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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2020 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review)

Saizhi Jiang, Jamie L. Young, Kai Wang, Yan Qian, Lu Cai
Pages: 603-611
Published online on: 22 May 2020

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Review

c‑Abl‑mediated tyrosine phosphorylation of DNA damage response proteins and implications in important cellular functions (Review)

Ameer Ali Bohio, Ruoxi Wang, Xianlu Zeng, Xueqing Ba
Pages: 612-619
Published online on: 18 May 2020

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Article Open Access

Identification of prognostic biomarkers and drug target prediction for colon cancer according to a competitive endogenous RNA network

Daojun Hu, Boke Zhang, Miao Yu, Wenjie Shi, Li Zhang
Pages: 620-632
Published online on: 22 May 2020

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Article Open Access

miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4

Yujing Fan, Kuanyu Wang
Pages: 633-642
Published online on: 18 May 2020

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Article Open Access

Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation

Ayano Tada, Haruyuki Nakayama‑Imaohji, Hisashi Yamasaki, Miad Elahi, Tamiko Nagao, Hirofumi Yagi, Masao Ishikawa, Koji Shibuya, Tomomi Kuwahara
Pages: 643-650
Published online on: 07 May 2020

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Article Open Access

TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats Corrigendum in /10.3892/mmr.2021.12144

Zhi‑Peng Lin, Hui‑Li Lin, Xue‑Ping Yu, Yi‑Juan Zheng, Si‑Yu Cheng
Pages: 651-660
Published online on: 07 May 2020

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Article Open Access

miR‑29 mediates exercise‑induced skeletal muscle angiogenesis by targeting VEGFA, COL4A1 and COL4A2 via the PI3K/Akt signaling pathway

Lei Chen, Jun Bai, Yanfei Li
Pages: 661-670
Published online on: 20 May 2020

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Article Open Access

Saccharomyces boulardii modulates necrotizing enterocolitis in neonatal mice by regulating the sirtuin 1/NF‑κB pathway and the intestinal microbiota

Kun Zhang, Xi Zhang, Anping Lv, Sainan Fan, Jinping Zhang
Pages: 671-680
Published online on: 07 May 2020

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Article Open Access

STAR mutations causing non‑classical lipoid adrenal hyperplasia manifested as familial glucocorticoid deficiency

Yuanyuan Luo, Ruojing Bai, Zhifang Wang, Xiaofan Zhu, Jingjing Xing, Xialian Li
Pages: 681-686
Published online on: 07 May 2020

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Article Open Access

Long non‑coding RNA NNT‑AS1 knockdown represses the progression of gastric cancer via modulating the miR‑142‑5p/SOX4/Wnt/β‑catenin signaling pathway

Jianfeng Zhang, Kai Zhang, Yingkui Hou
Pages: 687-696
Published online on: 18 May 2020

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Article Open Access

Anticancer effect of caudatin in diethylnitrosamine‑induced hepatocarcinogenesis in rats

Jie Song, Wenbo Ding, Bojia Liu, Dan Liu, Zhi Xia, Li Zhang, Li Cui, Yi Luo, Xiaobin Jia, Liang Feng
Pages: 697-706
Published online on: 07 May 2020

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Article Open Access

Effects of dihydroartemisinin on the gut microbiome of mice

Yanyan Liu, Yanhong Yang, Yuting Lei, Lanxiang Yang, Xueying Zhang, Jian Yuan, Zili Lei
Pages: 707-714
Published online on: 20 May 2020

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Article Open Access

Effects of human umbilical cord mesenchymal stem cells derived from exosomes on migration ability of endometrial glandular epithelial cells

Ying Feng, Fuliang Zhan, Yanying Zhong, Buzhen Tan
Pages: 715-722
Published online on: 07 May 2020

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Article Open Access

Long non‑coding RNA FLVCR1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑30b‑3p

Weida Gao, Hongbin Li, Yang Liu, Yao Zhang, Hong Zhao, Fei Liu
Pages: 723-732
Published online on: 15 May 2020

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Article Open Access

Syntenin regulates melanogenesis via the p38 MAPK pathway

Lijun Sun, Chunyan Guo, Liting Yan, Huijin Li, Jingying Sun, Xueping Huo, Xin Xie, Jun Hu
Pages: 733-738
Published online on: 07 May 2020

