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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2020 Volume 22 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Telomerase and telomeres in aging theory and chronographic aging theory (Review)

Mayya P. Razgonova, Alexander M. Zakharenko, Kirill S. Golokhvast, Maria Thanasoula, Evangelia Sarandi, Konstantinos Nikolouzakis, Persefoni Fragkiadaki, Dimitris Tsoukalas, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 1679-1694
Published online on: 25 June 2020

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Review

A potential role for astaxanthin in the treatment of bone diseases (Review)

Maria Teresa Valenti, Massimiliano Perduca, Maria Grazia Romanelli, Monica Mottes, Luca Dalle Carbonare
Pages: 1695-1701
Published online on: 26 June 2020

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Article Open Access

Expression of Notch family is altered in non‑alcoholic fatty liver disease

Wen‑Jin Ding, Wei‑Jie Wu, Yuan‑Wen Chen, Han‑Bei Chen, Jian‑Gao Fan, Liang Qiao
Pages: 1702-1708
Published online on: 17 June 2020

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Article Open Access

Genome‑wide analysis of DNA methylation and gene expression changes in an ovalbumin‑induced asthma mouse model

Joong‑Sun Kim, In‑Sik Shin, Na‑Rae Shin, Jae‑Yong Nam, Chul Kim
Pages: 1709-1716
Published online on: 17 June 2020

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Article Open Access

miR‑27a‑3p negatively regulates osteogenic differentiation of MC3T3‑E1 preosteoblasts by targeting osterix

Yuexin Xu, Dong Li, Zhu Zhu, Lingyun Li, Yucui Jin, Changyan Ma, Wei Zhang
Pages: 1717-1726
Published online on: 17 June 2020

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Article Open Access

Effects of GPR81 silencing combined with cisplatin stimulation on biological function in hypopharyngeal squamous cell carcinoma

Qiaojing Jia, Ou Xu, Jianxing Wang, Jinhui Dong, Xiumin Ren, Xiaofang Jia, Chunguang Shan
Pages: 1727-1736
Published online on: 18 June 2020

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Article Open Access

Mmu_circ_003795 regulates osteoblast differentiation and mineralization in MC3T3‑E1 and MDPC23 by targeting COL15A1

Jingwen Wu, Wen Ren, Zhichao Zheng, Zhu Huang, Tingting Liang, Fuyao Li, Zhan Shi, Qianzhou Jiang, Xuechao Yang, Lvhua Guo
Pages: 1737-1746
Published online on: 22 June 2020

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Article Open Access

Liriopesides B from Liriope spicata var. prolifera inhibits metastasis and induces apoptosis in A2780 human ovarian cancer cells

Haizhong Yu, Haiyan Wang, Youping Yin, Zhongkang Wang
Pages: 1747-1758
Published online on: 18 June 2020

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Article Open Access

Exogenous hydrogen sulfide reduces atrial remodeling and atrial fibrillation induced by diabetes mellitus via activation of the PI3K/Akt/eNOS pathway

Xiaofei Xue, Xinyu Ling, Wang Xi, Pei Wang, Jianjun Sun, Qian Yang, Jian Xiao
Pages: 1759-1766
Published online on: 30 June 2020

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Article Open Access

Silencing of BRF2 inhibits the growth and metastasis of lung cancer cells

Yuan Bian, Qiu Li, Qiaolian Li, Ruigen Pan
Pages: 1767-1774
Published online on: 26 June 2020

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Article Open Access

Risk gene identification and support vector machine learning to construct an early diagnosis model of myocardial infarction

Hong‑Zhi Fang, Dan‑Li Hu, Qin Li, Su Tu
Pages: 1775-1782
Published online on: 17 June 2020

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Article Open Access

Calcium inhibitor inhibits high glucose‑induced hypertrophy of H9C2 cells

Xiaohong Xu, Luoyang Ruan, Xiaohua Tian, Fengjuan Pan, Cailan Yang, Guosheng Liu
Pages: 1783-1792
Published online on: 26 June 2020

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Article Open Access

Toosendanin induces apoptosis of MKN‑45 human gastric cancer cells partly through miR‑23a‑3p‑mediated downregulation of BCL2

Shuli Shao, Shanshan Li, Chang Liu, Weiwei Zhang, Zhenzhu Zhang, Shaowei Zhu, Yunjianan Feng, Yang Pan
Pages: 1793-1802
Published online on: 22 June 2020

