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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2020 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review)

Saizhi Jiang, Jamie L. Young, Kai Wang, Yan Qian, Lu Cai
Pages: 603-611
Published online on: 22 May 2020

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Review

c‑Abl‑mediated tyrosine phosphorylation of DNA damage response proteins and implications in important cellular functions (Review)

Ameer Ali Bohio, Ruoxi Wang, Xianlu Zeng, Xueqing Ba
Pages: 612-619
Published online on: 18 May 2020

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Article Open Access

Identification of prognostic biomarkers and drug target prediction for colon cancer according to a competitive endogenous RNA network

Daojun Hu, Boke Zhang, Miao Yu, Wenjie Shi, Li Zhang
Pages: 620-632
Published online on: 22 May 2020

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Article Open Access

miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4

Yujing Fan, Kuanyu Wang
Pages: 633-642
Published online on: 18 May 2020

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Article Open Access

Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation

Ayano Tada, Haruyuki Nakayama‑Imaohji, Hisashi Yamasaki, Miad Elahi, Tamiko Nagao, Hirofumi Yagi, Masao Ishikawa, Koji Shibuya, Tomomi Kuwahara
Pages: 643-650
Published online on: 07 May 2020

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Article Open Access

TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats Corrigendum in /10.3892/mmr.2021.12144

Zhi‑Peng Lin, Hui‑Li Lin, Xue‑Ping Yu, Yi‑Juan Zheng, Si‑Yu Cheng
Pages: 651-660
Published online on: 07 May 2020

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Article Open Access

miR‑29 mediates exercise‑induced skeletal muscle angiogenesis by targeting VEGFA, COL4A1 and COL4A2 via the PI3K/Akt signaling pathway

Lei Chen, Jun Bai, Yanfei Li
Pages: 661-670
Published online on: 20 May 2020

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Article Open Access

Saccharomyces boulardii modulates necrotizing enterocolitis in neonatal mice by regulating the sirtuin 1/NF‑κB pathway and the intestinal microbiota

Kun Zhang, Xi Zhang, Anping Lv, Sainan Fan, Jinping Zhang
Pages: 671-680
Published online on: 07 May 2020

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Article Open Access

STAR mutations causing non‑classical lipoid adrenal hyperplasia manifested as familial glucocorticoid deficiency

Yuanyuan Luo, Ruojing Bai, Zhifang Wang, Xiaofan Zhu, Jingjing Xing, Xialian Li
Pages: 681-686
Published online on: 07 May 2020

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Article Open Access

Long non‑coding RNA NNT‑AS1 knockdown represses the progression of gastric cancer via modulating the miR‑142‑5p/SOX4/Wnt/β‑catenin signaling pathway

Jianfeng Zhang, Kai Zhang, Yingkui Hou
Pages: 687-696
Published online on: 18 May 2020

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Article Open Access

Anticancer effect of caudatin in diethylnitrosamine‑induced hepatocarcinogenesis in rats

Jie Song, Wenbo Ding, Bojia Liu, Dan Liu, Zhi Xia, Li Zhang, Li Cui, Yi Luo, Xiaobin Jia, Liang Feng
Pages: 697-706
Published online on: 07 May 2020

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Article Open Access

Effects of dihydroartemisinin on the gut microbiome of mice

Yanyan Liu, Yanhong Yang, Yuting Lei, Lanxiang Yang, Xueying Zhang, Jian Yuan, Zili Lei
Pages: 707-714
Published online on: 20 May 2020

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Article Open Access

Effects of human umbilical cord mesenchymal stem cells derived from exosomes on migration ability of endometrial glandular epithelial cells

Ying Feng, Fuliang Zhan, Yanying Zhong, Buzhen Tan
Pages: 715-722
Published online on: 07 May 2020

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Article Open Access

Long non‑coding RNA FLVCR1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑30b‑3p

Weida Gao, Hongbin Li, Yang Liu, Yao Zhang, Hong Zhao, Fei Liu
Pages: 723-732
Published online on: 15 May 2020