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Article Open Access

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model

Weigang Cui, Chunli Sun, Yuqi Ma, Songtao Wang, Xianwei Wang, Yinghua Zhang
Pages: 739-750
Published online on: 18 May 2020

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Article Open Access

Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture

Zhidong Zhou, Hejian Li, Hongchun Li, Jing Zhang, Kaiwen Fu, Cao Cao, Fumou Deng, Jun Luo
Pages: 751-762
Published online on: 20 May 2020

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Article Open Access

Effects of sacral nerve electrical stimulation on 5‑HT and 5‑HT3AR/5‑HT4R levels in the colon and sacral cord of acute spinal cord injury rat models

Yi Zhu, Jie Cheng, Jichao Yin, Yujie Yang, Jiabao Guo, Wenyi  Zhang, Bing Xie, Haixia Lu, Dingjun Hao
Pages: 763-773
Published online on: 15 May 2020

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Article Open Access

NCTD elicits proapoptotic and antiglycolytic effects on colorectal cancer cells via modulation of Fam46c expression and inhibition of ERK1/2 signaling Retraction in /10.3892/mmr.2023.13078

Shiqiang Zhang, Yun Yang, Yunwei Hua, Chen Hu, Yi Zhong
Pages: 774-782
Published online on: 18 May 2020

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Article Open Access

Downregulation of microRNA‑106a‑5p alleviates ox‑LDL‑mediated endothelial cell injury by targeting STAT3

Ying Hu, Rong Xu, Yue He, Zhibo Zhao, Xudong Mao, Ling Lin, Jun Hu
Pages: 783-791
Published online on: 14 May 2020

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Article Open Access

Circulating mRNA and microRNA profiling analysis in patients with ischemic stroke

Sujuan Sun, Litao Li, Lipeng Dong, Jinming Cheng, Congying Zhao, Chu Bao, Hebo Wang
Pages: 792-802
Published online on: 14 May 2020

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Article Open Access

Effects of miR‑195‑5p on cell proliferation and apoptosis in gestational diabetes mellitus via targeting EZH2

Xiaojie Liao, Zhuolin Zhou, Xiaoliu Zhang
Pages: 803-809
Published online on: 12 May 2020

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Article Open Access

Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells

Qiong Wang, Wenwen Zhu, Geqiong Xiao, Mengyu Ding, Jian Chang, Hui Liao
Pages: 810-818
Published online on: 22 May 2020

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Article Open Access

Expression and clinical value of SALL4 in renal cell carcinomas

Jianping Che, Pengfei Wu, Guangchun Wang, Xudong Yao, Junhua Zheng, Changcheng Guo
Pages: 819-827
Published online on: 22 May 2020

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Article Open Access

Clinical characteristics and prognostic significance of TCGA and ACRG classification in gastric cancer among the Chinese population

Qiang Wang, Qi Xie, Yang Liu, Honghai Guo, Yingchun Ren, Jianke Li, Qun Zhao
Pages: 828-840
Published online on: 22 May 2020

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Article Open Access

Downregulated miR‑29a promotes B cell overactivation by upregulating Crk‑like protein in systemic lupus erythematosus

Xinyu Shi, Lulu Ye, Shuqi Xu, Gangqiang Guo, Ziyi Zuo, Mengke Ye, Lejiang Zhu, Baoqing Li, Xiangyang Xue, Qiaoai Lin, Xiaokai Ding
Pages: 841-849
Published online on: 21 May 2020

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Article Open Access

miR‑217‑5p regulates myogenesis in skeletal muscle stem cells by targeting FGFR2

Menghai Zhu, Gang Chen, Yi Yang, Jiantao Yang, Bengang Qin, Liqiang Gu
Pages: 850-858
Published online on: 07 May 2020

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Article Open Access

Identification of potential crucial genes and molecular mechanisms in glioblastoma multiforme by bioinformatics analysis

Xiaojie Chen, Yuanbo Pan, Mengxia Yan, Guanshui Bao, Xuhong Sun
Pages: 859-869
Published online on: 20 May 2020