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Article Open Access

MicroRNA‑375 prevents TGF‑β‑dependent transdifferentiation of lung fibroblasts via the MAP2K6/P38 pathway

Xinghua Zhang, Qian Chen, Hengya Song, Wanli Jiang, Songping Xie, Jie Huang, Ganjun Kang
Pages: 1803-1810
Published online on: 22 June 2020

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Article Open Access

Long non‑coding RNA HOTAIR promotes burn wound healing by regulating epidermal stem cells

Yan Shi, Ronghua Yang, Longxiang Tu, Dewu Liu
Pages: 1811-1820
Published online on: 23 June 2020

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Article Open Access

Effects of the NF‑κB/p53 signaling pathway on intervertebral disc nucleus pulposus degeneration

Litao Zhang, Xiujuan Li, Xue Kong, Hua Jin, Yaoqi Han, Yuanzhong Xie
Pages: 1821-1830
Published online on: 30 June 2020

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Article Open Access

Peroxiredoxin I deficiency increases pancreatic β‑cell apoptosis after streptozotocin stimulation via the AKT/GSK3β signaling pathway

Mei‑Hua Jin, Gui‑Nan Shen, Ying‑Hua Jin, Hu‑Nan Sun, Xing Zhen, Yong‑Qing Zhang, Dong‑Seok Lee, Yu‑Dong Cui, Li‑Yun Yu, Ji‑Su Kim, Taeho Kwon, Ying‑Hao Han
Pages: 1831-1838
Published online on: 26 June 2020

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Article Open Access

Tanshinone IIA promotes cardiac differentiation and improves cell motility by modulating the Wnt/β‑catenin signaling pathway

Kun Li, Xiuyan Wang, Chenxing Fan, Chunxia Wu, Shizheng Li, Hua Liu
Pages: 1839-1846
Published online on: 24 June 2020

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Article Open Access

Role of DRAM1 in mitophagy contributes to preeclampsia regulation in mice

Guoqing Chen, Ying Lin, Lu Chen, Fa Zeng, Li Zhang, Yan Huang, Pingping Huang, Lingling Liao, Yuanlan Yu
Pages: 1847-1858
Published online on: 23 June 2020

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Article Open Access

Age‑related changes in mineralocorticoid receptors in rat hearts

Danli Hu, Ruolan Dong, Yanjun Zhang, Yan Yang, Zhihui Chen, Ying Tang, Menglu Fu, Xizhen Xu, Ling Tu
Pages: 1859-1867
Published online on: 19 June 2020

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Article Open Access

Identification of potential markers for type 2 diabetes mellitus via bioinformatics analysis

Yana Lu, Yihang Li, Guang Li, Haitao Lu
Pages: 1868-1882
Published online on: 26 June 2020

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Article Open Access

miR‑802 inhibits the epithelial‑mesenchymal transition, migration and invasion of cervical cancer by regulating BTF3

Xiuhui Wu, Leng Liu, Hongxia Zhang
Pages: 1883-1891
Published online on: 23 June 2020

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Article Open Access

Aggravated intestinal ischemia‑reperfusion injury is associated with activated mitochondrial autophagy in a mouse model of diabetes

Zi Zeng, Hui‑Min Liu, Yun‑Yan Zhang, Rong Chen, Tao Sun, Wei Li, Qian Sun, Zhong‑Yuan Xia, Qing‑Tao Meng
Pages: 1892-1900
Published online on: 24 June 2020

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Article Open Access

2‑Hydroxypropyl‑β‑cyclodextrin blocks autophagy flux and triggers caspase‑8‑mediated apoptotic cascades in HepG2 cells

Haidong Sun, Huajie Zong, Gang Wu
Pages: 1901-1909
Published online on: 26 June 2020

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Article Open Access

Human apolipoprotein L1 interferes with mitochondrial function in Saccharomyces cerevisiae

Mounia Chidiac, Jalil Daher, Mélanie Boeckstaens, Philippe Poelvoorde, Bassam Badran, Anna Maria Marini, Roy Khalaf, Luc Vanhamme
Pages: 1910-1920
Published online on: 24 June 2020

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Article Open Access

Downregulation of microRNA‑29c reduces pain after child delivery by activating the oxytocin‑GABA pathway

Caijuan Li, Xian Wang, Guangfen Zhang, Yao Zhang, Fan Xia, Shiqin Xu, Xiaofeng Shen
Pages: 1921-1931
Published online on: 26 June 2020

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Article Open Access

Circulating extracellular vesicles from patients with breast cancer enhance migration and invasion via a Src‑dependent pathway in MDA‑MB‑231 breast cancer cells