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Article Open Access

Syntenin regulates melanogenesis via the p38 MAPK pathway

Lijun Sun, Chunyan Guo, Liting Yan, Huijin Li, Jingying Sun, Xueping Huo, Xin Xie, Jun Hu
Pages: 733-738
Published online on: 07 May 2020

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Article Open Access

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model

Weigang Cui, Chunli Sun, Yuqi Ma, Songtao Wang, Xianwei Wang, Yinghua Zhang
Pages: 739-750
Published online on: 18 May 2020

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Article Open Access

Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture

Zhidong Zhou, Hejian Li, Hongchun Li, Jing Zhang, Kaiwen Fu, Cao Cao, Fumou Deng, Jun Luo
Pages: 751-762
Published online on: 20 May 2020

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Article Open Access

Effects of sacral nerve electrical stimulation on 5‑HT and 5‑HT3AR/5‑HT4R levels in the colon and sacral cord of acute spinal cord injury rat models

Yi Zhu, Jie Cheng, Jichao Yin, Yujie Yang, Jiabao Guo, Wenyi  Zhang, Bing Xie, Haixia Lu, Dingjun Hao
Pages: 763-773
Published online on: 15 May 2020

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Article Open Access

NCTD elicits proapoptotic and antiglycolytic effects on colorectal cancer cells via modulation of Fam46c expression and inhibition of ERK1/2 signaling Retraction in /10.3892/mmr.2023.13078

Shiqiang Zhang, Yun Yang, Yunwei Hua, Chen Hu, Yi Zhong
Pages: 774-782
Published online on: 18 May 2020

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Article Open Access

Downregulation of microRNA‑106a‑5p alleviates ox‑LDL‑mediated endothelial cell injury by targeting STAT3

Ying Hu, Rong Xu, Yue He, Zhibo Zhao, Xudong Mao, Ling Lin, Jun Hu
Pages: 783-791
Published online on: 14 May 2020

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Article Open Access

Circulating mRNA and microRNA profiling analysis in patients with ischemic stroke

Sujuan Sun, Litao Li, Lipeng Dong, Jinming Cheng, Congying Zhao, Chu Bao, Hebo Wang
Pages: 792-802
Published online on: 14 May 2020

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Article Open Access

Effects of miR‑195‑5p on cell proliferation and apoptosis in gestational diabetes mellitus via targeting EZH2

Xiaojie Liao, Zhuolin Zhou, Xiaoliu Zhang
Pages: 803-809
Published online on: 12 May 2020

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Article Open Access

Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells

Qiong Wang, Wenwen Zhu, Geqiong Xiao, Mengyu Ding, Jian Chang, Hui Liao
Pages: 810-818
Published online on: 22 May 2020

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Article Open Access

Expression and clinical value of SALL4 in renal cell carcinomas

Jianping Che, Pengfei Wu, Guangchun Wang, Xudong Yao, Junhua Zheng, Changcheng Guo
Pages: 819-827
Published online on: 22 May 2020

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Article Open Access

Clinical characteristics and prognostic significance of TCGA and ACRG classification in gastric cancer among the Chinese population

Qiang Wang, Qi Xie, Yang Liu, Honghai Guo, Yingchun Ren, Jianke Li, Qun Zhao
Pages: 828-840
Published online on: 22 May 2020

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Article Open Access

Downregulated miR‑29a promotes B cell overactivation by upregulating Crk‑like protein in systemic lupus erythematosus

Xinyu Shi, Lulu Ye, Shuqi Xu, Gangqiang Guo, Ziyi Zuo, Mengke Ye, Lejiang Zhu, Baoqing Li, Xiangyang Xue, Qiaoai Lin, Xiaokai Ding
Pages: 841-849
Published online on: 21 May 2020

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Article Open Access

miR‑217‑5p regulates myogenesis in skeletal muscle stem cells by targeting FGFR2

Menghai Zhu, Gang Chen, Yi Yang, Jiantao Yang, Bengang Qin, Liqiang Gu
Pages: 850-858
Published online on: 07 May 2020

