|
1
|
Biermann JS, Chow W, Reed DR, Lucas D,
Adkins DR, Agulnik M, Benjamin RS, Brigman B, Budd GT, Curry WT, et
al: NCCN Guidelines Insights: Bone Cancer, Version 2.2017. J Natl
Compr Canc Netw. 15:155–167. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Mirabello L, Troisi RJ and Savage SA:
Osteosarcoma incidence and survival rates from 1973 to 2004: Data
from the Surveillance, Epidemiology, and End results program.
Cancer. 115:1531–1543. 2010. View Article : Google Scholar
|
|
3
|
Siegel HJ and Pressey JG: Current concepts
on the surgical and medical management of osteosarcoma. Expert Rev
Anticancer Ther. 8:1257–1269. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Mialou V, Philip T, Kalifa C, Perol D,
Gentet JC, Marec-Berard P, Pacquement H, Chastagner P, Defaschelles
AS and Hartmann O: Metastatic osteosarcoma at diagnosis: Prognostic
factors and long-term outcome-the French pediatric experience.
Cancer. 104:1100–1109. 2010. View Article : Google Scholar
|
|
5
|
Friebele JC, Peck J, Pan X, Abdel-Rasoul M
and Mayerson JL: Osteosarcoma: A meta-analysis and review of the
literature. Am J Orthop (Belle Mead NJ). 44:547–553.
2015.PubMed/NCBI
|
|
6
|
Ma J, Li J, Zhou J, Li XL, Tang K, Zhou M,
Yang JB, Yan Q, Shen SR, Hu GX and Li GY: Profiling genes
differentially expressed in NGX6 overexpressed nasopharyngeal
carcinoma cells by cDNA array. J Cancer Res Clin Oncol.
128:683–690. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
He S, Zhong Y, Shuai C, Gao D, Wei P, Li G
and Peng S: Tumor suppressor NGX6 inhibits the growth and
metastasis of multiple cancers. Tumour Biol. 37:5751–5760. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wang L, Ma J, Li J, Li X, Zhang Q, Peng S,
Peng C, Zhou M, Xiong W, Yang J, et al: NGX6 gene inhibits cell
proliferation and plays a negative role in EGFR pathway in
nasopharyngeal carcinoma cells. 95:64–73. 2005.PubMed/NCBI
|
|
9
|
Zhang XM, Wang XY, Sheng SR, Wang JR and
Li J: Expression of tumor related genes NGX6, NAG-7, BRD7 in
gastric and colorectal cancer. World J Gastroenterol. 9:1729–1733.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Guo Q, Shen S, Liao M, Lian P and Wang X:
NGX6 inhibits cell invasion and adhesion through suppression of
Wnt/beta-catenin signal pathway in colon cancer. Acta Biochim
Biophys Sin (Shanghai). 42:450–456. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wang YT, Sun XY, Wang H, Huang TT, Wang Y
and Yang MX: Effects of NGX6 expression on proliferation and
invasion of nasopharyngeal carcinoma cells and survival of
patients. Eur Rev Med Pharmacol Sci. 21:5378–5385. 2017.PubMed/NCBI
|
|
12
|
Liu J, Zhu X, Xu X and Dai D: DNA promoter
and histone H3 methylation downregulate NGX6 in gastric cancer
cells. Med Onco. 31:8172014. View Article : Google Scholar
|
|
13
|
Lin ZF, Shen XY, Lu FZ, Ruan Z, Huang HL
and Zhen J: Reveals new lung adenocarcinoma cancer genes based on
gene expression. Eur Rev Med Pharmacol Sc. 16:1249–1256. 2012.
|
|
14
|
Nusse R and Clevers H: Wnt/β-catenin
signaling, disease, and emerging therapeutic modalities. Cell.
169:985–999. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Lin CH, Ji T, Chen CF and Hoang BH: Wnt
signaling in osteosarcoma. Adv Exp Med Biol. 804:33–45. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Anastas JN and Moon RT: WNT signalling
pathways as therapeutic targets in cancer. Nat Rev Cancer.
13:11–26. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
17
|
Takebe N, Miele L, Harris PJ, Jeong W,
Bando H, Kahn M, Yang SX and Ivy SP: Targeting Notch, Hedgehog, and
Wnt pathways in cancer stem cells: Clinical update. Nat Rev Clin
Oncol. 12:445–464. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zou J, Zhang W and Li XL: Effects of SOST
gene silencing on proliferation, apoptosis, invasion, and migration
of human osteosarcoma cells through the Wnt/β-catenin signaling
pathway. Calcif Tissue Int. 100:551–564. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tang L, Wang D and Gu D: Knockdown of Sox2
inhibits OS cells invasion and migration via modulating
Wnt/beta-catenin signaling pathway. Pathol Oncol Res. 24:907–913.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Clark DJ, Gebhart FG, Gonder CJ, Keeling
ME and Kohn DF: Special Report: The 1996 Guide for the Care and Use
of Laboratory Animals. ILAR J. 38:41–48. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Liu M, Peng Y, Wang X, Guo Q, Shen S and
Li G: NGX6 gene mediated by promoter methylation as a potential
molecular marker in colorectal cancer. Bmc Cancer. 10:160. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xiao JD and Shen SR: Expression and
significance of NGX6 gene in human hepatocellular carcinoma. Zhong
Nan Da Xue Xue Bao Yi Xue Ban. 33:937–941. 2008.(In Chinese).
PubMed/NCBI
|
|
24
|
Peng SP, Li XL, Wang L, Ou-Yang J, Ma J,
Wang LL, Liu HY, Zhou M, Tang YL, Li WS, et al: The role of NGX6
and its deletion mutants in the proliferation, adhesion and
migration of nasopharyngeal carcinoma 5-8F cells. Oncology.
71:273–281. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Logan CY and Nusse R: The Wnt signaling
pathway in development and disease. Annu Rev Cell Dev Biol.
20:781–810. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ma Y, Zhu B, Liu X, Yu H, Yong L, Liu X,
Shao J and Liu Z: Inhibition of oleandrin on the proliferation show
and invasion of osteosarcoma cells in vitro by suppressing
Wnt/β-catenin signaling pathway. J Exp Clin Cancer Res. 34:1152015.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Li R, Liu J, Wu H, Liu L, Wang L and Zhang
S: TIKI2 suppresses growth of osteosarcoma by targeting
Wnt/β-catenin pathway. Mol Cell Biochem. 392:109–116. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Lv Z, Wang C, Yuan T, Liu Y, Song T, Liu
Y, Chen C, Yang M, Tang Z, Shi Q and Weng Y: Bone morphogenetic
protein 9 regulates tumor growth of osteosarcoma cells through the
Wnt/β-catenin pathway. Oncol Rep. 31:989–994. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Guan H, Tan P, Xie L, Mi B, Fang Z, Li J,
Yue J, Liao H and Li F: FOXO1 inhibits osteosarcoma oncogenesis via
Wnt/β-catenin pathway suppression. Oncogenesis. 4:e1662015.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Guo Q, Wu M, Lian P, Liao M, Xiao Z, Wang
X and Shen S: Synergistic effect of indomethacin and NGX6 on
proliferation and invasion by human colorectal cancer cells through
modulation of the Wnt/beta-catenin signaling pathway. Mol Cell
Biochem. 330:71–81. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Liu F, Sheng S, Wang X, Peng Y, Guo Q,
Xiao Z and Liu J: Role of NGX6 in Wnt/β-catenin signaling pathway
in colon cancer. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 36:235–242.
2011.(In Chinese). PubMed/NCBI
|
