|
1
|
Black CK, Termanini KM, Aguirre O,
Hawksworth JS and Sosin M: Solid organ transplantation in the 21st
century. Ann Transl Med. 6:4092018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Czigany Z, Lurje I, Schmelzle M, Schöning
W, Öllinger R, Raschzok N, Sauer IM, Tacke F, Strnad P, Trautwein
C, et al: Ischemia-reperfusion injury in marginal liver grafts and
the role of hypothermic machine perfusion: Molecular mechanisms and
clinical implications. J Clin Med. 9:8462020. View Article : Google Scholar
|
|
3
|
Kadono K, Gruszynski M, Azari K and
Kupiec-Weglinski JW: Vascularized composite allotransplantation
versus solid organ transplantation: Innate-adaptive immune
interphase. Curr Opin Organ Transplant. 24:714–720. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Nastos C, Kalimeris K, Papoutsidakis N,
Tasoulis MK, Lykoudis PM, Theodoraki K, Nastou D, Smyrniotis V and
Arkadopoulos N: Global consequences of liver ischemia/reperfusion
injury. Oxid Med Cell Longev. 2014:9069652014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sun P, Zhang P, Wang PX, Zhu LH, Du Y,
Tian S, Zhu X and Li H: Mindin deficiency protects the liver
against ischemia/reperfusion injury. J Hepatol. 63:1198–1211. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
van Riel WG, van Golen RF, Reiniers MJ,
Heger M and van Gulik TM: How much ischemia can the liver tolerate
during resection? Hepatobiliary Surg Nutr. 5:58–71. 2016.PubMed/NCBI
|
|
7
|
Peralta C, Jiménez-Castro MB and
Gracia-Sancho J: Hepatic ischemia and reperfusion injury: Effects
on the liver sinusoidal milieu. J Hepatol. 59:1094–1106. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Lu L, Zhou H, Ni M, Wang X, Busuttil R,
Kupiec-Weglinski J and Zhai Y: Innate immune regulations and liver
ischemia-reperfusion injury. Transplantation. 100:2601–2610. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Guan LY, Fu PY, Li PD, Li ZN, Liu HY, Xin
MG and Li W: Mechanisms of hepatic ischemia-reperfusion injury and
protective effects of nitric oxide. World J Gastrointest Surg.
6:122–128. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhai Y, Petrowsky H, Hong JC, Busuttil RW
and Kupiec-Weglinski JW: Ischaemia-reperfusion injury in liver
transplantation--from bench to bedside. Nat Rev Gastroenterol
Hepatol. 10:79–89. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li S, Yi Z, Deng M, Scott MJ, Yang C, Li
W, Lei Z, Santerre NM, Loughran P and Billiar TR: TSLP protects
against liver I/R injury via activation of the PI3K/Akt pathway.
JCI Insight. 4:1290132019. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Covington SM, Bauler LD and Toledo-Pereyra
LH: Akt: A therapeutic target in hepatic ischemia-reperfusion
injury. J Invest Surg. 30:47–55. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Parhiz H, Roohbakhsh A, Soltani F, Rezaee
R and Iranshahi M: Antioxidant and anti-inflammatory properties of
the citrus flavonoids hesperidin and hesperetin: An updated review
of their molecular mechanisms and experimental models. Phytother
Res. 29:323–331. 2015. View
Article : Google Scholar : PubMed/NCBI
|
|
14
|
Elhelaly AE, AlBasher G, Alfarraj S,
Almeer R, Bahbah EI, Fouda MMA, Bungău SG, Aleya L and Abdel-Daim
MM: Protective effects of hesperidin and diosmin against
acrylamide-induced liver, kidney, and brain oxidative damage in
rats. Environ Sci Pollut Res Int. 26:35151–35162. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Pandey P, Sayyed U, Tiwari RK, Siddiqui
MH, Pathak N and Bajpai P: Hesperidin induces ROS-mediated
apoptosis along with cell cycle arrest at G2/M phase in human gall
bladder carcinoma. Nutr Cancer. 71:676–687. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mo'men YS, Hussein RM and Kandeil MA:
Involvement of PI3K/Akt pathway in the protective effect of
hesperidin against a chemically induced liver cancer in rats. J
Biochem Mol Toxicol. 33:e223052019.PubMed/NCBI
|
|
17
|
Qin Z, Chen L, Liu M, Tan H and Zheng L:
Hesperidin reduces adverse symptomatic intracerebral hemorrhage by
promoting TGF-β1 for treating ischemic stroke using tissue
