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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2020 Volume 22 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review)

Saizhi Jiang, Jamie L. Young, Kai Wang, Yan Qian, Lu Cai
Pages: 603-611
Published online on: 22 May 2020

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Review

c‑Abl‑mediated tyrosine phosphorylation of DNA damage response proteins and implications in important cellular functions (Review)

Ameer Ali Bohio, Ruoxi Wang, Xianlu Zeng, Xueqing Ba
Pages: 612-619
Published online on: 18 May 2020

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Article Open Access

Identification of prognostic biomarkers and drug target prediction for colon cancer according to a competitive endogenous RNA network

Daojun Hu, Boke Zhang, Miao Yu, Wenjie Shi, Li Zhang
Pages: 620-632
Published online on: 22 May 2020

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Article Open Access

miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4

Yujing Fan, Kuanyu Wang
Pages: 633-642
Published online on: 18 May 2020

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Article Open Access

Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation

Ayano Tada, Haruyuki Nakayama‑Imaohji, Hisashi Yamasaki, Miad Elahi, Tamiko Nagao, Hirofumi Yagi, Masao Ishikawa, Koji Shibuya, Tomomi Kuwahara
Pages: 643-650
Published online on: 07 May 2020

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Article Open Access

TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats Corrigendum in /10.3892/mmr.2021.12144

Zhi‑Peng Lin, Hui‑Li Lin, Xue‑Ping Yu, Yi‑Juan Zheng, Si‑Yu Cheng
Pages: 651-660
Published online on: 07 May 2020

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Article Open Access

miR‑29 mediates exercise‑induced skeletal muscle angiogenesis by targeting VEGFA, COL4A1 and COL4A2 via the PI3K/Akt signaling pathway

Lei Chen, Jun Bai, Yanfei Li
Pages: 661-670
Published online on: 20 May 2020

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Article Open Access

Saccharomyces boulardii modulates necrotizing enterocolitis in neonatal mice by regulating the sirtuin 1/NF‑κB pathway and the intestinal microbiota

Kun Zhang, Xi Zhang, Anping Lv, Sainan Fan, Jinping Zhang
Pages: 671-680
Published online on: 07 May 2020

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Article Open Access

STAR mutations causing non‑classical lipoid adrenal hyperplasia manifested as familial glucocorticoid deficiency

Yuanyuan Luo, Ruojing Bai, Zhifang Wang, Xiaofan Zhu, Jingjing Xing, Xialian Li
Pages: 681-686
Published online on: 07 May 2020

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Article Open Access

Long non‑coding RNA NNT‑AS1 knockdown represses the progression of gastric cancer via modulating the miR‑142‑5p/SOX4/Wnt/β‑catenin signaling pathway

Jianfeng Zhang, Kai Zhang, Yingkui Hou
Pages: 687-696
Published online on: 18 May 2020

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Article Open Access

Anticancer effect of caudatin in diethylnitrosamine‑induced hepatocarcinogenesis in rats

Jie Song, Wenbo Ding, Bojia Liu, Dan Liu, Zhi Xia, Li Zhang, Li Cui, Yi Luo, Xiaobin Jia, Liang Feng
Pages: 697-706
Published online on: 07 May 2020

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Article Open Access

Effects of dihydroartemisinin on the gut microbiome of mice

Yanyan Liu, Yanhong Yang, Yuting Lei, Lanxiang Yang, Xueying Zhang, Jian Yuan, Zili Lei
Pages: 707-714
Published online on: 20 May 2020

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Article Open Access

Effects of human umbilical cord mesenchymal stem cells derived from exosomes on migration ability of endometrial glandular epithelial cells

Ying Feng, Fuliang Zhan, Yanying Zhong, Buzhen Tan
Pages: 715-722
Published online on: 07 May 2020

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Article Open Access

Long non‑coding RNA FLVCR1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑30b‑3p

Weida Gao, Hongbin Li, Yang Liu, Yao Zhang, Hong Zhao, Fei Liu
Pages: 723-732
Published online on: 15 May 2020

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Article Open Access

Syntenin regulates melanogenesis via the p38 MAPK pathway

Lijun Sun, Chunyan Guo, Liting Yan, Huijin Li, Jingying Sun, Xueping Huo, Xin Xie, Jun Hu
Pages: 733-738
Published online on: 07 May 2020