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Article Open Access

Identification of potential crucial genes and molecular mechanisms in glioblastoma multiforme by bioinformatics analysis

Xiaojie Chen, Yuanbo Pan, Mengxia Yan, Guanshui Bao, Xuhong Sun
Pages: 859-869
Published online on: 20 May 2020

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Article Open Access

Adiponectin inhibits cardiac arrest/cardiopulmonary resuscitation‑induced apoptosis in brain by increasing autophagy involved in AdipoR1‑AMPK signaling

Yarong He, Bofu Liu, Peng Yao, Yuming Shao, Yanwei  Cheng, Jie  Zhao, Jiang Wu, Zhi Wei Zhao, Wen Huang, Theodore   A. Christopher, Bernard Lopez, Xinliang Ma, Yu Cao
Pages: 870-878
Published online on: 22 May 2020

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Article Open Access

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

Jie Li, Chuanhua Gao, Shanshan Huang, Longteng Jin, Changzhong Jin
Pages: 879-885
Published online on: 18 May 2020

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Article Open Access

TIM‑3 inhibits PDGF‑BB‑induced atherogenic responses in human artery vascular smooth muscle cells

Chong Lian, Zhecun Wang, Jiacong Qiu, Baohong Jiang, Junbing Lv, Rongzhou He, Ruiming Liu, Wen Li, Jinsong Wang, Shenming Wang
Pages: 886-894
Published online on: 21 May 2020

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Article Open Access

Downregulation of miRNA‑328 promotes the angiogenesis of HUVECs by regulating the PIM1 and AKT/mTOR signaling pathway under high glucose and low serum condition

Yan Zou, Fei Wu, Qi Liu, Xian Deng, Rui Hai, Xuemei He, Xiangyu Zhou
Pages: 895-905
Published online on: 12 May 2020

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Article Open Access

Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma

Lingling Chen, Ming Wang, Zefeng Lin, Mengyu Yao, Wanshun Wang, Shi Cheng, Binglin Li, Yu Zhang, Qingshui Yin
Pages: 906-914
Published online on: 22 May 2020

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Article Open Access

Integrated microarray analysis to identify potential biomarkers and therapeutic targets in dilated cardiomyopathy

Hao Zhang, Junyu Huo, Wanying Jiang, Qijun Shan
Pages: 915-925
Published online on: 14 May 2020

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Article Open Access

miR‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth

Juan Peng, Jiang Jiang, Huizi Wang, Xinzi Feng, Xudong Dong
Pages: 926-938
Published online on: 22 May 2020

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Article Open Access

Targeting protein palmitoylation decreases palmitate‑induced sphere formation of human liver cancer cells

Lee‑Won Chong, Chia‑Ling Tsai, Kou‑Ching Yang, Chen‑Chung Liao, Yi‑Chao Hsu
Pages: 939-947
Published online on: 22 May 2020

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Article Open Access

High expression levels and localization of Sox5 in dilated cardiomyopathy

Yafeng Liu, Ben Jiang, Yide Cao, Wen Chen, Li Yin, Yueyue Xu, Zhibing Qiu
Pages: 948-956
Published online on: 22 May 2020

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Article Open Access

Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R

Yuanyuan Cui, Yuting Li, Jiayi Ning, Yajing Mi, Xiaolong  Wang, Zhongying Qiu, Le Li, Xingchun Gou
Pages: 957-963
Published online on: 18 May 2020

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Article Open Access

Protective effect of microRNA‑340‑5p against oxygen‑glucose deprivation/reperfusion in PC12 cells through targeting neuronal differentiation 4

Juan Wang, Ganzhe Liu
Pages: 964-974
Published online on: 22 May 2020

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Article Open Access

Comprehensive investigation of T and B cell receptor repertoires in an MC38 tumor model following murine anti‑PD‑1 administration

Lu Zhang, I‑Ming Wang, Nicolas Solban, Razvan Cristescu, Gefei Zeng, Brian Long
Pages: 975-985
Published online on: 22 May 2020