plasminogen activator. Neurol Sci. 41:139–147. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Qi W, Lin C, Fan K, Chen Z, Liu L, Feng X,
Zhang H, Shao Y, Fang H, Zhao C, et al: Hesperidin inhibits
synovial cell inflammation and macrophage polarization through
suppression of the PI3K/AKT pathway in complete Freund's
adjuvant-induced arthritis in mice. Chem Biol Interact. 306:19–28.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Selim NM, Elgazar AA, Abdel-Hamid NM,
El-Magd MRA, Yasri A, Hefnawy HME and Sobeh M: Chrysophanol,
physcion, hesperidin and curcumin modulate the gene expression of
pro-inflammatory mediators induced by LPS in HepG2: In silico and
molecular studies. Antioxidants. 8:3712019. View Article : Google Scholar
|
|
20
|
Jo SH, Kim ME, Cho JH, Lee Y, Lee J, Park
YD and Lee JS: Hesperetin inhibits neuroinflammation on microglia
by suppressing inflammatory cytokines and MAPK pathways. Arch Pharm
Res. 42:695–703. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Justin-Thenmozhi A, Dhivya Bharathi M,
Kiruthika R, Manivasagam T, Borah A and Essa MM: Attenuation of
aluminum chloride-induced neuroinflammation and caspase activation
through the AKT/GSK-3β pathway by hesperidin in wistar rats.
Neurotox Res. 34:463–476. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Li X, Hu X, Wang J, Xu W, Yi C, Ma R and
Jiang H: Short-term hesperidin pretreatment attenuates rat
myocardial ischemia/reperfusion injury by inhibiting high mobility
group box 1 protein expression via the PI3K/Akt pathway. Cell
Physiol Biochem. 39:1850–1862. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Park HK, Kang SW and Park MS: Hesperidin
ameliorates hepatic ischemia-reperfusion injury in Sprague-Dawley
rats. Transplant Proc. 51:2828–2832. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Yazdani HO, Chen HW, Tohme S, Tai S, van
der Windt DJ, Loughran P, Rosborough BR, Sud V, Beer-Stolz D,
Turnquist HR, et al: IL-33 exacerbates liver sterile inflammation
by amplifying neutrophil extracellular trap formation. J Hepatol.
68:130–139. 2017. View Article : Google Scholar
|
|
25
|
Lei Z, Deng M, Yi Z, Sun Q, Shapiro RA, Xu
H, Li T, Loughran PA, Griepentrog JE, Huang H, et al: cGAS-mediated
autophagy protects the liver from ischemia-reperfusion injury
independently of STING. Am J Physiol Gastrointest Liver Physiol.
314:G655–G667. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sun Q, Loughran P, Shapiro R, Shrivastava
IH, Antoine DJ, Li T, Yan Z, Fan J, Billiar TR and Scott MJ:
Redox-dependent regulation of hepatocyte absent in melanoma 2
inflammasome activation in sterile liver injury in mice.
Hepatology. 65:253–268. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Konishi T and Lentsch AB: Hepatic
ischemia/reperfusion: Mechanisms of tissue injury, repair, and
regeneration. Gene Expr. 17:277–287. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Abu-Amara M, Yang SY, Tapuria N, Fuller B,
Davidson B and Seifalian A: Liver ischemia/reperfusion injury:
Processes in inflammatory networks--a review. Liver Transpl.
16:1016–1032. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Bral M, Pawlick R, Marfil-Garza B,
Dadheech N, Hefler J, Thiesen A and Shapiro AMJ: Pan-caspase
inhibitor F573 mitigates liver ischemia reperfusion injury in a
murine model. PLoS One. 14:e02245672019. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Li H, Chen O, Ye Z, Zhang R, Hu H, Zhang
N, Huang J, Liu W and Sun X: Inhalation of high concentrations of
hydrogen ameliorates liver ischemia/reperfusion injury through A2A
receptor mediated PI3K-Akt pathway. Biochem Pharmacol. 130:83–92.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhang R, Zhang L, Manaenko A, Ye Z, Liu W
and Sun X: Helium preconditioning protects mouse liver against
ischemia and reperfusion injury through the PI3K/Akt pathway. J
Hepatol. 61:1048–1055. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Ayala A, Muñoz MF and Argüelles S: Lipid
peroxidation: Production, metabolism, and signaling mechanisms of
malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev.