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Article Open Access

Adiponectin inhibits cardiac arrest/cardiopulmonary resuscitation‑induced apoptosis in brain by increasing autophagy involved in AdipoR1‑AMPK signaling

Yarong He, Bofu Liu, Peng Yao, Yuming Shao, Yanwei  Cheng, Jie  Zhao, Jiang Wu, Zhi Wei Zhao, Wen Huang, Theodore   A. Christopher, Bernard Lopez, Xinliang Ma, Yu Cao
Pages: 870-878
Published online on: 22 May 2020

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Article Open Access

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

Jie Li, Chuanhua Gao, Shanshan Huang, Longteng Jin, Changzhong Jin
Pages: 879-885
Published online on: 18 May 2020

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Article Open Access

TIM‑3 inhibits PDGF‑BB‑induced atherogenic responses in human artery vascular smooth muscle cells

Chong Lian, Zhecun Wang, Jiacong Qiu, Baohong Jiang, Junbing Lv, Rongzhou He, Ruiming Liu, Wen Li, Jinsong Wang, Shenming Wang
Pages: 886-894
Published online on: 21 May 2020

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Article Open Access

Downregulation of miRNA‑328 promotes the angiogenesis of HUVECs by regulating the PIM1 and AKT/mTOR signaling pathway under high glucose and low serum condition

Yan Zou, Fei Wu, Qi Liu, Xian Deng, Rui Hai, Xuemei He, Xiangyu Zhou
Pages: 895-905
Published online on: 12 May 2020

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Article Open Access

Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma

Lingling Chen, Ming Wang, Zefeng Lin, Mengyu Yao, Wanshun Wang, Shi Cheng, Binglin Li, Yu Zhang, Qingshui Yin
Pages: 906-914
Published online on: 22 May 2020

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Article Open Access

Integrated microarray analysis to identify potential biomarkers and therapeutic targets in dilated cardiomyopathy

Hao Zhang, Junyu Huo, Wanying Jiang, Qijun Shan
Pages: 915-925
Published online on: 14 May 2020

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Article Open Access

miR‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth

Juan Peng, Jiang Jiang, Huizi Wang, Xinzi Feng, Xudong Dong
Pages: 926-938
Published online on: 22 May 2020

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Article Open Access

Targeting protein palmitoylation decreases palmitate‑induced sphere formation of human liver cancer cells

Lee‑Won Chong, Chia‑Ling Tsai, Kou‑Ching Yang, Chen‑Chung Liao, Yi‑Chao Hsu
Pages: 939-947
Published online on: 22 May 2020

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Article Open Access

High expression levels and localization of Sox5 in dilated cardiomyopathy

Yafeng Liu, Ben Jiang, Yide Cao, Wen Chen, Li Yin, Yueyue Xu, Zhibing Qiu
Pages: 948-956
Published online on: 22 May 2020

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Article Open Access

Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R

Yuanyuan Cui, Yuting Li, Jiayi Ning, Yajing Mi, Xiaolong  Wang, Zhongying Qiu, Le Li, Xingchun Gou
Pages: 957-963
Published online on: 18 May 2020

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Article Open Access

Protective effect of microRNA‑340‑5p against oxygen‑glucose deprivation/reperfusion in PC12 cells through targeting neuronal differentiation 4

Juan Wang, Ganzhe Liu
Pages: 964-974
Published online on: 22 May 2020

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Article Open Access

Comprehensive investigation of T and B cell receptor repertoires in an MC38 tumor model following murine anti‑PD‑1 administration

Lu Zhang, I‑Ming Wang, Nicolas Solban, Razvan Cristescu, Gefei Zeng, Brian Long
Pages: 975-985
Published online on: 22 May 2020

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Article Open Access

Drug screening and identification of key candidate genes and pathways of rheumatoid arthritis

Yu‑Quan Shi, Wu‑Fang Qi, Chun‑Yu Kong
Pages: 986-996
Published online on: 21 May 2020

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Article Open Access

Long non‑coding RNA‑based risk scoring system predicts prognosis of alcohol‑related hepatocellular carcinoma

Yue Luo, Jiaxiang Ye, Jiazhang Wei, Jinyan Zhang, Yongqiang Li
Pages: 997-1007
Published online on: 22 May 2020

