivo and in vivo. Food Chem. 127:1131–1137. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Piazza FV, Segabinazi E, de Meireles ALF,
Mega F, Spindler CF, Augustin OA, Salvalaggio GDS, Achaval M, Kruse
MS, Coirini H, et al: Severe uncontrolled maternal hyperglycemia
induces microsomia and neurodevelopment delay accompanied by
apoptosis, cellular survival, and neuroinflammatory deregulation in
rat offspring hippocampus. Cell Mol Neurobiol. 39:401–414. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Chen Y, Yin M, Cao X, Hu G and Xiao M:
Pro- and anti-inflammatory effects of high cholesterol diet on aged
brain. Aging Dis. 9:374–390. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hay M, Polt R, Heien ML, Vanderah TW,
Largent-Milnes TM, Rodgers K, Falk T, Bartlett MJ, Doyle KP and
Konhilas JP: A novel angiotensin-(1–7) glycosylated mas receptor
agonist for treating vascular cognitive impairment and
inflammation-related memory dysfunction. J Pharmacol Exp Ther.
369:9–25. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Qin S, Yang C, Huang W, Du S, Mai H, Xiao
J and Lü T: Sulforaphane attenuates microglia-mediated neuronal
necroptosis through down-regulation of MAPK/NF-κB signaling
pathways in LPS-activated BV-2 microglia. Pharmacol Res.
133:218–235. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
He D, Huang B, Fu S, Li Y, Ran X, Liu Y,
Chen G, Liu J and Liu D: Tubeimoside I protects dopaminergic
neurons against inflammation-mediated damage in lipopolysaccharide
(LPS)-evoked model of Parkinson's disease in rats. Int J Mol Sci.
19(pii): E22422018. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lim HS, Kim BY, Kim YJ and Jeong SJ:
Phytochemical allylguaiacol exerts a neuroprotective effect on
hippocampal cells and ameliorates scopolamine-induced memory
impairment in mice. Behav Brain Res. 339:261–268. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Huang Z, Liang N, Damdimopoulos A, Fan R
and Treuter E: G protein pathway suppressor 2 (GPS2) links
inflammation and cholesterol efflux by controlling
lipopolysaccharide-induced ATP-binding cassette transporter A1
expression in macrophages. FASEB J. 33:1631–1643. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Ou Z, Kong X, Sun X, He X, Zhang L, Gong
Z, Huang J, Xu B, Long D, Li J, et al: Metformin treatment prevents
amyloid plaque deposition and memory impairment in APP/PS1 mice.
Brain Behav Immun. 69:351–363. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Simmons LJ, Surles-Zeigler MC, Li Y, Ford
GD, Newman GD and Ford BD: Regulation of inflammatory responses by
neuregulin-1 in brain ischemia and microglial cells in vitro
involves the NF-kappa B pathway. J Neuroinflammation. 13:2372016.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yang Y, Wang Y, Wang Y, Zhao M, Jia H, Li
B and Xing D: Tormentic acid inhibits IL-1β-induced inflammatory
response in human osteoarthritic chondrocytes. Inflammation.
39:1151–1159. 2016.PubMed/NCBI
|
|
31
|
Yao Y, Sun F and Lei M: miR-25 inhibits
sepsis-induced cardiomyocyte apoptosis by targetting PTEN. Biosci
Rep. 38(pii): BSR201715112018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yousefi N, Sotoodehnejadnematalahi F,
Heshmati-Fakhr N, Sayyah M, Hoseini M, Ghassemi S, Aliakbari S and
Pourbadie HG: Prestimulation of microglia through TLR4 pathway
promotes interferon beta expression in a rat model of Alzheimer's
disease. J Mol Neurosci. 67:495–503. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Gabbouj S, Natunen T, Koivisto H,
Jokivarsi K, Takalo M, Marttinen M, Wittrahm R, Kemppainen S,
Naderi R, Posado-Fernandez A, et al: Intranasal insulin activates
Akt2 signaling pathway in the hippocampus of wild-type but not in
APP/PS1 Alzheimer model mice. Neurobiol Aging. 75:98–108. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Tible M, Mouton LF, Schmitt J, Giralt A,
Farid K, Thomasseau S, Gourmaud S, Paquet C, Rondi RL, Meurs E, et
al: PKR knockout in the 5×FAD model of Alzheimer's disease reveals
beneficial effects on spatial memory and brain lesions. Aging Cell.
18:e128872019. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yin P, Wang S, Wei Y, Wang X, Zhang J, Yin
X, Feng J and Zhu M: Maresin1 decreased microglial chemotaxis and
ameliorated inflammation induced by amyloid-β42 in neuron-microglia
co-culture models. J Alzheimers Dis. 73:503–515. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Basso L, Lapointe TK, Iftinca M, Marsters
C, Hollenberg MD, Kurrasch DM and Altier C:
Granulocyte-colony-stimulating factor (G-CSF) signaling in spinal
microglia drives visceral sensitization following colitis. Proc
Natl Acad Sci USA. 114:11235–11240. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Lin X, Zhang S, Huang R, Tan S, Liang S,
Wu X, Zhuo L and Huang Q: Protective effect of tormentic acid from
Potentilla chinensis against
lipopolysaccharide/D-galactosamine induced fulminant hepatic
failure in mice. Int Immunopharmacol. 19:365–372. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Loizzo MR, Bonesi M, Passalacqua NG, Saab
A, Menichini F and Tundis R: Antiproliferative activities on renal,
prostate and melanoma cancer cell lines of Sarcopoterium spinosum
aerial parts and its major constituent tormentic acid. Anticancer
Agents Med Chem. 13:768–776. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Cui W, Tao J, Wang Z, Ren M, Zhang Y, Sun
Y, Peng Y and Li R: Neuregulin1beta1 antagonizes apoptosis via
ErbB4-dependent activation of PI3-kinase/Akt in APP/PS1 transgenic
mice. Neurochem Res. 38:2237–2246. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Snow AD, Castillo GM, Nguyen BP, Choi PY,
Cummings JA, Cam J, Hu Q, Lake T, Pan W, Kastin AJ, et al: The
Amazon rain forest plant Uncaria tomentosa (cat's claw) and its
specific proanthocyanidin constituents are potent inhibitors and
reducers of both brain plaques and tangles. Sci Rep. 9:5612019.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Logue MW, Panizzon MS, Elman JA, Gillespie
NA, Hatton SN, Gustavson DE, Andreassen OA, Dale AM, Franz CE,
Lyons MJ, et al: Use of an Alzheimer's disease polygenic risk score
to identify mild cognitive impairment in adults in their 50s. Mol
Psychiatry. 24:421–430. 2019. View Article : Google Scholar : PubMed/NCBI
|