2014:3604382014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Kurutas EB: The importance of antioxidants
which play the role in cellular response against
oxidative/nitrosative stress: Current state. Nutr J. 15:712016.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Kuyumcu F and Aycan A: Evaluation of
oxidative stress levels and antioxidant enzyme activities in burst
fractures. Med Sci Monit. 24:225–234. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Praveen Kumar P, Sunil Kumar KT, Kavya
Nainita M, Sai Tarun A, Raghu Ramudu BG, Deepika K, Pramoda A and
Yasmeen C: Cerebroprotective potential of hesperidin nanoparticles
against bilateral common carotid artery occlusion reperfusion
injury in rats and in silico approaches. Neurotox Res. 37:264–274.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Yuan X, Zhu J, Kang Q, He X and Guo D:
Protective effect of hesperidin against sepsis-induced lung injury
by inducing the heat-stable protein 70 (Hsp70)/Toll-like receptor 4
(TLR4)/ Myeloid differentiation primary response 88 (MyD88)
pathway. Med Sci Monit. 25:107–114. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Turk E, Kandemir FM, Yildirim S, Caglayan
C, Kucukler S and Kuzu M: Protective effect of hesperidin on sodium
arsenite-induced nephrotoxicity and hepatotoxicity in rats. Biol
Trace Elem Res. 189:95–108. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Ekinci Akdemir FN, Gülçin İ, Karagöz B,
Soslu R and Alwasel SH: A comparative study on the antioxidant
effects of hesperidin and ellagic acid against skeletal muscle
ischemia/reperfusion injury. J Enzyme Inhib Med Chem. 31
(sup4):114–118. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zhai Y, Busuttil RW and Kupiec-Weglinski
JW: Liver ischemia and reperfusion injury: New insights into
mechanisms of innate-adaptive immune-mediated tissue inflammation.
Am J Transplant. 11:1563–1569. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Huang H, Tohme S, Al-Khafaji AB, Tai S,
Loughran P, Chen L, Wang S, Kim J, Billiar T, Wang Y, et al:
Damage-associated molecular pattern-activated neutrophil
extracellular trap exacerbates sterile inflammatory liver injury.
Hepatology. 62:600–614. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Yu XH, Wang YF, Dai FY, Zhao JH and Li P:
The protective effects of berberine and hesperidin on inflammatory
factor-stimulating cardiac fibroblasts. Eur Rev Med Pharmacol Sci.
23:5468–5476. 2019.PubMed/NCBI
|
|
43
|
Ye J, Guan M, Lu Y, Zhang D, Li C, Li Y
and Zhou C: Protective effects of hesperidin on
lipopolysaccharide-induced acute lung injury by targeting MD2. Eur
J Pharmacol. 852:151–158. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Li Y, Tong L, Zhang J, Zhang Y and Zhang
F: Galangin alleviates liver ischemia-reperfusion injury in a rat
model by mediating the PI3K/AKT pathway. Cell Physiol Biochem.
51:1354–1363. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Hanchang W, Khamchan A, Wongmanee N and
Seedadee C: Hesperidin ameliorates pancreatic β-cell dysfunction
and apoptosis in streptozotocin-induced diabetic rat model. Life
Sci. 235:1168582019. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
He S, Wang X, Zhong Y, Tang L, Zhang Y,
Ling Y, Tan Z, Yang P and Chen A: Hesperetin post-treatment
prevents rat cardiomyocytes from hypoxia/reoxygenation injury in
vitro via activating PI3K/Akt signaling pathway. Biomed
Pharmacother. 91:1106–1112. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Wang JJ and Cui P: Neohesperidin
attenuates cerebral ischemia-reperfusion injury via inhibiting the
apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway. J Asian
Nat Prod Res. 15:1023–1037. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Naz H, Tarique M, Ahamad S, Alajmi MF,
Hussain A, Rehman MT, Luqman S and Hassan MI: Hesperidin-CAMKIV
interaction and its impact on cell proliferation and apoptosis in
the human hepatic carcinoma and neuroblastoma cells. J Cell
Biochem. 120:15119–15130. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Xiao Q, Ye Q, Wang W, Xiao J, Fu B, Xia Z,
Zhang X, Liu Z and Zeng X: Mild hypothermia pretreatment protects
against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a
pathway. Mol Med Rep. 16:7520–7526. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Li X, Hu X, Wang J, Xu W, Yi C, Ma R and
Jiang H: Inhibition of autophagy via activation of PI3K/Akt/mTOR
pathway contributes to the protection of hesperidin against
myocardial ischemia/reperfusion injury. Int J Mol Med.
42:1917–1924. 2018.PubMed/NCBI
|
