|
1
|
Miletta NR, Donelan MB and Hivnor CM:
Management of trauma and burn scars: The dermatologist's role in
expanding patient access to care. Cutis. 100:18–20. 2017.PubMed/NCBI
|
|
2
|
van der Veer WM, Bloemen MC, Ulrich MM,
Molema G, van Zuijlen PP, Middelkoop E and Niessen FB: Potential
cellular and molecular causes of hypertrophic scar formation.
Burns. 35:15–29. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Sideek MA, Teia A, Kopecki Z, Cowin AJ and
Gibson MA: Co-localization of LTBP-2 with FGF-2 in fibrotic human
keloid and hypertrophic scar. J Mol Histol. 47:35–45. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zuccaro J, Ziolkowski N and Fish J: A
systematic review of the effectiveness of laser therapy for
hypertrophic burn scars. Clin Plast Surg. 44:767–779. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Willows BM, Ilyas M and Sharma A: Laser in
the management of burn scars. Burns. 43:1379–1389. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Gras C, Ratuszny D, Hadamitzky C, Zhang H,
Blasczyk R and Figueiredo C: miR-145 contributes to hypertrophic
scarring of the skin by inducing myofibroblast activity. Mol Med.
21:296–304. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Wang XQ, Song F and Liu YK: Hypertrophic
scar regression is linked to the occurrence of endothelial
dysfunction. PLoS One. 12:e01766812017. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Liu B, Guo Z and Gao W: miR-181b-5p
promotes proliferation and inhibits apoptosis of hypertrophic scar
fibroblasts through regulating the MEK/ERK/p21 pathway. Exp Ther
Med. 17:1537–1544. 2019.PubMed/NCBI
|
|
9
|
Pyne NJ, Dubois G and Pyne S: Role of
sphingosine 1-phosphate and lysophosphatidic acid in fibrosis.
Biochim Biophys Acta. 1831:228–238. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Schwalm S, Pfeilschifter J and Huwiler A:
Sphingosine-1- phosphate: A Janus-faced mediator of fibrotic
diseases. Biochim Biophys Acta. 1831:239–250. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ravichandran S, Finlin BS, Kern PA and
Özcan S: Sphk2(−/-) mice are protected from obesity and insulin
resistance. Biochim Biophys Acta Mol Basis Dis. 1865:570–576. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Schwalm S, Timcheva TM, Filipenko I, Ebadi
M, Hofmann LP, Zangemeister-Wittke U, Pfeilschifter J and Huwiler
A: Sphingosine kinase 2 deficiency increases proliferation and
migration of renal mouse mesangial cells and fibroblasts. Biol
Chem. 396:813–825. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Schwalm S, Beyer S, Frey H, Haceni R,
Grammatikos G, Thomas D, Geisslinger G, Schaefer L, Huwiler A and
Pfeilschifter J: Sphingosine kinase-2 deficiency ameliorates kidney
fibrosis by up-regulating Smad7 in a mouse model of unilateral
ureteral obstruction. Am J Pathol. 187:2413–2429. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhou J, Chen J and Yu H: Targeting
sphingosine kinase 2 by ABC294640 inhibits human skin squamous cell
carcinoma cell growth. Biochem Biophys Res Commun. 497:535–542.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Shin SH, Cho KA, Hahn S, Lee Y, Kim YH,
Woo SY, Ryu KH, Park WJ and Park JW: Inhibiting sphingosine kinase
2 derived-sphingosine-1-phosphate ameliorates psoriasis-like skin
disease via blocking Th17 differentiation of naive CD4 T
lymphocytes in mice. Acta Derm Venereol. 99:594–601. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Shi J, Li J, Guan H, Cai W, Bai X, Fang X,
Hu X, Wang Y, Wang H, Zheng Z, et al: Anti-fibrotic actions of
interleukin-10 against hypertrophic scarring by activation of
PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts.
PLoS One. 9:e982282014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zuo J, Chen Z, Zhong X, Lan W, Kuang Y and
Huang D: FBP1 is highly expressed in human hypertrophic scars and
increases fibroblast proliferation, apoptosis, and collagen
expression. Connect Tissue Res. 59:120–128. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Chen H, Xu Y, Yang G, Zhang Q, Huang X, Yu
L and Dong X: Mast cell chymase promotes hypertrophic scar
fibroblast proliferation and collagen synthesis by activating
TGF-β1/Smads signaling pathway. Exp Ther Med. 14:4438–4442.
2017.PubMed/NCBI
|
|
19
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Xiao Y, Xu D, Song H, Shu F, Wei P, Yang
X, Zhong C, Wang X, Müller WE, Zheng Y, et al: Cuprous oxide
nanoparticles reduces hypertrophic scarring by inducing fibroblast
apoptosis. Int J Nanomedicine. 14:5989–6000. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhou Y, Zhao Y, Du H, Suo Y, Chen H, Li H,
Liang X, Li Q and Huang X: Downregulation of CFTR is involved in
the formation of hypertrophic scars. Biomed Res Int.
2020:95262892020.PubMed/NCBI
|
|
22
|
Song Y, Guo B, Ma S, Chang P and Tao K:
Naringin suppresses the growth and motility of hypertrophic scar
fibroblasts by inhibiting the kinase activity of Akt. Biomed
Pharmacother. 105:1291–1298. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhou X, Xie Y, Xiao H, Deng X, Wang Y,
Jiang L, Liu C and Zhou R: MicroRNA-519d inhibits proliferation and
induces apoptosis of human hypertrophic scar fibroblasts through
targeting Sirtuin 7. Biomed Pharmacother. 100:184–190. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Qiu W, Yang Z, Fan Y and Zheng Q:
MicroRNA-613 inhibits cell growth, migration and invasion of
papillary thyroid carcinoma by regulating SphK2. Oncotarget.