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Article Open Access

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model

Weigang Cui, Chunli Sun, Yuqi Ma, Songtao Wang, Xianwei Wang, Yinghua Zhang
Pages: 739-750
Published online on: 18 May 2020

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Article Open Access

Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture

Zhidong Zhou, Hejian Li, Hongchun Li, Jing Zhang, Kaiwen Fu, Cao Cao, Fumou Deng, Jun Luo
Pages: 751-762
Published online on: 20 May 2020

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Article Open Access

Effects of sacral nerve electrical stimulation on 5‑HT and 5‑HT3AR/5‑HT4R levels in the colon and sacral cord of acute spinal cord injury rat models

Yi Zhu, Jie Cheng, Jichao Yin, Yujie Yang, Jiabao Guo, Wenyi  Zhang, Bing Xie, Haixia Lu, Dingjun Hao
Pages: 763-773
Published online on: 15 May 2020

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Article Open Access

NCTD elicits proapoptotic and antiglycolytic effects on colorectal cancer cells via modulation of Fam46c expression and inhibition of ERK1/2 signaling Retraction in /10.3892/mmr.2023.13078

Shiqiang Zhang, Yun Yang, Yunwei Hua, Chen Hu, Yi Zhong
Pages: 774-782
Published online on: 18 May 2020

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Article Open Access

Downregulation of microRNA‑106a‑5p alleviates ox‑LDL‑mediated endothelial cell injury by targeting STAT3

Ying Hu, Rong Xu, Yue He, Zhibo Zhao, Xudong Mao, Ling Lin, Jun Hu
Pages: 783-791
Published online on: 14 May 2020

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Article Open Access

Circulating mRNA and microRNA profiling analysis in patients with ischemic stroke

Sujuan Sun, Litao Li, Lipeng Dong, Jinming Cheng, Congying Zhao, Chu Bao, Hebo Wang
Pages: 792-802
Published online on: 14 May 2020

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Article Open Access

Effects of miR‑195‑5p on cell proliferation and apoptosis in gestational diabetes mellitus via targeting EZH2

Xiaojie Liao, Zhuolin Zhou, Xiaoliu Zhang
Pages: 803-809
Published online on: 12 May 2020

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Article Open Access

Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells

Qiong Wang, Wenwen Zhu, Geqiong Xiao, Mengyu Ding, Jian Chang, Hui Liao
Pages: 810-818
Published online on: 22 May 2020

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Article Open Access

Expression and clinical value of SALL4 in renal cell carcinomas

Jianping Che, Pengfei Wu, Guangchun Wang, Xudong Yao, Junhua Zheng, Changcheng Guo
Pages: 819-827
Published online on: 22 May 2020

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Article Open Access

Clinical characteristics and prognostic significance of TCGA and ACRG classification in gastric cancer among the Chinese population

Qiang Wang, Qi Xie, Yang Liu, Honghai Guo, Yingchun Ren, Jianke Li, Qun Zhao
Pages: 828-840
Published online on: 22 May 2020

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Article Open Access

Downregulated miR‑29a promotes B cell overactivation by upregulating Crk‑like protein in systemic lupus erythematosus

Xinyu Shi, Lulu Ye, Shuqi Xu, Gangqiang Guo, Ziyi Zuo, Mengke Ye, Lejiang Zhu, Baoqing Li, Xiangyang Xue, Qiaoai Lin, Xiaokai Ding
Pages: 841-849
Published online on: 21 May 2020

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Article Open Access

miR‑217‑5p regulates myogenesis in skeletal muscle stem cells by targeting FGFR2

Menghai Zhu, Gang Chen, Yi Yang, Jiantao Yang, Bengang Qin, Liqiang Gu
Pages: 850-858
Published online on: 07 May 2020

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Article Open Access

Identification of potential crucial genes and molecular mechanisms in glioblastoma multiforme by bioinformatics analysis

Xiaojie Chen, Yuanbo Pan, Mengxia Yan, Guanshui Bao, Xuhong Sun
Pages: 859-869
Published online on: 20 May 2020

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Article Open Access

Adiponectin inhibits cardiac arrest/cardiopulmonary resuscitation‑induced apoptosis in brain by increasing autophagy involved in AdipoR1‑AMPK signaling