Javier Ramírez‑Ricardo, Elizabeth Leal‑Orta, Elia Martínez‑Baeza, Carlos Ortiz‑Mendoza, Fernando Breton‑Mora, Analy Herrera‑Torres, Irma Elizalde‑Acosta, Pedro Cortes‑Reynosa, Rocio Thompson‑Bonilla, Eduardo Perez Salazar
Pages: 1932-1948
Published online on: 18 June 2020

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Article Open Access

Wild‑type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells

Xiaopeng Shen, Shen Wu, Jingyi Zhang, Meng Li, Feng Xu, Ao Wang, Yang Lei, Guoping Zhu
Pages: 1949-1957
Published online on: 18 June 2020

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Article Open Access

Expression profiling of circular RNAs and their potential role in early‑stage diabetic cardiomyopathy

Shengzhong Dong, Chunyan Tu, Xing Ye, Liliang Li, Mingchang Zhang, Aimin Xue, Shangheng Chen, Ziqin Zhao, Bin Cong, Junyi Lin, Yiwen Shen
Pages: 1958-1968
Published online on: 17 June 2020

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Article Open Access

Butorphanol protects PC12 cells against OGD/R-induced inflammation and apoptosis

Zijing Yang, Li Wang, Yingjun Hu, Feixiang Wang
Pages: 1969-1975
Published online on: 30 June 2020

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Article Open Access

oxLDL promotes podocyte migration by regulating CXCL16, ADAM10 and ACTN4

Yuan Chen, Zhiyi Wang, Qian Li, Lichun Yu, Yanji Zhu, Jing Wang, Shuzhen Sun
Pages: 1976-1984
Published online on: 30 June 2020

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Article Open Access

Anti‑inflammatory activity of 3,5,6,7,3',4'‑hexamethoxyflavone via repression of the NF‑κB and MAPK signaling pathways in LPS‑stimulated RAW264.7 cells

Eun Suk Son, Jeong‑Woong Park, Se‑Hee Kim, Hye Ran Park, Woorijarang Han, O Chul Kwon, Jae Young Nam, Sung Hwan Jeong, Chang Soo Lee
Pages: 1985-1993
Published online on: 18 June 2020

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Article Open Access

Scorpion primer PCR analysis for genotyping of allele variants of thiopurine s‑methyltransferase*3

Pu Yao, Xue‑Mei Qu, Sai Ren, Xiao‑Dong Ren, Ning Su, Na Zhao, Liu Wang, Lin Cheng, Bang‑Bi Weng, Feng‑Jun Sun, Qing Huang
Pages: 1994-2002
Published online on: 26 June 2020

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Article Open Access

Appropriate timing for hypothermic machine perfusion to preserve livers donated after circulatory death

Xiaoyan Hu, Wei Wang, Cheng Zeng, Weiyang He, Zibiao Zhong, Zhongzhong Liu, Yanfeng Wang, Qifa Ye
Pages: 2003-2011
Published online on: 18 June 2020

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Article Open Access

Antibodies specific to ferritin light chain polypeptide are frequently detected in patients with immune‑related pancytopenia

Shanfeng Hao, Yang Zhang, Luogang Hua, Ning Xie, Na Xiao, Huaquan Wang, Rong Fu, Zonghong Shao
Pages: 2012-2020
Published online on: 26 June 2020

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Article Open Access

Activation of calcium‑sensing receptor‑mediated autophagy in high glucose‑induced cardiac fibrosis in vitro

Hui Yuan, Jiyu Xu, Yanfei Zhu, Li Li, Qi Wang, Yaquan Yu, Bin Zhou, Yi Liu, Xiaoyi Xu, Zhilong Wang
Pages: 2021-2031
Published online on: 26 June 2020

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Article Open Access

Anti‑chondrocyte apoptosis effect of genistein in treating inflammation‑induced osteoarthritis

Yang Zou, Qiming Liu, Piaoting Guo, Yang Huang, Zhengcong Ye, Jiong Hu
Pages: 2032-2042
Published online on: 18 June 2020

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Article Open Access

Stress response in periodontal ligament stem cells may contribute to bisphosphonate‑associated osteonecrosis of the jaw: A gene expression array analysis

Yueqi Shi, Mengyu Li, Yejia Yu, Yuqiong Zhou, Wenjie Zhang, Hongfei Hua, Shaoyi Wang
Pages: 2043-2051
Published online on: 26 June 2020