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Article Open Access

MicroRNA‑29a promotes the neural differentiation of rat neural stem/progenitor cells by targeting KLF4

Yunan Gao, Hu Qiao, Tianyu Zhong, Zhen Lu, Yuxia Hou
Pages: 1008-1016
Published online on: 22 May 2020

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Article Open Access

TNF‑α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR‑335‑5p

Shanshan Li, Yixin Yin, Liping Yao, Ziyi Lin, Shengjun Sun, Jin Zhang, Xiaoyan Li
Pages: 1017-1025
Published online on: 18 May 2020

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Article Open Access

Saikosaponin D inhibits autophagosome‑lysosome fusion and induces autophagy‑independent apoptosis in MDA‑MB‑231 breast cancer cells

Ruoqiu Fu, Lin Zhang, Yuanyuan Li, Bin Li, Yue Ming, Zhiwei Li, Haiyan Xing, Jianhong Chen
Pages: 1026-1034
Published online on: 18 May 2020

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Article Open Access

Klotho downregulation contributes to myocardial damage of cardiorenal syndrome in sepsis

Fei Yan, Yue Feng, Jin Chen, Jing Yan
Pages: 1035-1043
Published online on: 22 May 2020

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Article Open Access

Comparison of neuronal death and expression of TNF‑α and MCT4 in the gerbil hippocampal CA1 region induced by ischemia/reperfusion under hyperthermia to those under normothermia

Taek Geun Ohk, Ji Hyeon Ahn, Young Eun Park, Tae‑Kyeong Lee, Bora Kim, Jae‑Chul Lee, Jun Hwi Cho, Joon Ha Park, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 1044-1052
Published online on: 22 May 2020

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Article

Integrated analysis of miRNA and mRNA expression in the blood of patients with Alzheimer's disease

Zongwen Wang, Lei Shen, Yue Wang, Shuqi Huang
Pages: 1053-1062
Published online on: 20 May 2020

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Article

Antihypertensive drug telmisartan inhibits cell proliferation of gastrointestinal stromal tumor cells in vitro

Hideki Kobara, Shintaro Fujihara, Hisakazu Iwama, Takanori Matsui, Ayako Fujimori, Taiga Chiyo, Shi Tingting, Nobuya Kobayashi, Noriko Nishiyama, Tatsuo Yachida, Tomoko Tadokoro, Kyoko Oura, Joji Tani, Koji Fujita, Takako Nomura, Hirohito Yoneyama, Asahiro Morishita, Keiichi Okano, Yasuyuki Suzuki, Hirohito Mori, Tsutomu Masaki
Pages: 1063-1071
Published online on: 14 May 2020

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Article

LncRNA GAS5 suppresses ER stress‑induced apoptosis and inflammation by regulating SERCA2b in HG‑treated retinal epithelial cell

Lei Jiang, Cun Wang, Xinyue Shen
Pages: 1072-1080
Published online on: 20 May 2020

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Article

Role of DNA damage in the progress of chronic tubule‑interstitial injury

Linxiao Sun, Xiandong Zhu, Jiao Luo, Cheng Wang, Bicheng Chen
Pages: 1081-1089
Published online on: 14 May 2020

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Correction Open Access

[Corrigendum] Protective effects of exendin‑4 on hypoxia/reoxygenation‑induced injury in H9c2 cells

Kai Lu, Guanglei Chang, Lin Ye, Peng Zhang, Yong Li, Dongying Zhang
Pages: 1090-1090
Published online on: 18 May 2020

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Review Open Access

Primary open angle glaucoma genetics: The common variants and their clinical associations (Review)

Alexandra Trivli, Maria I. Zervou, George N. Goulielmos, Demetrios A. Spandidos, Efstathios T. Detorakis
Pages: 1103-1110
Published online on: 09 June 2020

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Article Open Access

Identification of geraldol as an inhibitor of aquaporin‑4 binding by NMO‑IgG

Jie Wang, Shuai Wang, Meiyan Sun, Huijing Xu, Wei Liu, Deli Wang, Lei Zhang, Yan Li, Jiaming Cao, Fang Li, Miao Li
Pages: 1111-1118
Published online on: 04 June 2020