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Article Open Access

Drug screening and identification of key candidate genes and pathways of rheumatoid arthritis

Yu‑Quan Shi, Wu‑Fang Qi, Chun‑Yu Kong
Pages: 986-996
Published online on: 21 May 2020

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Article Open Access

Long non‑coding RNA‑based risk scoring system predicts prognosis of alcohol‑related hepatocellular carcinoma

Yue Luo, Jiaxiang Ye, Jiazhang Wei, Jinyan Zhang, Yongqiang Li
Pages: 997-1007
Published online on: 22 May 2020

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Article Open Access

MicroRNA‑29a promotes the neural differentiation of rat neural stem/progenitor cells by targeting KLF4

Yunan Gao, Hu Qiao, Tianyu Zhong, Zhen Lu, Yuxia Hou
Pages: 1008-1016
Published online on: 22 May 2020

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Article Open Access

TNF‑α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR‑335‑5p

Shanshan Li, Yixin Yin, Liping Yao, Ziyi Lin, Shengjun Sun, Jin Zhang, Xiaoyan Li
Pages: 1017-1025
Published online on: 18 May 2020

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Article Open Access

Saikosaponin D inhibits autophagosome‑lysosome fusion and induces autophagy‑independent apoptosis in MDA‑MB‑231 breast cancer cells

Ruoqiu Fu, Lin Zhang, Yuanyuan Li, Bin Li, Yue Ming, Zhiwei Li, Haiyan Xing, Jianhong Chen
Pages: 1026-1034
Published online on: 18 May 2020

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Article Open Access

Klotho downregulation contributes to myocardial damage of cardiorenal syndrome in sepsis

Fei Yan, Yue Feng, Jin Chen, Jing Yan
Pages: 1035-1043
Published online on: 22 May 2020

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Article Open Access

Comparison of neuronal death and expression of TNF‑α and MCT4 in the gerbil hippocampal CA1 region induced by ischemia/reperfusion under hyperthermia to those under normothermia

Taek Geun Ohk, Ji Hyeon Ahn, Young Eun Park, Tae‑Kyeong Lee, Bora Kim, Jae‑Chul Lee, Jun Hwi Cho, Joon Ha Park, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 1044-1052
Published online on: 22 May 2020

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Article

Integrated analysis of miRNA and mRNA expression in the blood of patients with Alzheimer's disease

Zongwen Wang, Lei Shen, Yue Wang, Shuqi Huang
Pages: 1053-1062
Published online on: 20 May 2020

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Article

Antihypertensive drug telmisartan inhibits cell proliferation of gastrointestinal stromal tumor cells in vitro

Hideki Kobara, Shintaro Fujihara, Hisakazu Iwama, Takanori Matsui, Ayako Fujimori, Taiga Chiyo, Shi Tingting, Nobuya Kobayashi, Noriko Nishiyama, Tatsuo Yachida, Tomoko Tadokoro, Kyoko Oura, Joji Tani, Koji Fujita, Takako Nomura, Hirohito Yoneyama, Asahiro Morishita, Keiichi Okano, Yasuyuki Suzuki, Hirohito Mori, Tsutomu Masaki
Pages: 1063-1071
Published online on: 14 May 2020

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Article

LncRNA GAS5 suppresses ER stress‑induced apoptosis and inflammation by regulating SERCA2b in HG‑treated retinal epithelial cell

Lei Jiang, Cun Wang, Xinyue Shen
Pages: 1072-1080
Published online on: 20 May 2020

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Article

Role of DNA damage in the progress of chronic tubule‑interstitial injury

Linxiao Sun, Xiandong Zhu, Jiao Luo, Cheng Wang, Bicheng Chen
Pages: 1081-1089
Published online on: 14 May 2020

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Correction Open Access

[Corrigendum] Protective effects of exendin‑4 on hypoxia/reoxygenation‑induced injury in H9c2 cells