7:39907–39915. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhang L, Liu X, Zuo Z, Hao C and Ma Y:
Sphingosine kinase 2 promotes colorectal cancer cell proliferation
and invasion by enhancing MYC expression. Tumor Biol. 37:8455–8460.
2016. View Article : Google Scholar
|
|
26
|
Leili H, Nasser S, Nadereh R, Siavoush D
and Pouran K: Sphingosine kinase-2 inhibitor ABC294640 enhances
doxorubicin-induced apoptosis of NSCLC cells via altering survivin
expression. Drug Res (Stuttg). 68:45–53. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Xiao Y, Liu R, Li X, Gurley EC, Hylemon
PB, Lu Y, Zhou H and Cai W: Long noncoding RNA H19 contributes to
cholangiocyte proliferation and cholestatic liver fibrosis in
biliary atresia. Hepatology. 70:1658–1673. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang XC, Wang T, Zhang Y, Wang LL, Zhao RY
and Tan W: Tacrolimus inhibits proliferation and induces apoptosis
by decreasing survivin in scar fibroblasts after glaucoma surgery.
Eur Rev Med Pharmacol Sci. 22:2934–2940. 2018.PubMed/NCBI
|
|
29
|
Li XY, Li T, Li XJ, Wang JN and Chen Z:
TSG-6 induces apoptosis of human hypertrophic scar fibroblasts via
activation of the Fas/FasL signalling pathway. Folia Biol (Praha).
64:173–181. 2018.PubMed/NCBI
|
|
30
|
Zhang G, Zheng H, Zhang G, Cheng R, Lu C,
Guo Y and Zhao G: MicroRNA-338-3p suppresses cell proliferation and
induces apoptosis of non-small-cell lung cancer by targeting
sphingosine kinase 2. Cancer Cell Int. 17:462017. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fan X, Yuan J, Xie J, Pan Z, Yao X, Sun X,
Zhang P and Zhang L: Long non-protein coding RNA DANCR functions as
a competing endogenous RNA to regulate osteoarthritis progression
via miR-577/SphK2 axis. Biochem Biophys Res Commun. 500:658–664.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ma L, Li LY and Zhao TL: Anti-inflammatory
effects of ginsenoside Rg3 on the hypertrophic scar formation via
the NF-κB/IκB signaling pathway in rabbit ears. Pharmazie.
75:102–106. 2020.PubMed/NCBI
|
|
33
|
Volk SW, Wang Y, Mauldin EA, Liechty KW
and Adams SL: Diminished type III collagen promotes myofibroblast
differentiation and increases scar deposition in cutaneous wound
healing. Cells Tissues Organs. 194:25–37. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zhou R, Zhang Q, Zhang Y, Fu S and Wang C:
Aberrant miR-21 and miR-200b expression and its pro-fibrotic
potential in hypertrophic scars. Exp Cell Res. 339:360–366. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Nicholas SE, Rowsey TG, Priyadarsini S,
Mandal NA and Karamichos D: Unravelling the interplay of
sphingolipids and TGF-β signaling in the human corneal stroma. PLoS
One. 12:e01823902017. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Zhang Y, Shan S, Wang J, Cheng X, Yi B,
Zhou J and Li Q: Galangin inhibits hypertrophic scar formation via
ALK5/Smad2/3 signaling pathway. Mol Cell Biochem. 413:109–118.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zhao JC, Zhang BR, Shi K, Wang J, Yu QH
and Yu JA: Lower energy radial shock wave therapy improves
characteristics of hypertrophic scar in a rabbit ear model. Exp
Ther Med. 15:933–939. 2018.PubMed/NCBI
|
|
38
|
Chen H, Xu Y, Yang G, Zhang Q, Huang X, Yu
L and Dong X: Mast cell chymase promotes hypertrophic scar
fibroblast proliferation and collagen synthesis by activating
TGF-β1/Smads signaling pathway. Exp Ther Med. 14:4438–4442.
2017.PubMed/NCBI
|
|
39
|
Seki N, Toh U, Kawaguchi K, Ninomiya M,
Koketsu M, Watanabe K, Aoki M, Fujii T, Nakamura A, Akagi Y, et al:
Tricin inhibits proliferation of human hepatic stellate cells in
vitro by blocking tyrosine phosphorylation of PDGF receptor and its
signaling pathways. J Cell Biochem. 113:2346–2355. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Wu SP, Yang Z, Li FR, Liu XD, Chen HT and
Su DN: Smad7-overexpressing rat BMSCs inhibit the fibrosis of
hepatic stellate cells by regulating the TGF-β1/Smad signaling
pathway. Exp Ther Med. 14:2568–2576. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Tang B, Zhu B, Liang Y, Bi L, Hu Z, Chen
B, Zhang K and Zhu J: Asiaticoside suppresses collagen expression
and TGF-β/Smad signaling through inducing Smad7 and inhibiting
TGF-βRI and TGF-βRII in keloid fibroblasts. Arch Dermatol Res.
303:563–572. 2011. View Article : Google Scholar : PubMed/NCBI
|