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Article Open Access

Cyclic stretch promotes the ossification of ligamentum flavum by modulating the Indian hedgehog signaling pathway

Rui Gao, Changgui Shi, Chengwei Yang, Yin Zhao, Xiongsheng Chen, Xuhui Zhou
Pages: 1119-1128
Published online on: 02 June 2020

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Article Open Access

Xanthan gum protects temporomandibular chondrocytes from IL‑1β through Pin1/NF‑κB signaling pathway

Fang Yuan, Jian‑Li Xie, Ke‑Yin Liu, Jian‑Liang Shan, Yu‑Gang Sun, Wang‑Gui Ying
Pages: 1129-1136
Published online on: 15 June 2020

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Article Open Access

Echinacoside promotes the proliferation of human renal tubular epithelial cells by blocking the HBX/TREM2‑mediated NF‑κB signalling pathway

Yufan Zhang, Qinfang Wu, Limin Zhong, Lei Wang, Dongwei Gong
Pages: 1137-1144
Published online on: 02 June 2020

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Article Open Access

Transcription box‑3 protects human umbilical vein endothelial cells in a high‑glucose environment through sirtuin 1/AKT signaling

Zhanjiang Yu, Wei Zhang, Xiankun Zhang, Donghui Xu, Na Wang
Pages: 1145-1154
Published online on: 15 June 2020

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Article Open Access

Identification of co‑expression modules and hub genes of retinoblastoma via co‑expression analysis and protein‑protein interaction networks

Yukun Mao, Qingbin Nie, Yang Yang, Gengsheng Mao
Pages: 1155-1168
Published online on: 27 May 2020

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Article Open Access

Superior CKIP-1 sensitivity of orofacial bone-derived mesenchymal stem cells in proliferation and osteogenic differentiation compared to long bone-derived mesenchymal stem cells

Xin Huang, Bingkun Cheng, Wen Song, Le Wang, Yanyuan Zhang, Yan Hou, Yu Song, Liang Kong
Pages: 1169-1178
Published online on: 15 June 2020

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Article Open Access

Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts

Lin Tao, Sichao Zhao, Zhengbo Tao, Kaicheng Wen, Siming Zhou, Wacili Da, Yue Zhu
Pages: 1179-1186
Published online on: 15 June 2020

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Article Open Access

TBOPP enhances the anticancer effect of cisplatin by inhibiting DOCK1 in renal cell carcinoma

Wei Zhang, Xiaoxiao Zheng, Shangzhi Xie, Shufen Zhang, Jiayan Mao, Ying Cai, Xuemei Lu, Wei Chen, Haibin Ni, Liping Xie
Pages: 1187-1194
Published online on: 16 June 2020

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Knockdown of long non‑coding RNA AK094629 attenuates the interleukin‑1β induced expression of interleukin‑6 in synovium‑derived mesenchymal stem cells from the temporomandibular joint

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Bioinformatics analysis of small RNAs in Helicobacter pylori and the role of NAT‑67 under tinidazole treatment

Jie Du, Wang Zhang, Xiao‑Hui Li, Yuan‑Jian Li
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Angiopoietin-2 regulated by progesterone induces uterine vascular remodeling during pregnancy

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Quantitative proteomic characterization of microvesicles/exosomes from the cerebrospinal fluid of patients with acute bilirubin encephalopathy

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Detection of chromosomal abnormalities in spontaneous miscarriage by low‑coverage next‑generation sequencing

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MicroRNA-196a promotes cell proliferation and inhibits apoptosis in human ovarian cancer by directly targeting DDX3 and regulating the PTEN/PI3K/AKT signaling pathway

Jie Ni, Li Chen, Li Ling, Mengfei Wu, Qiongzhen Ren, Weipei Zhu
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A novel variant in AIRE causing a rare, non‑classical autoimmune polyendocrine syndrome type 1

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Overexpression of ATG4a promotes autophagy and proliferation, and inhibits apoptosis in lens epithelial cells via the AMPK and Akt pathways

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Long non-coding RNA expression profiling following treatment with resveratrol to improve insulin resistance

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Age‑dependent alterations in the immunoreactivity of macrophage inflammatory protein‑3α and its receptor CCR6 in the gerbil hippocampus