Kai Lu, Guanglei Chang, Lin Ye, Peng Zhang, Yong Li, Dongying Zhang
Pages: 1090-1090
Published online on: 18 May 2020

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Review Open Access

Primary open angle glaucoma genetics: The common variants and their clinical associations (Review)

Alexandra Trivli, Maria I. Zervou, George N. Goulielmos, Demetrios A. Spandidos, Efstathios T. Detorakis
Pages: 1103-1110
Published online on: 09 June 2020

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Article Open Access

Identification of geraldol as an inhibitor of aquaporin‑4 binding by NMO‑IgG

Jie Wang, Shuai Wang, Meiyan Sun, Huijing Xu, Wei Liu, Deli Wang, Lei Zhang, Yan Li, Jiaming Cao, Fang Li, Miao Li
Pages: 1111-1118
Published online on: 04 June 2020

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Article Open Access

Cyclic stretch promotes the ossification of ligamentum flavum by modulating the Indian hedgehog signaling pathway

Rui Gao, Changgui Shi, Chengwei Yang, Yin Zhao, Xiongsheng Chen, Xuhui Zhou
Pages: 1119-1128
Published online on: 02 June 2020

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Article Open Access

Xanthan gum protects temporomandibular chondrocytes from IL‑1β through Pin1/NF‑κB signaling pathway

Fang Yuan, Jian‑Li Xie, Ke‑Yin Liu, Jian‑Liang Shan, Yu‑Gang Sun, Wang‑Gui Ying
Pages: 1129-1136
Published online on: 15 June 2020

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Article Open Access

Echinacoside promotes the proliferation of human renal tubular epithelial cells by blocking the HBX/TREM2‑mediated NF‑κB signalling pathway

Yufan Zhang, Qinfang Wu, Limin Zhong, Lei Wang, Dongwei Gong
Pages: 1137-1144
Published online on: 02 June 2020

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Article Open Access

Transcription box‑3 protects human umbilical vein endothelial cells in a high‑glucose environment through sirtuin 1/AKT signaling

Zhanjiang Yu, Wei Zhang, Xiankun Zhang, Donghui Xu, Na Wang
Pages: 1145-1154
Published online on: 15 June 2020

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Article Open Access

Identification of co‑expression modules and hub genes of retinoblastoma via co‑expression analysis and protein‑protein interaction networks

Yukun Mao, Qingbin Nie, Yang Yang, Gengsheng Mao
Pages: 1155-1168
Published online on: 27 May 2020

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Article Open Access

Superior CKIP-1 sensitivity of orofacial bone-derived mesenchymal stem cells in proliferation and osteogenic differentiation compared to long bone-derived mesenchymal stem cells

Xin Huang, Bingkun Cheng, Wen Song, Le Wang, Yanyuan Zhang, Yan Hou, Yu Song, Liang Kong
Pages: 1169-1178
Published online on: 15 June 2020

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Article Open Access

Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts

Lin Tao, Sichao Zhao, Zhengbo Tao, Kaicheng Wen, Siming Zhou, Wacili Da, Yue Zhu
Pages: 1179-1186
Published online on: 15 June 2020

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Article Open Access

TBOPP enhances the anticancer effect of cisplatin by inhibiting DOCK1 in renal cell carcinoma

Wei Zhang, Xiaoxiao Zheng, Shangzhi Xie, Shufen Zhang, Jiayan Mao, Ying Cai, Xuemei Lu, Wei Chen, Haibin Ni, Liping Xie
Pages: 1187-1194
Published online on: 16 June 2020

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Quantitative determination of human serum testosterone via isotope dilution ultra‑performance liquid chromatography tandem mass spectrometry

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[Corrigendum] Colony‑stimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferation

Fu Hua, Ye Tian, Yingchun Gao, Changhua Li, Xiaoping Liu
Pages: 1663-1663
Published online on: 29 May 2020

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June-2026 Volume 33 Issue 6

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[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
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RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

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Article Number: 170
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[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
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[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
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Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
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[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
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Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
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Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
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Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
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[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
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Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

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SCImago Journal Rank (SJR): 0.841

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Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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