Yarong He, Bofu Liu, Peng Yao, Yuming Shao, Yanwei  Cheng, Jie  Zhao, Jiang Wu, Zhi Wei Zhao, Wen Huang, Theodore   A. Christopher, Bernard Lopez, Xinliang Ma, Yu Cao
Pages: 870-878
Published online on: 22 May 2020

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Article Open Access

SAMHD1 expression is associated with low immune activation but not correlated with HIV‑1 DNA levels in CD4+ T cells of patients with HIV‑1

Jie Li, Chuanhua Gao, Shanshan Huang, Longteng Jin, Changzhong Jin
Pages: 879-885
Published online on: 18 May 2020

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Article Open Access

TIM‑3 inhibits PDGF‑BB‑induced atherogenic responses in human artery vascular smooth muscle cells

Chong Lian, Zhecun Wang, Jiacong Qiu, Baohong Jiang, Junbing Lv, Rongzhou He, Ruiming Liu, Wen Li, Jinsong Wang, Shenming Wang
Pages: 886-894
Published online on: 21 May 2020

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Article Open Access

Downregulation of miRNA‑328 promotes the angiogenesis of HUVECs by regulating the PIM1 and AKT/mTOR signaling pathway under high glucose and low serum condition

Yan Zou, Fei Wu, Qi Liu, Xian Deng, Rui Hai, Xuemei He, Xiangyu Zhou
Pages: 895-905
Published online on: 12 May 2020

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Article Open Access

Mild microwave ablation combined with HSP90 and TGF‑β1 inhibitors enhances the therapeutic effect on osteosarcoma

Lingling Chen, Ming Wang, Zefeng Lin, Mengyu Yao, Wanshun Wang, Shi Cheng, Binglin Li, Yu Zhang, Qingshui Yin
Pages: 906-914
Published online on: 22 May 2020

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Article Open Access

Integrated microarray analysis to identify potential biomarkers and therapeutic targets in dilated cardiomyopathy

Hao Zhang, Junyu Huo, Wanying Jiang, Qijun Shan
Pages: 915-925
Published online on: 14 May 2020

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Article Open Access

miR‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth

Juan Peng, Jiang Jiang, Huizi Wang, Xinzi Feng, Xudong Dong
Pages: 926-938
Published online on: 22 May 2020

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Article Open Access

Targeting protein palmitoylation decreases palmitate‑induced sphere formation of human liver cancer cells

Lee‑Won Chong, Chia‑Ling Tsai, Kou‑Ching Yang, Chen‑Chung Liao, Yi‑Chao Hsu
Pages: 939-947
Published online on: 22 May 2020

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Article Open Access

High expression levels and localization of Sox5 in dilated cardiomyopathy

Yafeng Liu, Ben Jiang, Yide Cao, Wen Chen, Li Yin, Yueyue Xu, Zhibing Qiu
Pages: 948-956
Published online on: 22 May 2020

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Article Open Access

Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R

Yuanyuan Cui, Yuting Li, Jiayi Ning, Yajing Mi, Xiaolong  Wang, Zhongying Qiu, Le Li, Xingchun Gou
Pages: 957-963
Published online on: 18 May 2020

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Article Open Access

Protective effect of microRNA‑340‑5p against oxygen‑glucose deprivation/reperfusion in PC12 cells through targeting neuronal differentiation 4

Juan Wang, Ganzhe Liu
Pages: 964-974
Published online on: 22 May 2020

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Article Open Access

Comprehensive investigation of T and B cell receptor repertoires in an MC38 tumor model following murine anti‑PD‑1 administration

Lu Zhang, I‑Ming Wang, Nicolas Solban, Razvan Cristescu, Gefei Zeng, Brian Long
Pages: 975-985
Published online on: 22 May 2020

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Article Open Access

Drug screening and identification of key candidate genes and pathways of rheumatoid arthritis

Yu‑Quan Shi, Wu‑Fang Qi, Chun‑Yu Kong
Pages: 986-996
Published online on: 21 May 2020

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Article Open Access

Long non‑coding RNA‑based risk scoring system predicts prognosis of alcohol‑related hepatocellular carcinoma

Yue Luo, Jiaxiang Ye, Jiazhang Wei, Jinyan Zhang, Yongqiang Li
Pages: 997-1007
Published online on: 22 May 2020

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Article Open Access

MicroRNA‑29a promotes the neural differentiation of rat neural stem/progenitor cells by targeting KLF4