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Salvianolic acid B attenuates renal interstitial fibrosis by regulating the HPSE/SDC1 axis

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Diosmetin alleviates hypoxia‑induced myocardial apoptosis by inducing autophagy through AMPK activation

Qijun Si, Yujie Shi, Dandan Huang, Na Zhang
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Troxerutin attenuates oxygen‑glucose deprivation and reoxygenation‑induced oxidative stress and inflammation by enhancing the PI3K/AKT/HIF‑1α signaling pathway in H9C2 cardiomyocytes

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Bioinformatic analysis of the potential molecular mechanism of PAK7 expression in glioblastoma

Xuefeng Wang, Shuang Liu, Zhengkai Shao, Penghai Zhang
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RP105 plays a cardioprotective role in myocardial ischemia reperfusion injury by regulating the Toll‑like receptor 2/4 signaling pathways

Weiling Huang, Jian Yang, Chao He, Jun Yang
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Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1 Retraction in /10.3892/mmr.2025.13718

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Effects of an ethyl acetate extract of Daphne altaica stem bark on the cell cycle, apoptosis and expression of PPARγ in Eca‑109 human esophageal carcinoma cells

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The gonadal expression pattern of lipocalin‑2 and 24p3 receptor is modified in the gonads of the offspring of obese rats

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Role of endoplasmic reticulum oxidase 1α in H9C2 cardiomyocytes following hypoxia/reoxygenation injury

Lina Lai, Yue Liu, Yuanyuan Liu, Ni Zhang, Shilu Cao, Xiaojing Zhang, Di Wu
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Schizophrenia‑associated microRNA‑148b‑3p regulates COMT and PRSS16 expression by targeting the ZNF804A gene in human neuroblastoma cells

Shanshan Wu, Pengjie Wang, Ran Tao, Pengbo Yang, Xiaorui Yu, Ye Li, Qiuya Shao, Fayi Nie, Jing Ha, Rui Zhang, Ye Tian, Jie Ma
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TAK‑242 exerts a neuroprotective effect via suppression of the TLR4/MyD88/TRIF/NF‑κB signaling pathway in a neonatal hypoxic‑ischemic encephalopathy rat model

Lijun Jiang, Zhenxing Xu, Hui Li, Mingfu Wu, Fudong Wang, Shunying Liu, Jianlan Tao, Xing Feng
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lncRNA MALAT1 modulates cancer stem cell properties of liver cancer cells by regulating YAP1 expression via miR‑375 sponging

Liying Zhao, Guohua Lou, Aichun Li, Yanning Liu
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Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats

Wen Yuan, Heng‑Ya Song, Jie Xiong, Wan‑Li Jiang, Gan‑Jun Kang, Jie Huang, Song‑Ping Xie
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Cytoprotective role of humanin in lens epithelial cell oxidative stress‑induced injury

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miR‑320‑3p is involved in morphine pre‑conditioning to protect rat cardiomyocytes from ischemia/reperfusion injury through targeting Akt3

Lan Cao, Shijun Chai
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Long non-coding RNA ANRIL knockdown suppresses apoptosis and pro-inflammatory cytokines while enhancing neurite outgrowth via binding microRNA-125a in a cellular model of Alzheimer's disease Retraction in /10.3892/mmr.2025.13772

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Association between levels of aquaporin 3 in the placenta and adiponectin in the umbilical cord blood with gestational diabetes mellitus and pregnancy outcome

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Propofol‑induced miR‑125a‑5p inhibits the proliferation and metastasis of ovarian cancer by suppressing LIN28B

Juan Zeng, Yu‑Kun Li, Fei‑Fei Quan, Xin Zeng, Chang‑Ye Chen, Tian Zeng, Juan Zou, Wen‑Juan Tong
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Transcriptomic changes involved in the dedifferentiation of myofibroblasts derived from the lung of a patient with idiopathic pulmonary fibrosis

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Tubeimoside‑1 induces apoptosis in human glioma U251 cells by suppressing PI3K/Akt‑mediated signaling pathways

Li‑Juan Cao, Hai‑Tang Xie, Zhong‑Xia Chu, Yue Ma, Ming‑Ming Wang, Zhuang Shi
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Deficiency of PDK1 in osteoclasts delays fracture healing and repair