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Article Open Access

Statin rosuvastatin inhibits apoptosis of human coronary artery endothelial cells through upregulation of the JAK2/STAT3 signaling pathway

Kuijing Wang, Bo Li, Yuanyuan Xie, Nan Xia, Minghui Li, Guang Gao
Pages: 2052-2062
Published online on: 23 June 2020

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Article Open Access

Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells

Jia-Mou Ren, Shu-Li Zhang, Xiao-Ling Wang, Zhi-Zhong Guan, Xiao-Lan Qi
Pages: 2063-2075
Published online on: 18 June 2020

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Article Open Access

Protective and inhibitory effects of acteoside from Abeliophyllum distichum Nakai against oxidative DNA damage

Tae Won Jang, Ji Soo Choi, Jae Ho Park
Pages: 2076-2084
Published online on: 18 June 2020

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Article

miR‑142‑5p inhibits pancreatic cancer cell migration and invasion by targeting PIK3CA

Jing Zhu, Leilei Zhou, Bin Wei, Zhaoye Qian, Jiru Wang, Hongxia Hui, Yuan Sun
Pages: 2085-2092
Published online on: 18 June 2020

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Article

A twin‑pair analysis indicates congenital scoliosis is associated with allele‑specific methylation in the SVIL gene

Zhifa Zhang, Yongjun Chen, Yuezhou Wu, Yongyu Hao, Xuelin Zhao, Xiangyu Wang, Yan Wang, Yanhai Xi, Xuesong Zhang
Pages: 2093-2100
Published online on: 24 June 2020

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Article

Aquaporin‑4 deletion ameliorates enterovirus 71 infection in mice

Lei Zhu, Xiuwei Hao, Xiaole Wu, Boxiang Qi, Ting Yue, Haijun Wang
Pages: 2101-2106
Published online on: 23 June 2020

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Article

Vitamin D protects against necrotising enterocolitis in newborn mice by activating the ERK signalling pathway

Chunmei Lyu, Suhua Jiang, Muxian Kong, Xiaoqian Chen, Li Zhang
Pages: 2107-2114
Published online on: 26 June 2020

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Article

A critical role for miR‑135a‑5p‑mediated regulation of SLC24A2 in neuropathic pain

Xiao‑Gang Zhou, Hui He, Pei‑Ji Wang
Pages: 2115-2122
Published online on: 22 June 2020

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Article

Downregulation of miR‑486‑5p alleviates LPS‑induced inflammatory injury, oxidative stress and apoptosis in Chondrogenic cell ATDC5 by targeting NRF1

Qing Chang, Mingliang Ji, Chao Li, Rui Geng
Pages: 2123-2131
Published online on: 30 June 2020

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Article

Effectiveness of Bailing capsules in the treatment of lupus nephritis: A meta‑analysis

Yue Li, Tianhua Xu, Xiaobo Qiu, Binyao Tian, Chao Bi, Li Yao
Pages: 2132-2140
Published online on: 30 June 2020

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Correction Open Access

[Corrigendum] Pro‑neurogenic effects of andrographolide on RSC96 Schwann cells in vitro

Fuben Xu, Huayu Wu, Kun Zhang, Peizhen Lv, Li Zheng, Jinmin Zhao
Pages: 2141-2141
Published online on: 26 June 2020

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Review Open Access

Cellular senescence: A pathogenic mechanism of pelvic organ prolapse (Review)

Liwei Huang, Zhiwei Zhao, Jirui Wen, Wang Ling, Yali Miao, Jiang Wu
Pages: 2155-2162
Published online on: 13 July 2020

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Review Open Access

Significance of taurine transporter (TauT) in homeostasis and its layers of regulation (Review)

Stella Baliou, Anthony M. Kyriakopoulos, Maria Goulielmaki, Michalis I. Panayiotidis, Demetrios A. Spandidos, Vassilios Zoumpourlis
Pages: 2163-2173
Published online on: 09 July 2020

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Article Open Access

Trimetazidine improves hepatic lipogenesis and steatosis in non‑alcoholic fatty liver disease via AMPK‑ChREBP pathway

Ying Zhang, Can Li, Xiuqi Li, Cheng Wu, Haiyan Zhou, Shuang Lu, Xingde Liu
Pages: 2174-2182
Published online on: 08 July 2020

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Article Open Access

Sphingosine kinase 1 contributes to doxorubicin resistance and glycolysis in osteosarcoma