Yunan Gao, Hu Qiao, Tianyu Zhong, Zhen Lu, Yuxia Hou
Pages: 1008-1016
Published online on: 22 May 2020

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Article Open Access

TNF‑α treatment increases DKK1 protein levels in primary osteoblasts via upregulation of DKK1 mRNA levels and downregulation of miR‑335‑5p

Shanshan Li, Yixin Yin, Liping Yao, Ziyi Lin, Shengjun Sun, Jin Zhang, Xiaoyan Li
Pages: 1017-1025
Published online on: 18 May 2020

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Article Open Access

Saikosaponin D inhibits autophagosome‑lysosome fusion and induces autophagy‑independent apoptosis in MDA‑MB‑231 breast cancer cells

Ruoqiu Fu, Lin Zhang, Yuanyuan Li, Bin Li, Yue Ming, Zhiwei Li, Haiyan Xing, Jianhong Chen
Pages: 1026-1034
Published online on: 18 May 2020

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Article Open Access

Klotho downregulation contributes to myocardial damage of cardiorenal syndrome in sepsis

Fei Yan, Yue Feng, Jin Chen, Jing Yan
Pages: 1035-1043
Published online on: 22 May 2020

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Article Open Access

Comparison of neuronal death and expression of TNF‑α and MCT4 in the gerbil hippocampal CA1 region induced by ischemia/reperfusion under hyperthermia to those under normothermia

Taek Geun Ohk, Ji Hyeon Ahn, Young Eun Park, Tae‑Kyeong Lee, Bora Kim, Jae‑Chul Lee, Jun Hwi Cho, Joon Ha Park, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 1044-1052
Published online on: 22 May 2020

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Article

Integrated analysis of miRNA and mRNA expression in the blood of patients with Alzheimer's disease

Zongwen Wang, Lei Shen, Yue Wang, Shuqi Huang
Pages: 1053-1062
Published online on: 20 May 2020

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Article

Antihypertensive drug telmisartan inhibits cell proliferation of gastrointestinal stromal tumor cells in vitro

Hideki Kobara, Shintaro Fujihara, Hisakazu Iwama, Takanori Matsui, Ayako Fujimori, Taiga Chiyo, Shi Tingting, Nobuya Kobayashi, Noriko Nishiyama, Tatsuo Yachida, Tomoko Tadokoro, Kyoko Oura, Joji Tani, Koji Fujita, Takako Nomura, Hirohito Yoneyama, Asahiro Morishita, Keiichi Okano, Yasuyuki Suzuki, Hirohito Mori, Tsutomu Masaki
Pages: 1063-1071
Published online on: 14 May 2020

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Article

LncRNA GAS5 suppresses ER stress‑induced apoptosis and inflammation by regulating SERCA2b in HG‑treated retinal epithelial cell

Lei Jiang, Cun Wang, Xinyue Shen
Pages: 1072-1080
Published online on: 20 May 2020

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Article

Role of DNA damage in the progress of chronic tubule‑interstitial injury

Linxiao Sun, Xiandong Zhu, Jiao Luo, Cheng Wang, Bicheng Chen
Pages: 1081-1089
Published online on: 14 May 2020

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Correction Open Access

[Corrigendum] Protective effects of exendin‑4 on hypoxia/reoxygenation‑induced injury in H9c2 cells

Kai Lu, Guanglei Chang, Lin Ye, Peng Zhang, Yong Li, Dongying Zhang
Pages: 1090-1090
Published online on: 18 May 2020

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Review Open Access

Primary open angle glaucoma genetics: The common variants and their clinical associations (Review)

Alexandra Trivli, Maria I. Zervou, George N. Goulielmos, Demetrios A. Spandidos, Efstathios T. Detorakis
Pages: 1103-1110
Published online on: 09 June 2020

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Article Open Access

Identification of geraldol as an inhibitor of aquaporin‑4 binding by NMO‑IgG

Jie Wang, Shuai Wang, Meiyan Sun, Huijing Xu, Wei Liu, Deli Wang, Lei Zhang, Yan Li, Jiaming Cao, Fang Li, Miao Li
Pages: 1111-1118
Published online on: 04 June 2020

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Article Open Access

Cyclic stretch promotes the ossification of ligamentum flavum by modulating the Indian hedgehog signaling pathway