Dongliang Xiao, Quan Zhou, Yiguang Bai, Baichuan Cao, Qiong Zhang, Gaofeng Zeng, Shaohui Zong
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Non‑invasive prenatal diagnosis of thalassemia through multiplex PCR, target capture and next‑generation sequencing

Xu Yang, Yanchou Ye, Dongmei Fan, Sheng Lin, Ming Li, Hongying Hou, Jun Zhang, Xuexi Yang
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Siva‑1 regulates multidrug resistance of gastric cancer by targeting MDR1 and MRP1 via the NF‑κB pathway

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Key miRNAs associated with memory and learning disorder upon exposure to sevoflurane determined by RNA sequencing

Huaqin Sun, Hongyi Hu, Xiaoping Xu, Tao Tao, Zhehao Liang
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Quantitative determination of human serum testosterone via isotope dilution ultra‑performance liquid chromatography tandem mass spectrometry

Guang Sun, Jinmei Xue, Liuxu Li, Xue Li, Yaqiong  Cui, Bin Qiao, Dianjun Wei, Huiqiang Li
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Cholestatic models induced by lithocholic acid and α‑naphthylisothiocyanate: Different etiological mechanisms for liver injury but shared JNK/STAT3 signaling

Gangming Xu, Manyun Dai, Xiuting Zheng, Hante Lin, Aiming Liu, Julin Yang
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miR‑192‑5p upregulation mediates the suppression of curcumin in human NSCLC cell proliferation, migration and invasion by targeting c‑Myc and inactivating the Wnt/β‑catenin signaling pathway

Yancheng Pan, Ying Sun, Ziqi Liu, Chao Zhang
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miR‑200c‑3p regulates the proliferation and apoptosis of human trabecular meshwork cells by targeting PTEN

Yifei Shen, Yin Zhu, Fei Rong
Pages: 1605-1612
Published online on: 01 June 2020

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MicroRNA‑34a inhibits the proliferation and promotes the chemosensitivity of retinoblastoma cells by downregulating Notch1 expression

Weiwei Yin, Feifei Gao, Suotao Zhang
Pages: 1613-1620
Published online on: 15 June 2020

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MicroRNA‑133b aggravates atherosclerosis by activating the Notch signaling pathway

Baizhi Han, Tao Li, Shiliang Zheng
Pages: 1621-1630
Published online on: 11 June 2020

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Downregulation of folate receptor α contributes to homocysteine‑induced human umbilical vein endothelial cell injury via activation of endoplasmic reticulum stress

Jie Cui, Cheng Cao, Huan Hu, Hao Zhang, Yujing Yang, Luqiao Wang, Xiao Huang, Ping Li
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Transcription factor AP‑2α negatively regulates thymic stromal lymphopoietin expression in respiratory syncytial virus infection

Jia He, Qian Cao, Dan‑Dan Feng, Jia‑He Chen, Guo‑Ping Zhou
Pages: 1639-1646
Published online on: 28 May 2020

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Melatonin inhibits the endoplasmic reticulum stress‑induced, C/EBP homologous protein‑mediated pathway in acute pancreatitis

Qian Zhao, Hui Zhang, Jie Wu, Xiangyin Lv, Xianghong Jin, Jianwen Hu
Pages: 1647-1655
Published online on: 10 June 2020

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SB203580 protects against inflammatory response and lung injury in a mouse model of lipopolysaccharide‑induced acute lung injury

Guirong Li, Youai Dai, Jianxin Tan, Jian Zou, Xiaowei Nie, Zhenkun Yang, Jingjing Zhao, Xusheng Yang, Jingyu Chen
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Published online on: 04 June 2020

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Correction Open Access

[Corrigendum] Colony‑stimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferation

Fu Hua, Ye Tian, Yingchun Gao, Changhua Li, Xiaoping Liu
Pages: 1663-1663
Published online on: 29 May 2020

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March-2026 Volume 33 Issue 3

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CiteScore: 8.5

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CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

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Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
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[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
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PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
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[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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April-2026 Volume 33 Issue 4

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CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
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Published online on: 04 February 2026

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Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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