Xiaojun Ren, Chunhong Su
Pages: 2183-2190
Published online on: 03 July 2020

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Article Open Access

Levistilide A reverses rat hepatic fibrosis by suppressing angiotensin II‑induced hepatic stellate cells activation

Shu Li, Wei Zhao, Zhimin Zhao, Binbin Cheng, Shuang Li, Chenghai Liu
Pages: 2191-2198
Published online on: 10 July 2020

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Article Open Access

Downregulation of miR‑193a‑3p via targeting cyclin D1 in thyroid cancer

Xiao‑Jiao Li, Rong Wen, Dong‑Yue Wen, Peng Lin, Deng‑Hua Pan, Li‑Jie Zhang, Yu He, Lin Shi, Yong‑Ying Qin, Yun‑Hui Lai, Jing‑Ni Lai, Jun‑Lin Yang, Qin‑Qiao Lai, Jun Wang, Jun Ma, Hong Yang, Yu‑Yan Pang
Pages: 2199-2218
Published online on: 08 July 2020

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Article Open Access

Suppression of sirtuin 1 alleviates airway inflammation through mTOR‑mediated autophagy

Yuanyuan Wu, Wei Li, Yifan Hu, Yun Liu, Xiuzhen Sun
Pages: 2219-2226
Published online on: 13 July 2020

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Article Open Access

lncRNA‑MM2P downregulates the production of pro‑inflammatory cytokines in acute gouty arthritis

Xifeng Zhang, Ying Zou, Jiangxia Zheng, Senguo Ji, Xiuzhen Wen, Feng Ye, Ju Liu, Xueyong Li, Jin Lei, Mingliang Qiu
Pages: 2227-2234
Published online on: 09 July 2020

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Article Open Access

Combined administration of SHP2 inhibitor SHP099 and the α7nAChR agonist PNU282987 protect mice against DSS‑induced colitis

Junhua Xiao, Gufang Zhang, Sujun Gao, Jiaqing Shen, Huang Feng, Zhilong He, Chunfang Xu
Pages: 2235-2244
Published online on: 10 July 2020

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Article Open Access

CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Pages: 2245-2252
Published online on: 13 July 2020

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Article Open Access

Role of ROCK/NF‑κB/AQP8 signaling in ethanol‑induced intestinal epithelial barrier dysfunction

Hang Zhao, Xiaonan Sun, Jing Tong
Pages: 2253-2262
Published online on: 09 July 2020

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Article Open Access

Shikonin inhibits CEBPD downregulation in IL‑17‑treated HaCaT cells and in an imiquimod‑induced psoriasis model

Xiao‑Ou Lan, He‑Xiao Wang, Rui‑Qun Qi, Yuan‑Yuan Xu, Ya‑Jie  Yu, Yang Yang, Hao Guo, Xing‑Hua Gao, Long Geng
Pages: 2263-2272
Published online on: 09 July 2020

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Identification of a novel homozygous variant in the CNGA1 gene in a Chinese family with autosomal recessive retinitis pigmentosa

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Influence of reaming intramedullary nailing on MSC population after surgical treatment of patients with long bone fracture

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Weighted gene co‑expression network analysis identifies key genes from extracellular vesicles as potential prognostic biomarkers for congenital pulmonary stenosis

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MicroRNA‑204‑5p inhibits the osteogenic differentiation of ankylosing spondylitis fibroblasts by regulating the Notch2 signaling pathway

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Cucurbitacin I induces apoptosis in ovarian cancer cells through oxidative stress and the p190B‑Rac1 signaling axis

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Puerarin restores the autophagic flux to alleviate cadmium‑induced endoplasmic reticulum stress in NRK‑52E cells

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Montelukast improves bronchopulmonary dysplasia by inhibiting epithelial‑mesenchymal transition via inactivating the TGF‑β1/Smads signaling pathway

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Inhibition of sphingosine kinase 2 attenuates hypertrophic scar formation via upregulation of Smad7 in human hypertrophic scar fibroblasts

Jian Zeng, Bin Jiang, Xia Xiao, Rou Zhang
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Clinical characteristics of 2019 novel coronavirus pneumonia in Zhejiang province, China

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Pages: 2583-2587
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

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Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Ayman A. Althubity
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
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Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Article Number: 25
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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

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Article Number: 21
Published online on: 29 October 2025

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Article Number: 20
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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
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Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
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Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

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Article Number: 10
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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
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February-2026 Volume 33 Issue 2

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CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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Mitophagy and oxidative stress in chronic kidney disease (Review)

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Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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