Rui Gao, Changgui Shi, Chengwei Yang, Yin Zhao, Xiongsheng Chen, Xuhui Zhou
Pages: 1119-1128
Published online on: 02 June 2020

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Article Open Access

Xanthan gum protects temporomandibular chondrocytes from IL‑1β through Pin1/NF‑κB signaling pathway

Fang Yuan, Jian‑Li Xie, Ke‑Yin Liu, Jian‑Liang Shan, Yu‑Gang Sun, Wang‑Gui Ying
Pages: 1129-1136
Published online on: 15 June 2020

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Article Open Access

Echinacoside promotes the proliferation of human renal tubular epithelial cells by blocking the HBX/TREM2‑mediated NF‑κB signalling pathway

Yufan Zhang, Qinfang Wu, Limin Zhong, Lei Wang, Dongwei Gong
Pages: 1137-1144
Published online on: 02 June 2020

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Article Open Access

Transcription box‑3 protects human umbilical vein endothelial cells in a high‑glucose environment through sirtuin 1/AKT signaling

Zhanjiang Yu, Wei Zhang, Xiankun Zhang, Donghui Xu, Na Wang
Pages: 1145-1154
Published online on: 15 June 2020

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Article Open Access

Identification of co‑expression modules and hub genes of retinoblastoma via co‑expression analysis and protein‑protein interaction networks

Yukun Mao, Qingbin Nie, Yang Yang, Gengsheng Mao
Pages: 1155-1168
Published online on: 27 May 2020

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Article Open Access

Superior CKIP-1 sensitivity of orofacial bone-derived mesenchymal stem cells in proliferation and osteogenic differentiation compared to long bone-derived mesenchymal stem cells

Xin Huang, Bingkun Cheng, Wen Song, Le Wang, Yanyuan Zhang, Yan Hou, Yu Song, Liang Kong
Pages: 1169-1178
Published online on: 15 June 2020

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Article Open Access

Septin4 regulates endoplasmic reticulum stress and apoptosis in melatonin‑induced osteoblasts

Lin Tao, Sichao Zhao, Zhengbo Tao, Kaicheng Wen, Siming Zhou, Wacili Da, Yue Zhu
Pages: 1179-1186
Published online on: 15 June 2020

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Article Open Access

TBOPP enhances the anticancer effect of cisplatin by inhibiting DOCK1 in renal cell carcinoma

Wei Zhang, Xiaoxiao Zheng, Shangzhi Xie, Shufen Zhang, Jiayan Mao, Ying Cai, Xuemei Lu, Wei Chen, Haibin Ni, Liping Xie
Pages: 1187-1194
Published online on: 16 June 2020

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Tubeimoside‑1 induces apoptosis in human glioma U251 cells by suppressing PI3K/Akt‑mediated signaling pathways

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Quantitative determination of human serum testosterone via isotope dilution ultra‑performance liquid chromatography tandem mass spectrometry

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Cholestatic models induced by lithocholic acid and α‑naphthylisothiocyanate: Different etiological mechanisms for liver injury but shared JNK/STAT3 signaling

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miR‑192‑5p upregulation mediates the suppression of curcumin in human NSCLC cell proliferation, migration and invasion by targeting c‑Myc and inactivating the Wnt/β‑catenin signaling pathway

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miR‑200c‑3p regulates the proliferation and apoptosis of human trabecular meshwork cells by targeting PTEN

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MicroRNA‑34a inhibits the proliferation and promotes the chemosensitivity of retinoblastoma cells by downregulating Notch1 expression

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MicroRNA‑133b aggravates atherosclerosis by activating the Notch signaling pathway

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Transcription factor AP‑2α negatively regulates thymic stromal lymphopoietin expression in respiratory syncytial virus infection

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Melatonin inhibits the endoplasmic reticulum stress‑induced, C/EBP homologous protein‑mediated pathway in acute pancreatitis

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SB203580 protects against inflammatory response and lung injury in a mouse model of lipopolysaccharide‑induced acute lung injury

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[Corrigendum] Colony‑stimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferation

Fu Hua, Ye Tian, Yingchun Gao, Changhua Li, Xiaoping Liu
Pages: 1663-1663
Published online on: 29 May 2020

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August-2026 Volume 34 Issue 2

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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

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Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

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Article Number: 223
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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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